| 116234598 | 116234621 | 7 | + | 26472758 | Jiyoye | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | 1.0513215310928272 | [198] | [310] | 7 | hSpCas9 | negative selection | 163979 | 116234598 | 116234621 | 7 | + | 26472758 | KBM7 | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | 0.46214401059282095 | [1294,913] | [653,752] | 5 | hSpCas9 | negative selection | 355097 | 116234598 | 116234621 | 7 | + | 26472758 | Raji | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | 0.8104017976164678 | [429] | [174] | 7 | hSpCas9 | negative selection | 546215 | 116234598 | 116234621 | 7 | + | 26472758 | K562 | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | 0.40938884716599433 | [874] | [980] | 3 | hSpCas9 | negative selection | 737333 | 116210695 | 116210718 | 7 | + | 26627737 | DLD1 | viability | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.732443989570458 | [367] | [152,235,186] | 7 | hSpCas9 | negative selection | 834571 | 116234534 | 116234557 | 7 | + | 26627737 | DLD1 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.5847462173791105 | [393] | [236,154,163] | 6 | hSpCas9 | negative selection | 834572 | 116210695 | 116210718 | 7 | + | 26627737 | GBM cells | viability after 5 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | -0.03204448068466309 | [203] | [114,98] | 0 | hSpCas9 | negative selection | 916886 | 116234534 | 116234557 | 7 | + | 26627737 | GBM cells | viability after 5 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.2525508295003862 | [215] | [159,115] | 4 | hSpCas9 | negative selection | 916887 | 116210695 | 116210718 | 7 | + | 26627737 | GBM cells | viability after 13 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | -0.28008164083386944 | [203] | [126,61] | -3 | hSpCas9 | negative selection | 999201 | 116234534 | 116234557 | 7 | + | 26627737 | GBM cells | viability after 13 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.2027530334790468 | [215] | [108,95] | -2 | hSpCas9 | negative selection | 999202 | 116210695 | 116210718 | 7 | + | 26627737 | GBM cells | viability after 21 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | -0.5792768993229133 | [203] | [69,77] | -5 | hSpCas9 | negative selection | 1081516 | 116234534 | 116234557 | 7 | + | 26627737 | GBM cells | viability after 21 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.003090047401191759 | [215] | [126,108] | 0 | hSpCas9 | negative selection | 1081517 | 116210695 | 116210718 | 7 | + | 26627737 | RPE1 | viability after 9 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.9104282927135704 | [294] | [156,194] | 6 | hSpCas9 | negative selection | 1163831 | 116234534 | 116234557 | 7 | + | 26627737 | RPE1 | viability after 9 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.7949751504819045 | [548] | [185,442] | 5 | hSpCas9 | negative selection | 1163832 | 116210695 | 116210718 | 7 | + | 26627737 | RPE1 | viability after 12 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 1.223812692946726 | [294] | [171,198] | 7 | hSpCas9 | negative selection | 1246146 | 116234534 | 116234557 | 7 | + | 26627737 | RPE1 | viability after 12 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.9094888243289272 | [548] | [244,310] | 5 | hSpCas9 | negative selection | 1246147 | 116210695 | 116210718 | 7 | + | 26627737 | RPE1 | viability after 15 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.949735818522246 | [294] | [178,143] | 5 | hSpCas9 | negative selection | 1328461 | 116234534 | 116234557 | 7 | + | 26627737 | RPE1 | viability after 15 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 1.0073881700086382 | [548] | [244,376] | 6 | hSpCas9 | negative selection | 1328462 | 116210695 | 116210718 | 7 | + | 26627737 | RPE1 | viability after 18 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 1.1311024095242874 | [294] | [155,193] | 6 | hSpCas9 | negative selection | 1410776 | 116234534 | 116234557 | 7 | + | 26627737 | RPE1 | viability after 18 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.5088732007899911 | [548] | [190,231] | 3 | hSpCas9 | negative selection | 1410777 | 116210695 | 116210718 | 7 | + | 26627737 | HeLa | viability after 8 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.23518930901794854 | [225] | [182,17,157] | 2 | hSpCas9 | negative selection | 1493091 | 116234534 | 116234557 | 7 | + | 26627737 | HeLa | viability after 8 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.4287625192520338 | [494] | [210,145,135] | -4 | hSpCas9 | negative selection | 1493092 | 116210695 | 116210718 | 7 | + | 26627737 | HeLa | viability after 12 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.029394514341778755 | [225] | [202,48,41] | 0 | hSpCas9 | negative selection | 1575406 | 116234534 | 116234557 | 7 | + | 26627737 | HeLa | viability after 12 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.15851568963939833 | [494] | [284,186,218] | 1 | hSpCas9 | negative selection | 1575407 | 116210695 | 116210718 | 7 | + | 26627737 | HeLa | viability after 15 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.4385248912032908 | [225] | [232,22,115] | 3 | hSpCas9 | negative selection | 1657721 | 116234534 | 116234557 | 7 | + | 26627737 | HeLa | viability after 15 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.2856197326835125 | [494] | [290,275,162] | 2 | hSpCas9 | negative selection | 1657722 | 116210695 | 116210718 | 7 | + | 26627737 | HeLa | viability after 18 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.49697987481430267 | [225] | [167,16,115] | 4 | hSpCas9 | negative selection | 1740036 | 116234534 | 116234557 | 7 | + | 26627737 | HeLa | viability after 18 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.316449986248467 | [494] | [201,232,162] | 2 | hSpCas9 | negative selection | 1740037 | 116210695 | 116210718 | 7 | + | 26627737 | HCT116 | viability after 6 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.5518736603678633 | [300] | [118,41] | 3 | hSpCas9 | negative selection | 1822351 | 116234534 | 116234557 | 7 | + | 26627737 | HCT116 | viability after 6 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.03634233306367493 | [734] | [209,58] | 0 | hSpCas9 | negative selection | 1822352 | 116210695 | 116210718 | 7 | + | 26627737 | HCT116 | viability after 8 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.44583754940690556 | [143] | [85,59,176] | 4 | hSpCas9 | negative selection | 1904666 | 116234534 | 116234557 | 7 | + | 26627737 | HCT116 | viability after 8 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.9925441851347694 | [416] | [118,151,75] | -8 | hSpCas9 | negative selection | 1904667 | 116210695 | 116210718 | 7 | + | 26627737 | HCT116 | viability after 9 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.7912459585751197 | [300] | [142,135] | 5 | hSpCas9 | negative selection | 1986981 | 116234534 | 116234557 | 7 | + | 26627737 | HCT116 | viability after 9 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.2827871230409452 | [734] | [221,251] | 2 | hSpCas9 | negative selection | 1986982 | 116210695 | 116210718 | 7 | + | 26627737 | HCT116 | viability after 12 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.31438559752274364 | [143] | [49,127,108] | 3 | hSpCas9 | negative selection | 2069296 | 116234534 | 116234557 | 7 | + | 26627737 | HCT116 | viability after 12 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.3718463520966119 | [416] | [82,183,248] | -4 | hSpCas9 | negative selection | 2069297 | 116210695 | 116210718 | 7 | + | 26627737 | HCT116 | viability after 15 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.3919875884034588 | [143] | [84,154,82] | 4 | hSpCas9 | negative selection | 2151611 | 116234534 | 116234557 | 7 | + | 26627737 | HCT116 | viability after 15 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.6225769535913619 | [416] | [117,265,78] | -6 | hSpCas9 | negative selection | 2151612 | 116210695 | 116210718 | 7 | + | 26627737 | HCT116 | viability after 18 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.8210583100190258 | [143] | [55,175,133] | 6 | hSpCas9 | negative selection | 2233926 | 116234534 | 116234557 | 7 | + | 26627737 | HCT116 | viability after 18 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.3636842559241541 | [416] | [87,227,148] | -3 | hSpCas9 | negative selection | 2233927 | 116222802 | 116222825 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAAATAAATAGGAGGTTTTGAGG | TES | ENSG00000135269 | -0.4416363643804735 | [37,73] | [9,6] | -2 | dCas9-VP64 | positive selection | 2467641 | 116222751 | 116222774 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GAACTCCTACAGATGCGTTTTGG | TES | ENSG00000135269 | 1.6239811972228262 | [288,40] | [203,8] | 6 | dCas9-VP64 | positive selection | 2467642 | 116222756 | 116222779 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGATTCCAAAACGCATCTGTAGG | TES | ENSG00000135269 | -0.2165694481652165 | [335,53] | [52,18] | -1 | dCas9-VP64 | positive selection | 2467643 | 116222802 | 116222825 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAAATAAATAGGAGGTTTTGAGG | TES | ENSG00000135269 | -1.0662247292057987 | [460,37] | [74,4] | -8 | dCas9-VP64 | positive selection | 2562896 | 116222751 | 116222774 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GAACTCCTACAGATGCGTTTTGG | TES | ENSG00000135269 | -0.744845405221779 | [39,131] | [13,17] | -7 | dCas9-VP64 | positive selection | 2562897 | 116222756 | 116222779 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGATTCCAAAACGCATCTGTAGG | TES | ENSG00000135269 | -0.36277127907226264 | [185,207] | [71,28] | -4 | dCas9-VP64 | positive selection | 2562898 | 116234534 | 116234557 | | + | 24336571 | A375 | resistance to PLX after 7 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.2178882640628027 | [15,15] | [12,13] | -6 | hSpCas9 | positive selection | 3149756 | 116234534 | 116234557 | | + | 24336571 | A375 | resistance to PLX after 14 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.44743259636208266 | [19,10] | [5,3] | -5 | hSpCas9 | positive selection | 3207549 | 116234534 | 116234557 | | + | 24336571 | A375 | viability after 7 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.3584251854548235 | [12] | [15,15] | 5 | hSpCas9 | negative selection | 3265342 | 116234534 | 116234557 | | + | 24336571 | A375 | viability after 14 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.339475193575398 | [12] | [19,10] | 4 | hSpCas9 | negative selection | 3323135 | 116234534 | 116234557 | 7 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.4841407749553118 | [213,213] | [0,0] | -3 | hSpCas9 | positive selection | 3396766 | 116234598 | 116234621 | 7 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | -0.565123819989597 | [] | [] | 0 | hSpCas9 | negative selection | 3567941 | 116234598 | 116234621 | 7 | + | 26780180 | A375 | viability (Avana lentiGuide) | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | -3.00860642712871 | [] | [] | -5 | hSpCas9 | negative selection | 3676600 | 116234598 | 116234621 | 7 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | -0.1895577676952319 | [5] | [5,3] | -3 | hSpCas9 | positive selection | 3785207 | 116234598 | 116234621 | 7 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | 0.21156019178324392 | [5] | [5,5] | 5 | hSpCas9 | positive selection | 3893814 | 116234534 | 116234557 | 7 | + | 26780180 | A375 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 1.19596521250649 | [] | [] | 6 | hSpCas9 | negative selection | 4003168 | 116234534 | 116234557 | 7 | + | 26780180 | HT29 | viability (GeCKOv2 library) | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 1.78398601108825 | [] | [] | 8 | hSpCas9 | negative selection | 4111134 | 116234534 | 116234557 | 7 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.02740824225780658 | [3] | [2,2] | 0 | hSpCas9 | positive selection | 4176116 | 116234534 | 116234557 | 7 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.8462522120397814 | [3] | [1,2,1,3] | 5 | hSpCas9 | positive selection | 4240138 | 116234534 | 116234557 | 7 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.0955785459664071 | [2] | [2,1] | -2 | hSpCas9 | positive selection | 4366899 | 116210535 | 116210558 | 7 | + | 27661255 | K562 | viability | GCCCGCTGCGGCGGACTGGGCGG | TES | ENSG00000135269 | 0.3156738265645622 | [231,285] | [289,227] | 8 | dCas9-KRAB | negative selection | 5516773 | 116210599 | 116210622 | 7 | - | 27661255 | K562 | viability | GGAAACCTGCGGAACTCCCGCGG | TES | ENSG00000135269 | 0.04887847055263414 | [619,626] | [560,475] | 1 | dCas9-KRAB | negative selection | 5516774 | 116234534 | 116234557 | 7 | + | 27260156 | BXPC3 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.16408780960390906 | [446] | [326,396,469,492] | -4 | hSpCas9 | negative selection | 5639359 | 116234534 | 116234557 | 7 | + | 27260156 | A673 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.1990336432247916 | [446] | [466,444,469,488] | -5 | hSpCas9 | negative selection | 5760610 | 116234534 | 116234557 | 7 | + | 27260156 | A375 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.08913218623844262 | [446] | [402,423,555,559] | -1 | hSpCas9 | negative selection | 5881861 | 116234534 | 116234557 | 7 | + | 27260156 | COLO741 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.08271803004197519 | [446] | [705,419,506] | -2 | hSpCas9 | negative selection | 6003112 | 116234534 | 116234557 | 7 | + | 27260156 | CAL120 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.02795578373315369 | [446] | [509,456,661] | 0 | hSpCas9 | negative selection | 6124363 | 116234534 | 116234557 | 7 | + | 27260156 | CADOES1 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.06644314154469082 | [446] | [444,536,267,335] | -1 | hSpCas9 | negative selection | 6245614 | 116234534 | 116234557 | 7 | + | 27260156 | EWS502 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.30654242463487014 | [446] | [405,544,289,269] | -5 | hSpCas9 | negative selection | 6366865 | 116234534 | 116234557 | 7 | + | 27260156 | EW8 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.06958816495889102 | [446] | [354,396,426,329] | 1 | hSpCas9 | negative selection | 6488116 | 116234534 | 116234557 | 7 | + | 27260156 | CORL105 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.15291384149496645 | [446] | [509,319,580,492] | -3 | hSpCas9 | negative selection | 6609367 | 116234534 | 116234557 | 7 | + | 27260156 | HS294T | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.3205227669980971 | [446] | [109,128,149,172] | -4 | hSpCas9 | negative selection | 6730618 | 116234534 | 116234557 | 7 | + | 27260156 | HCC44 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.40230559961602996 | [446] | [342,398,409,373] | -6 | hSpCas9 | negative selection | 6851869 | 116234534 | 116234557 | 7 | + | 27260156 | G402 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.44839624399407013 | [446] | [984,603,312,1081] | 5 | hSpCas9 | negative selection | 6973120 | 116234534 | 116234557 | 7 | + | 27260156 | L33 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.2938512273654126 | [446] | [332,136,242,404] | -6 | hSpCas9 | negative selection | 7094371 | 116234534 | 116234557 | 7 | + | 27260156 | K562 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.37526741951555104 | [446] | [795,606,469,242] | 5 | hSpCas9 | negative selection | 7215622 | 116234534 | 116234557 | 7 | + | 27260156 | HT29 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.007332374954785892 | [446] | [741,468,542,427] | 0 | hSpCas9 | negative selection | 7336873 | 116234534 | 116234557 | 7 | + | 27260156 | MHHES1 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.08131704643669282 | [446] | [658,567,654,308] | 1 | hSpCas9 | negative selection | 7458124 | 116234534 | 116234557 | 7 | + | 27260156 | MEWO | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.11776105982129273 | [446] | [506,351,512] | 2 | hSpCas9 | negative selection | 7579375 | 116234534 | 116234557 | 7 | + | 27260156 | LNCAPCLONEFGC | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.07701323890692707 | [446] | [424,452,517,323] | 1 | hSpCas9 | negative selection | 7700626 | 116234534 | 116234557 | 7 | + | 27260156 | PANC0327 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.5222621255400843 | [446] | [284,92,248,502] | -6 | hSpCas9 | negative selection | 7821877 | 116234534 | 116234557 | 7 | + | 27260156 | NCIH2009 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.06617482831913203 | [446] | [920,555,537] | 0 | hSpCas9 | negative selection | 7943128 | 116234534 | 116234557 | 7 | + | 27260156 | NCIH1373 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.3689775209857013 | [446] | [729,718,699,111] | 3 | hSpCas9 | negative selection | 8064379 | 116234534 | 116234557 | 7 | + | 27260156 | PATU8902 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.23713020108277327 | [446] | [548,469,505,596] | -2 | hSpCas9 | negative selection | 8185630 | 116234534 | 116234557 | 7 | + | 27260156 | PANC1 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.16815894189004177 | [446] | [596,390,502,246] | 2 | hSpCas9 | negative selection | 8306881 | 116234534 | 116234557 | 7 | + | 27260156 | PANC0813 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.3171793878434288 | [446] | [389,526,399,367] | -5 | hSpCas9 | negative selection | 8428132 | 116234534 | 116234557 | 7 | + | 27260156 | RDES | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.0806637954707977 | [446] | [381,586,606,628] | 1 | hSpCas9 | negative selection | 8549383 | 116234534 | 116234557 | 7 | + | 27260156 | PC3 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.013650592037215109 | [446] | [284,459,690,449] | 0 | hSpCas9 | negative selection | 8670634 | 116234534 | 116234557 | 7 | + | 27260156 | PATU8988T | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.01093780540471663 | [446] | [677,283,292,476] | 0 | hSpCas9 | negative selection | 8791885 | 116234534 | 116234557 | 7 | + | 27260156 | T47D | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.07695523131198283 | [446] | [470,503,685,536] | 1 | hSpCas9 | negative selection | 8913136 | 116234534 | 116234557 | 7 | + | 27260156 | SU8686 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.1509149653170358 | [446] | [343,284,524,476] | -3 | hSpCas9 | negative selection | 9034387 | 116234534 | 116234557 | 7 | + | 27260156 | SKES1 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.30616724547885554 | [446] | [771,585,429,458] | 6 | hSpCas9 | negative selection | 9155638 | 116234534 | 116234557 | 7 | + | 27260156 | TOV112D | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.13217310844902438 | [446] | [527,403,426,581] | 2 | hSpCas9 | negative selection | 9276889 | 116234534 | 116234557 | 7 | + | 27260156 | TC71 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.031050994542989284 | [446] | [498,379,465,621] | 0 | hSpCas9 | negative selection | 9398140 | 116234534 | 116234557 | 7 | + | 27260156 | TC32 | viability | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.24944692013471287 | [446] | [404,186,483,398] | -4 | hSpCas9 | negative selection | 9519391 | 116210695 | 116210718 | 7 | + | 27869803 | HPAFII | viability after 27 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.4759308476356668 | [207] | [120,177,NaN] | 4 | hSpCas9 | negative selection | 9597675 | 116234534 | 116234557 | 7 | + | 27869803 | HPAFII | viability after 27 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.1515213995688844 | [304] | [211,87,NaN] | -1 | hSpCas9 | negative selection | 9597676 | 116210695 | 116210718 | 7 | + | 27869803 | HPAFII | viability after 15 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | -0.06260164093205772 | [207] | [226,205,NaN] | 0 | hSpCas9 | negative selection | 9680124 | 116234534 | 116234557 | 7 | + | 27869803 | HPAFII | viability after 15 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.3113118193570955 | [304] | [616,275,NaN] | 3 | hSpCas9 | negative selection | 9680125 | 116210695 | 116210718 | 7 | + | 27869803 | ASPC1 | viability after 36 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | -0.8419689161086601 | [610] | [171,96,97] | -7 | hSpCas9 | negative selection | 9762573 | 116234534 | 116234557 | 7 | + | 27869803 | ASPC1 | viability after 36 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -1.02857909050603 | [680] | [89,191,73] | -7 | hSpCas9 | negative selection | 9762574 | 116210695 | 116210718 | 7 | + | 27869803 | PATU8988S | viability after 35 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.10161126969306183 | [446] | [265,119,NaN] | 1 | hSpCas9 | negative selection | 9845022 | 116234534 | 116234557 | 7 | + | 27869803 | PATU8988S | viability after 35 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.1670498697051643 | [448] | [217,187,NaN] | 2 | hSpCas9 | negative selection | 9845023 | 116210695 | 116210718 | 7 | + | 27869803 | PATU8988S | viability after 31 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | -0.14493966086234145 | [446] | [169,149,NaN] | -2 | hSpCas9 | negative selection | 9927471 | 116234534 | 116234557 | 7 | + | 27869803 | PATU8988S | viability after 31 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | 0.6458327088003231 | [448] | [313,236,NaN] | 7 | hSpCas9 | negative selection | 9927472 | 116210695 | 116210718 | 7 | + | 27869803 | HPAFII | viability after 35 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 0.3427504948304877 | [207] | [30,248,NaN] | 2 | hSpCas9 | negative selection | 10009920 | 116234534 | 116234557 | 7 | + | 27869803 | HPAFII | viability after 35 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.09808019315369512 | [304] | [187,94,NaN] | 0 | hSpCas9 | negative selection | 10009921 | 116210695 | 116210718 | 7 | + | 27869803 | HPAFII | viability after 31 days | AGGACGCGTTAACATGGACCTGG | TES | ENSG00000135269 | 1.0067710395550105 | [207] | [101,378,NaN] | 7 | hSpCas9 | negative selection | 10092369 | 116234534 | 116234557 | 7 | + | 27869803 | HPAFII | viability after 31 days | ATGGGCTTAGGTCACGAGCAAGG | TES | ENSG00000135269 | -0.2360487736729657 | [304] | [163,124,NaN] | -2 | hSpCas9 | negative selection | 10092370 | 116234598 | 116234621 | 7 | + | 28162770 | P31FUJ | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | -0.6530763520593696 | [367] | [274] | -5 | hSpCas9 | negative selection | 10249255 | 116234598 | 116234621 | 7 | + | 28162770 | TF1 | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | NaN | [NaN] | [238] | 1 | hSpCas9 | negative selection | 10418621 | 116234598 | 116234621 | 7 | + | 28162770 | SKM1 | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | 0.19467704312462497 | [128] | [260] | 2 | hSpCas9 | negative selection | 10587987 | 116234598 | 116234621 | 7 | + | 28162770 | SKM1 | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | 0.19467704312462497 | [128] | [260] | 2 | hSpCas9 | negative selection | 10757353 | 116234598 | 116234621 | 7 | + | 28162770 | PL21 | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | -0.03716451625105621 | [388] | [164] | 0 | hSpCas9 | negative selection | 10926719 | 116234598 | 116234621 | 7 | + | 28162770 | P31FUJ | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | -0.6530763520593696 | [367] | [274] | -5 | hSpCas9 | negative selection | 11096085 | 116234598 | 116234621 | 7 | + | 28162770 | OCIAML5 | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | 0.4173424769739381 | [206] | [498] | 3 | hSpCas9 | negative selection | 11265451 | 116234598 | 116234621 | 7 | + | 28162770 | EOL1 | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | 1.1735969865408011 | [811] | [964] | 8 | hSpCas9 | negative selection | 11434817 | 116234598 | 116234621 | 7 | + | 28162770 | MOLM13 | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | 0.33331335985771315 | [639] | [582] | 2 | hSpCas9 | negative selection | 11604183 | 116234598 | 116234621 | 7 | + | 28162770 | HEL | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | 0.48258160680686557 | [551] | [493] | 4 | hSpCas9 | negative selection | 11773549 | 116234598 | 116234621 | 7 | + | 28162770 | MV411 | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | 0.0915019445695957 | [448] | [402] | 0 | hSpCas9 | negative selection | 11942915 | 116234598 | 116234621 | 7 | + | 28162770 | MONOMAC1 | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | 0.6856062023022876 | [223] | [412] | 6 | hSpCas9 | negative selection | 12112281 | 116234598 | 116234621 | 7 | + | 28162770 | OCIAML2 | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | -0.09504159719519767 | [94] | [492] | -1 | hSpCas9 | negative selection | 12281647 | 116234598 | 116234621 | 7 | + | 28162770 | OCIAML3 | viability | GATTCGAACTGCACTTCTGGAGG | TES | ENSG00000135269 | -0.4463640862578572 | [115] | [256] | -3 | hSpCas9 | negative selection | 12451013 |