Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:89910
• Symbol:UBE3B
• Description:ubiquitin protein ligase E3B

DataSource: http://genomecrispr.dkfz.de/#!/results/UBE3B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
109486484	109486507	12	-	26472758	Jiyoye	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.47253038477641474	[183]	[99]	-3	hSpCas9	negative selection	176552
109486554	109486577	12	+	26472758	Jiyoye	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	-2.5928246184941264	[47]	[5]	-9	hSpCas9	negative selection	176553
109486508	109486531	12	-	26472758	Jiyoye	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-0.34330501913481437	[142]	[84]	-2	hSpCas9	negative selection	176554
109489977	109490000	12	-	26472758	Jiyoye	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	0.6481834810096682	[76]	[90]	5	hSpCas9	negative selection	176555
109483623	109483646	12	+	26472758	Jiyoye	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	1.5540167698351446	[41]	[92]	8	hSpCas9	negative selection	176556
109488627	109488650	12	+	26472758	Jiyoye	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.5021237855611362	[146]	[156]	4	hSpCas9	negative selection	176557
109483659	109483682	12	-	26472758	Jiyoye	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	0.731797585562499	[106]	[133]	5	hSpCas9	negative selection	176558
109483671	109483694	12	-	26472758	Jiyoye	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	0.009839883960488516	[53]	[40]	0	hSpCas9	negative selection	176559
109486050	109486073	12	+	26472758	Jiyoye	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	-0.7199365363974659	[248]	[113]	-5	hSpCas9	negative selection	176560
109488592	109488615	12	-	26472758	Jiyoye	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	-0.4895139012518307	[228]	[122]	-4	hSpCas9	negative selection	176561
109486484	109486507	12	-	26472758	KBM7	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.5564085408761501	[449,296]	[270,238]	6	hSpCas9	negative selection	367670
109486554	109486577	12	+	26472758	KBM7	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	0.2785793646143535	[51,111]	[62,35]	3	hSpCas9	negative selection	367671
109486508	109486531	12	-	26472758	KBM7	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-0.9464673139349655	[682,449]	[192,84]	-6	hSpCas9	negative selection	367672
109489977	109490000	12	-	26472758	KBM7	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-0.3807074353203226	[312,129]	[76,76]	-3	hSpCas9	negative selection	367673
109483623	109483646	12	+	26472758	KBM7	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	-0.4750996688761755	[162,235]	[95,44]	-4	hSpCas9	negative selection	367674
109488627	109488650	12	+	26472758	KBM7	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.5478979009601554	[523,511]	[387,329]	6	hSpCas9	negative selection	367675
109483659	109483682	12	-	26472758	KBM7	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	0.6784762649991883	[457,363]	[303,309]	7	hSpCas9	negative selection	367676
109483671	109483694	12	-	26472758	KBM7	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	0.2649515603242303	[160,171]	[144,49]	2	hSpCas9	negative selection	367677
109486050	109486073	12	+	26472758	KBM7	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	-0.00886542559991077	[898,703]	[414,332]	0	hSpCas9	negative selection	367678
109488592	109488615	12	-	26472758	KBM7	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	-0.020623654843611283	[1028,892]	[474,416]	0	hSpCas9	negative selection	367679
109486484	109486507	12	-	26472758	Raji	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.48353202125884853	[187]	[60]	4	hSpCas9	negative selection	558788
109486554	109486577	12	+	26472758	Raji	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	1.0111682201142962	[61]	[28]	8	hSpCas9	negative selection	558789
109486508	109486531	12	-	26472758	Raji	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-1.7369655941662059	[315]	[21]	-8	hSpCas9	negative selection	558790
109489977	109490000	12	-	26472758	Raji	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	0.17846663343508196	[98]	[25]	1	hSpCas9	negative selection	558791
109483623	109483646	12	+	26472758	Raji	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	2.171513872793315	[43]	[45]	9	hSpCas9	negative selection	558792
109488627	109488650	12	+	26472758	Raji	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.5598957400711062	[227]	[77]	5	hSpCas9	negative selection	558793
109483659	109483682	12	-	26472758	Raji	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	0.7211050290761796	[297]	[113]	6	hSpCas9	negative selection	558794
109483671	109483694	12	-	26472758	Raji	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	-0.004825968212425535	[146]	[33]	0	hSpCas9	negative selection	558795
109486050	109486073	12	+	26472758	Raji	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	0.16160392637148613	[469]	[121]	1	hSpCas9	negative selection	558796
109488592	109488615	12	-	26472758	Raji	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	-0.6732265314514758	[480]	[69]	-5	hSpCas9	negative selection	558797
109486484	109486507	12	-	26472758	K562	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.18367492443784328	[295]	[219]	-1	hSpCas9	negative selection	749906
109486554	109486577	12	+	26472758	K562	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	0.32327414837768664	[88]	[93]	2	hSpCas9	negative selection	749907
109486508	109486531	12	-	26472758	K562	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-2.501925198815621	[462]	[68]	-8	hSpCas9	negative selection	749908
109489977	109490000	12	-	26472758	K562	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-1.5827446754713375	[219]	[61]	-7	hSpCas9	negative selection	749909
109483623	109483646	12	+	26472758	K562	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	-0.04969398935279057	[243]	[198]	0	hSpCas9	negative selection	749910
109488627	109488650	12	+	26472758	K562	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	-0.6448778079273336	[488]	[263]	-4	hSpCas9	negative selection	749911
109483659	109483682	12	-	26472758	K562	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	1.1216756629542073	[422]	[776]	8	hSpCas9	negative selection	749912
109483671	109483694	12	-	26472758	K562	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	0.4066901565653239	[167]	[187]	3	hSpCas9	negative selection	749913
109486050	109486073	12	+	26472758	K562	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	0.8085927557164582	[465]	[688]	6	hSpCas9	negative selection	749914
109488592	109488615	12	-	26472758	K562	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	0.1963860312446455	[793]	[767]	1	hSpCas9	negative selection	749915
109483560	109483583	12	-	26627737	DLD1	viability	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	1.6372048040290477	[200]	[150,227,206]	9	hSpCas9	negative selection	782074
109486484	109486507	12	-	26627737	DLD1	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.09120131235707207	[104]	[14,21,62]	0	hSpCas9	negative selection	782075
109489963	109489986	12	+	26627737	DLD1	viability	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	0.4432735124511967	[349]	[159,120,161]	4	hSpCas9	negative selection	782076
109490548	109490571	12	+	26627737	DLD1	viability	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	-0.28637129506592174	[245]	[111,29,47]	-3	hSpCas9	negative selection	782077
109491072	109491095	12	-	26627737	DLD1	viability	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	-0.7611196927052315	[287]	[55,42,58]	-6	hSpCas9	negative selection	782078
109499778	109499801	12	-	26627737	DLD1	viability	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.06779604872222744	[720]	[242,104,338]	0	hSpCas9	negative selection	782079
109483560	109483583	12	-	26627737	GBM cells	viability after 5 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.1688760013105496	[276]	[138,194]	2	hSpCas9	negative selection	864389
109486484	109486507	12	-	26627737	GBM cells	viability after 5 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.19957335301939683	[81]	[63,36]	3	hSpCas9	negative selection	864390
109489963	109489986	12	+	26627737	GBM cells	viability after 5 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	-0.21878116778406909	[216]	[73,125]	-3	hSpCas9	negative selection	864391
109490548	109490571	12	+	26627737	GBM cells	viability after 5 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	0.23594886216325628	[113]	[70,72]	3	hSpCas9	negative selection	864392
109491072	109491095	12	-	26627737	GBM cells	viability after 5 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	-0.1573543447610597	[182]	[90,84]	-2	hSpCas9	negative selection	864393
109499778	109499801	12	-	26627737	GBM cells	viability after 5 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	-0.24101638625878952	[475]	[221,209]	-4	hSpCas9	negative selection	864394
109483560	109483583	12	-	26627737	GBM cells	viability after 13 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.4613353577201451	[276]	[271,153]	6	hSpCas9	negative selection	946704
109486484	109486507	12	-	26627737	GBM cells	viability after 13 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.15754631610332148	[81]	[58,41]	2	hSpCas9	negative selection	946705
109489963	109489986	12	+	26627737	GBM cells	viability after 13 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	-0.12465883274793832	[216]	[91,120]	-1	hSpCas9	negative selection	946706
109490548	109490571	12	+	26627737	GBM cells	viability after 13 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	0.20670866131450016	[113]	[77,65]	2	hSpCas9	negative selection	946707
109491072	109491095	12	-	26627737	GBM cells	viability after 13 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	-0.30360257089866605	[182]	[80,79]	-4	hSpCas9	negative selection	946708
109499778	109499801	12	-	26627737	GBM cells	viability after 13 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	-0.3279144622618223	[475]	[202,207]	-4	hSpCas9	negative selection	946709
109483560	109483583	12	-	26627737	GBM cells	viability after 21 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.5477779818651797	[276]	[231,208]	5	hSpCas9	negative selection	1029019
109486484	109486507	12	-	26627737	GBM cells	viability after 21 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.5612345357669679	[81]	[71,59]	6	hSpCas9	negative selection	1029020
109489963	109489986	12	+	26627737	GBM cells	viability after 21 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	0.16295474244177188	[216]	[143,120]	1	hSpCas9	negative selection	1029021
109490548	109490571	12	+	26627737	GBM cells	viability after 21 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	-0.07218885601149916	[113]	[60,56]	0	hSpCas9	negative selection	1029022
109491072	109491095	12	-	26627737	GBM cells	viability after 21 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	0.04056887818258992	[182]	[107,96]	0	hSpCas9	negative selection	1029023
109499778	109499801	12	-	26627737	GBM cells	viability after 21 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	-0.07402615531837164	[475]	[276,216]	0	hSpCas9	negative selection	1029024
109483560	109483583	12	-	26627737	RPE1	viability after 9 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.606653509752817	[672]	[143,548]	4	hSpCas9	negative selection	1111334
109486484	109486507	12	-	26627737	RPE1	viability after 9 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.47298592749123464	[616]	[98,190]	-3	hSpCas9	negative selection	1111335
109489963	109489986	12	+	26627737	RPE1	viability after 9 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	1.5705659099380087	[693]	[533,788]	8	hSpCas9	negative selection	1111336
109490548	109490571	12	+	26627737	RPE1	viability after 9 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	1.5651253770408025	[118]	[42,196]	8	hSpCas9	negative selection	1111337
109491072	109491095	12	-	26627737	RPE1	viability after 9 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	-0.09933640598695725	[230]	[101,22]	0	hSpCas9	negative selection	1111338
109499778	109499801	12	-	26627737	RPE1	viability after 9 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	1.3137902665244168	[415]	[328,316]	7	hSpCas9	negative selection	1111339
109483560	109483583	12	-	26627737	RPE1	viability after 12 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.6362217197139366	[672]	[230,333]	4	hSpCas9	negative selection	1193649
109486484	109486507	12	-	26627737	RPE1	viability after 12 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-1.3199039310167175	[616]	[96,33]	-7	hSpCas9	negative selection	1193650
109489963	109489986	12	+	26627737	RPE1	viability after 12 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	1.5758157446151195	[693]	[566,543]	8	hSpCas9	negative selection	1193651
109490548	109490571	12	+	26627737	RPE1	viability after 12 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	1.5413386358161312	[118]	[94,90]	8	hSpCas9	negative selection	1193652
109491072	109491095	12	-	26627737	RPE1	viability after 12 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	0.11965049756131729	[230]	[98,33]	0	hSpCas9	negative selection	1193653
109499778	109499801	12	-	26627737	RPE1	viability after 12 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.6166544834558194	[415]	[149,193]	4	hSpCas9	negative selection	1193654
109483560	109483583	12	-	26627737	RPE1	viability after 15 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.9149625484068161	[672]	[304,410]	5	hSpCas9	negative selection	1275964
109486484	109486507	12	-	26627737	RPE1	viability after 15 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.6130569149904006	[616]	[163,65]	-4	hSpCas9	negative selection	1275965
109489963	109489986	12	+	26627737	RPE1	viability after 15 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	2.107440008684546	[693]	[846,844]	8	hSpCas9	negative selection	1275966
109490548	109490571	12	+	26627737	RPE1	viability after 15 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	2.240758063433671	[118]	[96,218]	9	hSpCas9	negative selection	1275967
109491072	109491095	12	-	26627737	RPE1	viability after 15 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	-0.14415198749753166	[230]	[107,11]	-1	hSpCas9	negative selection	1275968
109499778	109499801	12	-	26627737	RPE1	viability after 15 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.6922638033309284	[415]	[181,197]	4	hSpCas9	negative selection	1275969
109483560	109483583	12	-	26627737	RPE1	viability after 18 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.6191062986109974	[672]	[233,326]	4	hSpCas9	negative selection	1358279
109486484	109486507	12	-	26627737	RPE1	viability after 18 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-1.5499310519689942	[616]	[52,60]	-7	hSpCas9	negative selection	1358280
109489963	109489986	12	+	26627737	RPE1	viability after 18 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	2.2530252050752075	[693]	[754,1039]	9	hSpCas9	negative selection	1358281
109490548	109490571	12	+	26627737	RPE1	viability after 18 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	2.436103295799993	[118]	[94,257]	9	hSpCas9	negative selection	1358282
109491072	109491095	12	-	26627737	RPE1	viability after 18 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	0.17295372183842894	[230]	[92,45]	1	hSpCas9	negative selection	1358283
109499778	109499801	12	-	26627737	RPE1	viability after 18 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	1.037806986579685	[415]	[273,183]	6	hSpCas9	negative selection	1358284
109483560	109483583	12	-	26627737	HeLa	viability after 8 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	-0.5082631294991771	[471]	[155,64,209]	-5	hSpCas9	negative selection	1440594
109486484	109486507	12	-	26627737	HeLa	viability after 8 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.7288468941409463	[182]	[35,64,40]	-6	hSpCas9	negative selection	1440595
109489963	109489986	12	+	26627737	HeLa	viability after 8 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	-0.5503291918983966	[568]	[193,79,233]	-5	hSpCas9	negative selection	1440596
109490548	109490571	12	+	26627737	HeLa	viability after 8 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	0.694435932161794	[135]	[152,111,38]	6	hSpCas9	negative selection	1440597
109491072	109491095	12	-	26627737	HeLa	viability after 8 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	-0.1921243920275802	[280]	[54,78,170]	-2	hSpCas9	negative selection	1440598
109499778	109499801	12	-	26627737	HeLa	viability after 8 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	-0.17563177338384145	[606]	[311,220,188]	-2	hSpCas9	negative selection	1440599
109483560	109483583	12	-	26627737	HeLa	viability after 12 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.11786328335519725	[471]	[57,244,323]	1	hSpCas9	negative selection	1522909
109486484	109486507	12	-	26627737	HeLa	viability after 12 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.36563926083601794	[182]	[76,73,23]	-3	hSpCas9	negative selection	1522910
109489963	109489986	12	+	26627737	HeLa	viability after 12 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	-0.32760421877993706	[568]	[254,244,57]	-3	hSpCas9	negative selection	1522911
109490548	109490571	12	+	26627737	HeLa	viability after 12 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	0.9394168203403824	[135]	[147,74,104]	7	hSpCas9	negative selection	1522912
109491072	109491095	12	-	26627737	HeLa	viability after 12 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	0.3380805156502825	[280]	[76,168,189]	3	hSpCas9	negative selection	1522913
109499778	109499801	12	-	26627737	HeLa	viability after 12 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	-0.47015375664113274	[606]	[153,194,191]	-4	hSpCas9	negative selection	1522914
109483560	109483583	12	-	26627737	HeLa	viability after 15 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	-0.2822518947569249	[471]	[91,162,224]	-2	hSpCas9	negative selection	1605224
109486484	109486507	12	-	26627737	HeLa	viability after 15 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.5463283175089866	[182]	[67,79,0]	-5	hSpCas9	negative selection	1605225
109489963	109489986	12	+	26627737	HeLa	viability after 15 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	-0.6576581393917424	[568]	[31,238,172]	-5	hSpCas9	negative selection	1605226
109490548	109490571	12	+	26627737	HeLa	viability after 15 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	1.54929888890391	[135]	[157,119,211]	8	hSpCas9	negative selection	1605227
109491072	109491095	12	-	26627737	HeLa	viability after 15 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	0.5468005194324204	[280]	[74,133,303]	4	hSpCas9	negative selection	1605228
109499778	109499801	12	-	26627737	HeLa	viability after 15 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.09069285124469584	[606]	[134,393,261]	0	hSpCas9	negative selection	1605229
109483560	109483583	12	-	26627737	HeLa	viability after 18 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	-0.27711436938183465	[471]	[65,130,224]	-2	hSpCas9	negative selection	1687539
109486484	109486507	12	-	26627737	HeLa	viability after 18 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.45915815688265016	[182]	[51,65,0]	-4	hSpCas9	negative selection	1687540
109489963	109489986	12	+	26627737	HeLa	viability after 18 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	-0.6305849312409346	[568]	[21,203,172]	-5	hSpCas9	negative selection	1687541
109490548	109490571	12	+	26627737	HeLa	viability after 18 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	1.5154772539079218	[135]	[98,98,211]	8	hSpCas9	negative selection	1687542
109491072	109491095	12	-	26627737	HeLa	viability after 18 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	0.5276477920822105	[280]	[49,105,303]	4	hSpCas9	negative selection	1687543
109499778	109499801	12	-	26627737	HeLa	viability after 18 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.11147228247004481	[606]	[94,329,261]	1	hSpCas9	negative selection	1687544
109483560	109483583	12	-	26627737	HCT116	viability after 6 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	1.703994378712024	[592]	[81,425]	8	hSpCas9	negative selection	1769854
109486484	109486507	12	-	26627737	HCT116	viability after 6 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.6525995479564928	[193]	[123,5]	3	hSpCas9	negative selection	1769855
109489963	109489986	12	+	26627737	HCT116	viability after 6 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	-0.11342183035715564	[515]	[161,26]	0	hSpCas9	negative selection	1769856
109490548	109490571	12	+	26627737	HCT116	viability after 6 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	-0.9661233292389144	[242]	[25,15]	-5	hSpCas9	negative selection	1769857
109491072	109491095	12	-	26627737	HCT116	viability after 6 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	0.4403826222353487	[608]	[243,66]	2	hSpCas9	negative selection	1769858
109499778	109499801	12	-	26627737	HCT116	viability after 6 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.738433287775266	[800]	[231,197]	4	hSpCas9	negative selection	1769859
109483560	109483583	12	-	26627737	HCT116	viability after 8 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.6096923351495499	[215]	[216,188,139]	6	hSpCas9	negative selection	1852169
109486484	109486507	12	-	26627737	HCT116	viability after 8 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-1.2553871802416108	[155]	[40,21,44]	-9	hSpCas9	negative selection	1852170
109489963	109489986	12	+	26627737	HCT116	viability after 8 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	1.1250130612295175	[132]	[149,140,187]	8	hSpCas9	negative selection	1852171
109490548	109490571	12	+	26627737	HCT116	viability after 8 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	0.2404331198650883	[133]	[99,81,79]	2	hSpCas9	negative selection	1852172
109491072	109491095	12	-	26627737	HCT116	viability after 8 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	0.5252404919014636	[130]	[129,67,113]	5	hSpCas9	negative selection	1852173
109499778	109499801	12	-	26627737	HCT116	viability after 8 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	-0.29284797234181587	[443]	[169,261,166]	-3	hSpCas9	negative selection	1852174
109483560	109483583	12	-	26627737	HCT116	viability after 9 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.06782772734532411	[592]	[27,274]	0	hSpCas9	negative selection	1934484
109486484	109486507	12	-	26627737	HCT116	viability after 9 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-2.037097656752947	[193]	[20,5]	-8	hSpCas9	negative selection	1934485
109489963	109489986	12	+	26627737	HCT116	viability after 9 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	0.8513613888085094	[515]	[56,399]	6	hSpCas9	negative selection	1934486
109490548	109490571	12	+	26627737	HCT116	viability after 9 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	0.5274192459098161	[242]	[140,55]	4	hSpCas9	negative selection	1934487
109491072	109491095	12	-	26627737	HCT116	viability after 9 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	-0.5095711295743459	[608]	[154,81]	-4	hSpCas9	negative selection	1934488
109499778	109499801	12	-	26627737	HCT116	viability after 9 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.945674163856322	[800]	[564,290]	6	hSpCas9	negative selection	1934489
109483560	109483583	12	-	26627737	HCT116	viability after 12 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.5421568211850735	[215]	[170,190,133]	5	hSpCas9	negative selection	2016799
109486484	109486507	12	-	26627737	HCT116	viability after 12 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.35777838263239936	[155]	[83,56,48]	-4	hSpCas9	negative selection	2016800
109489963	109489986	12	+	26627737	HCT116	viability after 12 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	0.8675843013945678	[132]	[155,164,59]	7	hSpCas9	negative selection	2016801
109490548	109490571	12	+	26627737	HCT116	viability after 12 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	0.7354964570811307	[133]	[56,156,143]	6	hSpCas9	negative selection	2016802
109491072	109491095	12	-	26627737	HCT116	viability after 12 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	-0.10609459284282985	[130]	[27,61,104]	-1	hSpCas9	negative selection	2016803
109499778	109499801	12	-	26627737	HCT116	viability after 12 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	-0.11855993121890307	[443]	[186,287,173]	-1	hSpCas9	negative selection	2016804
109483560	109483583	12	-	26627737	HCT116	viability after 15 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.06315528140138155	[215]	[122,135,128]	0	hSpCas9	negative selection	2099114
109486484	109486507	12	-	26627737	HCT116	viability after 15 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.027710982573133314	[155]	[166,8,106]	0	hSpCas9	negative selection	2099115
109489963	109489986	12	+	26627737	HCT116	viability after 15 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	1.1676264673422652	[132]	[191,216,108]	8	hSpCas9	negative selection	2099116
109490548	109490571	12	+	26627737	HCT116	viability after 15 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	0.5674251680579186	[133]	[72,139,123]	5	hSpCas9	negative selection	2099117
109491072	109491095	12	-	26627737	HCT116	viability after 15 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	-0.5422362630726916	[130]	[53,26,73]	-5	hSpCas9	negative selection	2099118
109499778	109499801	12	-	26627737	HCT116	viability after 15 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.12570299901855297	[443]	[398,229,220]	1	hSpCas9	negative selection	2099119
109483560	109483583	12	-	26627737	HCT116	viability after 18 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.1676550412793985	[215]	[45,136,169]	1	hSpCas9	negative selection	2181429
109486484	109486507	12	-	26627737	HCT116	viability after 18 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-1.3469378014541311	[155]	[41,6,41]	-8	hSpCas9	negative selection	2181430
109489963	109489986	12	+	26627737	HCT116	viability after 18 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	1.103785750789408	[132]	[161,158,89]	8	hSpCas9	negative selection	2181431
109490548	109490571	12	+	26627737	HCT116	viability after 18 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	-0.544493439304309	[133]	[48,18,67]	-5	hSpCas9	negative selection	2181432
109491072	109491095	12	-	26627737	HCT116	viability after 18 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	-0.46981443528798694	[130]	[78,7,52]	-4	hSpCas9	negative selection	2181433
109499778	109499801	12	-	26627737	HCT116	viability after 18 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.3206581542797967	[443]	[323,289,184]	2	hSpCas9	negative selection	2181434
109483559	109483582	12	-	24336569	HL60	viability	TGCTCTCGAGGTCTGAGACAGGG	UBE3B	ENSG00000151148	-0.4253326092471258	[322]	[508]	-4	hSpCas9	negative selection	2304789
109483571	109483594	12	-	24336569	HL60	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.10326847094724485	[499]	[984]	-1	hSpCas9	negative selection	2304790
109483584	109483607	12	+	24336569	HL60	viability	GTTCATCGATAGAGCCCGTCAGG	UBE3B	ENSG00000151148	-0.881463435281146	[268]	[308]	-7	hSpCas9	negative selection	2304791
109483598	109483621	12	+	24336569	HL60	viability	CCCGTCAGGCACGAGAAGAAAGG	UBE3B	ENSG00000151148	-0.17876130198381124	[712]	[1332]	-1	hSpCas9	negative selection	2304792
109483611	109483634	12	+	24336569	HL60	viability	AGAAGAAAGGCTTGTGCAGAAGG	UBE3B	ENSG00000151148	-0.6259475319949821	[737]	[1011]	-5	hSpCas9	negative selection	2304793
109483616	109483639	12	+	24336569	HL60	viability	AAAGGCTTGTGCAGAAGGAACGG	UBE3B	ENSG00000151148	-0.23720959575976308	[771]	[1385]	-2	hSpCas9	negative selection	2304794
109483622	109483645	12	+	24336569	HL60	viability	TTGTGCAGAAGGAACGGGAGCGG	UBE3B	ENSG00000151148	0.3793006723070764	[884]	[2435]	3	hSpCas9	negative selection	2304795
109483641	109483664	12	+	24336569	HL60	viability	GCGGGCAGCTGTTGTGATCCAGG	UBE3B	ENSG00000151148	0.5757432845621395	[369]	[1166]	5	hSpCas9	negative selection	2304796
109483652	109483675	12	+	24336569	HL60	viability	TTGTGATCCAGGCCCATGTCCGG	UBE3B	ENSG00000151148	0.11493311217460733	[1223]	[2804]	1	hSpCas9	negative selection	2304797
109483691	109483714	12	+	24336569	HL60	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.17646061456464324	[509]	[954]	-1	hSpCas9	negative selection	2304798
109483559	109483582	12	-	24336569	KBM7	viability	TGCTCTCGAGGTCTGAGACAGGG	UBE3B	ENSG00000151148	-1.134079723732101	[308]	[383]	-7	hSpCas9	negative selection	2371966
109483571	109483594	12	-	24336569	KBM7	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.3382023135603698	[461]	[1592]	3	hSpCas9	negative selection	2371967
109483584	109483607	12	+	24336569	KBM7	viability	GTTCATCGATAGAGCCCGTCAGG	UBE3B	ENSG00000151148	0.6484400159882651	[177]	[760]	6	hSpCas9	negative selection	2371968
109483598	109483621	12	+	24336569	KBM7	viability	CCCGTCAGGCACGAGAAGAAAGG	UBE3B	ENSG00000151148	1.5244064272815212	[350]	[2753]	9	hSpCas9	negative selection	2371969
109483611	109483634	12	+	24336569	KBM7	viability	AGAAGAAAGGCTTGTGCAGAAGG	UBE3B	ENSG00000151148	-0.3142703187948598	[500]	[1098]	-3	hSpCas9	negative selection	2371970
109483616	109483639	12	+	24336569	KBM7	viability	AAAGGCTTGTGCAGAAGGAACGG	UBE3B	ENSG00000151148	1.1707419011187046	[284]	[1749]	8	hSpCas9	negative selection	2371971
109483622	109483645	12	+	24336569	KBM7	viability	TTGTGCAGAAGGAACGGGAGCGG	UBE3B	ENSG00000151148	0.2817987712289276	[895]	[2970]	2	hSpCas9	negative selection	2371972
109483641	109483664	12	+	24336569	KBM7	viability	GCGGGCAGCTGTTGTGATCCAGG	UBE3B	ENSG00000151148	-0.8313074192744947	[470]	[721]	-6	hSpCas9	negative selection	2371973
109483652	109483675	12	+	24336569	KBM7	viability	TTGTGATCCAGGCCCATGTCCGG	UBE3B	ENSG00000151148	0.15328579876490234	[811]	[2462]	1	hSpCas9	negative selection	2371974
109483691	109483714	12	+	24336569	KBM7	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.6598670933448726	[581]	[2507]	6	hSpCas9	negative selection	2371975
109515393	109515416	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTTTCACTCTTGTTGCCCAGG	UBE3B	ENSG00000151148	1.0342323942437988	[48,24]	[15,15]	4	dCas9-VP64	positive selection	2423122
109477455	109477478	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGCTGGAACCCACTCCGGCCGGG	UBE3B	ENSG00000151148	-0.8413614841981174	[141,79]	[12,12]	-5	dCas9-VP64	positive selection	2458991
109477437	109477460	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGTTTTCTTTCCAGCCTCCCCGG	UBE3B	ENSG00000151148	0.17891818774766965	[70,109]	[17,26]	0	dCas9-VP64	positive selection	2458992
109477503	109477526	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGCTGAAATAGCGGAGGTGGG	UBE3B	ENSG00000151148	1.379359068371449	[4,4]	[2,2]	5	dCas9-VP64	positive selection	2458993
109477472	109477495	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCTCCCCAGCCGAGAAAAGCTGG	UBE3B	ENSG00000151148	-1.1847432280637138	[89,55]	[10,1]	-6	dCas9-VP64	positive selection	2463059
109477451	109477474	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAACCCACTCCGGCCGGGGAGG	UBE3B	ENSG00000151148	-1.5621862175401526	[20,92]	[5,0]	-8	dCas9-VP64	positive selection	2463060
109477427	109477450	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGAAAGAAAACTGGCCCCTAGG	UBE3B	ENSG00000151148	-0.4041117994676553	[40,37]	[7,3]	-2	dCas9-VP64	positive selection	2463061
109515393	109515416	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTTTCACTCTTGTTGCCCAGG	UBE3B	ENSG00000151148	1.1207783393058013	[70,52]	[75,13]	7	dCas9-VP64	positive selection	2518377
109477455	109477478	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGCTGGAACCCACTCCGGCCGGG	UBE3B	ENSG00000151148	0.1748038763070944	[102,106]	[48,27]	1	dCas9-VP64	positive selection	2554246
109477437	109477460	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGTTTTCTTTCCAGCCTCCCCGG	UBE3B	ENSG00000151148	-0.7325896514796738	[647,100]	[110,39]	-7	dCas9-VP64	positive selection	2554247
109477503	109477526	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGCTGAAATAGCGGAGGTGGG	UBE3B	ENSG00000151148	0.8137218134574822	[16,44]	[1,30]	5	dCas9-VP64	positive selection	2554248
109477472	109477495	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCTCCCCAGCCGAGAAAAGCTGG	UBE3B	ENSG00000151148	1.0196908548199353	[76,61]	[18,70]	6	dCas9-VP64	positive selection	2558314
109477451	109477474	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAACCCACTCCGGCCGGGGAGG	UBE3B	ENSG00000151148	-0.45371056182123937	[15,1]	[2,0]	-5	dCas9-VP64	positive selection	2558315
109477427	109477450	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGAAAGAAAACTGGCCCCTAGG	UBE3B	ENSG00000151148	0.1475217650272076	[30,44]	[15,10]	1	dCas9-VP64	positive selection	2558316
109483598	109483621	12	-	27260157	DLD1	viability	CCTTTCTTCTCGTGCCTGACGGG	UBE3B	ENSG00000151148	0.424775720864497	[]	[]	7	hSpCas9	negative selection	2576038
109483571	109483594	12	-	27260157	DLD1	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.0564997979000011	[]	[]	3	hSpCas9	negative selection	2576110
109490548	109490571	12	+	27260157	DLD1	viability	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	-1.06544658182397	[]	[]	-7	hSpCas9	negative selection	2576502
109483616	109483639	12	+	27260157	DLD1	viability	AAAGGCTTGTGCAGAAGGAACGG	UBE3B	ENSG00000151148	0.745142079499712	[]	[]	8	hSpCas9	negative selection	2578444
109483691	109483714	12	+	27260157	DLD1	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.625137911032003	[]	[]	8	hSpCas9	negative selection	2578722
109489933	109489956	12	-	27260157	DLD1	viability	GCACAAATGTGGTTCATCGCTGG	UBE3B	ENSG00000151148	-1.49514833274038	[]	[]	-8	hSpCas9	negative selection	2579155
109488603	109488626	12	-	27260157	DLD1	viability	GACAAGCATCGTGAGGTACAGGG	UBE3B	ENSG00000151148	0.559071568415034	[]	[]	8	hSpCas9	negative selection	2583634
109483622	109483645	12	+	27260157	DLD1	viability	TTGTGCAGAAGGAACGGGAGCGG	UBE3B	ENSG00000151148	-0.934563516168558	[]	[]	-6	hSpCas9	negative selection	2587412
109488627	109488650	12	+	27260157	DLD1	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.905896202014257	[]	[]	9	hSpCas9	negative selection	2587435
109488627	109488650	12	-	27260157	DLD1	viability	CCACGTTGAAGTGTCTGTGAAGG	UBE3B	ENSG00000151148	0.553916988468569	[]	[]	8	hSpCas9	negative selection	2605213
109490538	109490561	12	+	27260157	DLD1	viability	AACCCTGTGAGGTGGTCCGTTGG	UBE3B	ENSG00000151148	-0.247270905226663	[]	[]	-2	hSpCas9	negative selection	2618479
109483641	109483664	12	+	27260157	DLD1	viability	GCGGGCAGCTGTTGTGATCCAGG	UBE3B	ENSG00000151148	0.572933614202046	[]	[]	8	hSpCas9	negative selection	2620599
109483611	109483634	12	+	27260157	DLD1	viability	AGAAGAAAGGCTTGTGCAGAAGG	UBE3B	ENSG00000151148	1.11422408864192	[]	[]	9	hSpCas9	negative selection	2620981
109483652	109483675	12	+	27260157	DLD1	viability	TTGTGATCCAGGCCCATGTCCGG	UBE3B	ENSG00000151148	0.254484287522793	[]	[]	4	hSpCas9	negative selection	2621176
109483598	109483621	12	+	27260157	DLD1	viability	CCCGTCAGGCACGAGAAGAAAGG	UBE3B	ENSG00000151148	0.784557466391862	[]	[]	8	hSpCas9	negative selection	2623758
109483584	109483607	12	+	27260157	DLD1	viability	GTTCATCGATAGAGCCCGTCAGG	UBE3B	ENSG00000151148	-0.57815268089289	[]	[]	-5	hSpCas9	negative selection	2644885
109490575	109490598	12	+	27260157	DLD1	viability	ACTGGCAGTTGTCTCGCTAGAGG	UBE3B	ENSG00000151148	-0.523961058506743	[]	[]	-4	hSpCas9	negative selection	2646757
109491044	109491067	12	+	27260157	DLD1	viability	GATATTGTTAACCCGTGGCCTGG	UBE3B	ENSG00000151148	-0.129933588601078	[]	[]	-1	hSpCas9	negative selection	2648611
109483598	109483621	12	-	27260157	HT1080	viability	CCTTTCTTCTCGTGCCTGACGGG	UBE3B	ENSG00000151148	0.283893843242168	[]	[]	2	hSpCas9	negative selection	2652168
109483571	109483594	12	-	27260157	HT1080	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.0276053313160373	[]	[]	0	hSpCas9	negative selection	2652240
109490548	109490571	12	+	27260157	HT1080	viability	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	0.100611777375909	[]	[]	1	hSpCas9	negative selection	2652632
109483616	109483639	12	+	27260157	HT1080	viability	AAAGGCTTGTGCAGAAGGAACGG	UBE3B	ENSG00000151148	0.95020087614754	[]	[]	7	hSpCas9	negative selection	2654574
109483691	109483714	12	+	27260157	HT1080	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.066770051301374	[]	[]	0	hSpCas9	negative selection	2654852
109489933	109489956	12	-	27260157	HT1080	viability	GCACAAATGTGGTTCATCGCTGG	UBE3B	ENSG00000151148	-1.75600080973508	[]	[]	-9	hSpCas9	negative selection	2655285
109488603	109488626	12	-	27260157	HT1080	viability	GACAAGCATCGTGAGGTACAGGG	UBE3B	ENSG00000151148	0.443829220730445	[]	[]	4	hSpCas9	negative selection	2659764
109483622	109483645	12	+	27260157	HT1080	viability	TTGTGCAGAAGGAACGGGAGCGG	UBE3B	ENSG00000151148	-1.19830150618989	[]	[]	-8	hSpCas9	negative selection	2663542
109488627	109488650	12	+	27260157	HT1080	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.340827568059624	[]	[]	3	hSpCas9	negative selection	2663565
109488627	109488650	12	-	27260157	HT1080	viability	CCACGTTGAAGTGTCTGTGAAGG	UBE3B	ENSG00000151148	0.0926223514518026	[]	[]	1	hSpCas9	negative selection	2681343
109490538	109490561	12	+	27260157	HT1080	viability	AACCCTGTGAGGTGGTCCGTTGG	UBE3B	ENSG00000151148	-1.60702891653496	[]	[]	-9	hSpCas9	negative selection	2694609
109483641	109483664	12	+	27260157	HT1080	viability	GCGGGCAGCTGTTGTGATCCAGG	UBE3B	ENSG00000151148	0.870792626761287	[]	[]	7	hSpCas9	negative selection	2696729
109483611	109483634	12	+	27260157	HT1080	viability	AGAAGAAAGGCTTGTGCAGAAGG	UBE3B	ENSG00000151148	1.58173573107757	[]	[]	9	hSpCas9	negative selection	2697111
109483652	109483675	12	+	27260157	HT1080	viability	TTGTGATCCAGGCCCATGTCCGG	UBE3B	ENSG00000151148	0.602674082171277	[]	[]	5	hSpCas9	negative selection	2697306
109483598	109483621	12	+	27260157	HT1080	viability	CCCGTCAGGCACGAGAAGAAAGG	UBE3B	ENSG00000151148	0.537978198233043	[]	[]	5	hSpCas9	negative selection	2699888
109483584	109483607	12	+	27260157	HT1080	viability	GTTCATCGATAGAGCCCGTCAGG	UBE3B	ENSG00000151148	-0.691787392986639	[]	[]	-8	hSpCas9	negative selection	2721015
109490575	109490598	12	+	27260157	HT1080	viability	ACTGGCAGTTGTCTCGCTAGAGG	UBE3B	ENSG00000151148	-0.43450560561662	[]	[]	-7	hSpCas9	negative selection	2722887
109491044	109491067	12	+	27260157	HT1080	viability	GATATTGTTAACCCGTGGCCTGG	UBE3B	ENSG00000151148	-0.238443056804663	[]	[]	0	hSpCas9	negative selection	2724741
109483598	109483621	12	-	27260157	MKN45	viability	CCTTTCTTCTCGTGCCTGACGGG	UBE3B	ENSG00000151148	-0.113830111813858	[]	[]	0	hSpCas9	negative selection	2728298
109483571	109483594	12	-	27260157	MKN45	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.293914028379227	[]	[]	-1	hSpCas9	negative selection	2728370
109490548	109490571	12	+	27260157	MKN45	viability	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	-1.14895336076937	[]	[]	-8	hSpCas9	negative selection	2728762
109483616	109483639	12	+	27260157	MKN45	viability	AAAGGCTTGTGCAGAAGGAACGG	UBE3B	ENSG00000151148	0.478749491722368	[]	[]	6	hSpCas9	negative selection	2730704
109483691	109483714	12	+	27260157	MKN45	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.985077418042467	[]	[]	8	hSpCas9	negative selection	2730982
109489933	109489956	12	-	27260157	MKN45	viability	GCACAAATGTGGTTCATCGCTGG	UBE3B	ENSG00000151148	-0.916553062484424	[]	[]	-7	hSpCas9	negative selection	2731415
109488603	109488626	12	-	27260157	MKN45	viability	GACAAGCATCGTGAGGTACAGGG	UBE3B	ENSG00000151148	0.452228296806444	[]	[]	6	hSpCas9	negative selection	2735894
109483622	109483645	12	+	27260157	MKN45	viability	TTGTGCAGAAGGAACGGGAGCGG	UBE3B	ENSG00000151148	-1.09655193092863	[]	[]	-8	hSpCas9	negative selection	2739672
109488627	109488650	12	+	27260157	MKN45	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.436052521078227	[]	[]	6	hSpCas9	negative selection	2739695
109488627	109488650	12	-	27260157	MKN45	viability	CCACGTTGAAGTGTCTGTGAAGG	UBE3B	ENSG00000151148	1.14987132012981	[]	[]	8	hSpCas9	negative selection	2757473
109490538	109490561	12	+	27260157	MKN45	viability	AACCCTGTGAGGTGGTCCGTTGG	UBE3B	ENSG00000151148	-0.743327576580579	[]	[]	-7	hSpCas9	negative selection	2770739
109483641	109483664	12	+	27260157	MKN45	viability	GCGGGCAGCTGTTGTGATCCAGG	UBE3B	ENSG00000151148	0.932183964079752	[]	[]	8	hSpCas9	negative selection	2772859
109483611	109483634	12	+	27260157	MKN45	viability	AGAAGAAAGGCTTGTGCAGAAGG	UBE3B	ENSG00000151148	1.54922247541574	[]	[]	9	hSpCas9	negative selection	2773241
109483652	109483675	12	+	27260157	MKN45	viability	TTGTGATCCAGGCCCATGTCCGG	UBE3B	ENSG00000151148	-0.422680075867523	[]	[]	-6	hSpCas9	negative selection	2773436
109483598	109483621	12	+	27260157	MKN45	viability	CCCGTCAGGCACGAGAAGAAAGG	UBE3B	ENSG00000151148	0.847248491879329	[]	[]	8	hSpCas9	negative selection	2776018
109483584	109483607	12	+	27260157	MKN45	viability	GTTCATCGATAGAGCCCGTCAGG	UBE3B	ENSG00000151148	0.648410453810485	[]	[]	7	hSpCas9	negative selection	2797145
109490575	109490598	12	+	27260157	MKN45	viability	ACTGGCAGTTGTCTCGCTAGAGG	UBE3B	ENSG00000151148	0.491673712112144	[]	[]	6	hSpCas9	negative selection	2799017
109491044	109491067	12	+	27260157	MKN45	viability	GATATTGTTAACCCGTGGCCTGG	UBE3B	ENSG00000151148	-0.528335196994377	[]	[]	-6	hSpCas9	negative selection	2800871
109483598	109483621	12	-	27260157	RKO	viability	CCTTTCTTCTCGTGCCTGACGGG	UBE3B	ENSG00000151148	0.224152603279618	[]	[]	1	hSpCas9	negative selection	2804428
109483571	109483594	12	-	27260157	RKO	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.208097438422823	[]	[]	1	hSpCas9	negative selection	2804500
109490548	109490571	12	+	27260157	RKO	viability	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	0.25512413365974	[]	[]	1	hSpCas9	negative selection	2804892
109483616	109483639	12	+	27260157	RKO	viability	AAAGGCTTGTGCAGAAGGAACGG	UBE3B	ENSG00000151148	0.523847970090111	[]	[]	2	hSpCas9	negative selection	2806834
109483691	109483714	12	+	27260157	RKO	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.125076267609093	[]	[]	0	hSpCas9	negative selection	2807112
109489933	109489956	12	-	27260157	RKO	viability	GCACAAATGTGGTTCATCGCTGG	UBE3B	ENSG00000151148	0.0215842324337246	[]	[]	0	hSpCas9	negative selection	2807545
109488603	109488626	12	-	27260157	RKO	viability	GACAAGCATCGTGAGGTACAGGG	UBE3B	ENSG00000151148	0.647634987080698	[]	[]	3	hSpCas9	negative selection	2812024
109483622	109483645	12	+	27260157	RKO	viability	TTGTGCAGAAGGAACGGGAGCGG	UBE3B	ENSG00000151148	-0.619271829393489	[]	[]	-7	hSpCas9	negative selection	2815802
109488627	109488650	12	+	27260157	RKO	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.683107701535654	[]	[]	7	hSpCas9	negative selection	2815825
109488627	109488650	12	-	27260157	RKO	viability	CCACGTTGAAGTGTCTGTGAAGG	UBE3B	ENSG00000151148	0.63088364249747	[]	[]	3	hSpCas9	negative selection	2833603
109490538	109490561	12	+	27260157	RKO	viability	AACCCTGTGAGGTGGTCCGTTGG	UBE3B	ENSG00000151148	-0.226442766614099	[]	[]	-1	hSpCas9	negative selection	2846869
109483641	109483664	12	+	27260157	RKO	viability	GCGGGCAGCTGTTGTGATCCAGG	UBE3B	ENSG00000151148	0.322011891720288	[]	[]	1	hSpCas9	negative selection	2848989
109483611	109483634	12	+	27260157	RKO	viability	AGAAGAAAGGCTTGTGCAGAAGG	UBE3B	ENSG00000151148	1.09218119889517	[]	[]	9	hSpCas9	negative selection	2849371
109483652	109483675	12	+	27260157	RKO	viability	TTGTGATCCAGGCCCATGTCCGG	UBE3B	ENSG00000151148	0.796344837556046	[]	[]	8	hSpCas9	negative selection	2849566
109483598	109483621	12	+	27260157	RKO	viability	CCCGTCAGGCACGAGAAGAAAGG	UBE3B	ENSG00000151148	0.971655329331138	[]	[]	8	hSpCas9	negative selection	2852148
109483584	109483607	12	+	27260157	RKO	viability	GTTCATCGATAGAGCCCGTCAGG	UBE3B	ENSG00000151148	-0.281605077184248	[]	[]	-5	hSpCas9	negative selection	2873275
109490575	109490598	12	+	27260157	RKO	viability	ACTGGCAGTTGTCTCGCTAGAGG	UBE3B	ENSG00000151148	-0.00838282009420404	[]	[]	0	hSpCas9	negative selection	2875147
109491044	109491067	12	+	27260157	RKO	viability	GATATTGTTAACCCGTGGCCTGG	UBE3B	ENSG00000151148	-0.114424673210762	[]	[]	0	hSpCas9	negative selection	2877001
109483598	109483621	12	-	27260157	SF268	viability	CCTTTCTTCTCGTGCCTGACGGG	UBE3B	ENSG00000151148	0.020541014502716	[]	[]	0	hSpCas9	negative selection	2880558
109483571	109483594	12	-	27260157	SF268	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-1.11005853682155	[]	[]	-7	hSpCas9	negative selection	2880630
109490548	109490571	12	+	27260157	SF268	viability	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	-0.643799840647326	[]	[]	-5	hSpCas9	negative selection	2881022
109483616	109483639	12	+	27260157	SF268	viability	AAAGGCTTGTGCAGAAGGAACGG	UBE3B	ENSG00000151148	0.903685801853922	[]	[]	9	hSpCas9	negative selection	2882964
109483691	109483714	12	+	27260157	SF268	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.0573661846866901	[]	[]	0	hSpCas9	negative selection	2883242
109489933	109489956	12	-	27260157	SF268	viability	GCACAAATGTGGTTCATCGCTGG	UBE3B	ENSG00000151148	-1.7004383956855	[]	[]	-8	hSpCas9	negative selection	2883675
109488603	109488626	12	-	27260157	SF268	viability	GACAAGCATCGTGAGGTACAGGG	UBE3B	ENSG00000151148	0.574576316361431	[]	[]	8	hSpCas9	negative selection	2888154
109483622	109483645	12	+	27260157	SF268	viability	TTGTGCAGAAGGAACGGGAGCGG	UBE3B	ENSG00000151148	-0.648949598950154	[]	[]	-5	hSpCas9	negative selection	2891932
109488627	109488650	12	+	27260157	SF268	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.557738264629208	[]	[]	8	hSpCas9	negative selection	2891955
109488627	109488650	12	-	27260157	SF268	viability	CCACGTTGAAGTGTCTGTGAAGG	UBE3B	ENSG00000151148	0.747838169505084	[]	[]	8	hSpCas9	negative selection	2909733
109490538	109490561	12	+	27260157	SF268	viability	AACCCTGTGAGGTGGTCCGTTGG	UBE3B	ENSG00000151148	-0.513864191006379	[]	[]	-4	hSpCas9	negative selection	2922999
109483641	109483664	12	+	27260157	SF268	viability	GCGGGCAGCTGTTGTGATCCAGG	UBE3B	ENSG00000151148	1.632525526382	[]	[]	9	hSpCas9	negative selection	2925119
109483611	109483634	12	+	27260157	SF268	viability	AGAAGAAAGGCTTGTGCAGAAGG	UBE3B	ENSG00000151148	0.647981368486979	[]	[]	8	hSpCas9	negative selection	2925501
109483652	109483675	12	+	27260157	SF268	viability	TTGTGATCCAGGCCCATGTCCGG	UBE3B	ENSG00000151148	0.0220667288484598	[]	[]	0	hSpCas9	negative selection	2925696
109483598	109483621	12	+	27260157	SF268	viability	CCCGTCAGGCACGAGAAGAAAGG	UBE3B	ENSG00000151148	0.946968029466242	[]	[]	9	hSpCas9	negative selection	2928278
109483584	109483607	12	+	27260157	SF268	viability	GTTCATCGATAGAGCCCGTCAGG	UBE3B	ENSG00000151148	0.338094131556613	[]	[]	4	hSpCas9	negative selection	2949405
109490575	109490598	12	+	27260157	SF268	viability	ACTGGCAGTTGTCTCGCTAGAGG	UBE3B	ENSG00000151148	0.913806363124681	[]	[]	9	hSpCas9	negative selection	2951277
109491044	109491067	12	+	27260157	SF268	viability	GATATTGTTAACCCGTGGCCTGG	UBE3B	ENSG00000151148	-0.239208097599784	[]	[]	-2	hSpCas9	negative selection	2953131
109486484	109486507	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.8118324805828866	[3,3]	[2,0]	-8	hSpCas9	positive selection	3030626
109483952	109483975	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.13543307699882884	[4,4]	[4,2]	-2	hSpCas9	positive selection	3030627
109483559	109483582	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGCTCTCGAGGTCTGAGACAGGG	UBE3B	ENSG00000151148	-0.1426461638677596	[4,4]	[4,2]	-2	hSpCas9	positive selection	3030628
109483563	109483586	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCTCAGACCTCGAGAGCATGG	UBE3B	ENSG00000151148	0.534793057905285	[4,3]	[4,5]	9	hSpCas9	positive selection	3030629
109486484	109486507	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.28050102723113507	[3,3]	[3,0]	-4	hSpCas9	positive selection	3098484
109483952	109483975	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.0561092327686466	[4,4]	[4,2]	-1	hSpCas9	positive selection	3098485
109483559	109483582	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGCTCTCGAGGTCTGAGACAGGG	UBE3B	ENSG00000151148	0.6842906757538552	[4,4]	[4,5]	9	hSpCas9	positive selection	3098486
109483563	109483586	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCTCAGACCTCGAGAGCATGG	UBE3B	ENSG00000151148	0.4481727765029584	[4,4]	[3,4]	7	hSpCas9	positive selection	3098487
109483902	109483925		-	24336571	A375	resistance to PLX after 7 days	ACAAAGTGCACTTCTTTTAGTGG	UBE3B	ENSG00000151148	-0.029781339542977348	[22,22]	[23,20]	-1	hSpCas9	positive selection	3153997
109483571	109483594		-	24336571	A375	resistance to PLX after 7 days	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.21026229158143206	[44,44]	[37,38]	-6	hSpCas9	positive selection	3153998
109483691	109483714		+	24336571	A375	resistance to PLX after 7 days	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.12541875820258208	[17,17]	[20,17]	4	hSpCas9	positive selection	3153999
109483954	109483977		-	24336571	A375	resistance to PLX after 7 days	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	-0.17768895886114333	[24,19]	[17,20]	-5	hSpCas9	positive selection	3154000
109483902	109483925		-	24336571	A375	resistance to PLX after 14 days	ACAAAGTGCACTTCTTTTAGTGG	UBE3B	ENSG00000151148	-1.2337725922492413	[24,25]	[4,3]	-9	hSpCas9	positive selection	3211790
109483571	109483594		-	24336571	A375	resistance to PLX after 14 days	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.11558879002014999	[51,26]	[17,21]	1	hSpCas9	positive selection	3211791
109483691	109483714		+	24336571	A375	resistance to PLX after 14 days	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.5122042733804916	[10,14]	[7,8]	5	hSpCas9	positive selection	3211792
109483954	109483977		-	24336571	A375	resistance to PLX after 14 days	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	-0.1351955771833308	[19,18]	[7,7]	-1	hSpCas9	positive selection	3211793
109483902	109483925		-	24336571	A375	viability after 7 days	ACAAAGTGCACTTCTTTTAGTGG	UBE3B	ENSG00000151148	0.7090096436623807	[14]	[22,22]	9	hSpCas9	negative selection	3269583
109483571	109483594		-	24336571	A375	viability after 7 days	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.4704477353565302	[33]	[44,44]	7	hSpCas9	negative selection	3269584
109483691	109483714		+	24336571	A375	viability after 7 days	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.0149225875181484	[18]	[17,17]	0	hSpCas9	negative selection	3269585
109483954	109483977		-	24336571	A375	viability after 7 days	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	-0.7103244735202636	[38]	[24,19]	-8	hSpCas9	negative selection	3269586
109483902	109483925		-	24336571	A375	viability after 14 days	ACAAAGTGCACTTCTTTTAGTGG	UBE3B	ENSG00000151148	0.8513449936596618	[14]	[24,25]	9	hSpCas9	negative selection	3327376
109483571	109483594		-	24336571	A375	viability after 14 days	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.2985892363930114	[33]	[51,26]	4	hSpCas9	negative selection	3327377
109483691	109483714		+	24336571	A375	viability after 14 days	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.46529076557345916	[18]	[10,14]	-5	hSpCas9	negative selection	3327378
109483954	109483977		-	24336571	A375	viability after 14 days	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	-0.9023329134883505	[38]	[19,18]	-8	hSpCas9	negative selection	3327379
109483954	109483977	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	1.0874012100035229	[71,71]	[0,0]	5	hSpCas9	positive selection	3400064
109486038	109486061	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-1.3756689856971227	[396,396]	[0,0]	-8	hSpCas9	positive selection	3400065
109486029	109486052	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.4841407749553118	[213,213]	[0,0]	-3	hSpCas9	positive selection	3400066
109486484	109486507	12	-	26780180	HT29	viability (Avana library 4 designs)	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.445727605342611	[]	[]	1	hSpCas9	negative selection	3469555
109483951	109483974	12	+	26780180	HT29	viability (Avana library 4 designs)	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.685404802682047	[]	[]	2	hSpCas9	negative selection	3469556
109483559	109483582	12	-	26780180	HT29	viability (Avana library 4 designs)	TGCTCTCGAGGTCTGAGACAGGG	UBE3B	ENSG00000151148	0.626938997645669	[]	[]	2	hSpCas9	negative selection	3469557
109483562	109483585	12	+	26780180	HT29	viability (Avana library 4 designs)	TGTCTCAGACCTCGAGAGCATGG	UBE3B	ENSG00000151148	-0.194459561633629	[]	[]	-3	hSpCas9	negative selection	3469558
109483559	109483582	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGCTCTCGAGGTCTGAGACAGGG	UBE3B	ENSG00000151148	1.9577777001616	[]	[]	3	hSpCas9	negative selection	3574849
109486484	109486507	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-1.12226234678997	[]	[]	-1	hSpCas9	negative selection	3574850
109483951	109483974	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-9.77623091264002	[]	[]	-7	hSpCas9	negative selection	3574851
109483562	109483585	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCTCAGACCTCGAGAGCATGG	UBE3B	ENSG00000151148	3.37072374103922	[]	[]	5	hSpCas9	negative selection	3574852
109483599	109483622	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTTTCTTCTCGTGCCTGACGG	UBE3B	ENSG00000151148	1.25615326322775	[]	[]	1	hSpCas9	negative selection	3574853
109483584	109483607	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCATCGATAGAGCCCGTCAGG	UBE3B	ENSG00000151148	3.76175761260157	[]	[]	6	hSpCas9	negative selection	3574854
109483559	109483582	12	-	26780180	A375	viability (Avana lentiGuide)	TGCTCTCGAGGTCTGAGACAGGG	UBE3B	ENSG00000151148	-1.48234261460086	[]	[]	-2	hSpCas9	negative selection	3683508
109486484	109486507	12	-	26780180	A375	viability (Avana lentiGuide)	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.719124313110767	[]	[]	-1	hSpCas9	negative selection	3683509
109483951	109483974	12	+	26780180	A375	viability (Avana lentiGuide)	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-6.67492349205083	[]	[]	-9	hSpCas9	negative selection	3683510
109483562	109483585	12	+	26780180	A375	viability (Avana lentiGuide)	TGTCTCAGACCTCGAGAGCATGG	UBE3B	ENSG00000151148	-1.16371830980114	[]	[]	-2	hSpCas9	negative selection	3683511
109483599	109483622	12	-	26780180	A375	viability (Avana lentiGuide)	GCCTTTCTTCTCGTGCCTGACGG	UBE3B	ENSG00000151148	-5.18343643611439	[]	[]	-8	hSpCas9	negative selection	3683512
109483584	109483607	12	+	26780180	A375	viability (Avana lentiGuide)	GTTCATCGATAGAGCCCGTCAGG	UBE3B	ENSG00000151148	3.0274436335585	[]	[]	3	hSpCas9	negative selection	3683513
109483559	109483582	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCTCTCGAGGTCTGAGACAGGG	UBE3B	ENSG00000151148	0.06219278376156567	[6]	[6,5]	1	hSpCas9	positive selection	3792115
109486484	109486507	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.08627281887380495	[5]	[5,5]	2	hSpCas9	positive selection	3792116
109483951	109483974	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.7337971312513862	[6]	[4,2]	-8	hSpCas9	positive selection	3792117
109483562	109483585	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCTCAGACCTCGAGAGCATGG	UBE3B	ENSG00000151148	0.2246433902665442	[5]	[6,6]	6	hSpCas9	positive selection	3792118
109483599	109483622	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTTTCTTCTCGTGCCTGACGG	UBE3B	ENSG00000151148	0.1455623289807939	[6]	[7,6]	4	hSpCas9	positive selection	3792119
109483584	109483607	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCATCGATAGAGCCCGTCAGG	UBE3B	ENSG00000151148	0.2790419587499592	[4]	[5,5]	7	hSpCas9	positive selection	3792120
109483559	109483582	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCTCTCGAGGTCTGAGACAGGG	UBE3B	ENSG00000151148	-0.08412190157840177	[6]	[5,4]	-1	hSpCas9	positive selection	3900722
109486484	109486507	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.1597564676252209	[5]	[4,2]	-2	hSpCas9	positive selection	3900723
109483951	109483974	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.20252651538049074	[5]	[5,6]	5	hSpCas9	positive selection	3900724
109483562	109483585	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCTCAGACCTCGAGAGCATGG	UBE3B	ENSG00000151148	0.03724313295762924	[6]	[5,5]	0	hSpCas9	positive selection	3900725
109483599	109483622	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTTTCTTCTCGTGCCTGACGG	UBE3B	ENSG00000151148	0.3301292002135253	[6]	[7,7]	8	hSpCas9	positive selection	3900726
109483584	109483607	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCATCGATAGAGCCCGTCAGG	UBE3B	ENSG00000151148	-0.05805536435776644	[5]	[4,3]	-1	hSpCas9	positive selection	3900727
109483571	109483594	12	-	26780180	A375	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.526522386033896	[]	[]	1	hSpCas9	negative selection	4009816
109483691	109483714	12	+	26780180	A375	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	1.22301737265363	[]	[]	6	hSpCas9	negative selection	4009817
109483951	109483974	12	+	26780180	A375	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	1.55644506809067	[]	[]	8	hSpCas9	negative selection	4009818
109483954	109483977	12	-	26780180	A375	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.814278295827751	[]	[]	3	hSpCas9	negative selection	4009819
109486029	109486052	12	+	26780180	A375	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	1.51151061149111	[]	[]	8	hSpCas9	negative selection	4009820
109486038	109486061	12	-	26780180	A375	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.938242656998975	[]	[]	4	hSpCas9	negative selection	4009821
109483571	109483594	12	-	26780180	HT29	viability (GeCKOv2 library)	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.389765612198943	[]	[]	1	hSpCas9	negative selection	4117782
109483691	109483714	12	+	26780180	HT29	viability (GeCKOv2 library)	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	1.61107780560276	[]	[]	8	hSpCas9	negative selection	4117783
109483951	109483974	12	+	26780180	HT29	viability (GeCKOv2 library)	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	1.57070085151316	[]	[]	8	hSpCas9	negative selection	4117784
109483954	109483977	12	-	26780180	HT29	viability (GeCKOv2 library)	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.84535464958257	[]	[]	3	hSpCas9	negative selection	4117785
109486029	109486052	12	+	26780180	HT29	viability (GeCKOv2 library)	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	0.442421242067562	[]	[]	1	hSpCas9	negative selection	4117786
109486038	109486061	12	-	26780180	HT29	viability (GeCKOv2 library)	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.956077890904069	[]	[]	4	hSpCas9	negative selection	4117787
109483902	109483925	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAAAGTGCACTTCTTTTAGTGG	UBE3B	ENSG00000151148	0.016306847486221854	[4]	[4,2]	0	hSpCas9	positive selection	4180670
109483571	109483594	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.2480968669925384	[5]	[4,4]	6	hSpCas9	positive selection	4180671
109483691	109483714	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.020412772521585548	[4]	[2,2]	0	hSpCas9	positive selection	4180672
109483954	109483977	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.07906626542749129	[4]	[3,2]	2	hSpCas9	positive selection	4180673
109483902	109483925	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAAAGTGCACTTCTTTTAGTGG	UBE3B	ENSG00000151148	0.7662809124008854	[4]	[4,1,4,3]	5	hSpCas9	positive selection	4244692
109483571	109483594	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.20670875257136206	[5]	[2,4,1,0]	-3	hSpCas9	positive selection	4244693
109483691	109483714	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.1589234022011331	[3]	[0,2,1,0]	1	hSpCas9	positive selection	4244694
109483954	109483977	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	1.0250422191112496	[5]	[4,5,2,5]	7	hSpCas9	positive selection	4244695
109483571	109483594	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.14489892361106294	[0]	[1,0]	3	hSpCas9	positive selection	4306299
109483691	109483714	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.2933309874190427	[3]	[1,1]	-6	hSpCas9	positive selection	4306300
109483951	109483974	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.31856442137673613	[2]	[3,2]	6	hSpCas9	positive selection	4306301
109483954	109483977	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	-0.06703424879964143	[2]	[2,0]	-1	hSpCas9	positive selection	4370548
109486038	109486061	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.12946806915678122	[4]	[4,2]	2	hSpCas9	positive selection	4370549
109486029	109486052	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.2198332256063866	[3]	[2,1]	-4	hSpCas9	positive selection	4370550
109483665	109483687	12	-	27760321	OCIAML3	viability	ACAGAGAAAACTCCGGACATGG	UBE3B	ENSG00000151148	0.7271615184973116	[340,200]	[232,489]	8	hSpCas9	negative selection	4451863
109483698	109483720	12	+	27760321	OCIAML3	viability	GCAGAGAGATATCAGGTAAGGG	UBE3B	ENSG00000151148	0.9729298919543338	[123,127]	[169,225]	9	hSpCas9	negative selection	4451864
109483895	109483917	12	-	27760321	OCIAML3	viability	CACTTCTTTTAGTGGACTCAGG	UBE3B	ENSG00000151148	-0.1304615405283947	[567,486]	[350,407]	-1	hSpCas9	negative selection	4451865
109486509	109486531	12	-	27760321	OCIAML3	viability	GATCTGTTGAATCCAAAGGAGG	UBE3B	ENSG00000151148	-0.3551944267786624	[302,224]	[149,172]	-4	hSpCas9	negative selection	4451866
109488604	109488626	12	-	27760321	OCIAML3	viability	GACAAGCATCGTGAGGTACAGG	UBE3B	ENSG00000151148	-0.11593291869805264	[587,470]	[306,474]	-1	hSpCas9	negative selection	4451867
109483665	109483687	12	-	27760321	OCIAML2	viability	ACAGAGAAAACTCCGGACATGG	UBE3B	ENSG00000151148	0.5259936632743412	[340,200]	[265,367]	7	hSpCas9	negative selection	4535326
109483698	109483720	12	+	27760321	OCIAML2	viability	GCAGAGAGATATCAGGTAAGGG	UBE3B	ENSG00000151148	0.6211232341181663	[123,127]	[147,169]	8	hSpCas9	negative selection	4535327
109483895	109483917	12	-	27760321	OCIAML2	viability	CACTTCTTTTAGTGGACTCAGG	UBE3B	ENSG00000151148	0.5782254981019698	[567,486]	[607,670]	7	hSpCas9	negative selection	4535328
109486509	109486531	12	-	27760321	OCIAML2	viability	GATCTGTTGAATCCAAAGGAGG	UBE3B	ENSG00000151148	0.3544338240037284	[302,224]	[220,335]	5	hSpCas9	negative selection	4535329
109488604	109488626	12	-	27760321	OCIAML2	viability	GACAAGCATCGTGAGGTACAGG	UBE3B	ENSG00000151148	0.3099848158503205	[587,470]	[514,544]	4	hSpCas9	negative selection	4535330
109483665	109483687	12	-	27760321	MV411	viability	ACAGAGAAAACTCCGGACATGG	UBE3B	ENSG00000151148	-0.30038275213209376	[340,200]	[162,111]	-2	hSpCas9	negative selection	4618789
109483698	109483720	12	+	27760321	MV411	viability	GCAGAGAGATATCAGGTAAGGG	UBE3B	ENSG00000151148	0.3129193396459371	[123,127]	[56,173]	2	hSpCas9	negative selection	4618790
109483895	109483917	12	-	27760321	MV411	viability	CACTTCTTTTAGTGGACTCAGG	UBE3B	ENSG00000151148	0.28004650117197927	[567,486]	[175,789]	2	hSpCas9	negative selection	4618791
109486509	109486531	12	-	27760321	MV411	viability	GATCTGTTGAATCCAAAGGAGG	UBE3B	ENSG00000151148	-1.5210689690986605	[302,224]	[16,124]	-7	hSpCas9	negative selection	4618792
109488604	109488626	12	-	27760321	MV411	viability	GACAAGCATCGTGAGGTACAGG	UBE3B	ENSG00000151148	-0.8250935150364371	[587,470]	[58,401]	-5	hSpCas9	negative selection	4618793
109483665	109483687	12	-	27760321	HL60	viability	ACAGAGAAAACTCCGGACATGG	UBE3B	ENSG00000151148	-0.2422678219892188	[340,200]	[143,225]	-3	hSpCas9	negative selection	4702252
109483698	109483720	12	+	27760321	HL60	viability	GCAGAGAGATATCAGGTAAGGG	UBE3B	ENSG00000151148	0.9449449045983055	[123,127]	[117,284]	8	hSpCas9	negative selection	4702253
109483895	109483917	12	-	27760321	HL60	viability	CACTTCTTTTAGTGGACTCAGG	UBE3B	ENSG00000151148	1.1519365866003985	[567,486]	[1339,545]	9	hSpCas9	negative selection	4702254
109486509	109486531	12	-	27760321	HL60	viability	GATCTGTTGAATCCAAAGGAGG	UBE3B	ENSG00000151148	0.726758870450579	[302,224]	[344,362]	8	hSpCas9	negative selection	4702255
109488604	109488626	12	-	27760321	HL60	viability	GACAAGCATCGTGAGGTACAGG	UBE3B	ENSG00000151148	1.3764512920538707	[587,470]	[1165,1063]	9	hSpCas9	negative selection	4702256
109483665	109483687	12	-	27760321	HT1080	viability	ACAGAGAAAACTCCGGACATGG	UBE3B	ENSG00000151148	0.1830962982037767	[200,156]	[37,127]	0	hSpCas9	negative selection	4785715
109483698	109483720	12	+	27760321	HT1080	viability	GCAGAGAGATATCAGGTAAGGG	UBE3B	ENSG00000151148	1.2135758074635792	[127,99]	[48,166]	6	hSpCas9	negative selection	4785716
109483895	109483917	12	-	27760321	HT1080	viability	CACTTCTTTTAGTGGACTCAGG	UBE3B	ENSG00000151148	1.3422310119703262	[486,379]	[402,475]	7	hSpCas9	negative selection	4785717
109486509	109486531	12	-	27760321	HT1080	viability	GATCTGTTGAATCCAAAGGAGG	UBE3B	ENSG00000151148	0.5169227734899526	[224,175]	[183,37]	2	hSpCas9	negative selection	4785718
109488604	109488626	12	-	27760321	HT1080	viability	GACAAGCATCGTGAGGTACAGG	UBE3B	ENSG00000151148	0.7790832278377661	[470,367]	[408,152]	4	hSpCas9	negative selection	4785719
109483665	109483687	12	-	27760321	HT29	viability after 7 days	ACAGAGAAAACTCCGGACATGG	UBE3B	ENSG00000151148	0.7362965833954782	[200,156]	[352,397,393]	9	hSpCas9	negative selection	4869178
109483698	109483720	12	+	27760321	HT29	viability after 7 days	GCAGAGAGATATCAGGTAAGGG	UBE3B	ENSG00000151148	0.3648111788024977	[127,99]	[290,209,82]	5	hSpCas9	negative selection	4869179
109483895	109483917	12	-	27760321	HT29	viability after 7 days	CACTTCTTTTAGTGGACTCAGG	UBE3B	ENSG00000151148	-0.16505412842077724	[486,379]	[562,440,495]	-2	hSpCas9	negative selection	4869180
109486509	109486531	12	-	27760321	HT29	viability after 7 days	GATCTGTTGAATCCAAAGGAGG	UBE3B	ENSG00000151148	-0.3450550620810803	[224,175]	[146,356,99]	-5	hSpCas9	negative selection	4869181
109488604	109488626	12	-	27760321	HT29	viability after 7 days	GACAAGCATCGTGAGGTACAGG	UBE3B	ENSG00000151148	0.2308944281031207	[470,367]	[723,741,450]	3	hSpCas9	negative selection	4869182
109483665	109483687	12	-	27760321	HT29	viability after 25 days	ACAGAGAAAACTCCGGACATGG	UBE3B	ENSG00000151148	0.7271443342104345	[200,156]	[290,357,372]	8	hSpCas9	negative selection	4952641
109483698	109483720	12	+	27760321	HT29	viability after 25 days	GCAGAGAGATATCAGGTAAGGG	UBE3B	ENSG00000151148	0.8360284387863128	[127,99]	[167,235,304]	8	hSpCas9	negative selection	4952642
109483895	109483917	12	-	27760321	HT29	viability after 25 days	CACTTCTTTTAGTGGACTCAGG	UBE3B	ENSG00000151148	0.40812456512327566	[486,379]	[622,712,634]	4	hSpCas9	negative selection	4952643
109486509	109486531	12	-	27760321	HT29	viability after 25 days	GATCTGTTGAATCCAAAGGAGG	UBE3B	ENSG00000151148	0.4883197315221831	[224,175]	[238,340,396]	5	hSpCas9	negative selection	4952644
109488604	109488626	12	-	27760321	HT29	viability after 25 days	GACAAGCATCGTGAGGTACAGG	UBE3B	ENSG00000151148	0.6822255175145558	[470,367]	[633,733,967]	7	hSpCas9	negative selection	4952645
109483665	109483687	12	-	27760321	HT29	viability after 22 days	ACAGAGAAAACTCCGGACATGG	UBE3B	ENSG00000151148	0.6496044004341385	[200,156]	[254,373,346]	7	hSpCas9	negative selection	5036104
109483698	109483720	12	+	27760321	HT29	viability after 22 days	GCAGAGAGATATCAGGTAAGGG	UBE3B	ENSG00000151148	0.8611413308034986	[127,99]	[203,188,326]	8	hSpCas9	negative selection	5036105
109483895	109483917	12	-	27760321	HT29	viability after 22 days	CACTTCTTTTAGTGGACTCAGG	UBE3B	ENSG00000151148	0.3531293829531399	[486,379]	[570,627,723]	4	hSpCas9	negative selection	5036106
109486509	109486531	12	-	27760321	HT29	viability after 22 days	GATCTGTTGAATCCAAAGGAGG	UBE3B	ENSG00000151148	0.2786411748272416	[224,175]	[306,350,183]	3	hSpCas9	negative selection	5036107
109488604	109488626	12	-	27760321	HT29	viability after 22 days	GACAAGCATCGTGAGGTACAGG	UBE3B	ENSG00000151148	0.6381119505645931	[470,367]	[853,722,683]	7	hSpCas9	negative selection	5036108
109483665	109483687	12	-	27760321	HT29	viability after 19 days	ACAGAGAAAACTCCGGACATGG	UBE3B	ENSG00000151148	0.8723386949614218	[200,156]	[280,477,355]	8	hSpCas9	negative selection	5119567
109483698	109483720	12	+	27760321	HT29	viability after 19 days	GCAGAGAGATATCAGGTAAGGG	UBE3B	ENSG00000151148	0.22897263422669467	[127,99]	[269,111,90]	2	hSpCas9	negative selection	5119568
109483895	109483917	12	-	27760321	HT29	viability after 19 days	CACTTCTTTTAGTGGACTCAGG	UBE3B	ENSG00000151148	0.015175643210620426	[486,379]	[563,435,508]	0	hSpCas9	negative selection	5119569
109486509	109486531	12	-	27760321	HT29	viability after 19 days	GATCTGTTGAATCCAAAGGAGG	UBE3B	ENSG00000151148	0.17285761975889824	[224,175]	[280,163,329]	1	hSpCas9	negative selection	5119570
109488604	109488626	12	-	27760321	HT29	viability after 19 days	GACAAGCATCGTGAGGTACAGG	UBE3B	ENSG00000151148	0.7894003137600335	[470,367]	[821,687,970]	7	hSpCas9	negative selection	5119571
109483665	109483687	12	-	27760321	HT29	viability after 16 days	ACAGAGAAAACTCCGGACATGG	UBE3B	ENSG00000151148	0.48430728063012585	[200,156]	[309,175,359]	5	hSpCas9	negative selection	5203030
109483698	109483720	12	+	27760321	HT29	viability after 16 days	GCAGAGAGATATCAGGTAAGGG	UBE3B	ENSG00000151148	1.2320549791179394	[127,99]	[268,219,408]	9	hSpCas9	negative selection	5203031
109483895	109483917	12	-	27760321	HT29	viability after 16 days	CACTTCTTTTAGTGGACTCAGG	UBE3B	ENSG00000151148	0.6695656619430431	[486,379]	[711,715,881]	7	hSpCas9	negative selection	5203032
109486509	109486531	12	-	27760321	HT29	viability after 16 days	GATCTGTTGAATCCAAAGGAGG	UBE3B	ENSG00000151148	-0.11949980236738633	[224,175]	[216,225,176]	-1	hSpCas9	negative selection	5203033
109488604	109488626	12	-	27760321	HT29	viability after 16 days	GACAAGCATCGTGAGGTACAGG	UBE3B	ENSG00000151148	0.32745829308004926	[470,367]	[660,573,538]	3	hSpCas9	negative selection	5203034
109483665	109483687	12	-	27760321	HT29	viability after 13 days	ACAGAGAAAACTCCGGACATGG	UBE3B	ENSG00000151148	0.7621322540609022	[200,156]	[430,300,325]	8	hSpCas9	negative selection	5286493
109483698	109483720	12	+	27760321	HT29	viability after 13 days	GCAGAGAGATATCAGGTAAGGG	UBE3B	ENSG00000151148	1.231392724715989	[127,99]	[322,288,318]	9	hSpCas9	negative selection	5286494
109483895	109483917	12	-	27760321	HT29	viability after 13 days	CACTTCTTTTAGTGGACTCAGG	UBE3B	ENSG00000151148	0.27488046599668525	[486,379]	[470,565,777]	3	hSpCas9	negative selection	5286495
109486509	109486531	12	-	27760321	HT29	viability after 13 days	GATCTGTTGAATCCAAAGGAGG	UBE3B	ENSG00000151148	0.09754794354581642	[224,175]	[215,251,276]	1	hSpCas9	negative selection	5286496
109488604	109488626	12	-	27760321	HT29	viability after 13 days	GACAAGCATCGTGAGGTACAGG	UBE3B	ENSG00000151148	0.9015723067349649	[470,367]	[1194,728,808]	9	hSpCas9	negative selection	5286497
109483665	109483687	12	-	27760321	HT29	viability after 10 days	ACAGAGAAAACTCCGGACATGG	UBE3B	ENSG00000151148	0.7384908468825675	[200,156]	[502,301,312]	8	hSpCas9	negative selection	5369956
109483698	109483720	12	+	27760321	HT29	viability after 10 days	GCAGAGAGATATCAGGTAAGGG	UBE3B	ENSG00000151148	1.0409413159610572	[127,99]	[241,483,160]	9	hSpCas9	negative selection	5369957
109483895	109483917	12	-	27760321	HT29	viability after 10 days	CACTTCTTTTAGTGGACTCAGG	UBE3B	ENSG00000151148	-0.2856349651583291	[486,379]	[629,420,283]	-4	hSpCas9	negative selection	5369958
109486509	109486531	12	-	27760321	HT29	viability after 10 days	GATCTGTTGAATCCAAAGGAGG	UBE3B	ENSG00000151148	0.13638694038963395	[224,175]	[360,205,256]	1	hSpCas9	negative selection	5369959
109488604	109488626	12	-	27760321	HT29	viability after 10 days	GACAAGCATCGTGAGGTACAGG	UBE3B	ENSG00000151148	0.630092933407041	[470,367]	[757,1056,627]	8	hSpCas9	negative selection	5369960
109483665	109483687	12	-	27760321	MOLM13	viability	ACAGAGAAAACTCCGGACATGG	UBE3B	ENSG00000151148	0.6327643566059061	[340,200]	[288,184]	4	hSpCas9	negative selection	5453419
109483698	109483720	12	+	27760321	MOLM13	viability	GCAGAGAGATATCAGGTAAGGG	UBE3B	ENSG00000151148	0.19154054630442485	[123,127]	[100,64]	1	hSpCas9	negative selection	5453420
109483895	109483917	12	-	27760321	MOLM13	viability	CACTTCTTTTAGTGGACTCAGG	UBE3B	ENSG00000151148	0.43541605292814134	[567,486]	[444,363]	3	hSpCas9	negative selection	5453421
109486509	109486531	12	-	27760321	MOLM13	viability	GATCTGTTGAATCCAAAGGAGG	UBE3B	ENSG00000151148	0.5441387878635034	[302,224]	[56,349]	4	hSpCas9	negative selection	5453422
109488604	109488626	12	-	27760321	MOLM13	viability	GACAAGCATCGTGAGGTACAGG	UBE3B	ENSG00000151148	0.10430229552939146	[587,470]	[180,436]	0	hSpCas9	negative selection	5453423
109477622	109477645	12	+	27661255	K562	viability	GGTTCTGAAAGCGAACACCGCGG	UBE3B	ENSG00000151148	0.0046658587011431454	[666,804]	[596,579]	0	dCas9-KRAB	negative selection	5521175
109477632	109477655	12	+	27661255	K562	viability	GCGAACACCGCGGGGCAAGATGG	UBE3B	ENSG00000151148	0.0043753400384188845	[340,509]	[304,366]	0	dCas9-KRAB	negative selection	5521176
109477646	109477669	12	+	27661255	K562	viability	GCAAGATGGCGGTAGTGCGTCGG	UBE3B	ENSG00000151148	0.23127140930608597	[923,1018]	[978,849]	7	dCas9-KRAB	negative selection	5521177
109477413	109477436	12	-	27661255	K562	viability	GCCCCTAGGCGCACAACGGACGG	UBE3B	ENSG00000151148	0.07461722868782839	[424,512]	[464,331]	2	dCas9-KRAB	negative selection	5521178
109483571	109483594	12	-	27260156	BXPC3	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.6346101997384594	[63]	[57,136,103,120]	9	hSpCas9	negative selection	5578759
109483691	109483714	12	+	27260156	BXPC3	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.2782570432724005	[496]	[333,415,480,500]	-6	hSpCas9	negative selection	5578760
109483951	109483974	12	+	27260156	BXPC3	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.20912542736095752	[340]	[348,409,383,522]	4	hSpCas9	negative selection	5578761
109483954	109483977	12	-	27260156	BXPC3	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.3705010226601678	[202]	[270,228,280,323]	7	hSpCas9	negative selection	5643008
109486038	109486061	12	-	27260156	BXPC3	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.1186362612539742	[1045]	[912,998,916,1229]	-3	hSpCas9	negative selection	5643009
109486029	109486052	12	+	27260156	BXPC3	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	0.03278576416858123	[506]	[446,454,719,564]	0	hSpCas9	negative selection	5643010
109483571	109483594	12	-	27260156	A673	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.3963326202567692	[63]	[94,125,112,66]	8	hSpCas9	negative selection	5700010
109483691	109483714	12	+	27260156	A673	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.076312095410646	[496]	[834,603,593,499]	1	hSpCas9	negative selection	5700011
109483951	109483974	12	+	27260156	A673	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.20247538252160163	[340]	[484,454,424,523]	5	hSpCas9	negative selection	5700012
109483954	109483977	12	-	27260156	A673	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.2883810882091985	[202]	[382,247,250,320]	6	hSpCas9	negative selection	5764259
109486038	109486061	12	-	27260156	A673	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.038730379804552184	[1045]	[1526,1056,1175,1164]	-1	hSpCas9	negative selection	5764260
109486029	109486052	12	+	27260156	A673	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.05099178279460974	[506]	[640,528,641,541]	-1	hSpCas9	negative selection	5764261
109483571	109483594	12	-	27260156	A375	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.49965692008454177	[63]	[73,37,206,94]	7	hSpCas9	negative selection	5821261
109483691	109483714	12	+	27260156	A375	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.30780390441290345	[496]	[507,459,527,386]	-4	hSpCas9	negative selection	5821262
109483951	109483974	12	+	27260156	A375	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.26130626403920454	[340]	[485,413,531,467]	4	hSpCas9	negative selection	5821263
109483954	109483977	12	-	27260156	A375	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.776789149480202	[202]	[398,632,319,313]	9	hSpCas9	negative selection	5885510
109486038	109486061	12	-	27260156	A375	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.10817482185051475	[1045]	[1329,1851,1172,1017]	1	hSpCas9	negative selection	5885511
109486029	109486052	12	+	27260156	A375	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.018269484417493292	[506]	[527,829,618,413]	0	hSpCas9	negative selection	5885512
109483571	109483594	12	-	27260156	COLO741	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.1476890918316549	[63]	[116,49,58]	-3	hSpCas9	negative selection	5942512
109483691	109483714	12	+	27260156	COLO741	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.07775172786343267	[496]	[613,438,740]	-2	hSpCas9	negative selection	5942513
109483951	109483974	12	+	27260156	COLO741	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.14335201018122595	[340]	[459,458,277]	-3	hSpCas9	negative selection	5942514
109483954	109483977	12	-	27260156	COLO741	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.18424908771006754	[202]	[172,232,454]	4	hSpCas9	negative selection	6006761
109486038	109486061	12	-	27260156	COLO741	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.09241603316097624	[1045]	[1411,1133,1226]	-2	hSpCas9	negative selection	6006762
109486029	109486052	12	+	27260156	COLO741	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.11255446706531551	[506]	[556,570,659]	-2	hSpCas9	negative selection	6006763
109483571	109483594	12	-	27260156	CAL120	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.01575203060308006	[63]	[103,57,82]	0	hSpCas9	negative selection	6063763
109483691	109483714	12	+	27260156	CAL120	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.021495470648944658	[496]	[551,709,557]	0	hSpCas9	negative selection	6063764
109483951	109483974	12	+	27260156	CAL120	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.38730088317237504	[340]	[332,403,238]	-5	hSpCas9	negative selection	6063765
109483954	109483977	12	-	27260156	CAL120	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	-0.021881993337466543	[202]	[258,359,130]	0	hSpCas9	negative selection	6128012
109486038	109486061	12	-	27260156	CAL120	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.24209502667725502	[1045]	[1214,979,1122]	-4	hSpCas9	negative selection	6128013
109486029	109486052	12	+	27260156	CAL120	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.10228375703351307	[506]	[558,633,565]	-1	hSpCas9	negative selection	6128014
109483571	109483594	12	-	27260156	CADOES1	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.17661465220121375	[63]	[67,93,43,62]	3	hSpCas9	negative selection	6185014
109483691	109483714	12	+	27260156	CADOES1	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.10908653294569295	[496]	[364,479,480,386]	-2	hSpCas9	negative selection	6185015
109483951	109483974	12	+	27260156	CADOES1	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.20099045810931637	[340]	[435,341,315,363]	3	hSpCas9	negative selection	6185016
109483954	109483977	12	-	27260156	CADOES1	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.27491117363021156	[202]	[228,349,157,174]	4	hSpCas9	negative selection	6249263
109486038	109486061	12	-	27260156	CADOES1	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.2069880054200134	[1045]	[742,928,797,903]	-4	hSpCas9	negative selection	6249264
109486029	109486052	12	+	27260156	CADOES1	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.130571527548786	[506]	[367,499,379,476]	-2	hSpCas9	negative selection	6249265
109483571	109483594	12	-	27260156	EWS502	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.2375207069162184	[63]	[26,55,93,56]	-4	hSpCas9	negative selection	6306265
109483691	109483714	12	+	27260156	EWS502	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.27882895292238946	[496]	[321,411,637,374]	-5	hSpCas9	negative selection	6306266
109483951	109483974	12	+	27260156	EWS502	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.19344691698365002	[340]	[405,292,497,463]	3	hSpCas9	negative selection	6306267
109483954	109483977	12	-	27260156	EWS502	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.09049860373900809	[202]	[225,250,159,279]	1	hSpCas9	negative selection	6370514
109486038	109486061	12	-	27260156	EWS502	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.037610143403620455	[1045]	[991,1188,908,1491]	0	hSpCas9	negative selection	6370515
109486029	109486052	12	+	27260156	EWS502	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	0.21104022448464932	[506]	[621,629,551,682]	3	hSpCas9	negative selection	6370516
109483571	109483594	12	-	27260156	EW8	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.15303777120625872	[63]	[48,47,50,37]	-3	hSpCas9	negative selection	6427516
109483691	109483714	12	+	27260156	EW8	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.16296905958467375	[496]	[459,263,332,395]	-3	hSpCas9	negative selection	6427517
109483951	109483974	12	+	27260156	EW8	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.17658982848897198	[340]	[418,308,260,279]	3	hSpCas9	negative selection	6427518
109483954	109483977	12	-	27260156	EW8	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.48475156133651787	[202]	[253,221,300,133]	8	hSpCas9	negative selection	6491765
109486038	109486061	12	-	27260156	EW8	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.04751521963617633	[1045]	[992,789,620,926]	-1	hSpCas9	negative selection	6491766
109486029	109486052	12	+	27260156	EW8	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.35756190095903684	[506]	[458,337,215,301]	-6	hSpCas9	negative selection	6491767
109483571	109483594	12	-	27260156	CORL105	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.014342791948951383	[63]	[106,41,91,65]	0	hSpCas9	negative selection	6548767
109483691	109483714	12	+	27260156	CORL105	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.40605289360484675	[496]	[439,413,434,466]	-6	hSpCas9	negative selection	6548768
109483951	109483974	12	+	27260156	CORL105	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.3293926175497918	[340]	[267,381,424,209]	-6	hSpCas9	negative selection	6548769
109483954	109483977	12	-	27260156	CORL105	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	-0.21150303101101087	[202]	[237,191,202,188]	-4	hSpCas9	negative selection	6613016
109486038	109486061	12	-	27260156	CORL105	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.21384116579522894	[1045]	[926,1120,1361,855]	-4	hSpCas9	negative selection	6613017
109486029	109486052	12	+	27260156	CORL105	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	0.0796899058273556	[506]	[614,595,684,621]	1	hSpCas9	negative selection	6613018
109483571	109483594	12	-	27260156	HS294T	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.7256443892424556	[63]	[77,14,25,41]	8	hSpCas9	negative selection	6670018
109483691	109483714	12	+	27260156	HS294T	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.09823364182421365	[496]	[172,232,121,189]	-1	hSpCas9	negative selection	6670019
109483951	109483974	12	+	27260156	HS294T	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.08010943993458558	[340]	[99,104,182,180]	1	hSpCas9	negative selection	6670020
109483954	109483977	12	-	27260156	HS294T	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	-0.39810699746762523	[202]	[49,36,46,114]	-5	hSpCas9	negative selection	6734267
109486038	109486061	12	-	27260156	HS294T	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.08742902624056037	[1045]	[343,374,506,515]	1	hSpCas9	negative selection	6734268
109486029	109486052	12	+	27260156	HS294T	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.07315889351265038	[506]	[152,159,188,258]	-1	hSpCas9	negative selection	6734269
109483571	109483594	12	-	27260156	HCC44	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.02714333726166318	[63]	[117,63,40,60]	0	hSpCas9	negative selection	6791269
109483691	109483714	12	+	27260156	HCC44	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.13882566513945235	[496]	[492,559,501,473]	-2	hSpCas9	negative selection	6791270
109483951	109483974	12	+	27260156	HCC44	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.12859836327844693	[340]	[385,252,503,309]	-2	hSpCas9	negative selection	6791271
109483954	109483977	12	-	27260156	HCC44	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.5920481084007473	[202]	[265,242,602,321]	8	hSpCas9	negative selection	6855518
109486038	109486061	12	-	27260156	HCC44	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.1814616685385797	[1045]	[1477,999,1435,1512]	3	hSpCas9	negative selection	6855519
109486029	109486052	12	+	27260156	HCC44	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.049268071181531745	[506]	[442,359,978,521]	-1	hSpCas9	negative selection	6855520
109483571	109483594	12	-	27260156	G402	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-1.6304399239019811	[63]	[0,7,76,10]	-9	hSpCas9	negative selection	6912520
109483691	109483714	12	+	27260156	G402	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.03407274176879438	[496]	[731,662,699,414]	0	hSpCas9	negative selection	6912521
109483951	109483974	12	+	27260156	G402	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.011749008857961096	[340]	[366,709,323,290]	0	hSpCas9	negative selection	6912522
109483954	109483977	12	-	27260156	G402	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.38951773445825966	[202]	[292,458,97,443]	5	hSpCas9	negative selection	6976769
109486038	109486061	12	-	27260156	G402	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.0328312833891764	[1045]	[1256,1492,1152,1317]	0	hSpCas9	negative selection	6976770
109486029	109486052	12	+	27260156	G402	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.1244890514661423	[506]	[762,817,276,457]	-1	hSpCas9	negative selection	6976771
109483571	109483594	12	-	27260156	L33	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.03157422562131362	[63]	[54,30,33,76]	0	hSpCas9	negative selection	7033771
109483691	109483714	12	+	27260156	L33	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.027074816705278032	[496]	[435,220,283,598]	0	hSpCas9	negative selection	7033772
109483951	109483974	12	+	27260156	L33	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.1513748124874041	[340]	[336,135,227,196]	-3	hSpCas9	negative selection	7033773
109483954	109483977	12	-	27260156	L33	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	-0.11599518826631972	[202]	[169,82,93,226]	-3	hSpCas9	negative selection	7098020
109486038	109486061	12	-	27260156	L33	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.007439010871191476	[1045]	[1180,415,613,1028]	0	hSpCas9	negative selection	7098021
109486029	109486052	12	+	27260156	L33	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	0.3054822626575188	[506]	[723,272,305,625]	6	hSpCas9	negative selection	7098022
109483571	109483594	12	-	27260156	K562	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.16562465075540578	[63]	[15,33,11,173]	2	hSpCas9	negative selection	7155022
109483691	109483714	12	+	27260156	K562	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.14905274527336998	[496]	[337,437,416,393]	-2	hSpCas9	negative selection	7155023
109483951	109483974	12	+	27260156	K562	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.6836963857058554	[340]	[717,527,519,227]	8	hSpCas9	negative selection	7155024
109483954	109483977	12	-	27260156	K562	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.1171848959011248	[202]	[286,165,178,158]	1	hSpCas9	negative selection	7219271
109486038	109486061	12	-	27260156	K562	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.4126063197822505	[1045]	[1548,1800,1119,597]	5	hSpCas9	negative selection	7219272
109486029	109486052	12	+	27260156	K562	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.24705322269643856	[506]	[511,311,288,405]	-3	hSpCas9	negative selection	7219273
109483571	109483594	12	-	27260156	HT29	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.4424846299726868	[63]	[106,53,143,111]	8	hSpCas9	negative selection	7276273
109483691	109483714	12	+	27260156	HT29	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.03791845059658877	[496]	[767,659,634,337]	-1	hSpCas9	negative selection	7276274
109483951	109483974	12	+	27260156	HT29	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.21389908452135092	[340]	[561,533,412,427]	4	hSpCas9	negative selection	7276275
109483954	109483977	12	-	27260156	HT29	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.21012038009467315	[202]	[321,309,301,218]	4	hSpCas9	negative selection	7340522
109486038	109486061	12	-	27260156	HT29	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.04234902624549619	[1045]	[1461,1352,1248,1193]	0	hSpCas9	negative selection	7340523
109486029	109486052	12	+	27260156	HT29	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.12372398256711076	[506]	[484,637,600,537]	-3	hSpCas9	negative selection	7340524
109483571	109483594	12	-	27260156	MHHES1	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.8299666755977428	[63]	[100,32,30,9]	-9	hSpCas9	negative selection	7397524
109483691	109483714	12	+	27260156	MHHES1	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.13042790018339	[496]	[497,827,289,458]	-2	hSpCas9	negative selection	7397525
109483951	109483974	12	+	27260156	MHHES1	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.07294937495108106	[340]	[671,311,389,283]	1	hSpCas9	negative selection	7397526
109483954	109483977	12	-	27260156	MHHES1	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.5269943531154065	[202]	[510,397,197,249]	8	hSpCas9	negative selection	7461773
109486038	109486061	12	-	27260156	MHHES1	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.23254731158191444	[1045]	[876,1367,923,870]	-4	hSpCas9	negative selection	7461774
109486029	109486052	12	+	27260156	MHHES1	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.05269668198482975	[506]	[775,423,684,363]	-1	hSpCas9	negative selection	7461775
109483571	109483594	12	-	27260156	MEWO	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.26856106015903114	[63]	[74,55,85]	6	hSpCas9	negative selection	7518775
109483691	109483714	12	+	27260156	MEWO	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.12190028094364178	[496]	[495,450,347]	-3	hSpCas9	negative selection	7518776
109483951	109483974	12	+	27260156	MEWO	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.2725678814761096	[340]	[404,349,404]	6	hSpCas9	negative selection	7518777
109483954	109483977	12	-	27260156	MEWO	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.1674082479261465	[202]	[305,166,184]	3	hSpCas9	negative selection	7583024
109486038	109486061	12	-	27260156	MEWO	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.2535152622725927	[1045]	[982,802,707]	-5	hSpCas9	negative selection	7583025
109486029	109486052	12	+	27260156	MEWO	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.10154328051325533	[506]	[529,279,533]	-2	hSpCas9	negative selection	7583026
109483571	109483594	12	-	27260156	LNCAPCLONEFGC	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.3277246815105088	[63]	[17,76,30,54]	-5	hSpCas9	negative selection	7640026
109483691	109483714	12	+	27260156	LNCAPCLONEFGC	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.26428573778682546	[496]	[429,356,480,246]	-4	hSpCas9	negative selection	7640027
109483951	109483974	12	+	27260156	LNCAPCLONEFGC	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.1408152329745304	[340]	[329,406,408,221]	2	hSpCas9	negative selection	7640028
109483954	109483977	12	-	27260156	LNCAPCLONEFGC	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	-0.1447364162148368	[202]	[123,156,208,182]	-2	hSpCas9	negative selection	7704275
109486038	109486061	12	-	27260156	LNCAPCLONEFGC	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.29848714718380875	[1045]	[578,921,925,670]	-5	hSpCas9	negative selection	7704276
109486029	109486052	12	+	27260156	LNCAPCLONEFGC	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	0.1949134027316909	[506]	[601,413,529,562]	3	hSpCas9	negative selection	7704277
109483571	109483594	12	-	27260156	PANC0327	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.23839954423443066	[63]	[50,32,74,35]	-4	hSpCas9	negative selection	7761277
109483691	109483714	12	+	27260156	PANC0327	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.04058652418940874	[496]	[441,346,474,564]	0	hSpCas9	negative selection	7761278
109483951	109483974	12	+	27260156	PANC0327	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.46760804893508007	[340]	[226,264,254,123]	-6	hSpCas9	negative selection	7761279
109483954	109483977	12	-	27260156	PANC0327	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.22004542104249003	[202]	[269,169,131,277]	3	hSpCas9	negative selection	7825526
109486038	109486061	12	-	27260156	PANC0327	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.25495302391619656	[1045]	[1310,1100,1331,708]	4	hSpCas9	negative selection	7825527
109486029	109486052	12	+	27260156	PANC0327	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	0.05923735745104414	[506]	[575,356,434,531]	0	hSpCas9	negative selection	7825528
109483571	109483594	12	-	27260156	NCIH2009	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.7667409652385375	[63]	[183,121,156]	9	hSpCas9	negative selection	7882528
109483691	109483714	12	+	27260156	NCIH2009	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.08163290812125935	[496]	[960,783,501]	1	hSpCas9	negative selection	7882529
109483951	109483974	12	+	27260156	NCIH2009	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.5244783897491825	[340]	[331,344,315]	-6	hSpCas9	negative selection	7882530
109483954	109483977	12	-	27260156	NCIH2009	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	-0.1938791929403778	[202]	[273,280,192]	-3	hSpCas9	negative selection	7946777
109486038	109486061	12	-	27260156	NCIH2009	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.14851665186567242	[1045]	[1589,1253,1163]	-2	hSpCas9	negative selection	7946778
109486029	109486052	12	+	27260156	NCIH2009	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.22703363223912343	[506]	[501,616,674]	-3	hSpCas9	negative selection	7946779
109483571	109483594	12	-	27260156	NCIH1373	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.7362578482766278	[63]	[25,20,88,8]	-6	hSpCas9	negative selection	8003779
109483691	109483714	12	+	27260156	NCIH1373	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.1151392264406111	[496]	[704,497,502,194]	1	hSpCas9	negative selection	8003780
109483951	109483974	12	+	27260156	NCIH1373	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.5555033241196385	[340]	[515,166,145,68]	-5	hSpCas9	negative selection	8003781
109483954	109483977	12	-	27260156	NCIH1373	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.2272161111720742	[202]	[146,339,244,80]	2	hSpCas9	negative selection	8068028
109486038	109486061	12	-	27260156	NCIH1373	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.4181196930832751	[1045]	[1913,1375,1084,523]	4	hSpCas9	negative selection	8068029
109486029	109486052	12	+	27260156	NCIH1373	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.30892650797912535	[506]	[560,405,339,145]	-3	hSpCas9	negative selection	8068030
109483571	109483594	12	-	27260156	PATU8902	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.15986117948176792	[63]	[154,18,79,60]	-2	hSpCas9	negative selection	8125030
109483691	109483714	12	+	27260156	PATU8902	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.15442134654376727	[496]	[515,1176,185,1431]	1	hSpCas9	negative selection	8125031
109483951	109483974	12	+	27260156	PATU8902	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.11098435899946457	[340]	[286,927,389,473]	1	hSpCas9	negative selection	8125032
109483954	109483977	12	-	27260156	PATU8902	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.2021004622661413	[202]	[345,283,246,456]	2	hSpCas9	negative selection	8189279
109486038	109486061	12	-	27260156	PATU8902	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.430878514606853	[1045]	[1434,789,615,1656]	-4	hSpCas9	negative selection	8189280
109486029	109486052	12	+	27260156	PATU8902	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.058265456128705165	[506]	[1116,669,404,566]	0	hSpCas9	negative selection	8189281
109483571	109483594	12	-	27260156	PANC1	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.8570655820978361	[63]	[265,28,45,45]	9	hSpCas9	negative selection	8246281
109483691	109483714	12	+	27260156	PANC1	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.04260032441901355	[496]	[417,462,309,460]	0	hSpCas9	negative selection	8246282
109483951	109483974	12	+	27260156	PANC1	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.521858529191813	[340]	[437,359,480,388]	8	hSpCas9	negative selection	8246283
109483954	109483977	12	-	27260156	PANC1	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.20703073352607815	[202]	[178,419,145,115]	3	hSpCas9	negative selection	8310530
109486038	109486061	12	-	27260156	PANC1	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.0064262558023244765	[1045]	[989,988,919,738]	0	hSpCas9	negative selection	8310531
109486029	109486052	12	+	27260156	PANC1	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	0.4080446300580261	[506]	[459,752,516,604]	6	hSpCas9	negative selection	8310532
109483571	109483594	12	-	27260156	PANC0813	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.7293602671043984	[63]	[112,26,12,34]	-8	hSpCas9	negative selection	8367532
109483691	109483714	12	+	27260156	PANC0813	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.12194961206494913	[496]	[668,740,608,529]	2	hSpCas9	negative selection	8367533
109483951	109483974	12	+	27260156	PANC0813	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.1832301714588886	[340]	[516,277,390,245]	-3	hSpCas9	negative selection	8367534
109483954	109483977	12	-	27260156	PANC0813	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.24162052687271984	[202]	[213,206,372,324]	4	hSpCas9	negative selection	8431781
109486038	109486061	12	-	27260156	PANC0813	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.022171745999723935	[1045]	[1146,1371,1483,991]	0	hSpCas9	negative selection	8431782
109486029	109486052	12	+	27260156	PANC0813	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	0.14815384813530275	[506]	[619,467,969,582]	2	hSpCas9	negative selection	8431783
109483571	109483594	12	-	27260156	RDES	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.4853018166417127	[63]	[63,60,39,36]	-7	hSpCas9	negative selection	8488783
109483691	109483714	12	+	27260156	RDES	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.15249354176400748	[496]	[363,489,532,722]	-3	hSpCas9	negative selection	8488784
109483951	109483974	12	+	27260156	RDES	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.3056146969063764	[340]	[295,271,321,388]	-5	hSpCas9	negative selection	8488785
109483954	109483977	12	-	27260156	RDES	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.0979341854292477	[202]	[165,191,362,308]	1	hSpCas9	negative selection	8553032
109486038	109486061	12	-	27260156	RDES	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.22593995240678322	[1045]	[813,952,1195,1207]	-4	hSpCas9	negative selection	8553033
109486029	109486052	12	+	27260156	RDES	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.16386368582706334	[506]	[435,572,552,516]	-3	hSpCas9	negative selection	8553034
109483571	109483594	12	-	27260156	PC3	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.6405656753281921	[63]	[47,12,243,172]	9	hSpCas9	negative selection	8610034
109483691	109483714	12	+	27260156	PC3	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.3599801746875889	[496]	[251,390,686,348]	-7	hSpCas9	negative selection	8610035
109483951	109483974	12	+	27260156	PC3	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.3887777396693208	[340]	[321,265,768,570]	7	hSpCas9	negative selection	8610036
109483954	109483977	12	-	27260156	PC3	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.41423819410283713	[202]	[128,319,550,223]	8	hSpCas9	negative selection	8674283
109486038	109486061	12	-	27260156	PC3	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.12669755519893888	[1045]	[611,742,1487,1266]	-3	hSpCas9	negative selection	8674284
109486029	109486052	12	+	27260156	PC3	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	0.13083932877671506	[506]	[425,482,842,569]	3	hSpCas9	negative selection	8674285
109483571	109483594	12	-	27260156	PATU8988T	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.9731141640186678	[63]	[13,77,13,23]	-8	hSpCas9	negative selection	8731285
109483691	109483714	12	+	27260156	PATU8988T	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.08782802186611209	[496]	[362,507,412,535]	-1	hSpCas9	negative selection	8731286
109483951	109483974	12	+	27260156	PATU8988T	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.6233720552058774	[340]	[486,536,453,559]	8	hSpCas9	negative selection	8731287
109483954	109483977	12	-	27260156	PATU8988T	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.12821433696624962	[202]	[208,286,77,298]	2	hSpCas9	negative selection	8795534
109486038	109486061	12	-	27260156	PATU8988T	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.022140935617301905	[1045]	[1157,1225,808,925]	0	hSpCas9	negative selection	8795535
109486029	109486052	12	+	27260156	PATU8988T	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	0.14579339302969196	[506]	[425,785,498,474]	2	hSpCas9	negative selection	8795536
109483571	109483594	12	-	27260156	T47D	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.22398758735037827	[63]	[144,64,73,65]	5	hSpCas9	negative selection	8852536
109483691	109483714	12	+	27260156	T47D	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.12741893494007128	[496]	[555,518,603,437]	-3	hSpCas9	negative selection	8852537
109483951	109483974	12	+	27260156	T47D	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.293858696525087	[340]	[495,515,446,486]	6	hSpCas9	negative selection	8852538
109483954	109483977	12	-	27260156	T47D	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.31094038385806744	[202]	[283,228,304,362]	6	hSpCas9	negative selection	8916785
109486038	109486061	12	-	27260156	T47D	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.1734921454073709	[1045]	[952,985,1179,1212]	-4	hSpCas9	negative selection	8916786
109486029	109486052	12	+	27260156	T47D	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	0.015140355437286979	[506]	[716,498,594,584]	0	hSpCas9	negative selection	8916787
109483571	109483594	12	-	27260156	SU8686	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.6788351259901284	[63]	[118,43,93,163]	9	hSpCas9	negative selection	8973787
109483691	109483714	12	+	27260156	SU8686	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.038450680163528886	[496]	[452,479,563,539]	0	hSpCas9	negative selection	8973788
109483951	109483974	12	+	27260156	SU8686	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.10573201234550694	[340]	[254,342,401,488]	1	hSpCas9	negative selection	8973789
109483954	109483977	12	-	27260156	SU8686	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.11141725820440462	[202]	[173,194,272,238]	1	hSpCas9	negative selection	9038036
109486038	109486061	12	-	27260156	SU8686	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.10114676324957395	[1045]	[860,905,990,1152]	-2	hSpCas9	negative selection	9038037
109486029	109486052	12	+	27260156	SU8686	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.035589735261723945	[506]	[469,440,547,512]	0	hSpCas9	negative selection	9038038
109483571	109483594	12	-	27260156	SKES1	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.07149326222739072	[63]	[93,46,37,65]	-1	hSpCas9	negative selection	9095038
109483691	109483714	12	+	27260156	SKES1	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.4606380574555626	[496]	[326,414,404,298]	-7	hSpCas9	negative selection	9095039
109483951	109483974	12	+	27260156	SKES1	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	-0.03883796561150216	[340]	[476,311,288,268]	-1	hSpCas9	negative selection	9095040
109483954	109483977	12	-	27260156	SKES1	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.35528592331143505	[202]	[341,211,260,227]	7	hSpCas9	negative selection	9159287
109486038	109486061	12	-	27260156	SKES1	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.06162559784311772	[1045]	[1136,908,1052,907]	-1	hSpCas9	negative selection	9159288
109486029	109486052	12	+	27260156	SKES1	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.16118480550348732	[506]	[503,458,438,414]	-4	hSpCas9	negative selection	9159289
109483571	109483594	12	-	27260156	TOV112D	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	0.0847816496190954	[63]	[147,7,83,24]	1	hSpCas9	negative selection	9216289
109483691	109483714	12	+	27260156	TOV112D	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.10320015443361634	[496]	[323,1057,161,443]	-2	hSpCas9	negative selection	9216290
109483951	109483974	12	+	27260156	TOV112D	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.14573255120671258	[340]	[411,630,231,302]	3	hSpCas9	negative selection	9216291
109483954	109483977	12	-	27260156	TOV112D	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.8435403424221478	[202]	[446,326,340,341]	9	hSpCas9	negative selection	9280538
109486038	109486061	12	-	27260156	TOV112D	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.009437812315405969	[1045]	[1098,1503,841,840]	0	hSpCas9	negative selection	9280539
109486029	109486052	12	+	27260156	TOV112D	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	0.12961678314237904	[506]	[439,1102,422,384]	2	hSpCas9	negative selection	9280540
109483571	109483594	12	-	27260156	TC71	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.08877186866876619	[63]	[17,133,40,66]	-2	hSpCas9	negative selection	9337540
109483691	109483714	12	+	27260156	TC71	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	0.006387221235904933	[496]	[561,559,528,485]	0	hSpCas9	negative selection	9337541
109483951	109483974	12	+	27260156	TC71	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.20199565474780468	[340]	[365,410,363,551]	5	hSpCas9	negative selection	9337542
109483954	109483977	12	-	27260156	TC71	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.21385497438376577	[202]	[216,310,289,186]	5	hSpCas9	negative selection	9401789
109486038	109486061	12	-	27260156	TC71	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	-0.06615800997987997	[1045]	[929,1144,1106,1105]	-2	hSpCas9	negative selection	9401790
109486029	109486052	12	+	27260156	TC71	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.19564776593506872	[506]	[328,488,605,472]	-5	hSpCas9	negative selection	9401791
109483571	109483594	12	-	27260156	TC32	viability	ATCGATGAACCATGCTCTCGAGG	UBE3B	ENSG00000151148	-0.03913837459825409	[63]	[50,27,110,62]	0	hSpCas9	negative selection	9458791
109483691	109483714	12	+	27260156	TC32	viability	GTCGACTGCAGAGAGATATCAGG	UBE3B	ENSG00000151148	-0.10979372993653322	[496]	[329,366,495,568]	-2	hSpCas9	negative selection	9458792
109483951	109483974	12	+	27260156	TC32	viability	GTTCCTATTCAGAATCAAAGAGG	UBE3B	ENSG00000151148	0.057653676370813034	[340]	[233,264,464,416]	1	hSpCas9	negative selection	9458793
109483954	109483977	12	-	27260156	TC32	viability	TATCCTCTTTGATTCTGAATAGG	UBE3B	ENSG00000151148	0.3595323097268289	[202]	[239,182,350,231]	6	hSpCas9	negative selection	9523040
109486038	109486061	12	-	27260156	TC32	viability	TCTCAGCATCCATGCTGCTCAGG	UBE3B	ENSG00000151148	0.16665804005037765	[1045]	[1096,836,1294,1260]	3	hSpCas9	negative selection	9523041
109486029	109486052	12	+	27260156	TC32	viability	TCGCAGCATCCTGAGCAGCATGG	UBE3B	ENSG00000151148	-0.16113660978219885	[506]	[371,299,546,542]	-3	hSpCas9	negative selection	9523042
109483560	109483583	12	-	27869803	HPAFII	viability after 27 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	-0.1410389007647841	[273]	[86,166,NaN]	-1	hSpCas9	negative selection	9545074
109486484	109486507	12	-	27869803	HPAFII	viability after 27 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	1.505028901439553	[69]	[74,128,NaN]	9	hSpCas9	negative selection	9545075
109489963	109489986	12	+	27869803	HPAFII	viability after 27 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	0.5586126037928446	[225]	[150,194,NaN]	4	hSpCas9	negative selection	9545076
109490548	109490571	12	+	27869803	HPAFII	viability after 27 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	0.24915876261063363	[149]	[102,85,NaN]	2	hSpCas9	negative selection	9545077
109491072	109491095	12	-	27869803	HPAFII	viability after 27 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	1.0871529098201018	[177]	[170,221,NaN]	8	hSpCas9	negative selection	9545078
109499778	109499801	12	-	27869803	HPAFII	viability after 27 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	-0.23078885723745413	[389]	[189,161,NaN]	-2	hSpCas9	negative selection	9545079
109483560	109483583	12	-	27869803	HPAFII	viability after 15 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.0398715383825638	[273]	[245,337,NaN]	0	hSpCas9	negative selection	9627523
109486484	109486507	12	-	27869803	HPAFII	viability after 15 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	1.631661612287077	[69]	[250,221,NaN]	9	hSpCas9	negative selection	9627524
109489963	109489986	12	+	27869803	HPAFII	viability after 15 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	-0.4084812653254969	[225]	[145,205,NaN]	-4	hSpCas9	negative selection	9627525
109490548	109490571	12	+	27869803	HPAFII	viability after 15 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	0.2534699571476095	[149]	[259,149,NaN]	3	hSpCas9	negative selection	9627526
109491072	109491095	12	-	27869803	HPAFII	viability after 15 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	-0.6419673941246409	[177]	[55,163,NaN]	-6	hSpCas9	negative selection	9627527
109499778	109499801	12	-	27869803	HPAFII	viability after 15 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	-0.011845570747665568	[389]	[596,302,NaN]	0	hSpCas9	negative selection	9627528
109483560	109483583	12	-	27869803	ASPC1	viability after 36 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	-0.8182805548711862	[570]	[49,160,117]	-7	hSpCas9	negative selection	9709972
109486484	109486507	12	-	27869803	ASPC1	viability after 36 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.6815418942383016	[202]	[292,87,6]	6	hSpCas9	negative selection	9709973
109489963	109489986	12	+	27869803	ASPC1	viability after 36 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	-0.6100637412702611	[551]	[192,80,113]	-6	hSpCas9	negative selection	9709974
109490548	109490571	12	+	27869803	ASPC1	viability after 36 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	-0.5429020617134326	[367]	[22,135,94]	-5	hSpCas9	negative selection	9709975
109491072	109491095	12	-	27869803	ASPC1	viability after 36 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	-0.9264504910898999	[332]	[86,106,5]	-7	hSpCas9	negative selection	9709976
109499778	109499801	12	-	27869803	ASPC1	viability after 36 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.8096727324460748	[664]	[475,270,461]	7	hSpCas9	negative selection	9709977
109483560	109483583	12	-	27869803	PATU8988S	viability after 35 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.45070495537550825	[440]	[349,134,NaN]	5	hSpCas9	negative selection	9792421
109486484	109486507	12	-	27869803	PATU8988S	viability after 35 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.06796195868926702	[206]	[93,64,NaN]	0	hSpCas9	negative selection	9792422
109489963	109489986	12	+	27869803	PATU8988S	viability after 35 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	-0.4905659301653622	[486]	[183,94,NaN]	-5	hSpCas9	negative selection	9792423
109490548	109490571	12	+	27869803	PATU8988S	viability after 35 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	-0.48526196607093974	[333]	[137,53,NaN]	-5	hSpCas9	negative selection	9792424
109491072	109491095	12	-	27869803	PATU8988S	viability after 35 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	0.5777955519511613	[309]	[339,31,NaN]	6	hSpCas9	negative selection	9792425
109499778	109499801	12	-	27869803	PATU8988S	viability after 35 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.2710616437119263	[725]	[279,425,NaN]	3	hSpCas9	negative selection	9792426
109483560	109483583	12	-	27869803	PATU8988S	viability after 31 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.18802570492304072	[440]	[220,173,NaN]	2	hSpCas9	negative selection	9874870
109486484	109486507	12	-	27869803	PATU8988S	viability after 31 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.5599317081466718	[206]	[122,119,NaN]	6	hSpCas9	negative selection	9874871
109489963	109489986	12	+	27869803	PATU8988S	viability after 31 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	-0.6089215206539944	[486]	[158,86,NaN]	-6	hSpCas9	negative selection	9874872
109490548	109490571	12	+	27869803	PATU8988S	viability after 31 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	-0.744662803031234	[333]	[93,60,NaN]	-7	hSpCas9	negative selection	9874873
109491072	109491095	12	-	27869803	PATU8988S	viability after 31 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	0.6272748213431436	[309]	[259,102,NaN]	7	hSpCas9	negative selection	9874874
109499778	109499801	12	-	27869803	PATU8988S	viability after 31 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.30833843934823824	[725]	[295,437,NaN]	4	hSpCas9	negative selection	9874875
109483560	109483583	12	-	27869803	HPAFII	viability after 35 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	0.3419320629527083	[273]	[29,339,NaN]	2	hSpCas9	negative selection	9957319
109486484	109486507	12	-	27869803	HPAFII	viability after 35 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	1.989361056387739	[69]	[24,270,NaN]	9	hSpCas9	negative selection	9957320
109489963	109489986	12	+	27869803	HPAFII	viability after 35 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	0.666661859546374	[225]	[119,250,NaN]	4	hSpCas9	negative selection	9957321
109490548	109490571	12	+	27869803	HPAFII	viability after 35 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	-0.0641100632085263	[149]	[50,96,NaN]	0	hSpCas9	negative selection	9957322
109491072	109491095	12	-	27869803	HPAFII	viability after 35 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	1.9196652897082525	[177]	[307,377,NaN]	9	hSpCas9	negative selection	9957323
109499778	109499801	12	-	27869803	HPAFII	viability after 35 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.048049854960486194	[389]	[94,326,NaN]	0	hSpCas9	negative selection	9957324
109483560	109483583	12	-	27869803	HPAFII	viability after 31 days	ATGCTCTCGAGGTCTGAGACAGG	UBE3B	ENSG00000151148	-0.0016264774514750668	[273]	[32,284,NaN]	0	hSpCas9	negative selection	10039768
109486484	109486507	12	-	27869803	HPAFII	viability after 31 days	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	1.7071442300045818	[69]	[44,218,NaN]	9	hSpCas9	negative selection	10039769
109489963	109489986	12	+	27869803	HPAFII	viability after 31 days	ATGGGACATCTCAACCAGCATGG	UBE3B	ENSG00000151148	0.2582015811286921	[225]	[155,146,NaN]	1	hSpCas9	negative selection	10039770
109490548	109490571	12	+	27869803	HPAFII	viability after 31 days	GGTGGTCCGTTGGCAGAAGCTGG	UBE3B	ENSG00000151148	0.42126191663118445	[149]	[128,94,NaN]	3	hSpCas9	negative selection	10039771
109491072	109491095	12	-	27869803	HPAFII	viability after 31 days	CCTTTGGATAGACAAGGACGGGG	UBE3B	ENSG00000151148	1.4513760011598156	[177]	[187,365,NaN]	9	hSpCas9	negative selection	10039772
109499778	109499801	12	-	27869803	HPAFII	viability after 31 days	CAGATTGGGAGAACCAGCCAAGG	UBE3B	ENSG00000151148	0.0250911765658276	[389]	[126,326,NaN]	0	hSpCas9	negative selection	10039773
109486484	109486507	12	-	28162770	P31FUJ	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.6478397036932222	[163]	[122]	-5	hSpCas9	negative selection	10260503
109486554	109486577	12	+	28162770	P31FUJ	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	0.9177574721610027	[49]	[110]	9	hSpCas9	negative selection	10260504
109486508	109486531	12	-	28162770	P31FUJ	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-0.7886183594760182	[146]	[99]	-6	hSpCas9	negative selection	10260505
109489977	109490000	12	-	28162770	P31FUJ	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-0.6598123453592986	[120]	[89]	-5	hSpCas9	negative selection	10260506
109483623	109483646	12	+	28162770	P31FUJ	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	-0.05771549785628727	[61]	[69]	0	hSpCas9	negative selection	10260507
109488627	109488650	12	+	28162770	P31FUJ	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.3563000266677015	[231]	[348]	4	hSpCas9	negative selection	10260508
109483659	109483682	12	-	28162770	P31FUJ	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	0.8262637364501386	[334]	[697]	8	hSpCas9	negative selection	10260509
109483671	109483694	12	-	28162770	P31FUJ	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	-0.5574244084710039	[133]	[106]	-5	hSpCas9	negative selection	10260510
109486050	109486073	12	+	28162770	P31FUJ	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	-0.3089738848997826	[349]	[331]	-3	hSpCas9	negative selection	10260511
109488592	109488615	12	-	28162770	P31FUJ	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	0.42561274133024896	[350]	[553]	5	hSpCas9	negative selection	10260512
109486484	109486507	12	-	28162770	TF1	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10429869
109486554	109486577	12	+	28162770	TF1	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	NaN	[NaN]	[155]	1	hSpCas9	negative selection	10429870
109486508	109486531	12	-	28162770	TF1	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	NaN	[NaN]	[35]	1	hSpCas9	negative selection	10429871
109489977	109490000	12	-	28162770	TF1	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	NaN	[NaN]	[83]	1	hSpCas9	negative selection	10429872
109483623	109483646	12	+	28162770	TF1	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10429873
109488627	109488650	12	+	28162770	TF1	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	NaN	[NaN]	[310]	1	hSpCas9	negative selection	10429874
109483659	109483682	12	-	28162770	TF1	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	NaN	[NaN]	[480]	1	hSpCas9	negative selection	10429875
109483671	109483694	12	-	28162770	TF1	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	NaN	[NaN]	[207]	1	hSpCas9	negative selection	10429876
109486050	109486073	12	+	28162770	TF1	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	NaN	[NaN]	[225]	1	hSpCas9	negative selection	10429877
109488592	109488615	12	-	28162770	TF1	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	NaN	[NaN]	[173]	1	hSpCas9	negative selection	10429878
109486484	109486507	12	-	28162770	SKM1	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.08873096388090707	[24]	[46]	0	hSpCas9	negative selection	10599235
109486554	109486577	12	+	28162770	SKM1	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	0.9853532240355987	[15]	[55]	8	hSpCas9	negative selection	10599236
109486508	109486531	12	-	28162770	SKM1	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-0.5726422290852882	[52]	[62]	-4	hSpCas9	negative selection	10599237
109489977	109490000	12	-	28162770	SKM1	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-1.1630386158570727	[18]	[14]	-7	hSpCas9	negative selection	10599238
109483623	109483646	12	+	28162770	SKM1	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	1.2577254944487288	[21]	[92]	9	hSpCas9	negative selection	10599239
109488627	109488650	12	+	28162770	SKM1	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.08607581253695518	[80]	[151]	0	hSpCas9	negative selection	10599240
109483659	109483682	12	-	28162770	SKM1	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	1.3108101304032074	[69]	[306]	9	hSpCas9	negative selection	10599241
109483671	109483694	12	-	28162770	SKM1	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	-0.7813597135246596	[34]	[35]	-5	hSpCas9	negative selection	10599242
109486050	109486073	12	+	28162770	SKM1	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	0.2668075689358505	[62]	[133]	2	hSpCas9	negative selection	10599243
109488592	109488615	12	-	28162770	SKM1	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	0.17799830197799454	[67]	[135]	1	hSpCas9	negative selection	10599244
109486484	109486507	12	-	28162770	SKM1	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.08873096388090707	[24]	[46]	0	hSpCas9	negative selection	10768601
109486554	109486577	12	+	28162770	SKM1	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	0.9853532240355987	[15]	[55]	8	hSpCas9	negative selection	10768602
109486508	109486531	12	-	28162770	SKM1	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-0.5726422290852882	[52]	[62]	-4	hSpCas9	negative selection	10768603
109489977	109490000	12	-	28162770	SKM1	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-1.1630386158570727	[18]	[14]	-7	hSpCas9	negative selection	10768604
109483623	109483646	12	+	28162770	SKM1	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	1.2577254944487288	[21]	[92]	9	hSpCas9	negative selection	10768605
109488627	109488650	12	+	28162770	SKM1	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.08607581253695518	[80]	[151]	0	hSpCas9	negative selection	10768606
109483659	109483682	12	-	28162770	SKM1	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	1.3108101304032074	[69]	[306]	9	hSpCas9	negative selection	10768607
109483671	109483694	12	-	28162770	SKM1	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	-0.7813597135246596	[34]	[35]	-5	hSpCas9	negative selection	10768608
109486050	109486073	12	+	28162770	SKM1	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	0.2668075689358505	[62]	[133]	2	hSpCas9	negative selection	10768609
109488592	109488615	12	-	28162770	SKM1	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	0.17799830197799454	[67]	[135]	1	hSpCas9	negative selection	10768610
109486484	109486507	12	-	28162770	PL21	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.6114152960975694	[171]	[48]	-4	hSpCas9	negative selection	10937967
109486554	109486577	12	+	28162770	PL21	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	-1.7204259180162746	[52]	[6]	-8	hSpCas9	negative selection	10937968
109486508	109486531	12	-	28162770	PL21	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-0.5792612459972826	[229]	[66]	-4	hSpCas9	negative selection	10937969
109489977	109490000	12	-	28162770	PL21	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-1.3721118344822818	[112]	[18]	-7	hSpCas9	negative selection	10937970
109483623	109483646	12	+	28162770	PL21	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	-0.334196813161868	[83]	[28]	-2	hSpCas9	negative selection	10937971
109488627	109488650	12	+	28162770	PL21	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	-0.39932245592695104	[199]	[65]	-3	hSpCas9	negative selection	10937972
109483659	109483682	12	-	28162770	PL21	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	0.5554048932507951	[307]	[196]	5	hSpCas9	negative selection	10937973
109483671	109483694	12	-	28162770	PL21	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	-0.36754489480000063	[82]	[27]	-3	hSpCas9	negative selection	10937974
109486050	109486073	12	+	28162770	PL21	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	-0.022252806847127715	[272]	[116]	0	hSpCas9	negative selection	10937975
109488592	109488615	12	-	28162770	PL21	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	1.0468432040227498	[247]	[222]	8	hSpCas9	negative selection	10937976
109486484	109486507	12	-	28162770	P31FUJ	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.6478397036932222	[163]	[122]	-5	hSpCas9	negative selection	11107333
109486554	109486577	12	+	28162770	P31FUJ	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	0.9177574721610027	[49]	[110]	9	hSpCas9	negative selection	11107334
109486508	109486531	12	-	28162770	P31FUJ	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-0.7886183594760182	[146]	[99]	-6	hSpCas9	negative selection	11107335
109489977	109490000	12	-	28162770	P31FUJ	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-0.6598123453592986	[120]	[89]	-5	hSpCas9	negative selection	11107336
109483623	109483646	12	+	28162770	P31FUJ	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	-0.05771549785628727	[61]	[69]	0	hSpCas9	negative selection	11107337
109488627	109488650	12	+	28162770	P31FUJ	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.3563000266677015	[231]	[348]	4	hSpCas9	negative selection	11107338
109483659	109483682	12	-	28162770	P31FUJ	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	0.8262637364501386	[334]	[697]	8	hSpCas9	negative selection	11107339
109483671	109483694	12	-	28162770	P31FUJ	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	-0.5574244084710039	[133]	[106]	-5	hSpCas9	negative selection	11107340
109486050	109486073	12	+	28162770	P31FUJ	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	-0.3089738848997826	[349]	[331]	-3	hSpCas9	negative selection	11107341
109488592	109488615	12	-	28162770	P31FUJ	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	0.42561274133024896	[350]	[553]	5	hSpCas9	negative selection	11107342
109486484	109486507	12	-	28162770	OCIAML5	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	1.5450359144801402	[85]	[452]	9	hSpCas9	negative selection	11276699
109486554	109486577	12	+	28162770	OCIAML5	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	1.6426981208855806	[21]	[123]	9	hSpCas9	negative selection	11276700
109486508	109486531	12	-	28162770	OCIAML5	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	0.20548445169816165	[85]	[178]	1	hSpCas9	negative selection	11276701
109489977	109490000	12	-	28162770	OCIAML5	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-0.021991572306309548	[35]	[63]	0	hSpCas9	negative selection	11276702
109483623	109483646	12	+	28162770	OCIAML5	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	0.10353930977754966	[32]	[63]	0	hSpCas9	negative selection	11276703
109488627	109488650	12	+	28162770	OCIAML5	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.9880620923576134	[142]	[511]	8	hSpCas9	negative selection	11276704
109483659	109483682	12	-	28162770	OCIAML5	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	0.8848990233022093	[188]	[629]	7	hSpCas9	negative selection	11276705
109483671	109483694	12	-	28162770	OCIAML5	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	0.2579062711611344	[100]	[217]	2	hSpCas9	negative selection	11276706
109486050	109486073	12	+	28162770	OCIAML5	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	0.2582154841509138	[213]	[461]	2	hSpCas9	negative selection	11276707
109488592	109488615	12	-	28162770	OCIAML5	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	0.11252809300480426	[164]	[321]	0	hSpCas9	negative selection	11276708
109486484	109486507	12	-	28162770	EOL1	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.9416889043919285	[250]	[253]	7	hSpCas9	negative selection	11446065
109486554	109486577	12	+	28162770	EOL1	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	0.7319026936281385	[55]	[48]	6	hSpCas9	negative selection	11446066
109486508	109486531	12	-	28162770	EOL1	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-0.6679092656975458	[385]	[127]	-5	hSpCas9	negative selection	11446067
109489977	109490000	12	-	28162770	EOL1	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-0.818294388932341	[163]	[48]	-5	hSpCas9	negative selection	11446068
109483623	109483646	12	+	28162770	EOL1	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	1.1188165919925945	[110]	[126]	8	hSpCas9	negative selection	11446069
109488627	109488650	12	+	28162770	EOL1	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	-0.02207113210144196	[450]	[233]	0	hSpCas9	negative selection	11446070
109483659	109483682	12	-	28162770	EOL1	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	0.132831973290521	[366]	[211]	1	hSpCas9	negative selection	11446071
109483671	109483694	12	-	28162770	EOL1	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	-1.8465110212640794	[156]	[22]	-8	hSpCas9	negative selection	11446072
109486050	109486073	12	+	28162770	EOL1	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	-0.12922348487044616	[327]	[157]	-1	hSpCas9	negative selection	11446073
109488592	109488615	12	-	28162770	EOL1	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	-0.25951151407541384	[358]	[157]	-2	hSpCas9	negative selection	11446074
109486484	109486507	12	-	28162770	MOLM13	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.5120891854551141	[224]	[231]	4	hSpCas9	negative selection	11615431
109486554	109486577	12	+	28162770	MOLM13	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	1.1877814623518437	[67]	[111]	8	hSpCas9	negative selection	11615432
109486508	109486531	12	-	28162770	MOLM13	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-0.6445853477138337	[319]	[147]	-4	hSpCas9	negative selection	11615433
109489977	109490000	12	-	28162770	MOLM13	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-0.6122809671394044	[147]	[69]	-4	hSpCas9	negative selection	11615434
109483623	109483646	12	+	28162770	MOLM13	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	0.4946067199203581	[106]	[108]	3	hSpCas9	negative selection	11615435
109488627	109488650	12	+	28162770	MOLM13	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.6871075550858832	[389]	[453]	5	hSpCas9	negative selection	11615436
109483659	109483682	12	-	28162770	MOLM13	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	0.17117184945449648	[311]	[253]	1	hSpCas9	negative selection	11615437
109483671	109483694	12	-	28162770	MOLM13	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	-0.9345950673911803	[266]	[100]	-5	hSpCas9	negative selection	11615438
109486050	109486073	12	+	28162770	MOLM13	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	-0.6223084274269994	[395]	[185]	-4	hSpCas9	negative selection	11615439
109488592	109488615	12	-	28162770	MOLM13	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	-0.3143348251893434	[312]	[181]	-2	hSpCas9	negative selection	11615440
109486484	109486507	12	-	28162770	HEL	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.013776929745833277	[185]	[117]	0	hSpCas9	negative selection	11784797
109486554	109486577	12	+	28162770	HEL	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	-0.8166927866369402	[43]	[15]	-5	hSpCas9	negative selection	11784798
109486508	109486531	12	-	28162770	HEL	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-0.7548535328190775	[273]	[103]	-5	hSpCas9	negative selection	11784799
109489977	109490000	12	-	28162770	HEL	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-0.57298985905508	[143]	[61]	-4	hSpCas9	negative selection	11784800
109483623	109483646	12	+	28162770	HEL	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	1.0068951622770168	[100]	[129]	8	hSpCas9	negative selection	11784801
109488627	109488650	12	+	28162770	HEL	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	1.24137626961859	[279]	[423]	9	hSpCas9	negative selection	11784802
109483659	109483682	12	-	28162770	HEL	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	1.2798240637976455	[298]	[464]	9	hSpCas9	negative selection	11784803
109483671	109483694	12	-	28162770	HEL	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	0.5217234310389909	[173]	[159]	4	hSpCas9	negative selection	11784804
109486050	109486073	12	+	28162770	HEL	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	-0.3728580230506615	[278]	[137]	-3	hSpCas9	negative selection	11784805
109488592	109488615	12	-	28162770	HEL	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	-0.3614734192865575	[342]	[170]	-3	hSpCas9	negative selection	11784806
109486484	109486507	12	-	28162770	MV411	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.6850176187127075	[126]	[171]	6	hSpCas9	negative selection	11954163
109486554	109486577	12	+	28162770	MV411	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	-0.22204773251844512	[53]	[38]	-2	hSpCas9	negative selection	11954164
109486508	109486531	12	-	28162770	MV411	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-1.4915585786108019	[236]	[70]	-7	hSpCas9	negative selection	11954165
109489977	109490000	12	-	28162770	MV411	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-1.771421476468541	[76]	[18]	-8	hSpCas9	negative selection	11954166
109483623	109483646	12	+	28162770	MV411	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	0.22697344822305965	[70]	[69]	2	hSpCas9	negative selection	11954167
109488627	109488650	12	+	28162770	MV411	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	-0.12792980306604762	[274]	[211]	-1	hSpCas9	negative selection	11954168
109483659	109483682	12	-	28162770	MV411	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	1.0663719917352625	[194]	[343]	8	hSpCas9	negative selection	11954169
109483671	109483694	12	-	28162770	MV411	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	-0.7172293761049439	[120]	[61]	-5	hSpCas9	negative selection	11954170
109486050	109486073	12	+	28162770	MV411	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	-0.6289877640986921	[245]	[133]	-4	hSpCas9	negative selection	11954171
109488592	109488615	12	-	28162770	MV411	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	0.7012640445762688	[210]	[288]	6	hSpCas9	negative selection	11954172
109486484	109486507	12	-	28162770	MONOMAC1	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	-0.4645171579245396	[129]	[107]	-4	hSpCas9	negative selection	12123529
109486554	109486577	12	+	28162770	MONOMAC1	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	-0.19703684705955382	[37]	[37]	-2	hSpCas9	negative selection	12123530
109486508	109486531	12	-	28162770	MONOMAC1	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-0.4582345944137303	[156]	[130]	-4	hSpCas9	negative selection	12123531
109489977	109490000	12	-	28162770	MONOMAC1	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	1.2152235675487166	[64]	[172]	9	hSpCas9	negative selection	12123532
109483623	109483646	12	+	28162770	MONOMAC1	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	0.08126431542755053	[46]	[56]	0	hSpCas9	negative selection	12123533
109488627	109488650	12	+	28162770	MONOMAC1	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.36169411208842284	[147]	[217]	3	hSpCas9	negative selection	12123534
109483659	109483682	12	-	28162770	MONOMAC1	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	-0.27557024960624305	[150]	[142]	-2	hSpCas9	negative selection	12123535
109483671	109483694	12	-	28162770	MONOMAC1	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	0.29556163551294284	[85]	[120]	3	hSpCas9	negative selection	12123536
109486050	109486073	12	+	28162770	MONOMAC1	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	0.02208044224403327	[188]	[219]	0	hSpCas9	negative selection	12123537
109488592	109488615	12	-	28162770	MONOMAC1	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	0.26386766097661896	[177]	[244]	2	hSpCas9	negative selection	12123538
109486484	109486507	12	-	28162770	OCIAML2	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.7709561613275977	[23]	[226]	7	hSpCas9	negative selection	12292895
109486554	109486577	12	+	28162770	OCIAML2	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	-0.20759541940836712	[9]	[47]	-2	hSpCas9	negative selection	12292896
109486508	109486531	12	-	28162770	OCIAML2	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	-1.7925579201295236	[49]	[79]	-8	hSpCas9	negative selection	12292897
109489977	109490000	12	-	28162770	OCIAML2	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-0.4092292805780179	[22]	[95]	-3	hSpCas9	negative selection	12292898
109483623	109483646	12	+	28162770	OCIAML2	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	0.42099401371304684	[18]	[140]	4	hSpCas9	negative selection	12292899
109488627	109488650	12	+	28162770	OCIAML2	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.6168330160081783	[47]	[407]	6	hSpCas9	negative selection	12292900
109483659	109483682	12	-	28162770	OCIAML2	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	0.42014110500308033	[47]	[355]	4	hSpCas9	negative selection	12292901
109483671	109483694	12	-	28162770	OCIAML2	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	-0.8331999046268697	[44]	[139]	-5	hSpCas9	negative selection	12292902
109486050	109486073	12	+	28162770	OCIAML2	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	-0.4706298252421614	[55]	[223]	-4	hSpCas9	negative selection	12292903
109488592	109488615	12	-	28162770	OCIAML2	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	0.028602801453110893	[51]	[293]	0	hSpCas9	negative selection	12292904
109486484	109486507	12	-	28162770	OCIAML3	viability	GAGGTCCTTAGAACAAGCCAGGG	UBE3B	ENSG00000151148	0.2360673582335244	[44]	[159]	2	hSpCas9	negative selection	12462261
109486554	109486577	12	+	28162770	OCIAML3	viability	TGATTTTCTCAAGCAGCTCAAGG	UBE3B	ENSG00000151148	-0.25297072248909624	[14]	[37]	-2	hSpCas9	negative selection	12462262
109486508	109486531	12	-	28162770	OCIAML3	viability	GATCTGTTGAATCCAAAGGAGGG	UBE3B	ENSG00000151148	0.2403143293337102	[52]	[188]	2	hSpCas9	negative selection	12462263
109489977	109490000	12	-	28162770	OCIAML3	viability	GCACAGAATAAAATCCATGCTGG	UBE3B	ENSG00000151148	-0.3665971442210908	[40]	[95]	-3	hSpCas9	negative selection	12462264
109483623	109483646	12	+	28162770	OCIAML3	viability	TGTGCAGAAGGAACGGGAGCGGG	UBE3B	ENSG00000151148	0.5814343660857151	[28]	[130]	5	hSpCas9	negative selection	12462265
109488627	109488650	12	+	28162770	OCIAML3	viability	CCTTCACAGACACTTCAACGTGG	UBE3B	ENSG00000151148	0.3064566861249224	[59]	[223]	3	hSpCas9	negative selection	12462266
109483659	109483682	12	-	28162770	OCIAML3	viability	GAAAACTCCGGACATGGGCCTGG	UBE3B	ENSG00000151148	0.544474313467268	[66]	[294]	5	hSpCas9	negative selection	12462267
109483671	109483694	12	-	28162770	OCIAML3	viability	GACTCCGACAGAGAAAACTCCGG	UBE3B	ENSG00000151148	-1.7460107337692128	[29]	[26]	-8	hSpCas9	negative selection	12462268
109486050	109486073	12	+	28162770	OCIAML3	viability	GGATGCTGAGAATGAGCCTAAGG	UBE3B	ENSG00000151148	0.05675691879273906	[49]	[156]	0	hSpCas9	negative selection	12462269
109488592	109488615	12	-	28162770	OCIAML3	viability	TGAGGTACAGGGTGATGAGTCGG	UBE3B	ENSG00000151148	0.6223102666026002	[84]	[394]	5	hSpCas9	negative selection	12462270