Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:7369
• Symbol:UMOD
• Description:uromodulin

DataSource: http://genomecrispr.dkfz.de/#!/results/UMOD

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
20348727	20348750	16	-	26472758	Jiyoye	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	-0.5783250487990116	[98]	[49]	-4	hSpCas9	negative selection	177506
20349007	20349030	16	+	26472758	Jiyoye	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	-0.6748603873601379	[198]	[93]	-5	hSpCas9	negative selection	177507
20346148	20346171	16	-	26472758	Jiyoye	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	0.854096941804503	[178]	[243]	6	hSpCas9	negative selection	177508
20349171	20349194	16	-	26472758	Jiyoye	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	-0.07825144566436834	[139]	[99]	0	hSpCas9	negative selection	177509
20348807	20348830	16	-	26472758	Jiyoye	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	-0.4036685266316107	[206]	[117]	-3	hSpCas9	negative selection	177510
20348632	20348655	16	+	26472758	Jiyoye	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	-0.14921796701851187	[74]	[50]	-1	hSpCas9	negative selection	177511
20346239	20346262	16	-	26472758	Jiyoye	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	-1.5470209288810022	[61]	[15]	-7	hSpCas9	negative selection	177512
20350698	20350721	16	-	26472758	Jiyoye	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.1464111492969069	[253]	[211]	1	hSpCas9	negative selection	177513
20349094	20349117	16	+	26472758	Jiyoye	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	0.37951903860300784	[157]	[154]	3	hSpCas9	negative selection	177514
20349070	20349093	16	+	26472758	Jiyoye	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	-0.057615152970069916	[235]	[170]	0	hSpCas9	negative selection	177515
20348727	20348750	16	-	26472758	KBM7	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	0.05753184275671569	[424,314]	[156,198]	0	hSpCas9	negative selection	368624
20349007	20349030	16	+	26472758	KBM7	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	0.7700010636853825	[572,721]	[474,574]	8	hSpCas9	negative selection	368625
20346148	20346171	16	-	26472758	KBM7	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	-0.07393356236143084	[860,526]	[390,225]	0	hSpCas9	negative selection	368626
20349171	20349194	16	-	26472758	KBM7	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.3162769622723857	[470,339]	[269,202]	3	hSpCas9	negative selection	368627
20348807	20348830	16	-	26472758	KBM7	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	0.41246811971870523	[857,483]	[532,299]	4	hSpCas9	negative selection	368628
20348632	20348655	16	+	26472758	KBM7	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	0.7583854781833446	[234,189]	[148,184]	8	hSpCas9	negative selection	368629
20346239	20346262	16	-	26472758	KBM7	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	-0.249127685800008	[173,97]	[51,52]	-2	hSpCas9	negative selection	368630
20350698	20350721	16	-	26472758	KBM7	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.4646523903689135	[1300,1387]	[699,1039]	5	hSpCas9	negative selection	368631
20349094	20349117	16	+	26472758	KBM7	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	0.7768164170367746	[586,726]	[525,547]	8	hSpCas9	negative selection	368632
20349070	20349093	16	+	26472758	KBM7	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	0.052585127896718986	[770,684]	[352,355]	0	hSpCas9	negative selection	368633
20348727	20348750	16	-	26472758	Raji	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	-0.35773919534155363	[126]	[22]	-3	hSpCas9	negative selection	559742
20349007	20349030	16	+	26472758	Raji	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	0.19194783063207232	[380]	[100]	1	hSpCas9	negative selection	559743
20346148	20346171	16	-	26472758	Raji	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	0.5820639810798454	[307]	[106]	5	hSpCas9	negative selection	559744
20349171	20349194	16	-	26472758	Raji	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.4531583722153296	[191]	[60]	4	hSpCas9	negative selection	559745
20348807	20348830	16	-	26472758	Raji	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	0.9761390020953469	[229]	[104]	8	hSpCas9	negative selection	559746
20348632	20348655	16	+	26472758	Raji	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	0.6303363738193308	[102]	[36]	6	hSpCas9	negative selection	559747
20346239	20346262	16	-	26472758	Raji	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	-0.5706883697390381	[63]	[9]	-4	hSpCas9	negative selection	559748
20350698	20350721	16	-	26472758	Raji	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	-0.14278871952314476	[803]	[168]	-1	hSpCas9	negative selection	559749
20349094	20349117	16	+	26472758	Raji	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	-0.16847491081777805	[338]	[69]	-1	hSpCas9	negative selection	559750
20349070	20349093	16	+	26472758	Raji	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	0.2053917391779202	[440]	[117]	2	hSpCas9	negative selection	559751
20348727	20348750	16	-	26472758	K562	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	-0.49081805258300837	[277]	[166]	-3	hSpCas9	negative selection	750860
20349007	20349030	16	+	26472758	K562	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	0.3005436023837793	[604]	[628]	2	hSpCas9	negative selection	750861
20346148	20346171	16	-	26472758	K562	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	-0.1814836592039194	[621]	[462]	-1	hSpCas9	negative selection	750862
20349171	20349194	16	-	26472758	K562	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	-1.073196374349833	[333]	[133]	-5	hSpCas9	negative selection	750863
20348807	20348830	16	-	26472758	K562	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	1.2726156194970988	[379]	[774]	9	hSpCas9	negative selection	750864
20348632	20348655	16	+	26472758	K562	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	2.271385775266716	[105]	[431]	9	hSpCas9	negative selection	750865
20346239	20346262	16	-	26472758	K562	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	0.8293812283876028	[61]	[92]	7	hSpCas9	negative selection	750866
20350698	20350721	16	-	26472758	K562	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.6007450535527776	[1234]	[1580]	5	hSpCas9	negative selection	750867
20349094	20349117	16	+	26472758	K562	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	0.49696075968259834	[459]	[547]	4	hSpCas9	negative selection	750868
20349070	20349093	16	+	26472758	K562	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	-0.014276742443009582	[663]	[554]	0	hSpCas9	negative selection	750869
20344028	20344051	16	-	26627737	DLD1	viability	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	-1.3312525533049082	[352]	[72,17,39]	-8	hSpCas9	negative selection	792974
20346123	20346146	16	+	26627737	DLD1	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.015639826752477076	[542]	[185,155,171]	0	hSpCas9	negative selection	792975
20348238	20348261	16	-	26627737	DLD1	viability	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	0.3788573077477194	[414]	[208,78,207]	4	hSpCas9	negative selection	792976
20348974	20348997	16	+	26627737	DLD1	viability	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.7270023478139338	[641]	[338,509,178]	7	hSpCas9	negative selection	792977
20349844	20349867	16	-	26627737	DLD1	viability	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	0.8057936840048094	[452]	[356,193,196]	7	hSpCas9	negative selection	792978
20350672	20350695	16	+	26627737	DLD1	viability	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.5475372083774753	[564]	[293,320,174]	5	hSpCas9	negative selection	792979
20344028	20344051	16	-	26627737	GBM cells	viability after 5 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	0.009472250033384144	[112]	[57,63]	0	hSpCas9	negative selection	875289
20346123	20346146	16	+	26627737	GBM cells	viability after 5 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.061919462388207336	[208]	[131,101]	1	hSpCas9	negative selection	875290
20348238	20348261	16	-	26627737	GBM cells	viability after 5 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.1808133175850486	[185]	[90,84]	-3	hSpCas9	negative selection	875291
20348974	20348997	16	+	26627737	GBM cells	viability after 5 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.3565575455423895	[366]	[224,278]	5	hSpCas9	negative selection	875292
20349844	20349867	16	-	26627737	GBM cells	viability after 5 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	0.48520788935238635	[360]	[297,243]	7	hSpCas9	negative selection	875293
20350672	20350695	16	+	26627737	GBM cells	viability after 5 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.2820084816617753	[410]	[254,280]	4	hSpCas9	negative selection	875294
20344028	20344051	16	-	26627737	GBM cells	viability after 13 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	0.44651747741527714	[112]	[82,83]	5	hSpCas9	negative selection	957604
20346123	20346146	16	+	26627737	GBM cells	viability after 13 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.03646952053346991	[208]	[171,70]	0	hSpCas9	negative selection	957605
20348238	20348261	16	-	26627737	GBM cells	viability after 13 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	0.10028529476822123	[185]	[132,87]	1	hSpCas9	negative selection	957606
20348974	20348997	16	+	26627737	GBM cells	viability after 13 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.39722538259567575	[366]	[264,259]	5	hSpCas9	negative selection	957607
20349844	20349867	16	-	26627737	GBM cells	viability after 13 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	0.6225085573302689	[360]	[300,301]	7	hSpCas9	negative selection	957608
20350672	20350695	16	+	26627737	GBM cells	viability after 13 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	-0.0160641910654844	[410]	[246,198]	0	hSpCas9	negative selection	957609
20344028	20344051	16	-	26627737	GBM cells	viability after 21 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	0.9969539658538384	[112]	[121,122]	8	hSpCas9	negative selection	1039919
20346123	20346146	16	+	26627737	GBM cells	viability after 21 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.04802621802740398	[208]	[119,114]	0	hSpCas9	negative selection	1039920
20348238	20348261	16	-	26627737	GBM cells	viability after 21 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.11391816114900177	[185]	[107,79]	-1	hSpCas9	negative selection	1039921
20348974	20348997	16	+	26627737	GBM cells	viability after 21 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.6939512044063365	[366]	[344,301]	7	hSpCas9	negative selection	1039922
20349844	20349867	16	-	26627737	GBM cells	viability after 21 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	0.7623117773445918	[360]	[316,346]	7	hSpCas9	negative selection	1039923
20350672	20350695	16	+	26627737	GBM cells	viability after 21 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.2205310371907283	[410]	[267,252]	2	hSpCas9	negative selection	1039924
20344028	20344051	16	-	26627737	RPE1	viability after 9 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	0.34053382888588557	[425]	[136,209]	2	hSpCas9	negative selection	1122234
20346123	20346146	16	+	26627737	RPE1	viability after 9 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.11230016164053525	[386]	[91,137]	-1	hSpCas9	negative selection	1122235
20348238	20348261	16	-	26627737	RPE1	viability after 9 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.29298788133810055	[665]	[105,252]	-2	hSpCas9	negative selection	1122236
20348974	20348997	16	+	26627737	RPE1	viability after 9 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.7514507116865278	[1355]	[615,841]	5	hSpCas9	negative selection	1122237
20349844	20349867	16	-	26627737	RPE1	viability after 9 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	2.1253707856358486	[615]	[1150,441]	9	hSpCas9	negative selection	1122238
20350672	20350695	16	+	26627737	RPE1	viability after 9 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	-0.5774009963979755	[1931]	[238,619]	-4	hSpCas9	negative selection	1122239
20344028	20344051	16	-	26627737	RPE1	viability after 12 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	-0.6158377997022335	[425]	[97,49]	-4	hSpCas9	negative selection	1204549
20346123	20346146	16	+	26627737	RPE1	viability after 12 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.010236121604935366	[386]	[111,96]	0	hSpCas9	negative selection	1204550
20348238	20348261	16	-	26627737	RPE1	viability after 12 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.7026568885730489	[665]	[73,147]	-5	hSpCas9	negative selection	1204551
20348974	20348997	16	+	26627737	RPE1	viability after 12 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.9208847496683404	[1355]	[663,716]	6	hSpCas9	negative selection	1204552
20349844	20349867	16	-	26627737	RPE1	viability after 12 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	2.2792482144548845	[615]	[1104,483]	9	hSpCas9	negative selection	1204553
20350672	20350695	16	+	26627737	RPE1	viability after 12 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	-0.3121130291057538	[1931]	[386,450]	-2	hSpCas9	negative selection	1204554
20344028	20344051	16	-	26627737	RPE1	viability after 15 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	-1.7135104605062872	[425]	[22,49]	-8	hSpCas9	negative selection	1286864
20346123	20346146	16	+	26627737	RPE1	viability after 15 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.5473204792486606	[386]	[107,42]	-3	hSpCas9	negative selection	1286865
20348238	20348261	16	-	26627737	RPE1	viability after 15 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.764684653998029	[665]	[60,158]	-5	hSpCas9	negative selection	1286866
20348974	20348997	16	+	26627737	RPE1	viability after 15 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	1.112575723495636	[1355]	[917,743]	6	hSpCas9	negative selection	1286867
20349844	20349867	16	-	26627737	RPE1	viability after 15 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	2.5028273210521985	[615]	[1231,751]	9	hSpCas9	negative selection	1286868
20350672	20350695	16	+	26627737	RPE1	viability after 15 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	-0.6488159814424762	[1931]	[231,460]	-4	hSpCas9	negative selection	1286869
20344028	20344051	16	-	26627737	RPE1	viability after 18 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	0.004960270149475754	[425]	[154,72]	0	hSpCas9	negative selection	1369179
20346123	20346146	16	+	26627737	RPE1	viability after 18 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.2300200204249263	[386]	[104,71]	-1	hSpCas9	negative selection	1369180
20348238	20348261	16	-	26627737	RPE1	viability after 18 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.41036435311389213	[665]	[112,158]	-3	hSpCas9	negative selection	1369181
20348974	20348997	16	+	26627737	RPE1	viability after 18 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.919658850315978	[1355]	[640,746]	5	hSpCas9	negative selection	1369182
20349844	20349867	16	-	26627737	RPE1	viability after 18 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	2.2975091063807014	[615]	[940,684]	9	hSpCas9	negative selection	1369183
20350672	20350695	16	+	26627737	RPE1	viability after 18 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	-0.22647680997294928	[1931]	[303,596]	-1	hSpCas9	negative selection	1369184
20344028	20344051	16	-	26627737	HeLa	viability after 8 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	0.9970515701640345	[122]	[111,152,59]	7	hSpCas9	negative selection	1451494
20346123	20346146	16	+	26627737	HeLa	viability after 8 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.7380560437062105	[331]	[277,11,16]	-6	hSpCas9	negative selection	1451495
20348238	20348261	16	-	26627737	HeLa	viability after 8 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	0.2556528613501493	[345]	[178,119,235]	2	hSpCas9	negative selection	1451496
20348974	20348997	16	+	26627737	HeLa	viability after 8 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.7970423297695893	[465]	[496,345,252]	6	hSpCas9	negative selection	1451497
20349844	20349867	16	-	26627737	HeLa	viability after 8 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	0.7309552375873749	[354]	[488,217,122]	6	hSpCas9	negative selection	1451498
20350672	20350695	16	+	26627737	HeLa	viability after 8 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.32240089985908216	[824]	[193,698,400]	3	hSpCas9	negative selection	1451499
20344028	20344051	16	-	26627737	HeLa	viability after 12 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	-1.0935796234709592	[122]	[2,12,55]	-7	hSpCas9	negative selection	1533809
20346123	20346146	16	+	26627737	HeLa	viability after 12 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.09841050718166197	[331]	[95,176,162]	0	hSpCas9	negative selection	1533810
20348238	20348261	16	-	26627737	HeLa	viability after 12 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	0.41081581739669026	[345]	[313,122,143]	3	hSpCas9	negative selection	1533811
20348974	20348997	16	+	26627737	HeLa	viability after 12 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.5513127167484818	[465]	[240,342,254]	4	hSpCas9	negative selection	1533812
20349844	20349867	16	-	26627737	HeLa	viability after 12 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	1.1066739789387166	[354]	[193,308,441]	7	hSpCas9	negative selection	1533813
20350672	20350695	16	+	26627737	HeLa	viability after 12 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	-0.9011459408370335	[824]	[116,255,164]	-7	hSpCas9	negative selection	1533814
20344028	20344051	16	-	26627737	HeLa	viability after 15 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	-0.40615054637903536	[122]	[0,60,52]	-4	hSpCas9	negative selection	1616124
20346123	20346146	16	+	26627737	HeLa	viability after 15 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.459475641970161	[331]	[109,268,178]	4	hSpCas9	negative selection	1616125
20348238	20348261	16	-	26627737	HeLa	viability after 15 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.12944584162508138	[345]	[123,125,136]	-1	hSpCas9	negative selection	1616126
20348974	20348997	16	+	26627737	HeLa	viability after 15 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.8043423457433042	[465]	[350,294,348]	6	hSpCas9	negative selection	1616127
20349844	20349867	16	-	26627737	HeLa	viability after 15 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	1.2545011703687994	[354]	[279,328,432]	8	hSpCas9	negative selection	1616128
20350672	20350695	16	+	26627737	HeLa	viability after 15 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	-0.41285808036981875	[824]	[162,269,330]	-4	hSpCas9	negative selection	1616129
20344028	20344051	16	-	26627737	HeLa	viability after 18 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	-0.346149329546513	[122]	[0,53,52]	-3	hSpCas9	negative selection	1698439
20346123	20346146	16	+	26627737	HeLa	viability after 18 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.4690317308193338	[331]	[75,222,178]	4	hSpCas9	negative selection	1698440
20348238	20348261	16	-	26627737	HeLa	viability after 18 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.057898462999002726	[345]	[96,102,136]	0	hSpCas9	negative selection	1698441
20348974	20348997	16	+	26627737	HeLa	viability after 18 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.8107672600513457	[465]	[236,245,348]	6	hSpCas9	negative selection	1698442
20349844	20349867	16	-	26627737	HeLa	viability after 18 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	1.2467208958329596	[354]	[182,273,432]	8	hSpCas9	negative selection	1698443
20350672	20350695	16	+	26627737	HeLa	viability after 18 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	-0.42591537833462834	[824]	[102,225,330]	-4	hSpCas9	negative selection	1698444
20344028	20344051	16	-	26627737	HCT116	viability after 6 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	-1.8544331936551985	[207]	[19,2]	-8	hSpCas9	negative selection	1780754
20346123	20346146	16	+	26627737	HCT116	viability after 6 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.20951224574744587	[334]	[18,83]	1	hSpCas9	negative selection	1780755
20348238	20348261	16	-	26627737	HCT116	viability after 6 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.3010294599398422	[432]	[149,2]	-2	hSpCas9	negative selection	1780756
20348974	20348997	16	+	26627737	HCT116	viability after 6 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.03069582623386935	[1034]	[249,119]	0	hSpCas9	negative selection	1780757
20349844	20349867	16	-	26627737	HCT116	viability after 6 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	1.6071256747898794	[492]	[384,153]	8	hSpCas9	negative selection	1780758
20350672	20350695	16	+	26627737	HCT116	viability after 6 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.7814478322856464	[892]	[288,214]	4	hSpCas9	negative selection	1780759
20344028	20344051	16	-	26627737	HCT116	viability after 8 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	0.47650348910242113	[109]	[54,155,41]	5	hSpCas9	negative selection	1863069
20346123	20346146	16	+	26627737	HCT116	viability after 8 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.3524600707764508	[202]	[98,72,90]	-4	hSpCas9	negative selection	1863070
20348238	20348261	16	-	26627737	HCT116	viability after 8 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.4157579316892343	[352]	[133,138,163]	-5	hSpCas9	negative selection	1863071
20348974	20348997	16	+	26627737	HCT116	viability after 8 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.8551236207482282	[356]	[482,329,257]	7	hSpCas9	negative selection	1863072
20349844	20349867	16	-	26627737	HCT116	viability after 8 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	1.165549737469155	[236]	[316,164,395]	8	hSpCas9	negative selection	1863073
20350672	20350695	16	+	26627737	HCT116	viability after 8 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.05781971566554156	[663]	[529,300,314]	0	hSpCas9	negative selection	1863074
20344028	20344051	16	-	26627737	HCT116	viability after 9 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	-0.17518053733051464	[207]	[13,76]	-1	hSpCas9	negative selection	1945384
20346123	20346146	16	+	26627737	HCT116	viability after 9 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	1.1698336445753976	[334]	[50,319]	7	hSpCas9	negative selection	1945385
20348238	20348261	16	-	26627737	HCT116	viability after 9 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.35504004695906577	[432]	[57,115]	-3	hSpCas9	negative selection	1945386
20348974	20348997	16	+	26627737	HCT116	viability after 9 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	-0.2553042335130248	[1034]	[254,212]	-2	hSpCas9	negative selection	1945387
20349844	20349867	16	-	26627737	HCT116	viability after 9 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	0.611308783299696	[492]	[285,133]	4	hSpCas9	negative selection	1945388
20350672	20350695	16	+	26627737	HCT116	viability after 9 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.5920863885258336	[892]	[421,309]	4	hSpCas9	negative selection	1945389
20344028	20344051	16	-	26627737	HCT116	viability after 12 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	0.5203919723794415	[109]	[116,92,35]	5	hSpCas9	negative selection	2027699
20346123	20346146	16	+	26627737	HCT116	viability after 12 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.505439869416253	[202]	[172,174,104]	5	hSpCas9	negative selection	2027700
20348238	20348261	16	-	26627737	HCT116	viability after 12 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.21523138374263598	[352]	[212,170,90]	-2	hSpCas9	negative selection	2027701
20348974	20348997	16	+	26627737	HCT116	viability after 12 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.7880133487019847	[356]	[270,426,280]	7	hSpCas9	negative selection	2027702
20349844	20349867	16	-	26627737	HCT116	viability after 12 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	1.3306377771654379	[236]	[262,263,415]	8	hSpCas9	negative selection	2027703
20350672	20350695	16	+	26627737	HCT116	viability after 12 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	-0.6971297336840747	[663]	[368,124,135]	-6	hSpCas9	negative selection	2027704
20344028	20344051	16	-	26627737	HCT116	viability after 15 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	0.6869324326665983	[109]	[127,136,43]	6	hSpCas9	negative selection	2110014
20346123	20346146	16	+	26627737	HCT116	viability after 15 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	1.1305525121651203	[202]	[188,256,310]	8	hSpCas9	negative selection	2110015
20348238	20348261	16	-	26627737	HCT116	viability after 15 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.6816117878287935	[352]	[135,88,154]	-6	hSpCas9	negative selection	2110016
20348974	20348997	16	+	26627737	HCT116	viability after 15 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.7888402121109646	[356]	[357,341,362]	7	hSpCas9	negative selection	2110017
20349844	20349867	16	-	26627737	HCT116	viability after 15 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	1.0797656358562544	[236]	[408,111,355]	8	hSpCas9	negative selection	2110018
20350672	20350695	16	+	26627737	HCT116	viability after 15 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	-0.19206415578519964	[663]	[593,99,338]	-2	hSpCas9	negative selection	2110019
20344028	20344051	16	-	26627737	HCT116	viability after 18 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	0.45163538051233165	[109]	[118,80,14]	4	hSpCas9	negative selection	2192329
20346123	20346146	16	+	26627737	HCT116	viability after 18 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	1.0203309457357994	[202]	[144,222,228]	7	hSpCas9	negative selection	2192330
20348238	20348261	16	-	26627737	HCT116	viability after 18 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	0.11854863154456474	[352]	[177,220,152]	1	hSpCas9	negative selection	2192331
20348974	20348997	16	+	26627737	HCT116	viability after 18 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.938363480199728	[356]	[374,288,330]	7	hSpCas9	negative selection	2192332
20349844	20349867	16	-	26627737	HCT116	viability after 18 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	1.5411018332733568	[236]	[335,240,433]	9	hSpCas9	negative selection	2192333
20350672	20350695	16	+	26627737	HCT116	viability after 18 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.15752886132343558	[663]	[613,219,243]	1	hSpCas9	negative selection	2192334
20355477	20355500	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCCACCTCCCAAG	UMOD	ENSG00000169344	-1.4516426362223873	[480,182]	[29,20]	-8	dCas9-VP64	positive selection	2426985
20353030	20353053	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTCTTCTTGGTCACTGACAAGG	UMOD	ENSG00000169344	0.7276366311040479	[287,207]	[164,8]	3	dCas9-VP64	positive selection	2432729
20353000	20353023	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TAACTGGGAAAGCAGTGCCAAGG	UMOD	ENSG00000169344	0.035896722149289406	[10,0]	[0,0]	0	dCas9-VP64	positive selection	2432730
20352966	20352989	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGAATCTCTTGCTGTTAGAAGG	UMOD	ENSG00000169344	-1.0847505223805747	[354,186]	[42,10]	-6	dCas9-VP64	positive selection	2432731
20355477	20355500	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCCACCTCCCAAG	UMOD	ENSG00000169344	1.047613524569726	[257,163]	[245,45]	6	dCas9-VP64	positive selection	2522240
20353030	20353053	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTCTTCTTGGTCACTGACAAGG	UMOD	ENSG00000169344	0.9721267112881706	[225,245]	[41,252]	6	dCas9-VP64	positive selection	2527984
20353000	20353023	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TAACTGGGAAAGCAGTGCCAAGG	UMOD	ENSG00000169344	-0.18423594821297673	[38,20]	[12,3]	-2	dCas9-VP64	positive selection	2527985
20352966	20352989	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGAATCTCTTGCTGTTAGAAGG	UMOD	ENSG00000169344	-1.2886308168050629	[255,129]	[31,18]	-9	dCas9-VP64	positive selection	2527986
20348871	20348894	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGCCCCGCGGGCTACCGGGGGG	UMOD	ENSG00000169344	-0.2567531488117004	[1,1]	[1,0]	-4	hSpCas9	positive selection	3030961
20348857	20348880	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CACAGTGCCATCCATCCCCCCGG	UMOD	ENSG00000169344	0.21225377054798455	[5,5]	[5,5]	4	hSpCas9	positive selection	3030962
20349171	20349194	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	-0.10489476162084188	[1,2]	[2,0]	-1	hSpCas9	positive selection	3030963
20348883	20348906	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	-0.2759586667874364	[3,3]	[1,2]	-4	hSpCas9	positive selection	3030964
20348871	20348894	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGCCCCGCGGGCTACCGGGGGG	UMOD	ENSG00000169344	0.596806976920669	[1,1]	[3,0]	8	hSpCas9	positive selection	3098819
20348857	20348880	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CACAGTGCCATCCATCCCCCCGG	UMOD	ENSG00000169344	0.12874971860289308	[5,5]	[5,3]	2	hSpCas9	positive selection	3098820
20349171	20349194	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.28542385583708385	[1,1]	[2,0]	5	hSpCas9	positive selection	3098821
20348883	20348906	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	-0.2898098314252721	[3,3]	[3,0]	-4	hSpCas9	positive selection	3098822
20348222	20348245		-	24336571	A375	resistance to PLX after 7 days	AAACAGGACTTCAACATCACTGG	UMOD	ENSG00000169344	0.0025186715272284	[22,16]	[15,22]	0	hSpCas9	positive selection	3154306
20348257	20348280		-	24336571	A375	resistance to PLX after 7 days	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	0.7018861985879918	[5,5]	[10,7]	9	hSpCas9	positive selection	3154307
20346123	20346146		+	24336571	A375	resistance to PLX after 7 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.06579787108083712	[26,27]	[27,24]	-2	hSpCas9	positive selection	3154310
20346194	20346217		+	24336571	A375	resistance to PLX after 7 days	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.20344333228408476	[8,10]	[9,11]	6	hSpCas9	positive selection	3154311
20348222	20348245		-	24336571	A375	resistance to PLX after 14 days	AAACAGGACTTCAACATCACTGG	UMOD	ENSG00000169344	-0.12123088443658131	[22,14]	[8,6]	-1	hSpCas9	positive selection	3212099
20348257	20348280		-	24336571	A375	resistance to PLX after 14 days	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	1.7654496514788551	[11,7]	[12,18]	9	hSpCas9	positive selection	3212100
20346123	20346146		+	24336571	A375	resistance to PLX after 14 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.8885216912119787	[27,21]	[5,5]	-9	hSpCas9	positive selection	3212103
20346194	20346217		+	24336571	A375	resistance to PLX after 14 days	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.1880989249886484	[9,10]	[6,3]	2	hSpCas9	positive selection	3212104
20348222	20348245		-	24336571	A375	viability after 7 days	AAACAGGACTTCAACATCACTGG	UMOD	ENSG00000169344	-0.16753119307438924	[22]	[22,16]	-2	hSpCas9	negative selection	3269892
20348257	20348280		-	24336571	A375	viability after 7 days	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.21256311441510822	[6]	[5,5]	-3	hSpCas9	negative selection	3269893
20346123	20346146		+	24336571	A375	viability after 7 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.3792411064603044	[21]	[26,27]	6	hSpCas9	negative selection	3269896
20346194	20346217		+	24336571	A375	viability after 7 days	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	-0.2587716970171501	[11]	[8,10]	-4	hSpCas9	negative selection	3269897
20348222	20348245		-	24336571	A375	viability after 14 days	AAACAGGACTTCAACATCACTGG	UMOD	ENSG00000169344	-0.2005824002704123	[22]	[22,14]	-2	hSpCas9	negative selection	3327685
20348257	20348280		-	24336571	A375	viability after 14 days	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	0.5346561828924749	[6]	[11,7]	6	hSpCas9	negative selection	3327686
20346123	20346146		+	24336571	A375	viability after 14 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.27543582714546144	[21]	[27,21]	3	hSpCas9	negative selection	3327689
20346194	20346217		+	24336571	A375	viability after 14 days	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	-0.10903527473893032	[11]	[9,10]	-1	hSpCas9	negative selection	3327690
20337419	20337442	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	1.107579091941153	[70,70]	[0,0]	5	hSpCas9	positive selection	3400307
20348283	20348306	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	0.9905396707509337	[76,76]	[0,0]	4	hSpCas9	positive selection	3400308
20348257	20348280	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	0.4244361972810935	[113,113]	[0,0]	2	hSpCas9	positive selection	3400309
20348871	20348894	16	-	26780180	HT29	viability (Avana library 4 designs)	ATGCCCCGCGGGCTACCGGGGGG	UMOD	ENSG00000169344	1.08335939233151	[]	[]	4	hSpCas9	negative selection	3469912
20348856	20348879	16	+	26780180	HT29	viability (Avana library 4 designs)	CACAGTGCCATCCATCCCCCCGG	UMOD	ENSG00000169344	0.183477728988219	[]	[]	0	hSpCas9	negative selection	3469913
20349171	20349194	16	-	26780180	HT29	viability (Avana library 4 designs)	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	2.03420113096553	[]	[]	7	hSpCas9	negative selection	3469914
20348883	20348906	16	-	26780180	HT29	viability (Avana library 4 designs)	CTACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	0.57180813398063	[]	[]	2	hSpCas9	negative selection	3469915
20348883	20348906	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	5.51054388952638	[]	[]	8	hSpCas9	negative selection	3575363
20348871	20348894	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGCCCCGCGGGCTACCGGGGGG	UMOD	ENSG00000169344	3.92153079981796	[]	[]	6	hSpCas9	negative selection	3575364
20349171	20349194	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	-0.998726903030922	[]	[]	-1	hSpCas9	negative selection	3575365
20348856	20348879	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	CACAGTGCCATCCATCCCCCCGG	UMOD	ENSG00000169344	2.94852385869653	[]	[]	4	hSpCas9	negative selection	3575366
20350672	20350695	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	-0.848635801901581	[]	[]	-1	hSpCas9	negative selection	3575367
20348709	20348732	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGGGCTACGCCTGCGACACGG	UMOD	ENSG00000169344	6.8561531033557	[]	[]	9	hSpCas9	negative selection	3575368
20348883	20348906	16	-	26780180	A375	viability (Avana lentiGuide)	CTACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	-0.492404238027399	[]	[]	0	hSpCas9	negative selection	3684022
20348871	20348894	16	-	26780180	A375	viability (Avana lentiGuide)	ATGCCCCGCGGGCTACCGGGGGG	UMOD	ENSG00000169344	1.81505354879644	[]	[]	2	hSpCas9	negative selection	3684023
20349171	20349194	16	-	26780180	A375	viability (Avana lentiGuide)	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	8.1376677974673	[]	[]	6	hSpCas9	negative selection	3684024
20348856	20348879	16	+	26780180	A375	viability (Avana lentiGuide)	CACAGTGCCATCCATCCCCCCGG	UMOD	ENSG00000169344	-1.89576387593674	[]	[]	-3	hSpCas9	negative selection	3684025
20350672	20350695	16	+	26780180	A375	viability (Avana lentiGuide)	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	2.56329346086155	[]	[]	2	hSpCas9	negative selection	3684026
20348709	20348732	16	-	26780180	A375	viability (Avana lentiGuide)	GGAGGGCTACGCCTGCGACACGG	UMOD	ENSG00000169344	5.45029216459326	[]	[]	5	hSpCas9	negative selection	3684027
20348883	20348906	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	0.34005072658790547	[4]	[6,6]	8	hSpCas9	positive selection	3792629
20348871	20348894	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGCCCCGCGGGCTACCGGGGGG	UMOD	ENSG00000169344	0.14187091369972937	[3]	[4,3]	4	hSpCas9	positive selection	3792630
20349171	20349194	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	-0.44166745867236135	[3]	[1,2]	-6	hSpCas9	positive selection	3792631
20348856	20348879	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACAGTGCCATCCATCCCCCCGG	UMOD	ENSG00000169344	0.15180595458406415	[5]	[6,5]	4	hSpCas9	positive selection	3792632
20350672	20350695	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.0016063946694343523	[5]	[6,5]	0	hSpCas9	positive selection	3792633
20348709	20348732	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGGGCTACGCCTGCGACACGG	UMOD	ENSG00000169344	0.25798992667456394	[4]	[6,4]	7	hSpCas9	positive selection	3792634
20348883	20348906	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	-0.35828490735586266	[5]	[2,4]	-5	hSpCas9	positive selection	3901236
20348871	20348894	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGCCCCGCGGGCTACCGGGGGG	UMOD	ENSG00000169344	-0.5880895158609657	[3]	[2,0]	-6	hSpCas9	positive selection	3901237
20349171	20349194	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	-0.3380587080538551	[3]	[2,1]	-4	hSpCas9	positive selection	3901238
20348856	20348879	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACAGTGCCATCCATCCCCCCGG	UMOD	ENSG00000169344	0.23860638702924314	[7]	[7,7]	6	hSpCas9	positive selection	3901239
20350672	20350695	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.21230611119110526	[6]	[6,6]	5	hSpCas9	positive selection	3901240
20348709	20348732	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGGGCTACGCCTGCGACACGG	UMOD	ENSG00000169344	0.11134249939564037	[4]	[4,4]	2	hSpCas9	positive selection	3901241
20348257	20348280	16	-	26780180	A375	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	1.00060074285545	[]	[]	4	hSpCas9	negative selection	4010344
20346123	20346146	16	+	26780180	A375	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.822700374204775	[]	[]	3	hSpCas9	negative selection	4010345
20337419	20337442	16	-	26780180	A375	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.760172827959382	[]	[]	3	hSpCas9	negative selection	4010346
20337377	20337400	16	+	26780180	A375	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	1.26777692532846	[]	[]	7	hSpCas9	negative selection	4010347
20348283	20348306	16	-	26780180	A375	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	0.82176142790403	[]	[]	3	hSpCas9	negative selection	4010348
20346194	20346217	16	+	26780180	A375	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.868218225757359	[]	[]	3	hSpCas9	negative selection	4010349
20348257	20348280	16	-	26780180	HT29	viability (GeCKOv2 library)	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	1.14958614590859	[]	[]	5	hSpCas9	negative selection	4118310
20346123	20346146	16	+	26780180	HT29	viability (GeCKOv2 library)	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	1.76967058120657	[]	[]	8	hSpCas9	negative selection	4118311
20337419	20337442	16	-	26780180	HT29	viability (GeCKOv2 library)	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.836158158716708	[]	[]	3	hSpCas9	negative selection	4118312
20337377	20337400	16	+	26780180	HT29	viability (GeCKOv2 library)	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	1.43325544410008	[]	[]	7	hSpCas9	negative selection	4118313
20348283	20348306	16	-	26780180	HT29	viability (GeCKOv2 library)	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	1.05038112783193	[]	[]	5	hSpCas9	negative selection	4118314
20346194	20346217	16	+	26780180	HT29	viability (GeCKOv2 library)	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.987758514250389	[]	[]	4	hSpCas9	negative selection	4118315
20348222	20348245	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAACAGGACTTCAACATCACTGG	UMOD	ENSG00000169344	0.4361180105182271	[4]	[5,2]	8	hSpCas9	positive selection	4181003
20348257	20348280	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	0.6861449907307962	[2]	[1,3]	9	hSpCas9	positive selection	4181004
20346123	20346146	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.14481432787100804	[4]	[2,2]	-3	hSpCas9	positive selection	4181007
20346194	20346217	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	-0.06046267527380114	[3]	[1,2]	-1	hSpCas9	positive selection	4181008
20348222	20348245	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAACAGGACTTCAACATCACTGG	UMOD	ENSG00000169344	-0.30030899444062953	[4]	[2,0,2,0]	-4	hSpCas9	positive selection	4245025
20348257	20348280	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.3571831333595312	[3]	[0,2,0,0]	-5	hSpCas9	positive selection	4245026
20346123	20346146	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	1.188553079345957	[4]	[3,4,3,4]	8	hSpCas9	positive selection	4245029
20346194	20346217	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	-0.6332498371944839	[2]	[0,0,0,0]	-8	hSpCas9	positive selection	4245030
20337377	20337400	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.49561729635925034	[2]	[2,2]	8	hSpCas9	positive selection	4306596
20346194	20346217	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	-0.15918927151367768	[4]	[3,1]	-3	hSpCas9	positive selection	4306597
20346123	20346146	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.32894392114322973	[3]	[2,1]	-6	hSpCas9	positive selection	4306598
20337419	20337442	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.17214462270209974	[1]	[1,1]	3	hSpCas9	positive selection	4370844
20348283	20348306	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	0.8292245561835148	[2]	[2,3]	9	hSpCas9	positive selection	4370845
20348257	20348280	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	0.2665206770858321	[2]	[2,2]	5	hSpCas9	positive selection	4370846
20348442	20348464	16	+	27760321	OCIAML3	viability	AGTACGCCAGGTGACACTCGGG	UMOD	ENSG00000169344	-0.45817497712393696	[444,426]	[189,324]	-5	hSpCas9	negative selection	4452286
20348483	20348505	16	+	27760321	OCIAML3	viability	ACGTAGTAGCCGCCGGCACAGG	UMOD	ENSG00000169344	-0.523796630139619	[705,611]	[268,472]	-5	hSpCas9	negative selection	4452287
20348579	20348601	16	-	27760321	OCIAML3	viability	CGCATCCGTCCAGCGACGAGGG	UMOD	ENSG00000169344	0.05854193430382004	[11,14]	[11,9]	0	hSpCas9	negative selection	4452288
20348883	20348905	16	-	27760321	OCIAML3	viability	TACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	0.00500734096003852	[818,729]	[609,602]	0	hSpCas9	negative selection	4452289
20349143	20349165	16	+	27760321	OCIAML3	viability	TGACAGGTGCACGTCGTAACGG	UMOD	ENSG00000169344	0.08632145684083026	[248,224]	[170,229]	1	hSpCas9	negative selection	4452290
20348442	20348464	16	+	27760321	OCIAML2	viability	AGTACGCCAGGTGACACTCGGG	UMOD	ENSG00000169344	-0.6420602052008504	[444,426]	[171,297]	-6	hSpCas9	negative selection	4535749
20348483	20348505	16	+	27760321	OCIAML2	viability	ACGTAGTAGCCGCCGGCACAGG	UMOD	ENSG00000169344	-0.6487192525055603	[705,611]	[314,370]	-6	hSpCas9	negative selection	4535750
20348579	20348601	16	-	27760321	OCIAML2	viability	CGCATCCGTCCAGCGACGAGGG	UMOD	ENSG00000169344	0.25101373782722813	[11,14]	[10,15]	3	hSpCas9	negative selection	4535751
20348883	20348905	16	-	27760321	OCIAML2	viability	TACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	-0.07181922871807322	[818,729]	[577,617]	-1	hSpCas9	negative selection	4535752
20349143	20349165	16	+	27760321	OCIAML2	viability	TGACAGGTGCACGTCGTAACGG	UMOD	ENSG00000169344	0.2815541744092641	[248,224]	[193,283]	4	hSpCas9	negative selection	4535753
20348442	20348464	16	+	27760321	MV411	viability	AGTACGCCAGGTGACACTCGGG	UMOD	ENSG00000169344	0.4518920961384492	[444,426]	[121,802]	3	hSpCas9	negative selection	4619212
20348483	20348505	16	+	27760321	MV411	viability	ACGTAGTAGCCGCCGGCACAGG	UMOD	ENSG00000169344	1.2199058334191175	[705,611]	[1198,726]	8	hSpCas9	negative selection	4619213
20348579	20348601	16	-	27760321	MV411	viability	CGCATCCGTCCAGCGACGAGGG	UMOD	ENSG00000169344	2.5490448650351407	[11,14]	[33,80]	9	hSpCas9	negative selection	4619214
20348883	20348905	16	-	27760321	MV411	viability	TACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	0.7166444629061891	[818,729]	[964,648]	5	hSpCas9	negative selection	4619215
20349143	20349165	16	+	27760321	MV411	viability	TGACAGGTGCACGTCGTAACGG	UMOD	ENSG00000169344	0.2510572389015262	[248,224]	[139,254]	1	hSpCas9	negative selection	4619216
20348442	20348464	16	+	27760321	HL60	viability	AGTACGCCAGGTGACACTCGGG	UMOD	ENSG00000169344	-0.6190480929318226	[444,426]	[240,222]	-6	hSpCas9	negative selection	4702675
20348483	20348505	16	+	27760321	HL60	viability	ACGTAGTAGCCGCCGGCACAGG	UMOD	ENSG00000169344	-0.7005176626946847	[705,611]	[376,280]	-6	hSpCas9	negative selection	4702676
20348579	20348601	16	-	27760321	HL60	viability	CGCATCCGTCCAGCGACGAGGG	UMOD	ENSG00000169344	-0.2712488138255784	[11,14]	[0,17]	-3	hSpCas9	negative selection	4702677
20348883	20348905	16	-	27760321	HL60	viability	TACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	-0.06650023806236094	[818,729]	[629,574]	0	hSpCas9	negative selection	4702678
20349143	20349165	16	+	27760321	HL60	viability	TGACAGGTGCACGTCGTAACGG	UMOD	ENSG00000169344	0.12000618250771178	[248,224]	[183,237]	1	hSpCas9	negative selection	4702679
20348442	20348464	16	+	27760321	HT1080	viability	AGTACGCCAGGTGACACTCGGG	UMOD	ENSG00000169344	0.7384787043985815	[426,332]	[337,158]	4	hSpCas9	negative selection	4786138
20348483	20348505	16	+	27760321	HT1080	viability	ACGTAGTAGCCGCCGGCACAGG	UMOD	ENSG00000169344	0.05703830823417	[611,477]	[275,170]	0	hSpCas9	negative selection	4786139
20348579	20348601	16	-	27760321	HT1080	viability	CGCATCCGTCCAGCGACGAGGG	UMOD	ENSG00000169344	-2.429279739642115	[14,11]	[0,0]	-7	hSpCas9	negative selection	4786140
20348883	20348905	16	-	27760321	HT1080	viability	TACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	0.6308257523348073	[729,569]	[452,343]	3	hSpCas9	negative selection	4786141
20349143	20349165	16	+	27760321	HT1080	viability	TGACAGGTGCACGTCGTAACGG	UMOD	ENSG00000169344	1.6202179379624169	[224,175]	[299,185]	8	hSpCas9	negative selection	4786142
20348442	20348464	16	+	27760321	HT29	viability after 7 days	AGTACGCCAGGTGACACTCGGG	UMOD	ENSG00000169344	-0.345109976310523	[426,332]	[373,400,376]	-5	hSpCas9	negative selection	4869601
20348483	20348505	16	+	27760321	HT29	viability after 7 days	ACGTAGTAGCCGCCGGCACAGG	UMOD	ENSG00000169344	-0.3777311351986681	[611,477]	[583,513,525]	-5	hSpCas9	negative selection	4869602
20348579	20348601	16	-	27760321	HT29	viability after 7 days	CGCATCCGTCCAGCGACGAGGG	UMOD	ENSG00000169344	-0.008894054004534802	[14,11]	[49,5,0]	0	hSpCas9	negative selection	4869603
20348883	20348905	16	-	27760321	HT29	viability after 7 days	TACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	-0.2700174737560055	[729,569]	[854,637,610]	-4	hSpCas9	negative selection	4869604
20349143	20349165	16	+	27760321	HT29	viability after 7 days	TGACAGGTGCACGTCGTAACGG	UMOD	ENSG00000169344	-0.027865685339969692	[224,175]	[354,232,186]	0	hSpCas9	negative selection	4869605
20348442	20348464	16	+	27760321	HT29	viability after 25 days	AGTACGCCAGGTGACACTCGGG	UMOD	ENSG00000169344	0.5141124041156122	[426,332]	[386,713,790]	5	hSpCas9	negative selection	4953064
20348483	20348505	16	+	27760321	HT29	viability after 25 days	ACGTAGTAGCCGCCGGCACAGG	UMOD	ENSG00000169344	-0.08607797152963403	[611,477]	[393,554,849]	-1	hSpCas9	negative selection	4953065
20348579	20348601	16	-	27760321	HT29	viability after 25 days	CGCATCCGTCCAGCGACGAGGG	UMOD	ENSG00000169344	-0.1263554225491461	[14,11]	[13,0,28]	-1	hSpCas9	negative selection	4953066
20348883	20348905	16	-	27760321	HT29	viability after 25 days	TACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	-0.12723321529478004	[729,569]	[353,878,843]	-1	hSpCas9	negative selection	4953067
20349143	20349165	16	+	27760321	HT29	viability after 25 days	TGACAGGTGCACGTCGTAACGG	UMOD	ENSG00000169344	0.43926231359848805	[224,175]	[349,330,240]	5	hSpCas9	negative selection	4953068
20348442	20348464	16	+	27760321	HT29	viability after 22 days	AGTACGCCAGGTGACACTCGGG	UMOD	ENSG00000169344	0.301504500059965	[426,332]	[451,583,590]	3	hSpCas9	negative selection	5036527
20348483	20348505	16	+	27760321	HT29	viability after 22 days	ACGTAGTAGCCGCCGGCACAGG	UMOD	ENSG00000169344	0.2676478467866601	[611,477]	[696,734,845]	2	hSpCas9	negative selection	5036528
20348579	20348601	16	-	27760321	HT29	viability after 22 days	CGCATCCGTCCAGCGACGAGGG	UMOD	ENSG00000169344	0.5234479051494612	[14,11]	[10,3,52]	6	hSpCas9	negative selection	5036529
20348883	20348905	16	-	27760321	HT29	viability after 22 days	TACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	-0.35337105626565035	[729,569]	[325,613,833]	-4	hSpCas9	negative selection	5036530
20349143	20349165	16	+	27760321	HT29	viability after 22 days	TGACAGGTGCACGTCGTAACGG	UMOD	ENSG00000169344	0.16705073020541483	[224,175]	[191,295,294]	1	hSpCas9	negative selection	5036531
20348442	20348464	16	+	27760321	HT29	viability after 19 days	AGTACGCCAGGTGACACTCGGG	UMOD	ENSG00000169344	0.09532091084067634	[426,332]	[689,312,414]	0	hSpCas9	negative selection	5119990
20348483	20348505	16	+	27760321	HT29	viability after 19 days	ACGTAGTAGCCGCCGGCACAGG	UMOD	ENSG00000169344	0.0316292546039415	[611,477]	[661,597,652]	0	hSpCas9	negative selection	5119991
20348579	20348601	16	-	27760321	HT29	viability after 19 days	CGCATCCGTCCAGCGACGAGGG	UMOD	ENSG00000169344	2.9209909118910407	[14,11]	[39,46,250]	9	hSpCas9	negative selection	5119992
20348883	20348905	16	-	27760321	HT29	viability after 19 days	TACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	-0.2167629527252325	[729,569]	[964,703,296]	-2	hSpCas9	negative selection	5119993
20349143	20349165	16	+	27760321	HT29	viability after 19 days	TGACAGGTGCACGTCGTAACGG	UMOD	ENSG00000169344	0.2097862312382277	[224,175]	[283,395,122]	2	hSpCas9	negative selection	5119994
20348442	20348464	16	+	27760321	HT29	viability after 16 days	AGTACGCCAGGTGACACTCGGG	UMOD	ENSG00000169344	0.44146110251191084	[426,332]	[707,392,647]	5	hSpCas9	negative selection	5203453
20348483	20348505	16	+	27760321	HT29	viability after 16 days	ACGTAGTAGCCGCCGGCACAGG	UMOD	ENSG00000169344	-0.2695336195242286	[611,477]	[360,613,525]	-3	hSpCas9	negative selection	5203454
20348579	20348601	16	-	27760321	HT29	viability after 16 days	CGCATCCGTCCAGCGACGAGGG	UMOD	ENSG00000169344	0.23607038049086881	[14,11]	[8,2,40]	2	hSpCas9	negative selection	5203455
20348883	20348905	16	-	27760321	HT29	viability after 16 days	TACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	-0.52732765038521	[729,569]	[545,450,521]	-5	hSpCas9	negative selection	5203456
20349143	20349165	16	+	27760321	HT29	viability after 16 days	TGACAGGTGCACGTCGTAACGG	UMOD	ENSG00000169344	-0.06429693478780685	[224,175]	[287,199,162]	0	hSpCas9	negative selection	5203457
20348442	20348464	16	+	27760321	HT29	viability after 13 days	AGTACGCCAGGTGACACTCGGG	UMOD	ENSG00000169344	-0.3481127604034865	[426,332]	[355,287,391]	-4	hSpCas9	negative selection	5286916
20348483	20348505	16	+	27760321	HT29	viability after 13 days	ACGTAGTAGCCGCCGGCACAGG	UMOD	ENSG00000169344	-0.28689661320773924	[611,477]	[573,537,446]	-4	hSpCas9	negative selection	5286917
20348579	20348601	16	-	27760321	HT29	viability after 13 days	CGCATCCGTCCAGCGACGAGGG	UMOD	ENSG00000169344	-0.2562079191963109	[14,11]	[0,0,35]	-3	hSpCas9	negative selection	5286918
20348883	20348905	16	-	27760321	HT29	viability after 13 days	TACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	-0.47098826202460325	[729,569]	[590,582,462]	-5	hSpCas9	negative selection	5286919
20349143	20349165	16	+	27760321	HT29	viability after 13 days	TGACAGGTGCACGTCGTAACGG	UMOD	ENSG00000169344	0.27876791550381286	[224,175]	[200,383,262]	3	hSpCas9	negative selection	5286920
20348442	20348464	16	+	27760321	HT29	viability after 10 days	AGTACGCCAGGTGACACTCGGG	UMOD	ENSG00000169344	0.28798389151218184	[426,332]	[459,719,561]	4	hSpCas9	negative selection	5370379
20348483	20348505	16	+	27760321	HT29	viability after 10 days	ACGTAGTAGCCGCCGGCACAGG	UMOD	ENSG00000169344	-0.5225429322704385	[611,477]	[576,525,322]	-6	hSpCas9	negative selection	5370380
20348579	20348601	16	-	27760321	HT29	viability after 10 days	CGCATCCGTCCAGCGACGAGGG	UMOD	ENSG00000169344	-1.018277699215579	[14,11]	[8,7,7]	-8	hSpCas9	negative selection	5370381
20348883	20348905	16	-	27760321	HT29	viability after 10 days	TACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	-0.38563165439577857	[729,569]	[537,566,753]	-5	hSpCas9	negative selection	5370382
20349143	20349165	16	+	27760321	HT29	viability after 10 days	TGACAGGTGCACGTCGTAACGG	UMOD	ENSG00000169344	-0.11082719878209601	[224,175]	[178,324,194]	-1	hSpCas9	negative selection	5370383
20348442	20348464	16	+	27760321	MOLM13	viability	AGTACGCCAGGTGACACTCGGG	UMOD	ENSG00000169344	-0.9648647022077649	[444,426]	[102,145]	-5	hSpCas9	negative selection	5453842
20348483	20348505	16	+	27760321	MOLM13	viability	ACGTAGTAGCCGCCGGCACAGG	UMOD	ENSG00000169344	-1.286892048449321	[705,611]	[131,168]	-6	hSpCas9	negative selection	5453843
20348579	20348601	16	-	27760321	MOLM13	viability	CGCATCCGTCCAGCGACGAGGG	UMOD	ENSG00000169344	0.46674056030421074	[11,14]	[21,0]	3	hSpCas9	negative selection	5453844
20348883	20348905	16	-	27760321	MOLM13	viability	TACTTGTGCGTATGCCCCGCGG	UMOD	ENSG00000169344	0.31255303292310754	[818,729]	[623,471]	2	hSpCas9	negative selection	5453845
20349143	20349165	16	+	27760321	MOLM13	viability	TGACAGGTGCACGTCGTAACGG	UMOD	ENSG00000169344	0.21214967893271908	[248,224]	[83,214]	1	hSpCas9	negative selection	5453846
20350549	20350572	16	+	27661255	K562	viability	GGATTGAGATCACCTCTGACAGG	UMOD	ENSG00000169344	-0.08574210338199806	[1313,1185]	[1055,845]	-3	dCas9-KRAB	negative selection	5521507
20337377	20337400	16	+	27260156	BXPC3	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.28305087089336256	[253]	[285,261,361,397]	6	hSpCas9	negative selection	5579056
20346194	20346217	16	+	27260156	BXPC3	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.01862662276352922	[1054]	[1044,1041,1180,1219]	0	hSpCas9	negative selection	5579057
20346123	20346146	16	+	27260156	BXPC3	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.09335993110030594	[869]	[808,887,948,1290]	2	hSpCas9	negative selection	5579058
20337419	20337442	16	-	27260156	BXPC3	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.04533013496885774	[131]	[137,131,157,141]	1	hSpCas9	negative selection	5643304
20348283	20348306	16	-	27260156	BXPC3	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.371991190042104	[198]	[107,136,192,218]	-7	hSpCas9	negative selection	5643305
20348257	20348280	16	-	27260156	BXPC3	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.461702612008274	[359]	[260,285,352,181]	-7	hSpCas9	negative selection	5643306
20337377	20337400	16	+	27260156	A673	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.07013882840550045	[253]	[346,340,216,381]	1	hSpCas9	negative selection	5700307
20346194	20346217	16	+	27260156	A673	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.10090347958566914	[1054]	[1547,1119,1415,1375]	2	hSpCas9	negative selection	5700308
20346123	20346146	16	+	27260156	A673	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.06522612001985884	[869]	[1284,1016,1095,989]	1	hSpCas9	negative selection	5700309
20337419	20337442	16	-	27260156	A673	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.37255223710054386	[131]	[212,268,165,169]	8	hSpCas9	negative selection	5764555
20348283	20348306	16	-	27260156	A673	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.2405064028074937	[198]	[241,172,196,201]	-5	hSpCas9	negative selection	5764556
20348257	20348280	16	-	27260156	A673	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.5606626834144189	[359]	[371,285,223,299]	-8	hSpCas9	negative selection	5764557
20337377	20337400	16	+	27260156	A375	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.2141639336396104	[253]	[307,329,242,475]	3	hSpCas9	negative selection	5821558
20346194	20346217	16	+	27260156	A375	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.20682190983357418	[1054]	[1388,1753,1403,1207]	3	hSpCas9	negative selection	5821559
20346123	20346146	16	+	27260156	A375	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.053719363649680885	[869]	[985,1030,1075,842]	-1	hSpCas9	negative selection	5821560
20337419	20337442	16	-	27260156	A375	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.21893161769509195	[131]	[151,261,177,140]	3	hSpCas9	negative selection	5885806
20348283	20348306	16	-	27260156	A375	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.2629474634626152	[198]	[265,178,211,123]	-4	hSpCas9	negative selection	5885807
20348257	20348280	16	-	27260156	A375	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.17206706553895135	[359]	[489,469,267,287]	-2	hSpCas9	negative selection	5885808
20337377	20337400	16	+	27260156	COLO741	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.8680696575959728	[253]	[550,763,466]	9	hSpCas9	negative selection	5942809
20346194	20346217	16	+	27260156	COLO741	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.16429290406723984	[1054]	[1700,1456,1394]	3	hSpCas9	negative selection	5942810
20346123	20346146	16	+	27260156	COLO741	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.10017023591341567	[869]	[1303,1430,870]	2	hSpCas9	negative selection	5942811
20337419	20337442	16	-	27260156	COLO741	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.01416272765243276	[131]	[236,151,120]	0	hSpCas9	negative selection	6007057
20348283	20348306	16	-	27260156	COLO741	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	0.3130830503792402	[198]	[318,392,240]	6	hSpCas9	negative selection	6007058
20348257	20348280	16	-	27260156	COLO741	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.3012984044393152	[359]	[538,335,265]	-6	hSpCas9	negative selection	6007059
20337377	20337400	16	+	27260156	CAL120	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	-0.24935642456830687	[253]	[447,166,210]	-4	hSpCas9	negative selection	6064060
20346194	20346217	16	+	27260156	CAL120	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	-0.5813692108989177	[1054]	[991,830,826]	-7	hSpCas9	negative selection	6064061
20346123	20346146	16	+	27260156	CAL120	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.5927716460426387	[869]	[578,591,956]	-7	hSpCas9	negative selection	6064062
20337419	20337442	16	-	27260156	CAL120	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.7257445820957351	[131]	[83,188,23]	-7	hSpCas9	negative selection	6128308
20348283	20348306	16	-	27260156	CAL120	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-1.1917193908287402	[198]	[190,115,31]	-9	hSpCas9	negative selection	6128309
20348257	20348280	16	-	27260156	CAL120	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	0.1001939102289387	[359]	[270,326,804]	1	hSpCas9	negative selection	6128310
20337377	20337400	16	+	27260156	CADOES1	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.09607714212454377	[253]	[248,244,288,225]	1	hSpCas9	negative selection	6185311
20346194	20346217	16	+	27260156	CADOES1	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.31853878589380735	[1054]	[1010,1610,1022,1251]	5	hSpCas9	negative selection	6185312
20346123	20346146	16	+	27260156	CADOES1	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.06271596499973742	[869]	[1045,684,817,829]	1	hSpCas9	negative selection	6185313
20337419	20337442	16	-	27260156	CADOES1	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.2998590052981094	[131]	[84,51,106,156]	-5	hSpCas9	negative selection	6249559
20348283	20348306	16	-	27260156	CADOES1	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.16780273706938909	[198]	[300,60,143,151]	-3	hSpCas9	negative selection	6249560
20348257	20348280	16	-	27260156	CADOES1	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.7045973784134827	[359]	[206,218,236,156]	-8	hSpCas9	negative selection	6249561
20337377	20337400	16	+	27260156	EWS502	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.2879956965445106	[253]	[265,420,284,344]	5	hSpCas9	negative selection	6306562
20346194	20346217	16	+	27260156	EWS502	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	-0.004941430688157	[1054]	[1381,979,1083,965]	0	hSpCas9	negative selection	6306563
20346123	20346146	16	+	27260156	EWS502	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.09849641993867919	[869]	[987,830,870,1277]	1	hSpCas9	negative selection	6306564
20337419	20337442	16	-	27260156	EWS502	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.10893674357462779	[131]	[58,228,103,222]	1	hSpCas9	negative selection	6370810
20348283	20348306	16	-	27260156	EWS502	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.17768460955687004	[198]	[184,192,187,177]	-3	hSpCas9	negative selection	6370811
20348257	20348280	16	-	27260156	EWS502	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.19472189327602196	[359]	[282,381,232,443]	-3	hSpCas9	negative selection	6370812
20337377	20337400	16	+	27260156	EW8	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.13932453110612097	[253]	[391,185,199,150]	2	hSpCas9	negative selection	6427813
20346194	20346217	16	+	27260156	EW8	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.17437253216584514	[1054]	[1129,1034,734,1013]	3	hSpCas9	negative selection	6427814
20346123	20346146	16	+	27260156	EW8	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.015218391937302234	[869]	[783,679,578,774]	0	hSpCas9	negative selection	6427815
20337419	20337442	16	-	27260156	EW8	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.009503523767838473	[131]	[116,36,66,210]	0	hSpCas9	negative selection	6492061
20348283	20348306	16	-	27260156	EW8	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.6004078117256582	[198]	[159,133,66,76]	-8	hSpCas9	negative selection	6492062
20348257	20348280	16	-	27260156	EW8	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.057465073006935485	[359]	[279,306,158,394]	-1	hSpCas9	negative selection	6492063
20337377	20337400	16	+	27260156	CORL105	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.2366210105530442	[253]	[306,354,321,410]	4	hSpCas9	negative selection	6549064
20346194	20346217	16	+	27260156	CORL105	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.2552174582431328	[1054]	[1398,1312,1802,1432]	5	hSpCas9	negative selection	6549065
20346123	20346146	16	+	27260156	CORL105	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.0025606423548940604	[869]	[1190,903,1273,746]	0	hSpCas9	negative selection	6549066
20337419	20337442	16	-	27260156	CORL105	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.5609265005111317	[131]	[243,196,334,153]	8	hSpCas9	negative selection	6613312
20348283	20348306	16	-	27260156	CORL105	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.7708920211443286	[198]	[141,182,107,107]	-8	hSpCas9	negative selection	6613313
20348257	20348280	16	-	27260156	CORL105	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.8704615563214426	[359]	[143,249,346,195]	-9	hSpCas9	negative selection	6613314
20337377	20337400	16	+	27260156	HS294T	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.1719610899245605	[253]	[75,215,73,68]	2	hSpCas9	negative selection	6670315
20346194	20346217	16	+	27260156	HS294T	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.2664459494396565	[1054]	[357,523,663,413]	3	hSpCas9	negative selection	6670316
20346123	20346146	16	+	27260156	HS294T	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.7534992673421043	[869]	[531,559,611,565]	8	hSpCas9	negative selection	6670317
20337419	20337442	16	-	27260156	HS294T	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.2355575043115461	[131]	[55,17,54,43]	-3	hSpCas9	negative selection	6734563
20348283	20348306	16	-	27260156	HS294T	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.8358761729110158	[198]	[17,29,59,71]	-8	hSpCas9	negative selection	6734564
20348257	20348280	16	-	27260156	HS294T	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	0.3059709917870254	[359]	[223,108,238,100]	4	hSpCas9	negative selection	6734565
20337377	20337400	16	+	27260156	HCC44	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.46064756381081406	[253]	[445,453,419,262]	7	hSpCas9	negative selection	6791566
20346194	20346217	16	+	27260156	HCC44	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.0384279190984651	[1054]	[1268,1252,1349,1046]	0	hSpCas9	negative selection	6791567
20346123	20346146	16	+	27260156	HCC44	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.14314010658696252	[869]	[1242,889,1164,1094]	2	hSpCas9	negative selection	6791568
20337419	20337442	16	-	27260156	HCC44	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.09047658778716694	[131]	[183,33,168,194]	-1	hSpCas9	negative selection	6855814
20348283	20348306	16	-	27260156	HCC44	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.03175458995802671	[198]	[230,198,252,205]	0	hSpCas9	negative selection	6855815
20348257	20348280	16	-	27260156	HCC44	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.5496809188345215	[359]	[364,305,157,264]	-7	hSpCas9	negative selection	6855816
20337377	20337400	16	+	27260156	G402	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	-0.22582703724605535	[253]	[301,177,306,271]	-3	hSpCas9	negative selection	6912817
20346194	20346217	16	+	27260156	G402	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.12078551175101748	[1054]	[1415,2025,1357,858]	1	hSpCas9	negative selection	6912818
20346123	20346146	16	+	27260156	G402	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.04572098762061749	[869]	[1515,1127,842,960]	0	hSpCas9	negative selection	6912819
20337419	20337442	16	-	27260156	G402	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.5070924328146134	[131]	[44,59,307,30]	-6	hSpCas9	negative selection	6977065
20348283	20348306	16	-	27260156	G402	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.07039333492468347	[198]	[113,379,193,227]	-1	hSpCas9	negative selection	6977066
20348257	20348280	16	-	27260156	G402	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	0.23480828987453076	[359]	[699,274,521,577]	3	hSpCas9	negative selection	6977067
20337377	20337400	16	+	27260156	L33	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.12938899464416953	[253]	[160,113,173,396]	3	hSpCas9	negative selection	7034068
20346194	20346217	16	+	27260156	L33	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.06316820810077228	[1054]	[1105,444,618,1229]	1	hSpCas9	negative selection	7034069
20346123	20346146	16	+	27260156	L33	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.12845052664687862	[869]	[885,366,740,846]	3	hSpCas9	negative selection	7034070
20337419	20337442	16	-	27260156	L33	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.270937444257187	[131]	[221,49,79,163]	6	hSpCas9	negative selection	7098316
20348283	20348306	16	-	27260156	L33	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.10736577242925249	[198]	[97,95,178,124]	-2	hSpCas9	negative selection	7098317
20348257	20348280	16	-	27260156	L33	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.38259256099167493	[359]	[324,109,172,234]	-7	hSpCas9	negative selection	7098318
20337377	20337400	16	+	27260156	K562	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.7521444861603596	[253]	[739,285,356,181]	8	hSpCas9	negative selection	7155319
20346194	20346217	16	+	27260156	K562	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.16227223875553998	[1054]	[992,1418,766,1024]	2	hSpCas9	negative selection	7155320
20346123	20346146	16	+	27260156	K562	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.14539345541428828	[869]	[954,1005,817,670]	1	hSpCas9	negative selection	7155321
20337419	20337442	16	-	27260156	K562	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.5182725528048169	[131]	[20,144,141,23]	-6	hSpCas9	negative selection	7219567
20348283	20348306	16	-	27260156	K562	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.11020980255766966	[198]	[98,243,101,202]	-1	hSpCas9	negative selection	7219568
20348257	20348280	16	-	27260156	K562	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	0.24049728551085772	[359]	[674,318,342,211]	3	hSpCas9	negative selection	7219569
20337377	20337400	16	+	27260156	HT29	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.3438499840861786	[253]	[379,446,291,442]	6	hSpCas9	negative selection	7276570
20346194	20346217	16	+	27260156	HT29	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.0876752958252589	[1054]	[1305,1625,1392,1159]	1	hSpCas9	negative selection	7276571
20346123	20346146	16	+	27260156	HT29	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.21185932728706425	[869]	[1440,1227,1287,980]	4	hSpCas9	negative selection	7276572
20337419	20337442	16	-	27260156	HT29	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.43642675150778554	[131]	[200,267,182,217]	8	hSpCas9	negative selection	7340818
20348283	20348306	16	-	27260156	HT29	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.03302913944137109	[198]	[340,164,302,147]	0	hSpCas9	negative selection	7340819
20348257	20348280	16	-	27260156	HT29	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.4999316029541263	[359]	[393,244,354,249]	-7	hSpCas9	negative selection	7340820
20337377	20337400	16	+	27260156	MHHES1	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.4609659190383494	[253]	[364,472,418,328]	7	hSpCas9	negative selection	7397821
20346194	20346217	16	+	27260156	MHHES1	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.06644984416810362	[1054]	[1490,1014,1243,1211]	1	hSpCas9	negative selection	7397822
20346123	20346146	16	+	27260156	MHHES1	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.1490273823496555	[869]	[1259,920,911,549]	-3	hSpCas9	negative selection	7397823
20337419	20337442	16	-	27260156	MHHES1	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.31412863215753495	[131]	[154,246,213,133]	6	hSpCas9	negative selection	7462069
20348283	20348306	16	-	27260156	MHHES1	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-1.2961739575254037	[198]	[180,71,100,31]	-9	hSpCas9	negative selection	7462070
20348257	20348280	16	-	27260156	MHHES1	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.40862847985596373	[359]	[221,237,313,400]	-6	hSpCas9	negative selection	7462071
20337377	20337400	16	+	27260156	MEWO	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.24500703774105315	[253]	[373,217,270]	5	hSpCas9	negative selection	7519072
20346194	20346217	16	+	27260156	MEWO	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	-0.03530109624757527	[1054]	[1170,866,891]	0	hSpCas9	negative selection	7519073
20346123	20346146	16	+	27260156	MEWO	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.15535821881667122	[869]	[999,630,613]	-3	hSpCas9	negative selection	7519074
20337419	20337442	16	-	27260156	MEWO	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.4271167277098742	[131]	[191,190,119]	8	hSpCas9	negative selection	7583320
20348283	20348306	16	-	27260156	MEWO	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.45987660451288837	[198]	[120,189,91]	-7	hSpCas9	negative selection	7583321
20348257	20348280	16	-	27260156	MEWO	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.7856207912546769	[359]	[229,154,207]	-9	hSpCas9	negative selection	7583322
20337377	20337400	16	+	27260156	LNCAPCLONEFGC	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.2579849084161917	[253]	[264,200,399,257]	4	hSpCas9	negative selection	7640323
20346194	20346217	16	+	27260156	LNCAPCLONEFGC	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	-0.14189891915863662	[1054]	[565,925,1041,957]	-2	hSpCas9	negative selection	7640324
20346123	20346146	16	+	27260156	LNCAPCLONEFGC	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.09592908318663196	[869]	[862,889,801,803]	1	hSpCas9	negative selection	7640325
20337419	20337442	16	-	27260156	LNCAPCLONEFGC	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.2792291634244013	[131]	[48,132,106,104]	-4	hSpCas9	negative selection	7704571
20348283	20348306	16	-	27260156	LNCAPCLONEFGC	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.05596042072027663	[198]	[210,86,223,183]	-1	hSpCas9	negative selection	7704572
20348257	20348280	16	-	27260156	LNCAPCLONEFGC	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.3489967623717607	[359]	[170,136,346,391]	-5	hSpCas9	negative selection	7704573
20337377	20337400	16	+	27260156	PANC0327	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	-0.15076126474901974	[253]	[316,180,135,190]	-2	hSpCas9	negative selection	7761574
20346194	20346217	16	+	27260156	PANC0327	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.07105797962393545	[1054]	[1030,971,956,982]	1	hSpCas9	negative selection	7761575
20346123	20346146	16	+	27260156	PANC0327	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.554527445028343	[869]	[1067,902,1104,1487]	7	hSpCas9	negative selection	7761576
20337419	20337442	16	-	27260156	PANC0327	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.45121862875346674	[131]	[33,61,167,77]	-6	hSpCas9	negative selection	7825822
20348283	20348306	16	-	27260156	PANC0327	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.07937665496755475	[198]	[145,83,115,331]	-1	hSpCas9	negative selection	7825823
20348257	20348280	16	-	27260156	PANC0327	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.7774631760901116	[359]	[160,85,189,319]	-8	hSpCas9	negative selection	7825824
20337377	20337400	16	+	27260156	NCIH2009	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.22854467774597043	[253]	[672,388,235]	3	hSpCas9	negative selection	7882825
20346194	20346217	16	+	27260156	NCIH2009	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.17266942301493438	[1054]	[1956,1651,1430]	2	hSpCas9	negative selection	7882826
20346123	20346146	16	+	27260156	NCIH2009	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.025302857906617904	[869]	[1683,1200,912]	0	hSpCas9	negative selection	7882827
20337419	20337442	16	-	27260156	NCIH2009	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.5517480799782386	[131]	[244,355,202]	7	hSpCas9	negative selection	7947073
20348283	20348306	16	-	27260156	NCIH2009	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.13502195377906978	[198]	[285,177,302]	-2	hSpCas9	negative selection	7947074
20348257	20348280	16	-	27260156	NCIH2009	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.8973358588420888	[359]	[350,250,223]	-8	hSpCas9	negative selection	7947075
20337377	20337400	16	+	27260156	NCIH1373	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.011148717331379232	[253]	[341,160,363,78]	0	hSpCas9	negative selection	8004076
20346194	20346217	16	+	27260156	NCIH1373	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.05196316706240811	[1054]	[1500,1067,1009,365]	0	hSpCas9	negative selection	8004077
20346123	20346146	16	+	27260156	NCIH1373	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.17630303175701167	[869]	[1111,593,908,236]	-2	hSpCas9	negative selection	8004078
20337419	20337442	16	-	27260156	NCIH1373	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.4603192941285579	[131]	[209,34,122,21]	-4	hSpCas9	negative selection	8068324
20348283	20348306	16	-	27260156	NCIH1373	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.21810949455450723	[198]	[146,96,366,39]	-2	hSpCas9	negative selection	8068325
20348257	20348280	16	-	27260156	NCIH1373	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.680074907490005	[359]	[234,180,341,65]	-6	hSpCas9	negative selection	8068326
20337377	20337400	16	+	27260156	PATU8902	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.6655058468584134	[253]	[227,1054,347,684]	7	hSpCas9	negative selection	8125327
20346194	20346217	16	+	27260156	PATU8902	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.04137387979609164	[1054]	[1291,2130,1000,1781]	0	hSpCas9	negative selection	8125328
20346123	20346146	16	+	27260156	PATU8902	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.12456340891064277	[869]	[1207,1474,514,1431]	-1	hSpCas9	negative selection	8125329
20337419	20337442	16	-	27260156	PATU8902	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.16237722045830294	[131]	[65,133,359,29]	-2	hSpCas9	negative selection	8189575
20348283	20348306	16	-	27260156	PATU8902	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.2760372169054546	[198]	[238,129,47,585]	-3	hSpCas9	negative selection	8189576
20348257	20348280	16	-	27260156	PATU8902	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.6357319866184352	[359]	[263,298,465,208]	-6	hSpCas9	negative selection	8189577
20337377	20337400	16	+	27260156	PANC1	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.05810327806558835	[253]	[268,303,219,140]	0	hSpCas9	negative selection	8246578
20346194	20346217	16	+	27260156	PANC1	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	-0.05024671244100487	[1054]	[809,1055,857,810]	-1	hSpCas9	negative selection	8246579
20346123	20346146	16	+	27260156	PANC1	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.15218733075350876	[869]	[910,812,829,759]	2	hSpCas9	negative selection	8246580
20337419	20337442	16	-	27260156	PANC1	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.4690694556699284	[131]	[213,252,94,91]	7	hSpCas9	negative selection	8310826
20348283	20348306	16	-	27260156	PANC1	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.14191430279319017	[198]	[184,185,239,32]	-2	hSpCas9	negative selection	8310827
20348257	20348280	16	-	27260156	PANC1	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.3628896152760258	[359]	[197,307,295,180]	-5	hSpCas9	negative selection	8310828
20337377	20337400	16	+	27260156	PANC0813	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.30240290707607353	[253]	[320,401,464,283]	5	hSpCas9	negative selection	8367829
20346194	20346217	16	+	27260156	PANC0813	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.31604602281533545	[1054]	[1644,1237,1922,1382]	5	hSpCas9	negative selection	8367830
20346123	20346146	16	+	27260156	PANC0813	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.20427562815683864	[869]	[1246,1100,1306,1065]	3	hSpCas9	negative selection	8367831
20337419	20337442	16	-	27260156	PANC0813	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.35419590518748945	[131]	[247,186,250,115]	6	hSpCas9	negative selection	8432077
20348283	20348306	16	-	27260156	PANC0813	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.30609995726620753	[198]	[177,182,221,172]	-5	hSpCas9	negative selection	8432078
20348257	20348280	16	-	27260156	PANC0813	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.38964015345134584	[359]	[273,383,339,289]	-6	hSpCas9	negative selection	8432079
20337377	20337400	16	+	27260156	RDES	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.08147875121107184	[253]	[281,422,231,274]	1	hSpCas9	negative selection	8489080
20346194	20346217	16	+	27260156	RDES	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.06988223939503158	[1054]	[1170,1062,1284,1631]	1	hSpCas9	negative selection	8489081
20346123	20346146	16	+	27260156	RDES	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.059728138874386216	[869]	[882,826,1229,1301]	1	hSpCas9	negative selection	8489082
20337419	20337442	16	-	27260156	RDES	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.013853476375072171	[131]	[132,125,199,158]	0	hSpCas9	negative selection	8553328
20348283	20348306	16	-	27260156	RDES	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.15838444861489953	[198]	[166,254,191,201]	-3	hSpCas9	negative selection	8553329
20348257	20348280	16	-	27260156	RDES	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.3677363875248003	[359]	[292,297,305,394]	-6	hSpCas9	negative selection	8553330
20337377	20337400	16	+	27260156	PC3	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	-0.013905334676367898	[253]	[159,269,329,288]	0	hSpCas9	negative selection	8610331
20346194	20346217	16	+	27260156	PC3	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	-0.16114154684429516	[1054]	[745,715,1390,1075]	-4	hSpCas9	negative selection	8610332
20346123	20346146	16	+	27260156	PC3	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.061435215297639734	[869]	[525,784,1515,1131]	1	hSpCas9	negative selection	8610333
20337419	20337442	16	-	27260156	PC3	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.17968447235370788	[131]	[120,102,379,75]	4	hSpCas9	negative selection	8674579
20348283	20348306	16	-	27260156	PC3	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	0.25772337938574763	[198]	[153,274,385,199]	5	hSpCas9	negative selection	8674580
20348257	20348280	16	-	27260156	PC3	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.6276987546108939	[359]	[159,83,448,341]	-8	hSpCas9	negative selection	8674581
20337377	20337400	16	+	27260156	PATU8988T	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.19283018470873492	[253]	[211,231,332,344]	3	hSpCas9	negative selection	8731582
20346194	20346217	16	+	27260156	PATU8988T	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.20277578366313898	[1054]	[989,1240,1269,1198]	3	hSpCas9	negative selection	8731583
20346123	20346146	16	+	27260156	PATU8988T	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.1293097172021136	[869]	[620,503,878,1067]	-2	hSpCas9	negative selection	8731584
20337419	20337442	16	-	27260156	PATU8988T	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.46884530318073936	[131]	[85,134,50,101]	-6	hSpCas9	negative selection	8795830
20348283	20348306	16	-	27260156	PATU8988T	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.2708183942070761	[198]	[185,161,53,243]	-4	hSpCas9	negative selection	8795831
20348257	20348280	16	-	27260156	PATU8988T	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.16580931964521373	[359]	[311,390,205,342]	-3	hSpCas9	negative selection	8795832
20337377	20337400	16	+	27260156	T47D	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.3784214460178176	[253]	[385,458,349,335]	7	hSpCas9	negative selection	8852833
20346194	20346217	16	+	27260156	T47D	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.07977352041270858	[1054]	[1339,1266,1197,1397]	1	hSpCas9	negative selection	8852834
20346123	20346146	16	+	27260156	T47D	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.07817150102797255	[869]	[1064,1119,1160,922]	1	hSpCas9	negative selection	8852835
20337419	20337442	16	-	27260156	T47D	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.16263222319521153	[131]	[100,135,110,203]	-4	hSpCas9	negative selection	8917081
20348283	20348306	16	-	27260156	T47D	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.32755089124046277	[198]	[147,164,212,214]	-6	hSpCas9	negative selection	8917082
20348257	20348280	16	-	27260156	T47D	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.4421977061846558	[359]	[368,218,306,348]	-7	hSpCas9	negative selection	8917083
20337377	20337400	16	+	27260156	SU8686	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.22869073294892683	[253]	[309,189,347,352]	4	hSpCas9	negative selection	8974084
20346194	20346217	16	+	27260156	SU8686	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.13334317391277706	[1054]	[1038,939,1165,1538]	2	hSpCas9	negative selection	8974085
20346123	20346146	16	+	27260156	SU8686	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.1691140894535329	[869]	[754,967,1014,1196]	3	hSpCas9	negative selection	8974086
20337419	20337442	16	-	27260156	SU8686	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.3689952314208411	[131]	[183,124,230,134]	6	hSpCas9	negative selection	9038332
20348283	20348306	16	-	27260156	SU8686	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.40171831963075433	[198]	[225,133,105,116]	-6	hSpCas9	negative selection	9038333
20348257	20348280	16	-	27260156	SU8686	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.6294125057074342	[359]	[208,198,218,313]	-7	hSpCas9	negative selection	9038334
20337377	20337400	16	+	27260156	SKES1	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.5267366299028158	[253]	[398,398,345,325]	9	hSpCas9	negative selection	9095335
20346194	20346217	16	+	27260156	SKES1	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.10148220596863089	[1054]	[1337,1190,916,1100]	2	hSpCas9	negative selection	9095336
20346123	20346146	16	+	27260156	SKES1	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.12846502502209767	[869]	[1154,897,1035,741]	3	hSpCas9	negative selection	9095337
20337419	20337442	16	-	27260156	SKES1	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	-0.3563017983284509	[131]	[94,154,72,93]	-7	hSpCas9	negative selection	9159583
20348283	20348306	16	-	27260156	SKES1	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.13932495945984225	[198]	[178,194,178,168]	-3	hSpCas9	negative selection	9159584
20348257	20348280	16	-	27260156	SKES1	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.44658101257659377	[359]	[175,311,349,211]	-7	hSpCas9	negative selection	9159585
20337377	20337400	16	+	27260156	TOV112D	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	-0.019707192236416815	[253]	[227,207,272,280]	0	hSpCas9	negative selection	9216586
20346194	20346217	16	+	27260156	TOV112D	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	-0.19626447719291884	[1054]	[940,1183,871,760]	-4	hSpCas9	negative selection	9216587
20346123	20346146	16	+	27260156	TOV112D	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.046122135086968274	[869]	[742,1084,1026,777]	0	hSpCas9	negative selection	9216588
20337419	20337442	16	-	27260156	TOV112D	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	1.0372485733463215	[131]	[204,204,564,92]	9	hSpCas9	negative selection	9280834
20348283	20348306	16	-	27260156	TOV112D	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.4083634425473517	[198]	[142,88,173,177]	-7	hSpCas9	negative selection	9280835
20348257	20348280	16	-	27260156	TOV112D	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.0728670342810866	[359]	[353,528,285,250]	-1	hSpCas9	negative selection	9280836
20337377	20337400	16	+	27260156	TC71	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.2907024701435156	[253]	[354,398,331,239]	7	hSpCas9	negative selection	9337837
20346194	20346217	16	+	27260156	TC71	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.0022875388103942296	[1054]	[1036,1347,1063,1082]	0	hSpCas9	negative selection	9337838
20346123	20346146	16	+	27260156	TC71	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.029273358148942497	[869]	[1074,732,871,976]	0	hSpCas9	negative selection	9337839
20337419	20337442	16	-	27260156	TC71	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.18425392471624802	[131]	[187,140,179,130]	4	hSpCas9	negative selection	9402085
20348283	20348306	16	-	27260156	TC71	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.23522231010293737	[198]	[214,180,169,156]	-6	hSpCas9	negative selection	9402086
20348257	20348280	16	-	27260156	TC71	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.5277317841446072	[359]	[325,297,172,275]	-9	hSpCas9	negative selection	9402087
20337377	20337400	16	+	27260156	TC32	viability	TCTGGACGGAAAATCGGCCCTGG	UMOD	ENSG00000169344	0.4654534553919034	[253]	[331,190,601,270]	7	hSpCas9	negative selection	9459088
20346194	20346217	16	+	27260156	TC32	viability	TGTCATTGAAGCCCGAGCACCGG	UMOD	ENSG00000169344	0.11366102475983064	[1054]	[996,847,1225,1287]	2	hSpCas9	negative selection	9459089
20346123	20346146	16	+	27260156	TC32	viability	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.06775812657853009	[869]	[734,539,993,948]	-1	hSpCas9	negative selection	9459090
20337419	20337442	16	-	27260156	TC32	viability	TAGAGACTCAACTATCCAAGTGG	UMOD	ENSG00000169344	0.37931835798325686	[131]	[224,132,157,117]	6	hSpCas9	negative selection	9523336
20348283	20348306	16	-	27260156	TC32	viability	TGAGGAGTGCAGTATAGACGAGG	UMOD	ENSG00000169344	-0.44358562063610063	[198]	[127,81,150,209]	-7	hSpCas9	negative selection	9523337
20348257	20348280	16	-	27260156	TC32	viability	GCAAATCGAATAATGGCAGATGG	UMOD	ENSG00000169344	-0.3583875149690431	[359]	[194,168,379,367]	-6	hSpCas9	negative selection	9523338
20344028	20344051	16	-	27869803	HPAFII	viability after 27 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	0.19187540641541423	[103]	[104,26,NaN]	1	hSpCas9	negative selection	9555980
20346123	20346146	16	+	27869803	HPAFII	viability after 27 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.8140435069017461	[234]	[66,72,NaN]	-5	hSpCas9	negative selection	9555981
20348238	20348261	16	-	27869803	HPAFII	viability after 27 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	0.1497013095860058	[206]	[111,127,NaN]	1	hSpCas9	negative selection	9555982
20348974	20348997	16	+	27869803	HPAFII	viability after 27 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	1.1254621806842464	[349]	[503,315,NaN]	8	hSpCas9	negative selection	9555983
20349844	20349867	16	-	27869803	HPAFII	viability after 27 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	1.1200032201147334	[294]	[371,307,NaN]	8	hSpCas9	negative selection	9555984
20350672	20350695	16	+	27869803	HPAFII	viability after 27 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	-0.3491978579763594	[325]	[97,164,NaN]	-3	hSpCas9	negative selection	9555985
20344028	20344051	16	-	27869803	HPAFII	viability after 15 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	-0.6307765897413438	[103]	[94,57,NaN]	-6	hSpCas9	negative selection	9638429
20346123	20346146	16	+	27869803	HPAFII	viability after 15 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.21999754578263697	[234]	[296,166,NaN]	-3	hSpCas9	negative selection	9638430
20348238	20348261	16	-	27869803	HPAFII	viability after 15 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	0.1884108603003867	[206]	[308,218,NaN]	2	hSpCas9	negative selection	9638431
20348974	20348997	16	+	27869803	HPAFII	viability after 15 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.25045594608159016	[349]	[637,328,NaN]	3	hSpCas9	negative selection	9638432
20349844	20349867	16	-	27869803	HPAFII	viability after 15 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	0.6989672679129719	[294]	[407,580,NaN]	7	hSpCas9	negative selection	9638433
20350672	20350695	16	+	27869803	HPAFII	viability after 15 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.10659019244270396	[325]	[494,303,NaN]	1	hSpCas9	negative selection	9638434
20344028	20344051	16	-	27869803	ASPC1	viability after 36 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	-0.4968811029638498	[256]	[3,37,124]	-5	hSpCas9	negative selection	9720878
20346123	20346146	16	+	27869803	ASPC1	viability after 36 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.027689087433720172	[484]	[469,110,10]	0	hSpCas9	negative selection	9720879
20348238	20348261	16	-	27869803	ASPC1	viability after 36 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.10756281083903907	[443]	[125,86,199]	-1	hSpCas9	negative selection	9720880
20348974	20348997	16	+	27869803	ASPC1	viability after 36 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.2345722346334641	[958]	[330,438,397]	2	hSpCas9	negative selection	9720881
20349844	20349867	16	-	27869803	ASPC1	viability after 36 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	-0.02233434384815486	[794]	[368,76,358]	0	hSpCas9	negative selection	9720882
20350672	20350695	16	+	27869803	ASPC1	viability after 36 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.8487580135258075	[783]	[445,480,529]	7	hSpCas9	negative selection	9720883
20344028	20344051	16	-	27869803	PATU8988S	viability after 35 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	0.2606077090721983	[228]	[105,114,NaN]	3	hSpCas9	negative selection	9803327
20346123	20346146	16	+	27869803	PATU8988S	viability after 35 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-0.6468287401525206	[432]	[58,163,NaN]	-6	hSpCas9	negative selection	9803328
20348238	20348261	16	-	27869803	PATU8988S	viability after 35 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	0.4938564192933117	[416]	[237,234,NaN]	5	hSpCas9	negative selection	9803329
20348974	20348997	16	+	27869803	PATU8988S	viability after 35 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.571435582949064	[605]	[223,501,NaN]	6	hSpCas9	negative selection	9803330
20349844	20349867	16	-	27869803	PATU8988S	viability after 35 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	0.7718352977765389	[758]	[496,546,NaN]	7	hSpCas9	negative selection	9803331
20350672	20350695	16	+	27869803	PATU8988S	viability after 35 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.3671537895227647	[763]	[341,451,NaN]	4	hSpCas9	negative selection	9803332
20344028	20344051	16	-	27869803	PATU8988S	viability after 31 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	0.6599800377629137	[228]	[138,150,NaN]	7	hSpCas9	negative selection	9885776
20346123	20346146	16	+	27869803	PATU8988S	viability after 31 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	0.059097126858120796	[432]	[156,208,NaN]	0	hSpCas9	negative selection	9885777
20348238	20348261	16	-	27869803	PATU8988S	viability after 31 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	0.5167902058154706	[416]	[152,345,NaN]	6	hSpCas9	negative selection	9885778
20348974	20348997	16	+	27869803	PATU8988S	viability after 31 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	0.6110007019947243	[605]	[266,498,NaN]	7	hSpCas9	negative selection	9885779
20349844	20349867	16	-	27869803	PATU8988S	viability after 31 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	0.43351600437992677	[758]	[263,592,NaN]	5	hSpCas9	negative selection	9885780
20350672	20350695	16	+	27869803	PATU8988S	viability after 31 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.04821522510961529	[763]	[281,356,NaN]	0	hSpCas9	negative selection	9885781
20344028	20344051	16	-	27869803	HPAFII	viability after 35 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	-0.060760864335863474	[103]	[65,32,NaN]	0	hSpCas9	negative selection	9968225
20346123	20346146	16	+	27869803	HPAFII	viability after 35 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-1.5963612965856153	[234]	[20,59,NaN]	-7	hSpCas9	negative selection	9968226
20348238	20348261	16	-	27869803	HPAFII	viability after 35 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	0.33614584660867985	[206]	[120,144,NaN]	2	hSpCas9	negative selection	9968227
20348974	20348997	16	+	27869803	HPAFII	viability after 35 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	1.4035188672490264	[349]	[416,526,NaN]	8	hSpCas9	negative selection	9968228
20349844	20349867	16	-	27869803	HPAFII	viability after 35 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	0.8136149879382211	[294]	[293,226,NaN]	5	hSpCas9	negative selection	9968229
20350672	20350695	16	+	27869803	HPAFII	viability after 35 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.12973659913337976	[325]	[133,232,NaN]	0	hSpCas9	negative selection	9968230
20344028	20344051	16	-	27869803	HPAFII	viability after 31 days	GAAGACCGCCCTACAGCCAATGG	UMOD	ENSG00000169344	-0.3256952862923608	[103]	[36,56,NaN]	-2	hSpCas9	negative selection	10050674
20346123	20346146	16	+	27869803	HPAFII	viability after 31 days	TACCGTCAACACTGTCCCACAGG	UMOD	ENSG00000169344	-1.4406854731268663	[234]	[16,82,NaN]	-7	hSpCas9	negative selection	10050675
20348238	20348261	16	-	27869803	HPAFII	viability after 31 days	ATGGCACTGCCAGTGCAAACAGG	UMOD	ENSG00000169344	-0.10379772005415833	[206]	[76,141,NaN]	0	hSpCas9	negative selection	10050676
20348974	20348997	16	+	27869803	HPAFII	viability after 31 days	CACGTCTGTGCAGCCGAGACCGG	UMOD	ENSG00000169344	1.1768776445825515	[349]	[434,453,NaN]	8	hSpCas9	negative selection	10050677
20349844	20349867	16	-	27869803	HPAFII	viability after 31 days	CAAAGTACAACTGCCCAGCCAGG	UMOD	ENSG00000169344	1.0544655598429469	[294]	[362,322,NaN]	7	hSpCas9	negative selection	10050678
20350672	20350695	16	+	27869803	HPAFII	viability after 31 days	TGCAGTTGTGATGAACCAAGAGG	UMOD	ENSG00000169344	0.079713999639625	[325]	[189,196,NaN]	0	hSpCas9	negative selection	10050679
20348727	20348750	16	-	28162770	P31FUJ	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	0.0344816744207731	[112]	[135]	0	hSpCas9	negative selection	10261395
20349007	20349030	16	+	28162770	P31FUJ	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	0.963498212452231	[270]	[620]	9	hSpCas9	negative selection	10261396
20346148	20346171	16	-	28162770	P31FUJ	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	-0.16221023658432487	[338]	[355]	-1	hSpCas9	negative selection	10261397
20349171	20349194	16	-	28162770	P31FUJ	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.6279919766046859	[211]	[384]	7	hSpCas9	negative selection	10261398
20348807	20348830	16	-	28162770	P31FUJ	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	0.09108740680626992	[293]	[367]	0	hSpCas9	negative selection	10261399
20348632	20348655	16	+	28162770	P31FUJ	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	0.16034268901562299	[82]	[108]	1	hSpCas9	negative selection	10261400
20346239	20346262	16	-	28162770	P31FUJ	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	0.17283659686221564	[76]	[101]	1	hSpCas9	negative selection	10261401
20350698	20350721	16	-	28162770	P31FUJ	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.42010829946544304	[628]	[988]	5	hSpCas9	negative selection	10261402
20349094	20349117	16	+	28162770	P31FUJ	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	-0.15015831026223725	[440]	[466]	-1	hSpCas9	negative selection	10261403
20349070	20349093	16	+	28162770	P31FUJ	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	0.1805836689933067	[436]	[581]	2	hSpCas9	negative selection	10261404
20348727	20348750	16	-	28162770	TF1	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	NaN	[NaN]	[107]	1	hSpCas9	negative selection	10430761
20349007	20349030	16	+	28162770	TF1	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	NaN	[NaN]	[455]	1	hSpCas9	negative selection	10430762
20346148	20346171	16	-	28162770	TF1	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	NaN	[NaN]	[203]	1	hSpCas9	negative selection	10430763
20349171	20349194	16	-	28162770	TF1	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	NaN	[NaN]	[284]	1	hSpCas9	negative selection	10430764
20348807	20348830	16	-	28162770	TF1	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	NaN	[NaN]	[362]	1	hSpCas9	negative selection	10430765
20348632	20348655	16	+	28162770	TF1	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10430766
20346239	20346262	16	-	28162770	TF1	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10430767
20350698	20350721	16	-	28162770	TF1	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	NaN	[NaN]	[733]	1	hSpCas9	negative selection	10430768
20349094	20349117	16	+	28162770	TF1	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	NaN	[NaN]	[333]	1	hSpCas9	negative selection	10430769
20349070	20349093	16	+	28162770	TF1	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	NaN	[NaN]	[289]	1	hSpCas9	negative selection	10430770
20348727	20348750	16	-	28162770	SKM1	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	0.13617812628336745	[34]	[67]	1	hSpCas9	negative selection	10600127
20349007	20349030	16	+	28162770	SKM1	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	0.28652275875616373	[63]	[137]	3	hSpCas9	negative selection	10600128
20346148	20346171	16	-	28162770	SKM1	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	0.8387922156587966	[104]	[331]	7	hSpCas9	negative selection	10600129
20349171	20349194	16	-	28162770	SKM1	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.11659775731385125	[83]	[160]	1	hSpCas9	negative selection	10600130
20348807	20348830	16	-	28162770	SKM1	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	-0.10493566129350418	[72]	[119]	-1	hSpCas9	negative selection	10600131
20348632	20348655	16	+	28162770	SKM1	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	0.2711077063694761	[29]	[63]	2	hSpCas9	negative selection	10600132
20346239	20346262	16	-	28162770	SKM1	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	-0.13394570433674602	[17]	[28]	-1	hSpCas9	negative selection	10600133
20350698	20350721	16	-	28162770	SKM1	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.21818739209369342	[176]	[363]	2	hSpCas9	negative selection	10600134
20349094	20349117	16	+	28162770	SKM1	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	-0.39976869733895776	[99]	[133]	-3	hSpCas9	negative selection	10600135
20349070	20349093	16	+	28162770	SKM1	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	0.3849606827448365	[93]	[216]	4	hSpCas9	negative selection	10600136
20348727	20348750	16	-	28162770	SKM1	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	0.13617812628336745	[34]	[67]	1	hSpCas9	negative selection	10769493
20349007	20349030	16	+	28162770	SKM1	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	0.28652275875616373	[63]	[137]	3	hSpCas9	negative selection	10769494
20346148	20346171	16	-	28162770	SKM1	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	0.8387922156587966	[104]	[331]	7	hSpCas9	negative selection	10769495
20349171	20349194	16	-	28162770	SKM1	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.11659775731385125	[83]	[160]	1	hSpCas9	negative selection	10769496
20348807	20348830	16	-	28162770	SKM1	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	-0.10493566129350418	[72]	[119]	-1	hSpCas9	negative selection	10769497
20348632	20348655	16	+	28162770	SKM1	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	0.2711077063694761	[29]	[63]	2	hSpCas9	negative selection	10769498
20346239	20346262	16	-	28162770	SKM1	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	-0.13394570433674602	[17]	[28]	-1	hSpCas9	negative selection	10769499
20350698	20350721	16	-	28162770	SKM1	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.21818739209369342	[176]	[363]	2	hSpCas9	negative selection	10769500
20349094	20349117	16	+	28162770	SKM1	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	-0.39976869733895776	[99]	[133]	-3	hSpCas9	negative selection	10769501
20349070	20349093	16	+	28162770	SKM1	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	0.3849606827448365	[93]	[216]	4	hSpCas9	negative selection	10769502
20348727	20348750	16	-	28162770	PL21	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	0.7390057006210223	[105]	[76]	6	hSpCas9	negative selection	10938859
20349007	20349030	16	+	28162770	PL21	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	-0.8172076290745764	[250]	[61]	-5	hSpCas9	negative selection	10938860
20346148	20346171	16	-	28162770	PL21	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	0.58686283217375	[282]	[184]	5	hSpCas9	negative selection	10938861
20349171	20349194	16	-	28162770	PL21	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.7472806497755089	[218]	[159]	6	hSpCas9	negative selection	10938862
20348807	20348830	16	-	28162770	PL21	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	0.5164431601828041	[256]	[159]	4	hSpCas9	negative selection	10938863
20348632	20348655	16	+	28162770	PL21	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	-0.6072153075682841	[97]	[27]	-4	hSpCas9	negative selection	10938864
20346239	20346262	16	-	28162770	PL21	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	-0.23595950031735313	[45]	[16]	-2	hSpCas9	negative selection	10938865
20350698	20350721	16	-	28162770	PL21	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.07970183616765025	[436]	[200]	0	hSpCas9	negative selection	10938866
20349094	20349117	16	+	28162770	PL21	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	-0.06751141941484373	[312]	[129]	0	hSpCas9	negative selection	10938867
20349070	20349093	16	+	28162770	PL21	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	0.054288748025865474	[311]	[140]	0	hSpCas9	negative selection	10938868
20348727	20348750	16	-	28162770	P31FUJ	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	0.0344816744207731	[112]	[135]	0	hSpCas9	negative selection	11108225
20349007	20349030	16	+	28162770	P31FUJ	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	0.963498212452231	[270]	[620]	9	hSpCas9	negative selection	11108226
20346148	20346171	16	-	28162770	P31FUJ	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	-0.16221023658432487	[338]	[355]	-1	hSpCas9	negative selection	11108227
20349171	20349194	16	-	28162770	P31FUJ	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.6279919766046859	[211]	[384]	7	hSpCas9	negative selection	11108228
20348807	20348830	16	-	28162770	P31FUJ	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	0.09108740680626992	[293]	[367]	0	hSpCas9	negative selection	11108229
20348632	20348655	16	+	28162770	P31FUJ	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	0.16034268901562299	[82]	[108]	1	hSpCas9	negative selection	11108230
20346239	20346262	16	-	28162770	P31FUJ	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	0.17283659686221564	[76]	[101]	1	hSpCas9	negative selection	11108231
20350698	20350721	16	-	28162770	P31FUJ	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.42010829946544304	[628]	[988]	5	hSpCas9	negative selection	11108232
20349094	20349117	16	+	28162770	P31FUJ	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	-0.15015831026223725	[440]	[466]	-1	hSpCas9	negative selection	11108233
20349070	20349093	16	+	28162770	P31FUJ	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	0.1805836689933067	[436]	[581]	2	hSpCas9	negative selection	11108234
20348727	20348750	16	-	28162770	OCIAML5	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	0.6799470499082002	[36]	[106]	6	hSpCas9	negative selection	11277591
20349007	20349030	16	+	28162770	OCIAML5	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	0.22555432625847693	[198]	[419]	1	hSpCas9	negative selection	11277592
20346148	20346171	16	-	28162770	OCIAML5	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	0.570876126500193	[181]	[487]	5	hSpCas9	negative selection	11277593
20349171	20349194	16	-	28162770	OCIAML5	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	1.4481664529240463	[66]	[329]	9	hSpCas9	negative selection	11277594
20348807	20348830	16	-	28162770	OCIAML5	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	-0.28193148782048016	[162]	[241]	-2	hSpCas9	negative selection	11277595
20348632	20348655	16	+	28162770	OCIAML5	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	-0.13324832340805015	[47]	[78]	-1	hSpCas9	negative selection	11277596
20346239	20346262	16	-	28162770	OCIAML5	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	-0.24507776381284185	[64]	[98]	-2	hSpCas9	negative selection	11277597
20350698	20350721	16	-	28162770	OCIAML5	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.13033936912126465	[329]	[651]	1	hSpCas9	negative selection	11277598
20349094	20349117	16	+	28162770	OCIAML5	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	0.2748455416182227	[260]	[569]	2	hSpCas9	negative selection	11277599
20349070	20349093	16	+	28162770	OCIAML5	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	0.8619758790220887	[202]	[665]	7	hSpCas9	negative selection	11277600
20348727	20348750	16	-	28162770	EOL1	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	-0.7436086646770201	[231]	[72]	-5	hSpCas9	negative selection	11446957
20349007	20349030	16	+	28162770	EOL1	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	-0.4203636413176671	[347]	[136]	-3	hSpCas9	negative selection	11446958
20346148	20346171	16	-	28162770	EOL1	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	0.3366911975801987	[498]	[331]	3	hSpCas9	negative selection	11446959
20349171	20349194	16	-	28162770	EOL1	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.6103199353647545	[326]	[262]	5	hSpCas9	negative selection	11446960
20348807	20348830	16	-	28162770	EOL1	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	-0.16960972225381316	[458]	[214]	-1	hSpCas9	negative selection	11446961
20348632	20348655	16	+	28162770	EOL1	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	0.9419298497987709	[164]	[166]	7	hSpCas9	negative selection	11446962
20346239	20346262	16	-	28162770	EOL1	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	0.8465452595692613	[75]	[71]	7	hSpCas9	negative selection	11446963
20350698	20350721	16	-	28162770	EOL1	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.8111419041702936	[753]	[696]	7	hSpCas9	negative selection	11446964
20349094	20349117	16	+	28162770	EOL1	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	0.9434893352239949	[453]	[459]	7	hSpCas9	negative selection	11446965
20349070	20349093	16	+	28162770	EOL1	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	1.0671018014967075	[336]	[371]	8	hSpCas9	negative selection	11446966
20348727	20348750	16	-	28162770	MOLM13	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	1.2898910795665843	[167]	[296]	8	hSpCas9	negative selection	11616323
20349007	20349030	16	+	28162770	MOLM13	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	0.5122835009030322	[383]	[395]	4	hSpCas9	negative selection	11616324
20346148	20346171	16	-	28162770	MOLM13	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	1.5860222739728234	[333]	[724]	9	hSpCas9	negative selection	11616325
20349171	20349194	16	-	28162770	MOLM13	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	-0.16808840503680061	[330]	[212]	-1	hSpCas9	negative selection	11616326
20348807	20348830	16	-	28162770	MOLM13	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	1.4347225176093796	[351]	[687]	9	hSpCas9	negative selection	11616327
20348632	20348655	16	+	28162770	MOLM13	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	0.3694856774835842	[90]	[84]	2	hSpCas9	negative selection	11616328
20346239	20346262	16	-	28162770	MOLM13	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	-0.7020356198977336	[62]	[27]	-4	hSpCas9	negative selection	11616329
20350698	20350721	16	-	28162770	MOLM13	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.6302076732535782	[654]	[732]	5	hSpCas9	negative selection	11616330
20349094	20349117	16	+	28162770	MOLM13	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	-0.049686279446702786	[480]	[335]	0	hSpCas9	negative selection	11616331
20349070	20349093	16	+	28162770	MOLM13	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	0.330385857794644	[406]	[369]	2	hSpCas9	negative selection	11616332
20348727	20348750	16	-	28162770	HEL	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	0.5801973659316441	[164]	[157]	5	hSpCas9	negative selection	11785689
20349007	20349030	16	+	28162770	HEL	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	0.5543298577785917	[285]	[268]	5	hSpCas9	negative selection	11785690
20346148	20346171	16	-	28162770	HEL	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	0.0449522909216169	[338]	[223]	0	hSpCas9	negative selection	11785691
20349171	20349194	16	-	28162770	HEL	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.4708523142247585	[275]	[244]	4	hSpCas9	negative selection	11785692
20348807	20348830	16	-	28162770	HEL	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	0.8430374824861879	[328]	[377]	7	hSpCas9	negative selection	11785693
20348632	20348655	16	+	28162770	HEL	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	0.10508204605755733	[134]	[92]	0	hSpCas9	negative selection	11785694
20346239	20346262	16	-	28162770	HEL	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	0.5630116395296229	[92]	[87]	5	hSpCas9	negative selection	11785695
20350698	20350721	16	-	28162770	HEL	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.4770608016582305	[635]	[566]	4	hSpCas9	negative selection	11785696
20349094	20349117	16	+	28162770	HEL	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	-0.21975764424970823	[419]	[230]	-1	hSpCas9	negative selection	11785697
20349070	20349093	16	+	28162770	HEL	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	0.19527985502913559	[374]	[274]	1	hSpCas9	negative selection	11785698
20348727	20348750	16	-	28162770	MV411	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	0.3983042164094031	[126]	[140]	3	hSpCas9	negative selection	11955055
20349007	20349030	16	+	28162770	MV411	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	0.30017901285474846	[187]	[194]	2	hSpCas9	negative selection	11955056
20346148	20346171	16	-	28162770	MV411	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	0.06856359261297995	[282]	[249]	0	hSpCas9	negative selection	11955057
20349171	20349194	16	-	28162770	MV411	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.1866123580867318	[217]	[208]	1	hSpCas9	negative selection	11955058
20348807	20348830	16	-	28162770	MV411	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	0.9879609643621705	[242]	[405]	8	hSpCas9	negative selection	11955059
20348632	20348655	16	+	28162770	MV411	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	0.15122223552347214	[92]	[86]	1	hSpCas9	negative selection	11955060
20346239	20346262	16	-	28162770	MV411	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	0.3185206488442581	[98]	[103]	3	hSpCas9	negative selection	11955061
20350698	20350721	16	-	28162770	MV411	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.32415251692358815	[530]	[559]	3	hSpCas9	negative selection	11955062
20349094	20349117	16	+	28162770	MV411	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	0.33778405287902935	[293]	[312]	3	hSpCas9	negative selection	11955063
20349070	20349093	16	+	28162770	MV411	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	-0.20678473205691228	[310]	[226]	-1	hSpCas9	negative selection	11955064
20348727	20348750	16	-	28162770	MONOMAC1	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	-0.7185739676390763	[88]	[61]	-5	hSpCas9	negative selection	12124421
20349007	20349030	16	+	28162770	MONOMAC1	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	0.35706468995684193	[125]	[184]	3	hSpCas9	negative selection	12124422
20346148	20346171	16	-	28162770	MONOMAC1	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	0.17414636262986272	[166]	[215]	1	hSpCas9	negative selection	12124423
20349171	20349194	16	-	28162770	MONOMAC1	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.29001189713467834	[126]	[177]	3	hSpCas9	negative selection	12124424
20348807	20348830	16	-	28162770	MONOMAC1	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	-0.5243314516967315	[201]	[160]	-4	hSpCas9	negative selection	12124425
20348632	20348655	16	+	28162770	MONOMAC1	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	0.7590198053528494	[49]	[96]	7	hSpCas9	negative selection	12124426
20346239	20346262	16	-	28162770	MONOMAC1	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	-0.4600712528933477	[29]	[24]	-4	hSpCas9	negative selection	12124427
20350698	20350721	16	-	28162770	MONOMAC1	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.47886722137037374	[332]	[531]	5	hSpCas9	negative selection	12124428
20349094	20349117	16	+	28162770	MONOMAC1	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	-0.08097871759597708	[190]	[206]	0	hSpCas9	negative selection	12124429
20349070	20349093	16	+	28162770	MONOMAC1	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	0.4556922099386208	[200]	[315]	4	hSpCas9	negative selection	12124430
20348727	20348750	16	-	28162770	OCIAML2	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	0.1334414984266995	[24]	[151]	1	hSpCas9	negative selection	12293787
20349007	20349030	16	+	28162770	OCIAML2	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	0.7257673875613423	[41]	[384]	7	hSpCas9	negative selection	12293788
20346148	20346171	16	-	28162770	OCIAML2	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	0.24337462048073388	[56]	[373]	2	hSpCas9	negative selection	12293789
20349171	20349194	16	-	28162770	OCIAML2	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.4479425754139926	[40]	[309]	4	hSpCas9	negative selection	12293790
20348807	20348830	16	-	28162770	OCIAML2	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	0.5476555277855882	[48]	[396]	5	hSpCas9	negative selection	12293791
20348632	20348655	16	+	28162770	OCIAML2	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	0.4241879380657825	[15]	[118]	4	hSpCas9	negative selection	12293792
20346239	20346262	16	-	28162770	OCIAML2	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	0.16680009537313056	[8]	[55]	1	hSpCas9	negative selection	12293793
20350698	20350721	16	-	28162770	OCIAML2	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.47055394792023497	[96]	[744]	4	hSpCas9	negative selection	12293794
20349094	20349117	16	+	28162770	OCIAML2	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	0.48272008145901757	[54]	[425]	5	hSpCas9	negative selection	12293795
20349070	20349093	16	+	28162770	OCIAML2	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	0.9060907424855807	[61]	[643]	8	hSpCas9	negative selection	12293796
20348727	20348750	16	-	28162770	OCIAML3	viability	GCGCAGCACCGAGTACGGGGAGG	UMOD	ENSG00000169344	0.7508208566732778	[24]	[126]	6	hSpCas9	negative selection	12463153
20349007	20349030	16	+	28162770	OCIAML3	viability	GAAGCCTTCGGGGCAGACGCAGG	UMOD	ENSG00000169344	-0.1414954356266564	[75]	[207]	-1	hSpCas9	negative selection	12463154
20346148	20346171	16	-	28162770	OCIAML3	viability	GTAGTGACCCCAGCCCGGGATGG	UMOD	ENSG00000169344	0.37603913757420915	[72]	[285]	3	hSpCas9	negative selection	12463155
20349171	20349194	16	-	28162770	OCIAML3	viability	CAGCAATGCCACCTGCACGGAGG	UMOD	ENSG00000169344	0.9517842631163154	[55]	[326]	8	hSpCas9	negative selection	12463156
20348807	20348830	16	-	28162770	OCIAML3	viability	GGGTTGGACTGCGTGCCCGAGGG	UMOD	ENSG00000169344	1.2976161986310448	[56]	[422]	9	hSpCas9	negative selection	12463157
20348632	20348655	16	+	28162770	OCIAML3	viability	GCAGCGCAGGACTGGCACGCAGG	UMOD	ENSG00000169344	0.6470004591796318	[32]	[155]	6	hSpCas9	negative selection	12463158
20346239	20346262	16	-	28162770	OCIAML3	viability	GAAGAGTCTGGGCTTCGACAAGG	UMOD	ENSG00000169344	0.5936193628516081	[17]	[81]	5	hSpCas9	negative selection	12463159
20350698	20350721	16	-	28162770	OCIAML3	viability	GACTTGGATGCTGATGGTGGTGG	UMOD	ENSG00000169344	0.83422935670954	[135]	[731]	7	hSpCas9	negative selection	12463160
20349094	20349117	16	+	28162770	OCIAML3	viability	GCACTCATCCAGGTCCACGCAGG	UMOD	ENSG00000169344	0.15828368507087942	[102]	[346]	1	hSpCas9	negative selection	12463161
20349070	20349093	16	+	28162770	OCIAML3	viability	GCAGTTGTGAGCTCCAGGAATGG	UMOD	ENSG00000169344	-0.2252257320061919	[102]	[265]	-2	hSpCas9	negative selection	12463162