Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:7436
• Symbol:VLDLR
• Description:very low density lipoprotein receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/VLDLR

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
2641478	2641501	9	+	26472758	Jiyoye	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	1.7291034763932358	[57]	[144]	8	hSpCas9	negative selection	179812
2643203	2643226	9	-	26472758	Jiyoye	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	0.15341878926009042	[92]	[77]	1	hSpCas9	negative selection	179813
2643234	2643257	9	+	26472758	Jiyoye	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.31894819849413825	[235]	[221]	2	hSpCas9	negative selection	179814
2643319	2643342	9	-	26472758	Jiyoye	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.7412440392654478	[141]	[178]	5	hSpCas9	negative selection	179815
2643457	2643480	9	+	26472758	Jiyoye	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	-0.05379840193982943	[350]	[254]	0	hSpCas9	negative selection	179816
2644832	2644855	9	+	26472758	Jiyoye	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	0.8263289892569493	[174]	[233]	6	hSpCas9	negative selection	179817
2646542	2646565	9	-	26472758	Jiyoye	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	-1.0367432377600994	[369]	[135]	-6	hSpCas9	negative selection	179818
2635551	2635574	9	+	26472758	Jiyoye	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	2.935554353860662	[12]	[74]	9	hSpCas9	negative selection	179819
2639933	2639956	9	+	26472758	Jiyoye	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	1.760812336120574	[17]	[45]	8	hSpCas9	negative selection	179820
2641391	2641414	9	+	26472758	Jiyoye	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	-0.4449791505227326	[138]	[76]	-3	hSpCas9	negative selection	179821
2641478	2641501	9	+	26472758	KBM7	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-1.0293020250664837	[491,347]	[94,95]	-7	hSpCas9	negative selection	370930
2643203	2643226	9	-	26472758	KBM7	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	0.690941438219813	[378,576]	[470,283]	7	hSpCas9	negative selection	370931
2643234	2643257	9	+	26472758	KBM7	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.4607042739664938	[764,540]	[526,318]	5	hSpCas9	negative selection	370932
2643319	2643342	9	-	26472758	KBM7	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	-0.30699801460210985	[696,595]	[330,167]	-3	hSpCas9	negative selection	370933
2643457	2643480	9	+	26472758	KBM7	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	-0.0036836885054027935	[1124,842]	[400,506]	0	hSpCas9	negative selection	370934
2644832	2644855	9	+	26472758	KBM7	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	-0.026249408195143098	[1018,781]	[568,271]	0	hSpCas9	negative selection	370935
2646542	2646565	9	-	26472758	KBM7	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	0.5803247045557656	[591,483]	[419,336]	6	hSpCas9	negative selection	370936
2635551	2635574	9	+	26472758	KBM7	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	-0.4593075954193999	[214,111]	[65,43]	-4	hSpCas9	negative selection	370937
2639933	2639956	9	+	26472758	KBM7	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	-0.0564648382696884	[310,316]	[155,130]	0	hSpCas9	negative selection	370938
2641391	2641414	9	+	26472758	KBM7	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	0.3586704375942835	[395,464]	[367,168]	4	hSpCas9	negative selection	370939
2641478	2641501	9	+	26472758	Raji	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-1.4895516070136328	[120]	[9]	-8	hSpCas9	negative selection	562048
2643203	2643226	9	-	26472758	Raji	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	0.7519028807752104	[260]	[101]	7	hSpCas9	negative selection	562049
2643234	2643257	9	+	26472758	Raji	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.30371366012385126	[390]	[111]	3	hSpCas9	negative selection	562050
2643319	2643342	9	-	26472758	Raji	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.8307794309957275	[234]	[96]	7	hSpCas9	negative selection	562051
2643457	2643480	9	+	26472758	Raji	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.30002861331599545	[300]	[85]	3	hSpCas9	negative selection	562052
2644832	2644855	9	+	26472758	Raji	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	0.3000286133159954	[328]	[93]	3	hSpCas9	negative selection	562053
2646542	2646565	9	-	26472758	Raji	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	0.23291441745745833	[417]	[113]	2	hSpCas9	negative selection	562054
2635551	2635574	9	+	26472758	Raji	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	-1.062541466068713	[152]	[16]	-7	hSpCas9	negative selection	562055
2639933	2639956	9	+	26472758	Raji	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	-0.0957083300039121	[197]	[42]	-1	hSpCas9	negative selection	562056
2641391	2641414	9	+	26472758	Raji	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	0.11330836933070504	[242]	[60]	1	hSpCas9	negative selection	562057
2641478	2641501	9	+	26472758	K562	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-2.7555812723335533	[447]	[55]	-8	hSpCas9	negative selection	753166
2643203	2643226	9	-	26472758	K562	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	1.1014184406023497	[354]	[642]	8	hSpCas9	negative selection	753167
2643234	2643257	9	+	26472758	K562	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	1.2888128470249005	[671]	[1385]	9	hSpCas9	negative selection	753168
2643319	2643342	9	-	26472758	K562	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.893137194049876	[390]	[612]	7	hSpCas9	negative selection	753169
2643457	2643480	9	+	26472758	K562	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.6386682453380892	[1065]	[1400]	5	hSpCas9	negative selection	753170
2644832	2644855	9	+	26472758	K562	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	0.9230403356018482	[655]	[1049]	7	hSpCas9	negative selection	753171
2646542	2646565	9	-	26472758	K562	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	0.8833858834201367	[401]	[625]	7	hSpCas9	negative selection	753172
2635551	2635574	9	+	26472758	K562	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	-0.3943150294956901	[122]	[78]	-3	hSpCas9	negative selection	753173
2639933	2639956	9	+	26472758	K562	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	1.3486075779384181	[226]	[487]	9	hSpCas9	negative selection	753174
2641391	2641414	9	+	26472758	K562	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	0.7262489308713799	[458]	[640]	6	hSpCas9	negative selection	753175
2635484	2635507	9	-	26627737	DLD1	viability	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	0.25163882503516144	[697]	[433,215,144]	2	hSpCas9	negative selection	842554
2639913	2639936	9	-	26627737	DLD1	viability	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	0.0492008013102711	[649]	[241,198,191]	0	hSpCas9	negative selection	842555
2641417	2641440	9	-	26627737	DLD1	viability	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.7835139222467908	[753]	[343,481,395]	7	hSpCas9	negative selection	842556
2643234	2643257	9	+	26627737	DLD1	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.5105016889130007	[951]	[599,311,363]	5	hSpCas9	negative selection	842557
2643680	2643703	9	-	26627737	DLD1	viability	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	1.2155585512892229	[265]	[103,306,175]	9	hSpCas9	negative selection	842558
2643898	2643921	9	+	26627737	DLD1	viability	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	-0.4620976929398006	[400]	[68,49,143]	-5	hSpCas9	negative selection	842559
2635484	2635507	9	-	26627737	GBM cells	viability after 5 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	-0.0008586773756601163	[277]	[155,141]	0	hSpCas9	negative selection	924869
2639913	2639936	9	-	26627737	GBM cells	viability after 5 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	0.8716556678412617	[186]	[188,177]	9	hSpCas9	negative selection	924870
2641417	2641440	9	-	26627737	GBM cells	viability after 5 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.4968154313143398	[591]	[413,481]	7	hSpCas9	negative selection	924871
2643234	2643257	9	+	26627737	GBM cells	viability after 5 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.03677709257566231	[350]	[186,179]	0	hSpCas9	negative selection	924872
2643680	2643703	9	-	26627737	GBM cells	viability after 5 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	0.7041854824428007	[98]	[69,102]	8	hSpCas9	negative selection	924873
2643898	2643921	9	+	26627737	GBM cells	viability after 5 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.49205957985486926	[292]	[241,199]	7	hSpCas9	negative selection	924874
2635484	2635507	9	-	26627737	GBM cells	viability after 13 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	0.10510595111858115	[277]	[148,172]	1	hSpCas9	negative selection	1007184
2639913	2639936	9	-	26627737	GBM cells	viability after 13 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	0.6308425648801372	[186]	[171,144]	7	hSpCas9	negative selection	1007185
2641417	2641440	9	-	26627737	GBM cells	viability after 13 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.39415109161841944	[591]	[527,335]	5	hSpCas9	negative selection	1007186
2643234	2643257	9	+	26627737	GBM cells	viability after 13 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.1306794767185505	[350]	[170,238]	1	hSpCas9	negative selection	1007187
2643680	2643703	9	-	26627737	GBM cells	viability after 13 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	0.6157216946441509	[98]	[78,84]	7	hSpCas9	negative selection	1007188
2643898	2643921	9	+	26627737	GBM cells	viability after 13 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.2700970646444244	[292]	[226,162]	3	hSpCas9	negative selection	1007189
2635484	2635507	9	-	26627737	GBM cells	viability after 21 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	0.7843380705434029	[277]	[268,251]	7	hSpCas9	negative selection	1089499
2639913	2639936	9	-	26627737	GBM cells	viability after 21 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	0.9884521077710553	[186]	[199,202]	8	hSpCas9	negative selection	1089500
2641417	2641440	9	-	26627737	GBM cells	viability after 21 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.34143618310514867	[591]	[430,385]	3	hSpCas9	negative selection	1089501
2643234	2643257	9	+	26627737	GBM cells	viability after 21 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.02192401862457094	[350]	[190,195]	0	hSpCas9	negative selection	1089502
2643680	2643703	9	-	26627737	GBM cells	viability after 21 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	0.7002546335094233	[98]	[89,84]	7	hSpCas9	negative selection	1089503
2643898	2643921	9	+	26627737	GBM cells	viability after 21 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.961187115150534	[292]	[311,307]	8	hSpCas9	negative selection	1089504
2635484	2635507	9	-	26627737	RPE1	viability after 9 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	-1.1588014650596223	[1191]	[81,276]	-7	hSpCas9	negative selection	1171814
2639913	2639936	9	-	26627737	RPE1	viability after 9 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	-0.19607597240066102	[929]	[237,274]	-1	hSpCas9	negative selection	1171815
2641417	2641440	9	-	26627737	RPE1	viability after 9 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.8175227261548994	[1620]	[679,1170]	5	hSpCas9	negative selection	1171816
2643234	2643257	9	+	26627737	RPE1	viability after 9 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.5793124517904197	[1849]	[360,421]	-4	hSpCas9	negative selection	1171817
2643680	2643703	9	-	26627737	RPE1	viability after 9 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	0.1746002784752117	[707]	[209,301]	1	hSpCas9	negative selection	1171818
2643898	2643921	9	+	26627737	RPE1	viability after 9 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.8952586281778989	[571]	[367,287]	6	hSpCas9	negative selection	1171819
2635484	2635507	9	-	26627737	RPE1	viability after 12 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	-1.0083605831327374	[1191]	[97,223]	-6	hSpCas9	negative selection	1254129
2639913	2639936	9	-	26627737	RPE1	viability after 12 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	-0.36293948024215816	[929]	[152,237]	-2	hSpCas9	negative selection	1254130
2641417	2641440	9	-	26627737	RPE1	viability after 12 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	1.2523585221324398	[1620]	[714,1378]	7	hSpCas9	negative selection	1254131
2643234	2643257	9	+	26627737	RPE1	viability after 12 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.8473301868948016	[1849]	[284,266]	-5	hSpCas9	negative selection	1254132
2643680	2643703	9	-	26627737	RPE1	viability after 12 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	-0.5834587293448223	[707]	[90,164]	-4	hSpCas9	negative selection	1254133
2643898	2643921	9	+	26627737	RPE1	viability after 12 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	1.0414549784879317	[571]	[377,250]	6	hSpCas9	negative selection	1254134
2635484	2635507	9	-	26627737	RPE1	viability after 15 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	-0.6772489127638194	[1191]	[105,311]	-4	hSpCas9	negative selection	1336444
2639913	2639936	9	-	26627737	RPE1	viability after 15 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	-0.5004775759003878	[929]	[159,210]	-3	hSpCas9	negative selection	1336445
2641417	2641440	9	-	26627737	RPE1	viability after 15 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.789055170862978	[1620]	[491,1081]	5	hSpCas9	negative selection	1336446
2643234	2643257	9	+	26627737	RPE1	viability after 15 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.8138386917293332	[1849]	[201,389]	-5	hSpCas9	negative selection	1336447
2643680	2643703	9	-	26627737	RPE1	viability after 15 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	-0.7072217428774603	[707]	[84,158]	-4	hSpCas9	negative selection	1336448
2643898	2643921	9	+	26627737	RPE1	viability after 15 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	1.3077152551169087	[571]	[453,348]	7	hSpCas9	negative selection	1336449
2635484	2635507	9	-	26627737	RPE1	viability after 18 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	-1.5422475566422975	[1191]	[6,220]	-7	hSpCas9	negative selection	1418759
2639913	2639936	9	-	26627737	RPE1	viability after 18 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	0.5193324457670998	[929]	[205,523]	3	hSpCas9	negative selection	1418760
2641417	2641440	9	-	26627737	RPE1	viability after 18 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.7886181238086838	[1620]	[614,905]	5	hSpCas9	negative selection	1418761
2643234	2643257	9	+	26627737	RPE1	viability after 18 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.5636724533639431	[1849]	[214,468]	-4	hSpCas9	negative selection	1418762
2643680	2643703	9	-	26627737	RPE1	viability after 18 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	-1.1980456945966784	[707]	[3,167]	-6	hSpCas9	negative selection	1418763
2643898	2643921	9	+	26627737	RPE1	viability after 18 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	1.0151114803257935	[571]	[325,296]	6	hSpCas9	negative selection	1418764
2635484	2635507	9	-	26627737	HeLa	viability after 8 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	-0.877370642218504	[542]	[150,143,97]	-7	hSpCas9	negative selection	1501074
2639913	2639936	9	-	26627737	HeLa	viability after 8 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	0.25655704645541916	[326]	[165,97,239]	2	hSpCas9	negative selection	1501075
2641417	2641440	9	-	26627737	HeLa	viability after 8 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	-0.17181141955786194	[1472]	[706,559,476]	-2	hSpCas9	negative selection	1501076
2643234	2643257	9	+	26627737	HeLa	viability after 8 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.2461151711603058	[999]	[519,330,288]	-2	hSpCas9	negative selection	1501077
2643680	2643703	9	-	26627737	HeLa	viability after 8 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	-0.8044950288435236	[435]	[120,15,185]	-7	hSpCas9	negative selection	1501078
2643898	2643921	9	+	26627737	HeLa	viability after 8 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.39882269657252917	[297]	[276,84,173]	3	hSpCas9	negative selection	1501079
2635484	2635507	9	-	26627737	HeLa	viability after 12 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	-0.38941293997876036	[542]	[188,137,190]	-3	hSpCas9	negative selection	1583389
2639913	2639936	9	-	26627737	HeLa	viability after 12 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	0.9972074001316982	[326]	[376,244,192]	7	hSpCas9	negative selection	1583390
2641417	2641440	9	-	26627737	HeLa	viability after 12 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	-0.3568133319305873	[1472]	[481,458,486]	-3	hSpCas9	negative selection	1583391
2643234	2643257	9	+	26627737	HeLa	viability after 12 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.742571497474237	[999]	[246,312,173]	-6	hSpCas9	negative selection	1583392
2643680	2643703	9	-	26627737	HeLa	viability after 12 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	-0.7596337700934344	[435]	[127,29,169]	-6	hSpCas9	negative selection	1583393
2643898	2643921	9	+	26627737	HeLa	viability after 12 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.7172565320653376	[297]	[61,214,324]	6	hSpCas9	negative selection	1583394
2635484	2635507	9	-	26627737	HeLa	viability after 15 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	-1.6305680470911317	[542]	[24,6,191]	-8	hSpCas9	negative selection	1665704
2639913	2639936	9	-	26627737	HeLa	viability after 15 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	1.168855780506263	[326]	[339,141,424]	8	hSpCas9	negative selection	1665705
2641417	2641440	9	-	26627737	HeLa	viability after 15 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	-0.6320433808474653	[1472]	[396,372,390]	-5	hSpCas9	negative selection	1665706
2643234	2643257	9	+	26627737	HeLa	viability after 15 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.20783559721403067	[999]	[505,407,123]	-2	hSpCas9	negative selection	1665707
2643680	2643703	9	-	26627737	HeLa	viability after 15 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	-0.14464417918785583	[435]	[147,243,83]	-1	hSpCas9	negative selection	1665708
2643898	2643921	9	+	26627737	HeLa	viability after 15 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.21942495215733124	[297]	[122,98,206]	1	hSpCas9	negative selection	1665709
2635484	2635507	9	-	26627737	HeLa	viability after 18 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	-1.6771381658064264	[542]	[12,4,191]	-9	hSpCas9	negative selection	1748019
2639913	2639936	9	-	26627737	HeLa	viability after 18 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	1.1658971285005744	[326]	[220,124,424]	7	hSpCas9	negative selection	1748020
2641417	2641440	9	-	26627737	HeLa	viability after 18 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	-0.6119747533235724	[1472]	[271,314,390]	-5	hSpCas9	negative selection	1748021
2643234	2643257	9	+	26627737	HeLa	viability after 18 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.2264235406012962	[999]	[328,339,123]	-2	hSpCas9	negative selection	1748022
2643680	2643703	9	-	26627737	HeLa	viability after 18 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	-0.16480329130283097	[435]	[102,191,83]	-1	hSpCas9	negative selection	1748023
2643898	2643921	9	+	26627737	HeLa	viability after 18 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.163160451282228	[297]	[67,86,206]	1	hSpCas9	negative selection	1748024
2635484	2635507	9	-	26627737	HCT116	viability after 6 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	2.9658280645180186	[213]	[296,243]	9	hSpCas9	negative selection	1830334
2639913	2639936	9	-	26627737	HCT116	viability after 6 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	0.12992768256721077	[454]	[192,14]	0	hSpCas9	negative selection	1830335
2641417	2641440	9	-	26627737	HCT116	viability after 6 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	-0.25665436624108207	[1402]	[221,163]	-1	hSpCas9	negative selection	1830336
2643234	2643257	9	+	26627737	HCT116	viability after 6 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.581593236435549	[1213]	[380,232]	3	hSpCas9	negative selection	1830337
2643680	2643703	9	-	26627737	HCT116	viability after 6 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	-0.3092923050901123	[386]	[119,9]	-2	hSpCas9	negative selection	1830338
2643898	2643921	9	+	26627737	HCT116	viability after 6 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	-0.6101561917012158	[828]	[76,89]	-3	hSpCas9	negative selection	1830339
2635484	2635507	9	-	26627737	HCT116	viability after 8 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	0.14987654707197284	[224]	[161,187,63]	1	hSpCas9	negative selection	1912649
2639913	2639936	9	-	26627737	HCT116	viability after 8 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	0.30596271004068837	[220]	[142,198,109]	3	hSpCas9	negative selection	1912650
2641417	2641440	9	-	26627737	HCT116	viability after 8 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.6399647908333893	[526]	[469,364,521]	6	hSpCas9	negative selection	1912651
2643234	2643257	9	+	26627737	HCT116	viability after 8 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.8812382528652024	[343]	[352,302,390]	7	hSpCas9	negative selection	1912652
2643680	2643703	9	-	26627737	HCT116	viability after 8 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	1.0862141853249219	[129]	[124,113,215]	8	hSpCas9	negative selection	1912653
2643898	2643921	9	+	26627737	HCT116	viability after 8 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.21798044745949607	[259]	[149,132,215]	2	hSpCas9	negative selection	1912654
2635484	2635507	9	-	26627737	HCT116	viability after 9 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	1.4362891954468349	[213]	[76,215]	8	hSpCas9	negative selection	1994964
2639913	2639936	9	-	26627737	HCT116	viability after 9 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	1.4777990623582284	[454]	[286,378]	8	hSpCas9	negative selection	1994965
2641417	2641440	9	-	26627737	HCT116	viability after 9 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	-1.2028157142967306	[1402]	[312,43]	-7	hSpCas9	negative selection	1994966
2643234	2643257	9	+	26627737	HCT116	viability after 9 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.950223955796686	[1213]	[646,609]	6	hSpCas9	negative selection	1994967
2643680	2643703	9	-	26627737	HCT116	viability after 9 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	-0.7943084809499329	[386]	[115,14]	-5	hSpCas9	negative selection	1994968
2643898	2643921	9	+	26627737	HCT116	viability after 9 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	-1.080704414889115	[828]	[188,37]	-6	hSpCas9	negative selection	1994969
2635484	2635507	9	-	26627737	HCT116	viability after 12 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	0.532366777664758	[224]	[198,187,123]	5	hSpCas9	negative selection	2077279
2639913	2639936	9	-	26627737	HCT116	viability after 12 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	1.2979332781840343	[220]	[189,446,231]	8	hSpCas9	negative selection	2077280
2641417	2641440	9	-	26627737	HCT116	viability after 12 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.6851754331113341	[526]	[412,495,430]	6	hSpCas9	negative selection	2077281
2643234	2643257	9	+	26627737	HCT116	viability after 12 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.6698901527241796	[343]	[309,333,217]	6	hSpCas9	negative selection	2077282
2643680	2643703	9	-	26627737	HCT116	viability after 12 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	1.2781982007950827	[129]	[213,171,106]	8	hSpCas9	negative selection	2077283
2643898	2643921	9	+	26627737	HCT116	viability after 12 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.1655153476735859	[259]	[75,213,177]	1	hSpCas9	negative selection	2077284
2635484	2635507	9	-	26627737	HCT116	viability after 15 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	0.5478402748591695	[224]	[305,255,20]	5	hSpCas9	negative selection	2159594
2639913	2639936	9	-	26627737	HCT116	viability after 15 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	1.2279783888746514	[220]	[181,410,284]	8	hSpCas9	negative selection	2159595
2641417	2641440	9	-	26627737	HCT116	viability after 15 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.27803951430216733	[526]	[532,374,214]	2	hSpCas9	negative selection	2159596
2643234	2643257	9	+	26627737	HCT116	viability after 15 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.9581859648473151	[343]	[529,232,405]	7	hSpCas9	negative selection	2159597
2643680	2643703	9	-	26627737	HCT116	viability after 15 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	0.9532024257466013	[129]	[217,113,110]	7	hSpCas9	negative selection	2159598
2643898	2643921	9	+	26627737	HCT116	viability after 15 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.08544906128373879	[259]	[221,183,77]	0	hSpCas9	negative selection	2159599
2635484	2635507	9	-	26627737	HCT116	viability after 18 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	1.437054536664086	[224]	[569,177,135]	8	hSpCas9	negative selection	2241909
2639913	2639936	9	-	26627737	HCT116	viability after 18 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	0.7151267650205895	[220]	[93,218,211]	6	hSpCas9	negative selection	2241910
2641417	2641440	9	-	26627737	HCT116	viability after 18 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.7208170809724214	[526]	[476,453,321]	6	hSpCas9	negative selection	2241911
2643234	2643257	9	+	26627737	HCT116	viability after 18 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	1.3015236690243914	[343]	[481,369,378]	8	hSpCas9	negative selection	2241912
2643680	2643703	9	-	26627737	HCT116	viability after 18 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	1.035131797631476	[129]	[189,106,88]	7	hSpCas9	negative selection	2241913
2643898	2643921	9	+	26627737	HCT116	viability after 18 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.15390522270912732	[259]	[85,217,108]	1	hSpCas9	negative selection	2241914
2627716	2627739	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTAGCTGGGTGTGGTGGTGCGAG	VLDLR	ENSG00000147852	0.8185981808215854	[62,12]	[14,13]	3	dCas9-VP64	positive selection	2474892
2627716	2627739	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTAGCTGGGTGTGGTGGTGCGAG	VLDLR	ENSG00000147852	0.3396219715193111	[78,56]	[31,22]	2	dCas9-VP64	positive selection	2570147
2644996	2645019	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTTGTATCAACTTAAAAGGCGG	VLDLR	ENSG00000147852	0.11103866439023657	[4,4]	[4,2]	2	hSpCas9	positive selection	3031822
2643430	2643453	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGCCAGCGAAATCCAGTGCGG	VLDLR	ENSG00000147852	0.05149170964897559	[4,4]	[4,3]	1	hSpCas9	positive selection	3031823
2635512	2635535	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGTTGTGGAAATGTGATGGGG	VLDLR	ENSG00000147852	-0.4566677722919308	[4,4]	[4,0]	-6	hSpCas9	positive selection	3031824
2641479	2641502	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-0.018877728530338034	[5,4]	[4,3]	0	hSpCas9	positive selection	3031825
2644996	2645019	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTTGTATCAACTTAAAAGGCGG	VLDLR	ENSG00000147852	-0.01030198929382578	[4,4]	[4,1]	0	hSpCas9	positive selection	3099680
2643430	2643453	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGCCAGCGAAATCCAGTGCGG	VLDLR	ENSG00000147852	-0.47973668067796826	[4,4]	[4,0]	-6	hSpCas9	positive selection	3099681
2635512	2635535	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGTTGTGGAAATGTGATGGGG	VLDLR	ENSG00000147852	-0.3257490794519016	[4,4]	[4,0]	-5	hSpCas9	positive selection	3099682
2641479	2641502	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	0.04446610591708672	[5,5]	[4,2]	0	hSpCas9	positive selection	3099683
2622188	2622211		+	24336571	A375	resistance to PLX after 7 days	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.01817257525581062	[49,43]	[44,49]	0	hSpCas9	positive selection	3155014
2643829	2643852		+	24336571	A375	resistance to PLX after 7 days	CTTTGTAGTCAATCAGTGCTTGG	VLDLR	ENSG00000147852	0.08689854988375645	[58,52]	[60,57]	3	hSpCas9	positive selection	3155015
2622218	2622241		+	24336571	A375	resistance to PLX after 7 days	GGCTGCTGCTCGCGCTGTGCTGG	VLDLR	ENSG00000147852	-0.13778089198322985	[24,24]	[23,19]	-4	hSpCas9	positive selection	3155016
2643946	2643969		-	24336571	A375	resistance to PLX after 7 days	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-0.0749479768541883	[28,29]	[25,28]	-2	hSpCas9	positive selection	3155017
2622188	2622211		+	24336571	A375	resistance to PLX after 14 days	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	-0.15814642770694332	[41,44]	[20,14]	-2	hSpCas9	positive selection	3212807
2643829	2643852		+	24336571	A375	resistance to PLX after 14 days	CTTTGTAGTCAATCAGTGCTTGG	VLDLR	ENSG00000147852	-0.10971025741463603	[72,49]	[26,25]	-1	hSpCas9	positive selection	3212808
2622218	2622241		+	24336571	A375	resistance to PLX after 14 days	GGCTGCTGCTCGCGCTGTGCTGG	VLDLR	ENSG00000147852	-0.5306865224656845	[24,22]	[6,7]	-6	hSpCas9	positive selection	3212809
2643946	2643969		-	24336571	A375	resistance to PLX after 14 days	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-0.34542637511160645	[39,29]	[10,13]	-4	hSpCas9	positive selection	3212810
2622188	2622211		+	24336571	A375	viability after 7 days	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.483296170160574	[34]	[49,43]	7	hSpCas9	negative selection	3270600
2643829	2643852		+	24336571	A375	viability after 7 days	CTTTGTAGTCAATCAGTGCTTGG	VLDLR	ENSG00000147852	0.38878649569304735	[44]	[58,52]	6	hSpCas9	negative selection	3270601
2622218	2622241		+	24336571	A375	viability after 7 days	GGCTGCTGCTCGCGCTGTGCTGG	VLDLR	ENSG00000147852	0.2587767241475838	[21]	[24,24]	4	hSpCas9	negative selection	3270602
2643946	2643969		-	24336571	A375	viability after 7 days	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-0.29917780786612247	[37]	[28,29]	-4	hSpCas9	negative selection	3270603
2622188	2622211		+	24336571	A375	viability after 14 days	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.38936018599353694	[34]	[41,44]	5	hSpCas9	negative selection	3328393
2643829	2643852		+	24336571	A375	viability after 14 days	CTTTGTAGTCAATCAGTGCTTGG	VLDLR	ENSG00000147852	0.5287518509914853	[44]	[72,49]	6	hSpCas9	negative selection	3328394
2622218	2622241		+	24336571	A375	viability after 14 days	GGCTGCTGCTCGCGCTGTGCTGG	VLDLR	ENSG00000147852	0.22342791750413038	[21]	[24,22]	3	hSpCas9	negative selection	3328395
2643946	2643969		-	24336571	A375	viability after 14 days	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-0.03691867778258673	[37]	[39,29]	0	hSpCas9	negative selection	3328396
2644799	2644822	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	0.3384629741712407	[120,120]	[0,0]	1	hSpCas9	positive selection	3400916
2643946	2643969	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-2.2061981618253452	[705,705]	[0,0]	-9	hSpCas9	positive selection	3400917
2643892	2643915	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.2662357446111776	[183,183]	[0,0]	-2	hSpCas9	positive selection	3400918
2644995	2645018	9	+	26780180	HT29	viability (Avana library 4 designs)	ATTTGTATCAACTTAAAAGGCGG	VLDLR	ENSG00000147852	0.294806708307699	[]	[]	1	hSpCas9	negative selection	3471054
2643429	2643452	9	+	26780180	HT29	viability (Avana library 4 designs)	CCAGCCAGCGAAATCCAGTGCGG	VLDLR	ENSG00000147852	-0.309140573022194	[]	[]	-5	hSpCas9	negative selection	3471055
2635511	2635534	9	+	26780180	HT29	viability (Avana library 4 designs)	GCTGTTGTGGAAATGTGATGGGG	VLDLR	ENSG00000147852	-1.02798772126197	[]	[]	-9	hSpCas9	negative selection	3471056
2641478	2641501	9	+	26780180	HT29	viability (Avana library 4 designs)	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-0.143324451285312	[]	[]	-2	hSpCas9	negative selection	3471057
2641478	2641501	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-3.73082370406332	[]	[]	-4	hSpCas9	negative selection	3577670
2644995	2645018	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTTGTATCAACTTAAAAGGCGG	VLDLR	ENSG00000147852	-18.2096245341675	[]	[]	-9	hSpCas9	negative selection	3577671
2643429	2643452	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGCCAGCGAAATCCAGTGCGG	VLDLR	ENSG00000147852	5.79981362497357	[]	[]	9	hSpCas9	negative selection	3577672
2635511	2635534	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTTGTGGAAATGTGATGGGG	VLDLR	ENSG00000147852	0.174591910204649	[]	[]	0	hSpCas9	negative selection	3577673
2643457	2643480	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.224774151703974	[]	[]	0	hSpCas9	negative selection	3577674
2635473	2635496	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGTGCACTGGAATTGGGAGGG	VLDLR	ENSG00000147852	0.639269936323238	[]	[]	0	hSpCas9	negative selection	3577675
2641478	2641501	9	+	26780180	A375	viability (Avana lentiGuide)	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	4.17024659577637	[]	[]	4	hSpCas9	negative selection	3686329
2644995	2645018	9	+	26780180	A375	viability (Avana lentiGuide)	ATTTGTATCAACTTAAAAGGCGG	VLDLR	ENSG00000147852	-3.17747136622709	[]	[]	-5	hSpCas9	negative selection	3686330
2643429	2643452	9	+	26780180	A375	viability (Avana lentiGuide)	CCAGCCAGCGAAATCCAGTGCGG	VLDLR	ENSG00000147852	2.98059039800565	[]	[]	3	hSpCas9	negative selection	3686331
2635511	2635534	9	+	26780180	A375	viability (Avana lentiGuide)	GCTGTTGTGGAAATGTGATGGGG	VLDLR	ENSG00000147852	0.894507888021497	[]	[]	1	hSpCas9	negative selection	3686332
2643457	2643480	9	+	26780180	A375	viability (Avana lentiGuide)	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	-0.0961521278049175	[]	[]	0	hSpCas9	negative selection	3686333
2635473	2635496	9	-	26780180	A375	viability (Avana lentiGuide)	TTTGTGCACTGGAATTGGGAGGG	VLDLR	ENSG00000147852	0.659719170797343	[]	[]	0	hSpCas9	negative selection	3686334
2641478	2641501	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-0.374852855258902	[6]	[4,3]	-5	hSpCas9	positive selection	3794936
2644995	2645018	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTTGTATCAACTTAAAAGGCGG	VLDLR	ENSG00000147852	-0.9371895088758986	[8]	[4,3]	-8	hSpCas9	positive selection	3794937
2643429	2643452	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGCCAGCGAAATCCAGTGCGG	VLDLR	ENSG00000147852	0.1983405978325759	[5]	[6,5]	5	hSpCas9	positive selection	3794938
2635511	2635534	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTTGTGGAAATGTGATGGGG	VLDLR	ENSG00000147852	0.1104196357723676	[5]	[5,5]	3	hSpCas9	positive selection	3794939
2643457	2643480	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.10332116976600342	[5]	[6,5]	2	hSpCas9	positive selection	3794940
2635473	2635496	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGTGCACTGGAATTGGGAGGG	VLDLR	ENSG00000147852	0.05703304541864884	[6]	[6,6]	1	hSpCas9	positive selection	3794941
2641478	2641501	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	0.1872924163334243	[6]	[6,5]	4	hSpCas9	positive selection	3903543
2644995	2645018	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTTGTATCAACTTAAAAGGCGG	VLDLR	ENSG00000147852	0.16286298471651728	[5]	[5,4]	4	hSpCas9	positive selection	3903544
2643429	2643452	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGCCAGCGAAATCCAGTGCGG	VLDLR	ENSG00000147852	0.19992299774922567	[6]	[5,6]	5	hSpCas9	positive selection	3903545
2635511	2635534	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTTGTGGAAATGTGATGGGG	VLDLR	ENSG00000147852	0.20477723341021348	[5]	[5,5]	5	hSpCas9	positive selection	3903546
2643457	2643480	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.13277650267917745	[6]	[4,6]	3	hSpCas9	positive selection	3903547
2635473	2635496	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGTGCACTGGAATTGGGAGGG	VLDLR	ENSG00000147852	0.2028781597500121	[7]	[7,7]	5	hSpCas9	positive selection	3903548
2644786	2644809	9	-	26780180	A375	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.906033424045554	[]	[]	4	hSpCas9	negative selection	4011591
2622188	2622211	9	+	26780180	A375	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	1.00374796773485	[]	[]	4	hSpCas9	negative selection	4011592
2643946	2643969	9	-	26780180	A375	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.455610194613027	[]	[]	1	hSpCas9	negative selection	4011593
2644799	2644822	9	+	26780180	A375	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	1.63199579875103	[]	[]	8	hSpCas9	negative selection	4011594
2643892	2643915	9	+	26780180	A375	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	1.5117157978109	[]	[]	8	hSpCas9	negative selection	4011595
2622260	2622283	9	-	26780180	A375	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.314366211214375	[]	[]	0	hSpCas9	negative selection	4011596
2644786	2644809	9	-	26780180	HT29	viability (GeCKOv2 library)	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.378702306232165	[]	[]	1	hSpCas9	negative selection	4119557
2622188	2622211	9	+	26780180	HT29	viability (GeCKOv2 library)	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	1.52010617694194	[]	[]	7	hSpCas9	negative selection	4119558
2643946	2643969	9	-	26780180	HT29	viability (GeCKOv2 library)	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.794552898057084	[]	[]	3	hSpCas9	negative selection	4119559
2644799	2644822	9	+	26780180	HT29	viability (GeCKOv2 library)	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	1.98859716669114	[]	[]	9	hSpCas9	negative selection	4119560
2643892	2643915	9	+	26780180	HT29	viability (GeCKOv2 library)	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	1.64756276235083	[]	[]	8	hSpCas9	negative selection	4119561
2622260	2622283	9	-	26780180	HT29	viability (GeCKOv2 library)	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.33773944907016	[]	[]	0	hSpCas9	negative selection	4119562
2622188	2622211	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.14410398290517806	[5]	[3,4]	3	hSpCas9	positive selection	4181766
2643829	2643852	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTTGTAGTCAATCAGTGCTTGG	VLDLR	ENSG00000147852	0.21927695850302487	[5]	[4,4]	5	hSpCas9	positive selection	4181767
2622218	2622241	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCTGCTGCTCGCGCTGTGCTGG	VLDLR	ENSG00000147852	0.11859007752566378	[4]	[3,2]	3	hSpCas9	positive selection	4181768
2643946	2643969	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.4271725401622361	[4]	[4,3]	8	hSpCas9	positive selection	4181769
2622188	2622211	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	1.0245872482782126	[5]	[4,5,5,3]	7	hSpCas9	positive selection	4245788
2643829	2643852	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTTGTAGTCAATCAGTGCTTGG	VLDLR	ENSG00000147852	1.0759936332539835	[5]	[4,4,5,5]	7	hSpCas9	positive selection	4245789
2622218	2622241	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCTGCTGCTCGCGCTGTGCTGG	VLDLR	ENSG00000147852	0.19897921708424987	[4]	[3,0,4,0]	1	hSpCas9	positive selection	4245790
2643946	2643969	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.05410872927121929	[5]	[0,5,4,0]	0	hSpCas9	positive selection	4245791
2622188	2622211	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.20318270590887783	[2]	[2,2]	4	hSpCas9	positive selection	4307300
2622260	2622283	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.35220130547300266	[0]	[0,0]	7	hSpCas9	positive selection	4307301
2644786	2644809	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.3101377630109027	[3]	[3,3]	6	hSpCas9	positive selection	4307302
2644799	2644822	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.3793089233427433	[2]	[1,0]	-7	hSpCas9	positive selection	4371548
2643946	2643969	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.23714533920689984	[4]	[5,3]	5	hSpCas9	positive selection	4371549
2643892	2643915	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.5056750007253823	[3]	[1,0]	-8	hSpCas9	positive selection	4371550
2643331	2643353	9	-	27760321	OCIAML3	viability	TCGTCGCATACCCAGCTGATGG	VLDLR	ENSG00000147852	-0.35116640395331333	[767,693]	[429,470]	-4	hSpCas9	negative selection	4453286
2643436	2643458	9	+	27760321	OCIAML3	viability	GCGAAATCCAGTGCGGCTCTGG	VLDLR	ENSG00000147852	-0.035001238500124154	[672,579]	[406,567]	0	hSpCas9	negative selection	4453287
2643458	2643480	9	+	27760321	OCIAML3	viability	CGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.4495542904294125	[258,212]	[193,324]	5	hSpCas9	negative selection	4453288
2643628	2643650	9	-	27760321	OCIAML3	viability	TCAGGTCGGCAAGTTCGAGAGG	VLDLR	ENSG00000147852	-0.20029901963310154	[552,446]	[219,492]	-2	hSpCas9	negative selection	4453289
2643703	2643725	9	+	27760321	OCIAML3	viability	GTATCCGAGACTGTGTCGATGG	VLDLR	ENSG00000147852	0.6698634526251004	[540,450]	[591,643]	7	hSpCas9	negative selection	4453290
2643331	2643353	9	-	27760321	OCIAML2	viability	TCGTCGCATACCCAGCTGATGG	VLDLR	ENSG00000147852	0.01383756814706627	[767,693]	[539,670]	0	hSpCas9	negative selection	4536749
2643436	2643458	9	+	27760321	OCIAML2	viability	GCGAAATCCAGTGCGGCTCTGG	VLDLR	ENSG00000147852	0.28489636160278853	[672,579]	[446,837]	4	hSpCas9	negative selection	4536750
2643458	2643480	9	+	27760321	OCIAML2	viability	CGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.3009843927446394	[258,212]	[240,224]	4	hSpCas9	negative selection	4536751
2643628	2643650	9	-	27760321	OCIAML2	viability	TCAGGTCGGCAAGTTCGAGAGG	VLDLR	ENSG00000147852	0.5678587036808787	[552,446]	[569,630]	7	hSpCas9	negative selection	4536752
2643703	2643725	9	+	27760321	OCIAML2	viability	GTATCCGAGACTGTGTCGATGG	VLDLR	ENSG00000147852	0.7695574954596787	[540,450]	[634,741]	9	hSpCas9	negative selection	4536753
2643331	2643353	9	-	27760321	MV411	viability	TCGTCGCATACCCAGCTGATGG	VLDLR	ENSG00000147852	-0.5458754920321344	[767,693]	[252,445]	-4	hSpCas9	negative selection	4620212
2643436	2643458	9	+	27760321	MV411	viability	GCGAAATCCAGTGCGGCTCTGG	VLDLR	ENSG00000147852	0.5512871590498174	[672,579]	[763,363]	4	hSpCas9	negative selection	4620213
2643458	2643480	9	+	27760321	MV411	viability	CGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	1.7225977713301686	[258,212]	[696,232]	9	hSpCas9	negative selection	4620214
2643628	2643650	9	-	27760321	MV411	viability	TCAGGTCGGCAAGTTCGAGAGG	VLDLR	ENSG00000147852	0.5254430845755089	[552,446]	[170,924]	4	hSpCas9	negative selection	4620215
2643703	2643725	9	+	27760321	MV411	viability	GTATCCGAGACTGTGTCGATGG	VLDLR	ENSG00000147852	0.900966600712501	[540,450]	[666,520]	6	hSpCas9	negative selection	4620216
2643331	2643353	9	-	27760321	HL60	viability	TCGTCGCATACCCAGCTGATGG	VLDLR	ENSG00000147852	-0.1657202549247152	[767,693]	[593,465]	-2	hSpCas9	negative selection	4703675
2643436	2643458	9	+	27760321	HL60	viability	GCGAAATCCAGTGCGGCTCTGG	VLDLR	ENSG00000147852	0.007428046943095068	[672,579]	[395,636]	0	hSpCas9	negative selection	4703676
2643458	2643480	9	+	27760321	HL60	viability	CGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.7402881339488174	[258,212]	[337,301]	8	hSpCas9	negative selection	4703677
2643628	2643650	9	-	27760321	HL60	viability	TCAGGTCGGCAAGTTCGAGAGG	VLDLR	ENSG00000147852	0.051379422348128784	[552,446]	[435,404]	0	hSpCas9	negative selection	4703678
2643703	2643725	9	+	27760321	HL60	viability	GTATCCGAGACTGTGTCGATGG	VLDLR	ENSG00000147852	0.42409746683545774	[540,450]	[420,668]	5	hSpCas9	negative selection	4703679
2643331	2643353	9	-	27760321	HT1080	viability	TCGTCGCATACCCAGCTGATGG	VLDLR	ENSG00000147852	0.1576255685374507	[693,541]	[329,213]	0	hSpCas9	negative selection	4787138
2643436	2643458	9	+	27760321	HT1080	viability	GCGAAATCCAGTGCGGCTCTGG	VLDLR	ENSG00000147852	0.45914586169941596	[579,452]	[216,354]	2	hSpCas9	negative selection	4787139
2643458	2643480	9	+	27760321	HT1080	viability	CGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	1.294087728499039	[212,165]	[102,274]	7	hSpCas9	negative selection	4787140
2643628	2643650	9	-	27760321	HT1080	viability	TCAGGTCGGCAAGTTCGAGAGG	VLDLR	ENSG00000147852	0.8853490323038034	[446,348]	[300,283]	5	hSpCas9	negative selection	4787141
2643703	2643725	9	+	27760321	HT1080	viability	GTATCCGAGACTGTGTCGATGG	VLDLR	ENSG00000147852	0.37803079981832455	[450,351]	[88,337]	2	hSpCas9	negative selection	4787142
2643331	2643353	9	-	27760321	HT29	viability after 7 days	TCGTCGCATACCCAGCTGATGG	VLDLR	ENSG00000147852	0.2729923622835688	[693,541]	[1062,944,887]	4	hSpCas9	negative selection	4870601
2643436	2643458	9	+	27760321	HT29	viability after 7 days	GCGAAATCCAGTGCGGCTCTGG	VLDLR	ENSG00000147852	0.08259756230803683	[579,452]	[662,992,454]	1	hSpCas9	negative selection	4870602
2643458	2643480	9	+	27760321	HT29	viability after 7 days	CGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.24153395161319768	[212,165]	[379,279,218]	3	hSpCas9	negative selection	4870603
2643628	2643650	9	-	27760321	HT29	viability after 7 days	TCAGGTCGGCAAGTTCGAGAGG	VLDLR	ENSG00000147852	-0.15841594798856462	[446,348]	[497,439,442]	-2	hSpCas9	negative selection	4870604
2643703	2643725	9	+	27760321	HT29	viability after 7 days	GTATCCGAGACTGTGTCGATGG	VLDLR	ENSG00000147852	-0.0029995172533847925	[450,351]	[505,700,341]	0	hSpCas9	negative selection	4870605
2643331	2643353	9	-	27760321	HT29	viability after 25 days	TCGTCGCATACCCAGCTGATGG	VLDLR	ENSG00000147852	0.6418548030214473	[693,541]	[835,1281,1214]	7	hSpCas9	negative selection	4954064
2643436	2643458	9	+	27760321	HT29	viability after 25 days	GCGAAATCCAGTGCGGCTCTGG	VLDLR	ENSG00000147852	0.5680168151030447	[579,452]	[552,1140,958]	6	hSpCas9	negative selection	4954065
2643458	2643480	9	+	27760321	HT29	viability after 25 days	CGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	1.0495931738031143	[212,165]	[352,393,620]	9	hSpCas9	negative selection	4954066
2643628	2643650	9	-	27760321	HT29	viability after 25 days	TCAGGTCGGCAAGTTCGAGAGG	VLDLR	ENSG00000147852	0.7908134313911966	[446,348]	[867,625,868]	8	hSpCas9	negative selection	4954067
2643703	2643725	9	+	27760321	HT29	viability after 25 days	GTATCCGAGACTGTGTCGATGG	VLDLR	ENSG00000147852	0.6268133850608998	[450,351]	[419,1019,701]	7	hSpCas9	negative selection	4954068
2643331	2643353	9	-	27760321	HT29	viability after 22 days	TCGTCGCATACCCAGCTGATGG	VLDLR	ENSG00000147852	0.5497590366685106	[693,541]	[740,1128,1277]	6	hSpCas9	negative selection	5037527
2643436	2643458	9	+	27760321	HT29	viability after 22 days	GCGAAATCCAGTGCGGCTCTGG	VLDLR	ENSG00000147852	0.2395616360026268	[579,452]	[434,901,785]	2	hSpCas9	negative selection	5037528
2643458	2643480	9	+	27760321	HT29	viability after 22 days	CGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.9342639645029607	[212,165]	[478,368,405]	9	hSpCas9	negative selection	5037529
2643628	2643650	9	-	27760321	HT29	viability after 22 days	TCAGGTCGGCAAGTTCGAGAGG	VLDLR	ENSG00000147852	0.5873316558891899	[446,348]	[667,666,739]	6	hSpCas9	negative selection	5037530
2643703	2643725	9	+	27760321	HT29	viability after 22 days	GTATCCGAGACTGTGTCGATGG	VLDLR	ENSG00000147852	0.15969679061639083	[450,351]	[475,622,456]	1	hSpCas9	negative selection	5037531
2643331	2643353	9	-	27760321	HT29	viability after 19 days	TCGTCGCATACCCAGCTGATGG	VLDLR	ENSG00000147852	0.5041338860016931	[693,541]	[1139,982,901]	5	hSpCas9	negative selection	5120990
2643436	2643458	9	+	27760321	HT29	viability after 19 days	GCGAAATCCAGTGCGGCTCTGG	VLDLR	ENSG00000147852	-0.02280553209623104	[579,452]	[693,860,214]	0	hSpCas9	negative selection	5120991
2643458	2643480	9	+	27760321	HT29	viability after 19 days	CGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.7863691437893113	[212,165]	[423,159,535]	7	hSpCas9	negative selection	5120992
2643628	2643650	9	-	27760321	HT29	viability after 19 days	TCAGGTCGGCAAGTTCGAGAGG	VLDLR	ENSG00000147852	0.28665344460282716	[446,348]	[579,640,450]	2	hSpCas9	negative selection	5120993
2643703	2643725	9	+	27760321	HT29	viability after 19 days	GTATCCGAGACTGTGTCGATGG	VLDLR	ENSG00000147852	0.6059649369579554	[450,351]	[554,877,649]	6	hSpCas9	negative selection	5120994
2643331	2643353	9	-	27760321	HT29	viability after 16 days	TCGTCGCATACCCAGCTGATGG	VLDLR	ENSG00000147852	0.29909085948468284	[693,541]	[819,933,792]	3	hSpCas9	negative selection	5204453
2643436	2643458	9	+	27760321	HT29	viability after 16 days	GCGAAATCCAGTGCGGCTCTGG	VLDLR	ENSG00000147852	0.5584412382610688	[579,452]	[736,667,1141]	6	hSpCas9	negative selection	5204454
2643458	2643480	9	+	27760321	HT29	viability after 16 days	CGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.8328110473239818	[212,165]	[356,483,286]	8	hSpCas9	negative selection	5204455
2643628	2643650	9	-	27760321	HT29	viability after 16 days	TCAGGTCGGCAAGTTCGAGAGG	VLDLR	ENSG00000147852	0.8628151294934396	[446,348]	[759,946,713]	8	hSpCas9	negative selection	5204456
2643703	2643725	9	+	27760321	HT29	viability after 16 days	GTATCCGAGACTGTGTCGATGG	VLDLR	ENSG00000147852	0.49466001866624565	[450,351]	[702,834,361]	5	hSpCas9	negative selection	5204457
2643331	2643353	9	-	27760321	HT29	viability after 13 days	TCGTCGCATACCCAGCTGATGG	VLDLR	ENSG00000147852	0.3060796962947552	[693,541]	[811,972,874]	4	hSpCas9	negative selection	5287916
2643436	2643458	9	+	27760321	HT29	viability after 13 days	GCGAAATCCAGTGCGGCTCTGG	VLDLR	ENSG00000147852	0.47205693693063033	[579,452]	[691,1026,777]	6	hSpCas9	negative selection	5287917
2643458	2643480	9	+	27760321	HT29	viability after 13 days	CGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.78019279509771	[212,165]	[373,389,368]	8	hSpCas9	negative selection	5287918
2643628	2643650	9	-	27760321	HT29	viability after 13 days	TCAGGTCGGCAAGTTCGAGAGG	VLDLR	ENSG00000147852	0.2565210493212715	[446,348]	[546,595,513]	3	hSpCas9	negative selection	5287919
2643703	2643725	9	+	27760321	HT29	viability after 13 days	GTATCCGAGACTGTGTCGATGG	VLDLR	ENSG00000147852	0.10221584210330356	[450,351]	[460,556,482]	1	hSpCas9	negative selection	5287920
2643331	2643353	9	-	27760321	HT29	viability after 10 days	TCGTCGCATACCCAGCTGATGG	VLDLR	ENSG00000147852	0.4349741744966136	[693,541]	[1155,965,1005]	6	hSpCas9	negative selection	5371379
2643436	2643458	9	+	27760321	HT29	viability after 10 days	GCGAAATCCAGTGCGGCTCTGG	VLDLR	ENSG00000147852	0.1520284434267356	[579,452]	[601,955,600]	2	hSpCas9	negative selection	5371380
2643458	2643480	9	+	27760321	HT29	viability after 10 days	CGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.5302972881771034	[212,165]	[476,401,151]	7	hSpCas9	negative selection	5371381
2643628	2643650	9	-	27760321	HT29	viability after 10 days	TCAGGTCGGCAAGTTCGAGAGG	VLDLR	ENSG00000147852	0.1520613368877711	[446,348]	[472,598,584]	2	hSpCas9	negative selection	5371382
2643703	2643725	9	+	27760321	HT29	viability after 10 days	GTATCCGAGACTGTGTCGATGG	VLDLR	ENSG00000147852	0.3730048491208674	[450,351]	[655,555,730]	5	hSpCas9	negative selection	5371383
2643331	2643353	9	-	27760321	MOLM13	viability	TCGTCGCATACCCAGCTGATGG	VLDLR	ENSG00000147852	0.6159357573972671	[767,693]	[516,728]	4	hSpCas9	negative selection	5454842
2643436	2643458	9	+	27760321	MOLM13	viability	GCGAAATCCAGTGCGGCTCTGG	VLDLR	ENSG00000147852	0.35394779547867616	[672,579]	[712,226]	2	hSpCas9	negative selection	5454843
2643458	2643480	9	+	27760321	MOLM13	viability	CGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	-0.5551800742076954	[258,212]	[53,120]	-4	hSpCas9	negative selection	5454844
2643628	2643650	9	-	27760321	MOLM13	viability	TCAGGTCGGCAAGTTCGAGAGG	VLDLR	ENSG00000147852	0.4166096111507543	[552,446]	[508,259]	3	hSpCas9	negative selection	5454845
2643703	2643725	9	+	27760321	MOLM13	viability	GTATCCGAGACTGTGTCGATGG	VLDLR	ENSG00000147852	0.11652869764249868	[540,450]	[239,354]	0	hSpCas9	negative selection	5454846
2622250	2622273	9	+	27661255	K562	viability	GAGAGCGGCGCCACCGGAACCGG	VLDLR	ENSG00000147852	0.11209112501556862	[1427,1461]	[1503,1027]	4	dCas9-KRAB	negative selection	5522203
2621821	2621844	9	-	27661255	K562	viability	GAACGGAGAGGAGCCGGTAGCGG	VLDLR	ENSG00000147852	0.0686116563649799	[3500,3592]	[3193,2778]	2	dCas9-KRAB	negative selection	5522204
2621833	2621856	9	-	27661255	K562	viability	GAAGAGAGCACAGAACGGAGAGG	VLDLR	ENSG00000147852	0.2223383780754783	[1132,1241]	[1154,1061]	7	dCas9-KRAB	negative selection	5522205
2622188	2622211	9	+	27260156	BXPC3	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.0970965757072475	[405]	[353,418,417,659]	2	hSpCas9	negative selection	5579760
2622260	2622283	9	-	27260156	BXPC3	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.1131305408923966	[21]	[29,11,21,36]	2	hSpCas9	negative selection	5579761
2644786	2644809	9	-	27260156	BXPC3	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.0918189526030746	[719]	[617,830,849,940]	2	hSpCas9	negative selection	5579762
2644799	2644822	9	+	27260156	BXPC3	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.6974551474451458	[359]	[198,188,301,245]	-8	hSpCas9	negative selection	5644008
2643946	2643969	9	-	27260156	BXPC3	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.004725256348180551	[1993]	[2051,1767,2366,2207]	0	hSpCas9	negative selection	5644009
2643892	2643915	9	+	27260156	BXPC3	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	0.02709139702511261	[485]	[513,452,488,628]	0	hSpCas9	negative selection	5644010
2622188	2622211	9	+	27260156	A673	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.4254813151607726	[405]	[782,505,617,733]	8	hSpCas9	negative selection	5701011
2622260	2622283	9	-	27260156	A673	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.44344670420754984	[21]	[18,49,25,46]	8	hSpCas9	negative selection	5701012
2644786	2644809	9	-	27260156	A673	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.07850865571112642	[719]	[930,882,887,952]	2	hSpCas9	negative selection	5701013
2644799	2644822	9	+	27260156	A673	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.5299408515622284	[359]	[352,295,292,258]	-8	hSpCas9	negative selection	5765259
2643946	2643969	9	-	27260156	A673	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-0.07421169904414704	[1993]	[2582,2067,2148,2337]	-2	hSpCas9	negative selection	5765260
2643892	2643915	9	+	27260156	A673	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.041298849430234756	[485]	[596,528,498,651]	-1	hSpCas9	negative selection	5765261
2622188	2622211	9	+	27260156	A375	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.3856278185223156	[405]	[843,605,623,424]	5	hSpCas9	negative selection	5822262
2622260	2622283	9	-	27260156	A375	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.31386625321349904	[21]	[30,4,56,30]	4	hSpCas9	negative selection	5822263
2644786	2644809	9	-	27260156	A375	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.0037698006193730427	[719]	[706,933,1081,677]	0	hSpCas9	negative selection	5822264
2644799	2644822	9	+	27260156	A375	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.5801540413094051	[359]	[210,282,480,162]	-7	hSpCas9	negative selection	5886510
2643946	2643969	9	-	27260156	A375	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.250286342157402	[1993]	[3210,3500,2147,2363]	3	hSpCas9	negative selection	5886511
2643892	2643915	9	+	27260156	A375	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.39047131405856383	[485]	[472,406,384,458]	-5	hSpCas9	negative selection	5886512
2622188	2622211	9	+	27260156	COLO741	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	-0.03078614081576564	[405]	[538,563,427]	0	hSpCas9	negative selection	5943513
2622260	2622283	9	-	27260156	COLO741	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	1.1853020709363364	[21]	[60,74,55]	9	hSpCas9	negative selection	5943514
2644786	2644809	9	-	27260156	COLO741	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	-0.18176689734938828	[719]	[768,1044,627]	-4	hSpCas9	negative selection	5943515
2644799	2644822	9	+	27260156	COLO741	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.7349203429127871	[359]	[231,262,325]	-9	hSpCas9	negative selection	6007761
2643946	2643969	9	-	27260156	COLO741	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.03632366285631505	[1993]	[2486,2751,2584]	0	hSpCas9	negative selection	6007762
2643892	2643915	9	+	27260156	COLO741	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.12191854355106015	[485]	[832,490,419]	-3	hSpCas9	negative selection	6007763
2622188	2622211	9	+	27260156	CAL120	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	-0.03003405135583312	[405]	[520,350,613]	0	hSpCas9	negative selection	6064764
2622260	2622283	9	-	27260156	CAL120	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	-0.807174176312567	[21]	[34,7,6]	-8	hSpCas9	negative selection	6064765
2644786	2644809	9	-	27260156	CAL120	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	-0.14072655811956297	[719]	[872,715,856]	-2	hSpCas9	negative selection	6064766
2644799	2644822	9	+	27260156	CAL120	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.07434302019723382	[359]	[243,525,477]	-1	hSpCas9	negative selection	6129012
2643946	2643969	9	-	27260156	CAL120	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.21194092710105572	[1993]	[3660,2197,2879]	3	hSpCas9	negative selection	6129013
2643892	2643915	9	+	27260156	CAL120	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.31077878216385263	[485]	[411,375,659]	-4	hSpCas9	negative selection	6129014
2622188	2622211	9	+	27260156	CADOES1	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.283339528248048	[405]	[429,453,398,558]	5	hSpCas9	negative selection	6186015
2622260	2622283	9	-	27260156	CADOES1	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.966325983822105	[21]	[46,59,36,14]	9	hSpCas9	negative selection	6186016
2644786	2644809	9	-	27260156	CADOES1	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.037416236090534016	[719]	[542,906,657,639]	0	hSpCas9	negative selection	6186017
2644799	2644822	9	+	27260156	CADOES1	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.2784693958690557	[359]	[325,334,248,190]	-5	hSpCas9	negative selection	6250263
2643946	2643969	9	-	27260156	CADOES1	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.07986244475650528	[1993]	[1685,2062,1806,2297]	1	hSpCas9	negative selection	6250264
2643892	2643915	9	+	27260156	CADOES1	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.004532690872865258	[485]	[296,480,364,667]	0	hSpCas9	negative selection	6250265
2622188	2622211	9	+	27260156	EWS502	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.035089934461967814	[405]	[452,533,403,357]	0	hSpCas9	negative selection	6307266
2622260	2622283	9	-	27260156	EWS502	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.10342333515794166	[21]	[48,12,0,34]	1	hSpCas9	negative selection	6307267
2644786	2644809	9	-	27260156	EWS502	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.04051757391126143	[719]	[665,741,876,872]	0	hSpCas9	negative selection	6307268
2644799	2644822	9	+	27260156	EWS502	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.2603817889707103	[359]	[340,249,391,287]	-4	hSpCas9	negative selection	6371514
2643946	2643969	9	-	27260156	EWS502	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-0.1447237986155252	[1993]	[1741,1764,1834,2348]	-3	hSpCas9	negative selection	6371515
2643892	2643915	9	+	27260156	EWS502	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.2303254061488347	[485]	[336,452,419,563]	-4	hSpCas9	negative selection	6371516
2622188	2622211	9	+	27260156	EW8	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.10945782259260065	[405]	[304,483,361,261]	2	hSpCas9	negative selection	6428517
2622260	2622283	9	-	27260156	EW8	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	-0.10856996116829798	[21]	[10,29,7,17]	-2	hSpCas9	negative selection	6428518
2644786	2644809	9	-	27260156	EW8	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.21149489600871663	[719]	[784,871,533,546]	4	hSpCas9	negative selection	6428519
2644799	2644822	9	+	27260156	EW8	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.44577078497861	[359]	[119,247,200,278]	-7	hSpCas9	negative selection	6492765
2643946	2643969	9	-	27260156	EW8	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.04313657393679193	[1993]	[1768,1651,1393,1896]	0	hSpCas9	negative selection	6492766
2643892	2643915	9	+	27260156	EW8	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.057684325013592615	[485]	[244,451,396,400]	-1	hSpCas9	negative selection	6492767
2622188	2622211	9	+	27260156	CORL105	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.2742601087237368	[405]	[576,395,712,637]	5	hSpCas9	negative selection	6549768
2622260	2622283	9	-	27260156	CORL105	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.5958420320521589	[21]	[44,49,52,9]	9	hSpCas9	negative selection	6549769
2644786	2644809	9	-	27260156	CORL105	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.09610800600667557	[719]	[1028,824,890,862]	1	hSpCas9	negative selection	6549770
2644799	2644822	9	+	27260156	CORL105	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.0906902583630238	[359]	[391,329,346,506]	-2	hSpCas9	negative selection	6614016
2643946	2643969	9	-	27260156	CORL105	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.04444281852577481	[1993]	[2378,2224,2773,2310]	0	hSpCas9	negative selection	6614017
2643892	2643915	9	+	27260156	CORL105	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	0.010511435355402679	[485]	[688,629,567,407]	0	hSpCas9	negative selection	6614018
2622188	2622211	9	+	27260156	HS294T	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.4629535530844421	[405]	[203,126,326,209]	6	hSpCas9	negative selection	6671019
2622260	2622283	9	-	27260156	HS294T	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	1.663194718424732	[21]	[6,49,33,15]	9	hSpCas9	negative selection	6671020
2644786	2644809	9	-	27260156	HS294T	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.4145001987479713	[719]	[254,271,442,558]	5	hSpCas9	negative selection	6671021
2644799	2644822	9	+	27260156	HS294T	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.7132819592284687	[359]	[62,78,97,104]	-7	hSpCas9	negative selection	6735267
2643946	2643969	9	-	27260156	HS294T	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.1337426198263545	[1993]	[834,977,873,658]	1	hSpCas9	negative selection	6735268
2643892	2643915	9	+	27260156	HS294T	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.4556695289426504	[485]	[104,114,101,247]	-6	hSpCas9	negative selection	6735269
2622188	2622211	9	+	27260156	HCC44	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.26219045085529213	[405]	[743,302,841,416]	4	hSpCas9	negative selection	6792270
2622260	2622283	9	-	27260156	HCC44	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.8054121049295433	[21]	[60,3,18,90]	9	hSpCas9	negative selection	6792271
2644786	2644809	9	-	27260156	HCC44	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.08304183011180688	[719]	[811,801,1049,816]	1	hSpCas9	negative selection	6792272
2644799	2644822	9	+	27260156	HCC44	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.5211509179910787	[359]	[419,282,257,182]	-7	hSpCas9	negative selection	6856518
2643946	2643969	9	-	27260156	HCC44	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.17714450810064575	[1993]	[2515,2409,2571,2695]	3	hSpCas9	negative selection	6856519
2643892	2643915	9	+	27260156	HCC44	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.2881406660735046	[485]	[648,292,461,435]	-4	hSpCas9	negative selection	6856520
2622188	2622211	9	+	27260156	G402	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.41849553772725323	[405]	[543,792,775,529]	5	hSpCas9	negative selection	6913521
2622260	2622283	9	-	27260156	G402	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	-0.690254908539103	[21]	[0,0,37,22]	-7	hSpCas9	negative selection	6913522
2644786	2644809	9	-	27260156	G402	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.18637905166341084	[719]	[1260,1466,420,914]	2	hSpCas9	negative selection	6913523
2644799	2644822	9	+	27260156	G402	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.4523277050426705	[359]	[383,438,135,338]	-5	hSpCas9	negative selection	6977769
2643946	2643969	9	-	27260156	G402	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.46108677461908165	[1993]	[3846,3295,3552,2784]	6	hSpCas9	negative selection	6977770
2643892	2643915	9	+	27260156	G402	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.3464339417873726	[485]	[474,465,603,326]	-4	hSpCas9	negative selection	6977771
2622188	2622211	9	+	27260156	L33	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.23798652779388513	[405]	[527,190,246,525]	5	hSpCas9	negative selection	7034772
2622260	2622283	9	-	27260156	L33	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	1.4380401498572697	[21]	[59,27,33,55]	9	hSpCas9	negative selection	7034773
2644786	2644809	9	-	27260156	L33	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.1730742779083495	[719]	[796,389,506,692]	4	hSpCas9	negative selection	7034774
2644799	2644822	9	+	27260156	L33	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.719224684762076	[359]	[244,49,214,165]	-9	hSpCas9	negative selection	7099020
2643946	2643969	9	-	27260156	L33	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-0.33156787305135293	[1993]	[1573,632,1008,1613]	-7	hSpCas9	negative selection	7099021
2643892	2643915	9	+	27260156	L33	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.21215234581984255	[485]	[426,185,239,414]	-5	hSpCas9	negative selection	7099022
2622188	2622211	9	+	27260156	K562	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.2785405727592781	[405]	[568,307,329,531]	3	hSpCas9	negative selection	7156023
2622260	2622283	9	-	27260156	K562	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	-1.3929016925087012	[21]	[10,0,3,12]	-8	hSpCas9	negative selection	7156024
2644786	2644809	9	-	27260156	K562	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.26183820541727976	[719]	[864,733,885,601]	3	hSpCas9	negative selection	7156025
2644799	2644822	9	+	27260156	K562	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	0.5006904292144219	[359]	[389,539,784,128]	6	hSpCas9	negative selection	7220271
2643946	2643969	9	-	27260156	K562	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.28033552911475734	[1993]	[2034,2436,2265,1885]	3	hSpCas9	negative selection	7220272
2643892	2643915	9	+	27260156	K562	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	0.1343182603013725	[485]	[993,455,243,263]	1	hSpCas9	negative selection	7220273
2622188	2622211	9	+	27260156	HT29	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.030170743972986858	[405]	[552,490,548,430]	0	hSpCas9	negative selection	7277274
2622260	2622283	9	-	27260156	HT29	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.9828893434393651	[21]	[70,50,25,62]	9	hSpCas9	negative selection	7277275
2644786	2644809	9	-	27260156	HT29	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.14278434669994733	[719]	[1190,1054,912,750]	2	hSpCas9	negative selection	7277276
2644799	2644822	9	+	27260156	HT29	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.45330606672096985	[359]	[446,257,294,284]	-7	hSpCas9	negative selection	7341522
2643946	2643969	9	-	27260156	HT29	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.009836027885790077	[1993]	[2717,2324,2436,2293]	0	hSpCas9	negative selection	7341523
2643892	2643915	9	+	27260156	HT29	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.2069764447245324	[485]	[606,618,482,368]	-4	hSpCas9	negative selection	7341524
2622188	2622211	9	+	27260156	MHHES1	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.22249451540458726	[405]	[466,488,515,616]	4	hSpCas9	negative selection	7398525
2622260	2622283	9	-	27260156	MHHES1	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.8163349975064942	[21]	[84,31,35,27]	9	hSpCas9	negative selection	7398526
2644786	2644809	9	-	27260156	MHHES1	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.07237431903722913	[719]	[785,1162,795,703]	1	hSpCas9	negative selection	7398527
2644799	2644822	9	+	27260156	MHHES1	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.5669444250462191	[359]	[316,303,341,160]	-8	hSpCas9	negative selection	7462773
2643946	2643969	9	-	27260156	MHHES1	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.21204193634221014	[1993]	[2496,2664,3352,1976]	4	hSpCas9	negative selection	7462774
2643892	2643915	9	+	27260156	MHHES1	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.008450518478265473	[485]	[614,586,560,438]	0	hSpCas9	negative selection	7462775
2622188	2622211	9	+	27260156	MEWO	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.2493066005185051	[405]	[606,347,429]	5	hSpCas9	negative selection	7519776
2622260	2622283	9	-	27260156	MEWO	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.572357951235845	[21]	[51,20,22]	9	hSpCas9	negative selection	7519777
2644786	2644809	9	-	27260156	MEWO	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	1.0489039240025158	[719]	[790,759,2515]	9	hSpCas9	negative selection	7519778
2644799	2644822	9	+	27260156	MEWO	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.9932895164849689	[359]	[149,128,224]	-9	hSpCas9	negative selection	7584024
2643946	2643969	9	-	27260156	MEWO	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.020861589343702303	[1993]	[2055,1536,2117]	0	hSpCas9	negative selection	7584025
2643892	2643915	9	+	27260156	MEWO	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.034954847682399336	[485]	[566,477,309]	0	hSpCas9	negative selection	7584026
2622188	2622211	9	+	27260156	LNCAPCLONEFGC	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.3338691979746917	[405]	[490,463,528,378]	5	hSpCas9	negative selection	7641027
2622260	2622283	9	-	27260156	LNCAPCLONEFGC	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.5295202291570225	[21]	[12,22,70,14]	8	hSpCas9	negative selection	7641028
2644786	2644809	9	-	27260156	LNCAPCLONEFGC	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	-0.07486676446241491	[719]	[666,455,737,642]	-1	hSpCas9	negative selection	7641029
2644799	2644822	9	+	27260156	LNCAPCLONEFGC	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.29677437415108743	[359]	[230,375,237,205]	-5	hSpCas9	negative selection	7705275
2643946	2643969	9	-	27260156	LNCAPCLONEFGC	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.21985774149431503	[1993]	[1840,1873,2754,2059]	3	hSpCas9	negative selection	7705276
2643892	2643915	9	+	27260156	LNCAPCLONEFGC	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.12186247584009789	[485]	[371,400,404,440]	-2	hSpCas9	negative selection	7705277
2622188	2622211	9	+	27260156	PANC0327	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.05591336094102989	[405]	[318,349,338,489]	0	hSpCas9	negative selection	7762278
2622260	2622283	9	-	27260156	PANC0327	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	-0.6160449240438739	[21]	[41,7,1,1]	-7	hSpCas9	negative selection	7762279
2644786	2644809	9	-	27260156	PANC0327	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	-0.26140599911340007	[719]	[634,458,475,581]	-4	hSpCas9	negative selection	7762280
2644799	2644822	9	+	27260156	PANC0327	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.5648987341585815	[359]	[441,124,211,115]	-7	hSpCas9	negative selection	7826526
2643946	2643969	9	-	27260156	PANC0327	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.013222073716044669	[1993]	[1981,1361,1567,2307]	0	hSpCas9	negative selection	7826527
2643892	2643915	9	+	27260156	PANC0327	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.3083371537357221	[485]	[248,413,412,301]	-4	hSpCas9	negative selection	7826528
2622188	2622211	9	+	27260156	NCIH2009	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.32184838811215166	[405]	[557,708,828]	4	hSpCas9	negative selection	7883529
2622260	2622283	9	-	27260156	NCIH2009	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.5898869281917909	[21]	[19,74,37]	7	hSpCas9	negative selection	7883530
2644786	2644809	9	-	27260156	NCIH2009	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.28357775274442887	[719]	[1364,1117,1217]	4	hSpCas9	negative selection	7883531
2644799	2644822	9	+	27260156	NCIH2009	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.23947110885890388	[359]	[757,372,212]	-3	hSpCas9	negative selection	7947777
2643946	2643969	9	-	27260156	NCIH2009	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-0.13718607046689568	[1993]	[2761,2344,2536]	-2	hSpCas9	negative selection	7947778
2643892	2643915	9	+	27260156	NCIH2009	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.11271126214306303	[485]	[777,437,699]	-1	hSpCas9	negative selection	7947779
2622188	2622211	9	+	27260156	NCIH1373	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.36386308437396053	[405]	[912,332,571,157]	3	hSpCas9	negative selection	8004780
2622260	2622283	9	-	27260156	NCIH1373	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.5523705891904065	[21]	[6,6,61,17]	5	hSpCas9	negative selection	8004781
2644786	2644809	9	-	27260156	NCIH1373	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	-0.12946402710540045	[719]	[803,544,670,255]	-1	hSpCas9	negative selection	8004782
2644799	2644822	9	+	27260156	NCIH1373	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	0.19287530014588666	[359]	[701,272,527,102]	2	hSpCas9	negative selection	8069028
2643946	2643969	9	-	27260156	NCIH1373	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.597075641178622	[1993]	[3597,3727,3566,670]	6	hSpCas9	negative selection	8069029
2643892	2643915	9	+	27260156	NCIH1373	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.13160147665409086	[485]	[756,236,396,177]	-1	hSpCas9	negative selection	8069030
2622188	2622211	9	+	27260156	PATU8902	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.6499099464576525	[405]	[676,777,1257,713]	6	hSpCas9	negative selection	8126031
2622260	2622283	9	-	27260156	PATU8902	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	-0.6259698246194398	[21]	[0,56,3,21]	-6	hSpCas9	negative selection	8126032
2644786	2644809	9	-	27260156	PATU8902	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.04909807924674281	[719]	[1527,949,672,1083]	0	hSpCas9	negative selection	8126033
2644799	2644822	9	+	27260156	PATU8902	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.1551446242558675	[359]	[382,562,373,504]	-1	hSpCas9	negative selection	8190279
2643946	2643969	9	-	27260156	PATU8902	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.6495071285993768	[1993]	[5135,4786,2537,5532]	6	hSpCas9	negative selection	8190280
2643892	2643915	9	+	27260156	PATU8902	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.5108010530976332	[485]	[234,629,408,665]	-5	hSpCas9	negative selection	8190281
2622188	2622211	9	+	27260156	PANC1	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.12211734672241079	[405]	[547,379,287,303]	2	hSpCas9	negative selection	8247282
2622260	2622283	9	-	27260156	PANC1	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	-0.9835277830026143	[21]	[3,4,9,16]	-8	hSpCas9	negative selection	8247283
2644786	2644809	9	-	27260156	PANC1	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.03992181429396202	[719]	[583,1074,635,372]	0	hSpCas9	negative selection	8247284
2644799	2644822	9	+	27260156	PANC1	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.44776220255290633	[359]	[225,303,165,222]	-6	hSpCas9	negative selection	8311530
2643946	2643969	9	-	27260156	PANC1	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-0.03359281053737506	[1993]	[1304,2343,1690,1499]	0	hSpCas9	negative selection	8311531
2643892	2643915	9	+	27260156	PANC1	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	0.3502407818818485	[485]	[460,956,479,341]	5	hSpCas9	negative selection	8311532
2622188	2622211	9	+	27260156	PANC0813	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.17995459400296795	[405]	[564,619,575,408]	3	hSpCas9	negative selection	8368533
2622260	2622283	9	-	27260156	PANC0813	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	-0.04280547229540499	[21]	[38,7,35,18]	0	hSpCas9	negative selection	8368534
2644786	2644809	9	-	27260156	PANC0813	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	-0.07011872772325689	[719]	[938,851,796,653]	-1	hSpCas9	negative selection	8368535
2644799	2644822	9	+	27260156	PANC0813	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.21104486772092534	[359]	[288,373,306,476]	-3	hSpCas9	negative selection	8432781
2643946	2643969	9	-	27260156	PANC0813	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.1022034711945099	[1993]	[2401,2875,2202,2556]	1	hSpCas9	negative selection	8432782
2643892	2643915	9	+	27260156	PANC0813	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.21438282018662147	[485]	[465,458,440,592]	-3	hSpCas9	negative selection	8432783
2622188	2622211	9	+	27260156	RDES	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.35576444116002065	[405]	[478,672,583,662]	6	hSpCas9	negative selection	8489784
2622260	2622283	9	-	27260156	RDES	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.7264445042171164	[21]	[21,82,22,36]	9	hSpCas9	negative selection	8489785
2644786	2644809	9	-	27260156	RDES	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.34780307339970973	[719]	[988,988,1082,1155]	5	hSpCas9	negative selection	8489786
2644799	2644822	9	+	27260156	RDES	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.1656374267333891	[359]	[283,340,354,530]	-3	hSpCas9	negative selection	8554032
2643946	2643969	9	-	27260156	RDES	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.1733201865365417	[1993]	[2138,2547,2869,2858]	3	hSpCas9	negative selection	8554033
2643892	2643915	9	+	27260156	RDES	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	0.007077916353864677	[485]	[450,506,694,619]	0	hSpCas9	negative selection	8554034
2622188	2622211	9	+	27260156	PC3	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.10376903938136671	[405]	[209,518,650,505]	2	hSpCas9	negative selection	8611035
2622260	2622283	9	-	27260156	PC3	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.41452971075689327	[21]	[10,36,77,14]	8	hSpCas9	negative selection	8611036
2644786	2644809	9	-	27260156	PC3	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.026044977291832305	[719]	[321,797,1176,930]	0	hSpCas9	negative selection	8611037
2644799	2644822	9	+	27260156	PC3	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.9915059983909167	[359]	[161,166,210,177]	-9	hSpCas9	negative selection	8675283
2643946	2643969	9	-	27260156	PC3	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-0.09790878166583195	[1993]	[1203,1468,3525,2011]	-2	hSpCas9	negative selection	8675284
2643892	2643915	9	+	27260156	PC3	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.061891380409791884	[485]	[335,469,742,417]	-1	hSpCas9	negative selection	8675285
2622188	2622211	9	+	27260156	PATU8988T	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.3335804561406292	[405]	[408,403,606,551]	6	hSpCas9	negative selection	8732286
2622260	2622283	9	-	27260156	PATU8988T	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	-0.4478646203128296	[21]	[25,2,17,13]	-6	hSpCas9	negative selection	8732287
2644786	2644809	9	-	27260156	PATU8988T	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.025108262883964838	[719]	[655,1081,547,571]	0	hSpCas9	negative selection	8732288
2644799	2644822	9	+	27260156	PATU8988T	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.9284909216914154	[359]	[164,226,106,241]	-8	hSpCas9	negative selection	8796534
2643946	2643969	9	-	27260156	PATU8988T	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.057234310715234216	[1993]	[1540,2899,1937,1699]	1	hSpCas9	negative selection	8796535
2643892	2643915	9	+	27260156	PATU8988T	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.14662977796198964	[485]	[450,442,392,410]	-3	hSpCas9	negative selection	8796536
2622188	2622211	9	+	27260156	T47D	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.08837336511730333	[405]	[618,426,467,504]	1	hSpCas9	negative selection	8853537
2622260	2622283	9	-	27260156	T47D	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.8768969123432631	[21]	[39,31,32,85]	9	hSpCas9	negative selection	8853538
2644786	2644809	9	-	27260156	T47D	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.2339158198220247	[719]	[1040,1012,875,1015]	5	hSpCas9	negative selection	8853539
2644799	2644822	9	+	27260156	T47D	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.4200712551923267	[359]	[347,309,315,278]	-7	hSpCas9	negative selection	8917785
2643946	2643969	9	-	27260156	T47D	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.01326299378350937	[1993]	[2531,2177,2364,2315]	0	hSpCas9	negative selection	8917786
2643892	2643915	9	+	27260156	T47D	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.026369414605373485	[485]	[596,406,609,623]	0	hSpCas9	negative selection	8917787
2622188	2622211	9	+	27260156	SU8686	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.35741984523718134	[405]	[376,408,666,663]	6	hSpCas9	negative selection	8974788
2622260	2622283	9	-	27260156	SU8686	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.7742068108789715	[21]	[28,42,34,42]	9	hSpCas9	negative selection	8974789
2644786	2644809	9	-	27260156	SU8686	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.1250907952663366	[719]	[566,721,900,986]	2	hSpCas9	negative selection	8974790
2644799	2644822	9	+	27260156	SU8686	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.5616306280325708	[359]	[249,257,233,215]	-7	hSpCas9	negative selection	9039036
2643946	2643969	9	-	27260156	SU8686	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-0.0020323737753069615	[1993]	[1894,1700,2132,2245]	0	hSpCas9	negative selection	9039037
2643892	2643915	9	+	27260156	SU8686	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.036664177199307764	[485]	[489,429,512,441]	0	hSpCas9	negative selection	9039038
2622188	2622211	9	+	27260156	SKES1	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	-0.13809590296085836	[405]	[357,452,392,282]	-3	hSpCas9	negative selection	9096039
2622260	2622283	9	-	27260156	SKES1	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.7890200901528441	[21]	[13,35,54,41]	9	hSpCas9	negative selection	9096040
2644786	2644809	9	-	27260156	SKES1	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	-0.2710040019437832	[719]	[644,738,576,454]	-5	hSpCas9	negative selection	9096041
2644799	2644822	9	+	27260156	SKES1	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.5127334391618183	[359]	[239,263,268,232]	-8	hSpCas9	negative selection	9160287
2643946	2643969	9	-	27260156	SKES1	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-0.17002362992722175	[1993]	[2020,2084,1580,1476]	-4	hSpCas9	negative selection	9160288
2643892	2643915	9	+	27260156	SKES1	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.35463073852224103	[485]	[457,356,373,336]	-7	hSpCas9	negative selection	9160289
2622188	2622211	9	+	27260156	TOV112D	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.14180639251975397	[405]	[380,504,432,481]	2	hSpCas9	negative selection	9217290
2622260	2622283	9	-	27260156	TOV112D	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	-0.7542372607201022	[21]	[3,22,16,9]	-9	hSpCas9	negative selection	9217291
2644786	2644809	9	-	27260156	TOV112D	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	0.08780399279909112	[719]	[1019,1165,524,480]	1	hSpCas9	negative selection	9217292
2644799	2644822	9	+	27260156	TOV112D	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.5330360644880997	[359]	[282,321,159,251]	-8	hSpCas9	negative selection	9281538
2643946	2643969	9	-	27260156	TOV112D	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.02640302793379279	[1993]	[2579,2299,1946,1433]	0	hSpCas9	negative selection	9281539
2643892	2643915	9	+	27260156	TOV112D	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.07872472866034876	[485]	[523,487,532,313]	-1	hSpCas9	negative selection	9281540
2622188	2622211	9	+	27260156	TC71	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.06597365564765856	[405]	[520,420,481,391]	1	hSpCas9	negative selection	9338541
2622260	2622283	9	-	27260156	TC71	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.2896812322044955	[21]	[37,15,41,17]	7	hSpCas9	negative selection	9338542
2644786	2644809	9	-	27260156	TC71	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	-0.15977072455532937	[719]	[612,746,618,794]	-4	hSpCas9	negative selection	9338543
2644799	2644822	9	+	27260156	TC71	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.5657557692003033	[359]	[226,243,279,293]	-9	hSpCas9	negative selection	9402789
2643946	2643969	9	-	27260156	TC71	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	-0.18465946604686523	[1993]	[1583,1850,2127,1962]	-5	hSpCas9	negative selection	9402790
2643892	2643915	9	+	27260156	TC71	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	-0.23625388830699018	[485]	[513,429,366,459]	-6	hSpCas9	negative selection	9402791
2622188	2622211	9	+	27260156	TC32	viability	CCATGGGCACGTCCGCGCTCTGG	VLDLR	ENSG00000147852	0.24400246097186448	[405]	[325,393,509,606]	4	hSpCas9	negative selection	9459792
2622260	2622283	9	-	27260156	TC32	viability	TCCTCACTCACCGGTTCCGGTGG	VLDLR	ENSG00000147852	0.3438713420139763	[21]	[1,15,24,69]	6	hSpCas9	negative selection	9459793
2644786	2644809	9	-	27260156	TC32	viability	CACACTCGTAGCCTATAACTAGG	VLDLR	ENSG00000147852	-0.16903252084345427	[719]	[559,474,721,692]	-3	hSpCas9	negative selection	9459794
2644799	2644822	9	+	27260156	TC32	viability	TACGAGTGTGACTGTGCAGCTGG	VLDLR	ENSG00000147852	-0.16651132992276152	[359]	[391,169,369,305]	-3	hSpCas9	negative selection	9524040
2643946	2643969	9	-	27260156	TC32	viability	TACACTTACGACACTCTTTCAGG	VLDLR	ENSG00000147852	0.1998252257546076	[1993]	[2051,1790,2713,2165]	3	hSpCas9	negative selection	9524041
2643892	2643915	9	+	27260156	TC32	viability	TATCAGCAAAGTATGTAACCAGG	VLDLR	ENSG00000147852	0.19356580512828733	[485]	[568,445,654,425]	3	hSpCas9	negative selection	9524042
2635484	2635507	9	-	27869803	HPAFII	viability after 27 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	2.0945251660082986	[185]	[625,243,NaN]	9	hSpCas9	negative selection	9605659
2639913	2639936	9	-	27869803	HPAFII	viability after 27 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	1.351732057854856	[207]	[481,109,NaN]	9	hSpCas9	negative selection	9605660
2641417	2641440	9	-	27869803	HPAFII	viability after 27 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.793701794444523	[635]	[499,645,NaN]	6	hSpCas9	negative selection	9605661
2643234	2643257	9	+	27869803	HPAFII	viability after 27 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.44820524451316857	[422]	[276,67,NaN]	-3	hSpCas9	negative selection	9605662
2643680	2643703	9	-	27869803	HPAFII	viability after 27 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	-0.5080044223072262	[149]	[43,64,NaN]	-4	hSpCas9	negative selection	9605663
2643898	2643921	9	+	27869803	HPAFII	viability after 27 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.2653190641105278	[263]	[126,199,NaN]	2	hSpCas9	negative selection	9605664
2635484	2635507	9	-	27869803	HPAFII	viability after 15 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	1.3872318419879366	[185]	[771,367,NaN]	9	hSpCas9	negative selection	9688108
2639913	2639936	9	-	27869803	HPAFII	viability after 15 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	0.9477686271403944	[207]	[683,273,NaN]	9	hSpCas9	negative selection	9688109
2641417	2641440	9	-	27869803	HPAFII	viability after 15 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.4077529836915572	[635]	[1055,813,NaN]	5	hSpCas9	negative selection	9688110
2643234	2643257	9	+	27869803	HPAFII	viability after 15 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.1566689181011942	[422]	[532,329,NaN]	-2	hSpCas9	negative selection	9688111
2643680	2643703	9	-	27869803	HPAFII	viability after 15 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	0.4246765489756441	[149]	[253,192,NaN]	5	hSpCas9	negative selection	9688112
2643898	2643921	9	+	27869803	HPAFII	viability after 15 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.05468122083642134	[263]	[528,148,NaN]	0	hSpCas9	negative selection	9688113
2635484	2635507	9	-	27869803	ASPC1	viability after 36 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	0.5608531897314927	[533]	[312,374,165]	5	hSpCas9	negative selection	9770557
2639913	2639936	9	-	27869803	ASPC1	viability after 36 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	0.9943846894901154	[794]	[715,501,472]	8	hSpCas9	negative selection	9770558
2641417	2641440	9	-	27869803	ASPC1	viability after 36 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.9333879876382738	[1270]	[517,1226,767]	8	hSpCas9	negative selection	9770559
2643234	2643257	9	+	27869803	ASPC1	viability after 36 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.21423417059887928	[1173]	[608,297,213]	-2	hSpCas9	negative selection	9770560
2643680	2643703	9	-	27869803	ASPC1	viability after 36 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	-0.3416243059552949	[323]	[66,165,42]	-4	hSpCas9	negative selection	9770561
2643898	2643921	9	+	27869803	ASPC1	viability after 36 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	-0.7537201820588127	[656]	[219,122,85]	-6	hSpCas9	negative selection	9770562
2635484	2635507	9	-	27869803	PATU8988S	viability after 35 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	0.18725859192127045	[495]	[205,248,NaN]	2	hSpCas9	negative selection	9853006
2639913	2639936	9	-	27869803	PATU8988S	viability after 35 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	-0.14945111312617843	[599]	[160,274,NaN]	-1	hSpCas9	negative selection	9853007
2641417	2641440	9	-	27869803	PATU8988S	viability after 35 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.06643585138301344	[1073]	[425,479,NaN]	0	hSpCas9	negative selection	9853008
2643234	2643257	9	+	27869803	PATU8988S	viability after 35 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	1.1813653146835499	[795]	[975,476,NaN]	9	hSpCas9	negative selection	9853009
2643680	2643703	9	-	27869803	PATU8988S	viability after 35 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	0.6537662703373699	[337]	[287,139,NaN]	7	hSpCas9	negative selection	9853010
2643898	2643921	9	+	27869803	PATU8988S	viability after 35 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.2359039396391993	[568]	[214,324,NaN]	2	hSpCas9	negative selection	9853011
2635484	2635507	9	-	27869803	PATU8988S	viability after 31 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	0.7085016337777493	[495]	[265,395,NaN]	8	hSpCas9	negative selection	9935455
2639913	2639936	9	-	27869803	PATU8988S	viability after 31 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	-0.2384828251345608	[599]	[171,241,NaN]	-3	hSpCas9	negative selection	9935456
2641417	2641440	9	-	27869803	PATU8988S	viability after 31 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.23976413019532927	[1073]	[495,517,NaN]	3	hSpCas9	negative selection	9935457
2643234	2643257	9	+	27869803	PATU8988S	viability after 31 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.687290910406232	[795]	[584,416,NaN]	7	hSpCas9	negative selection	9935458
2643680	2643703	9	-	27869803	PATU8988S	viability after 31 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	0.4377795186755815	[337]	[160,209,NaN]	5	hSpCas9	negative selection	9935459
2643898	2643921	9	+	27869803	PATU8988S	viability after 31 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.3911206308189583	[568]	[198,422,NaN]	5	hSpCas9	negative selection	9935460
2635484	2635507	9	-	27869803	HPAFII	viability after 35 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	1.9197999916601183	[185]	[447,252,NaN]	9	hSpCas9	negative selection	10017904
2639913	2639936	9	-	27869803	HPAFII	viability after 35 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	1.8275366462263536	[207]	[559,163,NaN]	9	hSpCas9	negative selection	10017905
2641417	2641440	9	-	27869803	HPAFII	viability after 35 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.9783718612693972	[635]	[417,877,NaN]	6	hSpCas9	negative selection	10017906
2643234	2643257	9	+	27869803	HPAFII	viability after 35 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.43936654927927116	[422]	[235,69,NaN]	-3	hSpCas9	negative selection	10017907
2643680	2643703	9	-	27869803	HPAFII	viability after 35 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	0.003221790490831933	[149]	[53,100,NaN]	0	hSpCas9	negative selection	10017908
2643898	2643921	9	+	27869803	HPAFII	viability after 35 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.041542000725781444	[263]	[66,216,NaN]	0	hSpCas9	negative selection	10017909
2635484	2635507	9	-	27869803	HPAFII	viability after 31 days	TACAGCGACCATTTGTGCACTGG	VLDLR	ENSG00000147852	2.2811108580534425	[185]	[671,327,NaN]	9	hSpCas9	negative selection	10100353
2639913	2639936	9	-	27869803	HPAFII	viability after 31 days	TCCATCACACTTCCATCGGCTGG	VLDLR	ENSG00000147852	1.3370833798732493	[207]	[426,150,NaN]	8	hSpCas9	negative selection	10100354
2641417	2641440	9	-	27869803	HPAFII	viability after 31 days	CTGGGATACACTGAGTAGAATGG	VLDLR	ENSG00000147852	0.9050099147381245	[635]	[553,792,NaN]	6	hSpCas9	negative selection	10100355
2643234	2643257	9	+	27869803	HPAFII	viability after 31 days	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-1.1216353620084472	[422]	[155,57,NaN]	-6	hSpCas9	negative selection	10100356
2643680	2643703	9	-	27869803	HPAFII	viability after 31 days	CATTACACTGCCTGCTGCCATGG	VLDLR	ENSG00000147852	-0.27413600057327403	[149]	[60,78,NaN]	-2	hSpCas9	negative selection	10100357
2643898	2643921	9	+	27869803	HPAFII	viability after 31 days	CAAAGTATGTAACCAGGAGCAGG	VLDLR	ENSG00000147852	0.6868657430739666	[263]	[193,286,NaN]	5	hSpCas9	negative selection	10100358
2641478	2641501	9	+	28162770	P31FUJ	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-1.222886735549296	[144]	[72]	-7	hSpCas9	negative selection	10263490
2643203	2643226	9	-	28162770	P31FUJ	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	0.37795976573883305	[350]	[535]	4	hSpCas9	negative selection	10263491
2643234	2643257	9	+	28162770	P31FUJ	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.4269688839553154	[237]	[375]	5	hSpCas9	negative selection	10263492
2643319	2643342	9	-	28162770	P31FUJ	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.6217673560640576	[218]	[395]	7	hSpCas9	negative selection	10263493
2643457	2643480	9	+	28162770	P31FUJ	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.6569382874367047	[298]	[553]	7	hSpCas9	negative selection	10263494
2644832	2644855	9	+	28162770	P31FUJ	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	0.2894685181894928	[242]	[348]	3	hSpCas9	negative selection	10263495
2646542	2646565	9	-	28162770	P31FUJ	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	0.2475890328585647	[409]	[571]	2	hSpCas9	negative selection	10263496
2635551	2635574	9	+	28162770	P31FUJ	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	0.8080700770011495	[86]	[178]	8	hSpCas9	negative selection	10263497
2639933	2639956	9	+	28162770	P31FUJ	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	0.39198627679996567	[130]	[201]	4	hSpCas9	negative selection	10263498
2641391	2641414	9	+	28162770	P31FUJ	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	0.08522143601706755	[295]	[368]	0	hSpCas9	negative selection	10263499
2641478	2641501	9	+	28162770	TF1	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10432856
2643203	2643226	9	-	28162770	TF1	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	NaN	[NaN]	[439]	1	hSpCas9	negative selection	10432857
2643234	2643257	9	+	28162770	TF1	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	NaN	[NaN]	[117]	1	hSpCas9	negative selection	10432858
2643319	2643342	9	-	28162770	TF1	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	NaN	[NaN]	[220]	1	hSpCas9	negative selection	10432859
2643457	2643480	9	+	28162770	TF1	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	NaN	[NaN]	[335]	1	hSpCas9	negative selection	10432860
2644832	2644855	9	+	28162770	TF1	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	NaN	[NaN]	[392]	1	hSpCas9	negative selection	10432861
2646542	2646565	9	-	28162770	TF1	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	NaN	[NaN]	[366]	1	hSpCas9	negative selection	10432862
2635551	2635574	9	+	28162770	TF1	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10432863
2639933	2639956	9	+	28162770	TF1	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	NaN	[NaN]	[206]	1	hSpCas9	negative selection	10432864
2641391	2641414	9	+	28162770	TF1	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	NaN	[NaN]	[300]	1	hSpCas9	negative selection	10432865
2641478	2641501	9	+	28162770	SKM1	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-0.7453804164190929	[54]	[57]	-5	hSpCas9	negative selection	10602222
2643203	2643226	9	-	28162770	SKM1	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	-0.19815018390725428	[60]	[93]	-2	hSpCas9	negative selection	10602223
2643234	2643257	9	+	28162770	SKM1	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.4857183101575732	[79]	[100]	-4	hSpCas9	negative selection	10602224
2643319	2643342	9	-	28162770	SKM1	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.5588200859189253	[47]	[124]	5	hSpCas9	negative selection	10602225
2643457	2643480	9	+	28162770	SKM1	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	-0.04687510886220858	[96]	[165]	0	hSpCas9	negative selection	10602226
2644832	2644855	9	+	28162770	SKM1	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	0.24671105206200894	[81]	[171]	2	hSpCas9	negative selection	10602227
2646542	2646565	9	-	28162770	SKM1	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	0.4667595329301575	[87]	[214]	4	hSpCas9	negative selection	10602228
2635551	2635574	9	+	28162770	SKM1	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	0.24212863939771023	[32]	[68]	2	hSpCas9	negative selection	10602229
2639933	2639956	9	+	28162770	SKM1	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	0.6185708933639757	[27]	[75]	6	hSpCas9	negative selection	10602230
2641391	2641414	9	+	28162770	SKM1	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	-0.2731084520083711	[53]	[78]	-2	hSpCas9	negative selection	10602231
2641478	2641501	9	+	28162770	SKM1	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-0.7453804164190929	[54]	[57]	-5	hSpCas9	negative selection	10771588
2643203	2643226	9	-	28162770	SKM1	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	-0.19815018390725428	[60]	[93]	-2	hSpCas9	negative selection	10771589
2643234	2643257	9	+	28162770	SKM1	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.4857183101575732	[79]	[100]	-4	hSpCas9	negative selection	10771590
2643319	2643342	9	-	28162770	SKM1	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.5588200859189253	[47]	[124]	5	hSpCas9	negative selection	10771591
2643457	2643480	9	+	28162770	SKM1	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	-0.04687510886220858	[96]	[165]	0	hSpCas9	negative selection	10771592
2644832	2644855	9	+	28162770	SKM1	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	0.24671105206200894	[81]	[171]	2	hSpCas9	negative selection	10771593
2646542	2646565	9	-	28162770	SKM1	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	0.4667595329301575	[87]	[214]	4	hSpCas9	negative selection	10771594
2635551	2635574	9	+	28162770	SKM1	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	0.24212863939771023	[32]	[68]	2	hSpCas9	negative selection	10771595
2639933	2639956	9	+	28162770	SKM1	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	0.6185708933639757	[27]	[75]	6	hSpCas9	negative selection	10771596
2641391	2641414	9	+	28162770	SKM1	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	-0.2731084520083711	[53]	[78]	-2	hSpCas9	negative selection	10771597
2641478	2641501	9	+	28162770	PL21	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-1.4308352839886727	[222]	[35]	-7	hSpCas9	negative selection	10940954
2643203	2643226	9	-	28162770	PL21	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	0.750692084424645	[197]	[144]	6	hSpCas9	negative selection	10940955
2643234	2643257	9	+	28162770	PL21	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.282016621543728	[273]	[144]	2	hSpCas9	negative selection	10940956
2643319	2643342	9	-	28162770	PL21	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.21625927985259713	[177]	[89]	2	hSpCas9	negative selection	10940957
2643457	2643480	9	+	28162770	PL21	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	1.0417496434134854	[326]	[292]	8	hSpCas9	negative selection	10940958
2644832	2644855	9	+	28162770	PL21	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	-0.21149128334627443	[281]	[105]	-1	hSpCas9	negative selection	10940959
2646542	2646565	9	-	28162770	PL21	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	1.0494607019916522	[241]	[217]	8	hSpCas9	negative selection	10940960
2635551	2635574	9	+	28162770	PL21	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	0.5913303718137961	[60]	[39]	5	hSpCas9	negative selection	10940961
2639933	2639956	9	+	28162770	PL21	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	1.0268080116037583	[105]	[93]	8	hSpCas9	negative selection	10940962
2641391	2641414	9	+	28162770	PL21	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	0.3891734388793373	[199]	[113]	3	hSpCas9	negative selection	10940963
2641478	2641501	9	+	28162770	P31FUJ	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-1.222886735549296	[144]	[72]	-7	hSpCas9	negative selection	11110320
2643203	2643226	9	-	28162770	P31FUJ	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	0.37795976573883305	[350]	[535]	4	hSpCas9	negative selection	11110321
2643234	2643257	9	+	28162770	P31FUJ	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.4269688839553154	[237]	[375]	5	hSpCas9	negative selection	11110322
2643319	2643342	9	-	28162770	P31FUJ	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.6217673560640576	[218]	[395]	7	hSpCas9	negative selection	11110323
2643457	2643480	9	+	28162770	P31FUJ	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.6569382874367047	[298]	[553]	7	hSpCas9	negative selection	11110324
2644832	2644855	9	+	28162770	P31FUJ	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	0.2894685181894928	[242]	[348]	3	hSpCas9	negative selection	11110325
2646542	2646565	9	-	28162770	P31FUJ	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	0.2475890328585647	[409]	[571]	2	hSpCas9	negative selection	11110326
2635551	2635574	9	+	28162770	P31FUJ	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	0.8080700770011495	[86]	[178]	8	hSpCas9	negative selection	11110327
2639933	2639956	9	+	28162770	P31FUJ	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	0.39198627679996567	[130]	[201]	4	hSpCas9	negative selection	11110328
2641391	2641414	9	+	28162770	P31FUJ	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	0.08522143601706755	[295]	[368]	0	hSpCas9	negative selection	11110329
2641478	2641501	9	+	28162770	OCIAML5	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-2.46504344775475	[103]	[33]	-8	hSpCas9	negative selection	11279686
2643203	2643226	9	-	28162770	OCIAML5	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	0.6322919889187535	[192]	[539]	5	hSpCas9	negative selection	11279687
2643234	2643257	9	+	28162770	OCIAML5	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	1.063163325657251	[91]	[346]	8	hSpCas9	negative selection	11279688
2643319	2643342	9	-	28162770	OCIAML5	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.4246199355610125	[148]	[360]	3	hSpCas9	negative selection	11279689
2643457	2643480	9	+	28162770	OCIAML5	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.03320121304472634	[241]	[446]	0	hSpCas9	negative selection	11279690
2644832	2644855	9	+	28162770	OCIAML5	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	0.5300061650670604	[248]	[648]	4	hSpCas9	negative selection	11279691
2646542	2646565	9	-	28162770	OCIAML5	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	0.7930169222947301	[187]	[587]	7	hSpCas9	negative selection	11279692
2635551	2635574	9	+	28162770	OCIAML5	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	0.745495966636793	[37]	[114]	6	hSpCas9	negative selection	11279693
2639933	2639956	9	+	28162770	OCIAML5	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	0.6412654543915909	[64]	[182]	5	hSpCas9	negative selection	11279694
2641391	2641414	9	+	28162770	OCIAML5	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	0.6714953851930159	[127]	[367]	6	hSpCas9	negative selection	11279695
2641478	2641501	9	+	28162770	EOL1	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-0.7369562840236149	[328]	[103]	-5	hSpCas9	negative selection	11449052
2643203	2643226	9	-	28162770	EOL1	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	-0.7068076346350729	[315]	[101]	-5	hSpCas9	negative selection	11449053
2643234	2643257	9	+	28162770	EOL1	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.8541584436791367	[440]	[419]	7	hSpCas9	negative selection	11449054
2643319	2643342	9	-	28162770	EOL1	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.6383340403492123	[388]	[318]	6	hSpCas9	negative selection	11449055
2643457	2643480	9	+	28162770	EOL1	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	-0.04059347121781376	[735]	[376]	0	hSpCas9	negative selection	11449056
2644832	2644855	9	+	28162770	EOL1	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	0.28560764979055353	[530]	[340]	2	hSpCas9	negative selection	11449057
2646542	2646565	9	-	28162770	EOL1	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	-0.1525766545601205	[364]	[172]	-1	hSpCas9	negative selection	11449058
2635551	2635574	9	+	28162770	EOL1	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	-0.2025641463328045	[82]	[37]	-1	hSpCas9	negative selection	11449059
2639933	2639956	9	+	28162770	EOL1	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	-0.4677696512082259	[125]	[47]	-3	hSpCas9	negative selection	11449060
2641391	2641414	9	+	28162770	EOL1	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	-0.11197810445457945	[239]	[116]	-1	hSpCas9	negative selection	11449061
2641478	2641501	9	+	28162770	MOLM13	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-3.28699812061889	[242]	[17]	-8	hSpCas9	negative selection	11618418
2643203	2643226	9	-	28162770	MOLM13	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	-0.2033288525269964	[335]	[210]	-1	hSpCas9	negative selection	11618419
2643234	2643257	9	+	28162770	MOLM13	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.4494639070743943	[393]	[388]	3	hSpCas9	negative selection	11618420
2643319	2643342	9	-	28162770	MOLM13	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.7454233570734878	[329]	[399]	5	hSpCas9	negative selection	11618421
2643457	2643480	9	+	28162770	MOLM13	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.6656665036267785	[455]	[522]	5	hSpCas9	negative selection	11618422
2644832	2644855	9	+	28162770	MOLM13	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	0.6363247648464045	[322]	[362]	5	hSpCas9	negative selection	11618423
2646542	2646565	9	-	28162770	MOLM13	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	-0.23051636609058723	[442]	[272]	-1	hSpCas9	negative selection	11618424
2635551	2635574	9	+	28162770	MOLM13	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	0.6240085834618607	[104]	[116]	5	hSpCas9	negative selection	11618425
2639933	2639956	9	+	28162770	MOLM13	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	1.3944683120752095	[130]	[248]	9	hSpCas9	negative selection	11618426
2641391	2641414	9	+	28162770	MOLM13	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	-0.1289472194648691	[365]	[241]	-1	hSpCas9	negative selection	11618427
2641478	2641501	9	+	28162770	HEL	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-2.952640284666138	[277]	[22]	-8	hSpCas9	negative selection	11787784
2643203	2643226	9	-	28162770	HEL	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	0.9317165050864328	[247]	[302]	7	hSpCas9	negative selection	11787785
2643234	2643257	9	+	28162770	HEL	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.700250878414835	[344]	[135]	-4	hSpCas9	negative selection	11787786
2643319	2643342	9	-	28162770	HEL	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	-0.3524761054342661	[300]	[150]	-2	hSpCas9	negative selection	11787787
2643457	2643480	9	+	28162770	HEL	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	-0.2356693874506871	[488]	[265]	-2	hSpCas9	negative selection	11787788
2644832	2644855	9	+	28162770	HEL	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	-0.8738366937405491	[308]	[107]	-5	hSpCas9	negative selection	11787789
2646542	2646565	9	-	28162770	HEL	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	0.3957568314519292	[285]	[240]	3	hSpCas9	negative selection	11787790
2635551	2635574	9	+	28162770	HEL	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	-0.5560410321141405	[100]	[43]	-4	hSpCas9	negative selection	11787791
2639933	2639956	9	+	28162770	HEL	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	-0.357261167999643	[121]	[60]	-3	hSpCas9	negative selection	11787792
2641391	2641414	9	+	28162770	HEL	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	-1.9037495209061635	[332]	[56]	-7	hSpCas9	negative selection	11787793
2641478	2641501	9	+	28162770	MV411	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-1.9151826500363036	[196]	[43]	-8	hSpCas9	negative selection	11957150
2643203	2643226	9	-	28162770	MV411	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	0.15213059068704782	[218]	[204]	1	hSpCas9	negative selection	11957151
2643234	2643257	9	+	28162770	MV411	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.20591828134450862	[281]	[273]	1	hSpCas9	negative selection	11957152
2643319	2643342	9	-	28162770	MV411	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.4529066690827547	[195]	[225]	4	hSpCas9	negative selection	11957153
2643457	2643480	9	+	28162770	MV411	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.14925715684387186	[303]	[283]	1	hSpCas9	negative selection	11957154
2644832	2644855	9	+	28162770	MV411	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	0.24258815112137933	[297]	[296]	2	hSpCas9	negative selection	11957155
2646542	2646565	9	-	28162770	MV411	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	-0.06210681964875453	[289]	[233]	0	hSpCas9	negative selection	11957156
2635551	2635574	9	+	28162770	MV411	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	0.5895435276077681	[70]	[89]	5	hSpCas9	negative selection	11957157
2639933	2639956	9	+	28162770	MV411	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	0.1219066686989162	[107]	[98]	1	hSpCas9	negative selection	11957158
2641391	2641414	9	+	28162770	MV411	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	0.5813382873362137	[191]	[241]	5	hSpCas9	negative selection	11957159
2641478	2641501	9	+	28162770	MONOMAC1	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-0.8128933557264936	[117]	[76]	-6	hSpCas9	negative selection	12126516
2643203	2643226	9	-	28162770	MONOMAC1	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	0.5444301393415931	[127]	[213]	5	hSpCas9	negative selection	12126517
2643234	2643257	9	+	28162770	MONOMAC1	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.5680072701400862	[172]	[293]	5	hSpCas9	negative selection	12126518
2643319	2643342	9	-	28162770	MONOMAC1	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.4304502703081595	[155]	[240]	4	hSpCas9	negative selection	12126519
2643457	2643480	9	+	28162770	MONOMAC1	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.9779680717471118	[251]	[568]	8	hSpCas9	negative selection	12126520
2644832	2644855	9	+	28162770	MONOMAC1	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	-0.9588771098647892	[194]	[114]	-6	hSpCas9	negative selection	12126521
2646542	2646565	9	-	28162770	MONOMAC1	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	0.502209081157494	[185]	[301]	5	hSpCas9	negative selection	12126522
2635551	2635574	9	+	28162770	MONOMAC1	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	0.4641612394886878	[42]	[67]	4	hSpCas9	negative selection	12126523
2639933	2639956	9	+	28162770	MONOMAC1	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	1.061697421340615	[55]	[133]	8	hSpCas9	negative selection	12126524
2641391	2641414	9	+	28162770	MONOMAC1	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	-0.23078563841409389	[172]	[168]	-2	hSpCas9	negative selection	12126525
2641478	2641501	9	+	28162770	OCIAML2	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-2.566845140501464	[30]	[28]	-8	hSpCas9	negative selection	12295882
2643203	2643226	9	-	28162770	OCIAML2	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	0.4126739500487415	[36]	[272]	4	hSpCas9	negative selection	12295883
2643234	2643257	9	+	28162770	OCIAML2	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	0.296924088757468	[41]	[285]	3	hSpCas9	negative selection	12295884
2643319	2643342	9	-	28162770	OCIAML2	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.5633175066811764	[41]	[343]	5	hSpCas9	negative selection	12295885
2643457	2643480	9	+	28162770	OCIAML2	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	1.1843526025129432	[61]	[780]	9	hSpCas9	negative selection	12295886
2644832	2644855	9	+	28162770	OCIAML2	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	0.5488400389560637	[45]	[372]	5	hSpCas9	negative selection	12295887
2646542	2646565	9	-	28162770	OCIAML2	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	0.24208822267736746	[44]	[294]	2	hSpCas9	negative selection	12295888
2635551	2635574	9	+	28162770	OCIAML2	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	0.8512982696452012	[10]	[109]	8	hSpCas9	negative selection	12295889
2639933	2639956	9	+	28162770	OCIAML2	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	0.75643908330376	[10]	[102]	7	hSpCas9	negative selection	12295890
2641391	2641414	9	+	28162770	OCIAML2	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	-0.24181113474628027	[31]	[149]	-2	hSpCas9	negative selection	12295891
2641478	2641501	9	+	28162770	OCIAML3	viability	GGAGAAGATGAAGAAAACTGTGG	VLDLR	ENSG00000147852	-0.22203886293720537	[50]	[131]	-2	hSpCas9	negative selection	12465248
2643203	2643226	9	-	28162770	OCIAML3	viability	CAAAGTTCCTGGAGATGCAGCGG	VLDLR	ENSG00000147852	0.5199485489729228	[72]	[315]	5	hSpCas9	negative selection	12465249
2643234	2643257	9	+	28162770	OCIAML3	viability	GGCCAGGATGACTGCAGCGATGG	VLDLR	ENSG00000147852	-0.31788323504992555	[63]	[154]	-2	hSpCas9	negative selection	12465250
2643319	2643342	9	-	28162770	OCIAML3	viability	CCAGCTGATGGGGATGCAGGAGG	VLDLR	ENSG00000147852	0.7046506752403521	[49]	[245]	6	hSpCas9	negative selection	12465251
2643457	2643480	9	+	28162770	OCIAML3	viability	GCGAGTGCATCCATAAGAAGTGG	VLDLR	ENSG00000147852	0.7820079701254967	[88]	[461]	7	hSpCas9	negative selection	12465252
2644832	2644855	9	+	28162770	OCIAML3	viability	ATAGATAGGAAAACCTGTGGAGG	VLDLR	ENSG00000147852	0.3027230890641338	[75]	[282]	3	hSpCas9	negative selection	12465253
2646542	2646565	9	-	28162770	OCIAML3	viability	CAGACTACAAACCCAGACAGTGG	VLDLR	ENSG00000147852	0.020702203791044926	[79]	[244]	0	hSpCas9	negative selection	12465254
2635551	2635574	9	+	28162770	OCIAML3	viability	GGCAGTGATGAAAAGAACTGTGG	VLDLR	ENSG00000147852	-0.719538522408022	[23]	[43]	-5	hSpCas9	negative selection	12465255
2639933	2639956	9	+	28162770	OCIAML3	viability	GGAGATCCTGACTGCGAAGATGG	VLDLR	ENSG00000147852	0.5306881071251516	[35]	[156]	5	hSpCas9	negative selection	12465256
2641391	2641414	9	+	28162770	OCIAML3	viability	CGCATACATGAAATCAGCTGTGG	VLDLR	ENSG00000147852	0.23070844239487823	[58]	[208]	2	hSpCas9	negative selection	12465257