Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:50613
• Symbol:UBQLN3
• Description:ubiquilin 3

DataSource: http://genomecrispr.dkfz.de/#!/results/UBQLN3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
5509459	5509482	11	-	26472758	Jiyoye	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	0.2577977574676467	[121]	[109]	2	hSpCas9	negative selection	176740
5507886	5507909	11	-	26472758	Jiyoye	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	-0.05749288549757092	[68]	[49]	0	hSpCas9	negative selection	176741
5507761	5507784	11	+	26472758	Jiyoye	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	0.6828098241193007	[56]	[68]	5	hSpCas9	negative selection	176742
5509369	5509392	11	+	26472758	Jiyoye	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	-0.4303499215370211	[301]	[168]	-3	hSpCas9	negative selection	176743
5509276	5509299	11	+	26472758	Jiyoye	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	-0.14406650137128169	[147]	[100]	-1	hSpCas9	negative selection	176744
5508341	5508364	11	-	26472758	Jiyoye	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.012203505281135452	[237]	[180]	0	hSpCas9	negative selection	176745
5508285	5508308	11	-	26472758	Jiyoye	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	0.4496106478262699	[133]	[137]	3	hSpCas9	negative selection	176746
5508267	5508290	11	-	26472758	Jiyoye	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	1.5258198780044925	[34]	[75]	8	hSpCas9	negative selection	176747
5508146	5508169	11	+	26472758	Jiyoye	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	0.39489705172743683	[117]	[116]	3	hSpCas9	negative selection	176748
5508101	5508124	11	+	26472758	Jiyoye	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	0.6493762839225017	[92]	[109]	5	hSpCas9	negative selection	176749
5509459	5509482	11	-	26472758	KBM7	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	0.2893805508300692	[223,284]	[162,135]	3	hSpCas9	negative selection	367858
5507886	5507909	11	-	26472758	KBM7	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	0.2562533401782641	[411,344]	[132,281]	2	hSpCas9	negative selection	367859
5507761	5507784	11	+	26472758	KBM7	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	0.5266212782694543	[298,258]	[244,137]	6	hSpCas9	negative selection	367860
5509369	5509392	11	+	26472758	KBM7	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	-0.2546288230531054	[770,471]	[256,224]	-2	hSpCas9	negative selection	367861
5509276	5509299	11	+	26472758	KBM7	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	1.0254765890625825	[562,351]	[529,339]	9	hSpCas9	negative selection	367862
5508341	5508364	11	-	26472758	KBM7	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.4796237729593611	[1110,947]	[676,668]	5	hSpCas9	negative selection	367863
5508285	5508308	11	-	26472758	KBM7	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	0.14817705580946794	[345,458]	[208,217]	1	hSpCas9	negative selection	367864
5508267	5508290	11	-	26472758	KBM7	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	0.7236994398542278	[366,383]	[318,270]	7	hSpCas9	negative selection	367865
5508146	5508169	11	+	26472758	KBM7	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	0.22735779591473787	[635,424]	[315,261]	2	hSpCas9	negative selection	367866
5508101	5508124	11	+	26472758	KBM7	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	0.11797373090675581	[467,365]	[264,162]	1	hSpCas9	negative selection	367867
5509459	5509482	11	-	26472758	Raji	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	0.9345469385113837	[123]	[54]	8	hSpCas9	negative selection	558976
5507886	5507909	11	-	26472758	Raji	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	-0.983764352684596	[195]	[22]	-6	hSpCas9	negative selection	558977
5507761	5507784	11	+	26472758	Raji	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	1.0645704518346264	[170]	[82]	8	hSpCas9	negative selection	558978
5509369	5509392	11	+	26472758	Raji	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.6249907682929909	[284]	[101]	6	hSpCas9	negative selection	558979
5509276	5509299	11	+	26472758	Raji	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	0.7748081962867285	[203]	[80]	7	hSpCas9	negative selection	558980
5508341	5508364	11	-	26472758	Raji	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.4112516587159708	[417]	[128]	4	hSpCas9	negative selection	558981
5508285	5508308	11	-	26472758	Raji	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	-1.1656349590328166	[231]	[23]	-7	hSpCas9	negative selection	558982
5508267	5508290	11	-	26472758	Raji	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	0.16396706373996695	[149]	[38]	1	hSpCas9	negative selection	558983
5508146	5508169	11	+	26472758	Raji	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	0.13300934304909404	[278]	[70]	1	hSpCas9	negative selection	558984
5508101	5508124	11	+	26472758	Raji	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	0.10071980509258865	[216]	[53]	0	hSpCas9	negative selection	558985
5509459	5509482	11	-	26472758	K562	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	0.9270297923942522	[237]	[381]	7	hSpCas9	negative selection	750094
5507886	5507909	11	-	26472758	K562	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	-0.04142556107543288	[305]	[250]	0	hSpCas9	negative selection	750095
5507761	5507784	11	+	26472758	K562	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	1.0179101978577672	[233]	[399]	8	hSpCas9	negative selection	750096
5509369	5509392	11	+	26472758	K562	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	-0.06061758782214244	[466]	[377]	0	hSpCas9	negative selection	750097
5509276	5509299	11	+	26472758	K562	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	0.2518553165082285	[386]	[388]	2	hSpCas9	negative selection	750098
5508341	5508364	11	-	26472758	K562	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.014081359652100445	[697]	[594]	0	hSpCas9	negative selection	750099
5508285	5508308	11	-	26472758	K562	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	0.018389563691111527	[330]	[282]	0	hSpCas9	negative selection	750100
5508267	5508290	11	-	26472758	K562	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	1.2285123367570863	[227]	[450]	9	hSpCas9	negative selection	750101
5508146	5508169	11	+	26472758	K562	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	1.507121898269561	[362]	[870]	9	hSpCas9	negative selection	750102
5508101	5508124	11	+	26472758	K562	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	-0.37872696694259733	[267]	[173]	-3	hSpCas9	negative selection	750103
5507698	5507721	11	-	26627737	DLD1	viability	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	1.4221808702733387	[150]	[96,163,120]	9	hSpCas9	negative selection	778947
5507970	5507993	11	-	26627737	DLD1	viability	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.5515921756314279	[753]	[367,383,293]	5	hSpCas9	negative selection	778948
5508099	5508122	11	+	26627737	DLD1	viability	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.5865143460421739	[717]	[261,388,358]	6	hSpCas9	negative selection	778949
5508341	5508364	11	-	26627737	DLD1	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	-0.5589828774864605	[527]	[82,133,118]	-5	hSpCas9	negative selection	778950
5508842	5508865	11	-	26627737	DLD1	viability	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.05168542373848051	[862]	[319,260,259]	0	hSpCas9	negative selection	778951
5509006	5509029	11	+	26627737	DLD1	viability	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	0.03384004424325582	[660]	[425,163,64]	0	hSpCas9	negative selection	778952
5507698	5507721	11	-	26627737	GBM cells	viability after 5 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	0.19014517255013152	[75]	[44,47]	3	hSpCas9	negative selection	861262
5507970	5507993	11	-	26627737	GBM cells	viability after 5 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	-0.24960864982440223	[275]	[134,113]	-4	hSpCas9	negative selection	861263
5508099	5508122	11	+	26627737	GBM cells	viability after 5 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.5843091208041817	[392]	[303,327]	8	hSpCas9	negative selection	861264
5508341	5508364	11	-	26627737	GBM cells	viability after 5 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	-0.009163635673275106	[303]	[166,156]	0	hSpCas9	negative selection	861265
5508842	5508865	11	-	26627737	GBM cells	viability after 5 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.42825685950715053	[378]	[320,225]	6	hSpCas9	negative selection	861266
5509006	5509029	11	+	26627737	GBM cells	viability after 5 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	0.07114681961477698	[346]	[215,174]	1	hSpCas9	negative selection	861267
5507698	5507721	11	-	26627737	GBM cells	viability after 13 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	0.7611836804204368	[75]	[54,81]	8	hSpCas9	negative selection	943577
5507970	5507993	11	-	26627737	GBM cells	viability after 13 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.2451941162824825	[275]	[198,159]	3	hSpCas9	negative selection	943578
5508099	5508122	11	+	26627737	GBM cells	viability after 13 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.7894974911865089	[392]	[399,342]	8	hSpCas9	negative selection	943579
5508341	5508364	11	-	26627737	GBM cells	viability after 13 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.6309398433820569	[303]	[282,232]	7	hSpCas9	negative selection	943580
5508842	5508865	11	-	26627737	GBM cells	viability after 13 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.2342985031749717	[378]	[242,240]	3	hSpCas9	negative selection	943581
5509006	5509029	11	+	26627737	GBM cells	viability after 13 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	0.2537883988439895	[346]	[229,219]	3	hSpCas9	negative selection	943582
5507698	5507721	11	-	26627737	GBM cells	viability after 21 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	0.3928224577684256	[75]	[60,47]	4	hSpCas9	negative selection	1025892
5507970	5507993	11	-	26627737	GBM cells	viability after 21 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	-0.24314496735912366	[275]	[133,119]	-2	hSpCas9	negative selection	1025893
5508099	5508122	11	+	26627737	GBM cells	viability after 21 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.9881038073022812	[392]	[434,412]	8	hSpCas9	negative selection	1025894
5508341	5508364	11	-	26627737	GBM cells	viability after 21 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.5576459280907258	[303]	[240,244]	5	hSpCas9	negative selection	1025895
5508842	5508865	11	-	26627737	GBM cells	viability after 21 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.12003059291178308	[378]	[240,207]	1	hSpCas9	negative selection	1025896
5509006	5509029	11	+	26627737	GBM cells	viability after 21 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	0.8896724933735438	[346]	[377,322]	8	hSpCas9	negative selection	1025897
5507698	5507721	11	-	26627737	RPE1	viability after 9 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	1.1695556005848626	[226]	[120,209]	7	hSpCas9	negative selection	1108207
5507970	5507993	11	-	26627737	RPE1	viability after 9 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.28206357128152937	[1301]	[468,529]	2	hSpCas9	negative selection	1108208
5508099	5508122	11	+	26627737	RPE1	viability after 9 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.7688124366255277	[1405]	[594,949]	5	hSpCas9	negative selection	1108209
5508341	5508364	11	-	26627737	RPE1	viability after 9 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	-0.3504502937757309	[934]	[212,250]	-2	hSpCas9	negative selection	1108210
5508842	5508865	11	-	26627737	RPE1	viability after 9 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.8274322415777711	[1168]	[586,729]	5	hSpCas9	negative selection	1108211
5509006	5509029	11	+	26627737	RPE1	viability after 9 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	0.39171653114362615	[925]	[268,523]	2	hSpCas9	negative selection	1108212
5507698	5507721	11	-	26627737	RPE1	viability after 12 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	1.6450481467998552	[226]	[147,235]	8	hSpCas9	negative selection	1190522
5507970	5507993	11	-	26627737	RPE1	viability after 12 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.47940558059651495	[1301]	[493,480]	3	hSpCas9	negative selection	1190523
5508099	5508122	11	+	26627737	RPE1	viability after 12 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.9705575443992976	[1405]	[594,893]	6	hSpCas9	negative selection	1190524
5508341	5508364	11	-	26627737	RPE1	viability after 12 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	-0.46672950350731424	[934]	[139,225]	-3	hSpCas9	negative selection	1190525
5508842	5508865	11	-	26627737	RPE1	viability after 12 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.6791389575890363	[1168]	[396,614]	4	hSpCas9	negative selection	1190526
5509006	5509029	11	+	26627737	RPE1	viability after 12 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	0.7113428285877584	[925]	[350,466]	4	hSpCas9	negative selection	1190527
5507698	5507721	11	-	26627737	RPE1	viability after 15 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	2.1313912159954165	[226]	[261,299]	9	hSpCas9	negative selection	1272837
5507970	5507993	11	-	26627737	RPE1	viability after 15 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.4925663323096885	[1301]	[366,663]	3	hSpCas9	negative selection	1272838
5508099	5508122	11	+	26627737	RPE1	viability after 15 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.8362316823067618	[1405]	[732,687]	5	hSpCas9	negative selection	1272839
5508341	5508364	11	-	26627737	RPE1	viability after 15 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.028689794131404323	[934]	[308,231]	0	hSpCas9	negative selection	1272840
5508842	5508865	11	-	26627737	RPE1	viability after 15 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.9802986286871913	[1168]	[629,673]	6	hSpCas9	negative selection	1272841
5509006	5509029	11	+	26627737	RPE1	viability after 15 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	0.5659939322068231	[925]	[427,348]	3	hSpCas9	negative selection	1272842
5507698	5507721	11	-	26627737	RPE1	viability after 18 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	1.7724404656736086	[226]	[100,324]	8	hSpCas9	negative selection	1355152
5507970	5507993	11	-	26627737	RPE1	viability after 18 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.5652067323404217	[1301]	[297,756]	3	hSpCas9	negative selection	1355153
5508099	5508122	11	+	26627737	RPE1	viability after 18 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.7303227943325988	[1405]	[497,769]	4	hSpCas9	negative selection	1355154
5508341	5508364	11	-	26627737	RPE1	viability after 18 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.07048782741233733	[934]	[292,234]	0	hSpCas9	negative selection	1355155
5508842	5508865	11	-	26627737	RPE1	viability after 18 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.9190504159688642	[1168]	[538,657]	5	hSpCas9	negative selection	1355156
5509006	5509029	11	+	26627737	RPE1	viability after 18 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	0.908127354922722	[925]	[292,656]	5	hSpCas9	negative selection	1355157
5507698	5507721	11	-	26627737	HeLa	viability after 8 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	1.1327029261332626	[94]	[160,88,40]	8	hSpCas9	negative selection	1437467
5507970	5507993	11	-	26627737	HeLa	viability after 8 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	-0.3489199732607115	[593]	[213,145,247]	-3	hSpCas9	negative selection	1437468
5508099	5508122	11	+	26627737	HeLa	viability after 8 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	1.4762548808252527	[384]	[486,228,671]	9	hSpCas9	negative selection	1437469
5508341	5508364	11	-	26627737	HeLa	viability after 8 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.28782897147835873	[363]	[255,264,80]	2	hSpCas9	negative selection	1437470
5508842	5508865	11	-	26627737	HeLa	viability after 8 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.10973316117932297	[683]	[296,248,405]	1	hSpCas9	negative selection	1437471
5509006	5509029	11	+	26627737	HeLa	viability after 8 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	-1.0430082586230007	[565]	[116,135,105]	-8	hSpCas9	negative selection	1437472
5507698	5507721	11	-	26627737	HeLa	viability after 12 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	1.953704098298958	[94]	[218,134,105]	9	hSpCas9	negative selection	1519782
5507970	5507993	11	-	26627737	HeLa	viability after 12 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.40618761245111845	[593]	[271,441,247]	3	hSpCas9	negative selection	1519783
5508099	5508122	11	+	26627737	HeLa	viability after 12 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	1.5613909618219433	[384]	[654,319,454]	9	hSpCas9	negative selection	1519784
5508341	5508364	11	-	26627737	HeLa	viability after 12 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	-0.2468665239583734	[363]	[141,114,124]	-2	hSpCas9	negative selection	1519785
5508842	5508865	11	-	26627737	HeLa	viability after 12 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.1534120170048887	[683]	[378,361,198]	1	hSpCas9	negative selection	1519786
5509006	5509029	11	+	26627737	HeLa	viability after 12 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	-0.6047837687382225	[565]	[178,211,64]	-5	hSpCas9	negative selection	1519787
5507698	5507721	11	-	26627737	HeLa	viability after 15 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	1.750816268606345	[94]	[112,155,120]	9	hSpCas9	negative selection	1602097
5507970	5507993	11	-	26627737	HeLa	viability after 15 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.6263271449556416	[593]	[370,530,204]	5	hSpCas9	negative selection	1602098
5508099	5508122	11	+	26627737	HeLa	viability after 15 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	1.4450773434305892	[384]	[286,242,778]	8	hSpCas9	negative selection	1602099
5508341	5508364	11	-	26627737	HeLa	viability after 15 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.5069424971516147	[363]	[111,237,288]	4	hSpCas9	negative selection	1602100
5508842	5508865	11	-	26627737	HeLa	viability after 15 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	-0.03596806267179942	[683]	[299,223,291]	0	hSpCas9	negative selection	1602101
5509006	5509029	11	+	26627737	HeLa	viability after 15 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	-0.6002454582838482	[565]	[169,166,115]	-5	hSpCas9	negative selection	1602102
5507698	5507721	11	-	26627737	HeLa	viability after 18 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	1.7419170175240968	[94]	[75,126,120]	9	hSpCas9	negative selection	1684412
5507970	5507993	11	-	26627737	HeLa	viability after 18 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.6057669248945472	[593]	[243,432,204]	5	hSpCas9	negative selection	1684413
5508099	5508122	11	+	26627737	HeLa	viability after 18 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	1.4614326738240393	[384]	[198,204,778]	8	hSpCas9	negative selection	1684414
5508341	5508364	11	-	26627737	HeLa	viability after 18 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.47415312434406265	[363]	[73,186,288]	4	hSpCas9	negative selection	1684415
5508842	5508865	11	-	26627737	HeLa	viability after 18 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	-0.02582477022000551	[683]	[206,182,291]	0	hSpCas9	negative selection	1684416
5509006	5509029	11	+	26627737	HeLa	viability after 18 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	-0.6134255820664309	[565]	[113,134,115]	-5	hSpCas9	negative selection	1684417
5507698	5507721	11	-	26627737	HCT116	viability after 6 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	0.14221434081558604	[139]	[22,24]	0	hSpCas9	negative selection	1766727
5507970	5507993	11	-	26627737	HCT116	viability after 6 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	-0.6309794332643698	[795]	[45,99]	-4	hSpCas9	negative selection	1766728
5508099	5508122	11	+	26627737	HCT116	viability after 6 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.4065500262381191	[754]	[195,135]	2	hSpCas9	negative selection	1766729
5508341	5508364	11	-	26627737	HCT116	viability after 6 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.1401015334461885	[503]	[76,92]	0	hSpCas9	negative selection	1766730
5508842	5508865	11	-	26627737	HCT116	viability after 6 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.22537186080268468	[864]	[167,153]	1	hSpCas9	negative selection	1766731
5509006	5509029	11	+	26627737	HCT116	viability after 6 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	-1.3278559599286268	[1252]	[198,11]	-6	hSpCas9	negative selection	1766732
5507698	5507721	11	-	26627737	HCT116	viability after 8 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	-0.19776514523044375	[152]	[90,69,59]	-2	hSpCas9	negative selection	1849042
5507970	5507993	11	-	26627737	HCT116	viability after 8 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.1105660921834592	[410]	[313,194,225]	1	hSpCas9	negative selection	1849043
5508099	5508122	11	+	26627737	HCT116	viability after 8 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	-0.5671232707697093	[685]	[348,237,180]	-6	hSpCas9	negative selection	1849044
5508341	5508364	11	-	26627737	HCT116	viability after 8 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	-0.09824326614847469	[276]	[143,158,124]	-1	hSpCas9	negative selection	1849045
5508842	5508865	11	-	26627737	HCT116	viability after 8 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.26070845486679356	[399]	[313,289,189]	3	hSpCas9	negative selection	1849046
5509006	5509029	11	+	26627737	HCT116	viability after 8 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	-0.6908519506733717	[470]	[166,117,196]	-7	hSpCas9	negative selection	1849047
5507698	5507721	11	-	26627737	HCT116	viability after 9 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	-0.047165517990831685	[139]	[43,29]	0	hSpCas9	negative selection	1931357
5507970	5507993	11	-	26627737	HCT116	viability after 9 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.01957749533338171	[795]	[234,199]	0	hSpCas9	negative selection	1931358
5508099	5508122	11	+	26627737	HCT116	viability after 9 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.6217034733475456	[754]	[541,126]	4	hSpCas9	negative selection	1931359
5508341	5508364	11	-	26627737	HCT116	viability after 9 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.06144223767248341	[503]	[183,105]	0	hSpCas9	negative selection	1931360
5508842	5508865	11	-	26627737	HCT116	viability after 9 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	-1.0111713273490066	[864]	[189,54]	-6	hSpCas9	negative selection	1931361
5509006	5509029	11	+	26627737	HCT116	viability after 9 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	-0.2270823220850483	[1252]	[210,344]	-1	hSpCas9	negative selection	1931362
5507698	5507721	11	-	26627737	HCT116	viability after 12 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	-0.018950345847356886	[152]	[64,106,67]	0	hSpCas9	negative selection	2013672
5507970	5507993	11	-	26627737	HCT116	viability after 12 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.12470286867854191	[410]	[227,229,248]	1	hSpCas9	negative selection	2013673
5508099	5508122	11	+	26627737	HCT116	viability after 12 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	-0.2091383550725736	[685]	[392,292,241]	-2	hSpCas9	negative selection	2013674
5508341	5508364	11	-	26627737	HCT116	viability after 12 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.1737486780995252	[276]	[165,186,139]	1	hSpCas9	negative selection	2013675
5508842	5508865	11	-	26627737	HCT116	viability after 12 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.3164804060354301	[399]	[237,244,303]	3	hSpCas9	negative selection	2013676
5509006	5509029	11	+	26627737	HCT116	viability after 12 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	0.1985391729358288	[470]	[147,280,434]	2	hSpCas9	negative selection	2013677
5507698	5507721	11	-	26627737	HCT116	viability after 15 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	-0.5967446792746568	[152]	[61,72,39]	-6	hSpCas9	negative selection	2095987
5507970	5507993	11	-	26627737	HCT116	viability after 15 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.18341203794248523	[410]	[312,97,396]	1	hSpCas9	negative selection	2095988
5508099	5508122	11	+	26627737	HCT116	viability after 15 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	-0.2608702243669174	[685]	[381,209,399]	-3	hSpCas9	negative selection	2095989
5508341	5508364	11	-	26627737	HCT116	viability after 15 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.4699643000894097	[276]	[216,172,269]	4	hSpCas9	negative selection	2095990
5508842	5508865	11	-	26627737	HCT116	viability after 15 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.04301721188421559	[399]	[185,210,305]	0	hSpCas9	negative selection	2095991
5509006	5509029	11	+	26627737	HCT116	viability after 15 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	-0.22163645604209442	[470]	[301,216,185]	-2	hSpCas9	negative selection	2095992
5507698	5507721	11	-	26627737	HCT116	viability after 18 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	-0.3532223588130944	[152]	[90,58,21]	-3	hSpCas9	negative selection	2178302
5507970	5507993	11	-	26627737	HCT116	viability after 18 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	0.7391786769005428	[410]	[441,277,275]	6	hSpCas9	negative selection	2178303
5508099	5508122	11	+	26627737	HCT116	viability after 18 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.18115362128355583	[685]	[276,185,691]	1	hSpCas9	negative selection	2178304
5508341	5508364	11	-	26627737	HCT116	viability after 18 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.7586723778874255	[276]	[305,165,210]	6	hSpCas9	negative selection	2178305
5508842	5508865	11	-	26627737	HCT116	viability after 18 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.038236026026411574	[399]	[296,112,190]	0	hSpCas9	negative selection	2178306
5509006	5509029	11	+	26627737	HCT116	viability after 18 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	-0.5490728939361481	[470]	[56,177,233]	-5	hSpCas9	negative selection	2178307
5509227	5509250	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCCTCTGTCCCTACCCAGGG	UBQLN3	ENSG00000175520	0.28523342324904893	[4,3]	[4,4]	6	hSpCas9	positive selection	3030691
5509151	5509174	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGACCTAAGCTAAAGGCAGGG	UBQLN3	ENSG00000175520	0.5665593444506617	[3,3]	[3,5]	9	hSpCas9	positive selection	3030692
5509527	5509550	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGGAGAAGCCCTGCCACAGGG	UBQLN3	ENSG00000175520	0.21469747143172624	[1,1]	[2,0]	4	hSpCas9	positive selection	3030693
5508905	5508928	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTAACAACCCGGAAATTATGCGG	UBQLN3	ENSG00000175520	-0.08883578653534645	[3,3]	[3,2]	-1	hSpCas9	positive selection	3030694
5509227	5509250	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCCTCTGTCCCTACCCAGGG	UBQLN3	ENSG00000175520	-1.07828369698923	[4,4]	[2,0]	-9	hSpCas9	positive selection	3098549
5509151	5509174	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGACCTAAGCTAAAGGCAGGG	UBQLN3	ENSG00000175520	-0.37107358613844166	[3,3]	[2,0]	-5	hSpCas9	positive selection	3098550
5509527	5509550	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGGAGAAGCCCTGCCACAGGG	UBQLN3	ENSG00000175520	0.20433449851313723	[1,1]	[1,0]	3	hSpCas9	positive selection	3098551
5508905	5508928	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTAACAACCCGGAAATTATGCGG	UBQLN3	ENSG00000175520	0.2548875436742828	[3,3]	[3,2]	4	hSpCas9	positive selection	3098552
5507623	5507646		-	24336571	A375	resistance to PLX after 7 days	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.030257379230693965	[9,12]	[10,11]	-1	hSpCas9	positive selection	3154067
5507626	5507649		+	24336571	A375	resistance to PLX after 7 days	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	-0.28551038732914136	[13,13]	[10,10]	-8	hSpCas9	positive selection	3154068
5507623	5507646		-	24336571	A375	resistance to PLX after 14 days	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.00671995994985064	[8,8]	[3,3]	0	hSpCas9	positive selection	3211860
5507626	5507649		+	24336571	A375	resistance to PLX after 14 days	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	-0.39305286769623016	[9,6]	[2,2]	-5	hSpCas9	positive selection	3211861
5507623	5507646		-	24336571	A375	viability after 7 days	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.4311500365812343	[8]	[9,12]	6	hSpCas9	negative selection	3269653
5507626	5507649		+	24336571	A375	viability after 7 days	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.6136694936011524	[8]	[13,13]	8	hSpCas9	negative selection	3269654
5507623	5507646		-	24336571	A375	viability after 14 days	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.11769635920085181	[8]	[8,8]	1	hSpCas9	negative selection	3327446
5507626	5507649		+	24336571	A375	viability after 14 days	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	-0.0641705455973472	[8]	[9,6]	0	hSpCas9	negative selection	3327447
5509393	5509416	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	-0.20210540719146217	[175,175]	[0,0]	-1	hSpCas9	positive selection	3400121
5509143	5509166	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.514163258054763	[436,436]	[1,1]	-3	hSpCas9	positive selection	3400122
5508748	5508771	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-1.6615370258287594	[483,483]	[0,0]	-9	hSpCas9	positive selection	3400123
5509227	5509250	11	-	26780180	HT29	viability (Avana library 4 designs)	GCTGCCTCTGTCCCTACCCAGGG	UBQLN3	ENSG00000175520	1.06380878520566	[]	[]	4	hSpCas9	negative selection	3469628
5509150	5509173	11	+	26780180	HT29	viability (Avana library 4 designs)	GGAGACCTAAGCTAAAGGCAGGG	UBQLN3	ENSG00000175520	2.26818745668784	[]	[]	7	hSpCas9	negative selection	3469629
5509527	5509550	11	-	26780180	HT29	viability (Avana library 4 designs)	GGTGGAGAAGCCCTGCCACAGGG	UBQLN3	ENSG00000175520	0.880515888524985	[]	[]	3	hSpCas9	negative selection	3469630
5508905	5508928	11	-	26780180	HT29	viability (Avana library 4 designs)	TTAACAACCCGGAAATTATGCGG	UBQLN3	ENSG00000175520	0.25066146030225	[]	[]	0	hSpCas9	negative selection	3469631
5509150	5509173	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGACCTAAGCTAAAGGCAGGG	UBQLN3	ENSG00000175520	1.81115591638743	[]	[]	2	hSpCas9	negative selection	3574951
5509227	5509250	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCCTCTGTCCCTACCCAGGG	UBQLN3	ENSG00000175520	4.09289162814346	[]	[]	6	hSpCas9	negative selection	3574952
5508905	5508928	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTAACAACCCGGAAATTATGCGG	UBQLN3	ENSG00000175520	-3.85885839762734	[]	[]	-4	hSpCas9	negative selection	3574953
5509527	5509550	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGGAGAAGCCCTGCCACAGGG	UBQLN3	ENSG00000175520	5.03077268135971	[]	[]	8	hSpCas9	negative selection	3574954
5508735	5508758	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGTCCAGGAGCAGTTTGGCGG	UBQLN3	ENSG00000175520	3.51766419901906	[]	[]	5	hSpCas9	negative selection	3574955
5509276	5509299	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	4.25661813263014	[]	[]	7	hSpCas9	negative selection	3574956
5509150	5509173	11	+	26780180	A375	viability (Avana lentiGuide)	GGAGACCTAAGCTAAAGGCAGGG	UBQLN3	ENSG00000175520	-1.78379901246398	[]	[]	-3	hSpCas9	negative selection	3683610
5509227	5509250	11	-	26780180	A375	viability (Avana lentiGuide)	GCTGCCTCTGTCCCTACCCAGGG	UBQLN3	ENSG00000175520	3.35849681998136	[]	[]	3	hSpCas9	negative selection	3683611
5508905	5508928	11	-	26780180	A375	viability (Avana lentiGuide)	TTAACAACCCGGAAATTATGCGG	UBQLN3	ENSG00000175520	-3.48723241557358	[]	[]	-6	hSpCas9	negative selection	3683612
5509527	5509550	11	-	26780180	A375	viability (Avana lentiGuide)	GGTGGAGAAGCCCTGCCACAGGG	UBQLN3	ENSG00000175520	-0.0340567499170894	[]	[]	0	hSpCas9	negative selection	3683613
5508735	5508758	11	-	26780180	A375	viability (Avana lentiGuide)	GCAGTCCAGGAGCAGTTTGGCGG	UBQLN3	ENSG00000175520	3.15560409896032	[]	[]	3	hSpCas9	negative selection	3683614
5509276	5509299	11	+	26780180	A375	viability (Avana lentiGuide)	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	-3.67211802223585	[]	[]	-6	hSpCas9	negative selection	3683615
5509150	5509173	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGACCTAAGCTAAAGGCAGGG	UBQLN3	ENSG00000175520	-0.12261999543412974	[5]	[4,4]	-2	hSpCas9	positive selection	3792217
5509227	5509250	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCCTCTGTCCCTACCCAGGG	UBQLN3	ENSG00000175520	0.212562409485401	[4]	[5,4]	6	hSpCas9	positive selection	3792218
5508905	5508928	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAACAACCCGGAAATTATGCGG	UBQLN3	ENSG00000175520	-0.6041297829413472	[6]	[4,2]	-7	hSpCas9	positive selection	3792219
5509527	5509550	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGGAGAAGCCCTGCCACAGGG	UBQLN3	ENSG00000175520	0.5125692201831317	[4]	[5,6]	9	hSpCas9	positive selection	3792220
5508735	5508758	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGTCCAGGAGCAGTTTGGCGG	UBQLN3	ENSG00000175520	0.38791917847871105	[4]	[5,5]	9	hSpCas9	positive selection	3792221
5509276	5509299	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	0.3024393435754369	[4]	[5,5]	8	hSpCas9	positive selection	3792222
5509150	5509173	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGACCTAAGCTAAAGGCAGGG	UBQLN3	ENSG00000175520	0.0053837296957392755	[4]	[5,2]	0	hSpCas9	positive selection	3900824
5509227	5509250	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCCTCTGTCCCTACCCAGGG	UBQLN3	ENSG00000175520	-0.3097147123217671	[5]	[4,2]	-4	hSpCas9	positive selection	3900825
5508905	5508928	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAACAACCCGGAAATTATGCGG	UBQLN3	ENSG00000175520	0.1878634545936913	[5]	[5,5]	4	hSpCas9	positive selection	3900826
5509527	5509550	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGGAGAAGCCCTGCCACAGGG	UBQLN3	ENSG00000175520	-0.3672314619550019	[3]	[1,2]	-5	hSpCas9	positive selection	3900827
5508735	5508758	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGTCCAGGAGCAGTTTGGCGG	UBQLN3	ENSG00000175520	-0.02801718454978499	[5]	[3,5]	0	hSpCas9	positive selection	3900828
5509276	5509299	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	0.35046160571765855	[5]	[6,4]	9	hSpCas9	positive selection	3900829
5509393	5509416	11	-	26780180	A375	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.981617931492757	[]	[]	4	hSpCas9	negative selection	4009930
5507623	5507646	11	-	26780180	A375	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.144806374569051	[]	[]	0	hSpCas9	negative selection	4009931
5508748	5508771	11	-	26780180	A375	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	1.09472236134866	[]	[]	5	hSpCas9	negative selection	4009932
5507626	5507649	11	+	26780180	A375	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.123659142667282	[]	[]	0	hSpCas9	negative selection	4009933
5507968	5507991	11	+	26780180	A375	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	1.13897895011473	[]	[]	6	hSpCas9	negative selection	4009934
5509143	5509166	11	-	26780180	A375	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	1.42569542633307	[]	[]	7	hSpCas9	negative selection	4009935
5509393	5509416	11	-	26780180	HT29	viability (GeCKOv2 library)	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	1.09977763462913	[]	[]	5	hSpCas9	negative selection	4117896
5507623	5507646	11	-	26780180	HT29	viability (GeCKOv2 library)	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.38330450021915	[]	[]	1	hSpCas9	negative selection	4117897
5508748	5508771	11	-	26780180	HT29	viability (GeCKOv2 library)	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	1.15240433555877	[]	[]	5	hSpCas9	negative selection	4117898
5507626	5507649	11	+	26780180	HT29	viability (GeCKOv2 library)	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	-0.0856007050920972	[]	[]	-2	hSpCas9	negative selection	4117899
5507968	5507991	11	+	26780180	HT29	viability (GeCKOv2 library)	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.765747871158954	[]	[]	3	hSpCas9	negative selection	4117900
5509143	5509166	11	-	26780180	HT29	viability (GeCKOv2 library)	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	1.50490995145603	[]	[]	7	hSpCas9	negative selection	4117901
5507623	5507646	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.009694234712006672	[3]	[1,1]	0	hSpCas9	positive selection	4180740
5507626	5507649	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	-0.15163828621307926	[3]	[2,1]	-4	hSpCas9	positive selection	4180741
5507623	5507646	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.4458605794969438	[2]	[2,2,1,0]	3	hSpCas9	positive selection	4244762
5507626	5507649	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	1.1440442359485337	[3]	[3,0,0,5]	8	hSpCas9	positive selection	4244763
5507623	5507646	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.3819547324244057	[0]	[0,0]	7	hSpCas9	positive selection	4306356
5507626	5507649	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.46899416279311595	[3]	[4,4]	8	hSpCas9	positive selection	4306357
5507968	5507991	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.21317246678809365	[2]	[2,1]	4	hSpCas9	positive selection	4306358
5509393	5509416	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.04825291156492223	[3]	[3,1]	1	hSpCas9	positive selection	4370605
5509143	5509166	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	0.13621712848619022	[4]	[3,3]	2	hSpCas9	positive selection	4370606
5508748	5508771	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.12375298630909565	[4]	[4,2]	2	hSpCas9	positive selection	4370607
5508748	5508770	11	+	27760321	OCIAML3	viability	CCTGGACTGCGTTAAGCATTGG	UBQLN3	ENSG00000175520	-0.6445278916817887	[392,338]	[123,258]	-6	hSpCas9	negative selection	4451956
5508865	5508887	11	-	27760321	OCIAML3	viability	CGTAACCCTGCCATGATGCAGG	UBQLN3	ENSG00000175520	0.12056442319960747	[832,739]	[681,648]	1	hSpCas9	negative selection	4451957
5508988	5509010	11	-	27760321	OCIAML3	viability	ACAGGCCTAGTACGCCAGCTGG	UBQLN3	ENSG00000175520	-0.018779354583946917	[605,547]	[395,508]	0	hSpCas9	negative selection	4451958
5509150	5509172	11	+	27760321	OCIAML3	viability	GGAGACCTAAGCTAAAGGCAGG	UBQLN3	ENSG00000175520	-0.3640914931990579	[403,330]	[170,288]	-4	hSpCas9	negative selection	4451959
5509370	5509392	11	+	27760321	OCIAML3	viability	TAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.019713207448464554	[519,416]	[321,430]	0	hSpCas9	negative selection	4451960
5508748	5508770	11	+	27760321	OCIAML2	viability	CCTGGACTGCGTTAAGCATTGG	UBQLN3	ENSG00000175520	0.2530461938895513	[392,338]	[287,435]	3	hSpCas9	negative selection	4535419
5508865	5508887	11	-	27760321	OCIAML2	viability	CGTAACCCTGCCATGATGCAGG	UBQLN3	ENSG00000175520	-0.08331213905996182	[832,739]	[552,660]	-1	hSpCas9	negative selection	4535420
5508988	5509010	11	-	27760321	OCIAML2	viability	ACAGGCCTAGTACGCCAGCTGG	UBQLN3	ENSG00000175520	-0.09270470939682263	[605,547]	[385,504]	-1	hSpCas9	negative selection	4535421
5509150	5509172	11	+	27760321	OCIAML2	viability	GGAGACCTAAGCTAAAGGCAGG	UBQLN3	ENSG00000175520	0.05502744859062153	[403,330]	[214,428]	0	hSpCas9	negative selection	4535422
5509370	5509392	11	+	27760321	OCIAML2	viability	TAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.03551672313853897	[519,416]	[333,454]	0	hSpCas9	negative selection	4535423
5508748	5508770	11	+	27760321	MV411	viability	CCTGGACTGCGTTAAGCATTGG	UBQLN3	ENSG00000175520	1.0869216796068544	[392,338]	[780,106]	7	hSpCas9	negative selection	4618882
5508865	5508887	11	-	27760321	MV411	viability	CGTAACCCTGCCATGATGCAGG	UBQLN3	ENSG00000175520	1.1600235927455458	[832,739]	[1362,849]	8	hSpCas9	negative selection	4618883
5508988	5509010	11	-	27760321	MV411	viability	ACAGGCCTAGTACGCCAGCTGG	UBQLN3	ENSG00000175520	0.17667538579949527	[605,547]	[194,782]	1	hSpCas9	negative selection	4618884
5509150	5509172	11	+	27760321	MV411	viability	GGAGACCTAAGCTAAAGGCAGG	UBQLN3	ENSG00000175520	-0.6921516435595871	[403,330]	[110,206]	-5	hSpCas9	negative selection	4618885
5509370	5509392	11	+	27760321	MV411	viability	TAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.166793455166229	[519,416]	[179,592]	1	hSpCas9	negative selection	4618886
5508748	5508770	11	+	27760321	HL60	viability	CCTGGACTGCGTTAAGCATTGG	UBQLN3	ENSG00000175520	2.378301457265852	[392,338]	[1322,1790]	9	hSpCas9	negative selection	4702345
5508865	5508887	11	-	27760321	HL60	viability	CGTAACCCTGCCATGATGCAGG	UBQLN3	ENSG00000175520	-0.3352614755784523	[832,739]	[539,474]	-4	hSpCas9	negative selection	4702346
5508988	5509010	11	-	27760321	HL60	viability	ACAGGCCTAGTACGCCAGCTGG	UBQLN3	ENSG00000175520	0.26842859498746463	[605,547]	[475,663]	3	hSpCas9	negative selection	4702347
5509150	5509172	11	+	27760321	HL60	viability	GGAGACCTAAGCTAAAGGCAGG	UBQLN3	ENSG00000175520	0.6632392304241703	[403,330]	[525,416]	7	hSpCas9	negative selection	4702348
5509370	5509392	11	+	27760321	HL60	viability	TAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.2587655404905931	[519,416]	[463,445]	3	hSpCas9	negative selection	4702349
5508748	5508770	11	+	27760321	HT1080	viability	CCTGGACTGCGTTAAGCATTGG	UBQLN3	ENSG00000175520	1.2636038761837693	[338,264]	[317,256]	7	hSpCas9	negative selection	4785808
5508865	5508887	11	-	27760321	HT1080	viability	CGTAACCCTGCCATGATGCAGG	UBQLN3	ENSG00000175520	0.2637929061575416	[739,577]	[129,517]	1	hSpCas9	negative selection	4785809
5508988	5509010	11	-	27760321	HT1080	viability	ACAGGCCTAGTACGCCAGCTGG	UBQLN3	ENSG00000175520	1.2589781325455107	[547,427]	[544,377]	6	hSpCas9	negative selection	4785810
5509150	5509172	11	+	27760321	HT1080	viability	GGAGACCTAAGCTAAAGGCAGG	UBQLN3	ENSG00000175520	1.448506174809468	[330,257]	[386,246]	7	hSpCas9	negative selection	4785811
5509370	5509392	11	+	27760321	HT1080	viability	TAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	-1.1081108145547307	[416,325]	[50,87]	-4	hSpCas9	negative selection	4785812
5508748	5508770	11	+	27760321	HT29	viability after 7 days	CCTGGACTGCGTTAAGCATTGG	UBQLN3	ENSG00000175520	0.16164401966649794	[338,264]	[457,545,305]	2	hSpCas9	negative selection	4869271
5508865	5508887	11	-	27760321	HT29	viability after 7 days	CGTAACCCTGCCATGATGCAGG	UBQLN3	ENSG00000175520	0.20129749080000725	[739,577]	[1064,731,1131]	3	hSpCas9	negative selection	4869272
5508988	5509010	11	-	27760321	HT29	viability after 7 days	ACAGGCCTAGTACGCCAGCTGG	UBQLN3	ENSG00000175520	0.2531464280664606	[547,427]	[706,701,824]	4	hSpCas9	negative selection	4869273
5509150	5509172	11	+	27760321	HT29	viability after 7 days	GGAGACCTAAGCTAAAGGCAGG	UBQLN3	ENSG00000175520	-0.11271196685879259	[330,257]	[284,383,370]	-2	hSpCas9	negative selection	4869274
5509370	5509392	11	+	27760321	HT29	viability after 7 days	TAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.008991184101294132	[416,325]	[415,499,514]	0	hSpCas9	negative selection	4869275
5508748	5508770	11	+	27760321	HT29	viability after 25 days	CCTGGACTGCGTTAAGCATTGG	UBQLN3	ENSG00000175520	0.8064072877394804	[338,264]	[747,508,536]	8	hSpCas9	negative selection	4952734
5508865	5508887	11	-	27760321	HT29	viability after 25 days	CGTAACCCTGCCATGATGCAGG	UBQLN3	ENSG00000175520	0.35124806464147496	[739,577]	[925,970,988]	4	hSpCas9	negative selection	4952735
5508988	5509010	11	-	27760321	HT29	viability after 25 days	ACAGGCCTAGTACGCCAGCTGG	UBQLN3	ENSG00000175520	0.5492511790053911	[547,427]	[889,688,868]	6	hSpCas9	negative selection	4952736
5509150	5509172	11	+	27760321	HT29	viability after 25 days	GGAGACCTAAGCTAAAGGCAGG	UBQLN3	ENSG00000175520	0.4152095295356694	[330,257]	[293,520,550]	4	hSpCas9	negative selection	4952737
5509370	5509392	11	+	27760321	HT29	viability after 25 days	TAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.006394605115101502	[416,325]	[376,408,503]	0	hSpCas9	negative selection	4952738
5508748	5508770	11	+	27760321	HT29	viability after 22 days	CCTGGACTGCGTTAAGCATTGG	UBQLN3	ENSG00000175520	0.5628380565621571	[338,264]	[400,674,473]	6	hSpCas9	negative selection	5036197
5508865	5508887	11	-	27760321	HT29	viability after 22 days	CGTAACCCTGCCATGATGCAGG	UBQLN3	ENSG00000175520	0.21323194726738393	[739,577]	[983,666,996]	2	hSpCas9	negative selection	5036198
5508988	5509010	11	-	27760321	HT29	viability after 22 days	ACAGGCCTAGTACGCCAGCTGG	UBQLN3	ENSG00000175520	0.49148675407663756	[547,427]	[741,622,1017]	5	hSpCas9	negative selection	5036199
5509150	5509172	11	+	27760321	HT29	viability after 22 days	GGAGACCTAAGCTAAAGGCAGG	UBQLN3	ENSG00000175520	0.5725522574370314	[330,257]	[452,584,481]	6	hSpCas9	negative selection	5036200
5509370	5509392	11	+	27760321	HT29	viability after 22 days	TAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.21779082561894508	[416,325]	[576,357,561]	2	hSpCas9	negative selection	5036201
5508748	5508770	11	+	27760321	HT29	viability after 19 days	CCTGGACTGCGTTAAGCATTGG	UBQLN3	ENSG00000175520	0.20834490305065187	[338,264]	[527,430,256]	2	hSpCas9	negative selection	5119660
5508865	5508887	11	-	27760321	HT29	viability after 19 days	CGTAACCCTGCCATGATGCAGG	UBQLN3	ENSG00000175520	0.24967070598398278	[739,577]	[825,812,1035]	2	hSpCas9	negative selection	5119661
5508988	5509010	11	-	27760321	HT29	viability after 19 days	ACAGGCCTAGTACGCCAGCTGG	UBQLN3	ENSG00000175520	0.4828274815458483	[547,427]	[994,534,829]	5	hSpCas9	negative selection	5119662
5509150	5509172	11	+	27760321	HT29	viability after 19 days	GGAGACCTAAGCTAAAGGCAGG	UBQLN3	ENSG00000175520	0.9353235228140255	[330,257]	[1010,633,336]	8	hSpCas9	negative selection	5119663
5509370	5509392	11	+	27760321	HT29	viability after 19 days	TAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.5357462175079768	[416,325]	[478,945,415]	5	hSpCas9	negative selection	5119664
5508748	5508770	11	+	27760321	HT29	viability after 16 days	CCTGGACTGCGTTAAGCATTGG	UBQLN3	ENSG00000175520	0.38770680493551757	[338,264]	[477,426,424]	4	hSpCas9	negative selection	5203123
5508865	5508887	11	-	27760321	HT29	viability after 16 days	CGTAACCCTGCCATGATGCAGG	UBQLN3	ENSG00000175520	0.4248006537239005	[739,577]	[971,1008,985]	5	hSpCas9	negative selection	5203124
5508988	5509010	11	-	27760321	HT29	viability after 16 days	ACAGGCCTAGTACGCCAGCTGG	UBQLN3	ENSG00000175520	0.28817958936048294	[547,427]	[1168,417,466]	3	hSpCas9	negative selection	5203125
5509150	5509172	11	+	27760321	HT29	viability after 16 days	GGAGACCTAAGCTAAAGGCAGG	UBQLN3	ENSG00000175520	-0.45851803699502386	[330,257]	[266,270,182]	-5	hSpCas9	negative selection	5203126
5509370	5509392	11	+	27760321	HT29	viability after 16 days	TAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.20333879165752478	[416,325]	[416,665,341]	2	hSpCas9	negative selection	5203127
5508748	5508770	11	+	27760321	HT29	viability after 13 days	CCTGGACTGCGTTAAGCATTGG	UBQLN3	ENSG00000175520	0.2373507642709809	[338,264]	[562,386,295]	3	hSpCas9	negative selection	5286586
5508865	5508887	11	-	27760321	HT29	viability after 13 days	CGTAACCCTGCCATGATGCAGG	UBQLN3	ENSG00000175520	0.22622344888839485	[739,577]	[1039,1011,645]	3	hSpCas9	negative selection	5286587
5508988	5509010	11	-	27760321	HT29	viability after 13 days	ACAGGCCTAGTACGCCAGCTGG	UBQLN3	ENSG00000175520	0.6784346375766812	[547,427]	[1095,687,931]	8	hSpCas9	negative selection	5286588
5509150	5509172	11	+	27760321	HT29	viability after 13 days	GGAGACCTAAGCTAAAGGCAGG	UBQLN3	ENSG00000175520	-0.06305821276422718	[330,257]	[473,236,272]	0	hSpCas9	negative selection	5286589
5509370	5509392	11	+	27760321	HT29	viability after 13 days	TAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.1609339769017381	[416,325]	[668,325,451]	2	hSpCas9	negative selection	5286590
5508748	5508770	11	+	27760321	HT29	viability after 10 days	CCTGGACTGCGTTAAGCATTGG	UBQLN3	ENSG00000175520	0.5443947829632836	[338,264]	[605,668,381]	7	hSpCas9	negative selection	5370049
5508865	5508887	11	-	27760321	HT29	viability after 10 days	CGTAACCCTGCCATGATGCAGG	UBQLN3	ENSG00000175520	0.19991314149492168	[739,577]	[960,932,940]	2	hSpCas9	negative selection	5370050
5508988	5509010	11	-	27760321	HT29	viability after 10 days	ACAGGCCTAGTACGCCAGCTGG	UBQLN3	ENSG00000175520	0.5513363846723196	[547,427]	[1015,724,931]	7	hSpCas9	negative selection	5370051
5509150	5509172	11	+	27760321	HT29	viability after 10 days	GGAGACCTAAGCTAAAGGCAGG	UBQLN3	ENSG00000175520	-0.2474156676776254	[330,257]	[231,381,316]	-3	hSpCas9	negative selection	5370052
5509370	5509392	11	+	27760321	HT29	viability after 10 days	TAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	-0.22559084176537753	[416,325]	[241,422,522]	-3	hSpCas9	negative selection	5370053
5508748	5508770	11	+	27760321	MOLM13	viability	CCTGGACTGCGTTAAGCATTGG	UBQLN3	ENSG00000175520	0.8941506001301411	[392,338]	[278,470]	6	hSpCas9	negative selection	5453512
5508865	5508887	11	-	27760321	MOLM13	viability	CGTAACCCTGCCATGATGCAGG	UBQLN3	ENSG00000175520	0.25851381073508484	[832,739]	[704,380]	1	hSpCas9	negative selection	5453513
5508988	5509010	11	-	27760321	MOLM13	viability	ACAGGCCTAGTACGCCAGCTGG	UBQLN3	ENSG00000175520	0.25632327248540887	[605,547]	[495,296]	1	hSpCas9	negative selection	5453514
5509150	5509172	11	+	27760321	MOLM13	viability	GGAGACCTAAGCTAAAGGCAGG	UBQLN3	ENSG00000175520	-0.8812876904248272	[403,330]	[131,94]	-5	hSpCas9	negative selection	5453515
5509370	5509392	11	+	27760321	MOLM13	viability	TAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	1.0730026893740865	[519,416]	[829,316]	7	hSpCas9	negative selection	5453516
5509921	5509944	11	-	27661255	K562	viability	GTGGCTGTGTAGCAAGATGAGGG	UBQLN3	ENSG00000175520	0.2000954395626504	[780,955]	[907,696]	7	dCas9-KRAB	negative selection	5521249
5507623	5507646	11	-	27260156	BXPC3	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-1.215048863871412	[19]	[2,13,4,14]	-9	hSpCas9	negative selection	5578816
5507626	5507649	11	+	27260156	BXPC3	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.22877953505799709	[954]	[1026,1169,1195,1312]	5	hSpCas9	negative selection	5578817
5507968	5507991	11	+	27260156	BXPC3	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.5962559170765167	[248]	[563,321,274,393]	9	hSpCas9	negative selection	5578818
5509393	5509416	11	-	27260156	BXPC3	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	-0.055956288664763695	[520]	[408,429,674,609]	-1	hSpCas9	negative selection	5643065
5509143	5509166	11	-	27260156	BXPC3	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.0019502759031138073	[991]	[1001,798,1089,1295]	0	hSpCas9	negative selection	5643066
5508748	5508771	11	-	27260156	BXPC3	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.04538067180017169	[1206]	[1158,1062,1250,1455]	-1	hSpCas9	negative selection	5643067
5507623	5507646	11	-	27260156	A673	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.27762509601847807	[19]	[17,30,21,44]	6	hSpCas9	negative selection	5700067
5507626	5507649	11	+	27260156	A673	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.20661229146190307	[954]	[1362,1205,1423,1302]	5	hSpCas9	negative selection	5700068
5507968	5507991	11	+	27260156	A673	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.6743260934754236	[248]	[534,451,525,396]	9	hSpCas9	negative selection	5700069
5509393	5509416	11	-	27260156	A673	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	-0.05666715140241721	[520]	[599,575,568,663]	-1	hSpCas9	negative selection	5764316
5509143	5509166	11	-	27260156	A673	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.14229581631279564	[991]	[1355,950,908,1138]	-4	hSpCas9	negative selection	5764317
5508748	5508771	11	-	27260156	A673	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.13854101331044744	[1206]	[1691,1316,1715,1674]	3	hSpCas9	negative selection	5764318
5507623	5507646	11	-	27260156	A375	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-1.3787738127025033	[19]	[0,7,1,22]	-9	hSpCas9	negative selection	5821318
5507626	5507649	11	+	27260156	A375	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.5191867899734801	[954]	[1420,1920,1420,1660]	7	hSpCas9	negative selection	5821319
5507968	5507991	11	+	27260156	A375	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.6422772381576105	[248]	[351,636,315,524]	8	hSpCas9	negative selection	5821320
5509393	5509416	11	-	27260156	A375	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.28609771821101193	[520]	[591,1013,784,624]	4	hSpCas9	negative selection	5885567
5509143	5509166	11	-	27260156	A375	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	0.1159922822785493	[991]	[1133,1549,1092,1277]	1	hSpCas9	negative selection	5885568
5508748	5508771	11	-	27260156	A375	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.08769231429771396	[1206]	[1365,2143,1395,1204]	1	hSpCas9	negative selection	5885569
5507623	5507646	11	-	27260156	COLO741	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.3949045327097682	[19]	[13,26,16]	-7	hSpCas9	negative selection	5942569
5507626	5507649	11	+	27260156	COLO741	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	-0.010912796509559008	[954]	[1338,1328,989]	0	hSpCas9	negative selection	5942570
5507968	5507991	11	+	27260156	COLO741	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.7460931874360633	[248]	[584,444,570]	9	hSpCas9	negative selection	5942571
5509393	5509416	11	-	27260156	COLO741	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.10157927179602846	[520]	[753,739,654]	2	hSpCas9	negative selection	6006818
5509143	5509166	11	-	27260156	COLO741	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.2521677668016693	[991]	[1124,1168,912]	-5	hSpCas9	negative selection	6006819
5508748	5508771	11	-	27260156	COLO741	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.07541820928534215	[1206]	[1593,1515,1300]	-2	hSpCas9	negative selection	6006820
5507623	5507646	11	-	27260156	CAL120	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.18012362719573094	[19]	[2,35,23]	-3	hSpCas9	negative selection	6063820
5507626	5507649	11	+	27260156	CAL120	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.44053535553672374	[954]	[1911,1599,1374]	6	hSpCas9	negative selection	6063821
5507968	5507991	11	+	27260156	CAL120	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.7698472018546215	[248]	[431,650,487]	9	hSpCas9	negative selection	6063822
5509393	5509416	11	-	27260156	CAL120	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.4775160038689854	[520]	[932,805,971]	7	hSpCas9	negative selection	6128069
5509143	5509166	11	-	27260156	CAL120	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	0.1624208558171898	[991]	[2031,1225,990]	2	hSpCas9	negative selection	6128070
5508748	5508771	11	-	27260156	CAL120	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.0333196871237087	[1206]	[2031,1281,1373]	0	hSpCas9	negative selection	6128071
5507623	5507646	11	-	27260156	CADOES1	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.8330605862234668	[19]	[12,6,4,16]	-9	hSpCas9	negative selection	6185071
5507626	5507649	11	+	27260156	CADOES1	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.264583893728507	[954]	[1309,1058,1044,844]	4	hSpCas9	negative selection	6185072
5507968	5507991	11	+	27260156	CADOES1	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.6356543766960616	[248]	[294,386,458,295]	9	hSpCas9	negative selection	6185073
5509393	5509416	11	-	27260156	CADOES1	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.056155047020364196	[520]	[451,529,563,467]	1	hSpCas9	negative selection	6249320
5509143	5509166	11	-	27260156	CADOES1	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.0574781459700795	[991]	[1013,806,808,916]	-1	hSpCas9	negative selection	6249321
5508748	5508771	11	-	27260156	CADOES1	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.17295170007261618	[1206]	[1302,1112,1501,1138]	3	hSpCas9	negative selection	6249322
5507623	5507646	11	-	27260156	EWS502	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.967280306596646	[19]	[24,42,68,29]	9	hSpCas9	negative selection	6306322
5507626	5507649	11	+	27260156	EWS502	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.21093580663438583	[954]	[1144,1157,946,1448]	3	hSpCas9	negative selection	6306323
5507968	5507991	11	+	27260156	EWS502	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.8124498133119592	[248]	[388,477,452,544]	9	hSpCas9	negative selection	6306324
5509393	5509416	11	-	27260156	EWS502	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.20027766238044506	[520]	[564,685,624,665]	3	hSpCas9	negative selection	6370571
5509143	5509166	11	-	27260156	EWS502	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.20710233101595732	[991]	[915,857,943,921]	-4	hSpCas9	negative selection	6370572
5508748	5508771	11	-	27260156	EWS502	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.08885855460367242	[1206]	[1253,1497,1328,1358]	1	hSpCas9	negative selection	6370573
5507623	5507646	11	-	27260156	EW8	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.783993604377005	[19]	[7,4,11,11]	-8	hSpCas9	negative selection	6427573
5507626	5507649	11	+	27260156	EW8	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.1936688140073204	[954]	[898,942,788,924]	3	hSpCas9	negative selection	6427574
5507968	5507991	11	+	27260156	EW8	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.7781921499540464	[248]	[393,341,217,455]	9	hSpCas9	negative selection	6427575
5509393	5509416	11	-	27260156	EW8	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.18859553524849146	[520]	[505,369,572,460]	3	hSpCas9	negative selection	6491822
5509143	5509166	11	-	27260156	EW8	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.03144577370033064	[991]	[1034,690,746,704]	0	hSpCas9	negative selection	6491823
5508748	5508771	11	-	27260156	EW8	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.10027784297355025	[1206]	[1279,878,934,1140]	1	hSpCas9	negative selection	6491824
5507623	5507646	11	-	27260156	CORL105	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.26046235896165104	[19]	[23,33,40,14]	5	hSpCas9	negative selection	6548824
5507626	5507649	11	+	27260156	CORL105	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.4830751000373612	[954]	[1332,1548,1934,1483]	8	hSpCas9	negative selection	6548825
5507968	5507991	11	+	27260156	CORL105	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.937892672775155	[248]	[515,464,774,511]	9	hSpCas9	negative selection	6548826
5509393	5509416	11	-	27260156	CORL105	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.14264208295328226	[520]	[574,699,786,644]	2	hSpCas9	negative selection	6613073
5509143	5509166	11	-	27260156	CORL105	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	0.02611289047269838	[991]	[1072,1098,1483,1118]	0	hSpCas9	negative selection	6613074
5508748	5508771	11	-	27260156	CORL105	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.09210240445748208	[1206]	[1256,1379,1240,1406]	-2	hSpCas9	negative selection	6613075
5507623	5507646	11	-	27260156	HS294T	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.8493375429999634	[19]	[1,8,2,2]	-8	hSpCas9	negative selection	6670075
5507626	5507649	11	+	27260156	HS294T	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.33016762595400295	[954]	[312,487,524,558]	4	hSpCas9	negative selection	6670076
5507968	5507991	11	+	27260156	HS294T	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	1.2230526440874274	[248]	[192,249,159,311]	9	hSpCas9	negative selection	6670077
5509393	5509416	11	-	27260156	HS294T	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	-0.3438270240083132	[520]	[175,126,190,135]	-5	hSpCas9	negative selection	6734324
5509143	5509166	11	-	27260156	HS294T	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	0.3290325914215779	[991]	[793,366,351,366]	4	hSpCas9	negative selection	6734325
5508748	5508771	11	-	27260156	HS294T	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.048007484954031066	[1206]	[664,411,407,416]	0	hSpCas9	negative selection	6734326
5507623	5507646	11	-	27260156	HCC44	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.6519010133729459	[19]	[95,9,0,37]	9	hSpCas9	negative selection	6791326
5507626	5507649	11	+	27260156	HCC44	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.39200721429969754	[954]	[1487,933,1915,1478]	6	hSpCas9	negative selection	6791327
5507968	5507991	11	+	27260156	HCC44	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.5538353786708314	[248]	[492,434,379,342]	8	hSpCas9	negative selection	6791328
5509393	5509416	11	-	27260156	HCC44	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.06696213252800343	[520]	[923,312,630,667]	1	hSpCas9	negative selection	6855575
5509143	5509166	11	-	27260156	HCC44	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	0.29901638464409297	[991]	[1417,1250,1442,1428]	5	hSpCas9	negative selection	6855576
5508748	5508771	11	-	27260156	HCC44	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.013117955517564672	[1206]	[1514,947,2011,1118]	0	hSpCas9	negative selection	6855577
5507623	5507646	11	-	27260156	G402	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.6096731899564558	[19]	[43,3,18,0]	-6	hSpCas9	negative selection	6912577
5507626	5507649	11	+	27260156	G402	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.18991916335578196	[954]	[1318,1806,1155,1068]	2	hSpCas9	negative selection	6912578
5507968	5507991	11	+	27260156	G402	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.7702956601911548	[248]	[868,294,541,407]	8	hSpCas9	negative selection	6912579
5509393	5509416	11	-	27260156	G402	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.7597370488697346	[520]	[1031,1430,826,1027]	8	hSpCas9	negative selection	6976826
5509143	5509166	11	-	27260156	G402	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	0.3857877222794359	[991]	[2334,1624,1158,1324]	5	hSpCas9	negative selection	6976827
5508748	5508771	11	-	27260156	G402	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.04575922422309486	[1206]	[1998,1933,1408,858]	0	hSpCas9	negative selection	6976828
5507623	5507646	11	-	27260156	L33	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.5785723919139025	[19]	[16,3,14,2]	-8	hSpCas9	negative selection	7033828
5507626	5507649	11	+	27260156	L33	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.42339711705841276	[954]	[1498,489,790,1164]	8	hSpCas9	negative selection	7033829
5507968	5507991	11	+	27260156	L33	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.9514296525834794	[248]	[464,181,326,496]	9	hSpCas9	negative selection	7033830
5509393	5509416	11	-	27260156	L33	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	-0.19902566104048816	[520]	[465,203,274,413]	-4	hSpCas9	negative selection	7098077
5509143	5509166	11	-	27260156	L33	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.21951995671644164	[991]	[979,332,572,701]	-5	hSpCas9	negative selection	7098078
5508748	5508771	11	-	27260156	L33	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.0723019155005562	[1206]	[1252,479,704,1043]	-2	hSpCas9	negative selection	7098079
5507623	5507646	11	-	27260156	K562	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-2.472187008167812	[19]	[6,0,1,2]	-9	hSpCas9	negative selection	7155079
5507626	5507649	11	+	27260156	K562	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	-0.036810095229097395	[954]	[971,903,934,539]	0	hSpCas9	negative selection	7155080
5507968	5507991	11	+	27260156	K562	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.7935409996543927	[248]	[559,226,576,194]	8	hSpCas9	negative selection	7155081
5509393	5509416	11	-	27260156	K562	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.019491922237653808	[520]	[464,513,354,532]	0	hSpCas9	negative selection	7219328
5509143	5509166	11	-	27260156	K562	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	0.07087525937501371	[991]	[740,1294,831,840]	0	hSpCas9	negative selection	7219329
5508748	5508771	11	-	27260156	K562	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.31778097494187896	[1206]	[1583,961,1271,1497]	4	hSpCas9	negative selection	7219330
5507623	5507646	11	-	27260156	HT29	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.4946305812315348	[19]	[5,20,2,35]	-7	hSpCas9	negative selection	7276330
5507626	5507649	11	+	27260156	HT29	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.42969684451290546	[954]	[1495,1905,1440,1439]	8	hSpCas9	negative selection	7276331
5507968	5507991	11	+	27260156	HT29	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.692983000796966	[248]	[562,524,371,500]	9	hSpCas9	negative selection	7276332
5509393	5509416	11	-	27260156	HT29	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.07619413266118341	[520]	[889,515,605,658]	1	hSpCas9	negative selection	7340579
5509143	5509166	11	-	27260156	HT29	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.0016477748084231525	[991]	[1479,1286,1076,1016]	0	hSpCas9	negative selection	7340580
5508748	5508771	11	-	27260156	HT29	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.13196825401827672	[1206]	[1623,1479,1628,1668]	2	hSpCas9	negative selection	7340581
5507623	5507646	11	-	27260156	MHHES1	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.2617576459244644	[19]	[10,4,42,40]	5	hSpCas9	negative selection	7397581
5507626	5507649	11	+	27260156	MHHES1	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.3060324381838979	[954]	[1603,1013,1340,1329]	5	hSpCas9	negative selection	7397582
5507968	5507991	11	+	27260156	MHHES1	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.6459313008568949	[248]	[436,598,446,308]	9	hSpCas9	negative selection	7397583
5509393	5509416	11	-	27260156	MHHES1	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.16414070913327158	[520]	[751,612,850,454]	3	hSpCas9	negative selection	7461830
5509143	5509166	11	-	27260156	MHHES1	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	0.04726592657133688	[991]	[1525,1315,1148,755]	0	hSpCas9	negative selection	7461831
5508748	5508771	11	-	27260156	MHHES1	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.15110586845230922	[1206]	[1527,1859,1544,1184]	2	hSpCas9	negative selection	7461832
5507623	5507646	11	-	27260156	MEWO	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.21938737434816158	[19]	[24,3,20]	-5	hSpCas9	negative selection	7518832
5507626	5507649	11	+	27260156	MEWO	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.27857709364659233	[954]	[1313,1014,966]	6	hSpCas9	negative selection	7518833
5507968	5507991	11	+	27260156	MEWO	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.5838953285402324	[248]	[261,462,304]	9	hSpCas9	negative selection	7518834
5509393	5509416	11	-	27260156	MEWO	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.18369273508057196	[520]	[706,437,545]	4	hSpCas9	negative selection	7583081
5509143	5509166	11	-	27260156	MEWO	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	0.011353875254545676	[991]	[1285,718,869]	0	hSpCas9	negative selection	7583082
5508748	5508771	11	-	27260156	MEWO	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.06885086253524597	[1206]	[1327,924,1025]	-1	hSpCas9	negative selection	7583083
5507623	5507646	11	-	27260156	LNCAPCLONEFGC	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.9352402799491824	[19]	[10,2,20,4]	-8	hSpCas9	negative selection	7640083
5507626	5507649	11	+	27260156	LNCAPCLONEFGC	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.22247625387730552	[954]	[707,991,1132,1228]	3	hSpCas9	negative selection	7640084
5507968	5507991	11	+	27260156	LNCAPCLONEFGC	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.7966400482334385	[248]	[353,503,389,311]	9	hSpCas9	negative selection	7640085
5509393	5509416	11	-	27260156	LNCAPCLONEFGC	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.3298626569658142	[520]	[415,517,688,771]	5	hSpCas9	negative selection	7704332
5509143	5509166	11	-	27260156	LNCAPCLONEFGC	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.036424614085103224	[991]	[866,840,904,897]	0	hSpCas9	negative selection	7704333
5508748	5508771	11	-	27260156	LNCAPCLONEFGC	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.026548687869163423	[1206]	[1108,906,1418,1077]	0	hSpCas9	negative selection	7704334
5507623	5507646	11	-	27260156	PANC0327	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-2.6204984182499613	[19]	[0,5,2,0]	-9	hSpCas9	negative selection	7761334
5507626	5507649	11	+	27260156	PANC0327	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	-0.06245567634238136	[954]	[813,837,739,853]	-1	hSpCas9	negative selection	7761335
5507968	5507991	11	+	27260156	PANC0327	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.4876771436465786	[248]	[698,149,236,206]	7	hSpCas9	negative selection	7761336
5509393	5509416	11	-	27260156	PANC0327	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	-0.3857416070252242	[520]	[396,195,505,341]	-5	hSpCas9	negative selection	7825583
5509143	5509166	11	-	27260156	PANC0327	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.024699356413377505	[991]	[868,968,547,1064]	0	hSpCas9	negative selection	7825584
5508748	5508771	11	-	27260156	PANC0327	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.19635606332272348	[1206]	[1505,713,807,789]	-3	hSpCas9	negative selection	7825585
5507623	5507646	11	-	27260156	NCIH2009	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.5203422390464967	[19]	[41,11,8]	-6	hSpCas9	negative selection	7882585
5507626	5507649	11	+	27260156	NCIH2009	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.7661942102584056	[954]	[2482,2067,2298]	9	hSpCas9	negative selection	7882586
5507968	5507991	11	+	27260156	NCIH2009	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	1.3448469837618067	[248]	[950,1091,615]	9	hSpCas9	negative selection	7882587
5509393	5509416	11	-	27260156	NCIH2009	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.09818274640963207	[520]	[920,682,761]	1	hSpCas9	negative selection	7946834
5509143	5509166	11	-	27260156	NCIH2009	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.0932819023605187	[991]	[1480,1096,1356]	-1	hSpCas9	negative selection	7946835
5508748	5508771	11	-	27260156	NCIH2009	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.04531358436925936	[1206]	[1838,1764,1333]	0	hSpCas9	negative selection	7946836
5507623	5507646	11	-	27260156	NCIH1373	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-1.9365508212129487	[19]	[1,2,13,0]	-9	hSpCas9	negative selection	8003836
5507626	5507649	11	+	27260156	NCIH1373	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.6214562416261284	[954]	[2611,1006,1488,445]	6	hSpCas9	negative selection	8003837
5507968	5507991	11	+	27260156	NCIH1373	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	1.0130457973842355	[248]	[376,730,559,139]	8	hSpCas9	negative selection	8003838
5509393	5509416	11	-	27260156	NCIH1373	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.6266563337788466	[520]	[1769,521,853,161]	6	hSpCas9	negative selection	8068085
5509143	5509166	11	-	27260156	NCIH1373	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	0.4888444135847114	[991]	[1864,1255,993,591]	5	hSpCas9	negative selection	8068086
5508748	5508771	11	-	27260156	NCIH1373	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.2732877689063058	[1206]	[1812,1241,1274,609]	2	hSpCas9	negative selection	8068087
5507623	5507646	11	-	27260156	PATU8902	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.888516600486247	[19]	[11,3,2,219]	8	hSpCas9	negative selection	8125087
5507626	5507649	11	+	27260156	PATU8902	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.2701635540526708	[954]	[1541,1751,1417,1758]	2	hSpCas9	negative selection	8125088
5507968	5507991	11	+	27260156	PATU8902	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	1.057181424406133	[248]	[867,806,434,859]	9	hSpCas9	negative selection	8125089
5509393	5509416	11	-	27260156	PATU8902	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.46178440982411206	[520]	[1175,928,803,1145]	5	hSpCas9	negative selection	8189336
5509143	5509166	11	-	27260156	PATU8902	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	0.33876048018208627	[991]	[1415,1977,1573,2098]	3	hSpCas9	negative selection	8189337
5508748	5508771	11	-	27260156	PATU8902	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.017007530906923307	[1206]	[2003,1943,1000,2062]	0	hSpCas9	negative selection	8189338
5507623	5507646	11	-	27260156	PANC1	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	1.1990056889427474	[19]	[61,55,43,3]	9	hSpCas9	negative selection	8246338
5507626	5507649	11	+	27260156	PANC1	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.23360708271404285	[954]	[1083,1020,885,873]	4	hSpCas9	negative selection	8246339
5507968	5507991	11	+	27260156	PANC1	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	1.0649451314394007	[248]	[345,771,437,316]	9	hSpCas9	negative selection	8246340
5509393	5509416	11	-	27260156	PANC1	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.15727083389773974	[520]	[499,512,541,444]	2	hSpCas9	negative selection	8310587
5509143	5509166	11	-	27260156	PANC1	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.04515166179626906	[991]	[836,1007,680,802]	0	hSpCas9	negative selection	8310588
5508748	5508771	11	-	27260156	PANC1	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.10013061690722824	[1206]	[997,1160,1127,657]	-2	hSpCas9	negative selection	8310589
5507623	5507646	11	-	27260156	PANC0813	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.05775841218694833	[19]	[26,3,57,9]	0	hSpCas9	negative selection	8367589
5507626	5507649	11	+	27260156	PANC0813	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.4558124909821466	[954]	[1656,1552,1565,1394]	7	hSpCas9	negative selection	8367590
5507968	5507991	11	+	27260156	PANC0813	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	1.3035803941273478	[248]	[707,1046,480,651]	9	hSpCas9	negative selection	8367591
5509393	5509416	11	-	27260156	PANC0813	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	-0.022363897432333746	[520]	[686,715,425,587]	0	hSpCas9	negative selection	8431838
5509143	5509166	11	-	27260156	PANC0813	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.40256310780773696	[991]	[1212,927,658,760]	-6	hSpCas9	negative selection	8431839
5508748	5508771	11	-	27260156	PANC0813	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.04088374153697094	[1206]	[1569,1652,996,1309]	0	hSpCas9	negative selection	8431840
5507623	5507646	11	-	27260156	RDES	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.5716728034147227	[19]	[17,3,26,12]	-7	hSpCas9	negative selection	8488840
5507626	5507649	11	+	27260156	RDES	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.07954105104144982	[954]	[947,1030,1275,1460]	1	hSpCas9	negative selection	8488841
5507968	5507991	11	+	27260156	RDES	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.6505121484825995	[248]	[332,454,351,704]	9	hSpCas9	negative selection	8488842
5509393	5509416	11	-	27260156	RDES	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.191027456450562	[520]	[702,606,677,734]	3	hSpCas9	negative selection	8553089
5509143	5509166	11	-	27260156	RDES	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.061308299661435584	[991]	[904,1174,1148,1153]	-1	hSpCas9	negative selection	8553090
5508748	5508771	11	-	27260156	RDES	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.04031620691802518	[1206]	[1336,1355,1427,1592]	0	hSpCas9	negative selection	8553091
5507623	5507646	11	-	27260156	PC3	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.8832817675333846	[19]	[0,8,48,2]	-9	hSpCas9	negative selection	8610091
5507626	5507649	11	+	27260156	PC3	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.40531226262772413	[954]	[817,1213,2080,1321]	8	hSpCas9	negative selection	8610092
5507968	5507991	11	+	27260156	PC3	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.28257608193907635	[248]	[214,325,445,278]	6	hSpCas9	negative selection	8610093
5509393	5509416	11	-	27260156	PC3	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	-0.030549374230376597	[520]	[456,331,692,591]	0	hSpCas9	negative selection	8674340
5509143	5509166	11	-	27260156	PC3	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.1107432371118292	[991]	[667,962,1050,1040]	-2	hSpCas9	negative selection	8674341
5508748	5508771	11	-	27260156	PC3	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.045890972053932444	[1206]	[757,1219,1849,1481]	1	hSpCas9	negative selection	8674342
5507623	5507646	11	-	27260156	PATU8988T	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-1.1734769548897068	[19]	[10,19,0,2]	-9	hSpCas9	negative selection	8731342
5507626	5507649	11	+	27260156	PATU8988T	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.3476523032449428	[954]	[1185,1224,1003,1298]	6	hSpCas9	negative selection	8731343
5507968	5507991	11	+	27260156	PATU8988T	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.6012257203595202	[248]	[337,546,256,333]	8	hSpCas9	negative selection	8731344
5509393	5509416	11	-	27260156	PATU8988T	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.27072824651725547	[520]	[581,770,371,732]	4	hSpCas9	negative selection	8795591
5509143	5509166	11	-	27260156	PATU8988T	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.1583720551554647	[991]	[752,763,1125,772]	-3	hSpCas9	negative selection	8795592
5508748	5508771	11	-	27260156	PATU8988T	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.05674933082630895	[1206]	[1051,1031,1207,1188]	-1	hSpCas9	negative selection	8795593
5507623	5507646	11	-	27260156	T47D	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.035732342017007035	[19]	[28,11,40,13]	0	hSpCas9	negative selection	8852593
5507626	5507649	11	+	27260156	T47D	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.27608200612545697	[954]	[1395,1112,1402,1500]	6	hSpCas9	negative selection	8852594
5507968	5507991	11	+	27260156	T47D	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.5113289880623091	[248]	[370,420,413,447]	9	hSpCas9	negative selection	8852595
5509393	5509416	11	-	27260156	T47D	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	-0.0045458982235074274	[520]	[621,630,468,700]	0	hSpCas9	negative selection	8916842
5509143	5509166	11	-	27260156	T47D	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	0.033049128067400346	[991]	[1157,1084,1223,1272]	0	hSpCas9	negative selection	8916843
5508748	5508771	11	-	27260156	T47D	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.0435345940975147	[1206]	[1503,1217,1534,1561]	0	hSpCas9	negative selection	8916844
5507623	5507646	11	-	27260156	SU8686	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-1.1216027671249869	[19]	[5,14,4,9]	-8	hSpCas9	negative selection	8973844
5507626	5507649	11	+	27260156	SU8686	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.5744389990702552	[954]	[1439,1260,1341,1636]	8	hSpCas9	negative selection	8973845
5507968	5507991	11	+	27260156	SU8686	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.9494926814503535	[248]	[440,434,545,495]	9	hSpCas9	negative selection	8973846
5509393	5509416	11	-	27260156	SU8686	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	-0.18734232174882842	[520]	[514,382,458,456]	-3	hSpCas9	negative selection	9038093
5509143	5509166	11	-	27260156	SU8686	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.025952120943030232	[991]	[1012,758,928,1216]	0	hSpCas9	negative selection	9038094
5508748	5508771	11	-	27260156	SU8686	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.1961987064975308	[1206]	[987,865,1067,1323]	-3	hSpCas9	negative selection	9038095
5507623	5507646	11	-	27260156	SKES1	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.40487614272024786	[19]	[21,3,0,30]	-7	hSpCas9	negative selection	9095095
5507626	5507649	11	+	27260156	SKES1	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.25498550100517714	[954]	[1307,1368,843,1076]	5	hSpCas9	negative selection	9095096
5507968	5507991	11	+	27260156	SKES1	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.8474768875684757	[248]	[435,514,450,393]	9	hSpCas9	negative selection	9095097
5509393	5509416	11	-	27260156	SKES1	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	-0.0506291379288661	[520]	[495,638,432,455]	-1	hSpCas9	negative selection	9159344
5509143	5509166	11	-	27260156	SKES1	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.11909457243537303	[991]	[980,1059,929,714]	-3	hSpCas9	negative selection	9159345
5508748	5508771	11	-	27260156	SKES1	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.04797173817344169	[1206]	[1060,1328,1217,1055]	-1	hSpCas9	negative selection	9159346
5507623	5507646	11	-	27260156	TOV112D	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	0.09667448178130655	[19]	[1,0,18,55]	2	hSpCas9	negative selection	9216346
5507626	5507649	11	+	27260156	TOV112D	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.28938837394698225	[954]	[1050,1114,1003,1471]	5	hSpCas9	negative selection	9216347
5507968	5507991	11	+	27260156	TOV112D	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.47624607205566555	[248]	[454,454,280,234]	8	hSpCas9	negative selection	9216348
5509393	5509416	11	-	27260156	TOV112D	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	-0.34068237141016805	[520]	[345,529,382,411]	-6	hSpCas9	negative selection	9280595
5509143	5509166	11	-	27260156	TOV112D	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.3951661688325733	[991]	[787,812,695,740]	-7	hSpCas9	negative selection	9280596
5508748	5508771	11	-	27260156	TOV112D	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.1603604201838449	[1206]	[1206,1422,1486,1291]	3	hSpCas9	negative selection	9280597
5507623	5507646	11	-	27260156	TC71	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-0.8324025442511784	[19]	[10,18,9,7]	-9	hSpCas9	negative selection	9337597
5507626	5507649	11	+	27260156	TC71	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.22136515380821442	[954]	[1064,1263,1149,1305]	5	hSpCas9	negative selection	9337598
5507968	5507991	11	+	27260156	TC71	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.3640623462318201	[248]	[327,407,335,299]	8	hSpCas9	negative selection	9337599
5509393	5509416	11	-	27260156	TC71	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	-0.17869049079166283	[520]	[499,409,428,645]	-5	hSpCas9	negative selection	9401846
5509143	5509166	11	-	27260156	TC71	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.13976124326638362	[991]	[924,1024,848,1072]	-4	hSpCas9	negative selection	9401847
5508748	5508771	11	-	27260156	TC71	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	-0.1521426001671764	[1206]	[1157,1225,1141,1129]	-4	hSpCas9	negative selection	9401848
5507623	5507646	11	-	27260156	TC32	viability	CATTGCTACGGGGGGCGACGTGG	UBQLN3	ENSG00000175520	-1.0060373364003974	[19]	[8,0,25,6]	-9	hSpCas9	negative selection	9458848
5507626	5507649	11	+	27260156	TC32	viability	CGTCGCCCCCCGTAGCAATGAGG	UBQLN3	ENSG00000175520	0.1752252113830579	[954]	[1202,583,1356,1049]	3	hSpCas9	negative selection	9458849
5507968	5507991	11	+	27260156	TC32	viability	GACCCTGCTCAATCTGCCGCAGG	UBQLN3	ENSG00000175520	0.8558811337212411	[248]	[422,392,440,423]	9	hSpCas9	negative selection	9458850
5509393	5509416	11	-	27260156	TC32	viability	AGAGATATCTCAGCGCTTTAAGG	UBQLN3	ENSG00000175520	0.31957184954938966	[520]	[463,526,728,766]	5	hSpCas9	negative selection	9523097
5509143	5509166	11	-	27260156	TC32	viability	TTTAGCTTAGGTCTCCTCACAGG	UBQLN3	ENSG00000175520	-0.0007374869710097265	[991]	[953,756,1121,931]	0	hSpCas9	negative selection	9523098
5508748	5508771	11	-	27260156	TC32	viability	CCCAATGCTTAACGCAGTCCAGG	UBQLN3	ENSG00000175520	0.004938276802271435	[1206]	[1136,755,1535,1278]	0	hSpCas9	negative selection	9523099
5507698	5507721	11	-	27869803	HPAFII	viability after 27 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	0.15264701001047687	[83]	[83,19,NaN]	1	hSpCas9	negative selection	9541947
5507970	5507993	11	-	27869803	HPAFII	viability after 27 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	-0.7117068017538553	[368]	[124,112,NaN]	-5	hSpCas9	negative selection	9541948
5508099	5508122	11	+	27869803	HPAFII	viability after 27 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.9312655011835593	[390]	[589,226,NaN]	7	hSpCas9	negative selection	9541949
5508341	5508364	11	-	27869803	HPAFII	viability after 27 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.26114846481894033	[201]	[117,134,NaN]	2	hSpCas9	negative selection	9541950
5508842	5508865	11	-	27869803	HPAFII	viability after 27 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.8768758751227019	[357]	[343,346,NaN]	7	hSpCas9	negative selection	9541951
5509006	5509029	11	+	27869803	HPAFII	viability after 27 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	0.27111198867885267	[328]	[355,85,NaN]	2	hSpCas9	negative selection	9541952
5507698	5507721	11	-	27869803	HPAFII	viability after 15 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	0.6350653770600567	[83]	[154,130,NaN]	7	hSpCas9	negative selection	9624396
5507970	5507993	11	-	27869803	HPAFII	viability after 15 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	-0.04979157403587864	[368]	[437,348,NaN]	0	hSpCas9	negative selection	9624397
5508099	5508122	11	+	27869803	HPAFII	viability after 15 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.7172624465438648	[390]	[1029,479,NaN]	7	hSpCas9	negative selection	9624398
5508341	5508364	11	-	27869803	HPAFII	viability after 15 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	-0.09997976350899662	[201]	[307,136,NaN]	-1	hSpCas9	negative selection	9624399
5508842	5508865	11	-	27869803	HPAFII	viability after 15 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.755419200945548	[357]	[934,471,NaN]	8	hSpCas9	negative selection	9624400
5509006	5509029	11	+	27869803	HPAFII	viability after 15 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	-0.12801253106885668	[328]	[465,234,NaN]	-1	hSpCas9	negative selection	9624401
5507698	5507721	11	-	27869803	ASPC1	viability after 36 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	0.7745625393809651	[236]	[113,146,154]	7	hSpCas9	negative selection	9706845
5507970	5507993	11	-	27869803	ASPC1	viability after 36 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	-0.5173519599513255	[773]	[395,187,41]	-5	hSpCas9	negative selection	9706846
5508099	5508122	11	+	27869803	ASPC1	viability after 36 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.7973867110361863	[854]	[391,761,408]	7	hSpCas9	negative selection	9706847
5508341	5508364	11	-	27869803	ASPC1	viability after 36 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	-0.3476442134937983	[627]	[295,157,94]	-4	hSpCas9	negative selection	9706848
5508842	5508865	11	-	27869803	ASPC1	viability after 36 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.6126008421247233	[925]	[605,683,259]	6	hSpCas9	negative selection	9706849
5509006	5509029	11	+	27869803	ASPC1	viability after 36 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	-0.38078617538304804	[877]	[421,87,218]	-4	hSpCas9	negative selection	9706850
5507698	5507721	11	-	27869803	PATU8988S	viability after 35 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	0.3952563566037224	[136]	[101,42,NaN]	4	hSpCas9	negative selection	9789294
5507970	5507993	11	-	27869803	PATU8988S	viability after 35 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	-0.19896799475233976	[702]	[315,176,NaN]	-2	hSpCas9	negative selection	9789295
5508099	5508122	11	+	27869803	PATU8988S	viability after 35 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.04286573585388942	[895]	[260,482,NaN]	0	hSpCas9	negative selection	9789296
5508341	5508364	11	-	27869803	PATU8988S	viability after 35 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	-0.5691549846930899	[522]	[129,153,NaN]	-5	hSpCas9	negative selection	9789297
5508842	5508865	11	-	27869803	PATU8988S	viability after 35 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.40596187990242927	[845]	[649,251,NaN]	4	hSpCas9	negative selection	9789298
5509006	5509029	11	+	27869803	PATU8988S	viability after 35 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	0.3349174675508471	[622]	[306,325,NaN]	4	hSpCas9	negative selection	9789299
5507698	5507721	11	-	27869803	PATU8988S	viability after 31 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	0.34532714905005535	[136]	[75,60,NaN]	4	hSpCas9	negative selection	9871743
5507970	5507993	11	-	27869803	PATU8988S	viability after 31 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	-0.3071637497336313	[702]	[226,225,NaN]	-3	hSpCas9	negative selection	9871744
5508099	5508122	11	+	27869803	PATU8988S	viability after 31 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	0.10190923940926089	[895]	[305,481,NaN]	1	hSpCas9	negative selection	9871745
5508341	5508364	11	-	27869803	PATU8988S	viability after 31 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	-0.4511377064588743	[522]	[64,263,NaN]	-5	hSpCas9	negative selection	9871746
5508842	5508865	11	-	27869803	PATU8988S	viability after 31 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.10518415052731711	[845]	[412,298,NaN]	1	hSpCas9	negative selection	9871747
5509006	5509029	11	+	27869803	PATU8988S	viability after 31 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	0.5564931930179855	[622]	[290,459,NaN]	6	hSpCas9	negative selection	9871748
5507698	5507721	11	-	27869803	HPAFII	viability after 35 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	0.23556481806755247	[83]	[66,30,NaN]	1	hSpCas9	negative selection	9954192
5507970	5507993	11	-	27869803	HPAFII	viability after 35 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	-1.4052305949844561	[368]	[70,69,NaN]	-6	hSpCas9	negative selection	9954193
5508099	5508122	11	+	27869803	HPAFII	viability after 35 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	1.0269161503754654	[390]	[376,432,NaN]	7	hSpCas9	negative selection	9954194
5508341	5508364	11	-	27869803	HPAFII	viability after 35 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.2064234663362678	[201]	[101,135,NaN]	1	hSpCas9	negative selection	9954195
5508842	5508865	11	-	27869803	HPAFII	viability after 35 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.5547337874292813	[357]	[229,306,NaN]	3	hSpCas9	negative selection	9954196
5509006	5509029	11	+	27869803	HPAFII	viability after 35 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	1.0250170797358857	[328]	[567,80,NaN]	7	hSpCas9	negative selection	9954197
5507698	5507721	11	-	27869803	HPAFII	viability after 31 days	GGCTCACTTTCAGGTGCAGCTGG	UBQLN3	ENSG00000175520	0.4899687445365113	[83]	[81,48,NaN]	3	hSpCas9	negative selection	10036641
5507970	5507993	11	-	27869803	HPAFII	viability after 31 days	GCCCTGCGGCAGATTGAGCAGGG	UBQLN3	ENSG00000175520	-0.35508298219129114	[368]	[170,151,NaN]	-2	hSpCas9	negative selection	10036642
5508099	5508122	11	+	27869803	HPAFII	viability after 31 days	CTCAGAGATCTTGGATAAGCCGG	UBQLN3	ENSG00000175520	1.1068440261236752	[390]	[474,469,NaN]	7	hSpCas9	negative selection	10036643
5508341	5508364	11	-	27869803	HPAFII	viability after 31 days	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.4414108354407996	[201]	[107,203,NaN]	3	hSpCas9	negative selection	10036644
5508842	5508865	11	-	27869803	HPAFII	viability after 31 days	AGATGATACGTAGCCAGGACCGG	UBQLN3	ENSG00000175520	0.9714503049372716	[357]	[325,467,NaN]	7	hSpCas9	negative selection	10036645
5509006	5509029	11	+	27869803	HPAFII	viability after 31 days	CTGTGTTGGACAGCAGACCCGGG	UBQLN3	ENSG00000175520	0.6436048791137072	[328]	[465,94,NaN]	5	hSpCas9	negative selection	10036646
5509459	5509482	11	-	28162770	P31FUJ	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	-0.6645184448398528	[115]	[85]	-5	hSpCas9	negative selection	10260691
5507886	5507909	11	-	28162770	P31FUJ	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	0.05803531235920675	[196]	[240]	0	hSpCas9	negative selection	10260692
5507761	5507784	11	+	28162770	P31FUJ	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	0.33604063094350034	[119]	[177]	3	hSpCas9	negative selection	10260693
5509369	5509392	11	+	28162770	P31FUJ	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.3669953374697197	[257]	[390]	4	hSpCas9	negative selection	10260694
5509276	5509299	11	+	28162770	P31FUJ	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	0.7297230901669585	[155]	[303]	8	hSpCas9	negative selection	10260695
5508341	5508364	11	-	28162770	P31FUJ	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.472102180519529	[272]	[444]	5	hSpCas9	negative selection	10260696
5508285	5508308	11	-	28162770	P31FUJ	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	0.13619772423585055	[198]	[256]	1	hSpCas9	negative selection	10260697
5508267	5508290	11	-	28162770	P31FUJ	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	0.10668426185728841	[195]	[247]	1	hSpCas9	negative selection	10260698
5508146	5508169	11	+	28162770	P31FUJ	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	0.855965652791874	[259]	[552]	8	hSpCas9	negative selection	10260699
5508101	5508124	11	+	28162770	P31FUJ	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	-0.03065846692173607	[245]	[282]	0	hSpCas9	negative selection	10260700
5509459	5509482	11	-	28162770	TF1	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10430057
5507886	5507909	11	-	28162770	TF1	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	NaN	[NaN]	[148]	1	hSpCas9	negative selection	10430058
5507761	5507784	11	+	28162770	TF1	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10430059
5509369	5509392	11	+	28162770	TF1	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	NaN	[NaN]	[218]	1	hSpCas9	negative selection	10430060
5509276	5509299	11	+	28162770	TF1	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	NaN	[NaN]	[250]	1	hSpCas9	negative selection	10430061
5508341	5508364	11	-	28162770	TF1	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	NaN	[NaN]	[358]	1	hSpCas9	negative selection	10430062
5508285	5508308	11	-	28162770	TF1	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10430063
5508267	5508290	11	-	28162770	TF1	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10430064
5508146	5508169	11	+	28162770	TF1	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	NaN	[NaN]	[357]	1	hSpCas9	negative selection	10430065
5508101	5508124	11	+	28162770	TF1	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	NaN	[NaN]	[172]	1	hSpCas9	negative selection	10430066
5509459	5509482	11	-	28162770	SKM1	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	1.2986280071635332	[42]	[186]	9	hSpCas9	negative selection	10599423
5507886	5507909	11	-	28162770	SKM1	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	0.44648713790389644	[43]	[105]	4	hSpCas9	negative selection	10599424
5507761	5507784	11	+	28162770	SKM1	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	0.17799830197799466	[36]	[73]	1	hSpCas9	negative selection	10599425
5509369	5509392	11	+	28162770	SKM1	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	-0.011826256902022658	[72]	[127]	0	hSpCas9	negative selection	10599426
5509276	5509299	11	+	28162770	SKM1	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	0.9981772643931823	[63]	[225]	8	hSpCas9	negative selection	10599427
5508341	5508364	11	-	28162770	SKM1	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.24408749243576688	[95]	[200]	2	hSpCas9	negative selection	10599428
5508285	5508308	11	-	28162770	SKM1	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	-0.10697865673647636	[52]	[86]	-1	hSpCas9	negative selection	10599429
5508267	5508290	11	-	28162770	SKM1	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	-0.118983435779137	[42]	[69]	-1	hSpCas9	negative selection	10599430
5508146	5508169	11	+	28162770	SKM1	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	0.45553227750690334	[65]	[159]	4	hSpCas9	negative selection	10599431
5508101	5508124	11	+	28162770	SKM1	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	-0.07197995103035287	[43]	[73]	0	hSpCas9	negative selection	10599432
5509459	5509482	11	-	28162770	SKM1	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	1.2986280071635332	[42]	[186]	9	hSpCas9	negative selection	10768789
5507886	5507909	11	-	28162770	SKM1	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	0.44648713790389644	[43]	[105]	4	hSpCas9	negative selection	10768790
5507761	5507784	11	+	28162770	SKM1	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	0.17799830197799466	[36]	[73]	1	hSpCas9	negative selection	10768791
5509369	5509392	11	+	28162770	SKM1	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	-0.011826256902022658	[72]	[127]	0	hSpCas9	negative selection	10768792
5509276	5509299	11	+	28162770	SKM1	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	0.9981772643931823	[63]	[225]	8	hSpCas9	negative selection	10768793
5508341	5508364	11	-	28162770	SKM1	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.24408749243576688	[95]	[200]	2	hSpCas9	negative selection	10768794
5508285	5508308	11	-	28162770	SKM1	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	-0.10697865673647636	[52]	[86]	-1	hSpCas9	negative selection	10768795
5508267	5508290	11	-	28162770	SKM1	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	-0.118983435779137	[42]	[69]	-1	hSpCas9	negative selection	10768796
5508146	5508169	11	+	28162770	SKM1	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	0.45553227750690334	[65]	[159]	4	hSpCas9	negative selection	10768797
5508101	5508124	11	+	28162770	SKM1	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	-0.07197995103035287	[43]	[73]	0	hSpCas9	negative selection	10768798
5509459	5509482	11	-	28162770	PL21	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	0.2261348230222644	[109]	[55]	2	hSpCas9	negative selection	10938155
5507886	5507909	11	-	28162770	PL21	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	1.77204596238503	[147]	[219]	9	hSpCas9	negative selection	10938156
5507761	5507784	11	+	28162770	PL21	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	-1.9120698890967047	[146]	[16]	-8	hSpCas9	negative selection	10938157
5509369	5509392	11	+	28162770	PL21	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.693179625769437	[242]	[170]	6	hSpCas9	negative selection	10938158
5509276	5509299	11	+	28162770	PL21	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	-0.4173907486882666	[223]	[72]	-3	hSpCas9	negative selection	10938159
5508341	5508364	11	-	28162770	PL21	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.9208033963264257	[266]	[219]	7	hSpCas9	negative selection	10938160
5508285	5508308	11	-	28162770	PL21	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	0.3903620301648603	[148]	[84]	3	hSpCas9	negative selection	10938161
5508267	5508290	11	-	28162770	PL21	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	1.5104797351014707	[149]	[185]	9	hSpCas9	negative selection	10938162
5508146	5508169	11	+	28162770	PL21	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	0.9166411060958108	[212]	[174]	7	hSpCas9	negative selection	10938163
5508101	5508124	11	+	28162770	PL21	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	0.41426441984216766	[199]	[115]	3	hSpCas9	negative selection	10938164
5509459	5509482	11	-	28162770	P31FUJ	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	-0.6645184448398528	[115]	[85]	-5	hSpCas9	negative selection	11107521
5507886	5507909	11	-	28162770	P31FUJ	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	0.05803531235920675	[196]	[240]	0	hSpCas9	negative selection	11107522
5507761	5507784	11	+	28162770	P31FUJ	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	0.33604063094350034	[119]	[177]	3	hSpCas9	negative selection	11107523
5509369	5509392	11	+	28162770	P31FUJ	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.3669953374697197	[257]	[390]	4	hSpCas9	negative selection	11107524
5509276	5509299	11	+	28162770	P31FUJ	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	0.7297230901669585	[155]	[303]	8	hSpCas9	negative selection	11107525
5508341	5508364	11	-	28162770	P31FUJ	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.472102180519529	[272]	[444]	5	hSpCas9	negative selection	11107526
5508285	5508308	11	-	28162770	P31FUJ	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	0.13619772423585055	[198]	[256]	1	hSpCas9	negative selection	11107527
5508267	5508290	11	-	28162770	P31FUJ	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	0.10668426185728841	[195]	[247]	1	hSpCas9	negative selection	11107528
5508146	5508169	11	+	28162770	P31FUJ	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	0.855965652791874	[259]	[552]	8	hSpCas9	negative selection	11107529
5508101	5508124	11	+	28162770	P31FUJ	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	-0.03065846692173607	[245]	[282]	0	hSpCas9	negative selection	11107530
5509459	5509482	11	-	28162770	OCIAML5	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	-0.0815484169867643	[101]	[173]	0	hSpCas9	negative selection	11276887
5507886	5507909	11	-	28162770	OCIAML5	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	-0.33180975953065617	[75]	[108]	-2	hSpCas9	negative selection	11276888
5507761	5507784	11	+	28162770	OCIAML5	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	-0.44242233035537193	[66]	[88]	-3	hSpCas9	negative selection	11276889
5509369	5509392	11	+	28162770	OCIAML5	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.8918350705125857	[82]	[277]	7	hSpCas9	negative selection	11276890
5509276	5509299	11	+	28162770	OCIAML5	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	0.6839863293762128	[59]	[173]	6	hSpCas9	negative selection	11276891
5508341	5508364	11	-	28162770	OCIAML5	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.827413528641449	[127]	[409]	7	hSpCas9	negative selection	11276892
5508285	5508308	11	-	28162770	OCIAML5	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	0.6200018734512256	[92]	[257]	5	hSpCas9	negative selection	11276893
5508267	5508290	11	-	28162770	OCIAML5	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	0.1985595022059709	[125]	[260]	1	hSpCas9	negative selection	11276894
5508146	5508169	11	+	28162770	OCIAML5	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	1.2403796779005978	[101]	[434]	9	hSpCas9	negative selection	11276895
5508101	5508124	11	+	28162770	OCIAML5	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	0.8892379590265466	[165]	[554]	7	hSpCas9	negative selection	11276896
5509459	5509482	11	-	28162770	EOL1	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	-0.37028666243455277	[210]	[85]	-3	hSpCas9	negative selection	11446253
5507886	5507909	11	-	28162770	EOL1	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	-0.5608790555997072	[223]	[79]	-4	hSpCas9	negative selection	11446254
5507761	5507784	11	+	28162770	EOL1	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	-0.32407619133909304	[258]	[108]	-2	hSpCas9	negative selection	11446255
5509369	5509392	11	+	28162770	EOL1	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	-0.04985240519316897	[390]	[198]	0	hSpCas9	negative selection	11446256
5509276	5509299	11	+	28162770	EOL1	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	1.6059657045631637	[322]	[517]	9	hSpCas9	negative selection	11446257
5508341	5508364	11	-	28162770	EOL1	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.6188089147825023	[575]	[465]	5	hSpCas9	negative selection	11446258
5508285	5508308	11	-	28162770	EOL1	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	-0.008338032570928355	[146]	[76]	0	hSpCas9	negative selection	11446259
5508267	5508290	11	-	28162770	EOL1	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	1.041587192760754	[141]	[153]	8	hSpCas9	negative selection	11446260
5508146	5508169	11	+	28162770	EOL1	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	1.5646518264841518	[307]	[479]	9	hSpCas9	negative selection	11446261
5508101	5508124	11	+	28162770	EOL1	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	-0.37864376073524186	[305]	[123]	-3	hSpCas9	negative selection	11446262
5509459	5509482	11	-	28162770	MOLM13	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	-0.46937486310745846	[179]	[93]	-3	hSpCas9	negative selection	11615619
5507886	5507909	11	-	28162770	MOLM13	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	0.09813276156660136	[229]	[177]	0	hSpCas9	negative selection	11615620
5507761	5507784	11	+	28162770	MOLM13	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	-0.18746244706797544	[188]	[119]	-1	hSpCas9	negative selection	11615621
5509369	5509392	11	+	28162770	MOLM13	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.5271865652283508	[285]	[297]	4	hSpCas9	negative selection	11615622
5509276	5509299	11	+	28162770	MOLM13	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	1.6179148255491862	[218]	[485]	9	hSpCas9	negative selection	11615623
5508341	5508364	11	-	28162770	MOLM13	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	1.920646546772581	[452]	[1239]	9	hSpCas9	negative selection	11615624
5508285	5508308	11	-	28162770	MOLM13	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	0.7782295021567294	[224]	[278]	6	hSpCas9	negative selection	11615625
5508267	5508290	11	-	28162770	MOLM13	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	1.352412164124643	[168]	[311]	9	hSpCas9	negative selection	11615626
5508146	5508169	11	+	28162770	MOLM13	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	-0.08133890744336424	[318]	[217]	0	hSpCas9	negative selection	11615627
5508101	5508124	11	+	28162770	MOLM13	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	0.3015769254655291	[348]	[310]	2	hSpCas9	negative selection	11615628
5509459	5509482	11	-	28162770	HEL	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	0.19943748050279175	[188]	[138]	1	hSpCas9	negative selection	11784985
5507886	5507909	11	-	28162770	HEL	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	0.41890587630469417	[166]	[142]	3	hSpCas9	negative selection	11784986
5507761	5507784	11	+	28162770	HEL	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	-0.6587251603272899	[174]	[70]	-4	hSpCas9	negative selection	11784987
5509369	5509392	11	+	28162770	HEL	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.8305988473773759	[301]	[343]	7	hSpCas9	negative selection	11784988
5509276	5509299	11	+	28162770	HEL	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	0.9309267150624889	[198]	[242]	7	hSpCas9	negative selection	11784989
5508341	5508364	11	-	28162770	HEL	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.9918130689008422	[536]	[683]	8	hSpCas9	negative selection	11784990
5508285	5508308	11	-	28162770	HEL	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	-0.03263896394301766	[213]	[133]	0	hSpCas9	negative selection	11784991
5508267	5508290	11	-	28162770	HEL	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	0.4488590984063219	[166]	[145]	4	hSpCas9	negative selection	11784992
5508146	5508169	11	+	28162770	HEL	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	0.8797780293012061	[251]	[296]	7	hSpCas9	negative selection	11784993
5508101	5508124	11	+	28162770	HEL	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	-0.12144823090087367	[213]	[125]	-1	hSpCas9	negative selection	11784994
5509459	5509482	11	-	28162770	MV411	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	1.0118093022896333	[72]	[123]	8	hSpCas9	negative selection	11954351
5507886	5507909	11	-	28162770	MV411	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	-0.8040927498573066	[113]	[54]	-5	hSpCas9	negative selection	11954352
5507761	5507784	11	+	28162770	MV411	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	0.6861263181262645	[120]	[163]	6	hSpCas9	negative selection	11954353
5509369	5509392	11	+	28162770	MV411	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.025045129446327426	[174]	[149]	0	hSpCas9	negative selection	11954354
5509276	5509299	11	+	28162770	MV411	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	0.6421219881054518	[231]	[304]	6	hSpCas9	negative selection	11954355
5508341	5508364	11	-	28162770	MV411	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.873707025660845	[240]	[371]	7	hSpCas9	negative selection	11954356
5508285	5508308	11	-	28162770	MV411	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	0.8475864553186073	[125]	[190]	7	hSpCas9	negative selection	11954357
5508267	5508290	11	-	28162770	MV411	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	1.449581288275418	[122]	[282]	9	hSpCas9	negative selection	11954358
5508146	5508169	11	+	28162770	MV411	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	0.3946635039659531	[241]	[267]	3	hSpCas9	negative selection	11954359
5508101	5508124	11	+	28162770	MV411	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	0.9643117270095124	[187]	[308]	8	hSpCas9	negative selection	11954360
5509459	5509482	11	-	28162770	MONOMAC1	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	-0.14154173446785023	[50]	[52]	-1	hSpCas9	negative selection	12123717
5507886	5507909	11	-	28162770	MONOMAC1	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	0.43244432044024717	[116]	[180]	4	hSpCas9	negative selection	12123718
5507761	5507784	11	+	28162770	MONOMAC1	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	0.23430246454839065	[65]	[88]	2	hSpCas9	negative selection	12123719
5509369	5509392	11	+	28162770	MONOMAC1	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	0.13494491249173166	[142]	[179]	1	hSpCas9	negative selection	12123720
5509276	5509299	11	+	28162770	MONOMAC1	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	-0.10017530780696457	[143]	[153]	-1	hSpCas9	negative selection	12123721
5508341	5508364	11	-	28162770	MONOMAC1	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.9432107479710939	[190]	[420]	8	hSpCas9	negative selection	12123722
5508285	5508308	11	-	28162770	MONOMAC1	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	0.0734150303367232	[96]	[116]	0	hSpCas9	negative selection	12123723
5508267	5508290	11	-	28162770	MONOMAC1	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	0.5846175646667001	[88]	[152]	6	hSpCas9	negative selection	12123724
5508146	5508169	11	+	28162770	MONOMAC1	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	1.530147726314067	[147]	[489]	9	hSpCas9	negative selection	12123725
5508101	5508124	11	+	28162770	MONOMAC1	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	0.3256413754072599	[141]	[203]	3	hSpCas9	negative selection	12123726
5509459	5509482	11	-	28162770	OCIAML2	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	-0.2893000605275995	[27]	[126]	-2	hSpCas9	negative selection	12293083
5507886	5507909	11	-	28162770	OCIAML2	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	-0.9787767289124863	[31]	[89]	-6	hSpCas9	negative selection	12293084
5507761	5507784	11	+	28162770	OCIAML2	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	0.5164311190503406	[27]	[221]	5	hSpCas9	negative selection	12293085
5509369	5509392	11	+	28162770	OCIAML2	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	1.1835471702102833	[38]	[490]	9	hSpCas9	negative selection	12293086
5509276	5509299	11	+	28162770	OCIAML2	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	0.2766041043778721	[41]	[281]	2	hSpCas9	negative selection	12293087
5508341	5508364	11	-	28162770	OCIAML2	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	0.1396120839273528	[65]	[402]	1	hSpCas9	negative selection	12293088
5508285	5508308	11	-	28162770	OCIAML2	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	-0.19309584971325236	[32]	[159]	-2	hSpCas9	negative selection	12293089
5508267	5508290	11	-	28162770	OCIAML2	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	0.6278600381572021	[22]	[196]	6	hSpCas9	negative selection	12293090
5508146	5508169	11	+	28162770	OCIAML2	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	0.45625224555382327	[42]	[326]	4	hSpCas9	negative selection	12293091
5508101	5508124	11	+	28162770	OCIAML2	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	-0.18769586197066265	[44]	[218]	-1	hSpCas9	negative selection	12293092
5509459	5509482	11	-	28162770	OCIAML3	viability	GAAGACGCCCAAAGACAAGGAGG	UBQLN3	ENSG00000175520	-0.7925533197062433	[34]	[60]	-5	hSpCas9	negative selection	12462449
5507886	5507909	11	-	28162770	OCIAML3	viability	GGGACGGGTAGTGTGGCAGGAGG	UBQLN3	ENSG00000175520	-0.27652545046799293	[64]	[161]	-2	hSpCas9	negative selection	12462450
5507761	5507784	11	+	28162770	OCIAML3	viability	GCAGCATATGGAGAAAGGGAGGG	UBQLN3	ENSG00000175520	1.0580690562555302	[34]	[219]	8	hSpCas9	negative selection	12462451
5509369	5509392	11	+	28162770	OCIAML3	viability	TTAGAACAAGCTGATCGGGGTGG	UBQLN3	ENSG00000175520	-0.3390105535557876	[74]	[178]	-3	hSpCas9	negative selection	12462452
5509276	5509299	11	+	28162770	OCIAML3	viability	GCTGCCTCTTGATGACCAGGTGG	UBQLN3	ENSG00000175520	1.3784065280039373	[32]	[258]	9	hSpCas9	negative selection	12462453
5508341	5508364	11	-	28162770	OCIAML3	viability	AGTCAGTAGCAATCAAGGGAAGG	UBQLN3	ENSG00000175520	-0.055031344877187416	[84]	[246]	0	hSpCas9	negative selection	12462454
5508285	5508308	11	-	28162770	OCIAML3	viability	GAGAACAGTACTGGACAAGGTGG	UBQLN3	ENSG00000175520	0.21334728173344097	[47]	[167]	2	hSpCas9	negative selection	12462455
5508267	5508290	11	-	28162770	OCIAML3	viability	GGTGGAGACCAAGATGGTGCAGG	UBQLN3	ENSG00000175520	0.31672502157874954	[49]	[187]	3	hSpCas9	negative selection	12462456
5508146	5508169	11	+	28162770	OCIAML3	viability	GATTCCAGGAATGGCTGCCGTGG	UBQLN3	ENSG00000175520	-0.12007645199175082	[53]	[149]	-1	hSpCas9	negative selection	12462457
5508101	5508124	11	+	28162770	OCIAML3	viability	CAGAGATCTTGGATAAGCCGGGG	UBQLN3	ENSG00000175520	0.1221993936752457	[48]	[160]	1	hSpCas9	negative selection	12462458