Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:9525
• Symbol:VPS4B
• Description:vacuolar protein sorting 4 homolog B

DataSource: http://genomecrispr.dkfz.de/#!/results/VPS4B

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
63411532	63411555	18	-	26472758	Jiyoye	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	1.3376344482527964	[84]	[161]	7	hSpCas9	negative selection	180169
63397133	63397156	18	-	26472758	Jiyoye	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	0.40717538150587335	[132]	[132]	3	hSpCas9	negative selection	180170
63410289	63410312	18	-	26472758	Jiyoye	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.1776935353831063	[135]	[115]	1	hSpCas9	negative selection	180171
63400684	63400707	18	-	26472758	Jiyoye	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	0.3118684214101459	[218]	[204]	2	hSpCas9	negative selection	180172
63400643	63400666	18	+	26472758	Jiyoye	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	1.4183735881107373	[384]	[775]	8	hSpCas9	negative selection	180173
63399302	63399325	18	-	26472758	Jiyoye	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	-0.2581854718572101	[451]	[284]	-2	hSpCas9	negative selection	180174
63399267	63399290	18	-	26472758	Jiyoye	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	0.11419866031464021	[184]	[150]	0	hSpCas9	negative selection	180175
63399251	63399274	18	+	26472758	Jiyoye	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.3547079616117379	[83]	[80]	2	hSpCas9	negative selection	180176
63393514	63393537	18	+	26472758	Jiyoye	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	-0.22085584110716866	[186]	[120]	-1	hSpCas9	negative selection	180177
63410317	63410340	18	-	26472758	Jiyoye	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.49178760922081494	[148]	[157]	3	hSpCas9	negative selection	180178
63411532	63411555	18	-	26472758	KBM7	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.441541263448393	[619,583]	[221,196]	-4	hSpCas9	negative selection	371287
63397133	63397156	18	-	26472758	KBM7	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	0.6960780912774027	[556,342]	[399,278]	7	hSpCas9	negative selection	371288
63410289	63410312	18	-	26472758	KBM7	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.04295473490651033	[445,342]	[189,188]	0	hSpCas9	negative selection	371289
63400684	63400707	18	-	26472758	KBM7	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	-0.18966541084695343	[1074,1050]	[517,369]	-2	hSpCas9	negative selection	371290
63400643	63400666	18	+	26472758	KBM7	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	0.12489390615521656	[2301,1513]	[955,967]	1	hSpCas9	negative selection	371291
63399302	63399325	18	-	26472758	KBM7	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	0.1570306650827884	[1566,1124]	[843,565]	1	hSpCas9	negative selection	371292
63399267	63399290	18	-	26472758	KBM7	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	0.17192170276501423	[559,341]	[287,185]	1	hSpCas9	negative selection	371293
63399251	63399274	18	+	26472758	KBM7	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.27930947801907996	[425,315]	[227,192]	3	hSpCas9	negative selection	371294
63393514	63393537	18	+	26472758	KBM7	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	0.06528192749067996	[618,809]	[319,391]	0	hSpCas9	negative selection	371295
63410317	63410340	18	-	26472758	KBM7	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.16207064522085185	[570,570]	[313,290]	1	hSpCas9	negative selection	371296
63411532	63411555	18	-	26472758	Raji	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	0.6718819335350401	[283]	[104]	6	hSpCas9	negative selection	562405
63397133	63397156	18	-	26472758	Raji	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	-0.044619558071450405	[319]	[71]	0	hSpCas9	negative selection	562406
63410289	63410312	18	-	26472758	Raji	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.42457371125429866	[121]	[37]	4	hSpCas9	negative selection	562407
63400684	63400707	18	-	26472758	Raji	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	0.40031942692125544	[381]	[116]	4	hSpCas9	negative selection	562408
63400643	63400666	18	+	26472758	Raji	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	0.15291187523097127	[1309]	[337]	1	hSpCas9	negative selection	562409
63399302	63399325	18	-	26472758	Raji	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	-0.18837250316060106	[436]	[88]	-1	hSpCas9	negative selection	562410
63399267	63399290	18	-	26472758	Raji	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	0.5372180365805237	[290]	[97]	5	hSpCas9	negative selection	562411
63399251	63399274	18	+	26472758	Raji	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.19739370110619442	[232]	[61]	1	hSpCas9	negative selection	562412
63393514	63393537	18	+	26472758	Raji	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	0.29628621163017865	[385]	[109]	3	hSpCas9	negative selection	562413
63410317	63410340	18	-	26472758	Raji	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.7801219961831964	[270]	[107]	7	hSpCas9	negative selection	562414
63411532	63411555	18	-	26472758	K562	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	0.26228514845996065	[641]	[649]	2	hSpCas9	negative selection	753523
63397133	63397156	18	-	26472758	K562	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	1.2713857752667161	[317]	[647]	9	hSpCas9	negative selection	753524
63410289	63410312	18	-	26472758	K562	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.9340786070542965	[371]	[599]	7	hSpCas9	negative selection	753525
63400684	63400707	18	-	26472758	K562	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	0.3006132671190602	[855]	[889]	2	hSpCas9	negative selection	753526
63400643	63400666	18	+	26472758	K562	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	0.481653956632913	[1560]	[1839]	4	hSpCas9	negative selection	753527
63399302	63399325	18	-	26472758	K562	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	0.05160059208084111	[1190]	[1041]	0	hSpCas9	negative selection	753528
63399267	63399290	18	-	26472758	K562	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	0.5255294237403751	[422]	[513]	4	hSpCas9	negative selection	753529
63399251	63399274	18	+	26472758	K562	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	1.1619565674744738	[278]	[526]	8	hSpCas9	negative selection	753530
63393514	63393537	18	+	26472758	K562	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	0.5875451833569879	[580]	[736]	5	hSpCas9	negative selection	753531
63410317	63410340	18	-	26472758	K562	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.4753577254308785	[552]	[648]	4	hSpCas9	negative selection	753532
63393464	63393487	18	+	26627737	DLD1	viability	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	-1.0803015079083433	[303]	[31,55,46]	-7	hSpCas9	negative selection	801890
63399251	63399274	18	+	26627737	DLD1	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.5555998073210023	[320]	[69,204,166]	5	hSpCas9	negative selection	801891
63400069	63400092	18	-	26627737	DLD1	viability	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.1783246049622541	[276]	[72,76,136]	1	hSpCas9	negative selection	801892
63400652	63400675	18	-	26627737	DLD1	viability	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	-0.7004045257569198	[601]	[124,82,134]	-6	hSpCas9	negative selection	801893
63410289	63410312	18	-	26627737	DLD1	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.27435190120580305	[613]	[215,253,227]	3	hSpCas9	negative selection	801894
63411532	63411555	18	-	26627737	DLD1	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	0.5429497778080512	[489]	[317,204,155]	5	hSpCas9	negative selection	801895
63393464	63393487	18	+	26627737	GBM cells	viability after 5 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	0.24528282903634696	[198]	[113,138]	4	hSpCas9	negative selection	884205
63399251	63399274	18	+	26627737	GBM cells	viability after 5 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.01587002123153497	[224]	[109,133]	0	hSpCas9	negative selection	884206
63400069	63400092	18	-	26627737	GBM cells	viability after 5 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.001550451563400057	[433]	[224,239]	0	hSpCas9	negative selection	884207
63400652	63400675	18	-	26627737	GBM cells	viability after 5 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	-0.05150409626375421	[285]	[126,168]	-1	hSpCas9	negative selection	884208
63410289	63410312	18	-	26627737	GBM cells	viability after 5 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-0.0048708098550114265	[521]	[229,327]	0	hSpCas9	negative selection	884209
63411532	63411555	18	-	26627737	GBM cells	viability after 5 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	1.106584790515368	[196]	[261,192]	9	hSpCas9	negative selection	884210
63393464	63393487	18	+	26627737	GBM cells	viability after 13 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	0.029343397918466296	[198]	[150,76]	0	hSpCas9	negative selection	966520
63399251	63399274	18	+	26627737	GBM cells	viability after 13 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.19479866518872768	[224]	[147,132]	2	hSpCas9	negative selection	966521
63400069	63400092	18	-	26627737	GBM cells	viability after 13 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.18124782282152196	[433]	[341,205]	2	hSpCas9	negative selection	966522
63400652	63400675	18	-	26627737	GBM cells	viability after 13 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	-0.08598322390658161	[285]	[127,160]	-1	hSpCas9	negative selection	966523
63410289	63410312	18	-	26627737	GBM cells	viability after 13 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-0.20890516835345796	[521]	[265,227]	-3	hSpCas9	negative selection	966524
63411532	63411555	18	-	26627737	GBM cells	viability after 13 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	1.7262177567880963	[196]	[410,306]	9	hSpCas9	negative selection	966525
63393464	63393487	18	+	26627737	GBM cells	viability after 21 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	0.03903508884525353	[198]	[120,101]	0	hSpCas9	negative selection	1048835
63399251	63399274	18	+	26627737	GBM cells	viability after 21 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.36504933294066805	[224]	[158,155]	4	hSpCas9	negative selection	1048836
63400069	63400092	18	-	26627737	GBM cells	viability after 21 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.201481623813471	[433]	[279,262]	2	hSpCas9	negative selection	1048837
63400652	63400675	18	-	26627737	GBM cells	viability after 21 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.06297991649181622	[285]	[201,125]	0	hSpCas9	negative selection	1048838
63410289	63410312	18	-	26627737	GBM cells	viability after 21 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-0.16924823151336865	[521]	[270,234]	-1	hSpCas9	negative selection	1048839
63411532	63411555	18	-	26627737	GBM cells	viability after 21 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	1.319957677745972	[196]	[285,249]	9	hSpCas9	negative selection	1048840
63393464	63393487	18	+	26627737	RPE1	viability after 9 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	1.7695874230236666	[79]	[63,112]	8	hSpCas9	negative selection	1131150
63399251	63399274	18	+	26627737	RPE1	viability after 9 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.2794997275107862	[294]	[160,48]	2	hSpCas9	negative selection	1131151
63400069	63400092	18	-	26627737	RPE1	viability after 9 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.06639168378563703	[1099]	[396,240]	0	hSpCas9	negative selection	1131152
63400652	63400675	18	-	26627737	RPE1	viability after 9 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.9093053070761811	[438]	[258,256]	6	hSpCas9	negative selection	1131153
63410289	63410312	18	-	26627737	RPE1	viability after 9 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-1.318963385037838	[2495]	[262,377]	-7	hSpCas9	negative selection	1131154
63411532	63411555	18	-	26627737	RPE1	viability after 9 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	0.7887784759031989	[672]	[332,403]	5	hSpCas9	negative selection	1131155
63393464	63393487	18	+	26627737	RPE1	viability after 12 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	1.3881476957423624	[79]	[64,46]	7	hSpCas9	negative selection	1213465
63399251	63399274	18	+	26627737	RPE1	viability after 12 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-0.5451999328724801	[294]	[81,24]	-4	hSpCas9	negative selection	1213466
63400069	63400092	18	-	26627737	RPE1	viability after 12 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.22516069942558864	[1099]	[297,204]	-1	hSpCas9	negative selection	1213467
63400652	63400675	18	-	26627737	RPE1	viability after 12 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.7556942059485985	[438]	[220,175]	5	hSpCas9	negative selection	1213468
63410289	63410312	18	-	26627737	RPE1	viability after 12 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-1.1476140308366913	[2495]	[308,295]	-7	hSpCas9	negative selection	1213469
63411532	63411555	18	-	26627737	RPE1	viability after 12 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	0.9188984765437154	[672]	[336,346]	6	hSpCas9	negative selection	1213470
63393464	63393487	18	+	26627737	RPE1	viability after 15 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	1.6133036858178464	[79]	[83,54]	8	hSpCas9	negative selection	1295780
63399251	63399274	18	+	26627737	RPE1	viability after 15 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.13910675393673833	[294]	[153,31]	0	hSpCas9	negative selection	1295781
63400069	63400092	18	-	26627737	RPE1	viability after 15 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.06294778015015873	[1099]	[406,245]	0	hSpCas9	negative selection	1295782
63400652	63400675	18	-	26627737	RPE1	viability after 15 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.586370999171739	[438]	[216,156]	3	hSpCas9	negative selection	1295783
63410289	63410312	18	-	26627737	RPE1	viability after 15 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-1.3582069671286805	[2495]	[420,134]	-7	hSpCas9	negative selection	1295784
63411532	63411555	18	-	26627737	RPE1	viability after 15 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	0.6710525192490175	[672]	[267,336]	4	hSpCas9	negative selection	1295785
63393464	63393487	18	+	26627737	RPE1	viability after 18 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	1.339870988948351	[79]	[58,49]	7	hSpCas9	negative selection	1378095
63399251	63399274	18	+	26627737	RPE1	viability after 18 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-1.2589522844168148	[294]	[40,24]	-7	hSpCas9	negative selection	1378096
63400069	63400092	18	-	26627737	RPE1	viability after 18 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.2198829515250314	[1099]	[309,195]	-1	hSpCas9	negative selection	1378097
63400652	63400675	18	-	26627737	RPE1	viability after 18 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.38771553583962176	[438]	[154,154]	2	hSpCas9	negative selection	1378098
63410289	63410312	18	-	26627737	RPE1	viability after 18 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-1.4205447602766907	[2495]	[342,153]	-7	hSpCas9	negative selection	1378099
63411532	63411555	18	-	26627737	RPE1	viability after 18 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	0.4151420474955865	[672]	[261,220]	2	hSpCas9	negative selection	1378100
63393464	63393487	18	+	26627737	HeLa	viability after 8 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	-0.16712154062885498	[238]	[132,49,102]	-1	hSpCas9	negative selection	1460410
63399251	63399274	18	+	26627737	HeLa	viability after 8 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	1.0083218157224114	[256]	[305,269,123]	7	hSpCas9	negative selection	1460411
63400069	63400092	18	-	26627737	HeLa	viability after 8 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.9070489414363871	[775]	[192,109,235]	-7	hSpCas9	negative selection	1460412
63400652	63400675	18	-	26627737	HeLa	viability after 8 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.01736899748749507	[436]	[317,138,150]	0	hSpCas9	negative selection	1460413
63410289	63410312	18	-	26627737	HeLa	viability after 8 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.383195471310585	[484]	[185,387,234]	3	hSpCas9	negative selection	1460414
63411532	63411555	18	-	26627737	HeLa	viability after 8 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	1.502508921896103	[298]	[389,431,293]	9	hSpCas9	negative selection	1460415
63393464	63393487	18	+	26627737	HeLa	viability after 12 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	0.7525413269694823	[238]	[60,214,214]	6	hSpCas9	negative selection	1542725
63399251	63399274	18	+	26627737	HeLa	viability after 12 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.845555341172616	[256]	[298,121,161]	6	hSpCas9	negative selection	1542726
63400069	63400092	18	-	26627737	HeLa	viability after 12 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.3531966647477872	[775]	[367,161,235]	-3	hSpCas9	negative selection	1542727
63400652	63400675	18	-	26627737	HeLa	viability after 12 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	-0.09060096044606716	[436]	[153,172,180]	0	hSpCas9	negative selection	1542728
63410289	63410312	18	-	26627737	HeLa	viability after 12 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.4412359488683067	[484]	[255,384,162]	4	hSpCas9	negative selection	1542729
63411532	63411555	18	-	26627737	HeLa	viability after 12 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	1.398186625231732	[298]	[201,329,440]	8	hSpCas9	negative selection	1542730
63393464	63393487	18	+	26627737	HeLa	viability after 15 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	-0.15009507095264574	[238]	[62,92,108]	-1	hSpCas9	negative selection	1625040
63399251	63399274	18	+	26627737	HeLa	viability after 15 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.5846822967420621	[256]	[218,80,170]	5	hSpCas9	negative selection	1625041
63400069	63400092	18	-	26627737	HeLa	viability after 15 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.5896745887664028	[775]	[249,123,258]	-5	hSpCas9	negative selection	1625042
63400652	63400675	18	-	26627737	HeLa	viability after 15 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.02306761149144862	[436]	[216,105,221]	0	hSpCas9	negative selection	1625043
63410289	63410312	18	-	26627737	HeLa	viability after 15 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.6121884325319091	[484]	[131,432,345]	5	hSpCas9	negative selection	1625044
63411532	63411555	18	-	26627737	HeLa	viability after 15 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	1.9011918086089588	[298]	[577,394,383]	9	hSpCas9	negative selection	1625045
63393464	63393487	18	+	26627737	HeLa	viability after 18 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	-0.16263492352215803	[238]	[39,77,108]	-1	hSpCas9	negative selection	1707355
63399251	63399274	18	+	26627737	HeLa	viability after 18 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.6127778405801138	[256]	[152,66,170]	5	hSpCas9	negative selection	1707356
63400069	63400092	18	-	26627737	HeLa	viability after 18 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.5696123042070591	[775]	[169,106,258]	-5	hSpCas9	negative selection	1707357
63400652	63400675	18	-	26627737	HeLa	viability after 18 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.052243514928599494	[436]	[154,84,221]	0	hSpCas9	negative selection	1707358
63410289	63410312	18	-	26627737	HeLa	viability after 18 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.612198833928495	[484]	[92,352,345]	5	hSpCas9	negative selection	1707359
63411532	63411555	18	-	26627737	HeLa	viability after 18 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	1.906929991294108	[298]	[396,319,383]	9	hSpCas9	negative selection	1707360
63393464	63393487	18	+	26627737	HCT116	viability after 6 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	2.050976644873203	[199]	[264,55]	8	hSpCas9	negative selection	1789670
63399251	63399274	18	+	26627737	HCT116	viability after 6 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	1.8888582912100804	[464]	[48,392]	8	hSpCas9	negative selection	1789671
63400069	63400092	18	-	26627737	HCT116	viability after 6 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-2.2543012029474188	[968]	[58,16]	-8	hSpCas9	negative selection	1789672
63400652	63400675	18	-	26627737	HCT116	viability after 6 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	-1.3834604226108242	[433]	[49,12]	-7	hSpCas9	negative selection	1789673
63410289	63410312	18	-	26627737	HCT116	viability after 6 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.5059531594923914	[2191]	[654,397]	3	hSpCas9	negative selection	1789674
63411532	63411555	18	-	26627737	HCT116	viability after 6 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-1.701307354579307	[1647]	[205,9]	-7	hSpCas9	negative selection	1789675
63393464	63393487	18	+	26627737	HCT116	viability after 8 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	0.7738680446348414	[173]	[170,161,158]	7	hSpCas9	negative selection	1871985
63399251	63399274	18	+	26627737	HCT116	viability after 8 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.04325637799522634	[290]	[196,112,185]	0	hSpCas9	negative selection	1871986
63400069	63400092	18	-	26627737	HCT116	viability after 8 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.2846359901552177	[405]	[292,260,263]	3	hSpCas9	negative selection	1871987
63400652	63400675	18	-	26627737	HCT116	viability after 8 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.2635535234759833	[287]	[207,187,175]	3	hSpCas9	negative selection	1871988
63410289	63410312	18	-	26627737	HCT116	viability after 8 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	1.0343434742382362	[360]	[412,370,437]	8	hSpCas9	negative selection	1871989
63411532	63411555	18	-	26627737	HCT116	viability after 8 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.1975450520426017	[485]	[270,257,172]	-2	hSpCas9	negative selection	1871990
63393464	63393487	18	+	26627737	HCT116	viability after 9 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	0.16845739390298897	[199]	[35,78]	1	hSpCas9	negative selection	1954300
63399251	63399274	18	+	26627737	HCT116	viability after 9 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.7841546836003706	[464]	[453,23]	5	hSpCas9	negative selection	1954301
63400069	63400092	18	-	26627737	HCT116	viability after 9 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.3492590208868353	[968]	[306,120]	-2	hSpCas9	negative selection	1954302
63400652	63400675	18	-	26627737	HCT116	viability after 9 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	-0.17132331527018752	[433]	[98,105]	-1	hSpCas9	negative selection	1954303
63410289	63410312	18	-	26627737	HCT116	viability after 9 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-0.9889558520970553	[2191]	[209,361]	-6	hSpCas9	negative selection	1954304
63411532	63411555	18	-	26627737	HCT116	viability after 9 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.1662373254315952	[1647]	[404,381]	-1	hSpCas9	negative selection	1954305
63393464	63393487	18	+	26627737	HCT116	viability after 12 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	0.9540854003229906	[173]	[166,244,121]	7	hSpCas9	negative selection	2036615
63399251	63399274	18	+	26627737	HCT116	viability after 12 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-0.5135634662348117	[290]	[104,83,131]	-5	hSpCas9	negative selection	2036616
63400069	63400092	18	-	26627737	HCT116	viability after 12 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.07118566383428232	[405]	[174,254,182]	0	hSpCas9	negative selection	2036617
63400652	63400675	18	-	26627737	HCT116	viability after 12 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	-0.08474880827168574	[287]	[93,124,212]	-1	hSpCas9	negative selection	2036618
63410289	63410312	18	-	26627737	HCT116	viability after 12 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.7935141194729352	[360]	[291,339,357]	7	hSpCas9	negative selection	2036619
63411532	63411555	18	-	26627737	HCT116	viability after 12 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.5934347821215517	[485]	[128,236,146]	-6	hSpCas9	negative selection	2036620
63393464	63393487	18	+	26627737	HCT116	viability after 15 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	0.8828719259892034	[173]	[279,227,57]	7	hSpCas9	negative selection	2118930
63399251	63399274	18	+	26627737	HCT116	viability after 15 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-0.10987814365500323	[290]	[193,90,183]	-1	hSpCas9	negative selection	2118931
63400069	63400092	18	-	26627737	HCT116	viability after 15 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.19358932651835625	[405]	[284,235,280]	2	hSpCas9	negative selection	2118932
63400652	63400675	18	-	26627737	HCT116	viability after 15 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.1604517291545463	[287]	[199,137,217]	1	hSpCas9	negative selection	2118933
63410289	63410312	18	-	26627737	HCT116	viability after 15 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	1.2903748161096391	[360]	[502,363,651]	8	hSpCas9	negative selection	2118934
63411532	63411555	18	-	26627737	HCT116	viability after 15 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.13614149765868788	[485]	[287,301,176]	-1	hSpCas9	negative selection	2118935
63393464	63393487	18	+	26627737	HCT116	viability after 18 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	0.8382894270770714	[173]	[234,125,88]	6	hSpCas9	negative selection	2201245
63399251	63399274	18	+	26627737	HCT116	viability after 18 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.02122867372117484	[290]	[155,139,131]	0	hSpCas9	negative selection	2201246
63400069	63400092	18	-	26627737	HCT116	viability after 18 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.19249532871753727	[405]	[115,284,269]	1	hSpCas9	negative selection	2201247
63400652	63400675	18	-	26627737	HCT116	viability after 18 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.09618585806443136	[287]	[118,113,218]	0	hSpCas9	negative selection	2201248
63410289	63410312	18	-	26627737	HCT116	viability after 18 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	1.4965299352921073	[360]	[352,526,599]	9	hSpCas9	negative selection	2201249
63411532	63411555	18	-	26627737	HCT116	viability after 18 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.10416439840230152	[485]	[255,226,169]	-1	hSpCas9	negative selection	2201250
63410403	63410426	18	+	24336569	HL60	viability	CTTTGCCCTGATACTTTGCTTGG	VPS4B	ENSG00000119541	1.167917302931576	[260]	[1240]	8	hSpCas9	negative selection	2305868
63410408	63410431	18	-	24336569	HL60	viability	TAAAGCCAAGCAAAGTATCAGGG	VPS4B	ENSG00000119541	-0.6337754134365243	[1255]	[1712]	-5	hSpCas9	negative selection	2305869
63410434	63410457	18	-	24336569	HL60	viability	CCTTTAATAGATGAAGCACAGGG	VPS4B	ENSG00000119541	0.2590143906302458	[679]	[1721]	2	hSpCas9	negative selection	2305870
63411494	63411517	18	+	24336569	HL60	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	0.04164004406042243	[594]	[1295]	0	hSpCas9	negative selection	2305871
63411531	63411554	18	-	24336569	HL60	viability	CAGCGCAAGAAGACAAGGCTGGG	VPS4B	ENSG00000119541	-0.38696664760314736	[1178]	[1907]	-3	hSpCas9	negative selection	2305872
63411536	63411559	18	-	24336569	HL60	viability	CAAAGCAGCGCAAGAAGACAAGG	VPS4B	ENSG00000119541	0.15202602959088207	[628]	[1478]	1	hSpCas9	negative selection	2305873
63411563	63411586	18	-	24336569	HL60	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.19907236306153597	[593]	[1442]	2	hSpCas9	negative selection	2305874
63422221	63422244	18	+	24336569	HL60	viability	GAGCAATGATACCTGGAGGTTGG	VPS4B	ENSG00000119541	-0.8199718596035082	[1247]	[1495]	-6	hSpCas9	negative selection	2305875
63422230	63422253	18	+	24336569	HL60	viability	TACCTGGAGGTTGGGCGAAGTGG	VPS4B	ENSG00000119541	0.014043230299727677	[525]	[1123]	0	hSpCas9	negative selection	2305876
63422239	63422262	18	+	24336569	HL60	viability	GTTGGGCGAAGTGGATGACATGG	VPS4B	ENSG00000119541	0.6050591277500599	[616]	[1985]	5	hSpCas9	negative selection	2305877
63410403	63410426	18	+	24336569	KBM7	viability	CTTTGCCCTGATACTTTGCTTGG	VPS4B	ENSG00000119541	0.5498422593493413	[279]	[1117]	5	hSpCas9	negative selection	2373045
63410408	63410431	18	-	24336569	KBM7	viability	TAAAGCCAAGCAAAGTATCAGGG	VPS4B	ENSG00000119541	-0.5242853700310092	[617]	[1171]	-4	hSpCas9	negative selection	2373046
63410434	63410457	18	-	24336569	KBM7	viability	CCTTTAATAGATGAAGCACAGGG	VPS4B	ENSG00000119541	0.06699397628087578	[545]	[1559]	0	hSpCas9	negative selection	2373047
63411494	63411517	18	+	24336569	KBM7	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	0.6198337248601347	[438]	[1839]	5	hSpCas9	negative selection	2373048
63411531	63411554	18	-	24336569	KBM7	viability	CAGCGCAAGAAGACAAGGCTGGG	VPS4B	ENSG00000119541	0.7916084673305437	[609]	[2879]	7	hSpCas9	negative selection	2373049
63411536	63411559	18	-	24336569	KBM7	viability	CAAAGCAGCGCAAGAAGACAAGG	VPS4B	ENSG00000119541	-0.12931741885928993	[787]	[1964]	-1	hSpCas9	negative selection	2373050
63411563	63411586	18	-	24336569	KBM7	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.6938657051975907	[431]	[1905]	6	hSpCas9	negative selection	2373051
63422221	63422244	18	+	24336569	KBM7	viability	GAGCAATGATACCTGGAGGTTGG	VPS4B	ENSG00000119541	0.12124360151702085	[808]	[2399]	1	hSpCas9	negative selection	2373052
63422230	63422253	18	+	24336569	KBM7	viability	TACCTGGAGGTTGGGCGAAGTGG	VPS4B	ENSG00000119541	0.20734586233984076	[160]	[506]	2	hSpCas9	negative selection	2373053
63422239	63422262	18	+	24336569	KBM7	viability	GTTGGGCGAAGTGGATGACATGG	VPS4B	ENSG00000119541	-0.7111002595102084	[592]	[987]	-5	hSpCas9	negative selection	2373054
63422218	63422241	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGATGAGCAATGATACCTGGAGG	VPS4B	ENSG00000119541	0.535546796551976	[3,3]	[2,5]	9	hSpCas9	positive selection	3031963
63400565	63400588	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCACTTAGAAACAAGATCAGAGG	VPS4B	ENSG00000119541	0.19454911153862625	[4,4]	[4,4]	4	hSpCas9	positive selection	3031964
63400564	63400587	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCTGATCTTGTTTCTAAGTGG	VPS4B	ENSG00000119541	0.28562077046048295	[5,5]	[5,6]	6	hSpCas9	positive selection	3031965
63410434	63410457	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTTAATAGATGAAGCACAGGG	VPS4B	ENSG00000119541	-0.2708550151343518	[3,3]	[4,0]	-4	hSpCas9	positive selection	3031966
63422218	63422241	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGATGAGCAATGATACCTGGAGG	VPS4B	ENSG00000119541	0.2627489554846434	[3,3]	[1,3]	4	hSpCas9	positive selection	3099821
63400565	63400588	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCACTTAGAAACAAGATCAGAGG	VPS4B	ENSG00000119541	0.16796243938154193	[4,4]	[5,2]	3	hSpCas9	positive selection	3099822
63400564	63400587	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCTGATCTTGTTTCTAAGTGG	VPS4B	ENSG00000119541	0.18461282375675514	[5,5]	[5,4]	3	hSpCas9	positive selection	3099823
63410434	63410457	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTTAATAGATGAAGCACAGGG	VPS4B	ENSG00000119541	-0.5871667527177262	[3,3]	[2,0]	-7	hSpCas9	positive selection	3099824
63411563	63411586		-	24336571	A375	resistance to PLX after 7 days	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.24438502337784151	[5,6]	[8,6]	7	hSpCas9	positive selection	3155134
63410308	63410331		+	24336571	A375	resistance to PLX after 7 days	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	-0.12388989180511001	[22,18]	[17,19]	-4	hSpCas9	positive selection	3155135
63411563	63411586		-	24336571	A375	resistance to PLX after 14 days	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.0247032856510494	[5,4]	[2,1]	0	hSpCas9	positive selection	3212927
63410308	63410331		+	24336571	A375	resistance to PLX after 14 days	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	-1.4060007664542766	[28,13]	[3,1]	-9	hSpCas9	positive selection	3212928
63411563	63411586		-	24336571	A375	viability after 7 days	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.6194143716525311	[10]	[5,6]	-7	hSpCas9	negative selection	3270720
63410308	63410331		+	24336571	A375	viability after 7 days	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.2517680518886321	[17]	[22,18]	4	hSpCas9	negative selection	3270721
63411563	63411586		-	24336571	A375	viability after 14 days	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.8433048954841862	[10]	[5,4]	-8	hSpCas9	negative selection	3328513
63410308	63410331		+	24336571	A375	viability after 14 days	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.2881073289353336	[17]	[28,13]	4	hSpCas9	negative selection	3328514
63411563	63411586	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	3.3504356158373163	[14,14]	[0,0]	9	hSpCas9	positive selection	3401027
63410284	63410307	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.2686415246736691	[380,380]	[2,2]	1	hSpCas9	positive selection	3401028
63411494	63411517	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.5628527509693527	[225,225]	[0,0]	-4	hSpCas9	positive selection	3401029
63422217	63422240	18	+	26780180	HT29	viability (Avana library 4 designs)	AGATGAGCAATGATACCTGGAGG	VPS4B	ENSG00000119541	2.11013788742878	[]	[]	7	hSpCas9	negative selection	3471197
63400564	63400587	18	+	26780180	HT29	viability (Avana library 4 designs)	CCACTTAGAAACAAGATCAGAGG	VPS4B	ENSG00000119541	0.843722439035989	[]	[]	3	hSpCas9	negative selection	3471198
63400564	63400587	18	-	26780180	HT29	viability (Avana library 4 designs)	CCTCTGATCTTGTTTCTAAGTGG	VPS4B	ENSG00000119541	0.00216767106349686	[]	[]	0	hSpCas9	negative selection	3471199
63410434	63410457	18	-	26780180	HT29	viability (Avana library 4 designs)	CCTTTAATAGATGAAGCACAGGG	VPS4B	ENSG00000119541	1.41543746347876	[]	[]	5	hSpCas9	negative selection	3471200
63410434	63410457	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTTAATAGATGAAGCACAGGG	VPS4B	ENSG00000119541	-12.9133039210679	[]	[]	-8	hSpCas9	negative selection	3577881
63422217	63422240	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGATGAGCAATGATACCTGGAGG	VPS4B	ENSG00000119541	1.72233493385631	[]	[]	2	hSpCas9	negative selection	3577882
63400564	63400587	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCTGATCTTGTTTCTAAGTGG	VPS4B	ENSG00000119541	-4.29709577106902	[]	[]	-5	hSpCas9	negative selection	3577883
63400564	63400587	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCACTTAGAAACAAGATCAGAGG	VPS4B	ENSG00000119541	-5.63893848608483	[]	[]	-6	hSpCas9	negative selection	3577884
63400643	63400666	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	0.798379500295505	[]	[]	1	hSpCas9	negative selection	3577885
63411495	63411518	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGCATGCTGATAGAGCTGAAGGG	VPS4B	ENSG00000119541	2.49645633986429	[]	[]	4	hSpCas9	negative selection	3577886
63410434	63410457	18	-	26780180	A375	viability (Avana lentiGuide)	CCTTTAATAGATGAAGCACAGGG	VPS4B	ENSG00000119541	-2.32690021142844	[]	[]	-4	hSpCas9	negative selection	3686540
63422217	63422240	18	+	26780180	A375	viability (Avana lentiGuide)	AGATGAGCAATGATACCTGGAGG	VPS4B	ENSG00000119541	3.53645936445271	[]	[]	3	hSpCas9	negative selection	3686541
63400564	63400587	18	-	26780180	A375	viability (Avana lentiGuide)	CCTCTGATCTTGTTTCTAAGTGG	VPS4B	ENSG00000119541	-1.666036078859	[]	[]	-3	hSpCas9	negative selection	3686542
63400564	63400587	18	+	26780180	A375	viability (Avana lentiGuide)	CCACTTAGAAACAAGATCAGAGG	VPS4B	ENSG00000119541	-3.71324394590067	[]	[]	-6	hSpCas9	negative selection	3686543
63400643	63400666	18	+	26780180	A375	viability (Avana lentiGuide)	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	12.2427606947865	[]	[]	7	hSpCas9	negative selection	3686544
63411495	63411518	18	+	26780180	A375	viability (Avana lentiGuide)	AGCATGCTGATAGAGCTGAAGGG	VPS4B	ENSG00000119541	-6.10939577938203	[]	[]	-9	hSpCas9	negative selection	3686545
63410434	63410457	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTTAATAGATGAAGCACAGGG	VPS4B	ENSG00000119541	-0.5461865111156098	[5]	[4,3]	-7	hSpCas9	positive selection	3795147
63422217	63422240	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATGAGCAATGATACCTGGAGG	VPS4B	ENSG00000119541	-0.07012766634198964	[5]	[5,3]	-1	hSpCas9	positive selection	3795148
63400564	63400587	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCTGATCTTGTTTCTAAGTGG	VPS4B	ENSG00000119541	-0.239632292247917	[8]	[6,6]	-4	hSpCas9	positive selection	3795149
63400564	63400587	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACTTAGAAACAAGATCAGAGG	VPS4B	ENSG00000119541	-0.09962916869712551	[6]	[5,6]	-2	hSpCas9	positive selection	3795150
63400643	63400666	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	0.16760442745038762	[5]	[5,5]	4	hSpCas9	positive selection	3795151
63411495	63411518	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCATGCTGATAGAGCTGAAGGG	VPS4B	ENSG00000119541	-0.041570749809973634	[5]	[4,4]	0	hSpCas9	positive selection	3795152
63410434	63410457	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTTAATAGATGAAGCACAGGG	VPS4B	ENSG00000119541	0.2896113236779837	[5]	[6,5]	7	hSpCas9	positive selection	3903754
63422217	63422240	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATGAGCAATGATACCTGGAGG	VPS4B	ENSG00000119541	-0.607938892777327	[5]	[2,3]	-6	hSpCas9	positive selection	3903755
63400564	63400587	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCTGATCTTGTTTCTAAGTGG	VPS4B	ENSG00000119541	0.16954494007064397	[7]	[7,7]	4	hSpCas9	positive selection	3903756
63400564	63400587	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACTTAGAAACAAGATCAGAGG	VPS4B	ENSG00000119541	0.22668346541068018	[6]	[6,6]	6	hSpCas9	positive selection	3903757
63400643	63400666	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	-0.033536481646150584	[5]	[5,3]	0	hSpCas9	positive selection	3903758
63411495	63411518	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCATGCTGATAGAGCTGAAGGG	VPS4B	ENSG00000119541	-0.36551111405468745	[4]	[2,2]	-5	hSpCas9	positive selection	3903759
63410284	63410307	18	+	26780180	A375	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	1.27350440427706	[]	[]	7	hSpCas9	negative selection	4011822
63400658	63400681	18	-	26780180	A375	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	1.35556111307121	[]	[]	7	hSpCas9	negative selection	4011823
63411563	63411586	18	-	26780180	A375	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.528266096055704	[]	[]	1	hSpCas9	negative selection	4011824
63411494	63411517	18	+	26780180	A375	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	1.12684519953582	[]	[]	5	hSpCas9	negative selection	4011825
63410308	63410331	18	+	26780180	A375	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.502437062025571	[]	[]	1	hSpCas9	negative selection	4011826
63400656	63400679	18	+	26780180	A375	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.811734828620019	[]	[]	3	hSpCas9	negative selection	4011827
63410284	63410307	18	+	26780180	HT29	viability (GeCKOv2 library)	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.875829602216163	[]	[]	3	hSpCas9	negative selection	4119788
63400658	63400681	18	-	26780180	HT29	viability (GeCKOv2 library)	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	1.45020735612693	[]	[]	7	hSpCas9	negative selection	4119789
63411563	63411586	18	-	26780180	HT29	viability (GeCKOv2 library)	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.67624200975622	[]	[]	2	hSpCas9	negative selection	4119790
63411494	63411517	18	+	26780180	HT29	viability (GeCKOv2 library)	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	1.27392806832878	[]	[]	6	hSpCas9	negative selection	4119791
63410308	63410331	18	+	26780180	HT29	viability (GeCKOv2 library)	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	-0.0762344960039835	[]	[]	-2	hSpCas9	negative selection	4119792
63400656	63400679	18	+	26780180	HT29	viability (GeCKOv2 library)	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	1.30164329763587	[]	[]	6	hSpCas9	negative selection	4119793
63411563	63411586	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.6577187569580519	[2]	[0,0]	-9	hSpCas9	positive selection	4181888
63410308	63410331	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	-0.2823545221262403	[4]	[3,1]	-6	hSpCas9	positive selection	4181889
63411563	63411586	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.6042199840399414	[3]	[3,5,1,0]	4	hSpCas9	positive selection	4245910
63410308	63410331	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	1.2892257088698398	[3]	[4,3,2,3]	9	hSpCas9	positive selection	4245911
63400658	63400681	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.26101003968218556	[3]	[3,2]	5	hSpCas9	positive selection	4307417
63400656	63400679	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.15774173895351623	[2]	[2,1]	3	hSpCas9	positive selection	4307418
63410308	63410331	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.1425943544037203	[4]	[4,2]	3	hSpCas9	positive selection	4307419
63411563	63411586	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.24826349042554086	[1]	[1,0]	5	hSpCas9	positive selection	4371665
63410284	63410307	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.14168223508940442	[4]	[3,3]	3	hSpCas9	positive selection	4371666
63411494	63411517	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.13247533680757112	[3]	[2,1]	-3	hSpCas9	positive selection	4371667
63397197	63397219	18	+	27760321	OCIAML3	viability	AACATTGCTGCTCGGGCATGGG	VPS4B	ENSG00000119541	0.3678717567492308	[958,735]	[732,999]	4	hSpCas9	negative selection	4453469
63400069	63400091	18	-	27760321	OCIAML3	viability	GCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.03823251187936538	[229,130]	[139,144]	0	hSpCas9	negative selection	4453470
63400658	63400680	18	-	27760321	OCIAML3	viability	TCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	1.9983805889204085	[28,30]	[69,125]	9	hSpCas9	negative selection	4453471
63403802	63403824	18	+	27760321	OCIAML3	viability	TTTGGTCGTTCTATAACAATGG	VPS4B	ENSG00000119541	-4.407686756732138	[32,21]	[0,0]	-9	hSpCas9	negative selection	4453472
63410435	63410457	18	-	27760321	OCIAML3	viability	CCTTTAATAGATGAAGCACAGG	VPS4B	ENSG00000119541	0.5209400900456895	[176,134]	[151,201]	6	hSpCas9	negative selection	4453473
63397197	63397219	18	+	27760321	OCIAML2	viability	AACATTGCTGCTCGGGCATGGG	VPS4B	ENSG00000119541	0.10877480395670547	[958,735]	[564,955]	1	hSpCas9	negative selection	4536932
63400069	63400091	18	-	27760321	OCIAML2	viability	GCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.11073067690801341	[229,130]	[82,248]	1	hSpCas9	negative selection	4536933
63400658	63400680	18	-	27760321	OCIAML2	viability	TCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	1.2685782564794428	[28,30]	[63,51]	9	hSpCas9	negative selection	4536934
63403802	63403824	18	+	27760321	OCIAML2	viability	TTTGGTCGTTCTATAACAATGG	VPS4B	ENSG00000119541	0.9217053098289774	[32,21]	[38,44]	9	hSpCas9	negative selection	4536935
63410435	63410457	18	-	27760321	OCIAML2	viability	CCTTTAATAGATGAAGCACAGG	VPS4B	ENSG00000119541	-0.5712863929444525	[176,134]	[85,81]	-6	hSpCas9	negative selection	4536936
63397197	63397219	18	+	27760321	MV411	viability	AACATTGCTGCTCGGGCATGGG	VPS4B	ENSG00000119541	0.6045068471484213	[958,735]	[783,933]	4	hSpCas9	negative selection	4620395
63400069	63400091	18	-	27760321	MV411	viability	GCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-2.4753940481265024	[229,130]	[28,8]	-9	hSpCas9	negative selection	4620396
63400658	63400680	18	-	27760321	MV411	viability	TCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	-0.37088863398624605	[28,30]	[16,12]	-3	hSpCas9	negative selection	4620397
63403802	63403824	18	+	27760321	MV411	viability	TTTGGTCGTTCTATAACAATGG	VPS4B	ENSG00000119541	-1.4411575329123298	[32,21]	[0,14]	-7	hSpCas9	negative selection	4620398
63410435	63410457	18	-	27760321	MV411	viability	CCTTTAATAGATGAAGCACAGG	VPS4B	ENSG00000119541	0.13486446735853175	[176,134]	[56,194]	0	hSpCas9	negative selection	4620399
63397197	63397219	18	+	27760321	HL60	viability	AACATTGCTGCTCGGGCATGGG	VPS4B	ENSG00000119541	-0.45363978186279297	[958,735]	[508,493]	-5	hSpCas9	negative selection	4703858
63400069	63400091	18	-	27760321	HL60	viability	GCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.2610204996861998	[229,130]	[109,131]	-3	hSpCas9	negative selection	4703859
63400658	63400680	18	-	27760321	HL60	viability	TCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	-0.653088069111655	[28,30]	[4,26]	-6	hSpCas9	negative selection	4703860
63403802	63403824	18	+	27760321	HL60	viability	TTTGGTCGTTCTATAACAATGG	VPS4B	ENSG00000119541	-1.7798228110216066	[32,21]	[4,7]	-9	hSpCas9	negative selection	4703861
63410435	63410457	18	-	27760321	HL60	viability	CCTTTAATAGATGAAGCACAGG	VPS4B	ENSG00000119541	-0.1561431534694544	[176,134]	[95,131]	-2	hSpCas9	negative selection	4703862
63397197	63397219	18	+	27760321	HT1080	viability	AACATTGCTGCTCGGGCATGGG	VPS4B	ENSG00000119541	1.9775743412345799	[735,574]	[1417,601]	9	hSpCas9	negative selection	4787321
63400069	63400091	18	-	27760321	HT1080	viability	GCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.16421125637623923	[130,101]	[28,54]	-1	hSpCas9	negative selection	4787322
63400658	63400680	18	-	27760321	HT1080	viability	TCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	-0.6981212579135896	[30,23]	[11,0]	-3	hSpCas9	negative selection	4787323
63403802	63403824	18	+	27760321	HT1080	viability	TTTGGTCGTTCTATAACAATGG	VPS4B	ENSG00000119541	2.8918070990165337	[21,16]	[17,100]	9	hSpCas9	negative selection	4787324
63410435	63410457	18	-	27760321	HT1080	viability	CCTTTAATAGATGAAGCACAGG	VPS4B	ENSG00000119541	0.5659050637639051	[134,105]	[93,45]	3	hSpCas9	negative selection	4787325
63397197	63397219	18	+	27760321	HT29	viability after 7 days	AACATTGCTGCTCGGGCATGGG	VPS4B	ENSG00000119541	0.11964307982957179	[735,574]	[1046,1070,654]	1	hSpCas9	negative selection	4870784
63400069	63400091	18	-	27760321	HT29	viability after 7 days	GCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.5215356475961714	[130,101]	[202,258,181]	7	hSpCas9	negative selection	4870785
63400658	63400680	18	-	27760321	HT29	viability after 7 days	TCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	-0.7698715697466101	[30,23]	[2,47,8]	-8	hSpCas9	negative selection	4870786
63403802	63403824	18	+	27760321	HT29	viability after 7 days	TTTGGTCGTTCTATAACAATGG	VPS4B	ENSG00000119541	-0.7295950010665377	[21,16]	[9,0,32]	-7	hSpCas9	negative selection	4870787
63410435	63410457	18	-	27760321	HT29	viability after 7 days	CCTTTAATAGATGAAGCACAGG	VPS4B	ENSG00000119541	-0.11123383733320824	[134,105]	[239,91,112]	-2	hSpCas9	negative selection	4870788
63397197	63397219	18	+	27760321	HT29	viability after 25 days	AACATTGCTGCTCGGGCATGGG	VPS4B	ENSG00000119541	-0.2913406366440531	[735,574]	[604,739,476]	-3	hSpCas9	negative selection	4954247
63400069	63400091	18	-	27760321	HT29	viability after 25 days	GCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.28432927343433567	[130,101]	[49,204,246]	3	hSpCas9	negative selection	4954248
63400658	63400680	18	-	27760321	HT29	viability after 25 days	TCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	-0.19823108237608356	[30,23]	[25,38,15]	-2	hSpCas9	negative selection	4954249
63403802	63403824	18	+	27760321	HT29	viability after 25 days	TTTGGTCGTTCTATAACAATGG	VPS4B	ENSG00000119541	-0.34247214770638656	[21,16]	[3,1,50]	-3	hSpCas9	negative selection	4954250
63410435	63410457	18	-	27760321	HT29	viability after 25 days	CCTTTAATAGATGAAGCACAGG	VPS4B	ENSG00000119541	-0.05789144577100447	[134,105]	[115,199,75]	0	hSpCas9	negative selection	4954251
63397197	63397219	18	+	27760321	HT29	viability after 22 days	AACATTGCTGCTCGGGCATGGG	VPS4B	ENSG00000119541	0.15917503434696256	[735,574]	[1099,984,442]	1	hSpCas9	negative selection	5037710
63400069	63400091	18	-	27760321	HT29	viability after 22 days	GCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.4774265730893965	[130,101]	[95,271,196]	5	hSpCas9	negative selection	5037711
63400658	63400680	18	-	27760321	HT29	viability after 22 days	TCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.3246169972398265	[30,23]	[25,27,65]	3	hSpCas9	negative selection	5037712
63403802	63403824	18	+	27760321	HT29	viability after 22 days	TTTGGTCGTTCTATAACAATGG	VPS4B	ENSG00000119541	-0.9248226443340872	[21,16]	[0,11,22]	-6	hSpCas9	negative selection	5037713
63410435	63410457	18	-	27760321	HT29	viability after 22 days	CCTTTAATAGATGAAGCACAGG	VPS4B	ENSG00000119541	-1.1979309270393947	[134,105]	[59,87,33]	-7	hSpCas9	negative selection	5037714
63397197	63397219	18	+	27760321	HT29	viability after 19 days	AACATTGCTGCTCGGGCATGGG	VPS4B	ENSG00000119541	0.19842027841464704	[735,574]	[1001,918,680]	1	hSpCas9	negative selection	5121173
63400069	63400091	18	-	27760321	HT29	viability after 19 days	GCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.8350447007134439	[130,101]	[259,79,369]	8	hSpCas9	negative selection	5121174
63400658	63400680	18	-	27760321	HT29	viability after 19 days	TCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	-0.01777082506968064	[30,23]	[57,34,3]	0	hSpCas9	negative selection	5121175
63403802	63403824	18	+	27760321	HT29	viability after 19 days	TTTGGTCGTTCTATAACAATGG	VPS4B	ENSG00000119541	-2.65453981262774	[21,16]	[6,0,2]	-8	hSpCas9	negative selection	5121176
63410435	63410457	18	-	27760321	HT29	viability after 19 days	CCTTTAATAGATGAAGCACAGG	VPS4B	ENSG00000119541	-0.7458329838427822	[134,105]	[97,34,113]	-5	hSpCas9	negative selection	5121177
63397197	63397219	18	+	27760321	HT29	viability after 16 days	AACATTGCTGCTCGGGCATGGG	VPS4B	ENSG00000119541	-0.019735847431216813	[735,574]	[743,730,696]	0	hSpCas9	negative selection	5204636
63400069	63400091	18	-	27760321	HT29	viability after 16 days	GCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.6607102371183586	[130,101]	[148,153,310]	7	hSpCas9	negative selection	5204637
63400658	63400680	18	-	27760321	HT29	viability after 16 days	TCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.6936751514212269	[30,23]	[84,31,35]	7	hSpCas9	negative selection	5204638
63403802	63403824	18	+	27760321	HT29	viability after 16 days	TTTGGTCGTTCTATAACAATGG	VPS4B	ENSG00000119541	0.7440706854556147	[21,16]	[21,4,81]	8	hSpCas9	negative selection	5204639
63410435	63410457	18	-	27760321	HT29	viability after 16 days	CCTTTAATAGATGAAGCACAGG	VPS4B	ENSG00000119541	-0.4377799060685976	[134,105]	[184,51,70]	-4	hSpCas9	negative selection	5204640
63397197	63397219	18	+	27760321	HT29	viability after 13 days	AACATTGCTGCTCGGGCATGGG	VPS4B	ENSG00000119541	0.03033083936946146	[735,574]	[739,848,742]	0	hSpCas9	negative selection	5288099
63400069	63400091	18	-	27760321	HT29	viability after 13 days	GCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.7583493325647136	[130,101]	[96,308,276]	8	hSpCas9	negative selection	5288100
63400658	63400680	18	-	27760321	HT29	viability after 13 days	TCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	-0.15924623016054706	[30,23]	[3,57,23]	-2	hSpCas9	negative selection	5288101
63403802	63403824	18	+	27760321	HT29	viability after 13 days	TTTGGTCGTTCTATAACAATGG	VPS4B	ENSG00000119541	0.5462367315757293	[21,16]	[73,9,15]	7	hSpCas9	negative selection	5288102
63410435	63410457	18	-	27760321	HT29	viability after 13 days	CCTTTAATAGATGAAGCACAGG	VPS4B	ENSG00000119541	-0.4486127421562942	[134,105]	[172,78,57]	-5	hSpCas9	negative selection	5288103
63397197	63397219	18	+	27760321	HT29	viability after 10 days	AACATTGCTGCTCGGGCATGGG	VPS4B	ENSG00000119541	-0.22155512159195334	[735,574]	[493,939,678]	-3	hSpCas9	negative selection	5371562
63400069	63400091	18	-	27760321	HT29	viability after 10 days	GCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.27592616320635255	[130,101]	[100,244,183]	3	hSpCas9	negative selection	5371563
63400658	63400680	18	-	27760321	HT29	viability after 10 days	TCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	-0.3702953058095728	[30,23]	[27,12,37]	-5	hSpCas9	negative selection	5371564
63403802	63403824	18	+	27760321	HT29	viability after 10 days	TTTGGTCGTTCTATAACAATGG	VPS4B	ENSG00000119541	-0.29499833939250486	[21,16]	[12,12,32]	-4	hSpCas9	negative selection	5371565
63410435	63410457	18	-	27760321	HT29	viability after 10 days	CCTTTAATAGATGAAGCACAGG	VPS4B	ENSG00000119541	-0.5174730957608855	[134,105]	[209,69,35]	-6	hSpCas9	negative selection	5371566
63397197	63397219	18	+	27760321	MOLM13	viability	AACATTGCTGCTCGGGCATGGG	VPS4B	ENSG00000119541	-0.049761020181606885	[958,735]	[552,377]	0	hSpCas9	negative selection	5455025
63400069	63400091	18	-	27760321	MOLM13	viability	GCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-1.1604000148152713	[229,130]	[95,0]	-6	hSpCas9	negative selection	5455026
63400658	63400680	18	-	27760321	MOLM13	viability	TCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	-2.8391451371207475	[28,30]	[3,0]	-8	hSpCas9	negative selection	5455027
63403802	63403824	18	+	27760321	MOLM13	viability	TTTGGTCGTTCTATAACAATGG	VPS4B	ENSG00000119541	1.7305245334594517	[32,21]	[12,82]	9	hSpCas9	negative selection	5455028
63410435	63410457	18	-	27760321	MOLM13	viability	CCTTTAATAGATGAAGCACAGG	VPS4B	ENSG00000119541	0.4638692493293297	[176,134]	[221,33]	3	hSpCas9	negative selection	5455029
63422392	63422415	18	-	27661255	K562	viability	GTCTAAAACAAGTTCCGGAAGGG	VPS4B	ENSG00000119541	-0.09057936249116638	[455,582]	[414,364]	-3	dCas9-KRAB	negative selection	5522336
63422425	63422448	18	-	27661255	K562	viability	GGGGAGGGTCGGAGCTCTGGTGG	VPS4B	ENSG00000119541	-0.036881504667301	[178,210]	[206,103]	-1	dCas9-KRAB	negative selection	5522337
63422428	63422451	18	-	27661255	K562	viability	GGTGGGGAGGGTCGGAGCTCTGG	VPS4B	ENSG00000119541	-0.057138184658985125	[619,610]	[584,376]	-2	dCas9-KRAB	negative selection	5522338
63422444	63422467	18	-	27661255	K562	viability	GGGATTGCGGAAGTTTGGTGGGG	VPS4B	ENSG00000119541	0.08567090232339852	[592,611]	[578,451]	3	dCas9-KRAB	negative selection	5522339
63400658	63400681	18	-	27260156	BXPC3	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.2093663349170426	[725]	[783,745,1067,934]	4	hSpCas9	negative selection	5579877
63400656	63400679	18	+	27260156	BXPC3	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.06612171438116132	[224]	[210,234,286,256]	1	hSpCas9	negative selection	5579878
63410308	63410331	18	+	27260156	BXPC3	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.3885468457397483	[1214]	[1665,1566,1685,1735]	8	hSpCas9	negative selection	5579879
63411563	63411586	18	-	27260156	BXPC3	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.5735254677597621	[81]	[65,40,75,45]	-8	hSpCas9	negative selection	5644125
63410284	63410307	18	+	27260156	BXPC3	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.03951594624187238	[1100]	[1062,1074,1159,1192]	-1	hSpCas9	negative selection	5644126
63411494	63411517	18	+	27260156	BXPC3	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.1538897041116168	[550]	[563,403,522,586]	-4	hSpCas9	negative selection	5644127
63400658	63400681	18	-	27260156	A673	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.15574096449415475	[725]	[1183,869,891,963]	4	hSpCas9	negative selection	5701128
63400656	63400679	18	+	27260156	A673	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.009014121578207357	[224]	[364,213,209,312]	0	hSpCas9	negative selection	5701129
63410308	63410331	18	+	27260156	A673	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.5344540349370097	[1214]	[2456,1940,1913,2185]	9	hSpCas9	negative selection	5701130
63411563	63411586	18	-	27260156	A673	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.05163693934246849	[81]	[76,74,85,142]	-1	hSpCas9	negative selection	5765376
63410284	63410307	18	+	27260156	A673	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.07901828889439755	[1100]	[1395,1159,1084,1390]	-2	hSpCas9	negative selection	5765377
63411494	63411517	18	+	27260156	A673	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	0.1172127257980616	[550]	[627,661,673,906]	3	hSpCas9	negative selection	5765378
63400658	63400681	18	-	27260156	A375	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.5377037534593034	[725]	[1184,1487,1129,1159]	7	hSpCas9	negative selection	5822379
63400656	63400679	18	+	27260156	A375	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.3095818558191715	[224]	[248,271,432,337]	4	hSpCas9	negative selection	5822380
63410308	63410331	18	+	27260156	A375	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.5839222732915768	[1214]	[2242,2499,1840,1985]	8	hSpCas9	negative selection	5822381
63411563	63411586	18	-	27260156	A375	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.28322580194011726	[81]	[58,31,46,159]	-4	hSpCas9	negative selection	5886627
63410284	63410307	18	+	27260156	A375	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.06095872151766879	[1100]	[1527,1470,1057,939]	-1	hSpCas9	negative selection	5886628
63411494	63411517	18	+	27260156	A375	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.0022293926274228604	[550]	[743,783,489,577]	0	hSpCas9	negative selection	5886629
63400658	63400681	18	-	27260156	COLO741	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.32636257037119787	[725]	[1165,1019,1290]	6	hSpCas9	negative selection	5943630
63400656	63400679	18	+	27260156	COLO741	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.15986670519908586	[224]	[319,269,368]	3	hSpCas9	negative selection	5943631
63410308	63410331	18	+	27260156	COLO741	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.4479758184408764	[1214]	[2156,2305,1904]	8	hSpCas9	negative selection	5943632
63411563	63411586	18	-	27260156	COLO741	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.826907510656095	[81]	[75,36,64]	-9	hSpCas9	negative selection	6007878
63410284	63410307	18	+	27260156	COLO741	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.07933629619236782	[1100]	[1473,1263,1269]	-2	hSpCas9	negative selection	6007879
63411494	63411517	18	+	27260156	COLO741	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.4505144615826392	[550]	[409,544,575]	-7	hSpCas9	negative selection	6007880
63400658	63400681	18	-	27260156	CAL120	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.5526713795293803	[725]	[1514,1417,1074]	7	hSpCas9	negative selection	6064881
63400656	63400679	18	+	27260156	CAL120	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.7637748272317312	[224]	[506,629,296]	9	hSpCas9	negative selection	6064882
63410308	63410331	18	+	27260156	CAL120	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.5744481508919079	[1214]	[2262,2123,2365]	8	hSpCas9	negative selection	6064883
63411563	63411586	18	-	27260156	CAL120	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.5775071354181711	[81]	[52,36,111]	-7	hSpCas9	negative selection	6129129
63410284	63410307	18	+	27260156	CAL120	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.03606803757299515	[1100]	[1138,1646,1387]	0	hSpCas9	negative selection	6129130
63411494	63411517	18	+	27260156	CAL120	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	0.21790622400450335	[550]	[927,816,668]	3	hSpCas9	negative selection	6129131
63400658	63400681	18	-	27260156	CADOES1	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.36143608089857726	[725]	[893,863,863,846]	6	hSpCas9	negative selection	6186132
63400656	63400679	18	+	27260156	CADOES1	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.08454716208343771	[224]	[289,179,228,186]	1	hSpCas9	negative selection	6186133
63410308	63410331	18	+	27260156	CADOES1	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.579053434642778	[1214]	[1655,1450,1725,1927]	8	hSpCas9	negative selection	6186134
63411563	63411586	18	-	27260156	CADOES1	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.0994454599001533	[81]	[96,76,90,60]	1	hSpCas9	negative selection	6250380
63410284	63410307	18	+	27260156	CADOES1	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.06099707947749744	[1100]	[1133,984,877,926]	-1	hSpCas9	negative selection	6250381
63411494	63411517	18	+	27260156	CADOES1	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.17310518052731005	[550]	[461,438,513,400]	-3	hSpCas9	negative selection	6250382
63400658	63400681	18	-	27260156	EWS502	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.47602792257792714	[725]	[1234,1129,828,1052]	8	hSpCas9	negative selection	6307383
63400656	63400679	18	+	27260156	EWS502	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	-0.09316667634519171	[224]	[270,152,244,220]	-2	hSpCas9	negative selection	6307384
63410308	63410331	18	+	27260156	EWS502	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.5804314731915157	[1214]	[1916,2000,1897,1866]	8	hSpCas9	negative selection	6307385
63411563	63411586	18	-	27260156	EWS502	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.9393595292146406	[81]	[27,79,18,54]	-8	hSpCas9	negative selection	6371631
63410284	63410307	18	+	27260156	EWS502	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.07206751250256516	[1100]	[1269,1059,1134,1449]	1	hSpCas9	negative selection	6371632
63411494	63411517	18	+	27260156	EWS502	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.3195996279070306	[550]	[529,397,532,398]	-5	hSpCas9	negative selection	6371633
63400658	63400681	18	-	27260156	EW8	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.19738540746619082	[725]	[908,661,415,778]	3	hSpCas9	negative selection	6428634
63400656	63400679	18	+	27260156	EW8	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	-0.3160778174863774	[224]	[171,115,158,138]	-5	hSpCas9	negative selection	6428635
63410308	63410331	18	+	27260156	EW8	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.6637011236191475	[1214]	[1682,1497,1374,1722]	9	hSpCas9	negative selection	6428636
63411563	63411586	18	-	27260156	EW8	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.28587170461952693	[81]	[10,112,50,38]	-5	hSpCas9	negative selection	6492882
63410284	63410307	18	+	27260156	EW8	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.09759403649759446	[1100]	[977,734,759,887]	-2	hSpCas9	negative selection	6492883
63411494	63411517	18	+	27260156	EW8	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.22244006776426206	[550]	[509,363,304,377]	-4	hSpCas9	negative selection	6492884
63400658	63400681	18	-	27260156	CORL105	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.3538766178529137	[725]	[1088,1058,1161,1046]	6	hSpCas9	negative selection	6549885
63400656	63400679	18	+	27260156	CORL105	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.17756173575027578	[224]	[299,263,340,293]	3	hSpCas9	negative selection	6549886
63410308	63410331	18	+	27260156	CORL105	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.37713900029209513	[1214]	[1589,1841,2141,1851]	7	hSpCas9	negative selection	6549887
63411563	63411586	18	-	27260156	CORL105	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-1.0110233999744027	[81]	[22,87,22,50]	-9	hSpCas9	negative selection	6614133
63410284	63410307	18	+	27260156	CORL105	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.005779375274303389	[1100]	[1111,1125,1480,1442]	0	hSpCas9	negative selection	6614134
63411494	63411517	18	+	27260156	CORL105	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.1982848073468307	[550]	[610,518,610,517]	-4	hSpCas9	negative selection	6614135
63400658	63400681	18	-	27260156	HS294T	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.012627842164634862	[725]	[249,368,219,294]	0	hSpCas9	negative selection	6671136
63400656	63400679	18	+	27260156	HS294T	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.2758542026288128	[224]	[133,88,73,124]	4	hSpCas9	negative selection	6671137
63410308	63410331	18	+	27260156	HS294T	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.33353888843064694	[1214]	[661,530,491,692]	4	hSpCas9	negative selection	6671138
63411563	63411586	18	-	27260156	HS294T	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.47805863694669704	[81]	[26,15,23,23]	-6	hSpCas9	negative selection	6735384
63410284	63410307	18	+	27260156	HS294T	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.19851305901183913	[1100]	[489,525,420,518]	2	hSpCas9	negative selection	6735385
63411494	63411517	18	+	27260156	HS294T	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	0.470872708296596	[550]	[317,347,279,216]	6	hSpCas9	negative selection	6735386
63400658	63400681	18	-	27260156	HCC44	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.051686236698320176	[725]	[922,845,857,780]	0	hSpCas9	negative selection	6792387
63400656	63400679	18	+	27260156	HCC44	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.3067883355933718	[224]	[452,106,438,320]	5	hSpCas9	negative selection	6792388
63410308	63410331	18	+	27260156	HCC44	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.5544995693139836	[1214]	[2245,1469,2574,1961]	8	hSpCas9	negative selection	6792389
63411563	63411586	18	-	27260156	HCC44	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.7927310339417297	[81]	[30,97,21,48]	-8	hSpCas9	negative selection	6856635
63410284	63410307	18	+	27260156	HCC44	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.14845597627257745	[1100]	[1444,1146,1579,1409]	2	hSpCas9	negative selection	6856636
63411494	63411517	18	+	27260156	HCC44	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.11367716189287527	[550]	[599,410,848,513]	-2	hSpCas9	negative selection	6856637
63400658	63400681	18	-	27260156	G402	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.40891683916693466	[725]	[1361,1140,1366,869]	5	hSpCas9	negative selection	6913638
63400656	63400679	18	+	27260156	G402	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.09870785721155062	[224]	[293,306,416,163]	1	hSpCas9	negative selection	6913639
63410308	63410331	18	+	27260156	G402	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.7025829139074333	[1214]	[2362,1534,2778,2882]	8	hSpCas9	negative selection	6913640
63411563	63411586	18	-	27260156	G402	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-1.0839100457556872	[81]	[30,41,44,66]	-8	hSpCas9	negative selection	6977886
63410284	63410307	18	+	27260156	G402	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.1116108710191781	[1100]	[1238,1984,1343,1242]	1	hSpCas9	negative selection	6977887
63411494	63411517	18	+	27260156	G402	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.19116329287679634	[550]	[608,707,581,469]	-2	hSpCas9	negative selection	6977888
63400658	63400681	18	-	27260156	L33	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.03709612574548726	[725]	[774,271,451,819]	0	hSpCas9	negative selection	7034889
63400656	63400679	18	+	27260156	L33	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.981865609313741	[224]	[319,63,191,992]	9	hSpCas9	negative selection	7034890
63410308	63410331	18	+	27260156	L33	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.2444454812838659	[1214]	[1422,652,887,1328]	5	hSpCas9	negative selection	7034891
63411563	63411586	18	-	27260156	L33	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.18381072690271738	[81]	[43,76,13,118]	4	hSpCas9	negative selection	7099137
63410284	63410307	18	+	27260156	L33	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.1097278805316686	[1100]	[980,394,699,1023]	-2	hSpCas9	negative selection	7099138
63411494	63411517	18	+	27260156	L33	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.045909060226172554	[550]	[561,171,314,649]	-1	hSpCas9	negative selection	7099139
63400658	63400681	18	-	27260156	K562	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.34312741620257525	[725]	[877,753,1032,624]	4	hSpCas9	negative selection	7156140
63400656	63400679	18	+	27260156	K562	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.3781371866910186	[224]	[238,405,157,241]	5	hSpCas9	negative selection	7156141
63410308	63410331	18	+	27260156	K562	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.8452753483538973	[1214]	[2820,1936,1318,1756]	9	hSpCas9	negative selection	7156142
63411563	63411586	18	-	27260156	K562	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.3469347666311142	[81]	[91,38,190,49]	4	hSpCas9	negative selection	7220388
63410284	63410307	18	+	27260156	K562	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.21962982100347417	[1100]	[1321,1274,1207,802]	2	hSpCas9	negative selection	7220389
63411494	63411517	18	+	27260156	K562	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	0.8273415859235573	[550]	[1479,627,1024,423]	9	hSpCas9	negative selection	7220390
63400658	63400681	18	-	27260156	HT29	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.2174868870902732	[725]	[1220,1080,1185,672]	4	hSpCas9	negative selection	7277391
63400656	63400679	18	+	27260156	HT29	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	-0.23525001785579058	[224]	[286,201,204,234]	-5	hSpCas9	negative selection	7277392
63410308	63410331	18	+	27260156	HT29	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.5978517761855204	[1214]	[2435,2457,2291,1824]	9	hSpCas9	negative selection	7277393
63411563	63411586	18	-	27260156	HT29	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.6374722155438488	[81]	[87,68,62,40]	-8	hSpCas9	negative selection	7341639
63410284	63410307	18	+	27260156	HT29	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.06475856441298689	[1100]	[1260,1136,1421,1275]	-1	hSpCas9	negative selection	7341640
63411494	63411517	18	+	27260156	HT29	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.2568713046960934	[550]	[603,611,577,463]	-5	hSpCas9	negative selection	7341641
63400658	63400681	18	-	27260156	MHHES1	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.19963157238231033	[725]	[791,1064,947,926]	3	hSpCas9	negative selection	7398642
63400656	63400679	18	+	27260156	MHHES1	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	-0.1901234147095039	[224]	[258,299,184,164]	-4	hSpCas9	negative selection	7398643
63410308	63410331	18	+	27260156	MHHES1	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.5247609476241208	[1214]	[2438,1913,1750,1811]	8	hSpCas9	negative selection	7398644
63411563	63411586	18	-	27260156	MHHES1	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.08743408778436379	[81]	[162,128,52,63]	1	hSpCas9	negative selection	7462890
63410284	63410307	18	+	27260156	MHHES1	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.03600953044842492	[1100]	[1868,1227,1246,873]	0	hSpCas9	negative selection	7462891
63411494	63411517	18	+	27260156	MHHES1	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.1998436508845857	[550]	[656,634,510,401]	-4	hSpCas9	negative selection	7462892
63400658	63400681	18	-	27260156	MEWO	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.003460314512449658	[725]	[743,604,705]	0	hSpCas9	negative selection	7519893
63400656	63400679	18	+	27260156	MEWO	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.07385887557460724	[224]	[156,245,248]	1	hSpCas9	negative selection	7519894
63410308	63410331	18	+	27260156	MEWO	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.42832339828185284	[1214]	[1836,1345,1465]	8	hSpCas9	negative selection	7519895
63411563	63411586	18	-	27260156	MEWO	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.11794865987795333	[81]	[106,90,20]	-3	hSpCas9	negative selection	7584141
63410284	63410307	18	+	27260156	MEWO	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.08025713498450204	[1100]	[1417,973,938]	1	hSpCas9	negative selection	7584142
63411494	63411517	18	+	27260156	MEWO	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	0.02324028118146651	[550]	[480,559,521]	0	hSpCas9	negative selection	7584143
63400658	63400681	18	-	27260156	LNCAPCLONEFGC	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.5215276322277365	[725]	[763,1035,1240,775]	7	hSpCas9	negative selection	7641144
63400656	63400679	18	+	27260156	LNCAPCLONEFGC	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.2572851224736151	[224]	[214,217,320,233]	4	hSpCas9	negative selection	7641145
63410308	63410331	18	+	27260156	LNCAPCLONEFGC	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.5721918661673284	[1214]	[1604,1501,1643,1803]	8	hSpCas9	negative selection	7641146
63411563	63411586	18	-	27260156	LNCAPCLONEFGC	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.054487088071920375	[81]	[44,48,124,76]	-1	hSpCas9	negative selection	7705392
63410284	63410307	18	+	27260156	LNCAPCLONEFGC	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.035585264559601315	[1100]	[862,836,1008,1198]	0	hSpCas9	negative selection	7705393
63411494	63411517	18	+	27260156	LNCAPCLONEFGC	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.050223645986823384	[550]	[504,385,523,524]	-1	hSpCas9	negative selection	7705394
63400658	63400681	18	-	27260156	PANC0327	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	-0.003528455778216366	[725]	[1098,660,420,426]	0	hSpCas9	negative selection	7762395
63400656	63400679	18	+	27260156	PANC0327	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.346081252263266	[224]	[165,138,408,309]	5	hSpCas9	negative selection	7762396
63410308	63410331	18	+	27260156	PANC0327	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.18372412855081444	[1214]	[1359,1110,1244,1212]	2	hSpCas9	negative selection	7762397
63411563	63411586	18	-	27260156	PANC0327	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-1.365632432776016	[81]	[2,43,47,13]	-9	hSpCas9	negative selection	7826643
63410284	63410307	18	+	27260156	PANC0327	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.042535499230357265	[1100]	[1022,659,1119,1271]	0	hSpCas9	negative selection	7826644
63411494	63411517	18	+	27260156	PANC0327	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.04466748848915911	[550]	[823,400,344,365]	0	hSpCas9	negative selection	7826645
63400658	63400681	18	-	27260156	NCIH2009	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.5235366347842076	[725]	[1764,1426,1240]	7	hSpCas9	negative selection	7883646
63400656	63400679	18	+	27260156	NCIH2009	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	-0.30326247439309784	[224]	[350,192,239]	-4	hSpCas9	negative selection	7883647
63410308	63410331	18	+	27260156	NCIH2009	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.15295838584229204	[1214]	[2112,1645,1948]	2	hSpCas9	negative selection	7883648
63411563	63411586	18	-	27260156	NCIH2009	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-1.717050446635764	[81]	[66,25,17]	-9	hSpCas9	negative selection	7947894
63410284	63410307	18	+	27260156	NCIH2009	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.2965389171323787	[1100]	[1717,1212,916]	-4	hSpCas9	negative selection	7947895
63411494	63411517	18	+	27260156	NCIH2009	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-1.1836725774560142	[550]	[402,272,353]	-8	hSpCas9	negative selection	7947896
63400658	63400681	18	-	27260156	NCIH1373	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.7465731313061421	[725]	[1133,1285,1161,493]	7	hSpCas9	negative selection	8004897
63400656	63400679	18	+	27260156	NCIH1373	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	-0.4245139414626702	[224]	[326,143,155,38]	-4	hSpCas9	negative selection	8004898
63410308	63410331	18	+	27260156	NCIH1373	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.7267876352834173	[1214]	[2745,1763,2745,483]	7	hSpCas9	negative selection	8004899
63411563	63411586	18	-	27260156	NCIH1373	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-1.4588611162351643	[81]	[22,10,61,9]	-9	hSpCas9	negative selection	8069145
63410284	63410307	18	+	27260156	NCIH1373	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.2618735231556065	[1100]	[1103,956,1258,207]	-3	hSpCas9	negative selection	8069146
63411494	63411517	18	+	27260156	NCIH1373	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-1.1502750840059883	[550]	[143,380,237,83]	-8	hSpCas9	negative selection	8069147
63400658	63400681	18	-	27260156	PATU8902	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.5746526723178735	[725]	[1807,1912,872,1588]	6	hSpCas9	negative selection	8126148
63400656	63400679	18	+	27260156	PATU8902	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	-0.34492461743336333	[224]	[103,205,305,369]	-3	hSpCas9	negative selection	8126149
63410308	63410331	18	+	27260156	PATU8902	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.4450518329655866	[1214]	[2790,2115,2123,2190]	4	hSpCas9	negative selection	8126150
63411563	63411586	18	-	27260156	PATU8902	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-2.0245608555506593	[81]	[5,32,31,41]	-9	hSpCas9	negative selection	8190396
63410284	63410307	18	+	27260156	PATU8902	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.009058105686692075	[1100]	[1574,1569,1092,2014]	0	hSpCas9	negative selection	8190397
63411494	63411517	18	+	27260156	PATU8902	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.6654889841922509	[550]	[475,495,435,542]	-6	hSpCas9	negative selection	8190398
63400658	63400681	18	-	27260156	PANC1	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.13132222018591855	[725]	[674,846,698,554]	2	hSpCas9	negative selection	8247399
63400656	63400679	18	+	27260156	PANC1	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.14577689658866566	[224]	[231,234,205,186]	2	hSpCas9	negative selection	8247400
63410308	63410331	18	+	27260156	PANC1	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.5871109356012405	[1214]	[1627,1807,1378,1488]	8	hSpCas9	negative selection	8247401
63411563	63411586	18	-	27260156	PANC1	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.555601164846109	[81]	[38,42,45,59]	-7	hSpCas9	negative selection	8311647
63410284	63410307	18	+	27260156	PANC1	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.24898718945019294	[1100]	[1094,1516,1201,798]	4	hSpCas9	negative selection	8311648
63411494	63411517	18	+	27260156	PANC1	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	0.21639347339302192	[550]	[582,646,736,287]	3	hSpCas9	negative selection	8311649
63400658	63400681	18	-	27260156	PANC0813	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.3197108114575429	[725]	[1353,1129,890,914]	5	hSpCas9	negative selection	8368650
63400656	63400679	18	+	27260156	PANC0813	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	-0.07561425017376422	[224]	[293,274,178,257]	-1	hSpCas9	negative selection	8368651
63410308	63410331	18	+	27260156	PANC0813	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.26358717072119764	[1214]	[1812,1787,1584,1674]	4	hSpCas9	negative selection	8368652
63411563	63411586	18	-	27260156	PANC0813	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.5502224419716364	[81]	[109,74,52,30]	-7	hSpCas9	negative selection	8432898
63410284	63410307	18	+	27260156	PANC0813	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.15504137659750006	[1100]	[1424,1106,1032,1105]	-3	hSpCas9	negative selection	8432899
63411494	63411517	18	+	27260156	PANC0813	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.4711336521106244	[550]	[565,474,409,426]	-6	hSpCas9	negative selection	8432900
63400658	63400681	18	-	27260156	RDES	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.34597909765382084	[725]	[858,996,1250,1180]	5	hSpCas9	negative selection	8489901
63400656	63400679	18	+	27260156	RDES	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.4385307111745542	[224]	[225,321,420,475]	7	hSpCas9	negative selection	8489902
63410308	63410331	18	+	27260156	RDES	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.6220541799848924	[1214]	[1653,2094,2316,2670]	8	hSpCas9	negative selection	8489903
63411563	63411586	18	-	27260156	RDES	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.1331764008339138	[81]	[71,40,140,98]	-2	hSpCas9	negative selection	8554149
63410284	63410307	18	+	27260156	RDES	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.12438586107520044	[1100]	[962,1072,1249,1418]	-2	hSpCas9	negative selection	8554150
63411494	63411517	18	+	27260156	RDES	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.19442903320155724	[550]	[565,471,511,666]	-3	hSpCas9	negative selection	8554151
63400658	63400681	18	-	27260156	PC3	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.021625468392229563	[725]	[414,467,1579,904]	0	hSpCas9	negative selection	8611152
63400656	63400679	18	+	27260156	PC3	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	-0.20932802315703625	[224]	[106,241,258,211]	-5	hSpCas9	negative selection	8611153
63410308	63410331	18	+	27260156	PC3	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.39919212682811844	[1214]	[989,1792,2516,1542]	8	hSpCas9	negative selection	8611154
63411563	63411586	18	-	27260156	PC3	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.016739041502054963	[81]	[58,23,228,80]	0	hSpCas9	negative selection	8675400
63410284	63410307	18	+	27260156	PC3	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.019569412877320502	[1100]	[599,1159,1762,1188]	0	hSpCas9	negative selection	8675401
63411494	63411517	18	+	27260156	PC3	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.25565923709116306	[550]	[320,469,680,464]	-5	hSpCas9	negative selection	8675402
63400658	63400681	18	-	27260156	PATU8988T	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.2783757935473742	[725]	[833,1051,709,825]	5	hSpCas9	negative selection	8732403
63400656	63400679	18	+	27260156	PATU8988T	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.13879862998865566	[224]	[270,285,242,154]	2	hSpCas9	negative selection	8732404
63410308	63410331	18	+	27260156	PATU8988T	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.45701090175561454	[1214]	[1529,1660,1503,1769]	7	hSpCas9	negative selection	8732405
63411563	63411586	18	-	27260156	PATU8988T	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.9117827641855181	[81]	[78,61,17,8]	-8	hSpCas9	negative selection	8796651
63410284	63410307	18	+	27260156	PATU8988T	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.026754760079749085	[1100]	[1222,1036,909,1169]	0	hSpCas9	negative selection	8796652
63411494	63411517	18	+	27260156	PATU8988T	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	0.022322823143827858	[550]	[489,535,649,479]	0	hSpCas9	negative selection	8796653
63400658	63400681	18	-	27260156	T47D	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.2444202515768258	[725]	[1071,905,1024,1012]	5	hSpCas9	negative selection	8853654
63400656	63400679	18	+	27260156	T47D	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	-0.08567040565437822	[224]	[345,201,239,202]	-2	hSpCas9	negative selection	8853655
63410308	63410331	18	+	27260156	T47D	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.5781612673865271	[1214]	[2033,2050,2213,2157]	9	hSpCas9	negative selection	8853656
63411563	63411586	18	-	27260156	T47D	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.11508540367190934	[81]	[83,80,83,104]	-3	hSpCas9	negative selection	8917902
63410284	63410307	18	+	27260156	T47D	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.07832068272505555	[1100]	[1283,1336,1180,1626]	1	hSpCas9	negative selection	8917903
63411494	63411517	18	+	27260156	T47D	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	0.11434497524929596	[550]	[647,697,676,757]	2	hSpCas9	negative selection	8917904
63400658	63400681	18	-	27260156	SU8686	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.34476054797525757	[725]	[835,718,1132,1018]	6	hSpCas9	negative selection	8974905
63400656	63400679	18	+	27260156	SU8686	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.1936963766135722	[224]	[214,166,250,429]	3	hSpCas9	negative selection	8974906
63410308	63410331	18	+	27260156	SU8686	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.264980539731406	[1214]	[1301,1316,1444,1806]	4	hSpCas9	negative selection	8974907
63411563	63411586	18	-	27260156	SU8686	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.5014277980620574	[81]	[46,47,81,54]	-7	hSpCas9	negative selection	9039153
63410284	63410307	18	+	27260156	SU8686	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.14835486355649152	[1100]	[912,939,1091,1007]	-3	hSpCas9	negative selection	9039154
63411494	63411517	18	+	27260156	SU8686	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.37225477203678725	[550]	[406,350,441,510]	-6	hSpCas9	negative selection	9039155
63400658	63400681	18	-	27260156	SKES1	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.3683335176602235	[725]	[1264,773,940,792]	7	hSpCas9	negative selection	9096156
63400656	63400679	18	+	27260156	SKES1	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.17295092772381038	[224]	[361,210,232,217]	4	hSpCas9	negative selection	9096157
63410308	63410331	18	+	27260156	SKES1	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.4932504820289334	[1214]	[1913,2002,1496,1485]	8	hSpCas9	negative selection	9096158
63411563	63411586	18	-	27260156	SKES1	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-1.0872441996427487	[81]	[53,44,31,26]	-9	hSpCas9	negative selection	9160404
63410284	63410307	18	+	27260156	SKES1	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	0.013751805729131483	[1100]	[1240,1388,955,914]	0	hSpCas9	negative selection	9160405
63411494	63411517	18	+	27260156	SKES1	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.20185182201131172	[550]	[533,587,376,434]	-4	hSpCas9	negative selection	9160406
63400658	63400681	18	-	27260156	TOV112D	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.08296383286153719	[725]	[733,1084,679,657]	1	hSpCas9	negative selection	9217407
63400656	63400679	18	+	27260156	TOV112D	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.059354716854155276	[224]	[363,152,191,220]	1	hSpCas9	negative selection	9217408
63410308	63410331	18	+	27260156	TOV112D	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.40322287140432045	[1214]	[1740,2401,1191,1313]	7	hSpCas9	negative selection	9217409
63411563	63411586	18	-	27260156	TOV112D	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	0.11331631853551238	[81]	[170,19,94,59]	2	hSpCas9	negative selection	9281655
63410284	63410307	18	+	27260156	TOV112D	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.04584911222574828	[1100]	[1004,1378,844,1111]	-1	hSpCas9	negative selection	9281656
63411494	63411517	18	+	27260156	TOV112D	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.15981483553175685	[550]	[343,631,545,474]	-3	hSpCas9	negative selection	9281657
63400658	63400681	18	-	27260156	TC71	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.1648746468297262	[725]	[910,908,880,781]	4	hSpCas9	negative selection	9338658
63400656	63400679	18	+	27260156	TC71	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.1012566050858178	[224]	[220,220,235,364]	2	hSpCas9	negative selection	9338659
63410308	63410331	18	+	27260156	TC71	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.563222494972736	[1214]	[1885,2019,1899,1890]	9	hSpCas9	negative selection	9338660
63411563	63411586	18	-	27260156	TC71	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-0.39464805263002933	[81]	[57,43,103,59]	-8	hSpCas9	negative selection	9402906
63410284	63410307	18	+	27260156	TC71	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.09050106400744928	[1100]	[911,1199,1239,1079]	-2	hSpCas9	negative selection	9402907
63411494	63411517	18	+	27260156	TC71	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.007085319378358074	[550]	[610,607,572,556]	0	hSpCas9	negative selection	9402908
63400658	63400681	18	-	27260156	TC32	viability	ATCCTATTATTTGGGCCGCCTGG	VPS4B	ENSG00000119541	0.3794402156670691	[725]	[797,601,1016,1243]	6	hSpCas9	negative selection	9459909
63400656	63400679	18	+	27260156	TC32	viability	TTCCAGGCGGCCCAAATAATAGG	VPS4B	ENSG00000119541	0.3251677779130214	[224]	[239,253,246,307]	6	hSpCas9	negative selection	9459910
63410308	63410331	18	+	27260156	TC32	viability	CTCGGCTGTCCTTCTTTCACTGG	VPS4B	ENSG00000119541	0.5560475434826735	[1214]	[1449,1081,2652,1870]	8	hSpCas9	negative selection	9459911
63411563	63411586	18	-	27260156	TC32	viability	CAAACAGAAAGCGATAGATCTGG	VPS4B	ENSG00000119541	-1.2955125419133844	[81]	[22,0,71,48]	-9	hSpCas9	negative selection	9524157
63410284	63410307	18	+	27260156	TC32	viability	ACGTACCCCTTCTCATCTGCTGG	VPS4B	ENSG00000119541	-0.0860431578005938	[1100]	[1030,739,1203,985]	-1	hSpCas9	negative selection	9524158
63411494	63411517	18	+	27260156	TC32	viability	CAGCATGCTGATAGAGCTGAAGG	VPS4B	ENSG00000119541	-0.25328569464503853	[550]	[357,401,501,484]	-4	hSpCas9	negative selection	9524159
63393464	63393487	18	+	27869803	HPAFII	viability after 27 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	-2.740885202743023	[214]	[35,0,NaN]	-9	hSpCas9	negative selection	9564926
63399251	63399274	18	+	27869803	HPAFII	viability after 27 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-2.3808752656202716	[280]	[41,16,NaN]	-8	hSpCas9	negative selection	9564927
63400069	63400092	18	-	27869803	HPAFII	viability after 27 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-1.0228375167737362	[311]	[83,77,NaN]	-6	hSpCas9	negative selection	9564928
63400652	63400675	18	-	27869803	HPAFII	viability after 27 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.1185138116812019	[229]	[109,148,NaN]	0	hSpCas9	negative selection	9564929
63410289	63410312	18	-	27869803	HPAFII	viability after 27 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-1.1185404097022178	[626]	[177,129,NaN]	-6	hSpCas9	negative selection	9564930
63411532	63411555	18	-	27869803	HPAFII	viability after 27 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-1.3670648861182542	[499]	[90,110,NaN]	-7	hSpCas9	negative selection	9564931
63393464	63393487	18	+	27869803	HPAFII	viability after 15 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	-1.5631095454871367	[214]	[55,91,NaN]	-8	hSpCas9	negative selection	9647375
63399251	63399274	18	+	27869803	HPAFII	viability after 15 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-1.114973791786289	[280]	[308,33,NaN]	-8	hSpCas9	negative selection	9647376
63400069	63400092	18	-	27869803	HPAFII	viability after 15 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.33435281641332165	[311]	[289,250,NaN]	-4	hSpCas9	negative selection	9647377
63400652	63400675	18	-	27869803	HPAFII	viability after 15 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.10577018776704669	[229]	[347,214,NaN]	1	hSpCas9	negative selection	9647378
63410289	63410312	18	-	27869803	HPAFII	viability after 15 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-1.4428192419995085	[626]	[348,184,NaN]	-8	hSpCas9	negative selection	9647379
63411532	63411555	18	-	27869803	HPAFII	viability after 15 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-1.0521041656491092	[499]	[453,137,NaN]	-8	hSpCas9	negative selection	9647380
63393464	63393487	18	+	27869803	ASPC1	viability after 36 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	0.6940931025180657	[426]	[122,334,246]	6	hSpCas9	negative selection	9729824
63399251	63399274	18	+	27869803	ASPC1	viability after 36 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-0.35797386446744145	[542]	[77,262,103]	-4	hSpCas9	negative selection	9729825
63400069	63400092	18	-	27869803	ASPC1	viability after 36 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	0.5015509876260745	[901]	[390,492,441]	5	hSpCas9	negative selection	9729826
63400652	63400675	18	-	27869803	ASPC1	viability after 36 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	0.5420826325720552	[560]	[262,285,296]	5	hSpCas9	negative selection	9729827
63410289	63410312	18	-	27869803	ASPC1	viability after 36 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-0.38945229656977154	[1251]	[456,249,309]	-4	hSpCas9	negative selection	9729828
63411532	63411555	18	-	27869803	ASPC1	viability after 36 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.06534859330637349	[809]	[270,395,166]	0	hSpCas9	negative selection	9729829
63393464	63393487	18	+	27869803	PATU8988S	viability after 35 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	-1.4832607675721405	[336]	[68,27,NaN]	-8	hSpCas9	negative selection	9812273
63399251	63399274	18	+	27869803	PATU8988S	viability after 35 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-6.649211003655401	[498]	[2,0,NaN]	-9	hSpCas9	negative selection	9812274
63400069	63400092	18	-	27869803	PATU8988S	viability after 35 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-1.2682318534106298	[624]	[106,101,NaN]	-8	hSpCas9	negative selection	9812275
63400652	63400675	18	-	27869803	PATU8988S	viability after 35 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	-0.10873436598625197	[383]	[111,174,NaN]	-1	hSpCas9	negative selection	9812276
63410289	63410312	18	-	27869803	PATU8988S	viability after 35 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-0.2537749900719762	[884]	[272,324,NaN]	-3	hSpCas9	negative selection	9812277
63411532	63411555	18	-	27869803	PATU8988S	viability after 35 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-1.6335845880157789	[919]	[82,155,NaN]	-8	hSpCas9	negative selection	9812278
63393464	63393487	18	+	27869803	PATU8988S	viability after 31 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	-0.9450668240738026	[336]	[49,94,NaN]	-7	hSpCas9	negative selection	9894722
63399251	63399274	18	+	27869803	PATU8988S	viability after 31 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-4.182360380017052	[498]	[6,15,NaN]	-9	hSpCas9	negative selection	9894723
63400069	63400092	18	-	27869803	PATU8988S	viability after 31 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-0.8661053563200396	[624]	[163,101,NaN]	-7	hSpCas9	negative selection	9894724
63400652	63400675	18	-	27869803	PATU8988S	viability after 31 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	-0.3072039853954265	[383]	[77,181,NaN]	-3	hSpCas9	negative selection	9894725
63410289	63410312	18	-	27869803	PATU8988S	viability after 31 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-0.7409598340497343	[884]	[149,288,NaN]	-7	hSpCas9	negative selection	9894726
63411532	63411555	18	-	27869803	PATU8988S	viability after 31 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-1.4068759481588513	[919]	[74,218,NaN]	-8	hSpCas9	negative selection	9894727
63393464	63393487	18	+	27869803	HPAFII	viability after 35 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	-4.5311401734229815	[214]	[7,0,NaN]	-9	hSpCas9	negative selection	9977171
63399251	63399274	18	+	27869803	HPAFII	viability after 35 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-2.3474287825271296	[280]	[50,1,NaN]	-8	hSpCas9	negative selection	9977172
63400069	63400092	18	-	27869803	HPAFII	viability after 35 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-1.575393211302374	[311]	[52,52,NaN]	-7	hSpCas9	negative selection	9977173
63400652	63400675	18	-	27869803	HPAFII	viability after 35 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	-0.4333622193781482	[229]	[65,108,NaN]	-3	hSpCas9	negative selection	9977174
63410289	63410312	18	-	27869803	HPAFII	viability after 35 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-1.3023249604361204	[626]	[123,133,NaN]	-6	hSpCas9	negative selection	9977175
63411532	63411555	18	-	27869803	HPAFII	viability after 35 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-1.6334640597267698	[499]	[74,88,NaN]	-7	hSpCas9	negative selection	9977176
63393464	63393487	18	+	27869803	HPAFII	viability after 31 days	TCAATGGCACCAGGGTCACCTGG	VPS4B	ENSG00000119541	-6.30939504663333	[214]	[1,0,NaN]	-9	hSpCas9	negative selection	10059620
63399251	63399274	18	+	27869803	HPAFII	viability after 31 days	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-3.2939877960364794	[280]	[28,1,NaN]	-9	hSpCas9	negative selection	10059621
63400069	63400092	18	-	27869803	HPAFII	viability after 31 days	AGCCGCACGTAGAATTAAGACGG	VPS4B	ENSG00000119541	-1.3156989896474998	[311]	[77,61,NaN]	-7	hSpCas9	negative selection	10059622
63400652	63400675	18	-	27869803	HPAFII	viability after 31 days	TTATTTGGGCCGCCTGGAACAGG	VPS4B	ENSG00000119541	-0.18957078132583488	[229]	[94,132,NaN]	-1	hSpCas9	negative selection	10059623
63410289	63410312	18	-	27869803	HPAFII	viability after 31 days	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-2.043027622646142	[626]	[93,75,NaN]	-8	hSpCas9	negative selection	10059624
63411532	63411555	18	-	27869803	HPAFII	viability after 31 days	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-1.7648423245437548	[499]	[72,92,NaN]	-7	hSpCas9	negative selection	10059625
63411532	63411555	18	-	28162770	P31FUJ	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.07597519184098124	[208]	[232]	0	hSpCas9	negative selection	10263871
63397133	63397156	18	-	28162770	P31FUJ	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	0.25062226984471536	[205]	[287]	2	hSpCas9	negative selection	10263872
63410289	63410312	18	-	28162770	P31FUJ	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.38145460310081586	[129]	[198]	4	hSpCas9	negative selection	10263873
63400684	63400707	18	-	28162770	P31FUJ	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	0.24499680135774682	[297]	[414]	2	hSpCas9	negative selection	10263874
63400643	63400666	18	+	28162770	P31FUJ	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	-0.5051198510825088	[1028]	[851]	-4	hSpCas9	negative selection	10263875
63399302	63399325	18	-	28162770	P31FUJ	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	-0.5478982658193158	[473]	[380]	-4	hSpCas9	negative selection	10263876
63399267	63399290	18	-	28162770	P31FUJ	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	0.18082572460979374	[255]	[340]	2	hSpCas9	negative selection	10263877
63399251	63399274	18	+	28162770	P31FUJ	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-0.2054257654830734	[260]	[265]	-2	hSpCas9	negative selection	10263878
63393514	63393537	18	+	28162770	P31FUJ	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	0.38386915603411553	[404]	[620]	4	hSpCas9	negative selection	10263879
63410317	63410340	18	-	28162770	P31FUJ	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.372225919360883	[356]	[542]	4	hSpCas9	negative selection	10263880
63411532	63411555	18	-	28162770	TF1	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	NaN	[NaN]	[273]	1	hSpCas9	negative selection	10433237
63397133	63397156	18	-	28162770	TF1	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	NaN	[NaN]	[180]	1	hSpCas9	negative selection	10433238
63410289	63410312	18	-	28162770	TF1	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10433239
63400684	63400707	18	-	28162770	TF1	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	NaN	[NaN]	[193]	1	hSpCas9	negative selection	10433240
63400643	63400666	18	+	28162770	TF1	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	NaN	[NaN]	[940]	1	hSpCas9	negative selection	10433241
63399302	63399325	18	-	28162770	TF1	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	NaN	[NaN]	[421]	1	hSpCas9	negative selection	10433242
63399267	63399290	18	-	28162770	TF1	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	NaN	[NaN]	[357]	1	hSpCas9	negative selection	10433243
63399251	63399274	18	+	28162770	TF1	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	NaN	[NaN]	[250]	1	hSpCas9	negative selection	10433244
63393514	63393537	18	+	28162770	TF1	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	NaN	[NaN]	[251]	1	hSpCas9	negative selection	10433245
63410317	63410340	18	-	28162770	TF1	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	NaN	[NaN]	[280]	1	hSpCas9	negative selection	10433246
63411532	63411555	18	-	28162770	SKM1	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.548240885595153	[66]	[80]	-4	hSpCas9	negative selection	10602603
63397133	63397156	18	-	28162770	SKM1	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	0.4999263968653568	[45]	[114]	5	hSpCas9	negative selection	10602604
63410289	63410312	18	-	28162770	SKM1	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.06434152018242723	[32]	[60]	0	hSpCas9	negative selection	10602605
63400684	63400707	18	-	28162770	SKM1	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	-0.3985026199949654	[84]	[113]	-3	hSpCas9	negative selection	10602606
63400643	63400666	18	+	28162770	SKM1	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	-0.059441922438957295	[256]	[435]	0	hSpCas9	negative selection	10602607
63399302	63399325	18	-	28162770	SKM1	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	-0.13867406745787259	[136]	[219]	-1	hSpCas9	negative selection	10602608
63399267	63399290	18	-	28162770	SKM1	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	-0.14916644127551495	[68]	[109]	-1	hSpCas9	negative selection	10602609
63399251	63399274	18	+	28162770	SKM1	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.3479233034203068	[55]	[125]	3	hSpCas9	negative selection	10602610
63393514	63393537	18	+	28162770	SKM1	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	-0.026821489910503704	[67]	[117]	0	hSpCas9	negative selection	10602611
63410317	63410340	18	-	28162770	SKM1	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.7048578481355823	[75]	[218]	6	hSpCas9	negative selection	10602612
63411532	63411555	18	-	28162770	SKM1	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.548240885595153	[66]	[80]	-4	hSpCas9	negative selection	10771969
63397133	63397156	18	-	28162770	SKM1	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	0.4999263968653568	[45]	[114]	5	hSpCas9	negative selection	10771970
63410289	63410312	18	-	28162770	SKM1	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.06434152018242723	[32]	[60]	0	hSpCas9	negative selection	10771971
63400684	63400707	18	-	28162770	SKM1	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	-0.3985026199949654	[84]	[113]	-3	hSpCas9	negative selection	10771972
63400643	63400666	18	+	28162770	SKM1	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	-0.059441922438957295	[256]	[435]	0	hSpCas9	negative selection	10771973
63399302	63399325	18	-	28162770	SKM1	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	-0.13867406745787259	[136]	[219]	-1	hSpCas9	negative selection	10771974
63399267	63399290	18	-	28162770	SKM1	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	-0.14916644127551495	[68]	[109]	-1	hSpCas9	negative selection	10771975
63399251	63399274	18	+	28162770	SKM1	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.3479233034203068	[55]	[125]	3	hSpCas9	negative selection	10771976
63393514	63393537	18	+	28162770	SKM1	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	-0.026821489910503704	[67]	[117]	0	hSpCas9	negative selection	10771977
63410317	63410340	18	-	28162770	SKM1	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.7048578481355823	[75]	[218]	6	hSpCas9	negative selection	10771978
63411532	63411555	18	-	28162770	PL21	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.5446033302686052	[247]	[73]	-4	hSpCas9	negative selection	10941335
63397133	63397156	18	-	28162770	PL21	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	0.6921995339920091	[154]	[108]	6	hSpCas9	negative selection	10941336
63410289	63410312	18	-	28162770	PL21	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-0.0728788799170958	[144]	[59]	0	hSpCas9	negative selection	10941337
63400684	63400707	18	-	28162770	PL21	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	0.27510167217054216	[299]	[157]	2	hSpCas9	negative selection	10941338
63400643	63400666	18	+	28162770	PL21	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	-0.31865596226609005	[830]	[289]	-2	hSpCas9	negative selection	10941339
63399302	63399325	18	-	28162770	PL21	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	0.6044620880825435	[472]	[312]	5	hSpCas9	negative selection	10941340
63399267	63399290	18	-	28162770	PL21	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	0.824994842333989	[213]	[164]	7	hSpCas9	negative selection	10941341
63399251	63399274	18	+	28162770	PL21	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.3889012579444879	[185]	[105]	3	hSpCas9	negative selection	10941342
63393514	63393537	18	+	28162770	PL21	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	0.25303456292144566	[240]	[124]	2	hSpCas9	negative selection	10941343
63410317	63410340	18	-	28162770	PL21	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	-1.4070186323460323	[261]	[42]	-7	hSpCas9	negative selection	10941344
63411532	63411555	18	-	28162770	P31FUJ	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.07597519184098124	[208]	[232]	0	hSpCas9	negative selection	11110701
63397133	63397156	18	-	28162770	P31FUJ	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	0.25062226984471536	[205]	[287]	2	hSpCas9	negative selection	11110702
63410289	63410312	18	-	28162770	P31FUJ	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.38145460310081586	[129]	[198]	4	hSpCas9	negative selection	11110703
63400684	63400707	18	-	28162770	P31FUJ	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	0.24499680135774682	[297]	[414]	2	hSpCas9	negative selection	11110704
63400643	63400666	18	+	28162770	P31FUJ	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	-0.5051198510825088	[1028]	[851]	-4	hSpCas9	negative selection	11110705
63399302	63399325	18	-	28162770	P31FUJ	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	-0.5478982658193158	[473]	[380]	-4	hSpCas9	negative selection	11110706
63399267	63399290	18	-	28162770	P31FUJ	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	0.18082572460979374	[255]	[340]	2	hSpCas9	negative selection	11110707
63399251	63399274	18	+	28162770	P31FUJ	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-0.2054257654830734	[260]	[265]	-2	hSpCas9	negative selection	11110708
63393514	63393537	18	+	28162770	P31FUJ	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	0.38386915603411553	[404]	[620]	4	hSpCas9	negative selection	11110709
63410317	63410340	18	-	28162770	P31FUJ	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.372225919360883	[356]	[542]	4	hSpCas9	negative selection	11110710
63411532	63411555	18	-	28162770	OCIAML5	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.15963937277428933	[124]	[201]	-1	hSpCas9	negative selection	11280067
63397133	63397156	18	-	28162770	OCIAML5	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	0.5210402479489282	[143]	[372]	4	hSpCas9	negative selection	11280068
63410289	63410312	18	-	28162770	OCIAML5	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	-0.38339110798307996	[98]	[136]	-3	hSpCas9	negative selection	11280069
63400684	63400707	18	-	28162770	OCIAML5	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	0.5039090048510427	[133]	[342]	4	hSpCas9	negative selection	11280070
63400643	63400666	18	+	28162770	OCIAML5	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	0.12667786909595202	[546]	[1077]	1	hSpCas9	negative selection	11280071
63399302	63399325	18	-	28162770	OCIAML5	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	0.2912976043071802	[334]	[739]	2	hSpCas9	negative selection	11280072
63399267	63399290	18	-	28162770	OCIAML5	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	0.3900082163341506	[155]	[368]	3	hSpCas9	negative selection	11280073
63399251	63399274	18	+	28162770	OCIAML5	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-0.12443884127712712	[185]	[307]	-1	hSpCas9	negative selection	11280074
63393514	63393537	18	+	28162770	OCIAML5	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	-0.06110060934542605	[214]	[371]	0	hSpCas9	negative selection	11280075
63410317	63410340	18	-	28162770	OCIAML5	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.2524275970071087	[212]	[457]	2	hSpCas9	negative selection	11280076
63411532	63411555	18	-	28162770	EOL1	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.48462272067631296	[408]	[153]	-4	hSpCas9	negative selection	11449433
63397133	63397156	18	-	28162770	EOL1	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	0.20344858286334944	[210]	[127]	1	hSpCas9	negative selection	11449434
63410289	63410312	18	-	28162770	EOL1	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.6093455398714855	[213]	[171]	5	hSpCas9	negative selection	11449435
63400684	63400707	18	-	28162770	EOL1	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	0.5272811328200409	[510]	[387]	5	hSpCas9	negative selection	11449436
63400643	63400666	18	+	28162770	EOL1	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	0.6741118527719632	[1618]	[1360]	6	hSpCas9	negative selection	11449437
63399302	63399325	18	-	28162770	EOL1	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	0.10288501282904705	[759]	[429]	0	hSpCas9	negative selection	11449438
63399267	63399290	18	-	28162770	EOL1	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	0.5770254952663303	[326]	[256]	5	hSpCas9	negative selection	11449439
63399251	63399274	18	+	28162770	EOL1	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.9888981829805921	[284]	[297]	8	hSpCas9	negative selection	11449440
63393514	63393537	18	+	28162770	EOL1	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	1.0466493793017224	[350]	[381]	8	hSpCas9	negative selection	11449441
63410317	63410340	18	-	28162770	EOL1	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.37680773480557694	[439]	[300]	3	hSpCas9	negative selection	11449442
63411532	63411555	18	-	28162770	MOLM13	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	1.051263885362543	[302]	[453]	7	hSpCas9	negative selection	11618799
63397133	63397156	18	-	28162770	MOLM13	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	-0.975717269931036	[271]	[99]	-5	hSpCas9	negative selection	11618800
63410289	63410312	18	-	28162770	MOLM13	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.4597615006611785	[177]	[176]	3	hSpCas9	negative selection	11618801
63400684	63400707	18	-	28162770	MOLM13	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	0.08975146507726417	[385]	[296]	0	hSpCas9	negative selection	11618802
63400643	63400666	18	+	28162770	MOLM13	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	-0.07614285512169516	[1250]	[857]	0	hSpCas9	negative selection	11618803
63399302	63399325	18	-	28162770	MOLM13	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	0.4993676130177469	[679]	[694]	4	hSpCas9	negative selection	11618804
63399267	63399290	18	-	28162770	MOLM13	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	-0.6863112676047172	[364]	[163]	-4	hSpCas9	negative selection	11618805
63399251	63399274	18	+	28162770	MOLM13	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.21340008484379364	[302]	[253]	1	hSpCas9	negative selection	11618806
63393514	63393537	18	+	28162770	MOLM13	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	0.24667515140541219	[407]	[349]	1	hSpCas9	negative selection	11618807
63410317	63410340	18	-	28162770	MOLM13	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.07343275968818708	[463]	[352]	0	hSpCas9	negative selection	11618808
63411532	63411555	18	-	28162770	HEL	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	0.8844697246259281	[306]	[362]	7	hSpCas9	negative selection	11788165
63397133	63397156	18	-	28162770	HEL	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	0.8719849243778675	[179]	[210]	7	hSpCas9	negative selection	11788166
63410289	63410312	18	-	28162770	HEL	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.24925747608796056	[154]	[117]	2	hSpCas9	negative selection	11788167
63400684	63400707	18	-	28162770	HEL	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	0.41313292043133454	[400]	[341]	3	hSpCas9	negative selection	11788168
63400643	63400666	18	+	28162770	HEL	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	0.4409665097680837	[1041]	[905]	3	hSpCas9	negative selection	11788169
63399302	63399325	18	-	28162770	HEL	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	0.5066772824243284	[599]	[545]	4	hSpCas9	negative selection	11788170
63399267	63399290	18	-	28162770	HEL	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	0.7128430704647055	[240]	[252]	6	hSpCas9	negative selection	11788171
63399251	63399274	18	+	28162770	HEL	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.8322166308640699	[227]	[259]	7	hSpCas9	negative selection	11788172
63393514	63393537	18	+	28162770	HEL	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	-0.12188310506871475	[315]	[185]	-1	hSpCas9	negative selection	11788173
63410317	63410340	18	-	28162770	HEL	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.05016314716932546	[379]	[251]	0	hSpCas9	negative selection	11788174
63411532	63411555	18	-	28162770	MV411	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	0.2961113975184648	[203]	[210]	2	hSpCas9	negative selection	11957531
63397133	63397156	18	-	28162770	MV411	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	1.0243118663856179	[163]	[280]	8	hSpCas9	negative selection	11957532
63410289	63410312	18	-	28162770	MV411	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.42943538452566266	[118]	[134]	4	hSpCas9	negative selection	11957533
63400684	63400707	18	-	28162770	MV411	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	0.42904435727272294	[327]	[371]	4	hSpCas9	negative selection	11957534
63400643	63400666	18	+	28162770	MV411	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	-0.24954911396625157	[826]	[585]	-2	hSpCas9	negative selection	11957535
63399302	63399325	18	-	28162770	MV411	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	-0.3595512562683796	[395]	[259]	-3	hSpCas9	negative selection	11957536
63399267	63399290	18	-	28162770	MV411	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	0.45388842825020154	[233]	[269]	4	hSpCas9	negative selection	11957537
63399251	63399274	18	+	28162770	MV411	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	0.3165995752901708	[223]	[234]	3	hSpCas9	negative selection	11957538
63393514	63393537	18	+	28162770	MV411	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	0.2623364271621137	[288]	[291]	2	hSpCas9	negative selection	11957539
63410317	63410340	18	-	28162770	MV411	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.4354061415156981	[308]	[351]	4	hSpCas9	negative selection	11957540
63411532	63411555	18	-	28162770	MONOMAC1	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.4354415863846325	[150]	[127]	-4	hSpCas9	negative selection	12126897
63397133	63397156	18	-	28162770	MONOMAC1	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	0.7163754679443557	[102]	[193]	6	hSpCas9	negative selection	12126898
63410289	63410312	18	-	28162770	MONOMAC1	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.29963912124364755	[72]	[102]	3	hSpCas9	negative selection	12126899
63400684	63400707	18	-	28162770	MONOMAC1	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	1.101853711750938	[201]	[496]	8	hSpCas9	negative selection	12126900
63400643	63400666	18	+	28162770	MONOMAC1	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	0.5943765311290288	[493]	[854]	6	hSpCas9	negative selection	12126901
63399302	63399325	18	-	28162770	MONOMAC1	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	0.3956613024412079	[247]	[373]	4	hSpCas9	negative selection	12126902
63399267	63399290	18	-	28162770	MONOMAC1	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	1.390718868553283	[171]	[516]	9	hSpCas9	negative selection	12126903
63399251	63399274	18	+	28162770	MONOMAC1	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	1.106743901117549	[127]	[315]	8	hSpCas9	negative selection	12126904
63393514	63393537	18	+	28162770	MONOMAC1	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	0.7814299913908049	[134]	[265]	7	hSpCas9	negative selection	12126905
63410317	63410340	18	-	28162770	MONOMAC1	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	-0.28307667812624515	[189]	[178]	-3	hSpCas9	negative selection	12126906
63411532	63411555	18	-	28162770	OCIAML2	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.10026137529704596	[40]	[211]	-1	hSpCas9	negative selection	12296263
63397133	63397156	18	-	28162770	OCIAML2	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	-0.3130885482556814	[25]	[115]	-3	hSpCas9	negative selection	12296264
63410289	63410312	18	-	28162770	OCIAML2	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.7231419181545189	[19]	[182]	7	hSpCas9	negative selection	12296265
63400684	63400707	18	-	28162770	OCIAML2	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	-0.11379611540659729	[48]	[250]	-1	hSpCas9	negative selection	12296266
63400643	63400666	18	+	28162770	OCIAML2	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	-0.9756094498338037	[181]	[512]	-6	hSpCas9	negative selection	12296267
63399302	63399325	18	-	28162770	OCIAML2	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	0.05132287795319446	[77]	[447]	0	hSpCas9	negative selection	12296268
63399267	63399290	18	-	28162770	OCIAML2	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	-0.742709370678962	[47]	[158]	-5	hSpCas9	negative selection	12296269
63399251	63399274	18	+	28162770	OCIAML2	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-0.32623991590698626	[37]	[167]	-3	hSpCas9	negative selection	12296270
63393514	63393537	18	+	28162770	OCIAML2	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	-1.264178947774735	[51]	[119]	-7	hSpCas9	negative selection	12296271
63410317	63410340	18	-	28162770	OCIAML2	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	0.11433267547899478	[44]	[269]	1	hSpCas9	negative selection	12296272
63411532	63411555	18	-	28162770	OCIAML3	viability	GCAGCGCAAGAAGACAAGGCTGG	VPS4B	ENSG00000119541	-0.2534638672694537	[76]	[194]	-2	hSpCas9	negative selection	12465629
63397133	63397156	18	-	28162770	OCIAML3	viability	CAGACTTTCGGGAACTTGGGAGG	VPS4B	ENSG00000119541	0.27434835386536577	[42]	[156]	2	hSpCas9	negative selection	12465630
63410289	63410312	18	-	28162770	OCIAML3	viability	CGAGTCCAGCAGATGAGAAGGGG	VPS4B	ENSG00000119541	0.11540223132148164	[36]	[120]	1	hSpCas9	negative selection	12465631
63400684	63400707	18	-	28162770	OCIAML3	viability	TAGGCAAGAGAACACCTTGGAGG	VPS4B	ENSG00000119541	1.29838338558924	[79]	[593]	9	hSpCas9	negative selection	12465632
63400643	63400666	18	+	28162770	OCIAML3	viability	TAGGACTTTCCTGTTCCAGGCGG	VPS4B	ENSG00000119541	0.8008519770170506	[242]	[1277]	7	hSpCas9	negative selection	12465633
63399302	63399325	18	-	28162770	OCIAML3	viability	GGGGTTGGTGTAGACAATGATGG	VPS4B	ENSG00000119541	1.204019479578322	[132]	[924]	8	hSpCas9	negative selection	12465634
63399267	63399290	18	-	28162770	OCIAML3	viability	GGGAGCTACAAATATACCCTGGG	VPS4B	ENSG00000119541	-0.2494781164996681	[75]	[192]	-2	hSpCas9	negative selection	12465635
63399251	63399274	18	+	28162770	OCIAML3	viability	ATGGCAGAATCCAGAACCCAGGG	VPS4B	ENSG00000119541	-0.12311690631180183	[56]	[157]	-1	hSpCas9	negative selection	12465636
63393514	63393537	18	+	28162770	OCIAML3	viability	AAGATGGTTAGGATCAGCTCGGG	VPS4B	ENSG00000119541	0.5455437120746305	[63]	[281]	5	hSpCas9	negative selection	12465637
63410317	63410340	18	-	28162770	OCIAML3	viability	GCACAGAAGCCAGTGAAAGAAGG	VPS4B	ENSG00000119541	-0.3015567465136346	[88]	[217]	-2	hSpCas9	negative selection	12465638