Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10210
• Symbol:Topors
• Description:TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase

DataSource: http://genomecrispr.dkfz.de/#!/results/Topors

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
32543887	32543910	9	+	26472758	Jiyoye	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.5981899883300403	[331]	[378]	4	hSpCas9	negative selection	170521
32543029	32543052	9	+	26472758	Jiyoye	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	-0.0470005116799288	[273]	[199]	0	hSpCas9	negative selection	170522
32543821	32543844	9	+	26472758	Jiyoye	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.5929209004305849	[130]	[148]	4	hSpCas9	negative selection	170523
32542359	32542382	9	-	26472758	Jiyoye	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	0.1752286534561766	[100]	[85]	1	hSpCas9	negative selection	170524
32543985	32544008	9	+	26472758	Jiyoye	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.9876364899920889	[106]	[159]	6	hSpCas9	negative selection	170525
32542381	32542404	9	-	26472758	Jiyoye	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	0.6230837692721226	[222]	[258]	4	hSpCas9	negative selection	170526
32542144	32542167	9	-	26472758	Jiyoye	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	-2.2152618246339455	[116]	[18]	-8	hSpCas9	negative selection	170527
32543903	32543926	9	-	26472758	Jiyoye	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	0.592390253972781	[72]	[82]	4	hSpCas9	negative selection	170528
32543277	32543300	9	+	26472758	Jiyoye	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	0.4956441693681872	[252]	[268]	4	hSpCas9	negative selection	170529
32543167	32543190	9	-	26472758	Jiyoye	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	-0.8558590243279205	[239]	[99]	-6	hSpCas9	negative selection	170530
32543887	32543910	9	+	26472758	KBM7	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.08542746464714357	[1563,1001]	[735,532]	0	hSpCas9	negative selection	361639
32543029	32543052	9	+	26472758	KBM7	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	0.2390758785422571	[1034,1007]	[514,616]	2	hSpCas9	negative selection	361640
32543821	32543844	9	+	26472758	KBM7	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.1469733917353524	[253,392]	[192,154]	1	hSpCas9	negative selection	361641
32542359	32542382	9	-	26472758	KBM7	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	0.2975044826767911	[355,275]	[206,157]	3	hSpCas9	negative selection	361642
32543985	32544008	9	+	26472758	KBM7	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	-0.19331998084057817	[884,655]	[349,280]	-2	hSpCas9	negative selection	361643
32542381	32542404	9	-	26472758	KBM7	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	0.2057788805002212	[1460,733]	[853,330]	2	hSpCas9	negative selection	361644
32542144	32542167	9	-	26472758	KBM7	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	-0.22908590273541263	[173,175]	[68,71]	-2	hSpCas9	negative selection	361645
32543903	32543926	9	-	26472758	KBM7	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	0.5455610982942788	[298,441]	[278,243]	6	hSpCas9	negative selection	361646
32543277	32543300	9	+	26472758	KBM7	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	-0.12608144466189075	[1151,1446]	[604,536]	-1	hSpCas9	negative selection	361647
32543167	32543190	9	-	26472758	KBM7	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	0.037504095470887955	[834,762]	[372,396]	0	hSpCas9	negative selection	361648
32543887	32543910	9	+	26472758	Raji	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.11772547959505864	[833]	[209]	1	hSpCas9	negative selection	552757
32543029	32543052	9	+	26472758	Raji	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	-0.1356368473495777	[586]	[123]	-1	hSpCas9	negative selection	552758
32543821	32543844	9	+	26472758	Raji	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	-0.6184415011874065	[171]	[25]	-5	hSpCas9	negative selection	552759
32542359	32542382	9	-	26472758	Raji	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	1.0898961086447585	[82]	[40]	8	hSpCas9	negative selection	552760
32543985	32544008	9	+	26472758	Raji	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.339199210596673	[326]	[95]	3	hSpCas9	negative selection	552761
32542381	32542404	9	-	26472758	Raji	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	0.2905058391974886	[531]	[150]	2	hSpCas9	negative selection	552762
32542144	32542167	9	-	26472758	Raji	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	0.8894785050294653	[106]	[45]	7	hSpCas9	negative selection	552763
32543903	32543926	9	-	26472758	Raji	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	0.6098838759027826	[143]	[50]	6	hSpCas9	negative selection	552764
32543277	32543300	9	+	26472758	Raji	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	0.5665604633860164	[514]	[176]	5	hSpCas9	negative selection	552765
32543167	32543190	9	-	26472758	Raji	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	0.1836191212006847	[386]	[101]	1	hSpCas9	negative selection	552766
32543887	32543910	9	+	26472758	K562	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.4319387734309752	[986]	[1123]	3	hSpCas9	negative selection	743875
32543029	32543052	9	+	26472758	K562	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	0.296942334931956	[916]	[950]	2	hSpCas9	negative selection	743876
32543821	32543844	9	+	26472758	K562	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	-0.18572566400260526	[255]	[189]	-1	hSpCas9	negative selection	743877
32542359	32542382	9	-	26472758	K562	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	-0.25565487546819626	[296]	[209]	-2	hSpCas9	negative selection	743878
32543985	32544008	9	+	26472758	K562	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.04144651156215606	[700]	[608]	0	hSpCas9	negative selection	743879
32542381	32542404	9	-	26472758	K562	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	0.34662120059735546	[1116]	[1198]	2	hSpCas9	negative selection	743880
32542144	32542167	9	-	26472758	K562	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	0.16760313061561605	[134]	[127]	1	hSpCas9	negative selection	743881
32543903	32543926	9	-	26472758	K562	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	0.5065489059301267	[265]	[318]	4	hSpCas9	negative selection	743882
32543277	32543300	9	+	26472758	K562	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	2.0615340833803812	[946]	[3336]	9	hSpCas9	negative selection	743883
32543167	32543190	9	-	26472758	K562	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	-0.39396283878868654	[673]	[432]	-3	hSpCas9	negative selection	743884
32542097	32542120	9	-	26627737	DLD1	viability	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	-0.1644016215172706	[385]	[107,89,121]	-2	hSpCas9	negative selection	842625
32543374	32543397	9	+	26627737	DLD1	viability	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	2.590203470614134	[20]	[39,58,22]	9	hSpCas9	negative selection	842626
32543811	32543834	9	-	26627737	DLD1	viability	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	-0.09512725745442663	[971]	[193,369,291]	-1	hSpCas9	negative selection	842627
32550872	32550895	9	-	26627737	DLD1	viability	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-2.3378538942092337	[106]	[14,0,3]	-9	hSpCas9	negative selection	842628
32550882	32550905	9	+	26627737	DLD1	viability	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	0.37314902394595817	[787]	[245,473,253]	4	hSpCas9	negative selection	842629
32550925	32550948	9	-	26627737	DLD1	viability	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.5896109844993069	[503]	[311,258,153]	6	hSpCas9	negative selection	842630
32542097	32542120	9	-	26627737	GBM cells	viability after 5 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	-0.36412053094810826	[335]	[147,131]	-5	hSpCas9	negative selection	924940
32543374	32543397	9	+	26627737	GBM cells	viability after 5 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	0.05697872111793689	[94]	[48,56]	0	hSpCas9	negative selection	924941
32543811	32543834	9	-	26627737	GBM cells	viability after 5 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.15525362814547128	[539]	[291,352]	2	hSpCas9	negative selection	924942
32550872	32550895	9	-	26627737	GBM cells	viability after 5 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-0.9182220679645043	[36]	[13,6]	-8	hSpCas9	negative selection	924943
32550882	32550905	9	+	26627737	GBM cells	viability after 5 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.13956027292895	[455]	[261,181]	-2	hSpCas9	negative selection	924944
32550925	32550948	9	-	26627737	GBM cells	viability after 5 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.19972162335140464	[288]	[183,171]	3	hSpCas9	negative selection	924945
32542097	32542120	9	-	26627737	GBM cells	viability after 13 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	-0.12504975681875008	[335]	[234,111]	-1	hSpCas9	negative selection	1007255
32543374	32543397	9	+	26627737	GBM cells	viability after 13 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	0.056091917799210966	[94]	[57,49]	0	hSpCas9	negative selection	1007256
32543811	32543834	9	-	26627737	GBM cells	viability after 13 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.20053812272321636	[539]	[323,346]	2	hSpCas9	negative selection	1007257
32550872	32550895	9	-	26627737	GBM cells	viability after 13 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	0.2985734316361883	[36]	[27,21]	4	hSpCas9	negative selection	1007258
32550882	32550905	9	+	26627737	GBM cells	viability after 13 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.12157716348863024	[455]	[163,278]	-1	hSpCas9	negative selection	1007259
32550925	32550948	9	-	26627737	GBM cells	viability after 13 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.2699249222061135	[288]	[182,193]	3	hSpCas9	negative selection	1007260
32542097	32542120	9	-	26627737	GBM cells	viability after 21 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.15640695119192294	[335]	[239,169]	1	hSpCas9	negative selection	1089570
32543374	32543397	9	+	26627737	GBM cells	viability after 21 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	-1.2418961907302715	[94]	[25,17]	-8	hSpCas9	negative selection	1089571
32543811	32543834	9	-	26627737	GBM cells	viability after 21 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.5492974043693131	[539]	[468,392]	5	hSpCas9	negative selection	1089572
32550872	32550895	9	-	26627737	GBM cells	viability after 21 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	0.33437756896917126	[36]	[28,21]	3	hSpCas9	negative selection	1089573
32550882	32550905	9	+	26627737	GBM cells	viability after 21 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.13113073094083239	[455]	[232,219]	-1	hSpCas9	negative selection	1089574
32550925	32550948	9	-	26627737	GBM cells	viability after 21 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.36169275259694894	[288]	[195,206]	4	hSpCas9	negative selection	1089575
32542097	32542120	9	-	26627737	RPE1	viability after 9 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	-0.1862676463592609	[1151]	[240,414]	-1	hSpCas9	negative selection	1171885
32543374	32543397	9	+	26627737	RPE1	viability after 9 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	1.7109052301924101	[59]	[57,65]	8	hSpCas9	negative selection	1171886
32543811	32543834	9	-	26627737	RPE1	viability after 9 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.6843365838633336	[1193]	[322,958]	4	hSpCas9	negative selection	1171887
32550872	32550895	9	-	26627737	RPE1	viability after 9 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-1.6232904440977105	[185]	[0,41]	-8	hSpCas9	negative selection	1171888
32550882	32550905	9	+	26627737	RPE1	viability after 9 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.26438140460544535	[2175]	[495,658]	-2	hSpCas9	negative selection	1171889
32550925	32550948	9	-	26627737	RPE1	viability after 9 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.5362114887903604	[828]	[247,541]	3	hSpCas9	negative selection	1171890
32542097	32542120	9	-	26627737	RPE1	viability after 12 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	-0.07919742431684557	[1151]	[223,365]	0	hSpCas9	negative selection	1254200
32543374	32543397	9	+	26627737	RPE1	viability after 12 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	1.9500502187839417	[59]	[37,87]	8	hSpCas9	negative selection	1254201
32543811	32543834	9	-	26627737	RPE1	viability after 12 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.7177469155563422	[1193]	[359,704]	4	hSpCas9	negative selection	1254202
32550872	32550895	9	-	26627737	RPE1	viability after 12 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-5.643047399434894	[185]	[0,0]	-9	hSpCas9	negative selection	1254203
32550882	32550905	9	+	26627737	RPE1	viability after 12 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.36825719455418415	[2175]	[585,311]	-3	hSpCas9	negative selection	1254204
32550925	32550948	9	-	26627737	RPE1	viability after 12 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.5760467023820014	[828]	[366,294]	4	hSpCas9	negative selection	1254205
32542097	32542120	9	-	26627737	RPE1	viability after 15 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	-0.6721552522089095	[1151]	[203,204]	-4	hSpCas9	negative selection	1336515
32543374	32543397	9	+	26627737	RPE1	viability after 15 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	2.3858897402758963	[59]	[104,72]	9	hSpCas9	negative selection	1336516
32543811	32543834	9	-	26627737	RPE1	viability after 15 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	1.1847246960545426	[1193]	[610,918]	6	hSpCas9	negative selection	1336517
32550872	32550895	9	-	26627737	RPE1	viability after 15 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-5.7174099372361376	[185]	[0,0]	-9	hSpCas9	negative selection	1336518
32550882	32550905	9	+	26627737	RPE1	viability after 15 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.8305386962902905	[2175]	[394,298]	-5	hSpCas9	negative selection	1336519
32550925	32550948	9	-	26627737	RPE1	viability after 15 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.7477768893257165	[828]	[405,381]	4	hSpCas9	negative selection	1336520
32542097	32542120	9	-	26627737	RPE1	viability after 18 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.010853931520201976	[1151]	[290,336]	0	hSpCas9	negative selection	1418830
32543374	32543397	9	+	26627737	RPE1	viability after 18 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	2.241014348450422	[59]	[106,43]	9	hSpCas9	negative selection	1418831
32543811	32543834	9	-	26627737	RPE1	viability after 18 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.9885234673639288	[1193]	[488,799]	6	hSpCas9	negative selection	1418832
32550872	32550895	9	-	26627737	RPE1	viability after 18 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-2.909110292428318	[185]	[11,0]	-9	hSpCas9	negative selection	1418833
32550882	32550905	9	+	26627737	RPE1	viability after 18 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.4319959145121888	[2175]	[457,410]	-3	hSpCas9	negative selection	1418834
32550925	32550948	9	-	26627737	RPE1	viability after 18 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.6319701898585127	[828]	[366,324]	4	hSpCas9	negative selection	1418835
32542097	32542120	9	-	26627737	HeLa	viability after 8 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.52819253993365	[284]	[217,160,166]	5	hSpCas9	negative selection	1501145
32543374	32543397	9	+	26627737	HeLa	viability after 8 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	-0.41858010413892255	[218]	[70,88,54]	-4	hSpCas9	negative selection	1501146
32543811	32543834	9	-	26627737	HeLa	viability after 8 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.287340468996899	[771]	[493,338,414]	2	hSpCas9	negative selection	1501147
32550872	32550895	9	-	26627737	HeLa	viability after 8 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-1.0505742805816798	[76]	[17,0,28]	-8	hSpCas9	negative selection	1501148
32550882	32550905	9	+	26627737	HeLa	viability after 8 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.35081035355203266	[618]	[191,86,340]	-3	hSpCas9	negative selection	1501149
32550925	32550948	9	-	26627737	HeLa	viability after 8 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.6253797920615434	[260]	[246,68,221]	5	hSpCas9	negative selection	1501150
32542097	32542120	9	-	26627737	HeLa	viability after 12 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.09533256483725666	[284]	[88,157,125]	0	hSpCas9	negative selection	1583460
32543374	32543397	9	+	26627737	HeLa	viability after 12 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	-0.2609844877842773	[218]	[96,1,135]	-2	hSpCas9	negative selection	1583461
32543811	32543834	9	-	26627737	HeLa	viability after 12 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.026887683865093548	[771]	[301,385,279]	0	hSpCas9	negative selection	1583462
32550872	32550895	9	-	26627737	HeLa	viability after 12 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-2.0904869596403146	[76]	[3,0,17]	-9	hSpCas9	negative selection	1583463
32550882	32550905	9	+	26627737	HeLa	viability after 12 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.711151523445599	[618]	[122,144,200]	-6	hSpCas9	negative selection	1583464
32550925	32550948	9	-	26627737	HeLa	viability after 12 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.8491275866027246	[260]	[238,167,179]	6	hSpCas9	negative selection	1583465
32542097	32542120	9	-	26627737	HeLa	viability after 15 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.2925417129628938	[284]	[38,193,198]	2	hSpCas9	negative selection	1665775
32543374	32543397	9	+	26627737	HeLa	viability after 15 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	-0.8626862850451957	[218]	[25,76,43]	-6	hSpCas9	negative selection	1665776
32543811	32543834	9	-	26627737	HeLa	viability after 15 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.2086605312985541	[771]	[467,307,307]	1	hSpCas9	negative selection	1665777
32550872	32550895	9	-	26627737	HeLa	viability after 15 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	1.0511014354065238	[76]	[60,79,52]	7	hSpCas9	negative selection	1665778
32550882	32550905	9	+	26627737	HeLa	viability after 15 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	0.544315248262666	[618]	[287,429,386]	4	hSpCas9	negative selection	1665779
32550925	32550948	9	-	26627737	HeLa	viability after 15 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.711263035321462	[260]	[253,66,201]	5	hSpCas9	negative selection	1665780
32542097	32542120	9	-	26627737	HeLa	viability after 18 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.28481066907451	[284]	[25,158,198]	2	hSpCas9	negative selection	1748090
32543374	32543397	9	+	26627737	HeLa	viability after 18 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	-0.857424431287247	[218]	[15,65,43]	-6	hSpCas9	negative selection	1748091
32543811	32543834	9	-	26627737	HeLa	viability after 18 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.17134516074261708	[771]	[303,244,307]	1	hSpCas9	negative selection	1748092
32550872	32550895	9	-	26627737	HeLa	viability after 18 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	1.081353436797018	[76]	[42,66,52]	7	hSpCas9	negative selection	1748093
32550882	32550905	9	+	26627737	HeLa	viability after 18 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	0.5372757287017597	[618]	[188,356,386]	4	hSpCas9	negative selection	1748094
32550925	32550948	9	-	26627737	HeLa	viability after 18 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.7009599942009181	[260]	[165,57,201]	5	hSpCas9	negative selection	1748095
32542097	32542120	9	-	26627737	HCT116	viability after 6 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.3684841116262165	[678]	[102,156]	2	hSpCas9	negative selection	1830405
32543374	32543397	9	+	26627737	HCT116	viability after 6 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	-1.1118064539245047	[174]	[33,0]	-6	hSpCas9	negative selection	1830406
32543811	32543834	9	-	26627737	HCT116	viability after 6 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	-0.6268493510759632	[1631]	[354,61]	-4	hSpCas9	negative selection	1830407
32550872	32550895	9	-	26627737	HCT116	viability after 6 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	6.725827349361136	[0]	[44,0]	9	hSpCas9	negative selection	1830408
32550882	32550905	9	+	26627737	HCT116	viability after 6 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.35813571817804607	[998]	[30,172]	-2	hSpCas9	negative selection	1830409
32550925	32550948	9	-	26627737	HCT116	viability after 6 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.49915561749833465	[589]	[94,150]	2	hSpCas9	negative selection	1830410
32542097	32542120	9	-	26627737	HCT116	viability after 8 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.7182609346412137	[171]	[143,120,201]	6	hSpCas9	negative selection	1912720
32543374	32543397	9	+	26627737	HCT116	viability after 8 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	0.6737919783921857	[81]	[119,16,79]	6	hSpCas9	negative selection	1912721
32543811	32543834	9	-	26627737	HCT116	viability after 8 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	-0.021397488088644057	[717]	[348,453,365]	0	hSpCas9	negative selection	1912722
32550872	32550895	9	-	26627737	HCT116	viability after 8 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-1.1852099424424969	[55]	[25,6,7]	-9	hSpCas9	negative selection	1912723
32550882	32550905	9	+	26627737	HCT116	viability after 8 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	0.49356250210394087	[400]	[373,297,262]	5	hSpCas9	negative selection	1912724
32550925	32550948	9	-	26627737	HCT116	viability after 8 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.3335925960388082	[305]	[251,161,223]	3	hSpCas9	negative selection	1912725
32542097	32542120	9	-	26627737	HCT116	viability after 9 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	-2.2393789414586656	[678]	[67,14]	-9	hSpCas9	negative selection	1995035
32543374	32543397	9	+	26627737	HCT116	viability after 9 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	-0.6050811429174314	[174]	[61,5]	-4	hSpCas9	negative selection	1995036
32543811	32543834	9	-	26627737	HCT116	viability after 9 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	-0.405847348645886	[1631]	[405,267]	-3	hSpCas9	negative selection	1995037
32550872	32550895	9	-	26627737	HCT116	viability after 9 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	4.800571916422808	[0]	[7,6]	9	hSpCas9	negative selection	1995038
32550882	32550905	9	+	26627737	HCT116	viability after 9 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	0.5295661195115938	[998]	[374,392]	4	hSpCas9	negative selection	1995039
32550925	32550948	9	-	26627737	HCT116	viability after 9 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.6592717902619409	[589]	[388,137]	5	hSpCas9	negative selection	1995040
32542097	32542120	9	-	26627737	HCT116	viability after 12 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.647360044437412	[171]	[141,153,128]	6	hSpCas9	negative selection	2077350
32543374	32543397	9	+	26627737	HCT116	viability after 12 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	0.48125404815363715	[81]	[67,27,82]	5	hSpCas9	negative selection	2077351
32543811	32543834	9	-	26627737	HCT116	viability after 12 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.13719960336434078	[717]	[269,387,598]	1	hSpCas9	negative selection	2077352
32550872	32550895	9	-	26627737	HCT116	viability after 12 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-0.7350320328622804	[55]	[27,11,11]	-7	hSpCas9	negative selection	2077353
32550882	32550905	9	+	26627737	HCT116	viability after 12 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	0.44961923924322583	[400]	[232,237,395]	4	hSpCas9	negative selection	2077354
32550925	32550948	9	-	26627737	HCT116	viability after 12 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.18500780736815658	[305]	[206,210,128]	2	hSpCas9	negative selection	2077355
32542097	32542120	9	-	26627737	HCT116	viability after 15 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.9647555402040778	[171]	[151,194,225]	7	hSpCas9	negative selection	2159665
32543374	32543397	9	+	26627737	HCT116	viability after 15 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	1.2412105187153148	[81]	[199,52,91]	8	hSpCas9	negative selection	2159666
32543811	32543834	9	-	26627737	HCT116	viability after 15 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	-0.09734219345692163	[717]	[346,365,437]	-1	hSpCas9	negative selection	2159667
32550872	32550895	9	-	26627737	HCT116	viability after 15 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-0.7515752256207691	[55]	[25,0,30]	-6	hSpCas9	negative selection	2159668
32550882	32550905	9	+	26627737	HCT116	viability after 15 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	0.520821986629987	[400]	[320,329,338]	5	hSpCas9	negative selection	2159669
32550925	32550948	9	-	26627737	HCT116	viability after 15 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.43207425697011625	[305]	[173,324,204]	4	hSpCas9	negative selection	2159670
32542097	32542120	9	-	26627737	HCT116	viability after 18 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.5260343794958181	[171]	[108,125,123]	4	hSpCas9	negative selection	2241980
32543374	32543397	9	+	26627737	HCT116	viability after 18 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	0.10323898250052044	[81]	[73,18,35]	0	hSpCas9	negative selection	2241981
32543811	32543834	9	-	26627737	HCT116	viability after 18 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.5425904815441738	[717]	[548,374,605]	4	hSpCas9	negative selection	2241982
32550872	32550895	9	-	26627737	HCT116	viability after 18 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-2.1200285812338118	[55]	[3,12,0]	-9	hSpCas9	negative selection	2241983
32550882	32550905	9	+	26627737	HCT116	viability after 18 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	0.007813918622526672	[400]	[161,231,187]	0	hSpCas9	negative selection	2241984
32550925	32550948	9	-	26627737	HCT116	viability after 18 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.8685820252982855	[305]	[223,368,207]	7	hSpCas9	negative selection	2241985
32543983	32544006	9	+	24336569	HL60	viability	CGGTAGCGAAATCGTCGATCAGG	TOPORS	ENSG00000197579	0.21376390498795755	[468]	[1150]	2	hSpCas9	negative selection	2303009
32544017	32544040	9	+	24336569	HL60	viability	AACCATTATACGAAGGCCTTAGG	TOPORS	ENSG00000197579	0.7593877334167948	[595]	[2134]	6	hSpCas9	negative selection	2303010
32544033	32544056	9	-	24336569	HL60	viability	ACTTCAAGGAGTATGTCCTAAGG	TOPORS	ENSG00000197579	0.07065357881684031	[1258]	[2797]	0	hSpCas9	negative selection	2303011
32544047	32544070	9	-	24336569	HL60	viability	GAGGGCAGAAGATGACTTCAAGG	TOPORS	ENSG00000197579	0.29691084553308356	[1623]	[4221]	3	hSpCas9	negative selection	2303012
32544056	32544079	9	+	24336569	HL60	viability	CATCTTCTGCCCTCACAGAATGG	TOPORS	ENSG00000197579	1.4936747543400115	[613]	[3658]	8	hSpCas9	negative selection	2303013
32544088	32544111	9	+	24336569	HL60	viability	TCAAAGGGCTGTTTACATAGTGG	TOPORS	ENSG00000197579	0.31262445908977676	[658]	[1731]	3	hSpCas9	negative selection	2303014
32544193	32544216	9	+	24336569	HL60	viability	TCAAATCTATCCAAGCATATAGG	TOPORS	ENSG00000197579	1.8445353179273272	[29]	[227]	9	hSpCas9	negative selection	2303015
32544208	32544231	9	+	24336569	HL60	viability	CATATAGGACACTTAGAATCAGG	TOPORS	ENSG00000197579	-1.8913612172489536	[425]	[242]	-9	hSpCas9	negative selection	2303016
32544259	32544282	9	+	24336569	HL60	viability	AATTTGCTAGTGCCAGCTTTAGG	TOPORS	ENSG00000197579	1.0340131167910394	[74]	[324]	7	hSpCas9	negative selection	2303017
32544305	32544328	9	-	24336569	HL60	viability	GATAATGGCATCAGCTGCTAAGG	TOPORS	ENSG00000197579	-0.18916472968460898	[423]	[786]	-2	hSpCas9	negative selection	2303018
32543983	32544006	9	+	24336569	KBM7	viability	CGGTAGCGAAATCGTCGATCAGG	TOPORS	ENSG00000197579	0.900013781731827	[311]	[1587]	7	hSpCas9	negative selection	2370186
32544017	32544040	9	+	24336569	KBM7	viability	AACCATTATACGAAGGCCTTAGG	TOPORS	ENSG00000197579	-0.23935767534447216	[759]	[1755]	-2	hSpCas9	negative selection	2370187
32544033	32544056	9	-	24336569	KBM7	viability	ACTTCAAGGAGTATGTCCTAAGG	TOPORS	ENSG00000197579	0.39315906405470885	[475]	[1704]	3	hSpCas9	negative selection	2370188
32544047	32544070	9	-	24336569	KBM7	viability	GAGGGCAGAAGATGACTTCAAGG	TOPORS	ENSG00000197579	0.11408220480859255	[1497]	[4421]	1	hSpCas9	negative selection	2370189
32544056	32544079	9	+	24336569	KBM7	viability	CATCTTCTGCCCTCACAGAATGG	TOPORS	ENSG00000197579	0.3902792632164839	[594]	[2126]	3	hSpCas9	negative selection	2370190
32544088	32544111	9	+	24336569	KBM7	viability	TCAAAGGGCTGTTTACATAGTGG	TOPORS	ENSG00000197579	-0.4385024414297204	[712]	[1434]	-4	hSpCas9	negative selection	2370191
32544193	32544216	9	+	24336569	KBM7	viability	TCAAATCTATCCAAGCATATAGG	TOPORS	ENSG00000197579	0.5779558955582549	[27]	[113]	5	hSpCas9	negative selection	2370192
32544208	32544231	9	+	24336569	KBM7	viability	CATATAGGACACTTAGAATCAGG	TOPORS	ENSG00000197579	1.3737599549444226	[131]	[932]	9	hSpCas9	negative selection	2370193
32544259	32544282	9	+	24336569	KBM7	viability	AATTTGCTAGTGCCAGCTTTAGG	TOPORS	ENSG00000197579	1.3449787235806414	[83]	[581]	9	hSpCas9	negative selection	2370194
32544305	32544328	9	-	24336569	KBM7	viability	GATAATGGCATCAGCTGCTAAGG	TOPORS	ENSG00000197579	-0.6967509490009307	[434]	[731]	-5	hSpCas9	negative selection	2370195
32548326	32548349	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCTCCATGTTGGTCAGGCTGG	TOPORS	ENSG00000197579	-2.2958931667653815	[393,165]	[8,14]	-9	dCas9-VP64	positive selection	2417421
32548326	32548349	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCTCCATGTTGGTCAGGCTGG	TOPORS	ENSG00000197579	0.6223741115754664	[126,133]	[38,89]	4	dCas9-VP64	positive selection	2512676
32544193	32544216	9	+	27260157	DLD1	viability	TCAAATCTATCCAAGCATATAGG	TOPORS	ENSG00000197579	0.733394131835719	[]	[]	8	hSpCas9	negative selection	2577890
32550772	32550795	9	+	27260157	DLD1	viability	ACCTCGGAGGATGCCGGCGCAGG	TOPORS	ENSG00000197579	0.110792761548701	[]	[]	3	hSpCas9	negative selection	2580167
32543966	32543989	9	-	27260157	DLD1	viability	CTACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	0.123549987259739	[]	[]	3	hSpCas9	negative selection	2581598
32544259	32544282	9	+	27260157	DLD1	viability	AATTTGCTAGTGCCAGCTTTAGG	TOPORS	ENSG00000197579	0.648064417496256	[]	[]	8	hSpCas9	negative selection	2587300
32544047	32544070	9	-	27260157	DLD1	viability	GAGGGCAGAAGATGACTTCAAGG	TOPORS	ENSG00000197579	0.227754712921716	[]	[]	3	hSpCas9	negative selection	2607726
32550859	32550882	9	-	27260157	DLD1	viability	AGTCGCCGGGTACGCCTTCGCGG	TOPORS	ENSG00000197579	0.817730516186692	[]	[]	9	hSpCas9	negative selection	2609302
32543983	32544006	9	+	27260157	DLD1	viability	CGGTAGCGAAATCGTCGATCAGG	TOPORS	ENSG00000197579	-0.37229169237109	[]	[]	-3	hSpCas9	negative selection	2611842
32544033	32544056	9	-	27260157	DLD1	viability	ACTTCAAGGAGTATGTCCTAAGG	TOPORS	ENSG00000197579	-0.298964332337551	[]	[]	-2	hSpCas9	negative selection	2613002
32544019	32544042	9	-	27260157	DLD1	viability	GTCCTAAGGCCTTCGTATAATGG	TOPORS	ENSG00000197579	0.308622311630907	[]	[]	4	hSpCas9	negative selection	2614708
32544088	32544111	9	+	27260157	DLD1	viability	TCAAAGGGCTGTTTACATAGTGG	TOPORS	ENSG00000197579	-0.0298770765788909	[]	[]	0	hSpCas9	negative selection	2617304
32550892	32550915	9	+	27260157	DLD1	viability	CCCTCCGAAGCGGGAGCAGGCGG	TOPORS	ENSG00000197579	0.756281277167895	[]	[]	8	hSpCas9	negative selection	2617699
32550830	32550853	9	+	27260157	DLD1	viability	CCAGAAAGCTAGGTCGGTGTCGG	TOPORS	ENSG00000197579	-0.974641568864221	[]	[]	-7	hSpCas9	negative selection	2619763
32544305	32544328	9	-	27260157	DLD1	viability	GATAATGGCATCAGCTGCTAAGG	TOPORS	ENSG00000197579	0.0455383346068857	[]	[]	3	hSpCas9	negative selection	2620894
32550885	32550908	9	-	27260157	DLD1	viability	CTCCCGCTTCGGAGGGTAGGCGG	TOPORS	ENSG00000197579	0.256172876449944	[]	[]	4	hSpCas9	negative selection	2621761
32550872	32550895	9	-	27260157	DLD1	viability	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-0.854995940451415	[]	[]	-6	hSpCas9	negative selection	2641622
32550845	32550868	9	+	27260157	DLD1	viability	GGTGTCGGCAGGATCCGCGAAGG	TOPORS	ENSG00000197579	-0.300281407367382	[]	[]	-2	hSpCas9	negative selection	2644125
32550782	32550805	9	+	27260157	DLD1	viability	ATGCCGGCGCAGGCCTGGCTGGG	TOPORS	ENSG00000197579	0.617278583169972	[]	[]	8	hSpCas9	negative selection	2644844
32544017	32544040	9	+	27260157	DLD1	viability	AACCATTATACGAAGGCCTTAGG	TOPORS	ENSG00000197579	-0.168067276838091	[]	[]	-1	hSpCas9	negative selection	2645076
32544208	32544231	9	+	27260157	DLD1	viability	CATATAGGACACTTAGAATCAGG	TOPORS	ENSG00000197579	-0.349718827404008	[]	[]	-3	hSpCas9	negative selection	2649485
32544193	32544216	9	+	27260157	HT1080	viability	TCAAATCTATCCAAGCATATAGG	TOPORS	ENSG00000197579	0.734941960658372	[]	[]	6	hSpCas9	negative selection	2654020
32550772	32550795	9	+	27260157	HT1080	viability	ACCTCGGAGGATGCCGGCGCAGG	TOPORS	ENSG00000197579	0.853247495750422	[]	[]	7	hSpCas9	negative selection	2656297
32543966	32543989	9	-	27260157	HT1080	viability	CTACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	-0.713838200373019	[]	[]	-8	hSpCas9	negative selection	2657728
32544259	32544282	9	+	27260157	HT1080	viability	AATTTGCTAGTGCCAGCTTTAGG	TOPORS	ENSG00000197579	-0.059271540503489	[]	[]	0	hSpCas9	negative selection	2663430
32544047	32544070	9	-	27260157	HT1080	viability	GAGGGCAGAAGATGACTTCAAGG	TOPORS	ENSG00000197579	0.794942263592862	[]	[]	7	hSpCas9	negative selection	2683856
32550859	32550882	9	-	27260157	HT1080	viability	AGTCGCCGGGTACGCCTTCGCGG	TOPORS	ENSG00000197579	0.0357736348668614	[]	[]	0	hSpCas9	negative selection	2685432
32543983	32544006	9	+	27260157	HT1080	viability	CGGTAGCGAAATCGTCGATCAGG	TOPORS	ENSG00000197579	-0.160141931638846	[]	[]	0	hSpCas9	negative selection	2687972
32544033	32544056	9	-	27260157	HT1080	viability	ACTTCAAGGAGTATGTCCTAAGG	TOPORS	ENSG00000197579	0.0554296222053346	[]	[]	0	hSpCas9	negative selection	2689132
32544019	32544042	9	-	27260157	HT1080	viability	GTCCTAAGGCCTTCGTATAATGG	TOPORS	ENSG00000197579	0.267654355282762	[]	[]	2	hSpCas9	negative selection	2690838
32544088	32544111	9	+	27260157	HT1080	viability	TCAAAGGGCTGTTTACATAGTGG	TOPORS	ENSG00000197579	0.0348541325894635	[]	[]	0	hSpCas9	negative selection	2693434
32550892	32550915	9	+	27260157	HT1080	viability	CCCTCCGAAGCGGGAGCAGGCGG	TOPORS	ENSG00000197579	-0.448029708379901	[]	[]	-7	hSpCas9	negative selection	2693829
32550830	32550853	9	+	27260157	HT1080	viability	CCAGAAAGCTAGGTCGGTGTCGG	TOPORS	ENSG00000197579	-0.977853039718769	[]	[]	-8	hSpCas9	negative selection	2695893
32544305	32544328	9	-	27260157	HT1080	viability	GATAATGGCATCAGCTGCTAAGG	TOPORS	ENSG00000197579	0.924399353519526	[]	[]	7	hSpCas9	negative selection	2697024
32550885	32550908	9	-	27260157	HT1080	viability	CTCCCGCTTCGGAGGGTAGGCGG	TOPORS	ENSG00000197579	0.0444403221130619	[]	[]	0	hSpCas9	negative selection	2697891
32550872	32550895	9	-	27260157	HT1080	viability	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-0.491080756760295	[]	[]	-7	hSpCas9	negative selection	2717752
32550845	32550868	9	+	27260157	HT1080	viability	GGTGTCGGCAGGATCCGCGAAGG	TOPORS	ENSG00000197579	-0.401104826694717	[]	[]	-7	hSpCas9	negative selection	2720255
32550782	32550805	9	+	27260157	HT1080	viability	ATGCCGGCGCAGGCCTGGCTGGG	TOPORS	ENSG00000197579	-0.551094954165652	[]	[]	-7	hSpCas9	negative selection	2720974
32544017	32544040	9	+	27260157	HT1080	viability	AACCATTATACGAAGGCCTTAGG	TOPORS	ENSG00000197579	0.430138177359055	[]	[]	4	hSpCas9	negative selection	2721206
32544208	32544231	9	+	27260157	HT1080	viability	CATATAGGACACTTAGAATCAGG	TOPORS	ENSG00000197579	-0.0855338536039723	[]	[]	0	hSpCas9	negative selection	2725615
32544193	32544216	9	+	27260157	MKN45	viability	TCAAATCTATCCAAGCATATAGG	TOPORS	ENSG00000197579	0.819723591667336	[]	[]	8	hSpCas9	negative selection	2730150
32550772	32550795	9	+	27260157	MKN45	viability	ACCTCGGAGGATGCCGGCGCAGG	TOPORS	ENSG00000197579	1.073259690608	[]	[]	8	hSpCas9	negative selection	2732427
32543966	32543989	9	-	27260157	MKN45	viability	CTACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	-0.111704201738123	[]	[]	0	hSpCas9	negative selection	2733858
32544259	32544282	9	+	27260157	MKN45	viability	AATTTGCTAGTGCCAGCTTTAGG	TOPORS	ENSG00000197579	0.348539185865511	[]	[]	6	hSpCas9	negative selection	2739560
32544047	32544070	9	-	27260157	MKN45	viability	GAGGGCAGAAGATGACTTCAAGG	TOPORS	ENSG00000197579	0.975520233128284	[]	[]	8	hSpCas9	negative selection	2759986
32550859	32550882	9	-	27260157	MKN45	viability	AGTCGCCGGGTACGCCTTCGCGG	TOPORS	ENSG00000197579	0.624658031090615	[]	[]	7	hSpCas9	negative selection	2761562
32543983	32544006	9	+	27260157	MKN45	viability	CGGTAGCGAAATCGTCGATCAGG	TOPORS	ENSG00000197579	-0.760404258964318	[]	[]	-7	hSpCas9	negative selection	2764102
32544033	32544056	9	-	27260157	MKN45	viability	ACTTCAAGGAGTATGTCCTAAGG	TOPORS	ENSG00000197579	-0.531853794436251	[]	[]	-6	hSpCas9	negative selection	2765262
32544019	32544042	9	-	27260157	MKN45	viability	GTCCTAAGGCCTTCGTATAATGG	TOPORS	ENSG00000197579	0.218645587128447	[]	[]	5	hSpCas9	negative selection	2766968
32544088	32544111	9	+	27260157	MKN45	viability	TCAAAGGGCTGTTTACATAGTGG	TOPORS	ENSG00000197579	0.600711120921333	[]	[]	7	hSpCas9	negative selection	2769564
32550892	32550915	9	+	27260157	MKN45	viability	CCCTCCGAAGCGGGAGCAGGCGG	TOPORS	ENSG00000197579	-0.442358362644894	[]	[]	-6	hSpCas9	negative selection	2769959
32550830	32550853	9	+	27260157	MKN45	viability	CCAGAAAGCTAGGTCGGTGTCGG	TOPORS	ENSG00000197579	-0.486209927643964	[]	[]	-6	hSpCas9	negative selection	2772023
32544305	32544328	9	-	27260157	MKN45	viability	GATAATGGCATCAGCTGCTAAGG	TOPORS	ENSG00000197579	0.318829402628999	[]	[]	5	hSpCas9	negative selection	2773154
32550885	32550908	9	-	27260157	MKN45	viability	CTCCCGCTTCGGAGGGTAGGCGG	TOPORS	ENSG00000197579	0.2276568385167	[]	[]	5	hSpCas9	negative selection	2774021
32550872	32550895	9	-	27260157	MKN45	viability	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-1.11338143639433	[]	[]	-8	hSpCas9	negative selection	2793882
32550845	32550868	9	+	27260157	MKN45	viability	GGTGTCGGCAGGATCCGCGAAGG	TOPORS	ENSG00000197579	0.282411193972531	[]	[]	5	hSpCas9	negative selection	2796385
32550782	32550805	9	+	27260157	MKN45	viability	ATGCCGGCGCAGGCCTGGCTGGG	TOPORS	ENSG00000197579	1.18214428503189	[]	[]	8	hSpCas9	negative selection	2797104
32544017	32544040	9	+	27260157	MKN45	viability	AACCATTATACGAAGGCCTTAGG	TOPORS	ENSG00000197579	0.418115902038633	[]	[]	6	hSpCas9	negative selection	2797336
32544208	32544231	9	+	27260157	MKN45	viability	CATATAGGACACTTAGAATCAGG	TOPORS	ENSG00000197579	-0.155400471797198	[]	[]	0	hSpCas9	negative selection	2801745
32544193	32544216	9	+	27260157	RKO	viability	TCAAATCTATCCAAGCATATAGG	TOPORS	ENSG00000197579	0.960809463436721	[]	[]	8	hSpCas9	negative selection	2806280
32550772	32550795	9	+	27260157	RKO	viability	ACCTCGGAGGATGCCGGCGCAGG	TOPORS	ENSG00000197579	0.415840409052709	[]	[]	2	hSpCas9	negative selection	2808557
32543966	32543989	9	-	27260157	RKO	viability	CTACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	-0.481224643721757	[]	[]	-6	hSpCas9	negative selection	2809988
32544259	32544282	9	+	27260157	RKO	viability	AATTTGCTAGTGCCAGCTTTAGG	TOPORS	ENSG00000197579	0.416430405421719	[]	[]	2	hSpCas9	negative selection	2815690
32544047	32544070	9	-	27260157	RKO	viability	GAGGGCAGAAGATGACTTCAAGG	TOPORS	ENSG00000197579	0.684313883142521	[]	[]	7	hSpCas9	negative selection	2836116
32550859	32550882	9	-	27260157	RKO	viability	AGTCGCCGGGTACGCCTTCGCGG	TOPORS	ENSG00000197579	0.501490551455551	[]	[]	2	hSpCas9	negative selection	2837692
32543983	32544006	9	+	27260157	RKO	viability	CGGTAGCGAAATCGTCGATCAGG	TOPORS	ENSG00000197579	-0.778661852291448	[]	[]	-7	hSpCas9	negative selection	2840232
32544033	32544056	9	-	27260157	RKO	viability	ACTTCAAGGAGTATGTCCTAAGG	TOPORS	ENSG00000197579	0.419386474035812	[]	[]	2	hSpCas9	negative selection	2841392
32544019	32544042	9	-	27260157	RKO	viability	GTCCTAAGGCCTTCGTATAATGG	TOPORS	ENSG00000197579	0.187910844319119	[]	[]	1	hSpCas9	negative selection	2843098
32544088	32544111	9	+	27260157	RKO	viability	TCAAAGGGCTGTTTACATAGTGG	TOPORS	ENSG00000197579	-0.181014130962261	[]	[]	-1	hSpCas9	negative selection	2845694
32550892	32550915	9	+	27260157	RKO	viability	CCCTCCGAAGCGGGAGCAGGCGG	TOPORS	ENSG00000197579	-0.0704954647716218	[]	[]	0	hSpCas9	negative selection	2846089
32550830	32550853	9	+	27260157	RKO	viability	CCAGAAAGCTAGGTCGGTGTCGG	TOPORS	ENSG00000197579	-0.505699039634943	[]	[]	-6	hSpCas9	negative selection	2848153
32544305	32544328	9	-	27260157	RKO	viability	GATAATGGCATCAGCTGCTAAGG	TOPORS	ENSG00000197579	0.400277147010467	[]	[]	2	hSpCas9	negative selection	2849284
32550885	32550908	9	-	27260157	RKO	viability	CTCCCGCTTCGGAGGGTAGGCGG	TOPORS	ENSG00000197579	-0.455415240084121	[]	[]	-6	hSpCas9	negative selection	2850151
32550872	32550895	9	-	27260157	RKO	viability	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-0.0728578171499771	[]	[]	0	hSpCas9	negative selection	2870012
32550845	32550868	9	+	27260157	RKO	viability	GGTGTCGGCAGGATCCGCGAAGG	TOPORS	ENSG00000197579	0.072258753685523	[]	[]	0	hSpCas9	negative selection	2872515
32550782	32550805	9	+	27260157	RKO	viability	ATGCCGGCGCAGGCCTGGCTGGG	TOPORS	ENSG00000197579	0.329025552819977	[]	[]	1	hSpCas9	negative selection	2873234
32544017	32544040	9	+	27260157	RKO	viability	AACCATTATACGAAGGCCTTAGG	TOPORS	ENSG00000197579	0.358880993892273	[]	[]	2	hSpCas9	negative selection	2873466
32544208	32544231	9	+	27260157	RKO	viability	CATATAGGACACTTAGAATCAGG	TOPORS	ENSG00000197579	-0.428616907422856	[]	[]	-6	hSpCas9	negative selection	2877875
32544193	32544216	9	+	27260157	SF268	viability	TCAAATCTATCCAAGCATATAGG	TOPORS	ENSG00000197579	0.378322363567851	[]	[]	4	hSpCas9	negative selection	2882410
32550772	32550795	9	+	27260157	SF268	viability	ACCTCGGAGGATGCCGGCGCAGG	TOPORS	ENSG00000197579	0.0578585472181692	[]	[]	0	hSpCas9	negative selection	2884687
32543966	32543989	9	-	27260157	SF268	viability	CTACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	-0.508123845256979	[]	[]	-4	hSpCas9	negative selection	2886118
32544259	32544282	9	+	27260157	SF268	viability	AATTTGCTAGTGCCAGCTTTAGG	TOPORS	ENSG00000197579	-0.278505792592703	[]	[]	-2	hSpCas9	negative selection	2891820
32544047	32544070	9	-	27260157	SF268	viability	GAGGGCAGAAGATGACTTCAAGG	TOPORS	ENSG00000197579	0.169691108573454	[]	[]	0	hSpCas9	negative selection	2912246
32550859	32550882	9	-	27260157	SF268	viability	AGTCGCCGGGTACGCCTTCGCGG	TOPORS	ENSG00000197579	0.342379687688406	[]	[]	4	hSpCas9	negative selection	2913822
32543983	32544006	9	+	27260157	SF268	viability	CGGTAGCGAAATCGTCGATCAGG	TOPORS	ENSG00000197579	-0.762788448025603	[]	[]	-6	hSpCas9	negative selection	2916362
32544033	32544056	9	-	27260157	SF268	viability	ACTTCAAGGAGTATGTCCTAAGG	TOPORS	ENSG00000197579	-0.0647945503971179	[]	[]	0	hSpCas9	negative selection	2917522
32544019	32544042	9	-	27260157	SF268	viability	GTCCTAAGGCCTTCGTATAATGG	TOPORS	ENSG00000197579	0.098867269592985	[]	[]	0	hSpCas9	negative selection	2919228
32544088	32544111	9	+	27260157	SF268	viability	TCAAAGGGCTGTTTACATAGTGG	TOPORS	ENSG00000197579	-0.691425750703101	[]	[]	-5	hSpCas9	negative selection	2921824
32550892	32550915	9	+	27260157	SF268	viability	CCCTCCGAAGCGGGAGCAGGCGG	TOPORS	ENSG00000197579	-0.157570753082699	[]	[]	-1	hSpCas9	negative selection	2922219
32550830	32550853	9	+	27260157	SF268	viability	CCAGAAAGCTAGGTCGGTGTCGG	TOPORS	ENSG00000197579	-1.35277393282037	[]	[]	-7	hSpCas9	negative selection	2924283
32544305	32544328	9	-	27260157	SF268	viability	GATAATGGCATCAGCTGCTAAGG	TOPORS	ENSG00000197579	0.414977673260306	[]	[]	4	hSpCas9	negative selection	2925414
32550885	32550908	9	-	27260157	SF268	viability	CTCCCGCTTCGGAGGGTAGGCGG	TOPORS	ENSG00000197579	-0.851665187450698	[]	[]	-6	hSpCas9	negative selection	2926281
32550872	32550895	9	-	27260157	SF268	viability	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-0.943869519317938	[]	[]	-6	hSpCas9	negative selection	2946142
32550845	32550868	9	+	27260157	SF268	viability	GGTGTCGGCAGGATCCGCGAAGG	TOPORS	ENSG00000197579	-0.353579151784842	[]	[]	-3	hSpCas9	negative selection	2948645
32550782	32550805	9	+	27260157	SF268	viability	ATGCCGGCGCAGGCCTGGCTGGG	TOPORS	ENSG00000197579	-0.596446248878962	[]	[]	-4	hSpCas9	negative selection	2949364
32544017	32544040	9	+	27260157	SF268	viability	AACCATTATACGAAGGCCTTAGG	TOPORS	ENSG00000197579	-0.187482776204046	[]	[]	-1	hSpCas9	negative selection	2949596
32544208	32544231	9	+	27260157	SF268	viability	CATATAGGACACTTAGAATCAGG	TOPORS	ENSG00000197579	-0.840315279014859	[]	[]	-6	hSpCas9	negative selection	2954005
32543966	32543989	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	-0.14802775752392666	[3,3]	[2,2]	-2	hSpCas9	positive selection	3028614
32543822	32543845	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.179325644620362	[3,3]	[2,4]	4	hSpCas9	positive selection	3028615
32543986	32544009	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.14831536287339392	[3,4]	[3,4]	3	hSpCas9	positive selection	3028616
32543349	32543372	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATGACTGAAGAATCAGAATGG	TOPORS	ENSG00000197579	-0.5375798134438643	[2,2]	[0,1]	-7	hSpCas9	positive selection	3028617
32543966	32543989	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	0.34331439864186397	[3,3]	[3,3]	6	hSpCas9	positive selection	3096472
32543822	32543845	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.38016369834614827	[3,3]	[2,4]	6	hSpCas9	positive selection	3096473
32543986	32544009	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	-0.12891527426933055	[3,3]	[3,1]	-2	hSpCas9	positive selection	3096474
32543349	32543372	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATGACTGAAGAATCAGAATGG	TOPORS	ENSG00000197579	-0.3601441266916854	[2,2]	[2,0]	-5	hSpCas9	positive selection	3096475
32543728	32543751		-	24336571	A375	resistance to PLX after 7 days	AGACGAACTCTTTATCGTGCTGG	TOPORS	ENSG00000197579	-0.0028645305271252086	[18,26]	[23,20]	0	hSpCas9	positive selection	3152067
32550854	32550877		+	24336571	A375	resistance to PLX after 7 days	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	-0.24023863549983748	[17,17]	[14,14]	-7	hSpCas9	positive selection	3152068
32543967	32543990		-	24336571	A375	resistance to PLX after 7 days	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.024581200737765707	[22,24]	[21,25]	0	hSpCas9	positive selection	3152069
32550926	32550949		-	24336571	A375	resistance to PLX after 7 days	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.1681776088870106	[4,5]	[5,5]	5	hSpCas9	positive selection	3152071
32543728	32543751		-	24336571	A375	resistance to PLX after 14 days	AGACGAACTCTTTATCGTGCTGG	TOPORS	ENSG00000197579	-0.493343695974638	[23,24]	[8,6]	-6	hSpCas9	positive selection	3209860
32550854	32550877		+	24336571	A375	resistance to PLX after 14 days	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	-0.08098545402800805	[15,19]	[5,9]	-1	hSpCas9	positive selection	3209861
32543967	32543990		-	24336571	A375	resistance to PLX after 14 days	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.5112201670168772	[26,23]	[6,8]	-6	hSpCas9	positive selection	3209862
32550926	32550949		-	24336571	A375	resistance to PLX after 14 days	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.52397952125935	[3,6]	[2,3]	5	hSpCas9	positive selection	3209864
32543728	32543751		-	24336571	A375	viability after 7 days	AGACGAACTCTTTATCGTGCTGG	TOPORS	ENSG00000197579	-0.18137316820034477	[26]	[18,26]	-3	hSpCas9	negative selection	3267653
32550854	32550877		+	24336571	A375	viability after 7 days	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.5168611292726755	[12]	[17,17]	7	hSpCas9	negative selection	3267654
32543967	32543990		-	24336571	A375	viability after 7 days	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.768762153331922	[42]	[22,24]	-8	hSpCas9	negative selection	3267655
32550926	32550949		-	24336571	A375	viability after 7 days	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	-0.4276791406945524	[7]	[4,5]	-6	hSpCas9	negative selection	3267657
32543728	32543751		-	24336571	A375	viability after 14 days	AGACGAACTCTTTATCGTGCTGG	TOPORS	ENSG00000197579	-0.057921798520924495	[26]	[23,24]	0	hSpCas9	negative selection	3325446
32550854	32550877		+	24336571	A375	viability after 14 days	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.5466826611580059	[12]	[15,19]	7	hSpCas9	negative selection	3325447
32543967	32543990		-	24336571	A375	viability after 14 days	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.6498116822464666	[42]	[26,23]	-7	hSpCas9	negative selection	3325448
32550926	32550949		-	24336571	A375	viability after 14 days	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	-0.449790830475149	[7]	[3,6]	-5	hSpCas9	negative selection	3325450
32542167	32542190	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.5708256842626168	[102,102]	[0,0]	3	hSpCas9	positive selection	3398573
32550830	32550853	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	-0.537089654904271	[221,221]	[0,0]	-4	hSpCas9	positive selection	3398574
32543788	32543811	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	-0.3049162127752376	[188,188]	[0,0]	-2	hSpCas9	positive selection	3398575
32543966	32543989	9	-	26780180	HT29	viability (Avana library 4 designs)	CTACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	0.828276277957627	[]	[]	3	hSpCas9	negative selection	3467425
32543821	32543844	9	+	26780180	HT29	viability (Avana library 4 designs)	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.563436803623548	[]	[]	2	hSpCas9	negative selection	3467426
32543985	32544008	9	+	26780180	HT29	viability (Avana library 4 designs)	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.784665026626965	[]	[]	3	hSpCas9	negative selection	3467427
32543348	32543371	9	+	26780180	HT29	viability (Avana library 4 designs)	TTATGACTGAAGAATCAGAATGG	TOPORS	ENSG00000197579	1.16421590728004	[]	[]	4	hSpCas9	negative selection	3467428
32543985	32544008	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	1.61573952788416	[]	[]	2	hSpCas9	negative selection	3571576
32543966	32543989	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	-3.41441801866829	[]	[]	-4	hSpCas9	negative selection	3571577
32543821	32543844	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	-4.79305640654082	[]	[]	-5	hSpCas9	negative selection	3571578
32543348	32543371	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATGACTGAAGAATCAGAATGG	TOPORS	ENSG00000197579	-14.6915494715892	[]	[]	-9	hSpCas9	negative selection	3571579
32543963	32543986	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCCCTTGTCAGAGTTGTACGG	TOPORS	ENSG00000197579	3.77663694096958	[]	[]	6	hSpCas9	negative selection	3571580
32543935	32543958	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCTGTGTATTCACCTAGTGG	TOPORS	ENSG00000197579	-0.830993319951834	[]	[]	-1	hSpCas9	negative selection	3571581
32543985	32544008	9	+	26780180	A375	viability (Avana lentiGuide)	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	5.26017616185146	[]	[]	5	hSpCas9	negative selection	3680235
32543966	32543989	9	-	26780180	A375	viability (Avana lentiGuide)	CTACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	-0.187084835044394	[]	[]	0	hSpCas9	negative selection	3680236
32543821	32543844	9	+	26780180	A375	viability (Avana lentiGuide)	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	1.85540666799885	[]	[]	2	hSpCas9	negative selection	3680237
32543348	32543371	9	+	26780180	A375	viability (Avana lentiGuide)	TTATGACTGAAGAATCAGAATGG	TOPORS	ENSG00000197579	-2.87989825110254	[]	[]	-5	hSpCas9	negative selection	3680238
32543963	32543986	9	+	26780180	A375	viability (Avana lentiGuide)	GTTCCCTTGTCAGAGTTGTACGG	TOPORS	ENSG00000197579	-5.8303001177962	[]	[]	-8	hSpCas9	negative selection	3680239
32543935	32543958	9	-	26780180	A375	viability (Avana lentiGuide)	GCTTCTGTGTATTCACCTAGTGG	TOPORS	ENSG00000197579	0.112790873462237	[]	[]	0	hSpCas9	negative selection	3680240
32543985	32544008	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.10181280410963314	[6]	[6,6]	2	hSpCas9	positive selection	3788842
32543966	32543989	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	-0.414241501817351	[5]	[4,2]	-6	hSpCas9	positive selection	3788843
32543821	32543844	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	-0.631580614836464	[4]	[4,1]	-7	hSpCas9	positive selection	3788844
32543348	32543371	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATGACTGAAGAATCAGAATGG	TOPORS	ENSG00000197579	-1.5933829070484449	[6]	[1,1]	-9	hSpCas9	positive selection	3788845
32543963	32543986	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCCCTTGTCAGAGTTGTACGG	TOPORS	ENSG00000197579	0.32652851073973	[5]	[6,6]	8	hSpCas9	positive selection	3788846
32543935	32543958	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCTGTGTATTCACCTAGTGG	TOPORS	ENSG00000197579	0.14236343294001175	[5]	[5,5]	4	hSpCas9	positive selection	3788847
32543985	32544008	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	-0.02321168468095891	[6]	[6,4]	0	hSpCas9	positive selection	3897449
32543966	32543989	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	-0.17475971483336003	[5]	[4,3]	-2	hSpCas9	positive selection	3897450
32543821	32543844	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.17999234406032696	[5]	[4,5]	4	hSpCas9	positive selection	3897451
32543348	32543371	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATGACTGAAGAATCAGAATGG	TOPORS	ENSG00000197579	-0.0861175033639574	[4]	[3,2]	-1	hSpCas9	positive selection	3897452
32543963	32543986	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCCCTTGTCAGAGTTGTACGG	TOPORS	ENSG00000197579	0.461512447951992	[5]	[6,6]	9	hSpCas9	positive selection	3897453
32543935	32543958	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCTGTGTATTCACCTAGTGG	TOPORS	ENSG00000197579	0.2100809199537071	[5]	[6,4]	5	hSpCas9	positive selection	3897454
32550854	32550877	9	+	26780180	A375	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.765645646751054	[]	[]	3	hSpCas9	negative selection	4006821
32550830	32550853	9	-	26780180	A375	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	1.14978337695934	[]	[]	6	hSpCas9	negative selection	4006822
32542167	32542190	9	-	26780180	A375	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.973021140014334	[]	[]	4	hSpCas9	negative selection	4006823
32543788	32543811	9	+	26780180	A375	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.68811169778232	[]	[]	2	hSpCas9	negative selection	4006824
32543967	32543990	9	-	26780180	A375	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	1.45201222447989	[]	[]	8	hSpCas9	negative selection	4006825
32550926	32550949	9	-	26780180	A375	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.872237088550558	[]	[]	3	hSpCas9	negative selection	4006826
32550854	32550877	9	+	26780180	HT29	viability (GeCKOv2 library)	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.484673189143587	[]	[]	1	hSpCas9	negative selection	4114787
32550830	32550853	9	-	26780180	HT29	viability (GeCKOv2 library)	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.793275009974455	[]	[]	3	hSpCas9	negative selection	4114788
32542167	32542190	9	-	26780180	HT29	viability (GeCKOv2 library)	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	1.41468012257268	[]	[]	7	hSpCas9	negative selection	4114789
32543788	32543811	9	+	26780180	HT29	viability (GeCKOv2 library)	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	1.54947812680084	[]	[]	7	hSpCas9	negative selection	4114790
32543967	32543990	9	-	26780180	HT29	viability (GeCKOv2 library)	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.501834060233033	[]	[]	1	hSpCas9	negative selection	4114791
32550926	32550949	9	-	26780180	HT29	viability (GeCKOv2 library)	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.581757397987544	[]	[]	2	hSpCas9	negative selection	4114792
32543728	32543751	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGACGAACTCTTTATCGTGCTGG	TOPORS	ENSG00000197579	0.06491521094128687	[3]	[2,2]	1	hSpCas9	positive selection	4178601
32550854	32550877	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.07762211155101426	[3]	[2,2]	2	hSpCas9	positive selection	4178602
32543967	32543990	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.046649128235271675	[4]	[2,2]	-1	hSpCas9	positive selection	4178603
32550926	32550949	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.13011642924746553	[2]	[2,1]	3	hSpCas9	positive selection	4178605
32543728	32543751	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGACGAACTCTTTATCGTGCTGG	TOPORS	ENSG00000197579	-0.49617024120871467	[4]	[0,0,3,0]	-7	hSpCas9	positive selection	4242623
32550854	32550877	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.015201867411863412	[2]	[1,1,1,0]	0	hSpCas9	positive selection	4242624
32543967	32543990	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	1.2005452413393445	[5]	[5,4,4,5]	8	hSpCas9	positive selection	4242625
32550926	32550949	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	-0.6095302356930339	[3]	[0,0,0,0]	-8	hSpCas9	positive selection	4242627
32550926	32550949	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	-0.15557062602364358	[1]	[1,0]	-3	hSpCas9	positive selection	4304633
32550854	32550877	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.1390160580979166	[3]	[2,2]	3	hSpCas9	positive selection	4304634
32543967	32543990	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.10294218184546233	[3]	[3,2]	2	hSpCas9	positive selection	4304635
32542167	32542190	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.28010484936128777	[2]	[1,0]	-5	hSpCas9	positive selection	4368882
32550830	32550853	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.3215342484530191	[3]	[3,3]	6	hSpCas9	positive selection	4368883
32543788	32543811	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	-0.008463264369143228	[2]	[2,1]	0	hSpCas9	positive selection	4368884
32543429	32543451	9	-	27760321	OCIAML3	viability	GCCCGATCTCCTTTTAACATGG	TOPORS	ENSG00000197579	1.1742551864828839	[397,316]	[634,616]	9	hSpCas9	negative selection	4449282
32543611	32543633	9	+	27760321	OCIAML3	viability	GTAAGTTCACGTTTTAACCAGG	TOPORS	ENSG00000197579	-0.0697549812370517	[62,74]	[21,90]	-1	hSpCas9	negative selection	4449283
32543888	32543910	9	+	27760321	OCIAML3	viability	ACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.4996602362689483	[867,595]	[718,904]	6	hSpCas9	negative selection	4449284
32543966	32543988	9	-	27760321	OCIAML3	viability	TACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	0.9768989386580637	[189,134]	[197,311]	9	hSpCas9	negative selection	4449285
32543985	32544007	9	+	27760321	OCIAML3	viability	GTAGCGAAATCGTCGATCAGGG	TOPORS	ENSG00000197579	-1.4950865793247428	[403,348]	[78,136]	-8	hSpCas9	negative selection	4449286
32543429	32543451	9	-	27760321	OCIAML2	viability	GCCCGATCTCCTTTTAACATGG	TOPORS	ENSG00000197579	0.5604966096205604	[397,316]	[410,440]	7	hSpCas9	negative selection	4532745
32543611	32543633	9	+	27760321	OCIAML2	viability	GTAAGTTCACGTTTTAACCAGG	TOPORS	ENSG00000197579	-0.754490078550659	[62,74]	[32,33]	-7	hSpCas9	negative selection	4532746
32543888	32543910	9	+	27760321	OCIAML2	viability	ACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.1459134531080457	[867,595]	[513,822]	2	hSpCas9	negative selection	4532747
32543966	32543988	9	-	27760321	OCIAML2	viability	TACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	0.02224486778729995	[189,134]	[119,147]	0	hSpCas9	negative selection	4532748
32543985	32544007	9	+	27760321	OCIAML2	viability	GTAGCGAAATCGTCGATCAGGG	TOPORS	ENSG00000197579	-0.11997592266481222	[403,348]	[225,349]	-1	hSpCas9	negative selection	4532749
32543429	32543451	9	-	27760321	MV411	viability	GCCCGATCTCCTTTTAACATGG	TOPORS	ENSG00000197579	0.8853924385462444	[397,316]	[644,114]	6	hSpCas9	negative selection	4616208
32543611	32543633	9	+	27760321	MV411	viability	GTAAGTTCACGTTTTAACCAGG	TOPORS	ENSG00000197579	-4.146028575758304	[62,74]	[0,4]	-9	hSpCas9	negative selection	4616209
32543888	32543910	9	+	27760321	MV411	viability	ACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	-0.5319095994062664	[867,595]	[204,517]	-4	hSpCas9	negative selection	4616210
32543966	32543988	9	-	27760321	MV411	viability	TACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	1.233313908110556	[189,134]	[296,177]	8	hSpCas9	negative selection	4616211
32543985	32544007	9	+	27760321	MV411	viability	GTAGCGAAATCGTCGATCAGGG	TOPORS	ENSG00000197579	-1.9049677091713908	[403,348]	[20,133]	-8	hSpCas9	negative selection	4616212
32543429	32543451	9	-	27760321	HL60	viability	GCCCGATCTCCTTTTAACATGG	TOPORS	ENSG00000197579	0.6148820954990963	[397,316]	[362,530]	7	hSpCas9	negative selection	4699671
32543611	32543633	9	+	27760321	HL60	viability	GTAAGTTCACGTTTTAACCAGG	TOPORS	ENSG00000197579	0.09738007576660346	[62,74]	[41,80]	1	hSpCas9	negative selection	4699672
32543888	32543910	9	+	27760321	HL60	viability	ACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.3621015594667193	[867,595]	[654,869]	4	hSpCas9	negative selection	4699673
32543966	32543988	9	-	27760321	HL60	viability	TACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	-0.08900382743625745	[189,134]	[72,176]	-1	hSpCas9	negative selection	4699674
32543985	32544007	9	+	27760321	HL60	viability	GTAGCGAAATCGTCGATCAGGG	TOPORS	ENSG00000197579	-0.6720498523219994	[403,348]	[175,209]	-6	hSpCas9	negative selection	4699675
32543429	32543451	9	-	27760321	HT1080	viability	GCCCGATCTCCTTTTAACATGG	TOPORS	ENSG00000197579	1.821805017880079	[316,247]	[237,572]	8	hSpCas9	negative selection	4783134
32543611	32543633	9	+	27760321	HT1080	viability	GTAAGTTCACGTTTTAACCAGG	TOPORS	ENSG00000197579	-1.2151987269814613	[74,58]	[0,22]	-5	hSpCas9	negative selection	4783135
32543888	32543910	9	+	27760321	HT1080	viability	ACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	1.8333577786078152	[595,464]	[354,1188]	8	hSpCas9	negative selection	4783136
32543966	32543988	9	-	27760321	HT1080	viability	TACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	1.9366390423992228	[134,105]	[232,129]	8	hSpCas9	negative selection	4783137
32543985	32544007	9	+	27760321	HT1080	viability	GTAGCGAAATCGTCGATCAGGG	TOPORS	ENSG00000197579	0.16618264780545455	[348,272]	[181,91]	0	hSpCas9	negative selection	4783138
32543429	32543451	9	-	27760321	HT29	viability after 7 days	GCCCGATCTCCTTTTAACATGG	TOPORS	ENSG00000197579	0.8740521016745653	[316,247]	[623,653,710]	9	hSpCas9	negative selection	4866597
32543611	32543633	9	+	27760321	HT29	viability after 7 days	GTAAGTTCACGTTTTAACCAGG	TOPORS	ENSG00000197579	-1.4789458091152974	[74,58]	[55,31,8]	-9	hSpCas9	negative selection	4866598
32543888	32543910	9	+	27760321	HT29	viability after 7 days	ACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.7294736246585074	[595,464]	[1124,1256,1011]	9	hSpCas9	negative selection	4866599
32543966	32543988	9	-	27760321	HT29	viability after 7 days	TACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	-0.29011435726141177	[134,105]	[246,79,71]	-4	hSpCas9	negative selection	4866600
32543985	32544007	9	+	27760321	HT29	viability after 7 days	GTAGCGAAATCGTCGATCAGGG	TOPORS	ENSG00000197579	0.05575963618308083	[348,272]	[470,516,270]	0	hSpCas9	negative selection	4866601
32543429	32543451	9	-	27760321	HT29	viability after 25 days	GCCCGATCTCCTTTTAACATGG	TOPORS	ENSG00000197579	0.9247284375011433	[316,247]	[606,603,628]	9	hSpCas9	negative selection	4950060
32543611	32543633	9	+	27760321	HT29	viability after 25 days	GTAAGTTCACGTTTTAACCAGG	TOPORS	ENSG00000197579	-0.09086780208764145	[74,58]	[113,35,61]	-1	hSpCas9	negative selection	4950061
32543888	32543910	9	+	27760321	HT29	viability after 25 days	ACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.6069444733011715	[595,464]	[853,831,1105]	6	hSpCas9	negative selection	4950062
32543966	32543988	9	-	27760321	HT29	viability after 25 days	TACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	0.37054511519395517	[134,105]	[93,183,270]	4	hSpCas9	negative selection	4950063
32543985	32544007	9	+	27760321	HT29	viability after 25 days	GTAGCGAAATCGTCGATCAGGG	TOPORS	ENSG00000197579	-0.023907154517975704	[348,272]	[264,487,294]	0	hSpCas9	negative selection	4950064
32543429	32543451	9	-	27760321	HT29	viability after 22 days	GCCCGATCTCCTTTTAACATGG	TOPORS	ENSG00000197579	0.8784418886300764	[316,247]	[630,629,538]	8	hSpCas9	negative selection	5033523
32543611	32543633	9	+	27760321	HT29	viability after 22 days	GTAAGTTCACGTTTTAACCAGG	TOPORS	ENSG00000197579	0.3298249793522219	[74,58]	[80,75,135]	3	hSpCas9	negative selection	5033524
32543888	32543910	9	+	27760321	HT29	viability after 22 days	ACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.5984137877172131	[595,464]	[1082,911,784]	6	hSpCas9	negative selection	5033525
32543966	32543988	9	-	27760321	HT29	viability after 22 days	TACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	0.6004700180934923	[134,105]	[157,193,283]	6	hSpCas9	negative selection	5033526
32543985	32544007	9	+	27760321	HT29	viability after 22 days	GTAGCGAAATCGTCGATCAGGG	TOPORS	ENSG00000197579	-0.007210208339283902	[348,272]	[230,464,380]	0	hSpCas9	negative selection	5033527
32543429	32543451	9	-	27760321	HT29	viability after 19 days	GCCCGATCTCCTTTTAACATGG	TOPORS	ENSG00000197579	1.269248392664859	[316,247]	[553,803,947]	9	hSpCas9	negative selection	5116986
32543611	32543633	9	+	27760321	HT29	viability after 19 days	GTAAGTTCACGTTTTAACCAGG	TOPORS	ENSG00000197579	-0.10647769578584443	[74,58]	[211,16,1]	-1	hSpCas9	negative selection	5116987
32543888	32543910	9	+	27760321	HT29	viability after 19 days	ACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.6219895914376252	[595,464]	[1308,1164,386]	6	hSpCas9	negative selection	5116988
32543966	32543988	9	-	27760321	HT29	viability after 19 days	TACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	0.8771916796608047	[134,105]	[132,174,431]	8	hSpCas9	negative selection	5116989
32543985	32544007	9	+	27760321	HT29	viability after 19 days	GTAGCGAAATCGTCGATCAGGG	TOPORS	ENSG00000197579	-0.12570579177545743	[348,272]	[325,327,323]	-1	hSpCas9	negative selection	5116990
32543429	32543451	9	-	27760321	HT29	viability after 16 days	GCCCGATCTCCTTTTAACATGG	TOPORS	ENSG00000197579	0.5407246133075923	[316,247]	[675,416,307]	6	hSpCas9	negative selection	5200449
32543611	32543633	9	+	27760321	HT29	viability after 16 days	GTAAGTTCACGTTTTAACCAGG	TOPORS	ENSG00000197579	-0.256713879500285	[74,58]	[91,26,72]	-3	hSpCas9	negative selection	5200450
32543888	32543910	9	+	27760321	HT29	viability after 16 days	ACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	1.0122301611532667	[595,464]	[1166,1478,934]	9	hSpCas9	negative selection	5200451
32543966	32543988	9	-	27760321	HT29	viability after 16 days	TACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	0.3145243845342376	[134,105]	[149,146,204]	3	hSpCas9	negative selection	5200452
32543985	32544007	9	+	27760321	HT29	viability after 16 days	GTAGCGAAATCGTCGATCAGGG	TOPORS	ENSG00000197579	0.19423449029616519	[348,272]	[434,392,369]	2	hSpCas9	negative selection	5200453
32543429	32543451	9	-	27760321	HT29	viability after 13 days	GCCCGATCTCCTTTTAACATGG	TOPORS	ENSG00000197579	0.767378637155308	[316,247]	[384,592,687]	8	hSpCas9	negative selection	5283912
32543611	32543633	9	+	27760321	HT29	viability after 13 days	GTAAGTTCACGTTTTAACCAGG	TOPORS	ENSG00000197579	0.06780050517390324	[74,58]	[99,20,120]	0	hSpCas9	negative selection	5283913
32543888	32543910	9	+	27760321	HT29	viability after 13 days	ACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.48083073562236867	[595,464]	[685,881,999]	6	hSpCas9	negative selection	5283914
32543966	32543988	9	-	27760321	HT29	viability after 13 days	TACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	0.8384148623191214	[134,105]	[196,264,285]	9	hSpCas9	negative selection	5283915
32543985	32544007	9	+	27760321	HT29	viability after 13 days	GTAGCGAAATCGTCGATCAGGG	TOPORS	ENSG00000197579	0.018008114106779355	[348,272]	[522,365,215]	0	hSpCas9	negative selection	5283916
32543429	32543451	9	-	27760321	HT29	viability after 10 days	GCCCGATCTCCTTTTAACATGG	TOPORS	ENSG00000197579	0.6891720769833349	[316,247]	[405,595,701]	8	hSpCas9	negative selection	5367375
32543611	32543633	9	+	27760321	HT29	viability after 10 days	GTAAGTTCACGTTTTAACCAGG	TOPORS	ENSG00000197579	-1.1024245570812643	[74,58]	[59,50,6]	-8	hSpCas9	negative selection	5367376
32543888	32543910	9	+	27760321	HT29	viability after 10 days	ACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.6752761681902641	[595,464]	[1049,1222,907]	8	hSpCas9	negative selection	5367377
32543966	32543988	9	-	27760321	HT29	viability after 10 days	TACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	0.2916856236045344	[134,105]	[197,264,93]	4	hSpCas9	negative selection	5367378
32543985	32544007	9	+	27760321	HT29	viability after 10 days	GTAGCGAAATCGTCGATCAGGG	TOPORS	ENSG00000197579	0.43945721911438934	[348,272]	[198,1036,361]	6	hSpCas9	negative selection	5367379
32543429	32543451	9	-	27760321	MOLM13	viability	GCCCGATCTCCTTTTAACATGG	TOPORS	ENSG00000197579	0.16914866483988658	[397,316]	[138,298]	1	hSpCas9	negative selection	5450838
32543611	32543633	9	+	27760321	MOLM13	viability	GTAAGTTCACGTTTTAACCAGG	TOPORS	ENSG00000197579	-5.297747035503205	[62,74]	[0,0]	-9	hSpCas9	negative selection	5450839
32543888	32543910	9	+	27760321	MOLM13	viability	ACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.0013344050349246572	[867,595]	[321,481]	0	hSpCas9	negative selection	5450840
32543966	32543988	9	-	27760321	MOLM13	viability	TACCGTACAACTCTGACAAGGG	TOPORS	ENSG00000197579	0.24558342723578064	[189,134]	[32,170]	1	hSpCas9	negative selection	5450841
32543985	32544007	9	+	27760321	MOLM13	viability	GTAGCGAAATCGTCGATCAGGG	TOPORS	ENSG00000197579	0.025859938820306322	[403,348]	[98,314]	0	hSpCas9	negative selection	5450842
32550926	32550949	9	-	27260156	BXPC3	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.2830455435589945	[149]	[182,151,223,208]	6	hSpCas9	negative selection	5577093
32550854	32550877	9	+	27260156	BXPC3	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.06819222781635093	[683]	[726,673,848,752]	1	hSpCas9	negative selection	5577094
32543967	32543990	9	-	27260156	BXPC3	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.030398641960550643	[749]	[726,685,708,1129]	0	hSpCas9	negative selection	5577095
32542167	32542190	9	-	27260156	BXPC3	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.15427531228086866	[244]	[234,216,232,234]	-4	hSpCas9	negative selection	5641342
32550830	32550853	9	-	27260156	BXPC3	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.3216203270536909	[673]	[832,720,937,1062]	7	hSpCas9	negative selection	5641343
32543788	32543811	9	+	27260156	BXPC3	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.4454397637767858	[369]	[440,507,524,655]	8	hSpCas9	negative selection	5641344
32550926	32550949	9	-	27260156	A673	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.33574725748809753	[149]	[321,166,211,219]	7	hSpCas9	negative selection	5698344
32550854	32550877	9	+	27260156	A673	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.003265223779251536	[683]	[806,702,870,915]	0	hSpCas9	negative selection	5698345
32543967	32543990	9	-	27260156	A673	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.0751700492574573	[749]	[961,791,1039,1006]	1	hSpCas9	negative selection	5698346
32542167	32542190	9	-	27260156	A673	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.07499738239015963	[244]	[313,363,242,317]	1	hSpCas9	negative selection	5762593
32550830	32550853	9	-	27260156	A673	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.26795010232000616	[673]	[1203,784,955,982]	6	hSpCas9	negative selection	5762594
32543788	32543811	9	+	27260156	A673	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.35329757783516624	[369]	[637,470,549,623]	7	hSpCas9	negative selection	5762595
32550926	32550949	9	-	27260156	A375	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	-0.05733308006633675	[149]	[177,245,204,66]	-1	hSpCas9	negative selection	5819595
32550854	32550877	9	+	27260156	A375	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	-0.0304565033224502	[683]	[1120,1019,465,578]	0	hSpCas9	negative selection	5819596
32543967	32543990	9	-	27260156	A375	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.0895630969578286	[749]	[976,909,684,740]	-1	hSpCas9	negative selection	5819597
32542167	32542190	9	-	27260156	A375	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.200785388205585	[244]	[262,213,428,384]	3	hSpCas9	negative selection	5883844
32550830	32550853	9	-	27260156	A375	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.47769240051868844	[673]	[979,1087,1568,779]	7	hSpCas9	negative selection	5883845
32543788	32543811	9	+	27260156	A375	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.483749049711816	[369]	[680,617,676,458]	7	hSpCas9	negative selection	5883846
32550926	32550949	9	-	27260156	COLO741	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.2950128485814867	[149]	[309,108,287]	6	hSpCas9	negative selection	5940846
32550854	32550877	9	+	27260156	COLO741	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.06408388078004557	[683]	[1092,945,728]	1	hSpCas9	negative selection	5940847
32543967	32543990	9	-	27260156	COLO741	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.1238426165718548	[749]	[1267,1021,871]	2	hSpCas9	negative selection	5940848
32542167	32542190	9	-	27260156	COLO741	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.21995763918070588	[244]	[266,247,288]	-5	hSpCas9	negative selection	6005095
32550830	32550853	9	-	27260156	COLO741	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.24475150637336307	[673]	[1206,1120,765]	5	hSpCas9	negative selection	6005096
32543788	32543811	9	+	27260156	COLO741	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.6522196560340127	[369]	[641,932,650]	9	hSpCas9	negative selection	6005097
32550926	32550949	9	-	27260156	CAL120	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.25350793188945864	[149]	[173,254,230]	4	hSpCas9	negative selection	6062097
32550854	32550877	9	+	27260156	CAL120	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.07732325025874753	[683]	[994,798,913]	1	hSpCas9	negative selection	6062098
32543967	32543990	9	-	27260156	CAL120	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.12229163699126178	[749]	[1003,675,912]	-2	hSpCas9	negative selection	6062099
32542167	32542190	9	-	27260156	CAL120	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.5966191025276222	[244]	[657,208,543]	8	hSpCas9	negative selection	6126346
32550830	32550853	9	-	27260156	CAL120	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.49494124150356433	[673]	[1223,991,1332]	7	hSpCas9	negative selection	6126347
32543788	32543811	9	+	27260156	CAL120	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.5919682069562128	[369]	[494,931,625]	8	hSpCas9	negative selection	6126348
32550926	32550949	9	-	27260156	CADOES1	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	-0.25912882763766043	[149]	[60,91,205,106]	-4	hSpCas9	negative selection	6183348
32550854	32550877	9	+	27260156	CADOES1	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.09765527430917587	[683]	[738,686,659,634]	1	hSpCas9	negative selection	6183349
32543967	32543990	9	-	27260156	CADOES1	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.2822994235877851	[749]	[572,589,540,590]	-5	hSpCas9	negative selection	6183350
32542167	32542190	9	-	27260156	CADOES1	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.04659644924005646	[244]	[240,260,198,179]	-1	hSpCas9	negative selection	6247597
32550830	32550853	9	-	27260156	CADOES1	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.2225303873203679	[673]	[794,610,639,884]	4	hSpCas9	negative selection	6247598
32543788	32543811	9	+	27260156	CADOES1	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.8080259313878168	[369]	[557,429,759,663]	9	hSpCas9	negative selection	6247599
32550926	32550949	9	-	27260156	EWS502	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.0779813186899867	[149]	[114,126,279,156]	1	hSpCas9	negative selection	6304599
32550854	32550877	9	+	27260156	EWS502	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.022046921163591415	[683]	[713,810,780,625]	0	hSpCas9	negative selection	6304600
32543967	32543990	9	-	27260156	EWS502	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.049161352268208613	[749]	[784,733,830,951]	0	hSpCas9	negative selection	6304601
32542167	32542190	9	-	27260156	EWS502	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.20555531486636835	[244]	[283,251,420,239]	3	hSpCas9	negative selection	6368848
32550830	32550853	9	-	27260156	EWS502	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.1518839661247644	[673]	[783,1004,591,776]	2	hSpCas9	negative selection	6368849
32543788	32543811	9	+	27260156	EWS502	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.5684630852220447	[369]	[542,552,589,646]	8	hSpCas9	negative selection	6368850
32550926	32550949	9	-	27260156	EW8	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.2285406890243311	[149]	[142,107,70,258]	4	hSpCas9	negative selection	6425850
32550854	32550877	9	+	27260156	EW8	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	-0.012219478426973795	[683]	[816,383,512,517]	0	hSpCas9	negative selection	6425851
32543967	32543990	9	-	27260156	EW8	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.09993549979125504	[749]	[742,598,440,524]	-2	hSpCas9	negative selection	6425852
32542167	32542190	9	-	27260156	EW8	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.011188323985617532	[244]	[235,209,136,218]	0	hSpCas9	negative selection	6490099
32550830	32550853	9	-	27260156	EW8	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.3627124007326564	[673]	[794,610,726,679]	6	hSpCas9	negative selection	6490100
32543788	32543811	9	+	27260156	EW8	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.7570077066384251	[369]	[500,508,631,361]	9	hSpCas9	negative selection	6490101
32550926	32550949	9	-	27260156	CORL105	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.274639866190761	[149]	[262,192,206,187]	5	hSpCas9	negative selection	6547101
32550854	32550877	9	+	27260156	CORL105	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.24281967239073987	[683]	[1108,916,1000,777]	4	hSpCas9	negative selection	6547102
32543967	32543990	9	-	27260156	CORL105	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.27023856801327395	[749]	[1086,959,1178,1030]	5	hSpCas9	negative selection	6547103
32542167	32542190	9	-	27260156	CORL105	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.4637215345373916	[244]	[309,319,695,301]	8	hSpCas9	negative selection	6611350
32550830	32550853	9	-	27260156	CORL105	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.18296878309950548	[673]	[789,759,1172,901]	3	hSpCas9	negative selection	6611351
32543788	32543811	9	+	27260156	CORL105	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.418300406438764	[369]	[692,569,636,428]	7	hSpCas9	negative selection	6611352
32550926	32550949	9	-	27260156	HS294T	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.4002726794577698	[149]	[47,40,123,100]	5	hSpCas9	negative selection	6668352
32550854	32550877	9	+	27260156	HS294T	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	-0.010890855344203976	[683]	[195,342,279,227]	0	hSpCas9	negative selection	6668353
32543967	32543990	9	-	27260156	HS294T	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.1787789447692648	[749]	[255,290,305,494]	2	hSpCas9	negative selection	6668354
32542167	32542190	9	-	27260156	HS294T	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.5392696222916069	[244]	[106,134,84,243]	7	hSpCas9	negative selection	6732601
32550830	32550853	9	-	27260156	HS294T	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	-0.01559474361819968	[673]	[314,299,181,219]	0	hSpCas9	negative selection	6732602
32543788	32543811	9	+	27260156	HS294T	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.6794691374079171	[369]	[147,260,261,255]	8	hSpCas9	negative selection	6732603
32550926	32550949	9	-	27260156	HCC44	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.6019802219694428	[149]	[222,254,422,155]	8	hSpCas9	negative selection	6789603
32550854	32550877	9	+	27260156	HCC44	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.17879609177481692	[683]	[696,685,1160,1006]	3	hSpCas9	negative selection	6789604
32543967	32543990	9	-	27260156	HCC44	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.0625513432121807	[749]	[987,727,1034,843]	1	hSpCas9	negative selection	6789605
32542167	32542190	9	-	27260156	HCC44	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.18569566262795167	[244]	[326,266,301,365]	3	hSpCas9	negative selection	6853852
32550830	32550853	9	-	27260156	HCC44	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.415791056774064	[673]	[1090,806,1459,820]	6	hSpCas9	negative selection	6853853
32543788	32543811	9	+	27260156	HCC44	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.42553559531715285	[369]	[505,432,699,638]	7	hSpCas9	negative selection	6853854
32550926	32550949	9	-	27260156	G402	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	-0.5813501868676203	[149]	[120,246,113,18]	-6	hSpCas9	negative selection	6910854
32550854	32550877	9	+	27260156	G402	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.03494324458802711	[683]	[999,967,483,985]	0	hSpCas9	negative selection	6910855
32543967	32543990	9	-	27260156	G402	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.018327922127002738	[749]	[1156,1035,554,906]	0	hSpCas9	negative selection	6910856
32542167	32542190	9	-	27260156	G402	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.41473257873467584	[244]	[347,141,231,188]	-5	hSpCas9	negative selection	6975103
32550830	32550853	9	-	27260156	G402	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.6329978886580498	[673]	[987,1748,1268,1085]	7	hSpCas9	negative selection	6975104
32543788	32543811	9	+	27260156	G402	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	1.226648205202188	[369]	[659,714,1077,1661]	9	hSpCas9	negative selection	6975105
32550926	32550949	9	-	27260156	L33	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.6920920817855172	[149]	[251,107,158,200]	9	hSpCas9	negative selection	7032105
32550854	32550877	9	+	27260156	L33	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	-0.10431020245352296	[683]	[825,271,315,547]	-2	hSpCas9	negative selection	7032106
32543967	32543990	9	-	27260156	L33	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.07836990572352742	[749]	[810,278,452,626]	-2	hSpCas9	negative selection	7032107
32542167	32542190	9	-	27260156	L33	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.25678076362475055	[244]	[154,86,120,260]	-5	hSpCas9	negative selection	7096354
32550830	32550853	9	-	27260156	L33	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	-0.22245121107936078	[673]	[570,235,417,499]	-5	hSpCas9	negative selection	7096355
32543788	32543811	9	+	27260156	L33	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.3512891678397509	[369]	[496,186,304,448]	7	hSpCas9	negative selection	7096356
32550926	32550949	9	-	27260156	K562	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.7835410530361656	[149]	[556,169,168,62]	8	hSpCas9	negative selection	7153356
32550854	32550877	9	+	27260156	K562	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	-0.05620420344089566	[683]	[663,917,399,396]	0	hSpCas9	negative selection	7153357
32543967	32543990	9	-	27260156	K562	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.28322294377143065	[749]	[650,620,408,519]	-4	hSpCas9	negative selection	7153358
32542167	32542190	9	-	27260156	K562	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.29540941983089164	[244]	[222,204,285,336]	3	hSpCas9	negative selection	7217605
32550830	32550853	9	-	27260156	K562	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.23570180497050075	[673]	[943,415,776,683]	3	hSpCas9	negative selection	7217606
32543788	32543811	9	+	27260156	K562	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.967663318845654	[369]	[771,522,668,609]	9	hSpCas9	negative selection	7217607
32550926	32550949	9	-	27260156	HT29	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.2323526541660188	[149]	[217,336,140,174]	4	hSpCas9	negative selection	7274607
32550854	32550877	9	+	27260156	HT29	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.12054167097016877	[683]	[922,1038,924,753]	2	hSpCas9	negative selection	7274608
32543967	32543990	9	-	27260156	HT29	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.35499947861942016	[749]	[1175,1127,1225,1127]	7	hSpCas9	negative selection	7274609
32542167	32542190	9	-	27260156	HT29	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.11975611984992152	[244]	[265,217,375,233]	-2	hSpCas9	negative selection	7338856
32550830	32550853	9	-	27260156	HT29	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.31554467090622207	[673]	[1034,992,914,1114]	6	hSpCas9	negative selection	7338857
32543788	32543811	9	+	27260156	HT29	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.4842878766131262	[369]	[753,529,570,654]	8	hSpCas9	negative selection	7338858
32550926	32550949	9	-	27260156	MHHES1	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.42096577216012365	[149]	[177,361,176,196]	7	hSpCas9	negative selection	7395858
32550854	32550877	9	+	27260156	MHHES1	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	-0.08881396288347676	[683]	[710,937,736,554]	-2	hSpCas9	negative selection	7395859
32543967	32543990	9	-	27260156	MHHES1	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.00031738961736216265	[749]	[1017,902,901,617]	0	hSpCas9	negative selection	7395860
32542167	32542190	9	-	27260156	MHHES1	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.2559467038318819	[244]	[309,240,202,185]	-5	hSpCas9	negative selection	7460107
32550830	32550853	9	-	27260156	MHHES1	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.2824599659541033	[673]	[1126,1074,865,696]	5	hSpCas9	negative selection	7460108
32543788	32543811	9	+	27260156	MHHES1	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.543177433784847	[369]	[612,778,600,471]	8	hSpCas9	negative selection	7460109
32550926	32550949	9	-	27260156	MEWO	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.4650761387805773	[149]	[216,114,253]	8	hSpCas9	negative selection	7517109
32550854	32550877	9	+	27260156	MEWO	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.11190288336304466	[683]	[705,743,626]	2	hSpCas9	negative selection	7517110
32543967	32543990	9	-	27260156	MEWO	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.008759244599879423	[749]	[765,574,764]	0	hSpCas9	negative selection	7517111
32542167	32542190	9	-	27260156	MEWO	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.26561983755059493	[244]	[265,99,220]	-5	hSpCas9	negative selection	7581358
32550830	32550853	9	-	27260156	MEWO	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.21116975884743794	[673]	[850,765,595]	4	hSpCas9	negative selection	7581359
32543788	32543811	9	+	27260156	MEWO	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.08068706376318086	[369]	[507,288,328]	1	hSpCas9	negative selection	7581360
32550926	32550949	9	-	27260156	LNCAPCLONEFGC	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.2507958497658376	[149]	[114,185,249,107]	4	hSpCas9	negative selection	7638360
32550854	32550877	9	+	27260156	LNCAPCLONEFGC	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.32956891875833105	[683]	[740,625,1042,753]	5	hSpCas9	negative selection	7638361
32543967	32543990	9	-	27260156	LNCAPCLONEFGC	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.07906674799669566	[749]	[484,790,686,608]	-1	hSpCas9	negative selection	7638362
32542167	32542190	9	-	27260156	LNCAPCLONEFGC	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.10570683606124398	[244]	[143,202,364,265]	1	hSpCas9	negative selection	7702609
32550830	32550853	9	-	27260156	LNCAPCLONEFGC	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.6593442520336812	[673]	[1010,1121,875,822]	9	hSpCas9	negative selection	7702610
32543788	32543811	9	+	27260156	LNCAPCLONEFGC	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.45564006500400756	[369]	[478,494,428,427]	7	hSpCas9	negative selection	7702611
32550926	32550949	9	-	27260156	PANC0327	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.753828568762284	[149]	[292,116,161,345]	9	hSpCas9	negative selection	7759611
32550854	32550877	9	+	27260156	PANC0327	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.10641448534396947	[683]	[880,643,526,583]	1	hSpCas9	negative selection	7759612
32543967	32543990	9	-	27260156	PANC0327	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.20456671279073801	[749]	[890,678,666,854]	3	hSpCas9	negative selection	7759613
32542167	32542190	9	-	27260156	PANC0327	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.3504563683521482	[244]	[399,73,128,110]	-5	hSpCas9	negative selection	7823860
32550830	32550853	9	-	27260156	PANC0327	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.21061768971196249	[673]	[797,665,592,725]	3	hSpCas9	negative selection	7823861
32543788	32543811	9	+	27260156	PANC0327	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	1.0035415039498268	[369]	[530,581,674,846]	9	hSpCas9	negative selection	7823862
32550926	32550949	9	-	27260156	NCIH2009	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.39516862821878673	[149]	[219,350,242]	5	hSpCas9	negative selection	7880862
32550854	32550877	9	+	27260156	NCIH2009	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.09557113532246586	[683]	[1337,812,976]	1	hSpCas9	negative selection	7880863
32543967	32543990	9	-	27260156	NCIH2009	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.22508063409335988	[749]	[1506,1173,1047]	3	hSpCas9	negative selection	7880864
32542167	32542190	9	-	27260156	NCIH2009	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.2698652807366675	[244]	[498,439,314]	3	hSpCas9	negative selection	7945111
32550830	32550853	9	-	27260156	NCIH2009	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.2948137657074149	[673]	[1055,1099,1288]	4	hSpCas9	negative selection	7945112
32543788	32543811	9	+	27260156	NCIH2009	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.8888366410123321	[369]	[1414,765,782]	9	hSpCas9	negative selection	7945113
32550926	32550949	9	-	27260156	NCIH1373	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.13713123235348434	[149]	[182,125,233,52]	1	hSpCas9	negative selection	8002113
32550854	32550877	9	+	27260156	NCIH1373	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.051699564098448225	[683]	[823,923,750,172]	0	hSpCas9	negative selection	8002114
32543967	32543990	9	-	27260156	NCIH1373	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.2799452977857676	[749]	[820,414,816,200]	-3	hSpCas9	negative selection	8002115
32542167	32542190	9	-	27260156	NCIH1373	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.17573229743333563	[244]	[566,278,145,76]	1	hSpCas9	negative selection	8066362
32550830	32550853	9	-	27260156	NCIH1373	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.8571249889058146	[673]	[1915,780,1555,356]	8	hSpCas9	negative selection	8066363
32543788	32543811	9	+	27260156	NCIH1373	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.973657754456402	[369]	[934,726,927,178]	8	hSpCas9	negative selection	8066364
32550926	32550949	9	-	27260156	PATU8902	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.5775452823500729	[149]	[237,363,300,349]	6	hSpCas9	negative selection	8123364
32550854	32550877	9	+	27260156	PATU8902	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.33117951786998734	[683]	[1071,1097,1237,1389]	3	hSpCas9	negative selection	8123365
32543967	32543990	9	-	27260156	PATU8902	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.4266018074771265	[749]	[1826,1428,1119,1281]	4	hSpCas9	negative selection	8123366
32542167	32542190	9	-	27260156	PATU8902	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	1.0430738009878506	[244]	[972,300,673,882]	9	hSpCas9	negative selection	8187613
32550830	32550853	9	-	27260156	PATU8902	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.46654163602631094	[673]	[889,1022,1607,1618]	5	hSpCas9	negative selection	8187614
32543788	32543811	9	+	27260156	PATU8902	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.7432444793395641	[369]	[825,506,843,1325]	7	hSpCas9	negative selection	8187615
32550926	32550949	9	-	27260156	PANC1	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	-0.21379337331667725	[149]	[117,211,104,39]	-3	hSpCas9	negative selection	8244615
32550854	32550877	9	+	27260156	PANC1	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	-0.18917494051720452	[683]	[439,526,633,464]	-3	hSpCas9	negative selection	8244616
32543967	32543990	9	-	27260156	PANC1	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.7488361942953249	[749]	[424,510,383,253]	-8	hSpCas9	negative selection	8244617
32542167	32542190	9	-	27260156	PANC1	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.07023958677053099	[244]	[163,258,239,155]	-1	hSpCas9	negative selection	8308864
32550830	32550853	9	-	27260156	PANC1	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	-0.07576800363005076	[673]	[578,866,498,341]	-1	hSpCas9	negative selection	8308865
32543788	32543811	9	+	27260156	PANC1	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.44326850989150224	[369]	[285,621,460,399]	7	hSpCas9	negative selection	8308866
32550926	32550949	9	-	27260156	PANC0813	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.2570543528051965	[149]	[232,176,153,275]	4	hSpCas9	negative selection	8365866
32550854	32550877	9	+	27260156	PANC0813	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.019760259725778773	[683]	[1059,950,749,533]	0	hSpCas9	negative selection	8365867
32543967	32543990	9	-	27260156	PANC0813	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.07752069764989189	[749]	[778,833,880,838]	-1	hSpCas9	negative selection	8365868
32542167	32542190	9	-	27260156	PANC0813	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.2985148941641428	[244]	[346,426,351,291]	5	hSpCas9	negative selection	8430115
32550830	32550853	9	-	27260156	PANC0813	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.17475776818465694	[673]	[1100,850,940,709]	3	hSpCas9	negative selection	8430116
32543788	32543811	9	+	27260156	PANC0813	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.5083898066805749	[369]	[706,729,353,683]	7	hSpCas9	negative selection	8430117
32550926	32550949	9	-	27260156	RDES	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.03483299045719823	[149]	[171,119,212,208]	0	hSpCas9	negative selection	8487117
32550854	32550877	9	+	27260156	RDES	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	-0.03923250766793296	[683]	[611,651,837,1023]	0	hSpCas9	negative selection	8487118
32543967	32543990	9	-	27260156	RDES	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.05925907938507635	[749]	[555,834,817,1192]	-1	hSpCas9	negative selection	8487119
32542167	32542190	9	-	27260156	RDES	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.07344524154186127	[244]	[286,284,255,358]	1	hSpCas9	negative selection	8551366
32550830	32550853	9	-	27260156	RDES	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.23021365926304072	[673]	[727,967,947,1015]	4	hSpCas9	negative selection	8551367
32543788	32543811	9	+	27260156	RDES	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.533581802864953	[369]	[491,613,653,730]	8	hSpCas9	negative selection	8551368
32550926	32550949	9	-	27260156	PC3	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.3137278096482894	[149]	[152,137,356,154]	6	hSpCas9	negative selection	8608368
32550854	32550877	9	+	27260156	PC3	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.07003189749946859	[683]	[450,664,1274,739]	1	hSpCas9	negative selection	8608369
32543967	32543990	9	-	27260156	PC3	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.12624882388017533	[749]	[421,1125,1201,745]	3	hSpCas9	negative selection	8608370
32542167	32542190	9	-	27260156	PC3	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.3387509138353675	[244]	[140,126,293,257]	-6	hSpCas9	negative selection	8672617
32550830	32550853	9	-	27260156	PC3	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.08294297330703537	[673]	[418,628,1369,754]	2	hSpCas9	negative selection	8672618
32543788	32543811	9	+	27260156	PC3	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.3697189052473376	[369]	[435,266,888,438]	7	hSpCas9	negative selection	8672619
32550926	32550949	9	-	27260156	PATU8988T	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.4402301581180652	[149]	[145,180,184,279]	7	hSpCas9	negative selection	8729619
32550854	32550877	9	+	27260156	PATU8988T	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.1318716616345288	[683]	[754,838,642,666]	2	hSpCas9	negative selection	8729620
32543967	32543990	9	-	27260156	PATU8988T	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.2604559338527879	[749]	[372,816,587,666]	-4	hSpCas9	negative selection	8729621
32542167	32542190	9	-	27260156	PATU8988T	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.1792085632013175	[244]	[202,277,306,285]	3	hSpCas9	negative selection	8793868
32550830	32550853	9	-	27260156	PATU8988T	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.5169498971123132	[673]	[538,1052,1142,1006]	8	hSpCas9	negative selection	8793869
32543788	32543811	9	+	27260156	PATU8988T	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.48591219507262506	[369]	[488,454,618,427]	7	hSpCas9	negative selection	8793870
32550926	32550949	9	-	27260156	T47D	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.387194630068314	[149]	[223,223,284,178]	7	hSpCas9	negative selection	8850870
32550854	32550877	9	+	27260156	T47D	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	-0.0694477536845235	[683]	[772,756,682,827]	-1	hSpCas9	negative selection	8850871
32543967	32543990	9	-	27260156	T47D	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.08656343026426316	[749]	[945,868,936,964]	1	hSpCas9	negative selection	8850872
32542167	32542190	9	-	27260156	T47D	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.12179763248940134	[244]	[349,259,355,278]	2	hSpCas9	negative selection	8915119
32550830	32550853	9	-	27260156	T47D	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.26551140999321365	[673]	[890,961,910,1011]	5	hSpCas9	negative selection	8915120
32543788	32543811	9	+	27260156	T47D	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.5223810549283205	[369]	[687,555,538,702]	9	hSpCas9	negative selection	8915121
32550926	32550949	9	-	27260156	SU8686	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.8137199971148066	[149]	[145,349,319,224]	9	hSpCas9	negative selection	8972121
32550854	32550877	9	+	27260156	SU8686	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.006431117463148173	[683]	[635,732,589,770]	0	hSpCas9	negative selection	8972122
32543967	32543990	9	-	27260156	SU8686	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.11719030188264812	[749]	[888,743,714,879]	2	hSpCas9	negative selection	8972123
32542167	32542190	9	-	27260156	SU8686	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.3020947893900431	[244]	[386,188,267,365]	5	hSpCas9	negative selection	9036370
32550830	32550853	9	-	27260156	SU8686	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.10093421987021789	[673]	[667,562,691,1010]	1	hSpCas9	negative selection	9036371
32543788	32543811	9	+	27260156	SU8686	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.5200653047163692	[369]	[442,504,477,715]	8	hSpCas9	negative selection	9036372
32550926	32550949	9	-	27260156	SKES1	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.3554348096070197	[149]	[260,243,145,135]	7	hSpCas9	negative selection	9093372
32550854	32550877	9	+	27260156	SKES1	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.10994361370903405	[683]	[1012,753,628,599]	2	hSpCas9	negative selection	9093373
32543967	32543990	9	-	27260156	SKES1	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.0464264091737312	[749]	[829,996,618,683]	1	hSpCas9	negative selection	9093374
32542167	32542190	9	-	27260156	SKES1	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	0.11704580028702372	[244]	[225,320,309,207]	2	hSpCas9	negative selection	9157621
32550830	32550853	9	-	27260156	SKES1	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.12692139336435304	[673]	[997,782,594,611]	2	hSpCas9	negative selection	9157622
32543788	32543811	9	+	27260156	SKES1	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.42775151234920716	[369]	[638,609,374,402]	8	hSpCas9	negative selection	9157623
32550926	32550949	9	-	27260156	TOV112D	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.04547922204311994	[149]	[165,218,147,104]	0	hSpCas9	negative selection	9214623
32550854	32550877	9	+	27260156	TOV112D	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.17888972287388116	[683]	[636,1214,779,570]	3	hSpCas9	negative selection	9214624
32543967	32543990	9	-	27260156	TOV112D	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.05516324712760878	[749]	[677,911,639,703]	-1	hSpCas9	negative selection	9214625
32542167	32542190	9	-	27260156	TOV112D	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.4969250324553205	[244]	[146,170,190,182]	-7	hSpCas9	negative selection	9278872
32550830	32550853	9	-	27260156	TOV112D	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.08208768928768662	[673]	[601,913,749,632]	1	hSpCas9	negative selection	9278873
32543788	32543811	9	+	27260156	TOV112D	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.34215891074440424	[369]	[367,859,277,459]	6	hSpCas9	negative selection	9278874
32550926	32550949	9	-	27260156	TC71	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	0.40573418725288724	[149]	[185,220,231,212]	8	hSpCas9	negative selection	9335874
32550854	32550877	9	+	27260156	TC71	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	0.02295523238632169	[683]	[740,741,648,857]	0	hSpCas9	negative selection	9335875
32543967	32543990	9	-	27260156	TC71	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	0.045479164183030885	[749]	[715,760,952,890]	1	hSpCas9	negative selection	9335876
32542167	32542190	9	-	27260156	TC71	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.35937609722289365	[244]	[240,170,182,224]	-7	hSpCas9	negative selection	9400123
32550830	32550853	9	-	27260156	TC71	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.18816617301824923	[673]	[756,732,865,943]	5	hSpCas9	negative selection	9400124
32543788	32543811	9	+	27260156	TC71	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.3678821322975579	[369]	[498,419,634,487]	8	hSpCas9	negative selection	9400125
32550926	32550949	9	-	27260156	TC32	viability	GTCTCCGCTGTCTCGCGAGGAGG	TOPORS	ENSG00000197579	-0.18545886400036604	[149]	[111,135,78,150]	-3	hSpCas9	negative selection	9457125
32550854	32550877	9	+	27260156	TC32	viability	AGGATCCGCGAAGGCGTACCCGG	TOPORS	ENSG00000197579	-0.32460852002359464	[683]	[354,378,751,658]	-5	hSpCas9	negative selection	9457126
32543967	32543990	9	-	27260156	TC32	viability	GCTACCGTACAACTCTGACAAGG	TOPORS	ENSG00000197579	-0.0265702427996809	[749]	[640,473,775,954]	0	hSpCas9	negative selection	9457127
32542167	32542190	9	-	27260156	TC32	viability	CTGCATCTACCGGGACTGACCGG	TOPORS	ENSG00000197579	-0.79574165077099	[244]	[105,49,252,172]	-9	hSpCas9	negative selection	9521374
32550830	32550853	9	-	27260156	TC32	viability	CCGACACCGACCTAGCTTTCTGG	TOPORS	ENSG00000197579	0.42206986886163966	[673]	[711,781,1062,864]	7	hSpCas9	negative selection	9521375
32543788	32543811	9	+	27260156	TC32	viability	GATCTTTCATCTGCCGTAGTTGG	TOPORS	ENSG00000197579	0.7625230726268775	[369]	[486,472,765,691]	9	hSpCas9	negative selection	9521376
32542097	32542120	9	-	27869803	HPAFII	viability after 27 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.44763083591368424	[238]	[190,154,NaN]	3	hSpCas9	negative selection	9605730
32543374	32543397	9	+	27869803	HPAFII	viability after 27 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	0.33022092750507914	[84]	[59,52,NaN]	2	hSpCas9	negative selection	9605731
32543811	32543834	9	-	27869803	HPAFII	viability after 27 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.6628193038224415	[455]	[204,524,NaN]	5	hSpCas9	negative selection	9605732
32550872	32550895	9	-	27869803	HPAFII	viability after 27 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-1.747579855317031	[53]	[2,12,NaN]	-8	hSpCas9	negative selection	9605733
32550882	32550905	9	+	27869803	HPAFII	viability after 27 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.20158376846150194	[413]	[71,286,NaN]	-1	hSpCas9	negative selection	9605734
32550925	32550948	9	-	27869803	HPAFII	viability after 27 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	-0.8602087104279366	[252]	[105,45,NaN]	-6	hSpCas9	negative selection	9605735
32542097	32542120	9	-	27869803	HPAFII	viability after 15 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	-0.10864242598408952	[238]	[355,164,NaN]	-1	hSpCas9	negative selection	9688179
32543374	32543397	9	+	27869803	HPAFII	viability after 15 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	-0.3494711160841577	[84]	[67,73,NaN]	-4	hSpCas9	negative selection	9688180
32543811	32543834	9	-	27869803	HPAFII	viability after 15 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	-0.04391660530872177	[455]	[475,474,NaN]	0	hSpCas9	negative selection	9688181
32550872	32550895	9	-	27869803	HPAFII	viability after 15 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-3.147483628930363	[53]	[0,9,NaN]	-9	hSpCas9	negative selection	9688182
32550882	32550905	9	+	27869803	HPAFII	viability after 15 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.4986497777657811	[413]	[280,335,NaN]	-5	hSpCas9	negative selection	9688183
32550925	32550948	9	-	27869803	HPAFII	viability after 15 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	-0.37636827408716433	[252]	[243,187,NaN]	-4	hSpCas9	negative selection	9688184
32542097	32542120	9	-	27869803	ASPC1	viability after 36 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.9119738253236783	[548]	[278,502,300]	8	hSpCas9	negative selection	9770628
32543374	32543397	9	+	27869803	ASPC1	viability after 36 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	0.10859872417318206	[194]	[167,79,0]	1	hSpCas9	negative selection	9770629
32543811	32543834	9	-	27869803	ASPC1	viability after 36 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	-0.08266813129527706	[1426]	[452,673,315]	-1	hSpCas9	negative selection	9770630
32550872	32550895	9	-	27869803	ASPC1	viability after 36 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-2.2107903446284736	[86]	[4,0,11]	-9	hSpCas9	negative selection	9770631
32550882	32550905	9	+	27869803	ASPC1	viability after 36 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	0.13487383532992392	[1028]	[662,242,321]	1	hSpCas9	negative selection	9770632
32550925	32550948	9	-	27869803	ASPC1	viability after 36 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.3654892409667953	[478]	[370,193,120]	3	hSpCas9	negative selection	9770633
32542097	32542120	9	-	27869803	PATU8988S	viability after 35 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.07436068064232716	[507]	[179,250,NaN]	0	hSpCas9	negative selection	9853077
32543374	32543397	9	+	27869803	PATU8988S	viability after 35 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	0.04211517871734882	[133]	[84,25,NaN]	0	hSpCas9	negative selection	9853078
32543811	32543834	9	-	27869803	PATU8988S	viability after 35 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	-0.30860684975161434	[1222]	[487,306,NaN]	-3	hSpCas9	negative selection	9853079
32550872	32550895	9	-	27869803	PATU8988S	viability after 35 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-0.08727503597750585	[69]	[42,9,NaN]	-1	hSpCas9	negative selection	9853080
32550882	32550905	9	+	27869803	PATU8988S	viability after 35 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.4947963813374133	[996]	[266,302,NaN]	-5	hSpCas9	negative selection	9853081
32550925	32550948	9	-	27869803	PATU8988S	viability after 35 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.08204407287891576	[481]	[198,211,NaN]	1	hSpCas9	negative selection	9853082
32542097	32542120	9	-	27869803	PATU8988S	viability after 31 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	-0.04344080789864661	[507]	[163,237,NaN]	0	hSpCas9	negative selection	9935526
32543374	32543397	9	+	27869803	PATU8988S	viability after 31 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	-0.32934612728992363	[133]	[71,4,NaN]	-4	hSpCas9	negative selection	9935527
32543811	32543834	9	-	27869803	PATU8988S	viability after 31 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	-0.24812459092656403	[1222]	[447,362,NaN]	-3	hSpCas9	negative selection	9935528
32550872	32550895	9	-	27869803	PATU8988S	viability after 31 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	0.19370409964337965	[69]	[45,13,NaN]	2	hSpCas9	negative selection	9935529
32550882	32550905	9	+	27869803	PATU8988S	viability after 31 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.15237345113257184	[996]	[263,476,NaN]	-2	hSpCas9	negative selection	9935530
32550925	32550948	9	-	27869803	PATU8988S	viability after 31 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	0.05069556997892566	[481]	[140,272,NaN]	0	hSpCas9	negative selection	9935531
32542097	32542120	9	-	27869803	HPAFII	viability after 35 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.49108221019448955	[238]	[162,177,NaN]	3	hSpCas9	negative selection	10017975
32543374	32543397	9	+	27869803	HPAFII	viability after 35 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	-0.4764209211279937	[84]	[5,58,NaN]	-3	hSpCas9	negative selection	10017976
32543811	32543834	9	-	27869803	HPAFII	viability after 35 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	1.3397845122487047	[455]	[255,953,NaN]	8	hSpCas9	negative selection	10017977
32550872	32550895	9	-	27869803	HPAFII	viability after 35 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-0.43048706877142084	[53]	[0,41,NaN]	-3	hSpCas9	negative selection	10017978
32550882	32550905	9	+	27869803	HPAFII	viability after 35 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.20413649992108773	[413]	[45,334,NaN]	-1	hSpCas9	negative selection	10017979
32550925	32550948	9	-	27869803	HPAFII	viability after 35 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	-0.5499220219759702	[252]	[118,51,NaN]	-3	hSpCas9	negative selection	10017980
32542097	32542120	9	-	27869803	HPAFII	viability after 31 days	TTTGGAGGGTACTAACGAAGTGG	TOPORS	ENSG00000197579	0.22008486166711916	[238]	[127,186,NaN]	1	hSpCas9	negative selection	10100424
32543374	32543397	9	+	27869803	HPAFII	viability after 31 days	CCTTCTTCGTATGAAGGAGCAGG	TOPORS	ENSG00000197579	-0.16420613805788653	[84]	[32,52,NaN]	-1	hSpCas9	negative selection	10100425
32543811	32543834	9	-	27869803	HPAFII	viability after 31 days	TGAGACAGATTGCAGTAAGGAGG	TOPORS	ENSG00000197579	0.9642442819532462	[455]	[237,783,NaN]	7	hSpCas9	negative selection	10100426
32550872	32550895	9	-	27869803	HPAFII	viability after 31 days	GGGTAGGCGGAGAAGTCGCCGGG	TOPORS	ENSG00000197579	-1.8076253359602266	[53]	[0,16,NaN]	-7	hSpCas9	negative selection	10100427
32550882	32550905	9	+	27869803	HPAFII	viability after 31 days	TCTCCGCCTACCCTCCGAAGCGG	TOPORS	ENSG00000197579	-0.43745024417603734	[413]	[94,254,NaN]	-3	hSpCas9	negative selection	10100428
32550925	32550948	9	-	27869803	HPAFII	viability after 31 days	TCTCCGCTGTCTCGCGAGGAGGG	TOPORS	ENSG00000197579	-0.7743346526396091	[252]	[127,33,NaN]	-5	hSpCas9	negative selection	10100429
32543887	32543910	9	+	28162770	P31FUJ	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.15526824726419597	[566]	[741]	1	hSpCas9	negative selection	10255326
32543029	32543052	9	+	28162770	P31FUJ	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	0.46993175493252815	[434]	[707]	5	hSpCas9	negative selection	10255327
32543821	32543844	9	+	28162770	P31FUJ	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.710335458629945	[206]	[397]	7	hSpCas9	negative selection	10255328
32542359	32542382	9	-	28162770	P31FUJ	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	0.895521892561161	[85]	[187]	8	hSpCas9	negative selection	10255329
32543985	32544008	9	+	28162770	P31FUJ	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.4940480456597692	[228]	[378]	5	hSpCas9	negative selection	10255330
32542381	32542404	9	-	28162770	P31FUJ	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	0.5296053115892508	[325]	[552]	6	hSpCas9	negative selection	10255331
32542144	32542167	9	-	28162770	P31FUJ	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	0.7596641229002138	[95]	[190]	8	hSpCas9	negative selection	10255332
32543903	32543926	9	-	28162770	P31FUJ	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	0.5441553652087165	[184]	[316]	6	hSpCas9	negative selection	10255333
32543277	32543300	9	+	28162770	P31FUJ	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	0.5907629448244847	[707]	[1252]	6	hSpCas9	negative selection	10255334
32543167	32543190	9	-	28162770	P31FUJ	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	0.09369862026280784	[440]	[552]	0	hSpCas9	negative selection	10255335
32543887	32543910	9	+	28162770	TF1	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	NaN	[NaN]	[617]	1	hSpCas9	negative selection	10424692
32543029	32543052	9	+	28162770	TF1	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	NaN	[NaN]	[528]	1	hSpCas9	negative selection	10424693
32543821	32543844	9	+	28162770	TF1	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10424694
32542359	32542382	9	-	28162770	TF1	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10424695
32543985	32544008	9	+	28162770	TF1	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	NaN	[NaN]	[216]	1	hSpCas9	negative selection	10424696
32542381	32542404	9	-	28162770	TF1	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	NaN	[NaN]	[360]	1	hSpCas9	negative selection	10424697
32542144	32542167	9	-	28162770	TF1	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	NaN	[NaN]	[105]	1	hSpCas9	negative selection	10424698
32543903	32543926	9	-	28162770	TF1	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	NaN	[NaN]	[150]	1	hSpCas9	negative selection	10424699
32543277	32543300	9	+	28162770	TF1	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	NaN	[NaN]	[612]	1	hSpCas9	negative selection	10424700
32543167	32543190	9	-	28162770	TF1	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	NaN	[NaN]	[355]	1	hSpCas9	negative selection	10424701
32543887	32543910	9	+	28162770	SKM1	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.07311172981015956	[163]	[304]	0	hSpCas9	negative selection	10594058
32543029	32543052	9	+	28162770	SKM1	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	-0.35557881247625045	[130]	[180]	-3	hSpCas9	negative selection	10594059
32543821	32543844	9	+	28162770	SKM1	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	1.0144995696951151	[48]	[174]	8	hSpCas9	negative selection	10594060
32542359	32542382	9	-	28162770	SKM1	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	1.2269079024589409	[28]	[119]	9	hSpCas9	negative selection	10594061
32543985	32544008	9	+	28162770	SKM1	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	-0.4918530963296748	[69]	[87]	-4	hSpCas9	negative selection	10594062
32542381	32542404	9	-	28162770	SKM1	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	-0.0850361038557994	[131]	[219]	0	hSpCas9	negative selection	10594063
32542144	32542167	9	-	28162770	SKM1	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	0.11910461292442598	[24]	[47]	1	hSpCas9	negative selection	10594064
32543903	32543926	9	-	28162770	SKM1	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	0.39159377507728343	[46]	[108]	4	hSpCas9	negative selection	10594065
32543277	32543300	9	+	28162770	SKM1	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	0.723966671083287	[149]	[437]	7	hSpCas9	negative selection	10594066
32543167	32543190	9	-	28162770	SKM1	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	-0.4032885405997633	[97]	[130]	-3	hSpCas9	negative selection	10594067
32543887	32543910	9	+	28162770	SKM1	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.07311172981015956	[163]	[304]	0	hSpCas9	negative selection	10763424
32543029	32543052	9	+	28162770	SKM1	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	-0.35557881247625045	[130]	[180]	-3	hSpCas9	negative selection	10763425
32543821	32543844	9	+	28162770	SKM1	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	1.0144995696951151	[48]	[174]	8	hSpCas9	negative selection	10763426
32542359	32542382	9	-	28162770	SKM1	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	1.2269079024589409	[28]	[119]	9	hSpCas9	negative selection	10763427
32543985	32544008	9	+	28162770	SKM1	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	-0.4918530963296748	[69]	[87]	-4	hSpCas9	negative selection	10763428
32542381	32542404	9	-	28162770	SKM1	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	-0.0850361038557994	[131]	[219]	0	hSpCas9	negative selection	10763429
32542144	32542167	9	-	28162770	SKM1	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	0.11910461292442598	[24]	[47]	1	hSpCas9	negative selection	10763430
32543903	32543926	9	-	28162770	SKM1	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	0.39159377507728343	[46]	[108]	4	hSpCas9	negative selection	10763431
32543277	32543300	9	+	28162770	SKM1	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	0.723966671083287	[149]	[437]	7	hSpCas9	negative selection	10763432
32543167	32543190	9	-	28162770	SKM1	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	-0.4032885405997633	[97]	[130]	-3	hSpCas9	negative selection	10763433
32543887	32543910	9	+	28162770	PL21	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	-0.4971852516877939	[693]	[213]	-4	hSpCas9	negative selection	10932790
32543029	32543052	9	+	28162770	PL21	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	0.4041535065109133	[315]	[181]	3	hSpCas9	negative selection	10932791
32543821	32543844	9	+	28162770	PL21	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.7676990689490312	[138]	[102]	6	hSpCas9	negative selection	10932792
32542359	32542382	9	-	28162770	PL21	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	0.2423678498786177	[100]	[51]	2	hSpCas9	negative selection	10932793
32543985	32544008	9	+	28162770	PL21	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	-0.4535356363158504	[257]	[81]	-3	hSpCas9	negative selection	10932794
32542381	32542404	9	-	28162770	PL21	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	0.8723349532652886	[368]	[293]	7	hSpCas9	negative selection	10932795
32542144	32542167	9	-	28162770	PL21	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	-1.1010299202312446	[68]	[13]	-6	hSpCas9	negative selection	10932796
32543903	32543926	9	-	28162770	PL21	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	-0.32947985238806093	[178]	[61]	-2	hSpCas9	negative selection	10932797
32543277	32543300	9	+	28162770	PL21	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	0.5400979969736568	[492]	[311]	5	hSpCas9	negative selection	10932798
32543167	32543190	9	-	28162770	PL21	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	-0.5527675235459075	[363]	[107]	-4	hSpCas9	negative selection	10932799
32543887	32543910	9	+	28162770	P31FUJ	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.15526824726419597	[566]	[741]	1	hSpCas9	negative selection	11102156
32543029	32543052	9	+	28162770	P31FUJ	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	0.46993175493252815	[434]	[707]	5	hSpCas9	negative selection	11102157
32543821	32543844	9	+	28162770	P31FUJ	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.710335458629945	[206]	[397]	7	hSpCas9	negative selection	11102158
32542359	32542382	9	-	28162770	P31FUJ	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	0.895521892561161	[85]	[187]	8	hSpCas9	negative selection	11102159
32543985	32544008	9	+	28162770	P31FUJ	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.4940480456597692	[228]	[378]	5	hSpCas9	negative selection	11102160
32542381	32542404	9	-	28162770	P31FUJ	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	0.5296053115892508	[325]	[552]	6	hSpCas9	negative selection	11102161
32542144	32542167	9	-	28162770	P31FUJ	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	0.7596641229002138	[95]	[190]	8	hSpCas9	negative selection	11102162
32543903	32543926	9	-	28162770	P31FUJ	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	0.5441553652087165	[184]	[316]	6	hSpCas9	negative selection	11102163
32543277	32543300	9	+	28162770	P31FUJ	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	0.5907629448244847	[707]	[1252]	6	hSpCas9	negative selection	11102164
32543167	32543190	9	-	28162770	P31FUJ	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	0.09369862026280784	[440]	[552]	0	hSpCas9	negative selection	11102165
32543887	32543910	9	+	28162770	OCIAML5	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.0817810941310757	[356]	[681]	0	hSpCas9	negative selection	11271522
32543029	32543052	9	+	28162770	OCIAML5	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	0.6423441721495347	[262]	[740]	5	hSpCas9	negative selection	11271523
32543821	32543844	9	+	28162770	OCIAML5	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	1.7413081696733594	[56]	[343]	9	hSpCas9	negative selection	11271524
32542359	32542382	9	-	28162770	OCIAML5	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	-0.07245663928929724	[59]	[102]	0	hSpCas9	negative selection	11271525
32543985	32544008	9	+	28162770	OCIAML5	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.4274829217528136	[151]	[368]	3	hSpCas9	negative selection	11271526
32542381	32542404	9	-	28162770	OCIAML5	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	0.546482805626278	[230]	[608]	5	hSpCas9	negative selection	11271527
32542144	32542167	9	-	28162770	OCIAML5	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	0.8653462258808089	[51]	[170]	7	hSpCas9	negative selection	11271528
32543903	32543926	9	-	28162770	OCIAML5	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	0.06898208774118098	[168]	[319]	0	hSpCas9	negative selection	11271529
32543277	32543300	9	+	28162770	OCIAML5	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	0.9023087015618381	[312]	[1055]	7	hSpCas9	negative selection	11271530
32543167	32543190	9	-	28162770	OCIAML5	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	0.3211530084907488	[242]	[547]	2	hSpCas9	negative selection	11271531
32543887	32543910	9	+	28162770	EOL1	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.06549567650658905	[1178]	[649]	0	hSpCas9	negative selection	11440888
32543029	32543052	9	+	28162770	EOL1	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	0.16270750876529927	[506]	[298]	1	hSpCas9	negative selection	11440889
32543821	32543844	9	+	28162770	EOL1	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.10368091979538321	[294]	[166]	0	hSpCas9	negative selection	11440890
32542359	32542382	9	-	28162770	EOL1	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	-0.4697311675415118	[183]	[69]	-3	hSpCas9	negative selection	11440891
32543985	32544008	9	+	28162770	EOL1	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.38121236637229194	[426]	[292]	3	hSpCas9	negative selection	11440892
32542381	32542404	9	-	28162770	EOL1	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	0.4292880737976106	[794]	[563]	4	hSpCas9	negative selection	11440893
32542144	32542167	9	-	28162770	EOL1	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	0.5547911515925571	[114]	[88]	5	hSpCas9	negative selection	11440894
32543903	32543926	9	-	28162770	EOL1	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	-0.7686676198026449	[248]	[76]	-5	hSpCas9	negative selection	11440895
32543277	32543300	9	+	28162770	EOL1	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	0.2170320885654149	[791]	[484]	2	hSpCas9	negative selection	11440896
32543167	32543190	9	-	28162770	EOL1	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	0.14164589323746957	[467]	[271]	1	hSpCas9	negative selection	11440897
32543887	32543910	9	+	28162770	MOLM13	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.4224066117505705	[869]	[842]	3	hSpCas9	negative selection	11610254
32543029	32543052	9	+	28162770	MOLM13	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	0.3204918627718434	[555]	[501]	2	hSpCas9	negative selection	11610255
32543821	32543844	9	+	28162770	MOLM13	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.4951623116946825	[261]	[266]	3	hSpCas9	negative selection	11610256
32542359	32542382	9	-	28162770	MOLM13	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	0.3222119263489437	[176]	[159]	2	hSpCas9	negative selection	11610257
32543985	32544008	9	+	28162770	MOLM13	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.6571597327063182	[320]	[365]	5	hSpCas9	negative selection	11610258
32542381	32542404	9	-	28162770	MOLM13	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	1.3981517264976073	[497]	[948]	9	hSpCas9	negative selection	11610259
32542144	32542167	9	-	28162770	MOLM13	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	0.14596128665721642	[124]	[99]	1	hSpCas9	negative selection	11610260
32543903	32543926	9	-	28162770	MOLM13	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	0.11515523987604165	[354]	[277]	0	hSpCas9	negative selection	11610261
32543277	32543300	9	+	28162770	MOLM13	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	0.4177762667167755	[702]	[678]	3	hSpCas9	negative selection	11610262
32543167	32543190	9	-	28162770	MOLM13	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	0.5641046968038819	[637]	[681]	4	hSpCas9	negative selection	11610263
32543887	32543910	9	+	28162770	HEL	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	-2.4021577059739663	[717]	[86]	-8	hSpCas9	negative selection	11779620
32543029	32543052	9	+	28162770	HEL	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	-1.1810700221136061	[484]	[136]	-6	hSpCas9	negative selection	11779621
32543821	32543844	9	+	28162770	HEL	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	-0.5098602932816727	[268]	[120]	-3	hSpCas9	negative selection	11779622
32542359	32542382	9	-	28162770	HEL	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	-1.565369363329843	[133]	[28]	-7	hSpCas9	negative selection	11779623
32543985	32544008	9	+	28162770	HEL	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	-2.2438793685819007	[317]	[42]	-8	hSpCas9	negative selection	11779624
32542381	32542404	9	-	28162770	HEL	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	-0.2973482665823216	[565]	[294]	-2	hSpCas9	negative selection	11779625
32542144	32542167	9	-	28162770	HEL	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	0.3006328551753643	[89]	[70]	2	hSpCas9	negative selection	11779626
32543903	32543926	9	-	28162770	HEL	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	-2.169401152622624	[301]	[42]	-8	hSpCas9	negative selection	11779627
32543277	32543300	9	+	28162770	HEL	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	-1.4407845235619263	[639]	[150]	-7	hSpCas9	negative selection	11779628
32543167	32543190	9	-	28162770	HEL	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	-1.8718343408294014	[439]	[76]	-7	hSpCas9	negative selection	11779629
32543887	32543910	9	+	28162770	MV411	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.388495137666103	[515]	[568]	3	hSpCas9	negative selection	11948986
32543029	32543052	9	+	28162770	MV411	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	1.0223101617250885	[307]	[526]	8	hSpCas9	negative selection	11948987
32543821	32543844	9	+	28162770	MV411	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	-0.2724299217164958	[194]	[135]	-2	hSpCas9	negative selection	11948988
32542359	32542382	9	-	28162770	MV411	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	0.09719491520216283	[90]	[81]	0	hSpCas9	negative selection	11948989
32543985	32544008	9	+	28162770	MV411	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.23570825820066815	[246]	[244]	2	hSpCas9	negative selection	11948990
32542381	32542404	9	-	28162770	MV411	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	0.8836581712091646	[340]	[529]	7	hSpCas9	negative selection	11948991
32542144	32542167	9	-	28162770	MV411	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	-0.4306343543298623	[71]	[44]	-3	hSpCas9	negative selection	11948992
32543903	32543926	9	-	28162770	MV411	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	1.0331357167726238	[162]	[280]	8	hSpCas9	negative selection	11948993
32543277	32543300	9	+	28162770	MV411	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	0.2761203054868602	[497]	[507]	2	hSpCas9	negative selection	11948994
32543167	32543190	9	-	28162770	MV411	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	-0.5541272830713153	[372]	[213]	-4	hSpCas9	negative selection	11948995
32543887	32543910	9	+	28162770	MONOMAC1	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	0.794925833875028	[449]	[894]	7	hSpCas9	negative selection	12118352
32543029	32543052	9	+	28162770	MONOMAC1	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	0.1768433274625305	[239]	[310]	1	hSpCas9	negative selection	12118353
32543821	32543844	9	+	28162770	MONOMAC1	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.3402289116303062	[81]	[118]	3	hSpCas9	negative selection	12118354
32542359	32542382	9	-	28162770	MONOMAC1	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	0.8264221257644353	[60]	[123]	7	hSpCas9	negative selection	12118355
32543985	32544008	9	+	28162770	MONOMAC1	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.16647035157920814	[170]	[219]	1	hSpCas9	negative selection	12118356
32542381	32542404	9	-	28162770	MONOMAC1	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	0.9706905986785128	[218]	[491]	8	hSpCas9	negative selection	12118357
32542144	32542167	9	-	28162770	MONOMAC1	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	0.9024988264913606	[41]	[89]	8	hSpCas9	negative selection	12118358
32543903	32543926	9	-	28162770	MONOMAC1	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	0.4840127578529795	[120]	[193]	5	hSpCas9	negative selection	12118359
32543277	32543300	9	+	28162770	MONOMAC1	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	0.5059814151833149	[300]	[489]	5	hSpCas9	negative selection	12118360
32543167	32543190	9	-	28162770	MONOMAC1	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	1.2398270146724686	[204]	[554]	9	hSpCas9	negative selection	12118361
32543887	32543910	9	+	28162770	OCIAML2	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	-0.2137215222052089	[117]	[563]	-2	hSpCas9	negative selection	12287718
32543029	32543052	9	+	28162770	OCIAML2	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	0.5764940868718645	[63]	[528]	5	hSpCas9	negative selection	12287719
32543821	32543844	9	+	28162770	OCIAML2	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.8639720996803116	[33]	[342]	8	hSpCas9	negative selection	12287720
32542359	32542382	9	-	28162770	OCIAML2	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	-0.7050950788791841	[29]	[101]	-5	hSpCas9	negative selection	12287721
32543985	32544008	9	+	28162770	OCIAML2	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.03526110448779607	[49]	[283]	0	hSpCas9	negative selection	12287722
32542381	32542404	9	-	28162770	OCIAML2	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	-0.20759541940836712	[84]	[407]	-2	hSpCas9	negative selection	12287723
32542144	32542167	9	-	28162770	OCIAML2	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	1.9888017933951359	[7]	[175]	9	hSpCas9	negative selection	12287724
32543903	32543926	9	-	28162770	OCIAML2	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	0.39535282678615147	[30]	[225]	4	hSpCas9	negative selection	12287725
32543277	32543300	9	+	28162770	OCIAML2	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	-0.27900975270052975	[87]	[401]	-2	hSpCas9	negative selection	12287726
32543167	32543190	9	-	28162770	OCIAML2	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	0.050202338059279206	[68]	[395]	0	hSpCas9	negative selection	12287727
32543887	32543910	9	+	28162770	OCIAML3	viability	AACAGTACTCCACTATCCGGTGG	TOPORS	ENSG00000197579	-0.46982822910343347	[177]	[387]	-4	hSpCas9	negative selection	12457084
32543029	32543052	9	+	28162770	OCIAML3	viability	GAGGACAGTTCAACAAGTTCTGG	TOPORS	ENSG00000197579	0.5094219493312426	[73]	[317]	5	hSpCas9	negative selection	12457085
32543821	32543844	9	+	28162770	OCIAML3	viability	GCAATCTGTCTCATAAACTGAGG	TOPORS	ENSG00000197579	0.290515142255901	[38]	[143]	2	hSpCas9	negative selection	12457086
32542359	32542382	9	-	28162770	OCIAML3	viability	GGTACGAATCATCTTACAGGAGG	TOPORS	ENSG00000197579	-0.1651643415202888	[38]	[104]	-1	hSpCas9	negative selection	12457087
32543985	32544008	9	+	28162770	OCIAML3	viability	GTAGCGAAATCGTCGATCAGGGG	TOPORS	ENSG00000197579	0.10113777814741592	[62]	[203]	1	hSpCas9	negative selection	12457088
32542381	32542404	9	-	28162770	OCIAML3	viability	AGTAGAAACAAGGACAGGGATGG	TOPORS	ENSG00000197579	0.7279204545631991	[91]	[459]	6	hSpCas9	negative selection	12457089
32542144	32542167	9	-	28162770	OCIAML3	viability	GTGAGAAATGAAAAGCCTGGAGG	TOPORS	ENSG00000197579	-0.4420045468791133	[26]	[59]	-3	hSpCas9	negative selection	12457090
32543903	32543926	9	-	28162770	OCIAML3	viability	CAGAAGAACAACAACTCCACCGG	TOPORS	ENSG00000197579	-0.1414954356266565	[56]	[155]	-1	hSpCas9	negative selection	12457091
32543277	32543300	9	+	28162770	OCIAML3	viability	CCATGGTGCCTGACTAACAGTGG	TOPORS	ENSG00000197579	0.6581582490641533	[160]	[766]	6	hSpCas9	negative selection	12457092
32543167	32543190	9	-	28162770	OCIAML3	viability	GATGAAGAACTTGTCACAGGAGG	TOPORS	ENSG00000197579	0.16918949541522244	[108]	[369]	1	hSpCas9	negative selection	12457093