Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5976
• Symbol:Upf1
• Description:UPF1 RNA helicase and ATPase

DataSource: http://genomecrispr.dkfz.de/#!/results/Upf1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
18850763	18850786	19	-	26472758	Jiyoye	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-2.9415527727252044	[162]	[15]	-9	hSpCas9	negative selection	177761
18855014	18855037	19	-	26472758	Jiyoye	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-2.914752713381489	[9]	[0]	-9	hSpCas9	negative selection	177762
18854942	18854965	19	+	26472758	Jiyoye	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-0.4817933061053825	[49]	[26]	-3	hSpCas9	negative selection	177763
18850112	18850135	19	+	26472758	Jiyoye	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-1.7466299545731618	[88]	[19]	-8	hSpCas9	negative selection	177764
18850793	18850816	19	-	26472758	Jiyoye	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-0.9483052730925156	[86]	[33]	-6	hSpCas9	negative selection	177765
18850835	18850858	19	+	26472758	Jiyoye	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-1.8596111591890279	[153]	[31]	-8	hSpCas9	negative selection	177766
18852154	18852177	19	+	26472758	Jiyoye	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-1.1777871192152827	[137]	[45]	-7	hSpCas9	negative selection	177767
18853249	18853272	19	+	26472758	Jiyoye	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-5.084677714823801	[44]	[0]	-9	hSpCas9	negative selection	177768
18854656	18854679	19	+	26472758	Jiyoye	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-1.848325351642513	[190]	[39]	-8	hSpCas9	negative selection	177769
18854917	18854940	19	-	26472758	Jiyoye	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-5.762749619936439	[71]	[0]	-9	hSpCas9	negative selection	177770
18850763	18850786	19	-	26472758	KBM7	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-2.0520961154776987	[679,554]	[104,37]	-8	hSpCas9	negative selection	368879
18855014	18855037	19	-	26472758	KBM7	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-2.817705914218136	[31,0]	[0,0]	-9	hSpCas9	negative selection	368880
18854942	18854965	19	+	26472758	KBM7	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-1.2671718218573929	[665,500]	[180,51]	-7	hSpCas9	negative selection	368881
18850112	18850135	19	+	26472758	KBM7	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-1.565404022866532	[481,384]	[69,66]	-8	hSpCas9	negative selection	368882
18850793	18850816	19	-	26472758	KBM7	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-2.2797744728388434	[662,340]	[51,42]	-8	hSpCas9	negative selection	368883
18850835	18850858	19	+	26472758	KBM7	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-0.5573420608717258	[852,532]	[230,204]	-5	hSpCas9	negative selection	368884
18852154	18852177	19	+	26472758	KBM7	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-1.8002297893858172	[441,377]	[98,15]	-8	hSpCas9	negative selection	368885
18853249	18853272	19	+	26472758	KBM7	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-2.2659146590997876	[235,345]	[35,22]	-8	hSpCas9	negative selection	368886
18854656	18854679	19	+	26472758	KBM7	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-0.8562026753261257	[442,569]	[154,114]	-6	hSpCas9	negative selection	368887
18854917	18854940	19	-	26472758	KBM7	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-2.2537569837730436	[251,187]	[21,20]	-8	hSpCas9	negative selection	368888
18850763	18850786	19	-	26472758	Raji	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-2.4286693648666104	[231]	[9]	-9	hSpCas9	negative selection	559997
18855014	18855037	19	-	26472758	Raji	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-1.5930561827674934	[12]	[0]	-8	hSpCas9	negative selection	559998
18854942	18854965	19	+	26472758	Raji	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-1.4775789653475568	[191]	[15]	-8	hSpCas9	negative selection	559999
18850112	18850135	19	+	26472758	Raji	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-2.6205369191895995	[105]	[3]	-9	hSpCas9	negative selection	560000
18850793	18850816	19	-	26472758	Raji	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-2.4603009739157216	[165]	[6]	-9	hSpCas9	negative selection	560001
18850835	18850858	19	+	26472758	Raji	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-2.6022747127968713	[313]	[11]	-9	hSpCas9	negative selection	560002
18852154	18852177	19	+	26472758	Raji	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-0.32433270505187467	[231]	[42]	-3	hSpCas9	negative selection	560003
18853249	18853272	19	+	26472758	Raji	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-2.6022747127968713	[156]	[5]	-9	hSpCas9	negative selection	560004
18854656	18854679	19	+	26472758	Raji	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-2.970618976627674	[303]	[8]	-9	hSpCas9	negative selection	560005
18854917	18854940	19	-	26472758	Raji	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-4.492529306813529	[96]	[0]	-9	hSpCas9	negative selection	560006
18850763	18850786	19	-	26472758	K562	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-3.0335660196333185	[484]	[49]	-8	hSpCas9	negative selection	751115
18855014	18855037	19	-	26472758	K562	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-3.9255062737758646	[17]	[0]	-9	hSpCas9	negative selection	751116
18854942	18854965	19	+	26472758	K562	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-0.5755638027189066	[458]	[259]	-4	hSpCas9	negative selection	751117
18850112	18850135	19	+	26472758	K562	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-2.760875572003066	[272]	[33]	-8	hSpCas9	negative selection	751118
18850793	18850816	19	-	26472758	K562	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-5.440524654151478	[462]	[8]	-9	hSpCas9	negative selection	751119
18850835	18850858	19	+	26472758	K562	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-0.6657436238953104	[606]	[322]	-4	hSpCas9	negative selection	751120
18852154	18852177	19	+	26472758	K562	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-0.9361535179753738	[339]	[149]	-5	hSpCas9	negative selection	751121
18853249	18853272	19	+	26472758	K562	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-6.945405831213571	[291]	[1]	-9	hSpCas9	negative selection	751122
18854656	18854679	19	+	26472758	K562	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-2.3670159844159	[329]	[53]	-8	hSpCas9	negative selection	751123
18854917	18854940	19	-	26472758	K562	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-4.317823696554626	[188]	[7]	-9	hSpCas9	negative selection	751124
18832197	18832220	19	+	26627737	DLD1	viability	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-3.7194627842036962	[2640]	[35,59,87]	-9	hSpCas9	negative selection	803503
18846039	18846062	19	-	26627737	DLD1	viability	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.0868487417990032	[580]	[151,237,131]	-1	hSpCas9	negative selection	803504
18847767	18847790	19	-	26627737	DLD1	viability	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-1.7967828638603756	[112]	[0,25,4]	-8	hSpCas9	negative selection	803505
18850108	18850131	19	+	26627737	DLD1	viability	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-3.188166897701313	[985]	[78,1,20]	-9	hSpCas9	negative selection	803506
18850772	18850795	19	-	26627737	DLD1	viability	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-2.185253023143478	[320]	[12,27,24]	-9	hSpCas9	negative selection	803507
18852246	18852269	19	-	26627737	DLD1	viability	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-3.6483494527304168	[707]	[1,0,44]	-9	hSpCas9	negative selection	803508
18832197	18832220	19	+	26627737	GBM cells	viability after 5 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-2.2134004033865313	[1214]	[183,96]	-9	hSpCas9	negative selection	885818
18846039	18846062	19	-	26627737	GBM cells	viability after 5 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	0.013313247622771973	[411]	[251,193]	0	hSpCas9	negative selection	885819
18847767	18847790	19	-	26627737	GBM cells	viability after 5 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-4.78291016508806	[76]	[0,1]	-9	hSpCas9	negative selection	885820
18850108	18850131	19	+	26627737	GBM cells	viability after 5 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-0.1092140059977148	[355]	[168,184]	-2	hSpCas9	negative selection	885821
18850772	18850795	19	-	26627737	GBM cells	viability after 5 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-1.3312059084753731	[311]	[65,66]	-9	hSpCas9	negative selection	885822
18852246	18852269	19	-	26627737	GBM cells	viability after 5 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-2.6993454484489288	[326]	[35,17]	-9	hSpCas9	negative selection	885823
18832197	18832220	19	+	26627737	GBM cells	viability after 13 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-2.6588018338137385	[1214]	[126,85]	-9	hSpCas9	negative selection	968133
18846039	18846062	19	-	26627737	GBM cells	viability after 13 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.084706605677622	[411]	[287,147]	-1	hSpCas9	negative selection	968134
18847767	18847790	19	-	26627737	GBM cells	viability after 13 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-5.384683417116454	[76]	[0,0]	-9	hSpCas9	negative selection	968135
18850108	18850131	19	+	26627737	GBM cells	viability after 13 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-1.2171856742254321	[355]	[108,61]	-8	hSpCas9	negative selection	968136
18850772	18850795	19	-	26627737	GBM cells	viability after 13 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-2.1895515652357136	[311]	[51,24]	-9	hSpCas9	negative selection	968137
18852246	18852269	19	-	26627737	GBM cells	viability after 13 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-3.6426271643342014	[326]	[11,15]	-9	hSpCas9	negative selection	968138
18832197	18832220	19	+	26627737	GBM cells	viability after 21 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-3.536714104215778	[1214]	[47,64]	-9	hSpCas9	negative selection	1050448
18846039	18846062	19	-	26627737	GBM cells	viability after 21 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.5943248701394274	[411]	[153,142]	-5	hSpCas9	negative selection	1050449
18847767	18847790	19	-	26627737	GBM cells	viability after 21 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-5.386553241079243	[76]	[0,0]	-9	hSpCas9	negative selection	1050450
18850108	18850131	19	+	26627737	GBM cells	viability after 21 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-2.971659275483403	[355]	[20,27]	-9	hSpCas9	negative selection	1050451
18850772	18850795	19	-	26627737	GBM cells	viability after 21 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-3.8567322945505476	[311]	[6,15]	-9	hSpCas9	negative selection	1050452
18852246	18852269	19	-	26627737	GBM cells	viability after 21 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-6.909484186710909	[326]	[1,0]	-9	hSpCas9	negative selection	1050453
18832197	18832220	19	+	26627737	RPE1	viability after 9 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-3.786829623754878	[6463]	[174,109]	-9	hSpCas9	negative selection	1132763
18846039	18846062	19	-	26627737	RPE1	viability after 9 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-1.1115111385524103	[1917]	[166,420]	-7	hSpCas9	negative selection	1132764
18847767	18847790	19	-	26627737	RPE1	viability after 9 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-3.2457690307560076	[200]	[10,0]	-9	hSpCas9	negative selection	1132765
18850108	18850131	19	+	26627737	RPE1	viability after 9 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-2.559372674515926	[715]	[20,59]	-9	hSpCas9	negative selection	1132766
18850772	18850795	19	-	26627737	RPE1	viability after 9 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-1.6877403393637596	[1157]	[129,89]	-8	hSpCas9	negative selection	1132767
18852246	18852269	19	-	26627737	RPE1	viability after 9 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-2.922924125654607	[506]	[16,25]	-9	hSpCas9	negative selection	1132768
18832197	18832220	19	+	26627737	RPE1	viability after 12 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-4.445333681307074	[6463]	[86,71]	-9	hSpCas9	negative selection	1215078
18846039	18846062	19	-	26627737	RPE1	viability after 12 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.6575160353562057	[1917]	[315,337]	-4	hSpCas9	negative selection	1215079
18847767	18847790	19	-	26627737	RPE1	viability after 12 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-2.1326792373616588	[200]	[22,0]	-8	hSpCas9	negative selection	1215080
18850108	18850131	19	+	26627737	RPE1	viability after 12 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-2.0010253922809413	[715]	[32,63]	-8	hSpCas9	negative selection	1215081
18850772	18850795	19	-	26627737	RPE1	viability after 12 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-2.234417994153575	[1157]	[52,79]	-8	hSpCas9	negative selection	1215082
18852246	18852269	19	-	26627737	RPE1	viability after 12 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-4.6644246905975315	[506]	[0,9]	-9	hSpCas9	negative selection	1215083
18832197	18832220	19	+	26627737	RPE1	viability after 15 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-3.530143121322692	[6463]	[226,91]	-9	hSpCas9	negative selection	1297393
18846039	18846062	19	-	26627737	RPE1	viability after 15 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.1703019241913255	[1917]	[529,435]	-1	hSpCas9	negative selection	1297394
18847767	18847790	19	-	26627737	RPE1	viability after 15 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-1.1821862983687228	[200]	[49,0]	-6	hSpCas9	negative selection	1297395
18850108	18850131	19	+	26627737	RPE1	viability after 15 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-1.2838456184606821	[715]	[100,65]	-7	hSpCas9	negative selection	1297396
18850772	18850795	19	-	26627737	RPE1	viability after 15 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-2.68734716776183	[1157]	[58,42]	-9	hSpCas9	negative selection	1297397
18852246	18852269	19	-	26627737	RPE1	viability after 15 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-7.164093063131446	[506]	[0,0]	-9	hSpCas9	negative selection	1297398
18832197	18832220	19	+	26627737	RPE1	viability after 18 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-5.17619247039518	[6463]	[69,24]	-9	hSpCas9	negative selection	1379708
18846039	18846062	19	-	26627737	RPE1	viability after 18 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.8913768880994829	[1917]	[221,339]	-5	hSpCas9	negative selection	1379709
18847767	18847790	19	-	26627737	RPE1	viability after 18 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-1.5469492068346251	[200]	[34,0]	-7	hSpCas9	negative selection	1379710
18850108	18850131	19	+	26627737	RPE1	viability after 18 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-2.4912824473839605	[715]	[44,22]	-8	hSpCas9	negative selection	1379711
18850772	18850795	19	-	26627737	RPE1	viability after 18 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-2.4985807956975012	[1157]	[63,45]	-8	hSpCas9	negative selection	1379712
18852246	18852269	19	-	26627737	RPE1	viability after 18 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-7.096173676902598	[506]	[0,0]	-9	hSpCas9	negative selection	1379713
18832197	18832220	19	+	26627737	HeLa	viability after 8 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-1.9970798179471227	[2165]	[347,297,96]	-9	hSpCas9	negative selection	1462023
18846039	18846062	19	-	26627737	HeLa	viability after 8 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.362030000766778	[570]	[193,205,180]	-4	hSpCas9	negative selection	1462024
18847767	18847790	19	-	26627737	HeLa	viability after 8 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-3.8244943631793866	[174]	[16,0,0]	-9	hSpCas9	negative selection	1462025
18850108	18850131	19	+	26627737	HeLa	viability after 8 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	0.10726546532053782	[138]	[71,89,36]	1	hSpCas9	negative selection	1462026
18850772	18850795	19	-	26627737	HeLa	viability after 8 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-0.8805076269146839	[327]	[91,54,87]	-7	hSpCas9	negative selection	1462027
18852246	18852269	19	-	26627737	HeLa	viability after 8 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-3.353143049511142	[752]	[93,15,1]	-9	hSpCas9	negative selection	1462028
18832197	18832220	19	+	26627737	HeLa	viability after 12 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-0.9378136273738209	[2165]	[909,322,196]	-7	hSpCas9	negative selection	1544338
18846039	18846062	19	-	26627737	HeLa	viability after 12 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.10942683045801405	[570]	[104,349,183]	-1	hSpCas9	negative selection	1544339
18847767	18847790	19	-	26627737	HeLa	viability after 12 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-1.700501299116433	[174]	[21,0,45]	-9	hSpCas9	negative selection	1544340
18850108	18850131	19	+	26627737	HeLa	viability after 12 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	1.8021665726036287	[138]	[283,109,218]	9	hSpCas9	negative selection	1544341
18850772	18850795	19	-	26627737	HeLa	viability after 12 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-2.423441218957841	[327]	[7,46,17]	-9	hSpCas9	negative selection	1544342
18852246	18852269	19	-	26627737	HeLa	viability after 12 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-2.860215692510964	[752]	[3,46,75]	-9	hSpCas9	negative selection	1544343
18832197	18832220	19	+	26627737	HeLa	viability after 15 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-1.8368690216995385	[2165]	[420,133,177]	-9	hSpCas9	negative selection	1626653
18846039	18846062	19	-	26627737	HeLa	viability after 15 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.00857128513790184	[570]	[315,182,189]	0	hSpCas9	negative selection	1626654
18847767	18847790	19	-	26627737	HeLa	viability after 15 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-2.1270459962760433	[174]	[38,0,7]	-9	hSpCas9	negative selection	1626655
18850108	18850131	19	+	26627737	HeLa	viability after 15 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	0.9198508064943604	[138]	[118,58,145]	7	hSpCas9	negative selection	1626656
18850772	18850795	19	-	26627737	HeLa	viability after 15 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-2.208161636600652	[327]	[47,26,9]	-9	hSpCas9	negative selection	1626657
18852246	18852269	19	-	26627737	HeLa	viability after 15 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-3.4946370035603946	[752]	[0,76,1]	-9	hSpCas9	negative selection	1626658
18832197	18832220	19	+	26627737	HeLa	viability after 18 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-1.7557839722640138	[2165]	[306,114,177]	-9	hSpCas9	negative selection	1708968
18846039	18846062	19	-	26627737	HeLa	viability after 18 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	0.05100863436825609	[570]	[232,148,189]	0	hSpCas9	negative selection	1708969
18847767	18847790	19	-	26627737	HeLa	viability after 18 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-2.376111553703565	[174]	[20,0,7]	-9	hSpCas9	negative selection	1708970
18850108	18850131	19	+	26627737	HeLa	viability after 18 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	0.8853001577140777	[138]	[77,44,145]	6	hSpCas9	negative selection	1708971
18850772	18850795	19	-	26627737	HeLa	viability after 18 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-2.1256568163543865	[327]	[34,22,9]	-9	hSpCas9	negative selection	1708972
18852246	18852269	19	-	26627737	HeLa	viability after 18 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-3.5022203472109035	[752]	[0,62,1]	-9	hSpCas9	negative selection	1708973
18832197	18832220	19	+	26627737	HCT116	viability after 6 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-1.9868565920430787	[3035]	[316,11]	-8	hSpCas9	negative selection	1791283
18846039	18846062	19	-	26627737	HCT116	viability after 6 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	0.15426472095391233	[605]	[125,94]	0	hSpCas9	negative selection	1791284
18847767	18847790	19	-	26627737	HCT116	viability after 6 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-5.688291747430516	[327]	[0,0]	-9	hSpCas9	negative selection	1791285
18850108	18850131	19	+	26627737	HCT116	viability after 6 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-0.013410222044293651	[469]	[185,10]	0	hSpCas9	negative selection	1791286
18850772	18850795	19	-	26627737	HCT116	viability after 6 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-1.1742265489479657	[1041]	[11,105]	-6	hSpCas9	negative selection	1791287
18852246	18852269	19	-	26627737	HCT116	viability after 6 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-6.485557851864536	[569]	[0,0]	-9	hSpCas9	negative selection	1791288
18832197	18832220	19	+	26627737	HCT116	viability after 8 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-2.728314948611454	[1386]	[95,80,167]	-9	hSpCas9	negative selection	1873598
18846039	18846062	19	-	26627737	HCT116	viability after 8 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.13796923769937858	[364]	[130,198,216]	-1	hSpCas9	negative selection	1873599
18847767	18847790	19	-	26627737	HCT116	viability after 8 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-4.499967353868048	[67]	[2,0,0]	-9	hSpCas9	negative selection	1873600
18850108	18850131	19	+	26627737	HCT116	viability after 8 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-1.0441899838128736	[359]	[107,101,78]	-8	hSpCas9	negative selection	1873601
18850772	18850795	19	-	26627737	HCT116	viability after 8 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-0.6628353855246507	[260]	[114,70,86]	-7	hSpCas9	negative selection	1873602
18852246	18852269	19	-	26627737	HCT116	viability after 8 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-3.001659791924465	[339]	[24,4,39]	-9	hSpCas9	negative selection	1873603
18832197	18832220	19	+	26627737	HCT116	viability after 9 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-3.863290840151691	[3035]	[110,11]	-9	hSpCas9	negative selection	1955913
18846039	18846062	19	-	26627737	HCT116	viability after 9 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	0.8926260552254034	[605]	[181,393]	6	hSpCas9	negative selection	1955914
18847767	18847790	19	-	26627737	HCT116	viability after 9 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-4.771244628648323	[327]	[5,0]	-9	hSpCas9	negative selection	1955915
18850108	18850131	19	+	26627737	HCT116	viability after 9 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-0.1022737198279613	[469]	[174,70]	0	hSpCas9	negative selection	1955916
18850772	18850795	19	-	26627737	HCT116	viability after 9 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-4.07300126954457	[1041]	[20,12]	-9	hSpCas9	negative selection	1955917
18852246	18852269	19	-	26627737	HCT116	viability after 9 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-5.217695676757826	[569]	[7,0]	-9	hSpCas9	negative selection	1955918
18832197	18832220	19	+	26627737	HCT116	viability after 12 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-3.3013706638095415	[1386]	[8,93,124]	-9	hSpCas9	negative selection	2038228
18846039	18846062	19	-	26627737	HCT116	viability after 12 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.15822719343941993	[364]	[95,198,227]	-2	hSpCas9	negative selection	2038229
18847767	18847790	19	-	26627737	HCT116	viability after 12 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-1.6736309214928315	[67]	[4,4,23]	-9	hSpCas9	negative selection	2038230
18850108	18850131	19	+	26627737	HCT116	viability after 12 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-0.8491214860046745	[359]	[132,120,58]	-7	hSpCas9	negative selection	2038231
18850772	18850795	19	-	26627737	HCT116	viability after 12 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-1.2450065959133427	[260]	[43,64,65]	-8	hSpCas9	negative selection	2038232
18852246	18852269	19	-	26627737	HCT116	viability after 12 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-3.9438781677899146	[339]	[1,24,8]	-9	hSpCas9	negative selection	2038233
18832197	18832220	19	+	26627737	HCT116	viability after 15 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-3.264121323526775	[1386]	[79,53,113]	-9	hSpCas9	negative selection	2120543
18846039	18846062	19	-	26627737	HCT116	viability after 15 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.0704396604953059	[364]	[200,193,203]	0	hSpCas9	negative selection	2120544
18847767	18847790	19	-	26627737	HCT116	viability after 15 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-3.370147209905947	[67]	[8,1,0]	-9	hSpCas9	negative selection	2120545
18850108	18850131	19	+	26627737	HCT116	viability after 15 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-0.9013095622626361	[359]	[204,64,73]	-7	hSpCas9	negative selection	2120546
18850772	18850795	19	-	26627737	HCT116	viability after 15 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-1.3721277194362034	[260]	[44,56,69]	-8	hSpCas9	negative selection	2120547
18852246	18852269	19	-	26627737	HCT116	viability after 15 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-4.129608172746853	[339]	[0,0,29]	-9	hSpCas9	negative selection	2120548
18832197	18832220	19	+	26627737	HCT116	viability after 18 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-3.190868925241101	[1386]	[16,81,122]	-9	hSpCas9	negative selection	2202858
18846039	18846062	19	-	26627737	HCT116	viability after 18 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.2522207209641051	[364]	[175,174,88]	-2	hSpCas9	negative selection	2202859
18847767	18847790	19	-	26627737	HCT116	viability after 18 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-5.038910465594918	[67]	[0,0,0]	-9	hSpCas9	negative selection	2202860
18850108	18850131	19	+	26627737	HCT116	viability after 18 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-1.126678150292218	[359]	[140,46,51]	-7	hSpCas9	negative selection	2202861
18850772	18850795	19	-	26627737	HCT116	viability after 18 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-1.3777761145679521	[260]	[26,45,73]	-8	hSpCas9	negative selection	2202862
18852246	18852269	19	-	26627737	HCT116	viability after 18 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-4.745063512735808	[339]	[0,2,14]	-9	hSpCas9	negative selection	2202863
18832197	18832220	19	+	24336569	HL60	viability	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-2.263361743737285	[725]	[319]	-9	hSpCas9	negative selection	2305177
18832207	18832230	19	+	24336569	HL60	viability	ACCATGAGCGTGGAGGCGTACGG	UPF1	ENSG00000005007	-1.379432296572077	[1044]	[849]	-8	hSpCas9	negative selection	2305178
18832231	18832254	19	-	24336569	HL60	viability	AAAGTGAGAGTCTGCGAGCTGGG	UPF1	ENSG00000005007	0.6751048982659598	[920]	[3111]	6	hSpCas9	negative selection	2305179
18832236	18832259	19	+	24336569	HL60	viability	CTCGCAGACTCTCACTTTCCTGG	UPF1	ENSG00000005007	-0.26335147401984427	[438]	[773]	-2	hSpCas9	negative selection	2305180
18832242	18832265	19	+	24336569	HL60	viability	GACTCTCACTTTCCTGGACACGG	UPF1	ENSG00000005007	0.3278370291008031	[566]	[1505]	3	hSpCas9	negative selection	2305181
18832248	18832271	19	+	24336569	HL60	viability	CACTTTCCTGGACACGGAGGAGG	UPF1	ENSG00000005007	2.145044429179783	[99]	[935]	9	hSpCas9	negative selection	2305182
18832254	18832277	19	-	24336569	HL60	viability	GCTCGGCCTCCTCCGTGTCCAGG	UPF1	ENSG00000005007	0.3924670877035161	[809]	[2249]	3	hSpCas9	negative selection	2305183
18832261	18832284	19	+	24336569	HL60	viability	ACGGAGGAGGCCGAGCTGCTTGG	UPF1	ENSG00000005007	0.21782619057873448	[333]	[821]	2	hSpCas9	negative selection	2305184
18832271	18832294	19	-	24336569	HL60	viability	TGTGTCGGCGCCAAGCAGCTCGG	UPF1	ENSG00000005007	-2.0814641006288968	[1]	[0]	-9	hSpCas9	negative selection	2305185
18832276	18832299	19	+	24336569	HL60	viability	CTGCTTGGCGCCGACACACAGGG	UPF1	ENSG00000005007	-0.0760302145782682	[264]	[531]	0	hSpCas9	negative selection	2305186
18832197	18832220	19	+	24336569	KBM7	viability	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-2.0475278771938847	[628]	[414]	-8	hSpCas9	negative selection	2372354
18832207	18832230	19	+	24336569	KBM7	viability	ACCATGAGCGTGGAGGCGTACGG	UPF1	ENSG00000005007	-1.5150071240691732	[875]	[835]	-7	hSpCas9	negative selection	2372355
18832231	18832254	19	-	24336569	KBM7	viability	AAAGTGAGAGTCTGCGAGCTGGG	UPF1	ENSG00000005007	-0.24856603553836773	[550]	[1264]	-2	hSpCas9	negative selection	2372356
18832236	18832259	19	+	24336569	KBM7	viability	CTCGCAGACTCTCACTTTCCTGG	UPF1	ENSG00000005007	0.2750469583448036	[272]	[900]	2	hSpCas9	negative selection	2372357
18832242	18832265	19	+	24336569	KBM7	viability	GACTCTCACTTTCCTGGACACGG	UPF1	ENSG00000005007	-1.19272942341577	[382]	[456]	-7	hSpCas9	negative selection	2372358
18832248	18832271	19	+	24336569	KBM7	viability	CACTTTCCTGGACACGGAGGAGG	UPF1	ENSG00000005007	-1.1105442092713116	[208]	[263]	-7	hSpCas9	negative selection	2372359
18832254	18832277	19	-	24336569	KBM7	viability	GCTCGGCCTCCTCCGTGTCCAGG	UPF1	ENSG00000005007	-0.4179017901372174	[841]	[1718]	-3	hSpCas9	negative selection	2372360
18832261	18832284	19	+	24336569	KBM7	viability	ACGGAGGAGGCCGAGCTGCTTGG	UPF1	ENSG00000005007	-0.7093202853611559	[222]	[371]	-5	hSpCas9	negative selection	2372361
18832271	18832294	19	-	24336569	KBM7	viability	TGTGTCGGCGCCAAGCAGCTCGG	UPF1	ENSG00000005007	0.6831244950957109	[28]	[126]	6	hSpCas9	negative selection	2372362
18832276	18832299	19	+	24336569	KBM7	viability	CTGCTTGGCGCCGACACACAGGG	UPF1	ENSG00000005007	1.1301607857540352	[266]	[1593]	8	hSpCas9	negative selection	2372363
18837010	18837033	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGGCTGTAATCCCAGCACTTTAG	UPF1	ENSG00000005007	-1.4185181893877035	[80,53]	[4,4]	-7	dCas9-VP64	positive selection	2423355
18837010	18837033	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGGCTGTAATCCCAGCACTTTAG	UPF1	ENSG00000005007	-0.5867812044469465	[72,239]	[21,43]	-6	dCas9-VP64	positive selection	2518610
18854671	18854694	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTTCCACACAAAATCCACCTGG	UPF1	ENSG00000005007	-0.8252053441610098	[3,3]	[1,0]	-8	hSpCas9	positive selection	3031052
18856042	18856065	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGGGCCAGAAAAGACACCGGG	UPF1	ENSG00000005007	-1.39846745395417	[2,2]	[0,0]	-9	hSpCas9	positive selection	3031053
18854657	18854680	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-0.6328199655508489	[2,3]	[1,0]	-7	hSpCas9	positive selection	3031054
18854917	18854940	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-0.9270372912936665	[2,1]	[0,0]	-9	hSpCas9	positive selection	3031055
18854671	18854694	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTTCCACACAAAATCCACCTGG	UPF1	ENSG00000005007	-0.0961760577191679	[3,3]	[3,1]	-1	hSpCas9	positive selection	3098910
18856042	18856065	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGGGCCAGAAAAGACACCGGG	UPF1	ENSG00000005007	-0.043199925310152154	[2,2]	[3,0]	0	hSpCas9	positive selection	3098911
18854657	18854680	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-0.48054171308435206	[2,2]	[2,0]	-7	hSpCas9	positive selection	3098912
18854917	18854940	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-0.016847345725400142	[2,2]	[0,1]	0	hSpCas9	positive selection	3098913
18852230	18852253		-	24336571	A375	resistance to PLX after 7 days	CCAGGGGCCCGAATATGTTCTGG	UPF1	ENSG00000005007	0.12398290222389652	[8,8]	[8,9]	4	hSpCas9	positive selection	3154406
18852266	18852289		+	24336571	A375	resistance to PLX after 7 days	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	0.5015616177109696	[4,3]	[5,6]	9	hSpCas9	positive selection	3154407
18854888	18854911		+	24336571	A375	resistance to PLX after 7 days	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	0.396573643832026	[6,6]	[10,6]	8	hSpCas9	positive selection	3154408
18854954	18854977		-	24336571	A375	resistance to PLX after 7 days	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	0.15708024605350085	[14,17]	[15,19]	5	hSpCas9	positive selection	3154409
18852230	18852253		-	24336571	A375	resistance to PLX after 14 days	CCAGGGGCCCGAATATGTTCTGG	UPF1	ENSG00000005007	0.1641317032178563	[10,9]	[4,5]	1	hSpCas9	positive selection	3212199
18852266	18852289		+	24336571	A375	resistance to PLX after 14 days	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	0.4684896715565111	[4,4]	[2,2]	4	hSpCas9	positive selection	3212200
18854888	18854911		+	24336571	A375	resistance to PLX after 14 days	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	1.2382923904370202	[8,8]	[9,9]	8	hSpCas9	positive selection	3212201
18854954	18854977		-	24336571	A375	resistance to PLX after 14 days	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	0.16014818675925385	[11,23]	[11,6]	1	hSpCas9	positive selection	3212202
18852230	18852253		-	24336571	A375	viability after 7 days	CCAGGGGCCCGAATATGTTCTGG	UPF1	ENSG00000005007	-0.10231118716163096	[9]	[8,8]	-1	hSpCas9	negative selection	3269992
18852266	18852289		+	24336571	A375	viability after 7 days	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.8843736555853192	[9]	[4,3]	-8	hSpCas9	negative selection	3269993
18854888	18854911		+	24336571	A375	viability after 7 days	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.7778507705356302	[12]	[6,6]	-8	hSpCas9	negative selection	3269994
18854954	18854977		-	24336571	A375	viability after 7 days	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.3973034740327753	[22]	[14,17]	-5	hSpCas9	negative selection	3269995
18852230	18852253		-	24336571	A375	viability after 14 days	CCAGGGGCCCGAATATGTTCTGG	UPF1	ENSG00000005007	0.17395359067783545	[9]	[10,9]	2	hSpCas9	negative selection	3327785
18852266	18852289		+	24336571	A375	viability after 14 days	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.8468797701816386	[9]	[4,4]	-8	hSpCas9	negative selection	3327786
18854888	18854911		+	24336571	A375	viability after 14 days	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.3763397734897211	[12]	[8,8]	-4	hSpCas9	negative selection	3327787
18854954	18854977		-	24336571	A375	viability after 14 days	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.25393875761820656	[22]	[11,23]	-3	hSpCas9	negative selection	3327788
18856245	18856268	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	1.7027373597681978	[46,46]	[0,0]	7	hSpCas9	positive selection	3400384
18854888	18854911	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.28956824844180157	[186,186]	[0,0]	-2	hSpCas9	positive selection	3400385
18854954	18854977	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	0.7337642553888224	[91,91]	[0,0]	3	hSpCas9	positive selection	3400386
18854671	18854694	19	-	26780180	HT29	viability (Avana library 4 designs)	ACTTCCACACAAAATCCACCTGG	UPF1	ENSG00000005007	3.42829350291284	[]	[]	9	hSpCas9	negative selection	3470007
18856042	18856065	19	-	26780180	HT29	viability (Avana library 4 designs)	GCAGGGCCAGAAAAGACACCGGG	UPF1	ENSG00000005007	3.99018950612283	[]	[]	9	hSpCas9	negative selection	3470008
18854656	18854679	19	+	26780180	HT29	viability (Avana library 4 designs)	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	5.11333302101955	[]	[]	9	hSpCas9	negative selection	3470009
18854917	18854940	19	-	26780180	HT29	viability (Avana library 4 designs)	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	3.86803253318664	[]	[]	9	hSpCas9	negative selection	3470010
18854917	18854940	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-5.33901388580133	[]	[]	-5	hSpCas9	negative selection	3575501
18854656	18854679	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-2.9572548305462	[]	[]	-4	hSpCas9	negative selection	3575502
18854671	18854694	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTTCCACACAAAATCCACCTGG	UPF1	ENSG00000005007	-2.47432359614594	[]	[]	-3	hSpCas9	negative selection	3575503
18856042	18856065	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGGCCAGAAAAGACACCGGG	UPF1	ENSG00000005007	-5.19637099397201	[]	[]	-5	hSpCas9	negative selection	3575504
18850093	18850116	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGAGGGCAAAATGCAAAGAGG	UPF1	ENSG00000005007	-6.52569834601235	[]	[]	-6	hSpCas9	negative selection	3575505
18847779	18847802	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGTAATACCAGCAAGAAGTGG	UPF1	ENSG00000005007	-10.0460612062591	[]	[]	-7	hSpCas9	negative selection	3575506
18854917	18854940	19	-	26780180	A375	viability (Avana lentiGuide)	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	20.028341565051	[]	[]	8	hSpCas9	negative selection	3684160
18854656	18854679	19	+	26780180	A375	viability (Avana lentiGuide)	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	17.6541540270883	[]	[]	8	hSpCas9	negative selection	3684161
18854671	18854694	19	-	26780180	A375	viability (Avana lentiGuide)	ACTTCCACACAAAATCCACCTGG	UPF1	ENSG00000005007	9.58258112160038	[]	[]	6	hSpCas9	negative selection	3684162
18856042	18856065	19	-	26780180	A375	viability (Avana lentiGuide)	GCAGGGCCAGAAAAGACACCGGG	UPF1	ENSG00000005007	7.25479586086174	[]	[]	6	hSpCas9	negative selection	3684163
18850093	18850116	19	+	26780180	A375	viability (Avana lentiGuide)	TGTGAGGGCAAAATGCAAAGAGG	UPF1	ENSG00000005007	32.4705448219736	[]	[]	9	hSpCas9	negative selection	3684164
18847779	18847802	19	+	26780180	A375	viability (Avana lentiGuide)	ACTGTAATACCAGCAAGAAGTGG	UPF1	ENSG00000005007	8.0792504806792	[]	[]	6	hSpCas9	negative selection	3684165
18854917	18854940	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-0.6702157470212917	[4]	[3,1]	-7	hSpCas9	positive selection	3792767
18854656	18854679	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-0.1882815655651911	[4]	[4,2]	-3	hSpCas9	positive selection	3792768
18854671	18854694	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTTCCACACAAAATCCACCTGG	UPF1	ENSG00000005007	-0.0839315665161275	[4]	[4,4]	-1	hSpCas9	positive selection	3792769
18856042	18856065	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGGCCAGAAAAGACACCGGG	UPF1	ENSG00000005007	-0.3485198782748176	[3]	[3,1]	-5	hSpCas9	positive selection	3792770
18850093	18850116	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGAGGGCAAAATGCAAAGAGG	UPF1	ENSG00000005007	-1.0864538313321206	[4]	[2,1]	-9	hSpCas9	positive selection	3792771
18847779	18847802	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGTAATACCAGCAAGAAGTGG	UPF1	ENSG00000005007	-0.7806475178883177	[6]	[2,3]	-8	hSpCas9	positive selection	3792772
18854917	18854940	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-0.9460664520220028	[4]	[0,2]	-8	hSpCas9	positive selection	3901374
18854656	18854679	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-0.8810187571317198	[5]	[1,2]	-8	hSpCas9	positive selection	3901375
18854671	18854694	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTTCCACACAAAATCCACCTGG	UPF1	ENSG00000005007	-0.14412819612354527	[6]	[5,3]	-2	hSpCas9	positive selection	3901376
18856042	18856065	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGGCCAGAAAAGACACCGGG	UPF1	ENSG00000005007	-0.5101051338038319	[5]	[2,2]	-6	hSpCas9	positive selection	3901377
18850093	18850116	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGAGGGCAAAATGCAAAGAGG	UPF1	ENSG00000005007	-1.9492579181359493	[5]	[0,0]	-9	hSpCas9	positive selection	3901378
18847779	18847802	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGTAATACCAGCAAGAAGTGG	UPF1	ENSG00000005007	-0.4582514553695163	[6]	[3,3]	-5	hSpCas9	positive selection	3901379
18852266	18852289	19	+	26780180	A375	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	1.94756416826192	[]	[]	9	hSpCas9	negative selection	4010498
18854888	18854911	19	+	26780180	A375	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	1.75192267444175	[]	[]	9	hSpCas9	negative selection	4010499
18856245	18856268	19	-	26780180	A375	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	1.65978351574808	[]	[]	8	hSpCas9	negative selection	4010500
18852203	18852226	19	-	26780180	A375	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	1.99659438495392	[]	[]	9	hSpCas9	negative selection	4010501
18854954	18854977	19	-	26780180	A375	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	2.46735545625467	[]	[]	9	hSpCas9	negative selection	4010502
18856236	18856259	19	+	26780180	A375	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	1.58088644908774	[]	[]	8	hSpCas9	negative selection	4010503
18852266	18852289	19	+	26780180	HT29	viability (GeCKOv2 library)	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	2.16381450844525	[]	[]	9	hSpCas9	negative selection	4118464
18854888	18854911	19	+	26780180	HT29	viability (GeCKOv2 library)	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	2.16398233237001	[]	[]	9	hSpCas9	negative selection	4118465
18856245	18856268	19	-	26780180	HT29	viability (GeCKOv2 library)	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	2.32820204775444	[]	[]	9	hSpCas9	negative selection	4118466
18852203	18852226	19	-	26780180	HT29	viability (GeCKOv2 library)	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	2.64780465203439	[]	[]	9	hSpCas9	negative selection	4118467
18854954	18854977	19	-	26780180	HT29	viability (GeCKOv2 library)	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	2.69186332141957	[]	[]	9	hSpCas9	negative selection	4118468
18856236	18856259	19	+	26780180	HT29	viability (GeCKOv2 library)	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.896610578102595	[]	[]	4	hSpCas9	negative selection	4118469
18852230	18852253	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGGGGCCCGAATATGTTCTGG	UPF1	ENSG00000005007	0.22811539031327974	[2]	[2,2]	6	hSpCas9	positive selection	4181108
18852266	18852289	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.6495612098538177	[2]	[0,1]	-9	hSpCas9	positive selection	4181109
18854888	18854911	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	0.1814149042760852	[3]	[1,3]	4	hSpCas9	positive selection	4181110
18854954	18854977	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.04166571197245392	[4]	[2,3]	-1	hSpCas9	positive selection	4181111
18852230	18852253	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGGGGCCCGAATATGTTCTGG	UPF1	ENSG00000005007	-0.38744628951522014	[2]	[0,0,0,0]	-5	hSpCas9	positive selection	4245130
18852266	18852289	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.7128938377519229	[2]	[0,0,0,0]	-8	hSpCas9	positive selection	4245131
18854888	18854911	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	0.9647876368386827	[1]	[0,2,5,0]	6	hSpCas9	positive selection	4245132
18854954	18854977	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.34039049070102595	[3]	[0,0,3,0]	-5	hSpCas9	positive selection	4245133
18852203	18852226	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.4206275420556146	[2]	[2,0]	-7	hSpCas9	positive selection	4306674
18852266	18852289	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.4136467520962054	[2]	[2,0]	-7	hSpCas9	positive selection	4306675
18856236	18856259	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.4647033923660958	[2]	[2,2]	8	hSpCas9	positive selection	4306676
18856245	18856268	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.8251840546201366	[2]	[0,0]	-9	hSpCas9	positive selection	4370922
18854888	18854911	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.42677521953274855	[3]	[2,1]	-7	hSpCas9	positive selection	4370923
18854954	18854977	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.28896673622112934	[3]	[2,1]	-5	hSpCas9	positive selection	4370924
18855227	18855249	19	+	27760321	OCIAML3	viability	CCCGGCAAGGCAACGGGTAGGG	UPF1	ENSG00000005007	-1.8878355709531056	[510,410]	[72,127]	-9	hSpCas9	negative selection	4452413
18855953	18855975	19	+	27760321	OCIAML3	viability	ATCGCCGTGGACCAGCTAACGG	UPF1	ENSG00000005007	-1.5296019126114424	[539,468]	[121,154]	-8	hSpCas9	negative selection	4452414
18847797	18847819	19	+	27760321	OCIAML3	viability	AGTGGTTCTGCAACGGACGTGG	UPF1	ENSG00000005007	-0.32083375494416666	[519,427]	[274,321]	-3	hSpCas9	negative selection	4452415
18850812	18850834	19	+	27760321	OCIAML3	viability	CTGCGGGCACGCCAGATCACGG	UPF1	ENSG00000005007	-0.12265075315459928	[669,483]	[336,505]	-1	hSpCas9	negative selection	4452416
18852200	18852222	19	-	27760321	OCIAML3	viability	GGCGTCCTCGTACCGCAGGAGG	UPF1	ENSG00000005007	-1.5483383018981978	[628,536]	[157,151]	-8	hSpCas9	negative selection	4452417
18855227	18855249	19	+	27760321	OCIAML2	viability	CCCGGCAAGGCAACGGGTAGGG	UPF1	ENSG00000005007	-0.6618713051038623	[510,410]	[239,226]	-6	hSpCas9	negative selection	4535876
18855953	18855975	19	+	27760321	OCIAML2	viability	ATCGCCGTGGACCAGCTAACGG	UPF1	ENSG00000005007	-1.8645223557006683	[539,468]	[78,154]	-9	hSpCas9	negative selection	4535877
18847797	18847819	19	+	27760321	OCIAML2	viability	AGTGGTTCTGCAACGGACGTGG	UPF1	ENSG00000005007	-1.2520959553228206	[519,427]	[167,149]	-8	hSpCas9	negative selection	4535878
18850812	18850834	19	+	27760321	OCIAML2	viability	CTGCGGGCACGCCAGATCACGG	UPF1	ENSG00000005007	-0.6977951462689724	[669,483]	[214,376]	-6	hSpCas9	negative selection	4535879
18852200	18852222	19	-	27760321	OCIAML2	viability	GGCGTCCTCGTACCGCAGGAGG	UPF1	ENSG00000005007	-1.6414157227553132	[628,536]	[132,173]	-8	hSpCas9	negative selection	4535880
18855227	18855249	19	+	27760321	MV411	viability	CCCGGCAAGGCAACGGGTAGGG	UPF1	ENSG00000005007	-1.3417610822436297	[510,410]	[58,209]	-7	hSpCas9	negative selection	4619339
18855953	18855975	19	+	27760321	MV411	viability	ATCGCCGTGGACCAGCTAACGG	UPF1	ENSG00000005007	-1.2316616810071246	[539,468]	[156,117]	-7	hSpCas9	negative selection	4619340
18847797	18847819	19	+	27760321	MV411	viability	AGTGGTTCTGCAACGGACGTGG	UPF1	ENSG00000005007	-1.6162155611521174	[519,427]	[43,187]	-8	hSpCas9	negative selection	4619341
18850812	18850834	19	+	27760321	MV411	viability	CTGCGGGCACGCCAGATCACGG	UPF1	ENSG00000005007	-0.9515122400748144	[669,483]	[110,320]	-6	hSpCas9	negative selection	4619342
18852200	18852222	19	-	27760321	MV411	viability	GGCGTCCTCGTACCGCAGGAGG	UPF1	ENSG00000005007	-0.20441453013508193	[628,536]	[128,638]	-1	hSpCas9	negative selection	4619343
18855227	18855249	19	+	27760321	HL60	viability	CCCGGCAAGGCAACGGGTAGGG	UPF1	ENSG00000005007	-1.4221209128543386	[510,410]	[130,148]	-8	hSpCas9	negative selection	4702802
18855953	18855975	19	+	27760321	HL60	viability	ATCGCCGTGGACCAGCTAACGG	UPF1	ENSG00000005007	-0.38829694442437124	[539,468]	[349,275]	-4	hSpCas9	negative selection	4702803
18847797	18847819	19	+	27760321	HL60	viability	AGTGGTTCTGCAACGGACGTGG	UPF1	ENSG00000005007	0.7609970641357878	[519,427]	[672,631]	8	hSpCas9	negative selection	4702804
18850812	18850834	19	+	27760321	HL60	viability	CTGCGGGCACGCCAGATCACGG	UPF1	ENSG00000005007	-0.933111654017359	[669,483]	[240,247]	-7	hSpCas9	negative selection	4702805
18852200	18852222	19	-	27760321	HL60	viability	GGCGTCCTCGTACCGCAGGAGG	UPF1	ENSG00000005007	-1.8152327106224264	[628,536]	[147,120]	-9	hSpCas9	negative selection	4702806
18855227	18855249	19	+	27760321	HT1080	viability	CCCGGCAAGGCAACGGGTAGGG	UPF1	ENSG00000005007	-2.2105869348033393	[410,320]	[20,42]	-6	hSpCas9	negative selection	4786265
18855953	18855975	19	+	27760321	HT1080	viability	ATCGCCGTGGACCAGCTAACGG	UPF1	ENSG00000005007	-1.2820875795966362	[468,365]	[44,93]	-5	hSpCas9	negative selection	4786266
18847797	18847819	19	+	27760321	HT1080	viability	AGTGGTTCTGCAACGGACGTGG	UPF1	ENSG00000005007	-4.1351842396262315	[427,333]	[0,16]	-8	hSpCas9	negative selection	4786267
18850812	18850834	19	+	27760321	HT1080	viability	CTGCGGGCACGCCAGATCACGG	UPF1	ENSG00000005007	-7.423787418835892	[483,377]	[0,0]	-9	hSpCas9	negative selection	4786268
18852200	18852222	19	-	27760321	HT1080	viability	GGCGTCCTCGTACCGCAGGAGG	UPF1	ENSG00000005007	-1.086321139702548	[536,418]	[103,73]	-4	hSpCas9	negative selection	4786269
18855227	18855249	19	+	27760321	HT29	viability after 7 days	CCCGGCAAGGCAACGGGTAGGG	UPF1	ENSG00000005007	-0.4739641063840637	[410,320]	[372,345,302]	-6	hSpCas9	negative selection	4869728
18855953	18855975	19	+	27760321	HT29	viability after 7 days	ATCGCCGTGGACCAGCTAACGG	UPF1	ENSG00000005007	-1.1223725112739484	[468,365]	[273,341,130]	-8	hSpCas9	negative selection	4869729
18847797	18847819	19	+	27760321	HT29	viability after 7 days	AGTGGTTCTGCAACGGACGTGG	UPF1	ENSG00000005007	-0.3061187008549878	[427,333]	[398,188,593]	-4	hSpCas9	negative selection	4869730
18850812	18850834	19	+	27760321	HT29	viability after 7 days	CTGCGGGCACGCCAGATCACGG	UPF1	ENSG00000005007	-0.11714578792927013	[483,377]	[636,685,235]	-2	hSpCas9	negative selection	4869731
18852200	18852222	19	-	27760321	HT29	viability after 7 days	GGCGTCCTCGTACCGCAGGAGG	UPF1	ENSG00000005007	-0.5569325562958309	[536,418]	[399,460,389]	-7	hSpCas9	negative selection	4869732
18855227	18855249	19	+	27760321	HT29	viability after 25 days	CCCGGCAAGGCAACGGGTAGGG	UPF1	ENSG00000005007	-4.430941361145241	[410,320]	[30,1,24]	-9	hSpCas9	negative selection	4953191
18855953	18855975	19	+	27760321	HT29	viability after 25 days	ATCGCCGTGGACCAGCTAACGG	UPF1	ENSG00000005007	-8.515861799937223	[468,365]	[0,0,1]	-9	hSpCas9	negative selection	4953192
18847797	18847819	19	+	27760321	HT29	viability after 25 days	AGTGGTTCTGCAACGGACGTGG	UPF1	ENSG00000005007	-2.3362766864099926	[427,333]	[20,91,156]	-8	hSpCas9	negative selection	4953193
18850812	18850834	19	+	27760321	HT29	viability after 25 days	CTGCGGGCACGCCAGATCACGG	UPF1	ENSG00000005007	-1.5315758411676716	[483,377]	[158,264,77]	-7	hSpCas9	negative selection	4953194
18852200	18852222	19	-	27760321	HT29	viability after 25 days	GGCGTCCTCGTACCGCAGGAGG	UPF1	ENSG00000005007	-1.6850530360498535	[536,418]	[71,243,202]	-7	hSpCas9	negative selection	4953195
18855227	18855249	19	+	27760321	HT29	viability after 22 days	CCCGGCAAGGCAACGGGTAGGG	UPF1	ENSG00000005007	-4.845365594072067	[410,320]	[21,2,18]	-9	hSpCas9	negative selection	5036654
18855953	18855975	19	+	27760321	HT29	viability after 22 days	ATCGCCGTGGACCAGCTAACGG	UPF1	ENSG00000005007	-7.156734099759165	[468,365]	[7,0,0]	-9	hSpCas9	negative selection	5036655
18847797	18847819	19	+	27760321	HT29	viability after 22 days	AGTGGTTCTGCAACGGACGTGG	UPF1	ENSG00000005007	-2.868394892022934	[427,333]	[42,120,16]	-8	hSpCas9	negative selection	5036656
18850812	18850834	19	+	27760321	HT29	viability after 22 days	CTGCGGGCACGCCAGATCACGG	UPF1	ENSG00000005007	-1.4274058565279475	[483,377]	[216,247,88]	-7	hSpCas9	negative selection	5036657
18852200	18852222	19	-	27760321	HT29	viability after 22 days	GGCGTCCTCGTACCGCAGGAGG	UPF1	ENSG00000005007	-2.2083598650775986	[536,418]	[153,59,143]	-8	hSpCas9	negative selection	5036658
18855227	18855249	19	+	27760321	HT29	viability after 19 days	CCCGGCAAGGCAACGGGTAGGG	UPF1	ENSG00000005007	-3.823773577973881	[410,320]	[0,36,46]	-9	hSpCas9	negative selection	5120117
18855953	18855975	19	+	27760321	HT29	viability after 19 days	ATCGCCGTGGACCAGCTAACGG	UPF1	ENSG00000005007	-7.278236747908276	[468,365]	[1,0,5]	-9	hSpCas9	negative selection	5120118
18847797	18847819	19	+	27760321	HT29	viability after 19 days	AGTGGTTCTGCAACGGACGTGG	UPF1	ENSG00000005007	-3.2833358207235612	[427,333]	[83,53,1]	-9	hSpCas9	negative selection	5120119
18850812	18850834	19	+	27760321	HT29	viability after 19 days	CTGCGGGCACGCCAGATCACGG	UPF1	ENSG00000005007	-1.2615159227036656	[483,377]	[248,213,159]	-7	hSpCas9	negative selection	5120120
18852200	18852222	19	-	27760321	HT29	viability after 19 days	GGCGTCCTCGTACCGCAGGAGG	UPF1	ENSG00000005007	-2.203724868167795	[536,418]	[48,163,134]	-8	hSpCas9	negative selection	5120121
18855227	18855249	19	+	27760321	HT29	viability after 16 days	CCCGGCAAGGCAACGGGTAGGG	UPF1	ENSG00000005007	-3.755261919882825	[410,320]	[75,2,16]	-9	hSpCas9	negative selection	5203580
18855953	18855975	19	+	27760321	HT29	viability after 16 days	ATCGCCGTGGACCAGCTAACGG	UPF1	ENSG00000005007	-3.408965755730766	[468,365]	[19,68,39]	-9	hSpCas9	negative selection	5203581
18847797	18847819	19	+	27760321	HT29	viability after 16 days	AGTGGTTCTGCAACGGACGTGG	UPF1	ENSG00000005007	-2.4290823218727637	[427,333]	[49,66,117]	-8	hSpCas9	negative selection	5203582
18850812	18850834	19	+	27760321	HT29	viability after 16 days	CTGCGGGCACGCCAGATCACGG	UPF1	ENSG00000005007	-0.6747701365366857	[483,377]	[380,326,204]	-6	hSpCas9	negative selection	5203583
18852200	18852222	19	-	27760321	HT29	viability after 16 days	GGCGTCCTCGTACCGCAGGAGG	UPF1	ENSG00000005007	-2.5090750969021007	[536,418]	[103,84,93]	-8	hSpCas9	negative selection	5203584
18855227	18855249	19	+	27760321	HT29	viability after 13 days	CCCGGCAAGGCAACGGGTAGGG	UPF1	ENSG00000005007	-4.010401748266817	[410,320]	[50,18,9]	-9	hSpCas9	negative selection	5287043
18855953	18855975	19	+	27760321	HT29	viability after 13 days	ATCGCCGTGGACCAGCTAACGG	UPF1	ENSG00000005007	-4.3408386782599715	[468,365]	[52,0,17]	-9	hSpCas9	negative selection	5287044
18847797	18847819	19	+	27760321	HT29	viability after 13 days	AGTGGTTCTGCAACGGACGTGG	UPF1	ENSG00000005007	-3.527024532498737	[427,333]	[4,35,71]	-9	hSpCas9	negative selection	5287045
18850812	18850834	19	+	27760321	HT29	viability after 13 days	CTGCGGGCACGCCAGATCACGG	UPF1	ENSG00000005007	-0.6340271986617283	[483,377]	[446,345,181]	-6	hSpCas9	negative selection	5287046
18852200	18852222	19	-	27760321	HT29	viability after 13 days	GGCGTCCTCGTACCGCAGGAGG	UPF1	ENSG00000005007	-2.1045311854250555	[536,418]	[149,77,156]	-8	hSpCas9	negative selection	5287047
18855227	18855249	19	+	27760321	HT29	viability after 10 days	CCCGGCAAGGCAACGGGTAGGG	UPF1	ENSG00000005007	-2.1965348994568825	[410,320]	[77,167,55]	-9	hSpCas9	negative selection	5370506
18855953	18855975	19	+	27760321	HT29	viability after 10 days	ATCGCCGTGGACCAGCTAACGG	UPF1	ENSG00000005007	-3.5295263005869657	[468,365]	[8,52,72]	-9	hSpCas9	negative selection	5370507
18847797	18847819	19	+	27760321	HT29	viability after 10 days	AGTGGTTCTGCAACGGACGTGG	UPF1	ENSG00000005007	-1.5405918966875942	[427,333]	[174,227,90]	-8	hSpCas9	negative selection	5370508
18850812	18850834	19	+	27760321	HT29	viability after 10 days	CTGCGGGCACGCCAGATCACGG	UPF1	ENSG00000005007	-0.9910315458760752	[483,377]	[302,231,275]	-8	hSpCas9	negative selection	5370509
18852200	18852222	19	-	27760321	HT29	viability after 10 days	GGCGTCCTCGTACCGCAGGAGG	UPF1	ENSG00000005007	-1.8413091850511756	[536,418]	[155,198,145]	-9	hSpCas9	negative selection	5370510
18855227	18855249	19	+	27760321	MOLM13	viability	CCCGGCAAGGCAACGGGTAGGG	UPF1	ENSG00000005007	-1.6146673291351383	[510,410]	[37,123]	-7	hSpCas9	negative selection	5453969
18855953	18855975	19	+	27760321	MOLM13	viability	ATCGCCGTGGACCAGCTAACGG	UPF1	ENSG00000005007	-0.9064115238305375	[539,468]	[292,30]	-5	hSpCas9	negative selection	5453970
18847797	18847819	19	+	27760321	MOLM13	viability	AGTGGTTCTGCAACGGACGTGG	UPF1	ENSG00000005007	-1.430601483544961	[519,427]	[81,112]	-7	hSpCas9	negative selection	5453971
18850812	18850834	19	+	27760321	MOLM13	viability	CTGCGGGCACGCCAGATCACGG	UPF1	ENSG00000005007	-1.76586472754954	[669,483]	[117,74]	-7	hSpCas9	negative selection	5453972
18852200	18852222	19	-	27760321	MOLM13	viability	GGCGTCCTCGTACCGCAGGAGG	UPF1	ENSG00000005007	-1.7377185130347492	[628,536]	[194,15]	-7	hSpCas9	negative selection	5453973
18832183	18832206	19	+	27661255	K562	viability	GGCCCGAGGGCCCTACCCGGAGG	UPF1	ENSG00000005007	-0.35968254160352076	[211,367]	[228,135]	-7	dCas9-KRAB	negative selection	5521595
18852203	18852226	19	-	27260156	BXPC3	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.8617957567433955	[348]	[210,211,187,186]	-9	hSpCas9	negative selection	5579134
18852266	18852289	19	+	27260156	BXPC3	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.11761048787541492	[409]	[263,448,493,381]	-3	hSpCas9	negative selection	5579135
18856236	18856259	19	+	27260156	BXPC3	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.05665253818816862	[297]	[225,372,352,353]	1	hSpCas9	negative selection	5579136
18856245	18856268	19	-	27260156	BXPC3	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.8740519281866388	[362]	[130,156,334,218]	-9	hSpCas9	negative selection	5643382
18854888	18854911	19	+	27260156	BXPC3	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.9285732074640809	[944]	[560,416,563,534]	-9	hSpCas9	negative selection	5643383
18854954	18854977	19	-	27260156	BXPC3	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.8587378985466694	[665]	[400,336,409,386]	-9	hSpCas9	negative selection	5643384
18852203	18852226	19	-	27260156	A673	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.34363184558758797	[348]	[381,274,363,304]	-7	hSpCas9	negative selection	5700385
18852266	18852289	19	+	27260156	A673	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.4183925296828639	[409]	[413,324,343,397]	-8	hSpCas9	negative selection	5700386
18856236	18856259	19	+	27260156	A673	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.04837939050821849	[297]	[386,308,347,344]	-1	hSpCas9	negative selection	5700387
18856245	18856268	19	-	27260156	A673	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.5588065319847035	[362]	[340,249,277,321]	-8	hSpCas9	negative selection	5764633
18854888	18854911	19	+	27260156	A673	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.7245720906373623	[944]	[783,722,588,658]	-9	hSpCas9	negative selection	5764634
18854954	18854977	19	-	27260156	A673	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.6851729582320532	[665]	[621,379,473,531]	-9	hSpCas9	negative selection	5764635
18852203	18852226	19	-	27260156	A375	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.9108674759801548	[348]	[148,269,234,218]	-8	hSpCas9	negative selection	5821636
18852266	18852289	19	+	27260156	A375	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-2.509533556456764	[409]	[96,105,77,60]	-9	hSpCas9	negative selection	5821637
18856236	18856259	19	+	27260156	A375	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.8725826397773392	[297]	[255,359,99,80]	-8	hSpCas9	negative selection	5821638
18856245	18856268	19	-	27260156	A375	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-1.5926993236270277	[362]	[79,121,264,96]	-9	hSpCas9	negative selection	5885884
18854888	18854911	19	+	27260156	A375	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.580497080003461	[944]	[445,358,207,450]	-9	hSpCas9	negative selection	5885885
18854954	18854977	19	-	27260156	A375	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.895161247153933	[665]	[553,188,335,545]	-8	hSpCas9	negative selection	5885886
18852203	18852226	19	-	27260156	COLO741	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.2675019633712551	[348]	[355,447,309]	-5	hSpCas9	negative selection	5942887
18852266	18852289	19	+	27260156	COLO741	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.7253208795171624	[409]	[466,243,255]	-9	hSpCas9	negative selection	5942888
18856236	18856259	19	+	27260156	COLO741	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.10393205059593669	[297]	[566,336,340]	2	hSpCas9	negative selection	5942889
18856245	18856268	19	-	27260156	COLO741	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.9795051166312831	[362]	[246,291,171]	-9	hSpCas9	negative selection	6007135
18854888	18854911	19	+	27260156	COLO741	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.88431004415482	[944]	[693,682,591]	-9	hSpCas9	negative selection	6007136
18854954	18854977	19	-	27260156	COLO741	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.768800926372206	[665]	[563,445,492]	-9	hSpCas9	negative selection	6007137
18852203	18852226	19	-	27260156	CAL120	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.04054883147452032	[348]	[818,236,272]	0	hSpCas9	negative selection	6064138
18852266	18852289	19	+	27260156	CAL120	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.4758647930575288	[409]	[358,416,323]	-6	hSpCas9	negative selection	6064139
18856236	18856259	19	+	27260156	CAL120	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.032370952901310535	[297]	[266,372,431]	0	hSpCas9	negative selection	6064140
18856245	18856268	19	-	27260156	CAL120	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-1.1538289921372535	[362]	[262,152,201]	-9	hSpCas9	negative selection	6128386
18854888	18854911	19	+	27260156	CAL120	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.7079794880416153	[944]	[698,780,676]	-7	hSpCas9	negative selection	6128387
18854954	18854977	19	-	27260156	CAL120	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.7708555251426963	[665]	[483,504,467]	-8	hSpCas9	negative selection	6128388
18852203	18852226	19	-	27260156	CADOES1	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.7222407092317132	[348]	[201,284,133,164]	-8	hSpCas9	negative selection	6185389
18852266	18852289	19	+	27260156	CADOES1	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.5540785703028865	[409]	[263,193,287,293]	-7	hSpCas9	negative selection	6185390
18856236	18856259	19	+	27260156	CADOES1	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.6387816060847558	[297]	[494,511,266,452]	9	hSpCas9	negative selection	6185391
18856245	18856268	19	-	27260156	CADOES1	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.7245300316830452	[362]	[265,165,181,202]	-8	hSpCas9	negative selection	6249637
18854888	18854911	19	+	27260156	CADOES1	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.9741342287430099	[944]	[555,398,494,334]	-9	hSpCas9	negative selection	6249638
18854954	18854977	19	-	27260156	CADOES1	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.9982758584095226	[665]	[368,239,295,335]	-9	hSpCas9	negative selection	6249639
18852203	18852226	19	-	27260156	EWS502	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.5426989742176792	[348]	[284,252,246,222]	-7	hSpCas9	negative selection	6306640
18852266	18852289	19	+	27260156	EWS502	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.8441988565047853	[409]	[144,274,220,342]	-8	hSpCas9	negative selection	6306641
18856236	18856259	19	+	27260156	EWS502	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.46086718029281704	[297]	[425,349,544,419]	7	hSpCas9	negative selection	6306642
18856245	18856268	19	-	27260156	EWS502	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-1.3612874268826407	[362]	[107,177,120,197]	-9	hSpCas9	negative selection	6370888
18854888	18854911	19	+	27260156	EWS502	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.2594444722939229	[944]	[221,326,697,457]	-9	hSpCas9	negative selection	6370889
18854954	18854977	19	-	27260156	EWS502	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.8900703629169533	[665]	[350,376,324,477]	-8	hSpCas9	negative selection	6370890
18852203	18852226	19	-	27260156	EW8	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.6318026089533856	[348]	[176,195,182,172]	-8	hSpCas9	negative selection	6427891
18852266	18852289	19	+	27260156	EW8	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.5222001550867434	[409]	[201,314,177,235]	-7	hSpCas9	negative selection	6427892
18856236	18856259	19	+	27260156	EW8	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.06061343037932099	[297]	[273,255,138,276]	-1	hSpCas9	negative selection	6427893
18856245	18856268	19	-	27260156	EW8	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.8837443421019069	[362]	[106,147,244,116]	-9	hSpCas9	negative selection	6492139
18854888	18854911	19	+	27260156	EW8	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.0735727328886013	[944]	[395,461,356,244]	-9	hSpCas9	negative selection	6492140
18854954	18854977	19	-	27260156	EW8	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.0169420658803876	[665]	[420,249,250,163]	-9	hSpCas9	negative selection	6492141
18852203	18852226	19	-	27260156	CORL105	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.7062471575055368	[348]	[228,273,247,248]	-8	hSpCas9	negative selection	6549142
18852266	18852289	19	+	27260156	CORL105	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.5272905874237287	[409]	[325,241,481,306]	-7	hSpCas9	negative selection	6549143
18856236	18856259	19	+	27260156	CORL105	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.7054362557225212	[297]	[106,264,358,142]	-8	hSpCas9	negative selection	6549144
18856245	18856268	19	-	27260156	CORL105	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-1.2197924294356426	[362]	[174,191,267,107]	-9	hSpCas9	negative selection	6613390
18854888	18854911	19	+	27260156	CORL105	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.7601204486459365	[944]	[495,696,703,716]	-8	hSpCas9	negative selection	6613391
18854954	18854977	19	-	27260156	CORL105	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.1325479889711656	[665]	[457,317,368,283]	-9	hSpCas9	negative selection	6613392
18852203	18852226	19	-	27260156	HS294T	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.7676569455842664	[348]	[66,52,103,97]	-8	hSpCas9	negative selection	6670393
18852266	18852289	19	+	27260156	HS294T	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-1.087025390714415	[409]	[53,49,107,91]	-9	hSpCas9	negative selection	6670394
18856236	18856259	19	+	27260156	HS294T	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.46803538851832915	[297]	[46,41,94,167]	-6	hSpCas9	negative selection	6670395
18856245	18856268	19	-	27260156	HS294T	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-1.398685811059797	[362]	[75,23,30,85]	-9	hSpCas9	negative selection	6734641
18854888	18854911	19	+	27260156	HS294T	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.3463158166049558	[944]	[114,119,158,191]	-9	hSpCas9	negative selection	6734642
18854954	18854977	19	-	27260156	HS294T	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.506856457225239	[665]	[49,109,96,111]	-9	hSpCas9	negative selection	6734643
18852203	18852226	19	-	27260156	HCC44	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.9536730953423623	[348]	[223,222,223,146]	-8	hSpCas9	negative selection	6791644
18852266	18852289	19	+	27260156	HCC44	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-1.9280386581487459	[409]	[151,120,135,83]	-9	hSpCas9	negative selection	6791645
18856236	18856259	19	+	27260156	HCC44	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.19678645208320855	[297]	[466,443,171,419]	3	hSpCas9	negative selection	6791646
18856245	18856268	19	-	27260156	HCC44	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.5979226701272617	[362]	[193,390,256,215]	-7	hSpCas9	negative selection	6855892
18854888	18854911	19	+	27260156	HCC44	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.283891513154388	[944]	[579,321,520,374]	-9	hSpCas9	negative selection	6855893
18854954	18854977	19	-	27260156	HCC44	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.46725437021672	[665]	[235,292,357,210]	-9	hSpCas9	negative selection	6855894
18852203	18852226	19	-	27260156	G402	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-1.158125772094953	[348]	[206,110,97,336]	-8	hSpCas9	negative selection	6912895
18852266	18852289	19	+	27260156	G402	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-1.8258659934371047	[409]	[102,118,148,183]	-9	hSpCas9	negative selection	6912896
18856236	18856259	19	+	27260156	G402	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.14379587444451947	[297]	[310,229,651,123]	-2	hSpCas9	negative selection	6912897
18856245	18856268	19	-	27260156	G402	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.6326999721020043	[362]	[490,129,335,208]	-7	hSpCas9	negative selection	6977143
18854888	18854911	19	+	27260156	G402	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.2559985125218693	[944]	[625,511,442,375]	-8	hSpCas9	negative selection	6977144
18854954	18854977	19	-	27260156	G402	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.356435639315249	[665]	[290,410,209,355]	-9	hSpCas9	negative selection	6977145
18852203	18852226	19	-	27260156	L33	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	0.07649023318217552	[348]	[333,87,321,411]	1	hSpCas9	negative selection	7034146
18852266	18852289	19	+	27260156	L33	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.33419347856385695	[409]	[356,136,218,260]	-7	hSpCas9	negative selection	7034147
18856236	18856259	19	+	27260156	L33	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.3551332769568851	[297]	[474,137,227,347]	7	hSpCas9	negative selection	7034148
18856245	18856268	19	-	27260156	L33	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.9323035426347619	[362]	[130,92,93,253]	-9	hSpCas9	negative selection	7098394
18854888	18854911	19	+	27260156	L33	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.5336541429976436	[944]	[686,214,422,724]	-8	hSpCas9	negative selection	7098395
18854954	18854977	19	-	27260156	L33	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.8349763842857858	[665]	[389,168,229,324]	-9	hSpCas9	negative selection	7098396
18852203	18852226	19	-	27260156	K562	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-1.335503231594374	[348]	[160,155,71,107]	-8	hSpCas9	negative selection	7155397
18852266	18852289	19	+	27260156	K562	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-1.009381027457322	[409]	[225,96,278,125]	-8	hSpCas9	negative selection	7155398
18856236	18856259	19	+	27260156	K562	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.06476451913692116	[297]	[242,348,206,303]	0	hSpCas9	negative selection	7155399
18856245	18856268	19	-	27260156	K562	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-1.2198259789354766	[362]	[184,182,44,144]	-8	hSpCas9	negative selection	7219645
18854888	18854911	19	+	27260156	K562	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.9470670824381141	[944]	[303,455,434,522]	-8	hSpCas9	negative selection	7219646
18854954	18854977	19	-	27260156	K562	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.4766217599021911	[665]	[220,328,107,198]	-9	hSpCas9	negative selection	7219647
18852203	18852226	19	-	27260156	HT29	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-1.4147426675085675	[348]	[209,229,123,89]	-9	hSpCas9	negative selection	7276648
18852266	18852289	19	+	27260156	HT29	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.6094231403945447	[409]	[255,389,220,424]	-7	hSpCas9	negative selection	7276649
18856236	18856259	19	+	27260156	HT29	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.05381371981677563	[297]	[421,376,446,271]	1	hSpCas9	negative selection	7276650
18856245	18856268	19	-	27260156	HT29	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-2.2951722877013996	[362]	[106,64,85,98]	-9	hSpCas9	negative selection	7340896
18854888	18854911	19	+	27260156	HT29	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.5242407122140755	[944]	[434,513,355,312]	-9	hSpCas9	negative selection	7340897
18854954	18854977	19	-	27260156	HT29	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.328168984767264	[665]	[281,432,338,248]	-9	hSpCas9	negative selection	7340898
18852203	18852226	19	-	27260156	MHHES1	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-1.2400431319738248	[348]	[188,211,193,91]	-9	hSpCas9	negative selection	7397899
18852266	18852289	19	+	27260156	MHHES1	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.6500196840393166	[409]	[400,232,300,251]	-8	hSpCas9	negative selection	7397900
18856236	18856259	19	+	27260156	MHHES1	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.27665139745295464	[297]	[291,382,269,189]	-5	hSpCas9	negative selection	7397901
18856245	18856268	19	-	27260156	MHHES1	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.6375899729708752	[362]	[265,321,356,136]	-8	hSpCas9	negative selection	7462147
18854888	18854911	19	+	27260156	MHHES1	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.5563528058818775	[944]	[927,841,748,458]	-8	hSpCas9	negative selection	7462148
18854954	18854977	19	-	27260156	MHHES1	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.8558207698264578	[665]	[233,476,566,366]	-9	hSpCas9	negative selection	7462149
18852203	18852226	19	-	27260156	MEWO	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.6630052030759269	[348]	[320,170,148]	-8	hSpCas9	negative selection	7519150
18852266	18852289	19	+	27260156	MEWO	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	0.1813954972766972	[409]	[636,426,279]	4	hSpCas9	negative selection	7519151
18856236	18856259	19	+	27260156	MEWO	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.2309474629519967	[297]	[334,333,313]	5	hSpCas9	negative selection	7519152
18856245	18856268	19	-	27260156	MEWO	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.641629914881364	[362]	[269,246,145]	-8	hSpCas9	negative selection	7583398
18854888	18854911	19	+	27260156	MEWO	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.8575023281573739	[944]	[560,462,453]	-9	hSpCas9	negative selection	7583399
18854954	18854977	19	-	27260156	MEWO	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.781327470562976	[665]	[332,318,429]	-9	hSpCas9	negative selection	7583400
18852203	18852226	19	-	27260156	LNCAPCLONEFGC	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.9766302422843581	[348]	[167,200,155,113]	-8	hSpCas9	negative selection	7640401
18852266	18852289	19	+	27260156	LNCAPCLONEFGC	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-1.098363711804749	[409]	[214,146,141,185]	-9	hSpCas9	negative selection	7640402
18856236	18856259	19	+	27260156	LNCAPCLONEFGC	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.10150242421606004	[297]	[212,326,264,198]	-2	hSpCas9	negative selection	7640403
18856245	18856268	19	-	27260156	LNCAPCLONEFGC	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-1.0438617087816517	[362]	[107,172,179,179]	-9	hSpCas9	negative selection	7704649
18854888	18854911	19	+	27260156	LNCAPCLONEFGC	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.398385469442319	[944]	[369,252,286,386]	-9	hSpCas9	negative selection	7704650
18854954	18854977	19	-	27260156	LNCAPCLONEFGC	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.3661473612572959	[665]	[209,269,273,185]	-9	hSpCas9	negative selection	7704651
18852203	18852226	19	-	27260156	PANC0327	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-1.3849996610662023	[348]	[93,110,234,33]	-9	hSpCas9	negative selection	7761652
18852266	18852289	19	+	27260156	PANC0327	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.9370209539751775	[409]	[167,127,186,283]	-8	hSpCas9	negative selection	7761653
18856236	18856259	19	+	27260156	PANC0327	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.15968946695991815	[297]	[242,184,479,284]	2	hSpCas9	negative selection	7761654
18856245	18856268	19	-	27260156	PANC0327	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-1.8951625424417768	[362]	[147,84,79,38]	-9	hSpCas9	negative selection	7825900
18854888	18854911	19	+	27260156	PANC0327	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.849546114639358	[944]	[733,399,504,254]	-8	hSpCas9	negative selection	7825901
18854954	18854977	19	-	27260156	PANC0327	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.1750378243893929	[665]	[198,460,171,184]	-9	hSpCas9	negative selection	7825902
18852203	18852226	19	-	27260156	NCIH2009	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.6628063530014722	[348]	[249,197,465]	-7	hSpCas9	negative selection	7882903
18852266	18852289	19	+	27260156	NCIH2009	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-1.2161827598483546	[409]	[352,262,143]	-8	hSpCas9	negative selection	7882904
18856236	18856259	19	+	27260156	NCIH2009	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.22107630848943305	[297]	[431,399,252]	-3	hSpCas9	negative selection	7882905
18856245	18856268	19	-	27260156	NCIH2009	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-1.743994590744511	[362]	[317,90,78]	-9	hSpCas9	negative selection	7947151
18854888	18854911	19	+	27260156	NCIH2009	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.1314919941061015	[944]	[944,524,405]	-8	hSpCas9	negative selection	7947152
18854954	18854977	19	-	27260156	NCIH2009	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.9197309799558255	[665]	[424,522,512]	-8	hSpCas9	negative selection	7947153
18852203	18852226	19	-	27260156	NCIH1373	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-1.0599300691544449	[348]	[149,122,78,108]	-8	hSpCas9	negative selection	8004154
18852266	18852289	19	+	27260156	NCIH1373	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-2.3805427982692295	[409]	[139,75,86,14]	-9	hSpCas9	negative selection	8004155
18856236	18856259	19	+	27260156	NCIH1373	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.7127273891728622	[297]	[367,218,111,35]	-6	hSpCas9	negative selection	8004156
18856245	18856268	19	-	27260156	NCIH1373	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-1.4436079823631784	[362]	[183,114,207,24]	-8	hSpCas9	negative selection	8068402
18854888	18854911	19	+	27260156	NCIH1373	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.4514143633512049	[944]	[491,268,534,70]	-9	hSpCas9	negative selection	8068403
18854954	18854977	19	-	27260156	NCIH1373	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.0188543429288608	[665]	[252,530,420,57]	-8	hSpCas9	negative selection	8068404
18852203	18852226	19	-	27260156	PATU8902	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.9422469482057275	[348]	[143,644,48,223]	-7	hSpCas9	negative selection	8125405
18852266	18852289	19	+	27260156	PATU8902	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-3.5052758964623987	[409]	[76,48,28,50]	-9	hSpCas9	negative selection	8125406
18856236	18856259	19	+	27260156	PATU8902	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.7801851639545639	[297]	[498,206,95,190]	-6	hSpCas9	negative selection	8125407
18856245	18856268	19	-	27260156	PATU8902	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.8655672590339418	[362]	[450,433,173,45]	-7	hSpCas9	negative selection	8189653
18854888	18854911	19	+	27260156	PATU8902	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-2.441431402364677	[944]	[278,224,287,151]	-9	hSpCas9	negative selection	8189654
18854954	18854977	19	-	27260156	PATU8902	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.9141100601308612	[665]	[630,915,216,241]	-7	hSpCas9	negative selection	8189655
18852203	18852226	19	-	27260156	PANC1	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-1.1482972274544752	[348]	[162,72,157,131]	-8	hSpCas9	negative selection	8246656
18852266	18852289	19	+	27260156	PANC1	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-1.3921113509560559	[409]	[123,135,146,128]	-9	hSpCas9	negative selection	8246657
18856236	18856259	19	+	27260156	PANC1	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.3906295881549905	[297]	[187,180,203,200]	-6	hSpCas9	negative selection	8246658
18856245	18856268	19	-	27260156	PANC1	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-1.9758341389044292	[362]	[55,111,95,61]	-9	hSpCas9	negative selection	8310904
18854888	18854911	19	+	27260156	PANC1	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.9181315251878677	[944]	[174,220,214,241]	-9	hSpCas9	negative selection	8310905
18854954	18854977	19	-	27260156	PANC1	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.5825046212719847	[665]	[140,279,68,274]	-9	hSpCas9	negative selection	8310906
18852203	18852226	19	-	27260156	PANC0813	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-1.3693699957057208	[348]	[154,118,195,163]	-9	hSpCas9	negative selection	8367907
18852266	18852289	19	+	27260156	PANC0813	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-1.852378731638203	[409]	[147,42,123,214]	-9	hSpCas9	negative selection	8367908
18856236	18856259	19	+	27260156	PANC0813	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.4540955417642786	[297]	[176,220,293,318]	-6	hSpCas9	negative selection	8367909
18856245	18856268	19	-	27260156	PANC0813	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-1.2855676940277405	[362]	[204,167,101,223]	-9	hSpCas9	negative selection	8432155
18854888	18854911	19	+	27260156	PANC0813	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.662695839240068	[944]	[405,406,338,259]	-9	hSpCas9	negative selection	8432156
18854954	18854977	19	-	27260156	PANC0813	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.3076379496443657	[665]	[422,205,265,374]	-9	hSpCas9	negative selection	8432157
18852203	18852226	19	-	27260156	RDES	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.572833603259472	[348]	[128,325,242,421]	-7	hSpCas9	negative selection	8489158
18852266	18852289	19	+	27260156	RDES	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.7839323762320805	[409]	[195,249,385,279]	-8	hSpCas9	negative selection	8489159
18856236	18856259	19	+	27260156	RDES	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.3585046522225031	[297]	[417,331,503,518]	6	hSpCas9	negative selection	8489160
18856245	18856268	19	-	27260156	RDES	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.6044759256835297	[362]	[282,214,296,302]	-8	hSpCas9	negative selection	8553406
18854888	18854911	19	+	27260156	RDES	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.1628882380503025	[944]	[406,455,518,579]	-9	hSpCas9	negative selection	8553407
18854954	18854977	19	-	27260156	RDES	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.289349827085028	[665]	[230,184,324,574]	-9	hSpCas9	negative selection	8553408
18852203	18852226	19	-	27260156	PC3	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.4565296484162118	[348]	[159,260,404,262]	-8	hSpCas9	negative selection	8610409
18852266	18852289	19	+	27260156	PC3	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.6158025797111651	[409]	[183,207,359,366]	-8	hSpCas9	negative selection	8610410
18856236	18856259	19	+	27260156	PC3	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.3577942643079425	[297]	[282,382,576,353]	7	hSpCas9	negative selection	8610411
18856245	18856268	19	-	27260156	PC3	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.35254557972106776	[362]	[135,192,475,459]	-7	hSpCas9	negative selection	8674657
18854888	18854911	19	+	27260156	PC3	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.7169638056198168	[944]	[417,660,571,640]	-9	hSpCas9	negative selection	8674658
18854954	18854977	19	-	27260156	PC3	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.5844215054173905	[665]	[409,322,929,249]	-8	hSpCas9	negative selection	8674659
18852203	18852226	19	-	27260156	PATU8988T	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-1.1200681811390951	[348]	[153,127,157,179]	-9	hSpCas9	negative selection	8731660
18852266	18852289	19	+	27260156	PATU8988T	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.296750645665812	[409]	[510,344,233,192]	-5	hSpCas9	negative selection	8731661
18856236	18856259	19	+	27260156	PATU8988T	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.28746074915997843	[297]	[371,282,301,450]	5	hSpCas9	negative selection	8731662
18856245	18856268	19	-	27260156	PATU8988T	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.6891103365071218	[362]	[229,229,278,123]	-8	hSpCas9	negative selection	8795908
18854888	18854911	19	+	27260156	PATU8988T	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.206230087402714	[944]	[263,460,340,534]	-9	hSpCas9	negative selection	8795909
18854954	18854977	19	-	27260156	PATU8988T	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.5995218334407227	[665]	[457,412,568,240]	-7	hSpCas9	negative selection	8795910
18852203	18852226	19	-	27260156	T47D	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.6395755754363902	[348]	[273,253,287,226]	-8	hSpCas9	negative selection	8852911
18852266	18852289	19	+	27260156	T47D	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.8728786050151847	[409]	[241,243,276,281]	-9	hSpCas9	negative selection	8852912
18856236	18856259	19	+	27260156	T47D	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.12694074816126433	[297]	[329,358,401,427]	2	hSpCas9	negative selection	8852913
18856245	18856268	19	-	27260156	T47D	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-1.3264732865144888	[362]	[170,153,171,178]	-9	hSpCas9	negative selection	8917159
18854888	18854911	19	+	27260156	T47D	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.8968608805924723	[944]	[506,575,612,671]	-9	hSpCas9	negative selection	8917160
18854954	18854977	19	-	27260156	T47D	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.099143784866302	[665]	[408,330,322,389]	-9	hSpCas9	negative selection	8917161
18852203	18852226	19	-	27260156	SU8686	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-1.2575587916989273	[348]	[104,217,113,132]	-9	hSpCas9	negative selection	8974162
18852266	18852289	19	+	27260156	SU8686	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-1.5986226378821997	[409]	[80,146,132,187]	-9	hSpCas9	negative selection	8974163
18856236	18856259	19	+	27260156	SU8686	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.17761121223983722	[297]	[273,199,240,347]	-3	hSpCas9	negative selection	8974164
18856245	18856268	19	-	27260156	SU8686	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-2.1982760476955154	[362]	[37,96,64,121]	-9	hSpCas9	negative selection	9038410
18854888	18854911	19	+	27260156	SU8686	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-1.525394667519612	[944]	[267,345,267,437]	-9	hSpCas9	negative selection	9038411
18854954	18854977	19	-	27260156	SU8686	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-1.573568896008322	[665]	[280,187,144,275]	-9	hSpCas9	negative selection	9038412
18852203	18852226	19	-	27260156	SKES1	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.44012321604989146	[348]	[341,306,197,201]	-7	hSpCas9	negative selection	9095413
18852266	18852289	19	+	27260156	SKES1	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.4600998813010265	[409]	[371,235,291,289]	-7	hSpCas9	negative selection	9095414
18856236	18856259	19	+	27260156	SKES1	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.027481571361542834	[297]	[274,447,304,205]	0	hSpCas9	negative selection	9095415
18856245	18856268	19	-	27260156	SKES1	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.43474665138647134	[362]	[345,287,262,193]	-7	hSpCas9	negative selection	9159661
18854888	18854911	19	+	27260156	SKES1	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.6032067511626482	[944]	[777,563,582,571]	-8	hSpCas9	negative selection	9159662
18854954	18854977	19	-	27260156	SKES1	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.6593385946820141	[665]	[420,509,358,401]	-8	hSpCas9	negative selection	9159663
18852203	18852226	19	-	27260156	TOV112D	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.2422643685869077	[348]	[436,330,167,266]	-5	hSpCas9	negative selection	9216664
18852266	18852289	19	+	27260156	TOV112D	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-1.3313975893102554	[409]	[165,219,201,80]	-9	hSpCas9	negative selection	9216665
18856236	18856259	19	+	27260156	TOV112D	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.4355550706685568	[297]	[575,516,364,203]	7	hSpCas9	negative selection	9216666
18856245	18856268	19	-	27260156	TOV112D	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.7166250989014185	[362]	[247,231,170,237]	-8	hSpCas9	negative selection	9280912
18854888	18854911	19	+	27260156	TOV112D	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.8586338441698096	[944]	[371,689,579,474]	-9	hSpCas9	negative selection	9280913
18854954	18854977	19	-	27260156	TOV112D	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.7092378216183298	[665]	[391,801,273,262]	-8	hSpCas9	negative selection	9280914
18852203	18852226	19	-	27260156	TC71	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.4544636638742402	[348]	[271,277,280,259]	-8	hSpCas9	negative selection	9337915
18852266	18852289	19	+	27260156	TC71	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.4851042866555815	[409]	[286,255,265,457]	-8	hSpCas9	negative selection	9337916
18856236	18856259	19	+	27260156	TC71	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	0.21804722491944611	[297]	[353,400,349,382]	5	hSpCas9	negative selection	9337917
18856245	18856268	19	-	27260156	TC71	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.4140120081534195	[362]	[324,299,258,283]	-8	hSpCas9	negative selection	9402163
18854888	18854911	19	+	27260156	TC71	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.578290801299583	[944]	[743,828,598,533]	-9	hSpCas9	negative selection	9402164
18854954	18854977	19	-	27260156	TC71	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.5571186509713366	[665]	[492,505,452,489]	-9	hSpCas9	negative selection	9402165
18852203	18852226	19	-	27260156	TC32	viability	GGTAGGCGTCCTCGTACCGCAGG	UPF1	ENSG00000005007	-0.2263813382594081	[348]	[353,83,369,384]	-4	hSpCas9	negative selection	9459166
18852266	18852289	19	+	27260156	TC32	viability	CGACTACGACAAGAAGCTGAAGG	UPF1	ENSG00000005007	-0.4696908948565752	[409]	[222,279,327,278]	-7	hSpCas9	negative selection	9459167
18856236	18856259	19	+	27260156	TC32	viability	TGTCGTCTGCCGACGAGAAGCGG	UPF1	ENSG00000005007	-0.09228655321106716	[297]	[212,193,406,279]	-2	hSpCas9	negative selection	9459168
18856245	18856268	19	-	27260156	TC32	viability	GGCCCGGTACCGCTTCTCGTCGG	UPF1	ENSG00000005007	-0.6568393362314848	[362]	[167,180,324,216]	-8	hSpCas9	negative selection	9523414
18854888	18854911	19	+	27260156	TC32	viability	CGCATTGAAAACGTTTGCCGTGG	UPF1	ENSG00000005007	-0.5921108345413848	[944]	[631,408,745,625]	-8	hSpCas9	negative selection	9523415
18854954	18854977	19	-	27260156	TC32	viability	TGATTACGTCCTCCACCTCGTGG	UPF1	ENSG00000005007	-0.5116517766056016	[665]	[436,397,469,443]	-7	hSpCas9	negative selection	9523416
18832197	18832220	19	+	27869803	HPAFII	viability after 27 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-3.982387344761824	[1535]	[7,86,NaN]	-9	hSpCas9	negative selection	9566539
18846039	18846062	19	-	27869803	HPAFII	viability after 27 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.43132428830762937	[290]	[167,67,NaN]	-3	hSpCas9	negative selection	9566540
18847767	18847790	19	-	27869803	HPAFII	viability after 27 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-5.930400540751869	[115]	[0,0,NaN]	-9	hSpCas9	negative selection	9566541
18850108	18850131	19	+	27869803	HPAFII	viability after 27 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-0.03990776120966555	[354]	[234,136,NaN]	0	hSpCas9	negative selection	9566542
18850772	18850795	19	-	27869803	HPAFII	viability after 27 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-4.377341215205969	[344]	[11,5,NaN]	-9	hSpCas9	negative selection	9566543
18852246	18852269	19	-	27869803	HPAFII	viability after 27 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-3.7079623101201373	[408]	[34,0,NaN]	-9	hSpCas9	negative selection	9566544
18832197	18832220	19	+	27869803	HPAFII	viability after 15 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-2.8059049674907888	[1535]	[203,255,NaN]	-9	hSpCas9	negative selection	9648988
18846039	18846062	19	-	27869803	HPAFII	viability after 15 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.08147306733217846	[290]	[548,137,NaN]	-1	hSpCas9	negative selection	9648989
18847767	18847790	19	-	27869803	HPAFII	viability after 15 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-5.417489116800365	[115]	[5,0,NaN]	-9	hSpCas9	negative selection	9648990
18850108	18850131	19	+	27869803	HPAFII	viability after 15 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-0.6616606273230787	[354]	[419,129,NaN]	-6	hSpCas9	negative selection	9648991
18850772	18850795	19	-	27869803	HPAFII	viability after 15 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-2.9615157475684804	[344]	[54,42,NaN]	-9	hSpCas9	negative selection	9648992
18852246	18852269	19	-	27869803	HPAFII	viability after 15 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-4.716507649546677	[408]	[41,0,NaN]	-9	hSpCas9	negative selection	9648993
18832197	18832220	19	+	27869803	ASPC1	viability after 36 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-4.356290890732191	[3242]	[158,0,24]	-9	hSpCas9	negative selection	9731437
18846039	18846062	19	-	27869803	ASPC1	viability after 36 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	0.46467893411114986	[673]	[361,155,428]	4	hSpCas9	negative selection	9731438
18847767	18847790	19	-	27869803	ASPC1	viability after 36 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-3.6372436086027724	[217]	[0,16,0]	-9	hSpCas9	negative selection	9731439
18850108	18850131	19	+	27869803	ASPC1	viability after 36 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	0.41358472420096193	[1016]	[1006,428,127]	4	hSpCas9	negative selection	9731440
18850772	18850795	19	-	27869803	ASPC1	viability after 36 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-0.21587505079087177	[813]	[156,194,342]	-2	hSpCas9	negative selection	9731441
18852246	18852269	19	-	27869803	ASPC1	viability after 36 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-4.277275769970218	[900]	[29,22,0]	-9	hSpCas9	negative selection	9731442
18832197	18832220	19	+	27869803	PATU8988S	viability after 35 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-3.4142917951179017	[2883]	[86,130,NaN]	-9	hSpCas9	negative selection	9813886
18846039	18846062	19	-	27869803	PATU8988S	viability after 35 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.24973171014290976	[672]	[213,241,NaN]	-3	hSpCas9	negative selection	9813887
18847767	18847790	19	-	27869803	PATU8988S	viability after 35 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-5.098992257154514	[169]	[0,2,NaN]	-9	hSpCas9	negative selection	9813888
18850108	18850131	19	+	27869803	PATU8988S	viability after 35 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-0.49536403620029246	[664]	[186,192,NaN]	-5	hSpCas9	negative selection	9813889
18850772	18850795	19	-	27869803	PATU8988S	viability after 35 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-3.970896804851832	[779]	[34,4,NaN]	-9	hSpCas9	negative selection	9813890
18852246	18852269	19	-	27869803	PATU8988S	viability after 35 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-6.673862147041452	[886]	[2,3,NaN]	-9	hSpCas9	negative selection	9813891
18832197	18832220	19	+	27869803	PATU8988S	viability after 31 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-2.8928265364866004	[2883]	[116,202,NaN]	-9	hSpCas9	negative selection	9896335
18846039	18846062	19	-	27869803	PATU8988S	viability after 31 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.30620308038400196	[672]	[198,239,NaN]	-3	hSpCas9	negative selection	9896336
18847767	18847790	19	-	27869803	PATU8988S	viability after 31 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-4.172330298749468	[169]	[1,5,NaN]	-9	hSpCas9	negative selection	9896337
18850108	18850131	19	+	27869803	PATU8988S	viability after 31 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-0.1357244029779767	[664]	[221,265,NaN]	-1	hSpCas9	negative selection	9896338
18850772	18850795	19	-	27869803	PATU8988S	viability after 31 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-3.62307277452552	[779]	[37,8,NaN]	-9	hSpCas9	negative selection	9896339
18852246	18852269	19	-	27869803	PATU8988S	viability after 31 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-7.55572965691283	[886]	[0,2,NaN]	-9	hSpCas9	negative selection	9896340
18832197	18832220	19	+	27869803	HPAFII	viability after 35 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-4.428678508903941	[1535]	[13,60,NaN]	-9	hSpCas9	negative selection	9978784
18846039	18846062	19	-	27869803	HPAFII	viability after 35 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.22374293150757885	[290]	[199,42,NaN]	-1	hSpCas9	negative selection	9978785
18847767	18847790	19	-	27869803	HPAFII	viability after 35 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-5.875892442130898	[115]	[0,0,NaN]	-9	hSpCas9	negative selection	9978786
18850108	18850131	19	+	27869803	HPAFII	viability after 35 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	-0.03167863415273525	[354]	[156,196,NaN]	0	hSpCas9	negative selection	9978787
18850772	18850795	19	-	27869803	HPAFII	viability after 35 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-4.1604782780343825	[344]	[13,4,NaN]	-9	hSpCas9	negative selection	9978788
18852246	18852269	19	-	27869803	HPAFII	viability after 35 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-5.039331503114074	[408]	[10,0,NaN]	-9	hSpCas9	negative selection	9978789
18832197	18832220	19	+	27869803	HPAFII	viability after 31 days	ACCCGGAGGCACCATGAGCGTGG	UPF1	ENSG00000005007	-4.919786427993534	[1535]	[27,28,NaN]	-9	hSpCas9	negative selection	10061233
18846039	18846062	19	-	27869803	HPAFII	viability after 31 days	AGTTCAACTCAGCCAACAACTGG	UPF1	ENSG00000005007	-0.730184842218835	[290]	[141,50,NaN]	-5	hSpCas9	negative selection	10061234
18847767	18847790	19	-	27869803	HPAFII	viability after 31 days	GGTATTACAGTAAACCACGCAGG	UPF1	ENSG00000005007	-6.024609795452315	[115]	[0,0,NaN]	-9	hSpCas9	negative selection	10061235
18850108	18850131	19	+	27869803	HPAFII	viability after 31 days	CAAAGAGGTGACCCTGCACAAGG	UPF1	ENSG00000005007	0.15020459174967304	[354]	[211,230,NaN]	1	hSpCas9	negative selection	10061236
18850772	18850795	19	-	27869803	HPAFII	viability after 31 days	GGATCTTGACCAGCCAGGACAGG	UPF1	ENSG00000005007	-3.0681528861834453	[344]	[24,20,NaN]	-9	hSpCas9	negative selection	10061237
18852246	18852269	19	-	27869803	HPAFII	viability after 31 days	TCGGCCTCCAGCTTGACCAGGGG	UPF1	ENSG00000005007	-7.237159229985619	[408]	[1,0,NaN]	-9	hSpCas9	negative selection	10061238
18850763	18850786	19	-	28162770	P31FUJ	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-1.9096871945765739	[242]	[75]	-8	hSpCas9	negative selection	10261642
18855014	18855037	19	-	28162770	P31FUJ	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-3.933241922555471	[12]	[0]	-9	hSpCas9	negative selection	10261643
18854942	18854965	19	+	28162770	P31FUJ	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-2.895767217136808	[227]	[35]	-9	hSpCas9	negative selection	10261644
18850112	18850135	19	+	28162770	P31FUJ	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-2.7405968446130746	[90]	[15]	-9	hSpCas9	negative selection	10261645
18850793	18850816	19	-	28162770	P31FUJ	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-2.5450801292680216	[148]	[29]	-8	hSpCas9	negative selection	10261646
18850835	18850858	19	+	28162770	P31FUJ	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-1.44060708952778	[163]	[70]	-7	hSpCas9	negative selection	10261647
18852154	18852177	19	+	28162770	P31FUJ	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-2.7400095476210895	[306]	[53]	-9	hSpCas9	negative selection	10261648
18853249	18853272	19	+	28162770	P31FUJ	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-3.809727386070116	[178]	[14]	-9	hSpCas9	negative selection	10261649
18854656	18854679	19	+	28162770	P31FUJ	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-0.6437353053604858	[350]	[263]	-5	hSpCas9	negative selection	10261650
18854917	18854940	19	-	28162770	P31FUJ	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-3.7771227206381885	[174]	[14]	-9	hSpCas9	negative selection	10261651
18850763	18850786	19	-	28162770	TF1	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10431008
18855014	18855037	19	-	28162770	TF1	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10431009
18854942	18854965	19	+	28162770	TF1	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10431010
18850112	18850135	19	+	28162770	TF1	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10431011
18850793	18850816	19	-	28162770	TF1	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10431012
18850835	18850858	19	+	28162770	TF1	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	NaN	[NaN]	[130]	1	hSpCas9	negative selection	10431013
18852154	18852177	19	+	28162770	TF1	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	NaN	[NaN]	[144]	1	hSpCas9	negative selection	10431014
18853249	18853272	19	+	28162770	TF1	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10431015
18854656	18854679	19	+	28162770	TF1	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10431016
18854917	18854940	19	-	28162770	TF1	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10431017
18850763	18850786	19	-	28162770	SKM1	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-4.011826256902022	[72]	[7]	-9	hSpCas9	negative selection	10600374
18855014	18855037	19	-	28162770	SKM1	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-2.8220016980220053	[3]	[0]	-9	hSpCas9	negative selection	10600375
18854942	18854965	19	+	28162770	SKM1	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-1.143929792909368	[64]	[51]	-7	hSpCas9	negative selection	10600376
18850112	18850135	19	+	28162770	SKM1	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-1.7835275502073697	[36]	[18]	-8	hSpCas9	negative selection	10600377
18850793	18850816	19	-	28162770	SKM1	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-1.3814291066360243	[55]	[37]	-7	hSpCas9	negative selection	10600378
18850835	18850858	19	+	28162770	SKM1	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-2.1257824461991084	[78]	[31]	-8	hSpCas9	negative selection	10600379
18852154	18852177	19	+	28162770	SKM1	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-0.6226928897985988	[53]	[61]	-5	hSpCas9	negative selection	10600380
18853249	18853272	19	+	28162770	SKM1	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-1.1157329010787158	[37]	[30]	-7	hSpCas9	negative selection	10600381
18854656	18854679	19	+	28162770	SKM1	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-0.8408607252733216	[76]	[75]	-6	hSpCas9	negative selection	10600382
18854917	18854940	19	-	28162770	SKM1	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-4.909464539272345	[33]	[1]	-9	hSpCas9	negative selection	10600383
18850763	18850786	19	-	28162770	SKM1	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-4.011826256902022	[72]	[7]	-9	hSpCas9	negative selection	10769740
18855014	18855037	19	-	28162770	SKM1	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-2.8220016980220053	[3]	[0]	-9	hSpCas9	negative selection	10769741
18854942	18854965	19	+	28162770	SKM1	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-1.143929792909368	[64]	[51]	-7	hSpCas9	negative selection	10769742
18850112	18850135	19	+	28162770	SKM1	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-1.7835275502073697	[36]	[18]	-8	hSpCas9	negative selection	10769743
18850793	18850816	19	-	28162770	SKM1	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-1.3814291066360243	[55]	[37]	-7	hSpCas9	negative selection	10769744
18850835	18850858	19	+	28162770	SKM1	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-2.1257824461991084	[78]	[31]	-8	hSpCas9	negative selection	10769745
18852154	18852177	19	+	28162770	SKM1	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-0.6226928897985988	[53]	[61]	-5	hSpCas9	negative selection	10769746
18853249	18853272	19	+	28162770	SKM1	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-1.1157329010787158	[37]	[30]	-7	hSpCas9	negative selection	10769747
18854656	18854679	19	+	28162770	SKM1	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-0.8408607252733216	[76]	[75]	-6	hSpCas9	negative selection	10769748
18854917	18854940	19	-	28162770	SKM1	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-4.909464539272345	[33]	[1]	-9	hSpCas9	negative selection	10769749
18850763	18850786	19	-	28162770	PL21	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-1.4975908163937859	[265]	[40]	-7	hSpCas9	negative selection	10939106
18855014	18855037	19	-	28162770	PL21	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-1.1217884803980427	[9]	[1]	-6	hSpCas9	negative selection	10939107
18854942	18854965	19	+	28162770	PL21	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-0.31356420306201405	[236]	[82]	-2	hSpCas9	negative selection	10939108
18850112	18850135	19	+	28162770	PL21	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-0.8639907229303954	[91]	[21]	-5	hSpCas9	negative selection	10939109
18850793	18850816	19	-	28162770	PL21	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-3.0811464959006964	[174]	[8]	-9	hSpCas9	negative selection	10939110
18850835	18850858	19	+	28162770	PL21	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	0.1613203655987921	[225]	[109]	1	hSpCas9	negative selection	10939111
18852154	18852177	19	+	28162770	PL21	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-1.0239411569998975	[284]	[60]	-6	hSpCas9	negative selection	10939112
18853249	18853272	19	+	28162770	PL21	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-0.00421888401686632	[158]	[68]	0	hSpCas9	negative selection	10939113
18854656	18854679	19	+	28162770	PL21	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	0.018735604603711042	[346]	[152]	0	hSpCas9	negative selection	10939114
18854917	18854940	19	-	28162770	PL21	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-4.242803881359409	[86]	[1]	-9	hSpCas9	negative selection	10939115
18850763	18850786	19	-	28162770	P31FUJ	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-1.9096871945765739	[242]	[75]	-8	hSpCas9	negative selection	11108472
18855014	18855037	19	-	28162770	P31FUJ	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-3.933241922555471	[12]	[0]	-9	hSpCas9	negative selection	11108473
18854942	18854965	19	+	28162770	P31FUJ	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-2.895767217136808	[227]	[35]	-9	hSpCas9	negative selection	11108474
18850112	18850135	19	+	28162770	P31FUJ	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-2.7405968446130746	[90]	[15]	-9	hSpCas9	negative selection	11108475
18850793	18850816	19	-	28162770	P31FUJ	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-2.5450801292680216	[148]	[29]	-8	hSpCas9	negative selection	11108476
18850835	18850858	19	+	28162770	P31FUJ	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-1.44060708952778	[163]	[70]	-7	hSpCas9	negative selection	11108477
18852154	18852177	19	+	28162770	P31FUJ	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-2.7400095476210895	[306]	[53]	-9	hSpCas9	negative selection	11108478
18853249	18853272	19	+	28162770	P31FUJ	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-3.809727386070116	[178]	[14]	-9	hSpCas9	negative selection	11108479
18854656	18854679	19	+	28162770	P31FUJ	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-0.6437353053604858	[350]	[263]	-5	hSpCas9	negative selection	11108480
18854917	18854940	19	-	28162770	P31FUJ	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-3.7771227206381885	[174]	[14]	-9	hSpCas9	negative selection	11108481
18850763	18850786	19	-	28162770	OCIAML5	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-2.714563047114062	[119]	[32]	-8	hSpCas9	negative selection	11277838
18855014	18855037	19	-	28162770	OCIAML5	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-1.4370290715851537	[2]	[1]	-7	hSpCas9	negative selection	11277839
18854942	18854965	19	+	28162770	OCIAML5	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-1.1490483086211285	[128]	[104]	-6	hSpCas9	negative selection	11277840
18850112	18850135	19	+	28162770	OCIAML5	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-1.3320595119836107	[52]	[37]	-6	hSpCas9	negative selection	11277841
18850793	18850816	19	-	28162770	OCIAML5	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-1.7286841553587147	[111]	[60]	-7	hSpCas9	negative selection	11277842
18850835	18850858	19	+	28162770	OCIAML5	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-2.2584909398381328	[166]	[62]	-8	hSpCas9	negative selection	11277843
18852154	18852177	19	+	28162770	OCIAML5	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-0.6610182778559307	[112]	[128]	-4	hSpCas9	negative selection	11277844
18853249	18853272	19	+	28162770	OCIAML5	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-1.3960018033250985	[155]	[106]	-7	hSpCas9	negative selection	11277845
18854656	18854679	19	+	28162770	OCIAML5	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-1.1739946657513594	[174]	[139]	-6	hSpCas9	negative selection	11277846
18854917	18854940	19	-	28162770	OCIAML5	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-2.4749969217841734	[76]	[24]	-8	hSpCas9	negative selection	11277847
18850763	18850786	19	-	28162770	EOL1	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-1.448006396386796	[434]	[83]	-7	hSpCas9	negative selection	11447204
18855014	18855037	19	-	28162770	EOL1	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	1.339585270849378	[5]	[7]	9	hSpCas9	negative selection	11447205
18854942	18854965	19	+	28162770	EOL1	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-1.6644843934596685	[354]	[58]	-8	hSpCas9	negative selection	11447206
18850112	18850135	19	+	28162770	EOL1	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-1.2211296836251004	[176]	[39]	-7	hSpCas9	negative selection	11447207
18850793	18850816	19	-	28162770	EOL1	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-2.310228374221746	[272]	[28]	-8	hSpCas9	negative selection	11447208
18850835	18850858	19	+	28162770	EOL1	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-1.5283111931432765	[437]	[79]	-7	hSpCas9	negative selection	11447209
18852154	18852177	19	+	28162770	EOL1	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-1.786422614062727	[274]	[41]	-8	hSpCas9	negative selection	11447210
18853249	18853272	19	+	28162770	EOL1	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-5.029648538816341	[185]	[2]	-9	hSpCas9	negative selection	11447211
18854656	18854679	19	+	28162770	EOL1	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-0.9362464094485301	[384]	[105]	-6	hSpCas9	negative selection	11447212
18854917	18854940	19	-	28162770	EOL1	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-6.441774442675281	[164]	[0]	-9	hSpCas9	negative selection	11447213
18850763	18850786	19	-	28162770	MOLM13	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-1.8147495822287265	[325]	[66]	-7	hSpCas9	negative selection	11616570
18855014	18855037	19	-	28162770	MOLM13	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-1.1170731191765775	[20]	[6]	-5	hSpCas9	negative selection	11616571
18854942	18854965	19	+	28162770	MOLM13	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-0.14003426761988866	[284]	[186]	-1	hSpCas9	negative selection	11616572
18850112	18850135	19	+	28162770	MOLM13	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-0.2101825235680589	[151]	[94]	-1	hSpCas9	negative selection	11616573
18850793	18850816	19	-	28162770	MOLM13	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-2.5078630722087443	[235]	[29]	-8	hSpCas9	negative selection	11616574
18850835	18850858	19	+	28162770	MOLM13	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-1.1220223351483105	[291]	[96]	-5	hSpCas9	negative selection	11616575
18852154	18852177	19	+	28162770	MOLM13	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-1.3105528485977866	[246]	[71]	-6	hSpCas9	negative selection	11616576
18853249	18853272	19	+	28162770	MOLM13	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-3.422881548700663	[266]	[17]	-8	hSpCas9	negative selection	11616577
18854656	18854679	19	+	28162770	MOLM13	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-2.5022949640198595	[430]	[54]	-8	hSpCas9	negative selection	11616578
18854917	18854940	19	-	28162770	MOLM13	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-2.8540387133427836	[149]	[14]	-8	hSpCas9	negative selection	11616579
18850763	18850786	19	-	28162770	HEL	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-2.0373809017611393	[281]	[43]	-8	hSpCas9	negative selection	11785936
18855014	18855037	19	-	28162770	HEL	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-3.8166927866369402	[21]	[0]	-9	hSpCas9	negative selection	11785937
18854942	18854965	19	+	28162770	HEL	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-0.08855801207915726	[253]	[152]	0	hSpCas9	negative selection	11785938
18850112	18850135	19	+	28162770	HEL	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-0.1671582846197005	[141]	[80]	-1	hSpCas9	negative selection	11785939
18850793	18850816	19	-	28162770	HEL	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-2.250345964083131	[259]	[34]	-8	hSpCas9	negative selection	11785940
18850835	18850858	19	+	28162770	HEL	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-0.7722986672784867	[311]	[116]	-5	hSpCas9	negative selection	11785941
18852154	18852177	19	+	28162770	HEL	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-1.2065297317906416	[226]	[62]	-6	hSpCas9	negative selection	11785942
18853249	18853272	19	+	28162770	HEL	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-2.500219121841686	[211]	[23]	-8	hSpCas9	negative selection	11785943
18854656	18854679	19	+	28162770	HEL	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-1.6667700036329376	[346]	[69]	-7	hSpCas9	negative selection	11785944
18854917	18854940	19	-	28162770	HEL	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-1.8426879951698845	[139]	[24]	-7	hSpCas9	negative selection	11785945
18850763	18850786	19	-	28162770	MV411	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-2.2550627897464075	[203]	[35]	-8	hSpCas9	negative selection	11955302
18855014	18855037	19	-	28162770	MV411	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-1.3375249499383806	[2]	[0]	-7	hSpCas9	negative selection	11955303
18854942	18854965	19	+	28162770	MV411	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-1.8329358656812444	[202]	[47]	-8	hSpCas9	negative selection	11955304
18850112	18850135	19	+	28162770	MV411	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	0.45524243589617697	[70]	[81]	4	hSpCas9	negative selection	11955305
18850793	18850816	19	-	28162770	MV411	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-2.432682182978721	[140]	[21]	-8	hSpCas9	negative selection	11955306
18850835	18850858	19	+	28162770	MV411	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-2.528347292273959	[225]	[32]	-8	hSpCas9	negative selection	11955307
18852154	18852177	19	+	28162770	MV411	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-1.6525666592405035	[208]	[55]	-7	hSpCas9	negative selection	11955308
18853249	18853272	19	+	28162770	MV411	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-2.5046349357736393	[127]	[18]	-8	hSpCas9	negative selection	11955309
18854656	18854679	19	+	28162770	MV411	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-0.8937385121779189	[235]	[106]	-6	hSpCas9	negative selection	11955310
18854917	18854940	19	-	28162770	MV411	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-5.086463185770663	[120]	[2]	-9	hSpCas9	negative selection	11955311
18850763	18850786	19	-	28162770	MONOMAC1	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-2.7376052284222565	[127]	[21]	-9	hSpCas9	negative selection	12124668
18855014	18855037	19	-	28162770	MONOMAC1	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-2.197036847059554	[3]	[0]	-9	hSpCas9	negative selection	12124669
18854942	18854965	19	+	28162770	MONOMAC1	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-0.49148420552480904	[129]	[105]	-4	hSpCas9	negative selection	12124670
18850112	18850135	19	+	28162770	MONOMAC1	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-1.0901216431430418	[51]	[27]	-7	hSpCas9	negative selection	12124671
18850793	18850816	19	-	28162770	MONOMAC1	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-1.0011166370842968	[109]	[62]	-7	hSpCas9	negative selection	12124672
18850835	18850858	19	+	28162770	MONOMAC1	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-0.4262376578174721	[176]	[150]	-4	hSpCas9	negative selection	12124673
18852154	18852177	19	+	28162770	MONOMAC1	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	0.03806662602644825	[112]	[132]	0	hSpCas9	negative selection	12124674
18853249	18853272	19	+	28162770	MONOMAC1	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-0.6071251303666642	[96]	[72]	-5	hSpCas9	negative selection	12124675
18854656	18854679	19	+	28162770	MONOMAC1	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-1.0629001744080175	[194]	[106]	-7	hSpCas9	negative selection	12124676
18854917	18854940	19	-	28162770	MONOMAC1	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-2.763383669613363	[76]	[12]	-9	hSpCas9	negative selection	12124677
18850763	18850786	19	-	28162770	OCIAML2	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-2.785503162595573	[50]	[40]	-9	hSpCas9	negative selection	12294034
18855014	18855037	19	-	28162770	OCIAML2	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-4.0555923259633175	[2]	[0]	-9	hSpCas9	negative selection	12294035
18854942	18854965	19	+	28162770	OCIAML2	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-1.088160188419748	[27]	[72]	-6	hSpCas9	negative selection	12294036
18850112	18850135	19	+	28162770	OCIAML2	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-1.129592907407094	[29]	[75]	-6	hSpCas9	negative selection	12294037
18850793	18850816	19	-	28162770	OCIAML2	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-1.7252026523277588	[33]	[56]	-8	hSpCas9	negative selection	12294038
18850835	18850858	19	+	28162770	OCIAML2	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-1.2371396950223827	[36]	[86]	-7	hSpCas9	negative selection	12294039
18852154	18852177	19	+	28162770	OCIAML2	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-2.505395243402838	[41]	[40]	-8	hSpCas9	negative selection	12294040
18853249	18853272	19	+	28162770	OCIAML2	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-1.9852029980719197	[24]	[34]	-8	hSpCas9	negative selection	12294041
18854656	18854679	19	+	28162770	OCIAML2	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	-1.0599975050833186	[40]	[108]	-6	hSpCas9	negative selection	12294042
18854917	18854940	19	-	28162770	OCIAML2	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-4.672263686411812	[22]	[4]	-9	hSpCas9	negative selection	12294043
18850763	18850786	19	-	28162770	OCIAML3	viability	CCAGCCAGGACAGGAAGCAGCGG	UPF1	ENSG00000005007	-2.3309732344903695	[84]	[50]	-9	hSpCas9	negative selection	12463400
18855014	18855037	19	-	28162770	OCIAML3	viability	GGGAGTGGTTGAGGTCGGGGAGG	UPF1	ENSG00000005007	-2.33097323449037	[4]	[2]	-9	hSpCas9	negative selection	12463401
18854942	18854965	19	+	28162770	OCIAML3	viability	CAAGCTGTTGGGCCACGAGGTGG	UPF1	ENSG00000005007	-1.393310290087034	[66]	[76]	-7	hSpCas9	negative selection	12463402
18850112	18850135	19	+	28162770	OCIAML3	viability	GAGGTGACCCTGCACAAGGACGG	UPF1	ENSG00000005007	-0.6121549870344225	[39]	[78]	-5	hSpCas9	negative selection	12463403
18850793	18850816	19	-	28162770	OCIAML3	viability	GCAGCTGCTCCTGCTCGGAGGGG	UPF1	ENSG00000005007	-2.154722594798642	[58]	[39]	-8	hSpCas9	negative selection	12463404
18850835	18850858	19	+	28162770	OCIAML3	viability	ACAGCAGATCAACAAGCTGGAGG	UPF1	ENSG00000005007	-0.7064823695825757	[59]	[110]	-5	hSpCas9	negative selection	12463405
18852154	18852177	19	+	28162770	OCIAML3	viability	TGGAGGACCTGGAGAAGCCGGGG	UPF1	ENSG00000005007	-1.6935433138750775	[74]	[69]	-8	hSpCas9	negative selection	12463406
18853249	18853272	19	+	28162770	OCIAML3	viability	AAGACATGCGGCTCATGCAGGGG	UPF1	ENSG00000005007	-2.4737134066064517	[45]	[24]	-9	hSpCas9	negative selection	12463407
18854656	18854679	19	+	28162770	OCIAML3	viability	GGTGACTCACAACTTCCAGGTGG	UPF1	ENSG00000005007	0.06524864274430686	[81]	[258]	0	hSpCas9	negative selection	12463408
18854917	18854940	19	-	28162770	OCIAML3	viability	GTAGATGTAGCCAGACACCGAGG	UPF1	ENSG00000005007	-3.4519886354517357	[28]	[7]	-9	hSpCas9	negative selection	12463409