Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:23326
• Symbol:USP22
• Description:ubiquitin specific peptidase 22

DataSource: http://genomecrispr.dkfz.de/#!/results/USP22

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
21028560	21028583	17	-	26472758	Jiyoye	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-0.05848819084293844	[28]	[20]	0	hSpCas9	negative selection	178382
21007873	21007896	17	+	26472758	Jiyoye	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	0.01231576416466007	[70]	[53]	0	hSpCas9	negative selection	178383
21042810	21042833	17	-	26472758	Jiyoye	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	1.2799401932097654	[76]	[140]	7	hSpCas9	negative selection	178384
21042742	21042765	17	-	26472758	Jiyoye	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-0.5475953645011288	[156]	[80]	-4	hSpCas9	negative selection	178385
21042719	21042742	17	-	26472758	Jiyoye	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	-0.1679393332589355	[72]	[48]	-1	hSpCas9	negative selection	178386
21021205	21021228	17	-	26472758	Jiyoye	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.6059552456203707	[175]	[201]	4	hSpCas9	negative selection	178387
21017941	21017964	17	-	26472758	Jiyoye	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.3207450730573256	[52]	[31]	-2	hSpCas9	negative selection	178388
21011279	21011302	17	+	26472758	Jiyoye	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	178389
21011239	21011262	17	+	26472758	Jiyoye	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	3.9921378822270293	[0]	[11]	9	hSpCas9	negative selection	178390
21011228	21011251	17	+	26472758	Jiyoye	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-3.547020928881002	[30]	[1]	-9	hSpCas9	negative selection	178391
21028560	21028583	17	-	26472758	KBM7	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-1.5601583911517665	[238,271]	[8,69]	-8	hSpCas9	negative selection	369500
21007873	21007896	17	+	26472758	KBM7	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	-0.42183449085907126	[411,435]	[74,216]	-4	hSpCas9	negative selection	369501
21042810	21042833	17	-	26472758	KBM7	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	0.31634437800916304	[653,431]	[391,241]	3	hSpCas9	negative selection	369502
21042742	21042765	17	-	26472758	KBM7	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-0.48448604121496264	[730,597]	[285,164]	-4	hSpCas9	negative selection	369503
21042719	21042742	17	-	26472758	KBM7	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	-0.6620768340257696	[670,354]	[112,179]	-5	hSpCas9	negative selection	369504
21021205	21021228	17	-	26472758	KBM7	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	-1.3536901263894319	[1001,645]	[186,114]	-7	hSpCas9	negative selection	369505
21017941	21017964	17	-	26472758	KBM7	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.17344596203375584	[247,305]	[92,138]	-2	hSpCas9	negative selection	369506
21011279	21011302	17	+	26472758	KBM7	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	-1.3789537513076375	[16,14]	[4,0]	-7	hSpCas9	negative selection	369507
21011239	21011262	17	+	26472758	KBM7	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	0.23571309477984803	[59,12]	[9,26]	2	hSpCas9	negative selection	369508
21011228	21011251	17	+	26472758	KBM7	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-0.5345285909282476	[31,10]	[12,0]	-5	hSpCas9	negative selection	369509
21028560	21028583	17	-	26472758	Raji	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	0.5053475212935016	[84]	[27]	5	hSpCas9	negative selection	560618
21007873	21007896	17	+	26472758	Raji	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	0.5674084894257534	[220]	[75]	5	hSpCas9	negative selection	560619
21042810	21042833	17	-	26472758	Raji	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	0.09681429366341204	[273]	[67]	0	hSpCas9	negative selection	560620
21042742	21042765	17	-	26472758	Raji	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	0.11303009851474156	[254]	[63]	1	hSpCas9	negative selection	560621
21042719	21042742	17	-	26472758	Raji	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	0.926520687446399	[330]	[145]	8	hSpCas9	negative selection	560622
21021205	21021228	17	-	26472758	Raji	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.4520317067610452	[377]	[119]	4	hSpCas9	negative selection	560623
21017941	21017964	17	-	26472758	Raji	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	0.04848984632003084	[124]	[29]	0	hSpCas9	negative selection	560624
21011279	21011302	17	+	26472758	Raji	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	0.1898456955655723	[33]	[8]	1	hSpCas9	negative selection	560625
21011239	21011262	17	+	26472758	Raji	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	0.03699420748220161	[20]	[4]	0	hSpCas9	negative selection	560626
21011228	21011251	17	+	26472758	Raji	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-3.5650418065978964	[50]	[0]	-9	hSpCas9	negative selection	560627
21028560	21028583	17	-	26472758	K562	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-0.9998884700984415	[198]	[83]	-5	hSpCas9	negative selection	751736
21007873	21007896	17	+	26472758	K562	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	-0.7555812723335532	[327]	[163]	-4	hSpCas9	negative selection	751737
21042810	21042833	17	-	26472758	K562	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	0.685193788358899	[374]	[508]	5	hSpCas9	negative selection	751738
21042742	21042765	17	-	26472758	K562	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-2.2834626778474423	[668]	[115]	-8	hSpCas9	negative selection	751739
21042719	21042742	17	-	26472758	K562	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	-1.0006937701700847	[383]	[161]	-5	hSpCas9	negative selection	751740
21021205	21021228	17	-	26472758	K562	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	-0.8440914421532197	[688]	[323]	-5	hSpCas9	negative selection	751741
21017941	21017964	17	-	26472758	K562	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-2.314312231481529	[217]	[36]	-8	hSpCas9	negative selection	751742
21011279	21011302	17	+	26472758	K562	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	-2.0775093672209155	[39]	[7]	-7	hSpCas9	negative selection	751743
21011239	21011262	17	+	26472758	K562	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	-4.613562267461124	[28]	[0]	-9	hSpCas9	negative selection	751744
21011228	21011251	17	+	26472758	K562	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-4.925506273775865	[35]	[0]	-9	hSpCas9	negative selection	751745
21015848	21015871	17	-	26627737	DLD1	viability	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	0.876478400764285	[741]	[549,605,168]	8	hSpCas9	negative selection	796541
21017941	21017964	17	-	26627737	DLD1	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-1.7682429796338548	[199]	[8,1,39]	-8	hSpCas9	negative selection	796542
21019112	21019135	17	-	26627737	DLD1	viability	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.7094323189274336	[521]	[288,217,287]	7	hSpCas9	negative selection	796543
21021140	21021163	17	-	26627737	DLD1	viability	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.7921852934715133	[431]	[134,68,35]	-6	hSpCas9	negative selection	796544
21028630	21028653	17	-	26627737	DLD1	viability	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	-0.07211234759798268	[730]	[294,208,156]	0	hSpCas9	negative selection	796545
21043609	21043632	17	-	26627737	DLD1	viability	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	-1.0607902408472438	[908]	[102,198,112]	-7	hSpCas9	negative selection	796546
21015848	21015871	17	-	26627737	GBM cells	viability after 5 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	0.18878989293812054	[354]	[211,221]	3	hSpCas9	negative selection	878856
21017941	21017964	17	-	26627737	GBM cells	viability after 5 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.3548427173600974	[92]	[22,54]	-5	hSpCas9	negative selection	878857
21019112	21019135	17	-	26627737	GBM cells	viability after 5 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.9713558875543249	[300]	[326,305]	9	hSpCas9	negative selection	878858
21021140	21021163	17	-	26627737	GBM cells	viability after 5 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.43340582584827264	[417]	[151,179]	-6	hSpCas9	negative selection	878859
21028630	21028653	17	-	26627737	GBM cells	viability after 5 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	-0.046952687980835905	[339]	[204,147]	0	hSpCas9	negative selection	878860
21043609	21043632	17	-	26627737	GBM cells	viability after 5 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	-0.11135446056814169	[281]	[115,163]	-2	hSpCas9	negative selection	878861
21015848	21015871	17	-	26627737	GBM cells	viability after 13 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	0.5607725416591992	[354]	[314,258]	7	hSpCas9	negative selection	961171
21017941	21017964	17	-	26627737	GBM cells	viability after 13 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.31380464298798394	[92]	[60,23]	-4	hSpCas9	negative selection	961172
21019112	21019135	17	-	26627737	GBM cells	viability after 13 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.9311630850638046	[300]	[381,253]	9	hSpCas9	negative selection	961173
21021140	21021163	17	-	26627737	GBM cells	viability after 13 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.25567958644055216	[417]	[259,132]	-3	hSpCas9	negative selection	961174
21028630	21028653	17	-	26627737	GBM cells	viability after 13 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	-0.3432876259052191	[339]	[215,87]	-4	hSpCas9	negative selection	961175
21043609	21043632	17	-	26627737	GBM cells	viability after 13 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	0.06653371345609785	[281]	[130,183]	0	hSpCas9	negative selection	961176
21015848	21015871	17	-	26627737	GBM cells	viability after 21 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	0.41897740405730943	[354]	[272,243]	4	hSpCas9	negative selection	1043486
21017941	21017964	17	-	26627737	GBM cells	viability after 21 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.8561578589304206	[92]	[29,25]	-6	hSpCas9	negative selection	1043487
21019112	21019135	17	-	26627737	GBM cells	viability after 21 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.8892584682188536	[300]	[328,278]	8	hSpCas9	negative selection	1043488
21021140	21021163	17	-	26627737	GBM cells	viability after 21 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	0.009345378792121717	[417]	[226,229]	0	hSpCas9	negative selection	1043489
21028630	21028653	17	-	26627737	GBM cells	viability after 21 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	-0.36760581610473586	[339]	[150,135]	-3	hSpCas9	negative selection	1043490
21043609	21043632	17	-	26627737	GBM cells	viability after 21 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	0.4486545352614454	[281]	[206,210]	4	hSpCas9	negative selection	1043491
21015848	21015871	17	-	26627737	RPE1	viability after 9 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	0.13449284408194484	[1495]	[352,721]	1	hSpCas9	negative selection	1125801
21017941	21017964	17	-	26627737	RPE1	viability after 9 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	0.6581804230593629	[102]	[25,82]	4	hSpCas9	negative selection	1125802
21019112	21019135	17	-	26627737	RPE1	viability after 9 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.7149811780082332	[873]	[301,638]	5	hSpCas9	negative selection	1125803
21021140	21021163	17	-	26627737	RPE1	viability after 9 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	0.565211054592052	[582]	[235,313]	4	hSpCas9	negative selection	1125804
21028630	21028653	17	-	26627737	RPE1	viability after 9 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	0.16246314514626703	[937]	[160,544]	1	hSpCas9	negative selection	1125805
21043609	21043632	17	-	26627737	RPE1	viability after 9 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	-1.5532604757616264	[1318]	[148,129]	-8	hSpCas9	negative selection	1125806
21015848	21015871	17	-	26627737	RPE1	viability after 12 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	0.005692892050449094	[1495]	[352,456]	0	hSpCas9	negative selection	1208116
21017941	21017964	17	-	26627737	RPE1	viability after 12 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-1.243715099513298	[102]	[0,22]	-7	hSpCas9	negative selection	1208117
21019112	21019135	17	-	26627737	RPE1	viability after 12 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.938311530796391	[873]	[363,540]	6	hSpCas9	negative selection	1208118
21021140	21021163	17	-	26627737	RPE1	viability after 12 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	0.4186801096246188	[582]	[255,159]	3	hSpCas9	negative selection	1208119
21028630	21028653	17	-	26627737	RPE1	viability after 12 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	-0.24824611793246465	[937]	[166,259]	-2	hSpCas9	negative selection	1208120
21043609	21043632	17	-	26627737	RPE1	viability after 12 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	-0.425660437474007	[1318]	[206,323]	-3	hSpCas9	negative selection	1208121
21015848	21015871	17	-	26627737	RPE1	viability after 15 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.5330090064077684	[1495]	[237,344]	-3	hSpCas9	negative selection	1290431
21017941	21017964	17	-	26627737	RPE1	viability after 15 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.6703736081444727	[102]	[0,34]	-4	hSpCas9	negative selection	1290432
21019112	21019135	17	-	26627737	RPE1	viability after 15 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.9260817122590552	[873]	[369,565]	5	hSpCas9	negative selection	1290433
21021140	21021163	17	-	26627737	RPE1	viability after 15 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	0.7752670458305995	[582]	[323,241]	5	hSpCas9	negative selection	1290434
21028630	21028653	17	-	26627737	RPE1	viability after 15 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	0.08202234890316634	[937]	[147,408]	0	hSpCas9	negative selection	1290435
21043609	21043632	17	-	26627737	RPE1	viability after 15 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	-0.8071775368403306	[1318]	[199,225]	-5	hSpCas9	negative selection	1290436
21015848	21015871	17	-	26627737	RPE1	viability after 18 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.4798893272415757	[1495]	[186,398]	-3	hSpCas9	negative selection	1372746
21017941	21017964	17	-	26627737	RPE1	viability after 18 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	0.2247990207295132	[102]	[31,32]	1	hSpCas9	negative selection	1372747
21019112	21019135	17	-	26627737	RPE1	viability after 18 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.9088168157763394	[873]	[408,478]	5	hSpCas9	negative selection	1372748
21021140	21021163	17	-	26627737	RPE1	viability after 18 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	0.8340878296195069	[582]	[279,280]	5	hSpCas9	negative selection	1372749
21028630	21028653	17	-	26627737	RPE1	viability after 18 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	0.263499259920277	[937]	[226,385]	1	hSpCas9	negative selection	1372750
21043609	21043632	17	-	26627737	RPE1	viability after 18 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	-0.7761073741645679	[1318]	[159,258]	-5	hSpCas9	negative selection	1372751
21015848	21015871	17	-	26627737	HeLa	viability after 8 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.3972927324966734	[876]	[439,152,307]	-4	hSpCas9	negative selection	1455061
21017941	21017964	17	-	26627737	HeLa	viability after 8 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	0.5272845589781245	[92]	[82,47,49]	5	hSpCas9	negative selection	1455062
21019112	21019135	17	-	26627737	HeLa	viability after 8 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.42872039924533456	[461]	[398,228,215]	4	hSpCas9	negative selection	1455063
21021140	21021163	17	-	26627737	HeLa	viability after 8 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.38439740840462877	[706]	[433,129,189]	-4	hSpCas9	negative selection	1455064
21028630	21028653	17	-	26627737	HeLa	viability after 8 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	-0.04390319205692372	[761]	[306,322,330]	0	hSpCas9	negative selection	1455065
21043609	21043632	17	-	26627737	HeLa	viability after 8 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	0.28507874472155037	[508]	[295,169,343]	2	hSpCas9	negative selection	1455066
21015848	21015871	17	-	26627737	HeLa	viability after 12 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	0.05913762044536375	[876]	[593,217,343]	0	hSpCas9	negative selection	1537376
21017941	21017964	17	-	26627737	HeLa	viability after 12 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	0.0590118875179515	[92]	[24,36,57]	0	hSpCas9	negative selection	1537377
21019112	21019135	17	-	26627737	HeLa	viability after 12 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.4798787281970459	[461]	[233,217,350]	4	hSpCas9	negative selection	1537378
21021140	21021163	17	-	26627737	HeLa	viability after 12 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.36066518124330166	[706]	[396,81,223]	-3	hSpCas9	negative selection	1537379
21028630	21028653	17	-	26627737	HeLa	viability after 12 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	-0.24835522509904195	[761]	[241,308,238]	-2	hSpCas9	negative selection	1537380
21043609	21043632	17	-	26627737	HeLa	viability after 12 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	-0.8442682733022123	[508]	[94,77,181]	-6	hSpCas9	negative selection	1537381
21015848	21015871	17	-	26627737	HeLa	viability after 15 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.056619903674546945	[876]	[390,297,339]	0	hSpCas9	negative selection	1619691
21017941	21017964	17	-	26627737	HeLa	viability after 15 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.23434063606751243	[92]	[0,26,71]	-2	hSpCas9	negative selection	1619692
21019112	21019135	17	-	26627737	HeLa	viability after 15 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.6694145037071918	[461]	[288,363,239]	5	hSpCas9	negative selection	1619693
21021140	21021163	17	-	26627737	HeLa	viability after 15 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.681714543721269	[706]	[267,139,124]	-5	hSpCas9	negative selection	1619694
21028630	21028653	17	-	26627737	HeLa	viability after 15 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	-0.20042623994898057	[761]	[135,316,365]	-2	hSpCas9	negative selection	1619695
21043609	21043632	17	-	26627737	HeLa	viability after 15 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	0.20455863395322627	[508]	[279,230,201]	1	hSpCas9	negative selection	1619696
21015848	21015871	17	-	26627737	HeLa	viability after 18 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.06344094904593578	[876]	[258,246,339]	0	hSpCas9	negative selection	1702006
21017941	21017964	17	-	26627737	HeLa	viability after 18 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.17909729029973587	[92]	[0,24,71]	-1	hSpCas9	negative selection	1702007
21019112	21019135	17	-	26627737	HeLa	viability after 18 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.7200137529554562	[461]	[206,310,239]	5	hSpCas9	negative selection	1702008
21021140	21021163	17	-	26627737	HeLa	viability after 18 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.6642869726939962	[706]	[183,115,124]	-5	hSpCas9	negative selection	1702009
21028630	21028653	17	-	26627737	HeLa	viability after 18 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	-0.2065900974624092	[761]	[94,254,365]	-2	hSpCas9	negative selection	1702010
21043609	21043632	17	-	26627737	HeLa	viability after 18 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	0.21480323946062718	[508]	[192,188,201]	1	hSpCas9	negative selection	1702011
21015848	21015871	17	-	26627737	HCT116	viability after 6 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.35161683085248685	[1274]	[314,69]	-2	hSpCas9	negative selection	1784321
21017941	21017964	17	-	26627737	HCT116	viability after 6 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-4.25260680562609	[457]	[6,1]	-9	hSpCas9	negative selection	1784322
21019112	21019135	17	-	26627737	HCT116	viability after 6 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	-0.7765307376044174	[672]	[151,11]	-4	hSpCas9	negative selection	1784323
21021140	21021163	17	-	26627737	HCT116	viability after 6 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	0.8319588898149404	[1015]	[759,21]	4	hSpCas9	negative selection	1784324
21028630	21028653	17	-	26627737	HCT116	viability after 6 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	1.7173098088065095	[1124]	[616,561]	8	hSpCas9	negative selection	1784325
21043609	21043632	17	-	26627737	HCT116	viability after 6 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	1.3956839932825966	[563]	[231,233]	7	hSpCas9	negative selection	1784326
21015848	21015871	17	-	26627737	HCT116	viability after 8 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.2960742710022688	[751]	[335,301,373]	-3	hSpCas9	negative selection	1866636
21017941	21017964	17	-	26627737	HCT116	viability after 8 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.8227836035177176	[86]	[15,28,35]	-7	hSpCas9	negative selection	1866637
21019112	21019135	17	-	26627737	HCT116	viability after 8 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.34349420960857735	[454]	[280,297,373]	4	hSpCas9	negative selection	1866638
21021140	21021163	17	-	26627737	HCT116	viability after 8 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.3867020373071489	[601]	[262,216,280]	-4	hSpCas9	negative selection	1866639
21028630	21028653	17	-	26627737	HCT116	viability after 8 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	-0.38645045896230246	[510]	[233,233,178]	-4	hSpCas9	negative selection	1866640
21043609	21043632	17	-	26627737	HCT116	viability after 8 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	0.3754339496078002	[133]	[125,74,86]	4	hSpCas9	negative selection	1866641
21015848	21015871	17	-	26627737	HCT116	viability after 9 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	0.1314613114771861	[1274]	[158,541]	1	hSpCas9	negative selection	1948951
21017941	21017964	17	-	26627737	HCT116	viability after 9 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-1.0617401346533244	[457]	[52,62]	-6	hSpCas9	negative selection	1948952
21019112	21019135	17	-	26627737	HCT116	viability after 9 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.9295952365592671	[672]	[143,498]	6	hSpCas9	negative selection	1948953
21021140	21021163	17	-	26627737	HCT116	viability after 9 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-1.0869478532137848	[1015]	[139,117]	-6	hSpCas9	negative selection	1948954
21028630	21028653	17	-	26627737	HCT116	viability after 9 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	0.7381807831330124	[1124]	[361,610]	5	hSpCas9	negative selection	1948955
21043609	21043632	17	-	26627737	HCT116	viability after 9 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	0.7475070314538714	[563]	[406,130]	5	hSpCas9	negative selection	1948956
21015848	21015871	17	-	26627737	HCT116	viability after 12 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.515724221751591	[751]	[349,243,227]	-5	hSpCas9	negative selection	2031266
21017941	21017964	17	-	26627737	HCT116	viability after 12 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.11450625315134388	[86]	[58,32,32]	-1	hSpCas9	negative selection	2031267
21019112	21019135	17	-	26627737	HCT116	viability after 12 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.20614225974733813	[454]	[233,184,409]	2	hSpCas9	negative selection	2031268
21021140	21021163	17	-	26627737	HCT116	viability after 12 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.45646529112608103	[601]	[179,266,249]	-5	hSpCas9	negative selection	2031269
21028630	21028653	17	-	26627737	HCT116	viability after 12 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	-0.14085827662018702	[510]	[240,246,242]	-1	hSpCas9	negative selection	2031270
21043609	21043632	17	-	26627737	HCT116	viability after 12 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	0.8698934875444111	[133]	[118,89,176]	7	hSpCas9	negative selection	2031271
21015848	21015871	17	-	26627737	HCT116	viability after 15 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.3111204510497503	[751]	[356,309,377]	-3	hSpCas9	negative selection	2113581
21017941	21017964	17	-	26627737	HCT116	viability after 15 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-1.3123053151331738	[86]	[31,25,3]	-8	hSpCas9	negative selection	2113582
21019112	21019135	17	-	26627737	HCT116	viability after 15 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.0823644473466808	[454]	[300,177,352]	0	hSpCas9	negative selection	2113583
21021140	21021163	17	-	26627737	HCT116	viability after 15 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.37370861591110516	[601]	[388,129,295]	-4	hSpCas9	negative selection	2113584
21028630	21028653	17	-	26627737	HCT116	viability after 15 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	-0.5556074225554669	[510]	[129,217,241]	-5	hSpCas9	negative selection	2113585
21043609	21043632	17	-	26627737	HCT116	viability after 15 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	1.4268199934135328	[133]	[192,135,288]	9	hSpCas9	negative selection	2113586
21015848	21015871	17	-	26627737	HCT116	viability after 18 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.205449644365286	[751]	[454,239,252]	-2	hSpCas9	negative selection	2195896
21017941	21017964	17	-	26627737	HCT116	viability after 18 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.2372047687531469	[86]	[10,11,87]	-2	hSpCas9	negative selection	2195897
21019112	21019135	17	-	26627737	HCT116	viability after 18 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.4765628079753226	[454]	[192,302,427]	4	hSpCas9	negative selection	2195898
21021140	21021163	17	-	26627737	HCT116	viability after 18 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.7248945169080294	[601]	[200,210,110]	-6	hSpCas9	negative selection	2195899
21028630	21028653	17	-	26627737	HCT116	viability after 18 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	-0.24140527115906685	[510]	[177,126,332]	-2	hSpCas9	negative selection	2195900
21043609	21043632	17	-	26627737	HCT116	viability after 18 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	1.0472365291861636	[133]	[170,46,191]	7	hSpCas9	negative selection	2195901
21042739	21042762	17	+	24336569	HL60	viability	TGTCCACCTTGAAGCTGCCCAGG	USP22	ENSG00000124422	-0.8528018083163642	[983]	[1152]	-6	hSpCas9	negative selection	2305392
21042745	21042768	17	-	24336569	HL60	viability	CTCGCACCTGGGCAGCTTCAAGG	USP22	ENSG00000124422	1.081671735150777	[212]	[953]	8	hSpCas9	negative selection	2305393
21042753	21042776	17	+	24336569	HL60	viability	CTGCCCAGGTGCGAGCAGCCCGG	USP22	ENSG00000124422	1.0898787830316112	[451]	[2035]	8	hSpCas9	negative selection	2305394
21042771	21042794	17	-	24336569	HL60	viability	GAGCTGGCGGTAGCGCCGCCGGG	USP22	ENSG00000124422	0.7020313572397543	[539]	[1858]	6	hSpCas9	negative selection	2305395
21042782	21042805	17	+	24336569	HL60	viability	TACCGCCAGCTCGGCGTCCATGG	USP22	ENSG00000124422	0.8057785934707362	[275]	[1020]	6	hSpCas9	negative selection	2305396
21042787	21042810	17	-	24336569	HL60	viability	CGAGGCCATGGACGCCGAGCTGG	USP22	ENSG00000124422	0.5948093063814435	[300]	[961]	5	hSpCas9	negative selection	2305397
21042794	21042817	17	+	24336569	HL60	viability	GGCGTCCATGGCCTCGCCCTCGG	USP22	ENSG00000124422	0.45822432032781923	[204]	[595]	4	hSpCas9	negative selection	2305398
21042799	21042822	17	-	24336569	HL60	viability	AGAGCCCGAGGGCGAGGCCATGG	USP22	ENSG00000124422	-0.2168311924820847	[775]	[1412]	-2	hSpCas9	negative selection	2305399
21042810	21042833	17	-	24336569	HL60	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	-0.4409436234174281	[432]	[674]	-4	hSpCas9	negative selection	2305400
21042815	21042838	17	+	24336569	HL60	viability	GGGCTCTGGCCGGGACACCATGG	USP22	ENSG00000124422	2.1139429302270965	[105]	[970]	9	hSpCas9	negative selection	2305401
21042739	21042762	17	+	24336569	KBM7	viability	TGTCCACCTTGAAGCTGCCCAGG	USP22	ENSG00000124422	-0.1951920349145972	[407]	[971]	-2	hSpCas9	negative selection	2372569
21042745	21042768	17	-	24336569	KBM7	viability	CTCGCACCTGGGCAGCTTCAAGG	USP22	ENSG00000124422	0.7733970127950845	[363]	[1696]	7	hSpCas9	negative selection	2372570
21042753	21042776	17	+	24336569	KBM7	viability	CTGCCCAGGTGCGAGCAGCCCGG	USP22	ENSG00000124422	1.1240180460862286	[487]	[2900]	8	hSpCas9	negative selection	2372571
21042771	21042794	17	-	24336569	KBM7	viability	GAGCTGGCGGTAGCGCCGCCGGG	USP22	ENSG00000124422	0.7128854756443634	[373]	[1671]	6	hSpCas9	negative selection	2372572
21042782	21042805	17	+	24336569	KBM7	viability	TACCGCCAGCTCGGCGTCCATGG	USP22	ENSG00000124422	1.1603932822187741	[310]	[1895]	8	hSpCas9	negative selection	2372573
21042787	21042810	17	-	24336569	KBM7	viability	CGAGGCCATGGACGCCGAGCTGG	USP22	ENSG00000124422	1.2521253903452774	[301]	[1961]	8	hSpCas9	negative selection	2372574
21042794	21042817	17	+	24336569	KBM7	viability	GGCGTCCATGGCCTCGCCCTCGG	USP22	ENSG00000124422	-1.4770229744413645	[296]	[290]	-7	hSpCas9	negative selection	2372575
21042799	21042822	17	-	24336569	KBM7	viability	AGAGCCCGAGGGCGAGGCCATGG	USP22	ENSG00000124422	-0.5295110516288785	[479]	[906]	-4	hSpCas9	negative selection	2372576
21042810	21042833	17	-	24336569	KBM7	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	0.4711500670950367	[355]	[1345]	4	hSpCas9	negative selection	2372577
21042815	21042838	17	+	24336569	KBM7	viability	GGGCTCTGGCCGGGACACCATGG	USP22	ENSG00000124422	-0.2657408735630693	[200]	[455]	-2	hSpCas9	negative selection	2372578
21023373	21023396	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGTGAGCCACCACGCCGGG	USP22	ENSG00000124422	1.2080578617800355	[188,10]	[73,23]	5	dCas9-VP64	positive selection	2430232
21026712	21026735	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAGGCCACAG	USP22	ENSG00000124422	-3.2327828351083694	[281,50]	[1,4]	-9	dCas9-VP64	positive selection	2431311
21043186	21043209	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTAACGGGCGCGCGAGTGTGGGG	USP22	ENSG00000124422	0.49851755092967687	[18,316]	[31,74]	2	dCas9-VP64	positive selection	2445505
21043211	21043234	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTGGGTAGACCCGCGCCCGAGG	USP22	ENSG00000124422	2.5913410214240686	[7,29]	[35,14]	8	dCas9-VP64	positive selection	2445506
21043138	21043161	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCAGTGCGGTGCCGGCCGGG	USP22	ENSG00000124422	0.517773607176431	[70,7]	[18,4]	2	dCas9-VP64	positive selection	2445507
21023373	21023396	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGTGAGCCACCACGCCGGG	USP22	ENSG00000124422	1.0270683763310697	[166,152]	[69,140]	6	dCas9-VP64	positive selection	2525487
21026712	21026735	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAGGCCACAG	USP22	ENSG00000124422	0.5850522226976638	[88,64]	[38,35]	4	dCas9-VP64	positive selection	2526566
21043186	21043209	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTAACGGGCGCGCGAGTGTGGGG	USP22	ENSG00000124422	-1.267936518132034	[224,51]	[21,14]	-9	dCas9-VP64	positive selection	2540760
21043211	21043234	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTGGGTAGACCCGCGCCCGAGG	USP22	ENSG00000124422	-0.5274901455904626	[27,25]	[4,6]	-5	dCas9-VP64	positive selection	2540761
21043138	21043161	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCAGTGCGGTGCCGGCCGGG	USP22	ENSG00000124422	-0.04861715043911796	[98,29]	[9,29]	0	dCas9-VP64	positive selection	2540762
21042757	21042780	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCCAGGTGCGAGCAGCCCGGCGG	USP22	ENSG00000124422	0.7753421558637568	[3,2]	[5,4]	9	hSpCas9	positive selection	3031310
21021158	21021181	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACATCTATGACAAAGACATGG	USP22	ENSG00000124422	0.6707265856947623	[2,3]	[3,5]	9	hSpCas9	positive selection	3031311
21017941	21017964	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	1.0393837061599402	[4,4]	[5,11]	9	hSpCas9	positive selection	3031312
21021205	21021228	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	-0.03230836151562691	[3,3]	[3,2]	0	hSpCas9	positive selection	3031313
21042757	21042780	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCCAGGTGCGAGCAGCCCGGCGG	USP22	ENSG00000124422	0.07484365161988352	[3,3]	[3,1]	1	hSpCas9	positive selection	3099168
21021158	21021181	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACATCTATGACAAAGACATGG	USP22	ENSG00000124422	0.4431661404288526	[2,2]	[3,2]	7	hSpCas9	positive selection	3099169
21017941	21017964	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	0.046006130674914825	[4,4]	[4,2]	0	hSpCas9	positive selection	3099170
21021205	21021228	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.2587216136862459	[3,3]	[3,2]	4	hSpCas9	positive selection	3099171
21021123	21021146		-	24336571	A375	resistance to PLX after 7 days	AGGAGGAGCAGCGAAAAGCTTGG	USP22	ENSG00000124422	0.1962307534675172	[9,10]	[12,10]	6	hSpCas9	positive selection	3154579
21018025	21018048		+	24336571	A375	resistance to PLX after 7 days	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.36236220676256614	[9,10]	[12,12]	8	hSpCas9	positive selection	3154580
21018055	21018078		-	24336571	A375	resistance to PLX after 7 days	CTTCATGAACTGCATCGTGCAGG	USP22	ENSG00000124422	0.16393876186120868	[10,10]	[11,11]	5	hSpCas9	positive selection	3154581
21021204	21021227		+	24336571	A375	resistance to PLX after 7 days	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.10702080816408399	[8,7]	[10,7]	3	hSpCas9	positive selection	3154582
21021123	21021146		-	24336571	A375	resistance to PLX after 14 days	AGGAGGAGCAGCGAAAAGCTTGG	USP22	ENSG00000124422	0.6218124508152865	[8,13]	[9,6]	5	hSpCas9	positive selection	3212372
21018025	21018048		+	24336571	A375	resistance to PLX after 14 days	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.9696473943236673	[10,7]	[6,9]	7	hSpCas9	positive selection	3212373
21018055	21018078		-	24336571	A375	resistance to PLX after 14 days	CTTCATGAACTGCATCGTGCAGG	USP22	ENSG00000124422	0.0033313510262369117	[14,13]	[5,6]	0	hSpCas9	positive selection	3212374
21021204	21021227		+	24336571	A375	resistance to PLX after 14 days	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.6046547623012417	[5,5]	[3,3]	5	hSpCas9	positive selection	3212375
21021123	21021146		-	24336571	A375	viability after 7 days	AGGAGGAGCAGCGAAAAGCTTGG	USP22	ENSG00000124422	-0.007574509708841298	[10]	[9,10]	0	hSpCas9	negative selection	3270165
21018025	21018048		+	24336571	A375	viability after 7 days	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.7942164164719943	[5]	[9,10]	9	hSpCas9	negative selection	3270166
21018055	21018078		-	24336571	A375	viability after 7 days	CTTCATGAACTGCATCGTGCAGG	USP22	ENSG00000124422	-0.05300054776437885	[11]	[10,10]	0	hSpCas9	negative selection	3270167
21021204	21021227		+	24336571	A375	viability after 7 days	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.6015854140614671	[13]	[8,7]	-7	hSpCas9	negative selection	3270168
21021123	21021146		-	24336571	A375	viability after 14 days	AGGAGGAGCAGCGAAAAGCTTGG	USP22	ENSG00000124422	0.10576706896550236	[10]	[8,13]	1	hSpCas9	negative selection	3327958
21018025	21018048		+	24336571	A375	viability after 14 days	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.6724455466482543	[5]	[10,7]	8	hSpCas9	negative selection	3327959
21018055	21018078		-	24336571	A375	viability after 14 days	CTTCATGAACTGCATCGTGCAGG	USP22	ENSG00000124422	0.3451359762048941	[11]	[14,13]	4	hSpCas9	negative selection	3327960
21021204	21021227		+	24336571	A375	viability after 14 days	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-1.093122918963758	[13]	[5,5]	-8	hSpCas9	negative selection	3327961
21018087	21018110	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	-0.9472449328033686	[294,294]	[0,0]	-6	hSpCas9	positive selection	3400568
21021164	21021187	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-1.3610592908127714	[392,392]	[0,0]	-8	hSpCas9	positive selection	3400569
21012819	21012842	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.6435405965349134	[238,238]	[0,0]	-4	hSpCas9	positive selection	3400570
21042756	21042779	17	+	26780180	HT29	viability (Avana library 4 designs)	CCCAGGTGCGAGCAGCCCGGCGG	USP22	ENSG00000124422	0.501308508351213	[]	[]	1	hSpCas9	negative selection	3470504
21021158	21021181	17	-	26780180	HT29	viability (Avana library 4 designs)	CTACATCTATGACAAAGACATGG	USP22	ENSG00000124422	-0.205589090217516	[]	[]	-3	hSpCas9	negative selection	3470505
21017941	21017964	17	-	26780180	HT29	viability (Avana library 4 designs)	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	0.42161115801597	[]	[]	1	hSpCas9	negative selection	3470506
21021205	21021228	17	-	26780180	HT29	viability (Avana library 4 designs)	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.25380393406515	[]	[]	0	hSpCas9	negative selection	3470507
21042756	21042779	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCCAGGTGCGAGCAGCCCGGCGG	USP22	ENSG00000124422	3.67457337297698	[]	[]	6	hSpCas9	negative selection	3576673
21021205	21021228	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	-6.0589505793743	[]	[]	-6	hSpCas9	negative selection	3576674
21017941	21017964	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-3.46815570460064	[]	[]	-4	hSpCas9	negative selection	3576675
21021158	21021181	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACATCTATGACAAAGACATGG	USP22	ENSG00000124422	-11.9611745420105	[]	[]	-8	hSpCas9	negative selection	3576676
21017983	21018006	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGGGGCTCTGCATCTCACAGCGG	USP22	ENSG00000124422	2.19369055323918	[]	[]	3	hSpCas9	negative selection	3576677
21017936	21017959	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCACCTCCTGAAACAGTGAGG	USP22	ENSG00000124422	-2.50211799666059	[]	[]	-3	hSpCas9	negative selection	3576678
21042756	21042779	17	+	26780180	A375	viability (Avana lentiGuide)	CCCAGGTGCGAGCAGCCCGGCGG	USP22	ENSG00000124422	2.54374219379884	[]	[]	2	hSpCas9	negative selection	3685332
21021205	21021228	17	-	26780180	A375	viability (Avana lentiGuide)	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	17.9917861190778	[]	[]	8	hSpCas9	negative selection	3685333
21017941	21017964	17	-	26780180	A375	viability (Avana lentiGuide)	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	12.6611999517301	[]	[]	7	hSpCas9	negative selection	3685334
21021158	21021181	17	-	26780180	A375	viability (Avana lentiGuide)	CTACATCTATGACAAAGACATGG	USP22	ENSG00000124422	5.50640971675926	[]	[]	5	hSpCas9	negative selection	3685335
21017983	21018006	17	+	26780180	A375	viability (Avana lentiGuide)	TGGGGCTCTGCATCTCACAGCGG	USP22	ENSG00000124422	6.18500709493562	[]	[]	5	hSpCas9	negative selection	3685336
21017936	21017959	17	+	26780180	A375	viability (Avana lentiGuide)	GCTCACCTCCTGAAACAGTGAGG	USP22	ENSG00000124422	8.51268712999332	[]	[]	6	hSpCas9	negative selection	3685337
21042756	21042779	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCCAGGTGCGAGCAGCCCGGCGG	USP22	ENSG00000124422	0.3094660869705258	[3]	[5,4]	8	hSpCas9	positive selection	3793939
21021205	21021228	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	-0.3972179465205144	[4]	[4,2]	-5	hSpCas9	positive selection	3793940
21017941	21017964	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.5516810441041463	[5]	[3,2]	-7	hSpCas9	positive selection	3793941
21021158	21021181	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACATCTATGACAAAGACATGG	USP22	ENSG00000124422	-1.1036991893532526	[5]	[2,1]	-9	hSpCas9	positive selection	3793942
21017983	21018006	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGGGCTCTGCATCTCACAGCGG	USP22	ENSG00000124422	0.19260374989313223	[5]	[6,6]	5	hSpCas9	positive selection	3793943
21017936	21017959	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCACCTCCTGAAACAGTGAGG	USP22	ENSG00000124422	-0.36143655878706094	[4]	[3,2]	-5	hSpCas9	positive selection	3793944
21042756	21042779	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCCAGGTGCGAGCAGCCCGGCGG	USP22	ENSG00000124422	-0.05991640673080145	[4]	[4,2]	-1	hSpCas9	positive selection	3902546
21021205	21021228	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	-0.5997498602528276	[5]	[3,1]	-6	hSpCas9	positive selection	3902547
21017941	21017964	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.3756112549775088	[6]	[4,3]	-5	hSpCas9	positive selection	3902548
21021158	21021181	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACATCTATGACAAAGACATGG	USP22	ENSG00000124422	-0.35906995660834135	[5]	[4,2]	-5	hSpCas9	positive selection	3902549
21017983	21018006	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGGGCTCTGCATCTCACAGCGG	USP22	ENSG00000124422	0.04023361748134846	[6]	[5,5]	0	hSpCas9	positive selection	3902550
21017936	21017959	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCACCTCCTGAAACAGTGAGG	USP22	ENSG00000124422	0.06229598129628709	[5]	[5,4]	1	hSpCas9	positive selection	3902551
21018025	21018048	17	+	26780180	A375	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	1.32043882619135	[]	[]	7	hSpCas9	negative selection	4010878
21012819	21012842	17	+	26780180	A375	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	1.54692665257516	[]	[]	8	hSpCas9	negative selection	4010879
21018087	21018110	17	-	26780180	A375	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	1.37434895226827	[]	[]	7	hSpCas9	negative selection	4010880
21021164	21021187	17	+	26780180	A375	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	1.75916268314249	[]	[]	9	hSpCas9	negative selection	4010881
21012858	21012881	17	+	26780180	A375	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.949732592836275	[]	[]	4	hSpCas9	negative selection	4010882
21021204	21021227	17	+	26780180	A375	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	1.66139553180044	[]	[]	8	hSpCas9	negative selection	4010883
21018025	21018048	17	+	26780180	HT29	viability (GeCKOv2 library)	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.00342104403721207	[]	[]	0	hSpCas9	negative selection	4118844
21012819	21012842	17	+	26780180	HT29	viability (GeCKOv2 library)	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.0761827269419731	[]	[]	-2	hSpCas9	negative selection	4118845
21018087	21018110	17	-	26780180	HT29	viability (GeCKOv2 library)	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.683380030302571	[]	[]	2	hSpCas9	negative selection	4118846
21021164	21021187	17	+	26780180	HT29	viability (GeCKOv2 library)	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	0.59619845882722	[]	[]	2	hSpCas9	negative selection	4118847
21012858	21012881	17	+	26780180	HT29	viability (GeCKOv2 library)	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.877557795113252	[]	[]	4	hSpCas9	negative selection	4118848
21021204	21021227	17	+	26780180	HT29	viability (GeCKOv2 library)	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.263084032152035	[]	[]	0	hSpCas9	negative selection	4118849
21021123	21021146	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGAGGAGCAGCGAAAAGCTTGG	USP22	ENSG00000124422	-0.03252641288174866	[3]	[1,2]	-1	hSpCas9	positive selection	4181298
21018025	21018048	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.2521805522056149	[2]	[1,2]	6	hSpCas9	positive selection	4181299
21018055	21018078	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCATGAACTGCATCGTGCAGG	USP22	ENSG00000124422	0.09181138859477174	[3]	[1,2]	2	hSpCas9	positive selection	4181300
21021204	21021227	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.26943460111755	[3]	[1,1]	-6	hSpCas9	positive selection	4181301
21021123	21021146	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGAGGAGCAGCGAAAAGCTTGG	USP22	ENSG00000124422	0.6056850093410104	[3]	[3,3,3,0]	4	hSpCas9	positive selection	4245320
21018025	21018048	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.1752485970608181	[4]	[3,3,2,0]	1	hSpCas9	positive selection	4245321
21018055	21018078	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCATGAACTGCATCGTGCAGG	USP22	ENSG00000124422	-0.40264663094714603	[3]	[1,1,0,0]	-6	hSpCas9	positive selection	4245322
21021204	21021227	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.25477527397605126	[4]	[2,1,1,0]	-4	hSpCas9	positive selection	4245323
21018025	21018048	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.31118821122904783	[2]	[3,2]	6	hSpCas9	positive selection	4306923
21012858	21012881	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.17023265408958996	[3]	[2,2]	3	hSpCas9	positive selection	4306924
21021204	21021227	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.2383265833171575	[3]	[3,3]	5	hSpCas9	positive selection	4306925
21018087	21018110	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.23207871950664755	[3]	[3,3]	4	hSpCas9	positive selection	4371170
21021164	21021187	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	0.16551528902468166	[4]	[4,3]	3	hSpCas9	positive selection	4371171
21012819	21012842	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.3403661121259238	[3]	[3,1]	-6	hSpCas9	positive selection	4371172
21021205	21021227	17	-	27760321	OCIAML3	viability	CCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.04672839698125353	[741,558]	[452,609]	0	hSpCas9	negative selection	4452673
21028541	21028563	17	-	27760321	OCIAML3	viability	AGGCGAAGCGGCACAACCTGGG	USP22	ENSG00000124422	-1.0145238770174012	[436,306]	[131,155]	-7	hSpCas9	negative selection	4452674
21028560	21028582	17	-	27760321	OCIAML3	viability	CATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-1.2228542695051319	[327,285]	[86,122]	-8	hSpCas9	negative selection	4452675
21015820	21015842	17	-	27760321	OCIAML3	viability	CCCACGCGAGGCACCTAGCAGG	USP22	ENSG00000124422	0.11247969991579365	[871,754]	[639,745]	1	hSpCas9	negative selection	4452676
21018026	21018048	17	+	27760321	OCIAML3	viability	GTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-0.9808772381018569	[1176,1031]	[332,571]	-7	hSpCas9	negative selection	4452677
21021205	21021227	17	-	27760321	OCIAML2	viability	CCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.04272374196313766	[741,558]	[433,673]	0	hSpCas9	negative selection	4536136
21028541	21028563	17	-	27760321	OCIAML2	viability	AGGCGAAGCGGCACAACCTGGG	USP22	ENSG00000124422	-0.6986520869863774	[436,306]	[191,171]	-6	hSpCas9	negative selection	4536137
21028560	21028582	17	-	27760321	OCIAML2	viability	CATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-0.24256699242037383	[327,285]	[167,263]	-3	hSpCas9	negative selection	4536138
21015820	21015842	17	-	27760321	OCIAML2	viability	CCCACGCGAGGCACCTAGCAGG	USP22	ENSG00000124422	0.42535772521008786	[871,754]	[754,1047]	6	hSpCas9	negative selection	4536139
21018026	21018048	17	+	27760321	OCIAML2	viability	GTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.16791061323415635	[1176,1031]	[882,1157]	2	hSpCas9	negative selection	4536140
21021205	21021227	17	-	27760321	MV411	viability	CCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.5130643100791653	[741,558]	[527,726]	3	hSpCas9	negative selection	4619599
21028541	21028563	17	-	27760321	MV411	viability	AGGCGAAGCGGCACAACCTGGG	USP22	ENSG00000124422	-0.9109114776153411	[436,306]	[27,280]	-6	hSpCas9	negative selection	4619600
21028560	21028582	17	-	27760321	MV411	viability	CATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-1.1424738317227103	[327,285]	[37,171]	-6	hSpCas9	negative selection	4619601
21015820	21015842	17	-	27760321	MV411	viability	CCCACGCGAGGCACCTAGCAGG	USP22	ENSG00000124422	0.8323580249044366	[871,754]	[1159,642]	6	hSpCas9	negative selection	4619602
21018026	21018048	17	+	27760321	MV411	viability	GTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-0.921946364118539	[1176,1031]	[239,599]	-6	hSpCas9	negative selection	4619603
21021205	21021227	17	-	27760321	HL60	viability	CCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.3915872103903659	[741,558]	[585,802]	5	hSpCas9	negative selection	4703062
21028541	21028563	17	-	27760321	HL60	viability	AGGCGAAGCGGCACAACCTGGG	USP22	ENSG00000124422	1.8460622432533973	[436,306]	[944,1223]	9	hSpCas9	negative selection	4703063
21028560	21028582	17	-	27760321	HL60	viability	CATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	1.2491058514206652	[327,285]	[501,692]	9	hSpCas9	negative selection	4703064
21015820	21015842	17	-	27760321	HL60	viability	CCCACGCGAGGCACCTAGCAGG	USP22	ENSG00000124422	0.1684062105727756	[871,754]	[739,749]	2	hSpCas9	negative selection	4703065
21018026	21018048	17	+	27760321	HL60	viability	GTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	1.548166033542072	[1176,1031]	[2566,2702]	9	hSpCas9	negative selection	4703066
21021205	21021227	17	-	27760321	HT1080	viability	CCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	1.3024569247968247	[558,435]	[526,446]	7	hSpCas9	negative selection	4786525
21028541	21028563	17	-	27760321	HT1080	viability	AGGCGAAGCGGCACAACCTGGG	USP22	ENSG00000124422	2.209092986886706	[306,239]	[373,645]	9	hSpCas9	negative selection	4786526
21028560	21028582	17	-	27760321	HT1080	viability	CATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	4.330686903102803	[285,222]	[2301,1752]	9	hSpCas9	negative selection	4786527
21015820	21015842	17	-	27760321	HT1080	viability	CCCACGCGAGGCACCTAGCAGG	USP22	ENSG00000124422	0.9510254229767598	[754,588]	[359,689]	5	hSpCas9	negative selection	4786528
21018026	21018048	17	+	27760321	HT1080	viability	GTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-0.7549240962512439	[1031,804]	[212,220]	-3	hSpCas9	negative selection	4786529
21021205	21021227	17	-	27760321	HT29	viability after 7 days	CCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.10582300996740057	[558,435]	[853,496,734]	1	hSpCas9	negative selection	4869988
21028541	21028563	17	-	27760321	HT29	viability after 7 days	AGGCGAAGCGGCACAACCTGGG	USP22	ENSG00000124422	0.32654023593162773	[306,239]	[581,335,424]	5	hSpCas9	negative selection	4869989
21028560	21028582	17	-	27760321	HT29	viability after 7 days	CATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	0.36964528139160846	[285,222]	[362,310,579]	5	hSpCas9	negative selection	4869990
21015820	21015842	17	-	27760321	HT29	viability after 7 days	CCCACGCGAGGCACCTAGCAGG	USP22	ENSG00000124422	0.6765661290173846	[754,588]	[925,1390,1746]	8	hSpCas9	negative selection	4869991
21018026	21018048	17	+	27760321	HT29	viability after 7 days	GTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.5096822742898983	[1031,804]	[1843,1806,1421]	7	hSpCas9	negative selection	4869992
21021205	21021227	17	-	27760321	HT29	viability after 25 days	CCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.54175096222776	[558,435]	[1013,773,664]	6	hSpCas9	negative selection	4953451
21028541	21028563	17	-	27760321	HT29	viability after 25 days	AGGCGAAGCGGCACAACCTGGG	USP22	ENSG00000124422	1.0427119356395207	[306,239]	[399,861,688]	9	hSpCas9	negative selection	4953452
21028560	21028582	17	-	27760321	HT29	viability after 25 days	CATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	0.7113550231422615	[285,222]	[509,574,324]	7	hSpCas9	negative selection	4953453
21015820	21015842	17	-	27760321	HT29	viability after 25 days	CCCACGCGAGGCACCTAGCAGG	USP22	ENSG00000124422	0.9103241017850479	[754,588]	[1380,1048,1954]	9	hSpCas9	negative selection	4953454
21018026	21018048	17	+	27760321	HT29	viability after 25 days	GTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	1.2159900255953349	[1031,804]	[2346,2066,2956]	9	hSpCas9	negative selection	4953455
21021205	21021227	17	-	27760321	HT29	viability after 22 days	CCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.6819698322325914	[558,435]	[646,1144,983]	7	hSpCas9	negative selection	5036914
21028541	21028563	17	-	27760321	HT29	viability after 22 days	AGGCGAAGCGGCACAACCTGGG	USP22	ENSG00000124422	0.6856377605079449	[306,239]	[553,414,555]	7	hSpCas9	negative selection	5036915
21028560	21028582	17	-	27760321	HT29	viability after 22 days	CATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	0.5495386995527164	[285,222]	[367,541,382]	6	hSpCas9	negative selection	5036916
21015820	21015842	17	-	27760321	HT29	viability after 22 days	CCCACGCGAGGCACCTAGCAGG	USP22	ENSG00000124422	0.961584138758661	[754,588]	[1207,1383,1958]	9	hSpCas9	negative selection	5036917
21018026	21018048	17	+	27760321	HT29	viability after 22 days	GTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	1.2030499189610562	[1031,804]	[2300,2629,2405]	9	hSpCas9	negative selection	5036918
21021205	21021227	17	-	27760321	HT29	viability after 19 days	CCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.7803173745669222	[558,435]	[1087,863,989]	7	hSpCas9	negative selection	5120377
21028541	21028563	17	-	27760321	HT29	viability after 19 days	AGGCGAAGCGGCACAACCTGGG	USP22	ENSG00000124422	1.1023182617262925	[306,239]	[720,636,661]	9	hSpCas9	negative selection	5120378
21028560	21028582	17	-	27760321	HT29	viability after 19 days	CATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	1.1057211280735189	[285,222]	[382,1160,320]	9	hSpCas9	negative selection	5120379
21015820	21015842	17	-	27760321	HT29	viability after 19 days	CCCACGCGAGGCACCTAGCAGG	USP22	ENSG00000124422	1.0564679613738521	[754,588]	[1268,1364,2105]	9	hSpCas9	negative selection	5120380
21018026	21018048	17	+	27760321	HT29	viability after 19 days	GTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	1.290746906193283	[1031,804]	[2741,1983,2983]	9	hSpCas9	negative selection	5120381
21021205	21021227	17	-	27760321	HT29	viability after 16 days	CCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.7779094286395004	[558,435]	[959,969,932]	8	hSpCas9	negative selection	5203840
21028541	21028563	17	-	27760321	HT29	viability after 16 days	AGGCGAAGCGGCACAACCTGGG	USP22	ENSG00000124422	0.5055656909986914	[306,239]	[448,421,433]	6	hSpCas9	negative selection	5203841
21028560	21028582	17	-	27760321	HT29	viability after 16 days	CATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	0.22916257421852232	[285,222]	[341,445,210]	2	hSpCas9	negative selection	5203842
21015820	21015842	17	-	27760321	HT29	viability after 16 days	CCCACGCGAGGCACCTAGCAGG	USP22	ENSG00000124422	0.9266560723488717	[754,588]	[1557,940,1812]	9	hSpCas9	negative selection	5203843
21018026	21018048	17	+	27760321	HT29	viability after 16 days	GTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.9500572749242102	[1031,804]	[2009,2090,1853]	9	hSpCas9	negative selection	5203844
21021205	21021227	17	-	27760321	HT29	viability after 13 days	CCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.588879745064716	[558,435]	[757,922,919]	7	hSpCas9	negative selection	5287303
21028541	21028563	17	-	27760321	HT29	viability after 13 days	AGGCGAAGCGGCACAACCTGGG	USP22	ENSG00000124422	1.1088769677593702	[306,239]	[787,668,600]	9	hSpCas9	negative selection	5287304
21028560	21028582	17	-	27760321	HT29	viability after 13 days	CATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	0.4076507680734295	[285,222]	[476,482,224]	5	hSpCas9	negative selection	5287305
21015820	21015842	17	-	27760321	HT29	viability after 13 days	CCCACGCGAGGCACCTAGCAGG	USP22	ENSG00000124422	0.49514793573156735	[754,588]	[1294,1060,948]	6	hSpCas9	negative selection	5287306
21018026	21018048	17	+	27760321	HT29	viability after 13 days	GTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.8352295885998253	[1031,804]	[2163,1753,1790]	9	hSpCas9	negative selection	5287307
21021205	21021227	17	-	27760321	HT29	viability after 10 days	CCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.18533192570853518	[558,435]	[864,600,650]	2	hSpCas9	negative selection	5370766
21028541	21028563	17	-	27760321	HT29	viability after 10 days	AGGCGAAGCGGCACAACCTGGG	USP22	ENSG00000124422	0.18108351811037177	[306,239]	[326,343,486]	2	hSpCas9	negative selection	5370767
21028560	21028582	17	-	27760321	HT29	viability after 10 days	CATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	0.287818576004645	[285,222]	[549,282,328]	4	hSpCas9	negative selection	5370768
21015820	21015842	17	-	27760321	HT29	viability after 10 days	CCCACGCGAGGCACCTAGCAGG	USP22	ENSG00000124422	0.7958418023417628	[754,588]	[1532,1090,1728]	9	hSpCas9	negative selection	5370769
21018026	21018048	17	+	27760321	HT29	viability after 10 days	GTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.6328716861015504	[1031,804]	[1701,1824,1807]	8	hSpCas9	negative selection	5370770
21021205	21021227	17	-	27760321	MOLM13	viability	CCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	-0.2214996849382056	[741,558]	[403,233]	-1	hSpCas9	negative selection	5454229
21028541	21028563	17	-	27760321	MOLM13	viability	AGGCGAAGCGGCACAACCTGGG	USP22	ENSG00000124422	-1.3489358477431053	[436,306]	[0,149]	-6	hSpCas9	negative selection	5454230
21028560	21028582	17	-	27760321	MOLM13	viability	CATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-0.06638943865851166	[327,285]	[325,27]	0	hSpCas9	negative selection	5454231
21015820	21015842	17	-	27760321	MOLM13	viability	CCCACGCGAGGCACCTAGCAGG	USP22	ENSG00000124422	-0.059024144116758936	[871,754]	[574,323]	0	hSpCas9	negative selection	5454232
21018026	21018048	17	+	27760321	MOLM13	viability	GTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-0.37416475478142885	[1176,1031]	[401,545]	-2	hSpCas9	negative selection	5454233
21042467	21042490	17	+	27661255	K562	viability	GGAAGGGAGAGAGTTGAGGGGGG	USP22	ENSG00000124422	0.20325002126905295	[541,774]	[618,586]	7	dCas9-KRAB	negative selection	5521797
21042960	21042983	17	+	27661255	K562	viability	GCGGAGGCCGGACAAAGATGGGG	USP22	ENSG00000124422	0.15930171453907427	[231,336]	[243,258]	5	dCas9-KRAB	negative selection	5521798
21042982	21043005	17	+	27661255	K562	viability	GCTGCGCGATCGCCGAGGGGAGG	USP22	ENSG00000124422	0.1952532301424735	[928,786]	[860,723]	6	dCas9-KRAB	negative selection	5521799
21043067	21043090	17	+	27661255	K562	viability	GGTTCGCGGAGGGTGTCGCGGGG	USP22	ENSG00000124422	0.2839739991163698	[320,506]	[427,374]	8	dCas9-KRAB	negative selection	5521800
21042810	21042833	17	-	27661255	K562	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	0.033263207924958405	[1550,1854]	[1534,1261]	1	dCas9-KRAB	negative selection	5521801
21018025	21018048	17	+	27260156	BXPC3	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.17914457430731587	[349]	[339,386,352,606]	4	hSpCas9	negative selection	5579383
21012858	21012881	17	+	27260156	BXPC3	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.0979179500565614	[512]	[552,518,488,757]	2	hSpCas9	negative selection	5579384
21021204	21021227	17	+	27260156	BXPC3	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.0029038278813755536	[753]	[731,652,893,905]	0	hSpCas9	negative selection	5579385
21018087	21018110	17	-	27260156	BXPC3	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	-0.046894957682126814	[830]	[758,718,890,1029]	-1	hSpCas9	negative selection	5643630
21021164	21021187	17	+	27260156	BXPC3	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.27713471852235627	[1545]	[1382,1263,1287,1396]	-6	hSpCas9	negative selection	5643631
21012819	21012842	17	+	27260156	BXPC3	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.1077566493423916	[934]	[706,832,970,1171]	-3	hSpCas9	negative selection	5643632
21018025	21018048	17	+	27260156	A673	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.18246798843253909	[349]	[493,499,472,438]	4	hSpCas9	negative selection	5700634
21012858	21012881	17	+	27260156	A673	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.2671557341616763	[512]	[929,652,655,749]	6	hSpCas9	negative selection	5700635
21021204	21021227	17	+	27260156	A673	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.1360285851533236	[753]	[1042,988,978,970]	3	hSpCas9	negative selection	5700636
21018087	21018110	17	-	27260156	A673	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.1702268894406721	[830]	[1294,1018,1101,1093]	4	hSpCas9	negative selection	5764881
21021164	21021187	17	+	27260156	A673	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.11091507536862988	[1545]	[1948,1618,1797,1523]	-3	hSpCas9	negative selection	5764882
21012819	21012842	17	+	27260156	A673	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.3077463211420417	[934]	[1529,1032,1554,1465]	7	hSpCas9	negative selection	5764883
21018025	21018048	17	+	27260156	A375	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-0.9301322282617155	[349]	[172,273,274,150]	-8	hSpCas9	negative selection	5821885
21012858	21012881	17	+	27260156	A375	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.12580583098603454	[512]	[662,975,480,549]	1	hSpCas9	negative selection	5821886
21021204	21021227	17	+	27260156	A375	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-1.351184854932801	[753]	[395,321,381,283]	-9	hSpCas9	negative selection	5821887
21018087	21018110	17	-	27260156	A375	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	-0.4449391513134957	[830]	[957,781,650,495]	-6	hSpCas9	negative selection	5886132
21021164	21021187	17	+	27260156	A375	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.5358775665165523	[1545]	[1091,1389,1397,1129]	-6	hSpCas9	negative selection	5886133
21012819	21012842	17	+	27260156	A375	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.8367094077805033	[934]	[655,477,584,695]	-8	hSpCas9	negative selection	5886134
21018025	21018048	17	+	27260156	COLO741	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.14222286240773774	[349]	[492,458,524]	3	hSpCas9	negative selection	5943136
21012858	21012881	17	+	27260156	COLO741	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.48623879141833115	[512]	[990,828,936]	8	hSpCas9	negative selection	5943137
21021204	21021227	17	+	27260156	COLO741	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.18899098121365843	[753]	[1415,1033,884]	4	hSpCas9	negative selection	5943138
21018087	21018110	17	-	27260156	COLO741	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.32135154077325756	[830]	[1245,1196,1512]	6	hSpCas9	negative selection	6007383
21021164	21021187	17	+	27260156	COLO741	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.2112182898992776	[1545]	[1861,1782,1498]	-4	hSpCas9	negative selection	6007384
21012819	21012842	17	+	27260156	COLO741	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.045845682732565285	[934]	[1301,1353,1059]	1	hSpCas9	negative selection	6007385
21018025	21018048	17	+	27260156	CAL120	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.03572276465290031	[349]	[339,359,619]	0	hSpCas9	negative selection	6064387
21012858	21012881	17	+	27260156	CAL120	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.2452237380641482	[512]	[985,665,653]	3	hSpCas9	negative selection	6064388
21021204	21021227	17	+	27260156	CAL120	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.07093074137119948	[753]	[1014,749,931]	-1	hSpCas9	negative selection	6064389
21018087	21018110	17	-	27260156	CAL120	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.3495910431160941	[830]	[1607,1347,1044]	5	hSpCas9	negative selection	6128634
21021164	21021187	17	+	27260156	CAL120	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.404579288074562	[1545]	[1707,1582,1112]	-5	hSpCas9	negative selection	6128635
21012819	21012842	17	+	27260156	CAL120	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.07894611118182615	[934]	[1411,1359,946]	1	hSpCas9	negative selection	6128636
21018025	21018048	17	+	27260156	CADOES1	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-0.21567914381739833	[349]	[139,409,288,282]	-4	hSpCas9	negative selection	6185638
21012858	21012881	17	+	27260156	CADOES1	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.09002399229206076	[512]	[459,437,556,578]	1	hSpCas9	negative selection	6185639
21021204	21021227	17	+	27260156	CADOES1	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.3410152149545965	[753]	[568,602,504,536]	-5	hSpCas9	negative selection	6185640
21018087	21018110	17	-	27260156	CADOES1	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	-0.15558839017034243	[830]	[690,817,540,726]	-3	hSpCas9	negative selection	6249885
21021164	21021187	17	+	27260156	CADOES1	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.3972015569625267	[1545]	[1219,989,1261,886]	-6	hSpCas9	negative selection	6249886
21012819	21012842	17	+	27260156	CADOES1	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.13745371451790211	[934]	[720,655,1074,706]	-2	hSpCas9	negative selection	6249887
21018025	21018048	17	+	27260156	EWS502	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.46834810456970305	[349]	[405,432,774,450]	7	hSpCas9	negative selection	6306889
21012858	21012881	17	+	27260156	EWS502	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.16194956479759048	[512]	[611,499,644,681]	3	hSpCas9	negative selection	6306890
21021204	21021227	17	+	27260156	EWS502	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.24534726631065285	[753]	[741,790,1285,1003]	4	hSpCas9	negative selection	6306891
21018087	21018110	17	-	27260156	EWS502	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.5212023678375811	[830]	[1054,1145,1165,1743]	8	hSpCas9	negative selection	6371136
21021164	21021187	17	+	27260156	EWS502	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.13707396481250078	[1545]	[1073,1582,1536,1827]	-2	hSpCas9	negative selection	6371137
21012819	21012842	17	+	27260156	EWS502	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.3595590634412471	[934]	[1021,1179,1605,1310]	6	hSpCas9	negative selection	6371138
21018025	21018048	17	+	27260156	EW8	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-0.05963340870384898	[349]	[288,236,214,357]	-1	hSpCas9	negative selection	6428140
21012858	21012881	17	+	27260156	EW8	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.11589130971433206	[512]	[437,416,504,429]	2	hSpCas9	negative selection	6428141
21021204	21021227	17	+	27260156	EW8	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.10885707781925646	[753]	[845,579,509,369]	-2	hSpCas9	negative selection	6428142
21018087	21018110	17	-	27260156	EW8	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.018711005203282616	[830]	[660,621,652,792]	0	hSpCas9	negative selection	6492387
21021164	21021187	17	+	27260156	EW8	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.45387928704460645	[1545]	[906,793,784,1189]	-7	hSpCas9	negative selection	6492388
21012819	21012842	17	+	27260156	EW8	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.11880997106001512	[934]	[690,545,693,856]	-2	hSpCas9	negative selection	6492389
21018025	21018048	17	+	27260156	CORL105	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.5005449354984388	[349]	[530,501,786,530]	8	hSpCas9	negative selection	6549391
21012858	21012881	17	+	27260156	CORL105	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.42546494111023914	[512]	[669,872,889,799]	7	hSpCas9	negative selection	6549392
21021204	21021227	17	+	27260156	CORL105	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.425698274178515	[753]	[1136,878,1553,1233]	7	hSpCas9	negative selection	6549393
21018087	21018110	17	-	27260156	CORL105	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.37089096059666204	[830]	[1178,1358,1513,1015]	7	hSpCas9	negative selection	6613638
21021164	21021187	17	+	27260156	CORL105	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	0.17840456685147155	[1545]	[2204,2024,1859,2077]	3	hSpCas9	negative selection	6613639
21012819	21012842	17	+	27260156	CORL105	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.2308630773169713	[934]	[1384,1226,1462,1095]	4	hSpCas9	negative selection	6613640
21018025	21018048	17	+	27260156	HS294T	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.4799583705469173	[349]	[84,410,90,165]	6	hSpCas9	negative selection	6670642
21012858	21012881	17	+	27260156	HS294T	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	-0.01475565957836003	[512]	[149,151,200,305]	0	hSpCas9	negative selection	6670643
21021204	21021227	17	+	27260156	HS294T	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.06056654931363992	[753]	[234,274,305,310]	-1	hSpCas9	negative selection	6670644
21018087	21018110	17	-	27260156	HS294T	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.6973910039422305	[830]	[371,724,420,581]	8	hSpCas9	negative selection	6734889
21021164	21021187	17	+	27260156	HS294T	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	0.15754555440354245	[1545]	[918,399,604,736]	2	hSpCas9	negative selection	6734890
21012819	21012842	17	+	27260156	HS294T	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.4470362671987229	[934]	[460,501,543,459]	6	hSpCas9	negative selection	6734891
21018025	21018048	17	+	27260156	HCC44	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.2567745342118798	[349]	[535,450,472,437]	4	hSpCas9	negative selection	6791893
21012858	21012881	17	+	27260156	HCC44	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.5359078381393663	[512]	[1007,713,907,774]	8	hSpCas9	negative selection	6791894
21021204	21021227	17	+	27260156	HCC44	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.348217815254391	[753]	[823,541,953,442]	-5	hSpCas9	negative selection	6791895
21018087	21018110	17	-	27260156	HCC44	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.1894688002623458	[830]	[1009,976,1462,908]	3	hSpCas9	negative selection	6856140
21021164	21021187	17	+	27260156	HCC44	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.36006916869767513	[1545]	[1638,1319,1666,910]	-5	hSpCas9	negative selection	6856141
21012819	21012842	17	+	27260156	HCC44	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.0804437186384539	[934]	[1026,1151,1268,1030]	1	hSpCas9	negative selection	6856142
21018025	21018048	17	+	27260156	G402	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-0.7016518171272159	[349]	[177,320,288,252]	-7	hSpCas9	negative selection	6913144
21012858	21012881	17	+	27260156	G402	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.34470570752633733	[512]	[468,740,965,942]	4	hSpCas9	negative selection	6913145
21021204	21021227	17	+	27260156	G402	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.888356718329437	[753]	[608,699,310,398]	-8	hSpCas9	negative selection	6913146
21018087	21018110	17	-	27260156	G402	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.007345495973408722	[830]	[1646,703,985,817]	0	hSpCas9	negative selection	6977391
21021164	21021187	17	+	27260156	G402	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.43844202560948564	[1545]	[1572,1218,1693,1106]	-5	hSpCas9	negative selection	6977392
21012819	21012842	17	+	27260156	G402	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.2563212811781094	[934]	[1003,566,1455,782]	-3	hSpCas9	negative selection	6977393
21018025	21018048	17	+	27260156	L33	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.009257049275319396	[349]	[331,142,251,327]	0	hSpCas9	negative selection	7034395
21012858	21012881	17	+	27260156	L33	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.4130395510544168	[512]	[592,229,413,918]	8	hSpCas9	negative selection	7034396
21021204	21021227	17	+	27260156	L33	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.26905425553195506	[753]	[893,359,586,927]	6	hSpCas9	negative selection	7034397
21018087	21018110	17	-	27260156	L33	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.31091488641424514	[830]	[997,469,652,940]	6	hSpCas9	negative selection	7098642
21021164	21021187	17	+	27260156	L33	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.23184277570298883	[1545]	[1287,537,781,1419]	-5	hSpCas9	negative selection	7098643
21012819	21012842	17	+	27260156	L33	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.043176720290321824	[934]	[973,355,584,854]	-1	hSpCas9	negative selection	7098644
21018025	21018048	17	+	27260156	K562	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-1.06940262646144	[349]	[72,243,197,82]	-8	hSpCas9	negative selection	7155646
21012858	21012881	17	+	27260156	K562	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.2256512559137247	[512]	[718,348,308,731]	3	hSpCas9	negative selection	7155647
21021204	21021227	17	+	27260156	K562	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-1.343599389239111	[753]	[301,310,218,230]	-8	hSpCas9	negative selection	7155648
21018087	21018110	17	-	27260156	K562	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	-0.21078949620222576	[830]	[558,599,809,575]	-3	hSpCas9	negative selection	7219893
21021164	21021187	17	+	27260156	K562	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.9034951160511766	[1545]	[1080,743,583,569]	-7	hSpCas9	negative selection	7219894
21012819	21012842	17	+	27260156	K562	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.3058156139770897	[934]	[646,519,699,790]	-4	hSpCas9	negative selection	7219895
21018025	21018048	17	+	27260156	HT29	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-0.18241136734703195	[349]	[478,377,315,336]	-4	hSpCas9	negative selection	7276897
21012858	21012881	17	+	27260156	HT29	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.08148446318108502	[512]	[595,664,824,556]	1	hSpCas9	negative selection	7276898
21021204	21021227	17	+	27260156	HT29	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.49648464105096973	[753]	[766,734,589,532]	-7	hSpCas9	negative selection	7276899
21018087	21018110	17	-	27260156	HT29	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	-0.05604038440415682	[830]	[1070,914,938,958]	-1	hSpCas9	negative selection	7341144
21021164	21021187	17	+	27260156	HT29	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.4945435444499855	[1545]	[1415,1499,1396,1066]	-7	hSpCas9	negative selection	7341145
21012819	21012842	17	+	27260156	HT29	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.21682071354040822	[934]	[1001,1267,857,822]	-4	hSpCas9	negative selection	7341146
21018025	21018048	17	+	27260156	MHHES1	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.4874316254518068	[349]	[630,482,639,466]	8	hSpCas9	negative selection	7398148
21012858	21012881	17	+	27260156	MHHES1	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.2839597164898124	[512]	[825,971,451,609]	5	hSpCas9	negative selection	7398149
21021204	21021227	17	+	27260156	MHHES1	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.08914827964996563	[753]	[750,1008,786,672]	-2	hSpCas9	negative selection	7398150
21018087	21018110	17	-	27260156	MHHES1	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.09612384943816854	[830]	[1066,976,880,1046]	1	hSpCas9	negative selection	7462395
21021164	21021187	17	+	27260156	MHHES1	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	0.11369927401796254	[1545]	[2298,2516,1391,1488]	2	hSpCas9	negative selection	7462396
21012819	21012842	17	+	27260156	MHHES1	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.24824919777044596	[934]	[1858,999,1219,1001]	4	hSpCas9	negative selection	7462397
21018025	21018048	17	+	27260156	MEWO	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.0841471899811243	[349]	[309,361,361]	1	hSpCas9	negative selection	7519399
21012858	21012881	17	+	27260156	MEWO	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.09942773691492435	[512]	[756,408,423]	2	hSpCas9	negative selection	7519400
21021204	21021227	17	+	27260156	MEWO	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.09070956665414576	[753]	[981,570,745]	2	hSpCas9	negative selection	7519401
21018087	21018110	17	-	27260156	MEWO	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.10314161666930655	[830]	[938,661,924]	2	hSpCas9	negative selection	7583646
21021164	21021187	17	+	27260156	MEWO	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.1359526768012489	[1545]	[1597,1150,1254]	-3	hSpCas9	negative selection	7583647
21012819	21012842	17	+	27260156	MEWO	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.09377158030431376	[934]	[1150,813,877]	2	hSpCas9	negative selection	7583648
21018025	21018048	17	+	27260156	LNCAPCLONEFGC	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-0.3663182015340693	[349]	[202,227,355,214]	-5	hSpCas9	negative selection	7640650
21012858	21012881	17	+	27260156	LNCAPCLONEFGC	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	-0.11805801125741282	[512]	[429,296,541,468]	-2	hSpCas9	negative selection	7640651
21021204	21021227	17	+	27260156	LNCAPCLONEFGC	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.94375573780043	[753]	[275,327,331,483]	-8	hSpCas9	negative selection	7640652
21018087	21018110	17	-	27260156	LNCAPCLONEFGC	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	-0.3787769128928577	[830]	[455,532,714,636]	-5	hSpCas9	negative selection	7704897
21021164	21021187	17	+	27260156	LNCAPCLONEFGC	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.4293668862142852	[1545]	[876,876,1335,1126]	-6	hSpCas9	negative selection	7704898
21012819	21012842	17	+	27260156	LNCAPCLONEFGC	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.6567826426760883	[934]	[373,496,783,535]	-7	hSpCas9	negative selection	7704899
21018025	21018048	17	+	27260156	PANC0327	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.11427485640175189	[349]	[468,389,283,206]	1	hSpCas9	negative selection	7761901
21012858	21012881	17	+	27260156	PANC0327	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.3204643730992989	[512]	[720,679,424,447]	5	hSpCas9	negative selection	7761902
21021204	21021227	17	+	27260156	PANC0327	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.0008714255076028854	[753]	[743,626,702,614]	0	hSpCas9	negative selection	7761903
21018087	21018110	17	-	27260156	PANC0327	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.19340613745145985	[830]	[803,594,954,1050]	3	hSpCas9	negative selection	7826148
21021164	21021187	17	+	27260156	PANC0327	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.3056456583187326	[1545]	[864,1200,977,1367]	-4	hSpCas9	negative selection	7826149
21012819	21012842	17	+	27260156	PANC0327	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.1516019690010093	[934]	[786,639,865,714]	-2	hSpCas9	negative selection	7826150
21018025	21018048	17	+	27260156	NCIH2009	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.20288174069509993	[349]	[691,347,676]	2	hSpCas9	negative selection	7883152
21012858	21012881	17	+	27260156	NCIH2009	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.466938950914203	[512]	[1070,1220,689]	6	hSpCas9	negative selection	7883153
21021204	21021227	17	+	27260156	NCIH2009	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.05174063621363456	[753]	[1277,1019,1013]	0	hSpCas9	negative selection	7883154
21018087	21018110	17	-	27260156	NCIH2009	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.5104256715865124	[830]	[1962,1316,1745]	7	hSpCas9	negative selection	7947399
21021164	21021187	17	+	27260156	NCIH2009	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.034868957770260334	[1545]	[2628,1589,2214]	0	hSpCas9	negative selection	7947400
21012819	21012842	17	+	27260156	NCIH2009	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.23126836220404123	[934]	[1690,1254,1687]	3	hSpCas9	negative selection	7947401
21018025	21018048	17	+	27260156	NCIH1373	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.08704614503808922	[349]	[222,775,374,54]	0	hSpCas9	negative selection	8004403
21012858	21012881	17	+	27260156	NCIH1373	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.5964448024737712	[512]	[1483,897,624,142]	6	hSpCas9	negative selection	8004404
21021204	21021227	17	+	27260156	NCIH1373	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.30051180585500337	[753]	[505,538,939,194]	-3	hSpCas9	negative selection	8004405
21018087	21018110	17	-	27260156	NCIH1373	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.0016380929200172645	[830]	[1225,1003,778,195]	0	hSpCas9	negative selection	8068650
21021164	21021187	17	+	27260156	NCIH1373	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	0.2119536274296283	[1545]	[2458,1920,1724,524]	2	hSpCas9	negative selection	8068651
21012819	21012842	17	+	27260156	NCIH1373	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.07131477816723775	[934]	[682,1209,1045,254]	0	hSpCas9	negative selection	8068652
21018025	21018048	17	+	27260156	PATU8902	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-1.4791492857523614	[349]	[380,77,168,53]	-8	hSpCas9	negative selection	8125654
21012858	21012881	17	+	27260156	PATU8902	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	-0.6859703922189572	[512]	[475,325,346,675]	-6	hSpCas9	negative selection	8125655
21021204	21021227	17	+	27260156	PATU8902	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-2.173034443027597	[753]	[285,267,57,379]	-9	hSpCas9	negative selection	8125656
21018087	21018110	17	-	27260156	PATU8902	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	-1.0343663430848165	[830]	[597,523,637,463]	-7	hSpCas9	negative selection	8189901
21021164	21021187	17	+	27260156	PATU8902	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.8885761620923875	[1545]	[1182,1318,767,1517]	-7	hSpCas9	negative selection	8189902
21012819	21012842	17	+	27260156	PATU8902	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-1.1268140093606798	[934]	[817,754,364,486]	-7	hSpCas9	negative selection	8189903
21018025	21018048	17	+	27260156	PANC1	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.5139881585171086	[349]	[543,493,349,345]	8	hSpCas9	negative selection	8246905
21012858	21012881	17	+	27260156	PANC1	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.3919430175734061	[512]	[553,773,637,406]	6	hSpCas9	negative selection	8246906
21021204	21021227	17	+	27260156	PANC1	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.3034082761235818	[753]	[764,983,758,725]	5	hSpCas9	negative selection	8246907
21018087	21018110	17	-	27260156	PANC1	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.6694931624308843	[830]	[1209,1139,1158,1029]	9	hSpCas9	negative selection	8311152
21021164	21021187	17	+	27260156	PANC1	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.0025849369743864425	[1545]	[1340,1584,1339,1103]	0	hSpCas9	negative selection	8311153
21012819	21012842	17	+	27260156	PANC1	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.3688495487719545	[934]	[975,1374,1144,753]	6	hSpCas9	negative selection	8311154
21018025	21018048	17	+	27260156	PANC0813	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.0382071033258401	[349]	[304,494,399,473]	0	hSpCas9	negative selection	8368156
21012858	21012881	17	+	27260156	PANC0813	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.11741732160108892	[512]	[675,768,550,620]	2	hSpCas9	negative selection	8368157
21021204	21021227	17	+	27260156	PANC0813	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.5761988160942102	[753]	[703,547,570,563]	-7	hSpCas9	negative selection	8368158
21018087	21018110	17	-	27260156	PANC0813	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	-0.08193979297610088	[830]	[1123,723,931,925]	-1	hSpCas9	negative selection	8432403
21021164	21021187	17	+	27260156	PANC0813	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.35953027052220277	[1545]	[1742,1230,1519,1207]	-5	hSpCas9	negative selection	8432404
21012819	21012842	17	+	27260156	PANC0813	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.2742078261867379	[934]	[850,1179,896,708]	-4	hSpCas9	negative selection	8432405
21018025	21018048	17	+	27260156	RDES	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.38627593892174084	[349]	[535,432,629,492]	6	hSpCas9	negative selection	8489407
21012858	21012881	17	+	27260156	RDES	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.20049925079823544	[512]	[474,644,674,992]	3	hSpCas9	negative selection	8489408
21021204	21021227	17	+	27260156	RDES	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.053817577563977426	[753]	[730,867,778,974]	-1	hSpCas9	negative selection	8489409
21018087	21018110	17	-	27260156	RDES	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.21096352496127324	[830]	[974,1027,1085,1376]	3	hSpCas9	negative selection	8553654
21021164	21021187	17	+	27260156	RDES	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.19495341377230124	[1545]	[1264,1650,1569,1763]	-3	hSpCas9	negative selection	8553655
21012819	21012842	17	+	27260156	RDES	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.12897020268767978	[934]	[926,1187,1271,1365]	2	hSpCas9	negative selection	8553656
21018025	21018048	17	+	27260156	PC3	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.41857910959167655	[349]	[303,386,707,594]	8	hSpCas9	negative selection	8610658
21012858	21012881	17	+	27260156	PC3	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.3509775583045083	[512]	[417,498,1387,637]	7	hSpCas9	negative selection	8610659
21021204	21021227	17	+	27260156	PC3	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.1039501926230666	[753]	[562,667,1246,959]	2	hSpCas9	negative selection	8610660
21018087	21018110	17	-	27260156	PC3	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.26826778686547426	[830]	[539,934,1911,1082]	6	hSpCas9	negative selection	8674905
21021164	21021187	17	+	27260156	PC3	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.22145361520610019	[1545]	[738,1417,2209,1401]	-5	hSpCas9	negative selection	8674906
21012819	21012842	17	+	27260156	PC3	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.22958599601567875	[934]	[702,946,1341,1566]	5	hSpCas9	negative selection	8674907
21018025	21018048	17	+	27260156	PATU8988T	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-0.7355858092826393	[349]	[93,287,282,149]	-8	hSpCas9	negative selection	8731909
21012858	21012881	17	+	27260156	PATU8988T	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	-0.0007206175051970576	[512]	[286,460,655,578]	0	hSpCas9	negative selection	8731910
21021204	21021227	17	+	27260156	PATU8988T	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.43113554752217786	[753]	[483,572,684,409]	-6	hSpCas9	negative selection	8731911
21018087	21018110	17	-	27260156	PATU8988T	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	-0.5104651762534657	[830]	[643,429,482,696]	-7	hSpCas9	negative selection	8796156
21021164	21021187	17	+	27260156	PATU8988T	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.5390729017766351	[1545]	[1241,824,897,1138]	-7	hSpCas9	negative selection	8796157
21012819	21012842	17	+	27260156	PATU8988T	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.7227105610602211	[934]	[553,376,632,613]	-8	hSpCas9	negative selection	8796158
21018025	21018048	17	+	27260156	T47D	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.07167764354851236	[349]	[475,385,423,431]	1	hSpCas9	negative selection	8853160
21012858	21012881	17	+	27260156	T47D	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.21682681863110503	[512]	[760,589,652,786]	4	hSpCas9	negative selection	8853161
21021204	21021227	17	+	27260156	T47D	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.27201897433506483	[753]	[712,705,678,816]	-5	hSpCas9	negative selection	8853162
21018087	21018110	17	-	27260156	T47D	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.06310621488069801	[830]	[1093,897,1006,1057]	1	hSpCas9	negative selection	8917407
21021164	21021187	17	+	27260156	T47D	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.32825200167631685	[1545]	[1395,1272,1427,1661]	-6	hSpCas9	negative selection	8917408
21012819	21012842	17	+	27260156	T47D	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.010942601202566737	[934]	[1115,1099,1007,1099]	0	hSpCas9	negative selection	8917409
21018025	21018048	17	+	27260156	SU8686	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-0.3856299949539857	[349]	[318,267,212,249]	-6	hSpCas9	negative selection	8974411
21012858	21012881	17	+	27260156	SU8686	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.26217769032374655	[512]	[623,515,706,599]	4	hSpCas9	negative selection	8974412
21021204	21021227	17	+	27260156	SU8686	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.45534154901357926	[753]	[433,592,625,529]	-6	hSpCas9	negative selection	8974413
21018087	21018110	17	-	27260156	SU8686	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	-0.3698618048138982	[830]	[638,627,583,704]	-6	hSpCas9	negative selection	9038658
21021164	21021187	17	+	27260156	SU8686	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.5080662205894602	[1545]	[949,1010,1015,1399]	-7	hSpCas9	negative selection	9038659
21012819	21012842	17	+	27260156	SU8686	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.715455798321452	[934]	[471,620,582,584]	-8	hSpCas9	negative selection	9038660
21018025	21018048	17	+	27260156	SKES1	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.2335176466906218	[349]	[402,423,314,487]	5	hSpCas9	negative selection	9095662
21012858	21012881	17	+	27260156	SKES1	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.26870276118599756	[512]	[709,809,527,466]	5	hSpCas9	negative selection	9095663
21021204	21021227	17	+	27260156	SKES1	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.05243869140559343	[753]	[798,866,663,605]	-1	hSpCas9	negative selection	9095664
21018087	21018110	17	-	27260156	SKES1	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.1856757482351471	[830]	[1252,808,959,784]	4	hSpCas9	negative selection	9159909
21021164	21021187	17	+	27260156	SKES1	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.23752365751815918	[1545]	[1324,1555,1232,1155]	-5	hSpCas9	negative selection	9159910
21012819	21012842	17	+	27260156	SKES1	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.057069690326785105	[934]	[1131,994,877,900]	1	hSpCas9	negative selection	9159911
21018025	21018048	17	+	27260156	TOV112D	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	-0.10620763274817252	[349]	[413,399,229,284]	-2	hSpCas9	negative selection	9216913
21012858	21012881	17	+	27260156	TOV112D	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.29659776575428454	[512]	[581,790,791,399]	5	hSpCas9	negative selection	9216914
21021204	21021227	17	+	27260156	TOV112D	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.2645572922835629	[753]	[588,798,639,526]	-5	hSpCas9	negative selection	9216915
21018087	21018110	17	-	27260156	TOV112D	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	-0.08963798120361366	[830]	[876,818,616,829]	-2	hSpCas9	negative selection	9281160
21021164	21021187	17	+	27260156	TOV112D	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.40416017898689627	[1545]	[1022,1578,1260,910]	-7	hSpCas9	negative selection	9281161
21012819	21012842	17	+	27260156	TOV112D	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	-0.10014949814181995	[934]	[809,1096,879,758]	-2	hSpCas9	negative selection	9281162
21018025	21018048	17	+	27260156	TC71	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.05041955925479513	[349]	[313,429,467,337]	1	hSpCas9	negative selection	9338164
21012858	21012881	17	+	27260156	TC71	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.16590362493941968	[512]	[460,768,592,650]	4	hSpCas9	negative selection	9338165
21021204	21021227	17	+	27260156	TC71	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	0.04632133099386826	[753]	[780,795,781,991]	1	hSpCas9	negative selection	9338166
21018087	21018110	17	-	27260156	TC71	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.05133751289130706	[830]	[923,1028,734,1015]	1	hSpCas9	negative selection	9402411
21021164	21021187	17	+	27260156	TC71	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.32294437540477383	[1545]	[1313,1378,1390,1205]	-7	hSpCas9	negative selection	9402412
21012819	21012842	17	+	27260156	TC71	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.054444633417654265	[934]	[844,1031,1221,1063]	1	hSpCas9	negative selection	9402413
21018025	21018048	17	+	27260156	TC32	viability	AGTCCCGCAGAAGTGGCGTGTGG	USP22	ENSG00000124422	0.5060683801197071	[349]	[369,413,471,625]	8	hSpCas9	negative selection	9459415
21012858	21012881	17	+	27260156	TC32	viability	GCAACCCGCCTGTGAAGATCTGG	USP22	ENSG00000124422	0.1559424015085702	[512]	[511,380,739,583]	3	hSpCas9	negative selection	9459416
21021204	21021227	17	+	27260156	TC32	viability	GCCTCCGTACATCAGATCAATGG	USP22	ENSG00000124422	-0.12826457760968646	[753]	[678,406,813,778]	-2	hSpCas9	negative selection	9459417
21018087	21018110	17	-	27260156	TC32	viability	CTGCGTGGGCTGATCAACCTTGG	USP22	ENSG00000124422	0.1772302579838091	[830]	[715,598,1269,1105]	3	hSpCas9	negative selection	9523662
21021164	21021187	17	+	27260156	TC32	viability	CTTTGTCATAGATGTAGTCCTGG	USP22	ENSG00000124422	-0.1263672590124172	[1545]	[1240,935,1660,1643]	-2	hSpCas9	negative selection	9523663
21012819	21012842	17	+	27260156	TC32	viability	CTCTCACTTACTGGCAGACTTGG	USP22	ENSG00000124422	0.2015423614386378	[934]	[741,581,1619,1366]	3	hSpCas9	negative selection	9523664
21015848	21015871	17	-	27869803	HPAFII	viability after 27 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.13830748128075343	[447]	[249,183,NaN]	-1	hSpCas9	negative selection	9559559
21017941	21017964	17	-	27869803	HPAFII	viability after 27 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-4.293691427066829	[77]	[0,2,NaN]	-9	hSpCas9	negative selection	9559560
21019112	21019135	17	-	27869803	HPAFII	viability after 27 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.4902190938434817	[372]	[227,314,NaN]	4	hSpCas9	negative selection	9559561
21021140	21021163	17	-	27869803	HPAFII	viability after 27 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-1.2590640749468422	[429]	[94,93,NaN]	-7	hSpCas9	negative selection	9559562
21028630	21028653	17	-	27869803	HPAFII	viability after 27 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	0.17304820207019816	[322]	[203,180,NaN]	1	hSpCas9	negative selection	9559563
21043609	21043632	17	-	27869803	HPAFII	viability after 27 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	-0.35873647538048364	[250]	[109,96,NaN]	-3	hSpCas9	negative selection	9559564
21015848	21015871	17	-	27869803	HPAFII	viability after 15 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	0.06434662946439229	[447]	[746,351,NaN]	0	hSpCas9	negative selection	9642008
21017941	21017964	17	-	27869803	HPAFII	viability after 15 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.43361878933856546	[77]	[66,58,NaN]	-5	hSpCas9	negative selection	9642009
21019112	21019135	17	-	27869803	HPAFII	viability after 15 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.1320635478866835	[372]	[635,316,NaN]	1	hSpCas9	negative selection	9642010
21021140	21021163	17	-	27869803	HPAFII	viability after 15 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.19355191601309407	[429]	[540,318,NaN]	-2	hSpCas9	negative selection	9642011
21028630	21028653	17	-	27869803	HPAFII	viability after 15 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	0.2568718042449177	[322]	[481,372,NaN]	3	hSpCas9	negative selection	9642012
21043609	21043632	17	-	27869803	HPAFII	viability after 15 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	-0.20754063072076018	[250]	[195,256,NaN]	-2	hSpCas9	negative selection	9642013
21015848	21015871	17	-	27869803	ASPC1	viability after 36 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.0028040116965942774	[883]	[382,258,290]	0	hSpCas9	negative selection	9724457
21017941	21017964	17	-	27869803	ASPC1	viability after 36 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	0.5060668206135042	[211]	[151,142,40]	5	hSpCas9	negative selection	9724458
21019112	21019135	17	-	27869803	ASPC1	viability after 36 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.5156158847589307	[775]	[716,313,209]	5	hSpCas9	negative selection	9724459
21021140	21021163	17	-	27869803	ASPC1	viability after 36 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	0.03522535652493952	[908]	[121,589,253]	0	hSpCas9	negative selection	9724460
21028630	21028653	17	-	27869803	ASPC1	viability after 36 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	0.6090764926363632	[837]	[602,442,333]	6	hSpCas9	negative selection	9724461
21043609	21043632	17	-	27869803	ASPC1	viability after 36 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	0.40796348395476806	[511]	[352,258,135]	4	hSpCas9	negative selection	9724462
21015848	21015871	17	-	27869803	PATU8988S	viability after 35 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.03404298773248915	[879]	[413,277,NaN]	0	hSpCas9	negative selection	9806906
21017941	21017964	17	-	27869803	PATU8988S	viability after 35 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-1.2736440111145642	[176]	[22,35,NaN]	-8	hSpCas9	negative selection	9806907
21019112	21019135	17	-	27869803	PATU8988S	viability after 35 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.4088590029020267	[680]	[422,304,NaN]	4	hSpCas9	negative selection	9806908
21021140	21021163	17	-	27869803	PATU8988S	viability after 35 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.11903535301286672	[967]	[352,364,NaN]	-1	hSpCas9	negative selection	9806909
21028630	21028653	17	-	27869803	PATU8988S	viability after 35 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	0.8141680075453157	[701]	[549,443,NaN]	8	hSpCas9	negative selection	9806910
21043609	21043632	17	-	27869803	PATU8988S	viability after 35 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	0.17599190789251595	[567]	[232,283,NaN]	2	hSpCas9	negative selection	9806911
21015848	21015871	17	-	27869803	PATU8988S	viability after 31 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	-0.41601084981242203	[879]	[229,304,NaN]	-5	hSpCas9	negative selection	9889355
21017941	21017964	17	-	27869803	PATU8988S	viability after 31 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-1.2830445604215146	[176]	[39,14,NaN]	-8	hSpCas9	negative selection	9889356
21019112	21019135	17	-	27869803	PATU8988S	viability after 31 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.5988340381588259	[680]	[467,338,NaN]	7	hSpCas9	negative selection	9889357
21021140	21021163	17	-	27869803	PATU8988S	viability after 31 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	0.06120867124524876	[967]	[363,451,NaN]	0	hSpCas9	negative selection	9889358
21028630	21028653	17	-	27869803	PATU8988S	viability after 31 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	0.9168470165312546	[701]	[531,523,NaN]	8	hSpCas9	negative selection	9889359
21043609	21043632	17	-	27869803	PATU8988S	viability after 31 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	-0.09106057606663831	[567]	[176,257,NaN]	-1	hSpCas9	negative selection	9889360
21015848	21015871	17	-	27869803	HPAFII	viability after 35 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	0.1773596673410045	[447]	[247,265,NaN]	1	hSpCas9	negative selection	9971804
21017941	21017964	17	-	27869803	HPAFII	viability after 35 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-5.3033136658655735	[77]	[0,0,NaN]	-9	hSpCas9	negative selection	9971805
21019112	21019135	17	-	27869803	HPAFII	viability after 35 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.5069958732453511	[372]	[249,288,NaN]	3	hSpCas9	negative selection	9971806
21021140	21021163	17	-	27869803	HPAFII	viability after 35 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-1.021177416723896	[429]	[150,57,NaN]	-5	hSpCas9	negative selection	9971807
21028630	21028653	17	-	27869803	HPAFII	viability after 35 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	0.06791484365963779	[322]	[145,199,NaN]	0	hSpCas9	negative selection	9971808
21043609	21043632	17	-	27869803	HPAFII	viability after 35 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	-2.0827544962663214	[250]	[21,38,NaN]	-8	hSpCas9	negative selection	9971809
21015848	21015871	17	-	27869803	HPAFII	viability after 31 days	CCCGTATAAGTTGCTGCACCTGG	USP22	ENSG00000124422	0.2592250667187501	[447]	[298,302,NaN]	1	hSpCas9	negative selection	10054253
21017941	21017964	17	-	27869803	HPAFII	viability after 31 days	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-5.4520310191869905	[77]	[0,0,NaN]	-9	hSpCas9	negative selection	10054254
21019112	21019135	17	-	27869803	HPAFII	viability after 31 days	TGCTGAAGCACAACCCGAAAAGG	USP22	ENSG00000124422	0.311398661394201	[372]	[220,301,NaN]	2	hSpCas9	negative selection	10054255
21021140	21021163	17	-	27869803	HPAFII	viability after 31 days	CATGGAAATAATCGCCAAGGAGG	USP22	ENSG00000124422	-0.7903310317881335	[429]	[184,89,NaN]	-5	hSpCas9	negative selection	10054256
21028630	21028653	17	-	27869803	HPAFII	viability after 31 days	TCTGTGGCGTCCACCTCAACAGG	USP22	ENSG00000124422	0.37023797020978494	[322]	[162,311,NaN]	2	hSpCas9	negative selection	10054257
21043609	21043632	17	-	27869803	HPAFII	viability after 31 days	AGCCAGGTTACGGCAACCGGGGG	USP22	ENSG00000124422	-0.5963566454720155	[250]	[96,88,NaN]	-4	hSpCas9	negative selection	10054258
21028560	21028583	17	-	28162770	P31FUJ	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	0.26387376388882267	[72]	[102]	3	hSpCas9	negative selection	10262256
21007873	21007896	17	+	28162770	P31FUJ	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	0.6642406052377928	[195]	[364]	7	hSpCas9	negative selection	10262257
21042810	21042833	17	-	28162770	P31FUJ	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	-0.2282439224520742	[315]	[316]	-2	hSpCas9	negative selection	10262258
21042742	21042765	17	-	28162770	P31FUJ	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-0.4472458726353356	[361]	[311]	-4	hSpCas9	negative selection	10262259
21042719	21042742	17	-	28162770	P31FUJ	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	0.9355348001247417	[201]	[453]	9	hSpCas9	negative selection	10262260
21021205	21021228	17	-	28162770	P31FUJ	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.8841861632860576	[366]	[795]	8	hSpCas9	negative selection	10262261
21017941	21017964	17	-	28162770	P31FUJ	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.0935274158122511	[147]	[162]	-1	hSpCas9	negative selection	10262262
21011279	21011302	17	+	28162770	P31FUJ	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	-0.18549648963602205	[29]	[30]	-2	hSpCas9	negative selection	10262263
21011239	21011262	17	+	28162770	P31FUJ	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	0.22176365905110274	[26]	[36]	2	hSpCas9	negative selection	10262264
21011228	21011251	17	+	28162770	P31FUJ	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-0.5889460146396539	[31]	[24]	-5	hSpCas9	negative selection	10262265
21028560	21028583	17	-	28162770	TF1	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10431622
21007873	21007896	17	+	28162770	TF1	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	NaN	[NaN]	[155]	1	hSpCas9	negative selection	10431623
21042810	21042833	17	-	28162770	TF1	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	NaN	[NaN]	[215]	1	hSpCas9	negative selection	10431624
21042742	21042765	17	-	28162770	TF1	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10431625
21042719	21042742	17	-	28162770	TF1	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	NaN	[NaN]	[253]	1	hSpCas9	negative selection	10431626
21021205	21021228	17	-	28162770	TF1	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10431627
21017941	21017964	17	-	28162770	TF1	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	NaN	[NaN]	[94]	1	hSpCas9	negative selection	10431628
21011279	21011302	17	+	28162770	TF1	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10431629
21011239	21011262	17	+	28162770	TF1	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10431630
21011228	21011251	17	+	28162770	TF1	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10431631
21028560	21028583	17	-	28162770	SKM1	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-0.21431912080076554	[20]	[31]	-2	hSpCas9	negative selection	10600988
21007873	21007896	17	+	28162770	SKM1	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	0.640104054913617	[48]	[134]	6	hSpCas9	negative selection	10600989
21042810	21042833	17	-	28162770	SKM1	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	-0.20902482113125265	[84]	[129]	-2	hSpCas9	negative selection	10600990
21042742	21042765	17	-	28162770	SKM1	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-1.05806905625553	[105]	[89]	-6	hSpCas9	negative selection	10600991
21042719	21042742	17	-	28162770	SKM1	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	-1.6026886696175298	[66]	[38]	-8	hSpCas9	negative selection	10600992
21021205	21021228	17	-	28162770	SKM1	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	1.0950846646924015	[93]	[354]	8	hSpCas9	negative selection	10600993
21017941	21017964	17	-	28162770	SKM1	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-1.2090248211312524	[33]	[25]	-7	hSpCas9	negative selection	10600994
21011279	21011302	17	+	28162770	SKM1	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	0.17799830197799427	[4]	[9]	1	hSpCas9	negative selection	10600995
21011239	21011262	17	+	28162770	SKM1	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	0.0524674198941355	[5]	[10]	0	hSpCas9	negative selection	10600996
21011228	21011251	17	+	28162770	SKM1	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-1.143929792909368	[4]	[3]	-7	hSpCas9	negative selection	10600997
21028560	21028583	17	-	28162770	SKM1	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-0.21431912080076554	[20]	[31]	-2	hSpCas9	negative selection	10770354
21007873	21007896	17	+	28162770	SKM1	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	0.640104054913617	[48]	[134]	6	hSpCas9	negative selection	10770355
21042810	21042833	17	-	28162770	SKM1	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	-0.20902482113125265	[84]	[129]	-2	hSpCas9	negative selection	10770356
21042742	21042765	17	-	28162770	SKM1	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-1.05806905625553	[105]	[89]	-6	hSpCas9	negative selection	10770357
21042719	21042742	17	-	28162770	SKM1	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	-1.6026886696175298	[66]	[38]	-8	hSpCas9	negative selection	10770358
21021205	21021228	17	-	28162770	SKM1	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	1.0950846646924015	[93]	[354]	8	hSpCas9	negative selection	10770359
21017941	21017964	17	-	28162770	SKM1	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-1.2090248211312524	[33]	[25]	-7	hSpCas9	negative selection	10770360
21011279	21011302	17	+	28162770	SKM1	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	0.17799830197799427	[4]	[9]	1	hSpCas9	negative selection	10770361
21011239	21011262	17	+	28162770	SKM1	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	0.0524674198941355	[5]	[10]	0	hSpCas9	negative selection	10770362
21011228	21011251	17	+	28162770	SKM1	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-1.143929792909368	[4]	[3]	-7	hSpCas9	negative selection	10770363
21028560	21028583	17	-	28162770	PL21	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-1.3697159938416277	[94]	[15]	-7	hSpCas9	negative selection	10939720
21007873	21007896	17	+	28162770	PL21	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	-0.25184902096241524	[144]	[52]	-2	hSpCas9	negative selection	10939721
21042810	21042833	17	-	28162770	PL21	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	-0.45882346767561294	[299]	[94]	-3	hSpCas9	negative selection	10939722
21042742	21042765	17	-	28162770	PL21	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-0.5836027503463335	[302]	[87]	-4	hSpCas9	negative selection	10939723
21042719	21042742	17	-	28162770	PL21	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	-0.004478105119151754	[241]	[104]	0	hSpCas9	negative selection	10939724
21021205	21021228	17	-	28162770	PL21	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.38874917919655916	[357]	[203]	3	hSpCas9	negative selection	10939725
21017941	21017964	17	-	28162770	PL21	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	0.009456052880210342	[104]	[45]	0	hSpCas9	negative selection	10939726
21011279	21011302	17	+	28162770	PL21	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	0.3521427079343704	[8]	[4]	3	hSpCas9	negative selection	10939727
21011239	21011262	17	+	28162770	PL21	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	0.44114771399311525	[21]	[12]	4	hSpCas9	negative selection	10939728
21011228	21011251	17	+	28162770	PL21	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	1.6151771137681643	[5]	[7]	9	hSpCas9	negative selection	10939729
21028560	21028583	17	-	28162770	P31FUJ	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	0.26387376388882267	[72]	[102]	3	hSpCas9	negative selection	11109086
21007873	21007896	17	+	28162770	P31FUJ	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	0.6642406052377928	[195]	[364]	7	hSpCas9	negative selection	11109087
21042810	21042833	17	-	28162770	P31FUJ	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	-0.2282439224520742	[315]	[316]	-2	hSpCas9	negative selection	11109088
21042742	21042765	17	-	28162770	P31FUJ	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-0.4472458726353356	[361]	[311]	-4	hSpCas9	negative selection	11109089
21042719	21042742	17	-	28162770	P31FUJ	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	0.9355348001247417	[201]	[453]	9	hSpCas9	negative selection	11109090
21021205	21021228	17	-	28162770	P31FUJ	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.8841861632860576	[366]	[795]	8	hSpCas9	negative selection	11109091
21017941	21017964	17	-	28162770	P31FUJ	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.0935274158122511	[147]	[162]	-1	hSpCas9	negative selection	11109092
21011279	21011302	17	+	28162770	P31FUJ	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	-0.18549648963602205	[29]	[30]	-2	hSpCas9	negative selection	11109093
21011239	21011262	17	+	28162770	P31FUJ	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	0.22176365905110274	[26]	[36]	2	hSpCas9	negative selection	11109094
21011228	21011251	17	+	28162770	P31FUJ	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-0.5889460146396539	[31]	[24]	-5	hSpCas9	negative selection	11109095
21028560	21028583	17	-	28162770	OCIAML5	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-0.15162685272290477	[31]	[51]	-1	hSpCas9	negative selection	11278452
21007873	21007896	17	+	28162770	OCIAML5	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	-0.22691498002714197	[117]	[181]	-2	hSpCas9	negative selection	11278453
21042810	21042833	17	-	28162770	OCIAML5	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	-0.25061594735427184	[115]	[175]	-2	hSpCas9	negative selection	11278454
21042742	21042765	17	-	28162770	OCIAML5	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	0.1193642769392319	[152]	[299]	1	hSpCas9	negative selection	11278455
21042719	21042742	17	-	28162770	OCIAML5	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	0.421966833919054	[97]	[236]	3	hSpCas9	negative selection	11278456
21021205	21021228	17	-	28162770	OCIAML5	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.39736872363397546	[150]	[358]	3	hSpCas9	negative selection	11278457
21017941	21017964	17	-	28162770	OCIAML5	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	0.11622456940866499	[68]	[134]	1	hSpCas9	negative selection	11278458
21011279	21011302	17	+	28162770	OCIAML5	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	-0.17399466575135936	[19]	[31]	-1	hSpCas9	negative selection	11278459
21011239	21011262	17	+	28162770	OCIAML5	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	0.029288932637384413	[18]	[34]	0	hSpCas9	negative selection	11278460
21011228	21011251	17	+	28162770	OCIAML5	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-1.4370290715851537	[2]	[1]	-7	hSpCas9	negative selection	11278461
21028560	21028583	17	-	28162770	EOL1	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-0.7705976469010447	[135]	[41]	-5	hSpCas9	negative selection	11447818
21007873	21007896	17	+	28162770	EOL1	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	0.259414922165395	[221]	[139]	2	hSpCas9	negative selection	11447819
21042810	21042833	17	-	28162770	EOL1	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	0.45548439060918	[525]	[379]	4	hSpCas9	negative selection	11447820
21042742	21042765	17	-	28162770	EOL1	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-1.4595957197625256	[615]	[117]	-7	hSpCas9	negative selection	11447821
21042719	21042742	17	-	28162770	EOL1	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	-0.34609981837313447	[303]	[125]	-3	hSpCas9	negative selection	11447822
21021205	21021228	17	-	28162770	EOL1	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.4820909833658509	[601]	[442]	4	hSpCas9	negative selection	11447823
21017941	21017964	17	-	28162770	EOL1	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	0.07655086501558439	[134]	[74]	0	hSpCas9	negative selection	11447824
21011279	21011302	17	+	28162770	EOL1	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	0.09447277301284629	[15]	[8]	0	hSpCas9	negative selection	11447825
21011239	21011262	17	+	28162770	EOL1	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	0.3030593948242646	[19]	[12]	2	hSpCas9	negative selection	11447826
21011228	21011251	17	+	28162770	EOL1	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-2.2978446497659135	[27]	[2]	-8	hSpCas9	negative selection	11447827
21028560	21028583	17	-	28162770	MOLM13	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-2.1279614353193135	[132]	[21]	-7	hSpCas9	negative selection	11617184
21007873	21007896	17	+	28162770	MOLM13	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	-2.4363994188756597	[276]	[36]	-8	hSpCas9	negative selection	11617185
21042810	21042833	17	-	28162770	MOLM13	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	0.5744884476180618	[325]	[350]	4	hSpCas9	negative selection	11617186
21042742	21042765	17	-	28162770	MOLM13	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-0.5436062572932507	[503]	[249]	-3	hSpCas9	negative selection	11617187
21042719	21042742	17	-	28162770	MOLM13	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	-1.925518101762722	[330]	[62]	-7	hSpCas9	negative selection	11617188
21021205	21021228	17	-	28162770	MOLM13	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	-1.8148408256301347	[471]	[96]	-7	hSpCas9	negative selection	11617189
21017941	21017964	17	-	28162770	MOLM13	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-2.3700538603464487	[142]	[19]	-8	hSpCas9	negative selection	11617190
21011279	21011302	17	+	28162770	MOLM13	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	-1.117073119176577	[17]	[5]	-5	hSpCas9	negative selection	11617191
21011239	21011262	17	+	28162770	MOLM13	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	0.808926299379646	[14]	[18]	6	hSpCas9	negative selection	11617192
21011228	21011251	17	+	28162770	MOLM13	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-0.9915422370927187	[21]	[7]	-5	hSpCas9	negative selection	11617193
21028560	21028583	17	-	28162770	HEL	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	0.14797414025077904	[123]	[87]	1	hSpCas9	negative selection	11786550
21007873	21007896	17	+	28162770	HEL	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	0.4167351571115301	[199]	[170]	3	hSpCas9	negative selection	11786551
21042810	21042833	17	-	28162770	HEL	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	0.6824850107931134	[357]	[367]	6	hSpCas9	negative selection	11786552
21042742	21042765	17	-	28162770	HEL	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-0.14642297329127762	[393]	[227]	-1	hSpCas9	negative selection	11786553
21042719	21042742	17	-	28162770	HEL	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	0.22127506356207993	[299]	[223]	1	hSpCas9	negative selection	11786554
21021205	21021228	17	-	28162770	HEL	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.7203762433946229	[415]	[438]	6	hSpCas9	negative selection	11786555
21017941	21017964	17	-	28162770	HEL	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.20085961065707614	[130]	[72]	-1	hSpCas9	negative selection	11786556
21011279	21011302	17	+	28162770	HEL	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	1.2948155285800498	[13]	[21]	9	hSpCas9	negative selection	11786557
21011239	21011262	17	+	28162770	HEL	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	0.057776331279200566	[17]	[11]	0	hSpCas9	negative selection	11786558
21011228	21011251	17	+	28162770	HEL	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-3.6791892628870055	[19]	[0]	-9	hSpCas9	negative selection	11786559
21028560	21028583	17	-	28162770	MV411	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-0.4530021673583171	[64]	[39]	-3	hSpCas9	negative selection	11955916
21007873	21007896	17	+	28162770	MV411	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	-0.8340923347138229	[181]	[85]	-5	hSpCas9	negative selection	11955917
21042810	21042833	17	-	28162770	MV411	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	0.01407401162532429	[307]	[261]	0	hSpCas9	negative selection	11955918
21042742	21042765	17	-	28162770	MV411	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-1.1863834241754843	[334]	[123]	-6	hSpCas9	negative selection	11955919
21042719	21042742	17	-	28162770	MV411	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	0.45689091641172497	[223]	[258]	4	hSpCas9	negative selection	11955920
21021205	21021228	17	-	28162770	MV411	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.9737559007494732	[271]	[449]	8	hSpCas9	negative selection	11955921
21017941	21017964	17	-	28162770	MV411	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-0.9284122846166424	[121]	[53]	-6	hSpCas9	negative selection	11955922
21011279	21011302	17	+	28162770	MV411	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	-0.13107407247095448	[12]	[9]	-1	hSpCas9	negative selection	11955923
21011239	21011262	17	+	28162770	MV411	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	2.2474375507827755	[5]	[23]	9	hSpCas9	negative selection	11955924
21011228	21011251	17	+	28162770	MV411	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-0.07449054410458711	[9]	[7]	0	hSpCas9	negative selection	11955925
21028560	21028583	17	-	28162770	MONOMAC1	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-1.2674261749509517	[41]	[19]	-7	hSpCas9	negative selection	12125282
21007873	21007896	17	+	28162770	MONOMAC1	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	-0.010158712336044207	[93]	[106]	0	hSpCas9	negative selection	12125283
21042810	21042833	17	-	28162770	MONOMAC1	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	-0.8027579079475073	[174]	[114]	-6	hSpCas9	negative selection	12125284
21042742	21042765	17	-	28162770	MONOMAC1	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-1.1970368470595538	[169]	[84]	-7	hSpCas9	negative selection	12125285
21042719	21042742	17	-	28162770	MONOMAC1	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	-0.518964941946916	[109]	[87]	-4	hSpCas9	negative selection	12125286
21021205	21021228	17	-	28162770	MONOMAC1	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.17943707099540207	[217]	[282]	1	hSpCas9	negative selection	12125287
21017941	21017964	17	-	28162770	MONOMAC1	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	0.37486950083615606	[73]	[109]	4	hSpCas9	negative selection	12125288
21011279	21011302	17	+	28162770	MONOMAC1	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	1.5034028710815386	[11]	[38]	9	hSpCas9	negative selection	12125289
21011239	21011262	17	+	28162770	MONOMAC1	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	-0.10392744266807252	[14]	[15]	-1	hSpCas9	negative selection	12125290
21011228	21011251	17	+	28162770	MONOMAC1	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	0.48103505805308355	[4]	[7]	5	hSpCas9	negative selection	12125291
21028560	21028583	17	-	28162770	OCIAML2	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-1.2779847472997656	[13]	[31]	-7	hSpCas9	negative selection	12294648
21007873	21007896	17	+	28162770	OCIAML2	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	-0.15942813694785746	[53]	[267]	-1	hSpCas9	negative selection	12294649
21042810	21042833	17	-	28162770	OCIAML2	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	-0.13434643737772878	[59]	[302]	-1	hSpCas9	negative selection	12294650
21042742	21042765	17	-	28162770	OCIAML2	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-0.800778426934492	[54]	[174]	-5	hSpCas9	negative selection	12294651
21042719	21042742	17	-	28162770	OCIAML2	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	-0.23359062794131194	[41]	[197]	-2	hSpCas9	negative selection	12294652
21021205	21021228	17	-	28162770	OCIAML2	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	1.1410309968697827	[57]	[708]	9	hSpCas9	negative selection	12294653
21017941	21017964	17	-	28162770	OCIAML2	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-1.8242667798568615	[22]	[35]	-8	hSpCas9	negative selection	12294654
21011279	21011302	17	+	28162770	OCIAML2	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	-4.0555923259633175	[2]	[0]	-9	hSpCas9	negative selection	12294655
21011239	21011262	17	+	28162770	OCIAML2	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	-0.2611764596132118	[7]	[36]	-2	hSpCas9	negative selection	12294656
21011228	21011251	17	+	28162770	OCIAML2	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	-3.4706298252421615	[1]	[0]	-9	hSpCas9	negative selection	12294657
21028560	21028583	17	-	28162770	OCIAML3	viability	GCATATTCACGAGCATGCGAAGG	USP22	ENSG00000124422	-2.009045139603007	[23]	[17]	-8	hSpCas9	negative selection	12464014
21007873	21007896	17	+	28162770	OCIAML3	viability	GAGATGAAAACAGGCTACGATGG	USP22	ENSG00000124422	0.5315232417596958	[54]	[239]	5	hSpCas9	negative selection	12464015
21042810	21042833	17	-	28162770	OCIAML3	viability	GTGTCCCGGCCAGAGCCCGAGGG	USP22	ENSG00000124422	-0.009045139603006902	[60]	[182]	0	hSpCas9	negative selection	12464016
21042742	21042765	17	-	28162770	OCIAML3	viability	GCACCTGGGCAGCTTCAAGGTGG	USP22	ENSG00000124422	-0.12293610613099148	[100]	[279]	-1	hSpCas9	negative selection	12464017
21042719	21042742	17	-	28162770	OCIAML3	viability	ACAACTGGAAGCAGAACCTGCGG	USP22	ENSG00000124422	-0.7777195934965514	[45]	[80]	-5	hSpCas9	negative selection	12464018
21021205	21021228	17	-	28162770	OCIAML3	viability	GCCATTGATCTGATGTACGGAGG	USP22	ENSG00000124422	0.49254239163227065	[92]	[394]	4	hSpCas9	negative selection	12464019
21017941	21017964	17	-	28162770	OCIAML3	viability	GATGTCCTCACTGTTTCAGGAGG	USP22	ENSG00000124422	-2.0246419946540257	[30]	[22]	-8	hSpCas9	negative selection	12464020
21011279	21011302	17	+	28162770	OCIAML3	viability	CCAGAAGGGGTCGATGGTGGTGG	USP22	ENSG00000124422	-0.4944719667732489	[6]	[14]	-4	hSpCas9	negative selection	12464021
21011239	21011262	17	+	28162770	OCIAML3	viability	AGAATGGGGTGGAAGAGCCGGGG	USP22	ENSG00000124422	-1.2720795454368008	[7]	[9]	-7	hSpCas9	negative selection	12464022
21011228	21011251	17	+	28162770	OCIAML3	viability	GCTCAGGGGCCAGAATGGGGTGG	USP22	ENSG00000124422	0.46488604872940553	[11]	[49]	4	hSpCas9	negative selection	12464023