| 63504807 | 63504830 | 15 | - | 26472758 | Jiyoye | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | -0.24490131507382018 | [32] | [20] | -2 | hSpCas9 | negative selection | 178442 | 63532667 | 63532690 | 15 | - | 26472758 | Jiyoye | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.4246628082347146 | [163] | [165] | 3 | hSpCas9 | negative selection | 178443 | 63504749 | 63504772 | 15 | - | 26472758 | Jiyoye | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | -0.676888883282601 | [52] | [24] | -5 | hSpCas9 | negative selection | 178444 | 63504807 | 63504830 | 15 | - | 26472758 | KBM7 | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | -1.041238423094692 | [191,134] | [10,59] | -7 | hSpCas9 | negative selection | 369560 | 63532667 | 63532690 | 15 | - | 26472758 | KBM7 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.9633693715421486 | [476,385] | [378,405] | 9 | hSpCas9 | negative selection | 369561 | 63504749 | 63504772 | 15 | - | 26472758 | KBM7 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | 0.5053890883004202 | [128,113] | [71,88] | 5 | hSpCas9 | negative selection | 369562 | 63504807 | 63504830 | 15 | - | 26472758 | Raji | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 1.159850955267735 | [26] | [13] | 8 | hSpCas9 | negative selection | 560678 | 63532667 | 63532690 | 15 | - | 26472758 | Raji | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 1.0416593531507632 | [246] | [117] | 8 | hSpCas9 | negative selection | 560679 | 63504749 | 63504772 | 15 | - | 26472758 | Raji | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | -0.758865075737573 | [174] | [23] | -5 | hSpCas9 | negative selection | 560680 | 63504807 | 63504830 | 15 | - | 26472758 | K562 | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 2.250319329106131 | [60] | [244] | 9 | hSpCas9 | negative selection | 751796 | 63532667 | 63532690 | 15 | - | 26472758 | K562 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.5569622332796076 | [400] | [497] | 4 | hSpCas9 | negative selection | 751797 | 63504749 | 63504772 | 15 | - | 26472758 | K562 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | 0.7244116687860604 | [151] | [211] | 6 | hSpCas9 | negative selection | 751798 | 63504816 | 63504839 | 15 | - | 26627737 | DLD1 | viability | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -0.039424033250433865 | [582] | [107,236,187] | 0 | hSpCas9 | negative selection | 791240 | 63529054 | 63529077 | 15 | + | 26627737 | DLD1 | viability | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -0.34191527119558973 | [82] | [34,0,23] | -4 | hSpCas9 | negative selection | 791241 | 63532667 | 63532690 | 15 | - | 26627737 | DLD1 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 1.075911190108181 | [311] | [194,185,230] | 8 | hSpCas9 | negative selection | 791242 | 63504816 | 63504839 | 15 | - | 26627737 | GBM cells | viability after 5 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -0.38906688807833917 | [314] | [126,130] | -6 | hSpCas9 | negative selection | 873555 | 63529054 | 63529077 | 15 | + | 26627737 | GBM cells | viability after 5 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -0.6512832076747941 | [40] | [18,8] | -8 | hSpCas9 | negative selection | 873556 | 63532667 | 63532690 | 15 | - | 26627737 | GBM cells | viability after 5 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.5189719867021885 | [337] | [133,118] | -7 | hSpCas9 | negative selection | 873557 | 63504816 | 63504839 | 15 | - | 26627737 | GBM cells | viability after 13 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -0.3870057966650308 | [314] | [149,114] | -4 | hSpCas9 | negative selection | 955870 | 63529054 | 63529077 | 15 | + | 26627737 | GBM cells | viability after 13 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -0.2331153840692739 | [40] | [8,26] | -3 | hSpCas9 | negative selection | 955871 | 63532667 | 63532690 | 15 | - | 26627737 | GBM cells | viability after 13 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.5126565309261679 | [337] | [186,80] | -6 | hSpCas9 | negative selection | 955872 | 63504816 | 63504839 | 15 | - | 26627737 | GBM cells | viability after 21 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -0.2759033499662011 | [314] | [144,137] | -3 | hSpCas9 | negative selection | 1038185 | 63529054 | 63529077 | 15 | + | 26627737 | GBM cells | viability after 21 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | 1.3687288015288275 | [40] | [56,57] | 9 | hSpCas9 | negative selection | 1038186 | 63532667 | 63532690 | 15 | - | 26627737 | GBM cells | viability after 21 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -1.0343250585280324 | [337] | [85,92] | -7 | hSpCas9 | negative selection | 1038187 | 63504816 | 63504839 | 15 | - | 26627737 | RPE1 | viability after 9 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -0.08636160692167627 | [549] | [221,84] | 0 | hSpCas9 | negative selection | 1120500 | 63529054 | 63529077 | 15 | + | 26627737 | RPE1 | viability after 9 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -0.8610454414831461 | [323] | [40,74] | -6 | hSpCas9 | negative selection | 1120501 | 63532667 | 63532690 | 15 | - | 26627737 | RPE1 | viability after 9 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 1.5031571868132398 | [514] | [439,478] | 8 | hSpCas9 | negative selection | 1120502 | 63504816 | 63504839 | 15 | - | 26627737 | RPE1 | viability after 12 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -0.10643897797821633 | [549] | [111,163] | 0 | hSpCas9 | negative selection | 1202815 | 63529054 | 63529077 | 15 | + | 26627737 | RPE1 | viability after 12 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -1.6173717006280792 | [323] | [23,32] | -8 | hSpCas9 | negative selection | 1202816 | 63532667 | 63532690 | 15 | - | 26627737 | RPE1 | viability after 12 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 1.5791770740766777 | [514] | [410,415] | 8 | hSpCas9 | negative selection | 1202817 | 63504816 | 63504839 | 15 | - | 26627737 | RPE1 | viability after 15 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | 0.725355101062165 | [549] | [356,160] | 4 | hSpCas9 | negative selection | 1285130 | 63529054 | 63529077 | 15 | + | 26627737 | RPE1 | viability after 15 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -3.325150082024427 | [323] | [0,16] | -9 | hSpCas9 | negative selection | 1285131 | 63532667 | 63532690 | 15 | - | 26627737 | RPE1 | viability after 15 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 1.8059382368060661 | [514] | [571,448] | 8 | hSpCas9 | negative selection | 1285132 | 63504816 | 63504839 | 15 | - | 26627737 | RPE1 | viability after 18 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -1.6774782359018885 | [549] | [28,64] | -7 | hSpCas9 | negative selection | 1367445 | 63529054 | 63529077 | 15 | + | 26627737 | RPE1 | viability after 18 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -0.20802357485801948 | [323] | [95,53] | -1 | hSpCas9 | negative selection | 1367446 | 63532667 | 63532690 | 15 | - | 26627737 | RPE1 | viability after 18 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 1.7681930857437065 | [514] | [499,444] | 8 | hSpCas9 | negative selection | 1367447 | 63504816 | 63504839 | 15 | - | 26627737 | HeLa | viability after 8 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -1.2786732537723886 | [523] | [64,48,156] | -8 | hSpCas9 | negative selection | 1449760 | 63529054 | 63529077 | 15 | + | 26627737 | HeLa | viability after 8 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | 1.294275771972321 | [36] | [94,0,34] | 8 | hSpCas9 | negative selection | 1449761 | 63532667 | 63532690 | 15 | - | 26627737 | HeLa | viability after 8 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.04950962180897256 | [468] | [180,264,182] | 0 | hSpCas9 | negative selection | 1449762 | 63504816 | 63504839 | 15 | - | 26627737 | HeLa | viability after 12 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -0.8378498987296423 | [523] | [63,90,209] | -6 | hSpCas9 | negative selection | 1532075 | 63529054 | 63529077 | 15 | + | 26627737 | HeLa | viability after 12 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | 0.04150041709075358 | [36] | [0,41,0] | 0 | hSpCas9 | negative selection | 1532076 | 63532667 | 63532690 | 15 | - | 26627737 | HeLa | viability after 12 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.35952026319488484 | [468] | [371,159,226] | 3 | hSpCas9 | negative selection | 1532077 | 63504816 | 63504839 | 15 | - | 26627737 | HeLa | viability after 15 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -0.48946171980763653 | [523] | [191,223,29] | -4 | hSpCas9 | negative selection | 1614390 | 63529054 | 63529077 | 15 | + | 26627737 | HeLa | viability after 15 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | 0.02572581499502613 | [36] | [7,35,0] | 0 | hSpCas9 | negative selection | 1614391 | 63532667 | 63532690 | 15 | - | 26627737 | HeLa | viability after 15 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.1323695921320009 | [468] | [195,203,117] | -1 | hSpCas9 | negative selection | 1614392 | 63504816 | 63504839 | 15 | - | 26627737 | HeLa | viability after 18 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -0.5042194888262199 | [523] | [130,178,29] | -4 | hSpCas9 | negative selection | 1696705 | 63529054 | 63529077 | 15 | + | 26627737 | HeLa | viability after 18 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | 0.053753864029773 | [36] | [4,30,0] | 0 | hSpCas9 | negative selection | 1696706 | 63532667 | 63532690 | 15 | - | 26627737 | HeLa | viability after 18 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.13938412150984952 | [468] | [128,169,117] | -1 | hSpCas9 | negative selection | 1696707 | 63504816 | 63504839 | 15 | - | 26627737 | HCT116 | viability after 6 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | 1.0704654832868414 | [523] | [36,247] | 6 | hSpCas9 | negative selection | 1779020 | 63529054 | 63529077 | 15 | + | 26627737 | HCT116 | viability after 6 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -2.6354148919698113 | [64] | [0,1] | -9 | hSpCas9 | negative selection | 1779021 | 63532667 | 63532690 | 15 | - | 26627737 | HCT116 | viability after 6 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.04097248516186558 | [309] | [96,19] | 0 | hSpCas9 | negative selection | 1779022 | 63504816 | 63504839 | 15 | - | 26627737 | HCT116 | viability after 8 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -1.1165928121739996 | [478] | [141,139,83] | -8 | hSpCas9 | negative selection | 1861335 | 63529054 | 63529077 | 15 | + | 26627737 | HCT116 | viability after 8 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -0.48211423153990807 | [99] | [76,0,40] | -5 | hSpCas9 | negative selection | 1861336 | 63532667 | 63532690 | 15 | - | 26627737 | HCT116 | viability after 8 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.12273123242725387 | [400] | [207,204,195] | -1 | hSpCas9 | negative selection | 1861337 | 63504816 | 63504839 | 15 | - | 26627737 | HCT116 | viability after 9 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | 0.07530059992227614 | [523] | [214,93] | 0 | hSpCas9 | negative selection | 1943650 | 63529054 | 63529077 | 15 | + | 26627737 | HCT116 | viability after 9 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -4.117378001674986 | [64] | [0,0] | -9 | hSpCas9 | negative selection | 1943651 | 63532667 | 63532690 | 15 | - | 26627737 | HCT116 | viability after 9 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.590067388340028 | [309] | [218,49] | 4 | hSpCas9 | negative selection | 1943652 | 63504816 | 63504839 | 15 | - | 26627737 | HCT116 | viability after 12 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -1.6555935625629932 | [478] | [88,83,65] | -9 | hSpCas9 | negative selection | 2025965 | 63529054 | 63529077 | 15 | + | 26627737 | HCT116 | viability after 12 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -2.707154298619412 | [99] | [7,1,13] | -9 | hSpCas9 | negative selection | 2025966 | 63532667 | 63532690 | 15 | - | 26627737 | HCT116 | viability after 12 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.6680269754134307 | [400] | [116,162,119] | -6 | hSpCas9 | negative selection | 2025967 | 63504816 | 63504839 | 15 | - | 26627737 | HCT116 | viability after 15 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -1.6881424020990194 | [478] | [128,12,118] | -9 | hSpCas9 | negative selection | 2108280 | 63529054 | 63529077 | 15 | + | 26627737 | HCT116 | viability after 15 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -1.4307248130592638 | [99] | [13,25,22] | -8 | hSpCas9 | negative selection | 2108281 | 63532667 | 63532690 | 15 | - | 26627737 | HCT116 | viability after 15 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.38936301909575705 | [400] | [148,182,191] | -4 | hSpCas9 | negative selection | 2108282 | 63504816 | 63504839 | 15 | - | 26627737 | HCT116 | viability after 18 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -1.2457173005585844 | [478] | [150,83,56] | -8 | hSpCas9 | negative selection | 2190595 | 63529054 | 63529077 | 15 | + | 26627737 | HCT116 | viability after 18 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -2.476332408328358 | [99] | [2,2,20] | -9 | hSpCas9 | negative selection | 2190596 | 63532667 | 63532690 | 15 | - | 26627737 | HCT116 | viability after 18 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.08699448285558015 | [400] | [203,135,285] | 0 | hSpCas9 | negative selection | 2190597 | 63504738 | 63504761 | 15 | - | 24336569 | HL60 | viability | GCTCAGGTGTGGACACTCCATGG | USP3 | ENSG00000140455 | 0.4184844097248753 | [465] | [1317] | 4 | hSpCas9 | negative selection | 2305422 | 63504749 | 63504772 | 15 | - | 24336569 | HL60 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | 0.8374728858916681 | [484] | [1833] | 6 | hSpCas9 | negative selection | 2305423 | 63504754 | 63504777 | 15 | - | 24336569 | HL60 | viability | CAATGCAGACGCTGGAGCTCAGG | USP3 | ENSG00000140455 | 1.466023694673597 | [51] | [303] | 8 | hSpCas9 | negative selection | 2305424 | 63504760 | 63504783 | 15 | + | 24336569 | HL60 | viability | CTCCAGCGTCTGCATTGCTCCGG | USP3 | ENSG00000140455 | -0.18901724178369972 | [173] | [322] | -2 | hSpCas9 | negative selection | 2305425 | 63504808 | 63504831 | 15 | - | 24336569 | HL60 | viability | CGCTGCAGCACCAGGACGACGGG | USP3 | ENSG00000140455 | 1.5221622443572955 | [255] | [1555] | 8 | hSpCas9 | negative selection | 2305426 | 63504816 | 63504839 | 15 | - | 24336569 | HL60 | viability | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -0.019664988390074134 | [753] | [1573] | 0 | hSpCas9 | negative selection | 2305427 | 63532666 | 63532689 | 15 | - | 24336569 | HL60 | viability | AACAAGTCAAACAGACCCAAGGG | USP3 | ENSG00000140455 | 0.39287058233371996 | [857] | [2383] | 3 | hSpCas9 | negative selection | 2305428 | 63532682 | 63532705 | 15 | + | 24336569 | HL60 | viability | ACTTGTTCAAGTGTCCACTGTGG | USP3 | ENSG00000140455 | 1.0493551098158247 | [294] | [1291] | 7 | hSpCas9 | negative selection | 2305429 | 63532696 | 63532719 | 15 | - | 24336569 | HL60 | viability | ATGTCACCTACCTTCCACAGTGG | USP3 | ENSG00000140455 | -0.26719805138649616 | [475] | [836] | -2 | hSpCas9 | negative selection | 2305430 | 63504738 | 63504761 | 15 | - | 24336569 | KBM7 | viability | GCTCAGGTGTGGACACTCCATGG | USP3 | ENSG00000140455 | -1.4526860869819713 | [565] | [563] | -7 | hSpCas9 | negative selection | 2372599 | 63504749 | 63504772 | 15 | - | 24336569 | KBM7 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | -2.691107288031193 | [572] | [241] | -9 | hSpCas9 | negative selection | 2372600 | 63504754 | 63504777 | 15 | - | 24336569 | KBM7 | viability | CAATGCAGACGCTGGAGCTCAGG | USP3 | ENSG00000140455 | 0.6468556053091665 | [84] | [362] | 6 | hSpCas9 | negative selection | 2372601 | 63504760 | 63504783 | 15 | + | 24336569 | KBM7 | viability | CTCCAGCGTCTGCATTGCTCCGG | USP3 | ENSG00000140455 | -0.3212019107793269 | [141] | [309] | -3 | hSpCas9 | negative selection | 2372602 | 63504808 | 63504831 | 15 | - | 24336569 | KBM7 | viability | CGCTGCAGCACCAGGACGACGGG | USP3 | ENSG00000140455 | -0.44199816428558286 | [515] | [1035] | -4 | hSpCas9 | negative selection | 2372603 | 63504816 | 63504839 | 15 | - | 24336569 | KBM7 | viability | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -1.1781363624504972 | [598] | [721] | -7 | hSpCas9 | negative selection | 2372604 | 63532666 | 63532689 | 15 | - | 24336569 | KBM7 | viability | AACAAGTCAAACAGACCCAAGGG | USP3 | ENSG00000140455 | -0.718123404547621 | [885] | [1468] | -5 | hSpCas9 | negative selection | 2372605 | 63532682 | 63532705 | 15 | + | 24336569 | KBM7 | viability | ACTTGTTCAAGTGTCCACTGTGG | USP3 | ENSG00000140455 | -0.759411413700738 | [444] | [716] | -5 | hSpCas9 | negative selection | 2372606 | 63532696 | 63532719 | 15 | - | 24336569 | KBM7 | viability | ATGTCACCTACCTTCCACAGTGG | USP3 | ENSG00000140455 | -2.0939422419341818 | [467] | [298] | -8 | hSpCas9 | negative selection | 2372607 | 63504783 | 63504806 | 15 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GACTCAGCCAAGTTCCCCAACGG | USP3 | ENSG00000140455 | -0.005654407253175064 | [3,3] | [2,2] | 0 | hSpCas9 | positive selection | 3031336 | 63504807 | 63504830 | 15 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 0.6978417074054366 | [2,3] | [1,5] | 9 | hSpCas9 | positive selection | 3031337 | 63504783 | 63504806 | 15 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GACTCAGCCAAGTTCCCCAACGG | USP3 | ENSG00000140455 | -0.027416550930672703 | [3,3] | [4,0] | 0 | hSpCas9 | positive selection | 3099194 | 63504807 | 63504830 | 15 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 0.5627391937475551 | [2,2] | [3,1] | 8 | hSpCas9 | positive selection | 3099195 | 63504782 | 63504805 | 15 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GACTCAGCCAAGTTCCCCAACGG | USP3 | ENSG00000140455 | 1.53448173174506 | [] | [] | 6 | hSpCas9 | negative selection | 3470532 | 63504807 | 63504830 | 15 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 0.719157887864201 | [] | [] | 2 | hSpCas9 | negative selection | 3470533 | 63504782 | 63504805 | 15 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GACTCAGCCAAGTTCCCCAACGG | USP3 | ENSG00000140455 | 4.90847216191314 | [] | [] | 8 | hSpCas9 | negative selection | 3576713 | 63504807 | 63504830 | 15 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 5.4600800246063 | [] | [] | 8 | hSpCas9 | negative selection | 3576714 | 63532666 | 63532689 | 15 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AACAAGTCAAACAGACCCAAGGG | USP3 | ENSG00000140455 | -5.2989696895424 | [] | [] | -5 | hSpCas9 | negative selection | 3576715 | 63504782 | 63504805 | 15 | + | 26780180 | A375 | viability (Avana lentiGuide) | GACTCAGCCAAGTTCCCCAACGG | USP3 | ENSG00000140455 | -0.0723099881634959 | [] | [] | 0 | hSpCas9 | negative selection | 3685372 | 63504807 | 63504830 | 15 | - | 26780180 | A375 | viability (Avana lentiGuide) | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 2.68324473839479 | [] | [] | 3 | hSpCas9 | negative selection | 3685373 | 63532666 | 63532689 | 15 | - | 26780180 | A375 | viability (Avana lentiGuide) | AACAAGTCAAACAGACCCAAGGG | USP3 | ENSG00000140455 | -0.49765078181561 | [] | [] | 0 | hSpCas9 | negative selection | 3685374 | 63504782 | 63504805 | 15 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GACTCAGCCAAGTTCCCCAACGG | USP3 | ENSG00000140455 | 0.3216404423326186 | [4] | [6,5] | 8 | hSpCas9 | positive selection | 3793979 | 63504807 | 63504830 | 15 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 0.1378762163964729 | [3] | [4,4] | 3 | hSpCas9 | positive selection | 3793980 | 63532666 | 63532689 | 15 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AACAAGTCAAACAGACCCAAGGG | USP3 | ENSG00000140455 | -0.42981370728344004 | [4] | [4,1] | -6 | hSpCas9 | positive selection | 3793981 | 63504782 | 63504805 | 15 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GACTCAGCCAAGTTCCCCAACGG | USP3 | ENSG00000140455 | 0.11905154867903071 | [5] | [5,3] | 2 | hSpCas9 | positive selection | 3902586 | 63504807 | 63504830 | 15 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 0.0812152408133053 | [4] | [4,3] | 1 | hSpCas9 | positive selection | 3902587 | 63532666 | 63532689 | 15 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AACAAGTCAAACAGACCCAAGGG | USP3 | ENSG00000140455 | 0.05729172945114082 | [4] | [3,4] | 1 | hSpCas9 | positive selection | 3902588 | 63532691 | 63532713 | 15 | + | 27760321 | OCIAML3 | viability | AGTGTCCACTGTGGAAGGTAGG | USP3 | ENSG00000140455 | -0.31942337129410675 | [520,497] | [268,385] | -3 | hSpCas9 | negative selection | 4452708 | 63532691 | 63532713 | 15 | + | 27760321 | OCIAML2 | viability | AGTGTCCACTGTGGAAGGTAGG | USP3 | ENSG00000140455 | 0.09226709584098691 | [520,497] | [395,497] | 1 | hSpCas9 | negative selection | 4536171 | 63532691 | 63532713 | 15 | + | 27760321 | MV411 | viability | AGTGTCCACTGTGGAAGGTAGG | USP3 | ENSG00000140455 | -1.1386234722757091 | [520,497] | [64,284] | -6 | hSpCas9 | negative selection | 4619634 | 63532691 | 63532713 | 15 | + | 27760321 | HL60 | viability | AGTGTCCACTGTGGAAGGTAGG | USP3 | ENSG00000140455 | 0.4436815907210301 | [520,497] | [429,711] | 5 | hSpCas9 | negative selection | 4703097 | 63532691 | 63532713 | 15 | + | 27760321 | HT1080 | viability | AGTGTCCACTGTGGAAGGTAGG | USP3 | ENSG00000140455 | -0.201366585236611 | [497,388] | [230,68] | -1 | hSpCas9 | negative selection | 4786560 | 63532691 | 63532713 | 15 | + | 27760321 | HT29 | viability after 7 days | AGTGTCCACTGTGGAAGGTAGG | USP3 | ENSG00000140455 | -0.2761788288767274 | [497,388] | [713,367,367] | -4 | hSpCas9 | negative selection | 4870023 | 63532691 | 63532713 | 15 | + | 27760321 | HT29 | viability after 25 days | AGTGTCCACTGTGGAAGGTAGG | USP3 | ENSG00000140455 | -0.0038333437409163174 | [497,388] | [466,383,685] | 0 | hSpCas9 | negative selection | 4953486 | 63532691 | 63532713 | 15 | + | 27760321 | HT29 | viability after 22 days | AGTGTCCACTGTGGAAGGTAGG | USP3 | ENSG00000140455 | -0.3437060714118005 | [497,388] | [280,366,568] | -3 | hSpCas9 | negative selection | 5036949 | 63532691 | 63532713 | 15 | + | 27760321 | HT29 | viability after 19 days | AGTGTCCACTGTGGAAGGTAGG | USP3 | ENSG00000140455 | 0.10010901071761807 | [497,388] | [462,527,627] | 0 | hSpCas9 | negative selection | 5120412 | 63532691 | 63532713 | 15 | + | 27760321 | HT29 | viability after 16 days | AGTGTCCACTGTGGAAGGTAGG | USP3 | ENSG00000140455 | -0.07357794043748059 | [497,388] | [580,275,572] | -1 | hSpCas9 | negative selection | 5203875 | 63532691 | 63532713 | 15 | + | 27760321 | HT29 | viability after 13 days | AGTGTCCACTGTGGAAGGTAGG | USP3 | ENSG00000140455 | 0.02756077073574642 | [497,388] | [317,564,680] | 0 | hSpCas9 | negative selection | 5287338 | 63532691 | 63532713 | 15 | + | 27760321 | HT29 | viability after 10 days | AGTGTCCACTGTGGAAGGTAGG | USP3 | ENSG00000140455 | 0.016190275445071622 | [497,388] | [399,772,513] | 0 | hSpCas9 | negative selection | 5370801 | 63532691 | 63532713 | 15 | + | 27760321 | MOLM13 | viability | AGTGTCCACTGTGGAAGGTAGG | USP3 | ENSG00000140455 | 0.5705143193371559 | [520,497] | [561,312] | 4 | hSpCas9 | negative selection | 5454264 | 63505031 | 63505054 | 15 | + | 27661255 | K562 | viability | GGCCGGGCCAGCGAAGGAGAGGG | USP3 | ENSG00000140455 | -0.17938656904416594 | [508,719] | [480,387] | -5 | dCas9-KRAB | negative selection | 5521818 | 63504623 | 63504646 | 15 | - | 27661255 | K562 | viability | GCCGGGCGCTCGGCCGACGGCGG | USP3 | ENSG00000140455 | -0.12005891321887707 | [586,632] | [511,392] | -4 | dCas9-KRAB | negative selection | 5521819 | 63504657 | 63504680 | 15 | - | 27661255 | K562 | viability | GGAACTCCGGAGGCTCCGTCTGG | USP3 | ENSG00000140455 | 0.0004788173615146718 | [214,246] | [195,173] | 0 | dCas9-KRAB | negative selection | 5521820 | 63505166 | 63505189 | 15 | - | 27661255 | K562 | viability | GGCGACCCCGCAACACGGACGGG | USP3 | ENSG00000140455 | 0.11862041897482029 | [703,769] | [730,558] | 4 | dCas9-KRAB | negative selection | 5521821 | 63504816 | 63504839 | 15 | - | 27869803 | HPAFII | viability after 27 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -0.6726690242466471 | [206] | [82,55,NaN] | -5 | hSpCas9 | negative selection | 9554246 | 63529054 | 63529077 | 15 | + | 27869803 | HPAFII | viability after 27 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -2.28899464036543 | [59] | [6,5,NaN] | -8 | hSpCas9 | negative selection | 9554247 | 63532667 | 63532690 | 15 | - | 27869803 | HPAFII | viability after 27 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.04359997719648778 | [278] | [196,112,NaN] | 0 | hSpCas9 | negative selection | 9554248 | 63504816 | 63504839 | 15 | - | 27869803 | HPAFII | viability after 15 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | 0.1925474791609152 | [206] | [252,254,NaN] | 2 | hSpCas9 | negative selection | 9636695 | 63529054 | 63529077 | 15 | + | 27869803 | HPAFII | viability after 15 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -1.997386836786927 | [59] | [17,14,NaN] | -9 | hSpCas9 | negative selection | 9636696 | 63532667 | 63532690 | 15 | - | 27869803 | HPAFII | viability after 15 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.1012372261543584 | [278] | [460,234,NaN] | 1 | hSpCas9 | negative selection | 9636697 | 63504816 | 63504839 | 15 | - | 27869803 | ASPC1 | viability after 36 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | 1.057035330767539 | [741] | [862,209,566] | 8 | hSpCas9 | negative selection | 9719144 | 63529054 | 63529077 | 15 | + | 27869803 | ASPC1 | viability after 36 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -0.4088042607451903 | [95] | [83,0,2] | -4 | hSpCas9 | negative selection | 9719145 | 63532667 | 63532690 | 15 | - | 27869803 | ASPC1 | viability after 36 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.5139738335105415 | [677] | [351,48,125] | -5 | hSpCas9 | negative selection | 9719146 | 63504816 | 63504839 | 15 | - | 27869803 | PATU8988S | viability after 35 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -0.14708296742532279 | [657] | [161,316,NaN] | -1 | hSpCas9 | negative selection | 9801593 | 63529054 | 63529077 | 15 | + | 27869803 | PATU8988S | viability after 35 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -1.800525108344294 | [81] | [0,17,NaN] | -8 | hSpCas9 | negative selection | 9801594 | 63532667 | 63532690 | 15 | - | 27869803 | PATU8988S | viability after 35 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.1400597720949332 | [582] | [247,177,NaN] | -1 | hSpCas9 | negative selection | 9801595 | 63504816 | 63504839 | 15 | - | 27869803 | PATU8988S | viability after 31 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -0.2235431071196693 | [657] | [185,273,NaN] | -3 | hSpCas9 | negative selection | 9884042 | 63529054 | 63529077 | 15 | + | 27869803 | PATU8988S | viability after 31 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -0.9436219719177403 | [81] | [16,16,NaN] | -7 | hSpCas9 | negative selection | 9884043 | 63532667 | 63532690 | 15 | - | 27869803 | PATU8988S | viability after 31 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.022967376763799938 | [582] | [208,253,NaN] | 0 | hSpCas9 | negative selection | 9884044 | 63504816 | 63504839 | 15 | - | 27869803 | HPAFII | viability after 35 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -1.0897229314656802 | [206] | [52,44,NaN] | -6 | hSpCas9 | negative selection | 9966491 | 63529054 | 63529077 | 15 | + | 27869803 | HPAFII | viability after 35 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -2.153743249777229 | [59] | [11,0,NaN] | -8 | hSpCas9 | negative selection | 9966492 | 63532667 | 63532690 | 15 | - | 27869803 | HPAFII | viability after 35 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.5966332724220679 | [278] | [75,112,NaN] | -4 | hSpCas9 | negative selection | 9966493 | 63504816 | 63504839 | 15 | - | 27869803 | HPAFII | viability after 31 days | GCACTCACCGCTGCAGCACCAGG | USP3 | ENSG00000140455 | -2.832683630544332 | [206] | [11,20,NaN] | -8 | hSpCas9 | negative selection | 10048940 | 63529054 | 63529077 | 15 | + | 27869803 | HPAFII | viability after 31 days | GAGAGTACTGTATGTTGCCCAGG | USP3 | ENSG00000140455 | -2.204211983132899 | [59] | [2,11,NaN] | -8 | hSpCas9 | negative selection | 10048941 | 63532667 | 63532690 | 15 | - | 27869803 | HPAFII | viability after 31 days | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.07012831758506508 | [278] | [183,142,NaN] | 0 | hSpCas9 | negative selection | 10048942 | 63504807 | 63504830 | 15 | - | 28162770 | P31FUJ | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 0.8804084060336126 | [48] | [105] | 8 | hSpCas9 | negative selection | 10262326 | 63532667 | 63532690 | 15 | - | 28162770 | P31FUJ | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.048584486104159 | [278] | [316] | 0 | hSpCas9 | negative selection | 10262327 | 63504749 | 63504772 | 15 | - | 28162770 | P31FUJ | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | 0.6539871851376307 | [52] | [97] | 7 | hSpCas9 | negative selection | 10262328 | 63504807 | 63504830 | 15 | - | 28162770 | TF1 | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | NaN | [NaN] | [26] | 1 | hSpCas9 | negative selection | 10431692 | 63532667 | 63532690 | 15 | - | 28162770 | TF1 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | NaN | [NaN] | [278] | 1 | hSpCas9 | negative selection | 10431693 | 63504749 | 63504772 | 15 | - | 28162770 | TF1 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | NaN | [NaN] | [131] | 1 | hSpCas9 | negative selection | 10431694 | 63504807 | 63504830 | 15 | - | 28162770 | SKM1 | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | -0.1648894115450139 | [25] | [40] | -1 | hSpCas9 | negative selection | 10601058 | 63532667 | 63532690 | 15 | - | 28162770 | SKM1 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.6305105066755012 | [75] | [207] | 6 | hSpCas9 | negative selection | 10601059 | 63504749 | 63504772 | 15 | - | 28162770 | SKM1 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | -0.21793037435314488 | [24] | [37] | -2 | hSpCas9 | negative selection | 10601060 | 63504807 | 63504830 | 15 | - | 28162770 | SKM1 | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | -0.1648894115450139 | [25] | [40] | -1 | hSpCas9 | negative selection | 10770424 | 63532667 | 63532690 | 15 | - | 28162770 | SKM1 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.6305105066755012 | [75] | [207] | 6 | hSpCas9 | negative selection | 10770425 | 63504749 | 63504772 | 15 | - | 28162770 | SKM1 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | -0.21793037435314488 | [24] | [37] | -2 | hSpCas9 | negative selection | 10770426 | 63504807 | 63504830 | 15 | - | 28162770 | PL21 | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | -1.1733187810381243 | [56] | [10] | -7 | hSpCas9 | negative selection | 10939790 | 63532667 | 63532690 | 15 | - | 28162770 | PL21 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.7998558819005029 | [226] | [171] | 6 | hSpCas9 | negative selection | 10939791 | 63504749 | 63504772 | 15 | - | 28162770 | PL21 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | -2.7998603855106805 | [47] | [2] | -9 | hSpCas9 | negative selection | 10939792 | 63504807 | 63504830 | 15 | - | 28162770 | P31FUJ | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 0.8804084060336126 | [48] | [105] | 8 | hSpCas9 | negative selection | 11109156 | 63532667 | 63532690 | 15 | - | 28162770 | P31FUJ | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.048584486104159 | [278] | [316] | 0 | hSpCas9 | negative selection | 11109157 | 63504749 | 63504772 | 15 | - | 28162770 | P31FUJ | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | 0.6539871851376307 | [52] | [97] | 7 | hSpCas9 | negative selection | 11109158 | 63504807 | 63504830 | 15 | - | 28162770 | OCIAML5 | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 0.38579725923489083 | [52] | [124] | 3 | hSpCas9 | negative selection | 11278522 | 63532667 | 63532690 | 15 | - | 28162770 | OCIAML5 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.7704593428136427 | [138] | [427] | 6 | hSpCas9 | negative selection | 11278523 | 63504749 | 63504772 | 15 | - | 28162770 | OCIAML5 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | -1.977597452947856 | [47] | [21] | -8 | hSpCas9 | negative selection | 11278524 | 63504807 | 63504830 | 15 | - | 28162770 | EOL1 | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | -0.4212270652711958 | [121] | [47] | -3 | hSpCas9 | negative selection | 11447888 | 63532667 | 63532690 | 15 | - | 28162770 | EOL1 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.4135168881668059 | [522] | [366] | 4 | hSpCas9 | negative selection | 11447889 | 63504749 | 63504772 | 15 | - | 28162770 | EOL1 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | 0.3204764479016735 | [75] | [49] | 3 | hSpCas9 | negative selection | 11447890 | 63504807 | 63504830 | 15 | - | 28162770 | MOLM13 | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | -2.467015590233536 | [129] | [16] | -8 | hSpCas9 | negative selection | 11617254 | 63532667 | 63532690 | 15 | - | 28162770 | MOLM13 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 1.0943440111841984 | [376] | [581] | 8 | hSpCas9 | negative selection | 11617255 | 63504749 | 63504772 | 15 | - | 28162770 | MOLM13 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | 1.8025847725058193 | [89] | [226] | 9 | hSpCas9 | negative selection | 11617256 | 63504807 | 63504830 | 15 | - | 28162770 | HEL | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 1.790169195655583 | [78] | [174] | 9 | hSpCas9 | negative selection | 11786620 | 63532667 | 63532690 | 15 | - | 28162770 | HEL | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 0.6103173543079795 | [314] | [307] | 5 | hSpCas9 | negative selection | 11786621 | 63504749 | 63504772 | 15 | - | 28162770 | HEL | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | -0.24478643874123063 | [73] | [39] | -2 | hSpCas9 | negative selection | 11786622 | 63504807 | 63504830 | 15 | - | 28162770 | MV411 | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | -0.6668325751913409 | [48] | [25] | -5 | hSpCas9 | negative selection | 11955986 | 63532667 | 63532690 | 15 | - | 28162770 | MV411 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.011198391153501741 | [261] | [218] | 0 | hSpCas9 | negative selection | 11955987 | 63504749 | 63504772 | 15 | - | 28162770 | MV411 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | 0.09131834886549317 | [38] | [34] | 0 | hSpCas9 | negative selection | 11955988 | 63504807 | 63504830 | 15 | - | 28162770 | MONOMAC1 | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 1.556607488253283 | [42] | [144] | 9 | hSpCas9 | negative selection | 12125352 | 63532667 | 63532690 | 15 | - | 28162770 | MONOMAC1 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.17865831774469906 | [155] | [157] | -1 | hSpCas9 | negative selection | 12125353 | 63504749 | 63504772 | 15 | - | 28162770 | MONOMAC1 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | -1.7819993477807101 | [47] | [15] | -8 | hSpCas9 | negative selection | 12125354 | 63504807 | 63504830 | 15 | - | 28162770 | OCIAML2 | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | -0.7098174891215872 | [17] | [60] | -5 | hSpCas9 | negative selection | 12294718 | 63532667 | 63532690 | 15 | - | 28162770 | OCIAML2 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | -0.07208044875188635 | [54] | [289] | 0 | hSpCas9 | negative selection | 12294719 | 63504749 | 63504772 | 15 | - | 28162770 | OCIAML2 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | -1.2335906279413118 | [13] | [32] | -7 | hSpCas9 | negative selection | 12294720 | 63504807 | 63504830 | 15 | - | 28162770 | OCIAML3 | viability | GCTGCAGCACCAGGACGACGGGG | USP3 | ENSG00000140455 | 1.6623321129356226 | [8] | [85] | 9 | hSpCas9 | negative selection | 12464084 | 63532667 | 63532690 | 15 | - | 28162770 | OCIAML3 | viability | GAACAAGTCAAACAGACCCAAGG | USP3 | ENSG00000140455 | 1.038755581198696 | [93] | [582] | 8 | hSpCas9 | negative selection | 12464085 | 63504749 | 63504772 | 15 | - | 28162770 | OCIAML3 | viability | CAGACGCTGGAGCTCAGGTGTGG | USP3 | ENSG00000140455 | 0.607626220845487 | [9] | [45] | 5 | hSpCas9 | negative selection | 12464086 |