| 159854950 | 159854973 | 1 | + | 26472758 | Jiyoye | viability | GCGTCGGGTACCCCAGGAGGTGG | VSIG8 | ENSG00000243284 | 0.38831635425455746 | [230] | [227] | 3 | hSpCas9 | negative selection | 18982 | 159854960 | 159854983 | 1 | - | 26472758 | Jiyoye | viability | GCCGCGTCACCCACCTCCTGGGG | VSIG8 | ENSG00000243284 | 1.284492861731045 | [91] | [168] | 7 | hSpCas9 | negative selection | 18983 | 159854934 | 159854957 | 1 | + | 26472758 | Jiyoye | viability | GAGCGGCTGACGTTCTGCGTCGG | VSIG8 | ENSG00000243284 | 0.029701295183512916 | [138] | [106] | 0 | hSpCas9 | negative selection | 18984 | 159854819 | 159854842 | 1 | + | 26472758 | Jiyoye | viability | GACCTTGACGTAGACCGGGGAGG | VSIG8 | ENSG00000243284 | 0.2982410099527094 | [109] | [101] | 2 | hSpCas9 | negative selection | 18985 | 159855189 | 159855212 | 1 | - | 26472758 | Jiyoye | viability | GCAGGGTCGCCGACCCAGGAAGG | VSIG8 | ENSG00000243284 | 1.316027493447678 | [48] | [91] | 7 | hSpCas9 | negative selection | 18986 | 159855013 | 159855036 | 1 | - | 26472758 | Jiyoye | viability | TTTCCACAGAGAGGACGCCGTGG | VSIG8 | ENSG00000243284 | 0.5473530395541338 | [97] | [107] | 4 | hSpCas9 | negative selection | 18987 | 159854911 | 159854934 | 1 | + | 26472758 | Jiyoye | viability | GAGGCGCGTACTTGCGGCGCAGG | VSIG8 | ENSG00000243284 | -0.032109664019647655 | [79] | [58] | 0 | hSpCas9 | negative selection | 18988 | 159854787 | 159854810 | 1 | - | 26472758 | Jiyoye | viability | GAGCCGGCTGACTGCGCCGAGGG | VSIG8 | ENSG00000243284 | 0.2759308482276207 | [114] | [104] | 2 | hSpCas9 | negative selection | 18989 | 159856539 | 159856562 | 1 | - | 26472758 | Jiyoye | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | -0.6489676965316602 | [261] | [125] | -4 | hSpCas9 | negative selection | 180384 | 159855928 | 159855951 | 1 | - | 26472758 | Jiyoye | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | 0.9435191770068508 | [170] | [247] | 6 | hSpCas9 | negative selection | 180385 | 159856592 | 159856615 | 1 | - | 26472758 | Jiyoye | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | 0.14844111310570507 | [267] | [223] | 1 | hSpCas9 | negative selection | 180386 | 159856572 | 159856595 | 1 | - | 26472758 | Jiyoye | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | -0.31271669930139123 | [139] | [84] | -2 | hSpCas9 | negative selection | 180387 | 159854950 | 159854973 | 1 | + | 26472758 | KBM7 | viability | GCGTCGGGTACCCCAGGAGGTGG | VSIG8 | ENSG00000243284 | 0.2655133432657483 | [675,463] | [428,217] | 2 | hSpCas9 | negative selection | 210100 | 159854960 | 159854983 | 1 | - | 26472758 | KBM7 | viability | GCCGCGTCACCCACCTCCTGGGG | VSIG8 | ENSG00000243284 | 0.8447743464903386 | [456,448] | [401,367] | 8 | hSpCas9 | negative selection | 210101 | 159854934 | 159854957 | 1 | + | 26472758 | KBM7 | viability | GAGCGGCTGACGTTCTGCGTCGG | VSIG8 | ENSG00000243284 | 0.3070457819782485 | [721,583] | [507,260] | 3 | hSpCas9 | negative selection | 210102 | 159854819 | 159854842 | 1 | + | 26472758 | KBM7 | viability | GACCTTGACGTAGACCGGGGAGG | VSIG8 | ENSG00000243284 | 0.6254773497701964 | [668,536] | [469,402] | 6 | hSpCas9 | negative selection | 210103 | 159855189 | 159855212 | 1 | - | 26472758 | KBM7 | viability | GCAGGGTCGCCGACCCAGGAAGG | VSIG8 | ENSG00000243284 | -0.7409798314811473 | [266,112] | [60,42] | -6 | hSpCas9 | negative selection | 210104 | 159855013 | 159855036 | 1 | - | 26472758 | KBM7 | viability | TTTCCACAGAGAGGACGCCGTGG | VSIG8 | ENSG00000243284 | -0.17549891823204777 | [576,320] | [174,188] | -2 | hSpCas9 | negative selection | 210105 | 159854911 | 159854934 | 1 | + | 26472758 | KBM7 | viability | GAGGCGCGTACTTGCGGCGCAGG | VSIG8 | ENSG00000243284 | 0.7508581606144744 | [367,346] | [360,213] | 7 | hSpCas9 | negative selection | 210106 | 159854787 | 159854810 | 1 | - | 26472758 | KBM7 | viability | GAGCCGGCTGACTGCGCCGAGGG | VSIG8 | ENSG00000243284 | 0.706566031725635 | [548,581] | [487,391] | 7 | hSpCas9 | negative selection | 210107 | 159856539 | 159856562 | 1 | - | 26472758 | KBM7 | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | 0.2700149659618123 | [992,797] | [503,504] | 3 | hSpCas9 | negative selection | 371502 | 159855928 | 159855951 | 1 | - | 26472758 | KBM7 | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | 0.8963860740564568 | [1018,681] | [630,823] | 8 | hSpCas9 | negative selection | 371503 | 159856592 | 159856615 | 1 | - | 26472758 | KBM7 | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | -0.3823709215281459 | [1009,954] | [352,356] | -4 | hSpCas9 | negative selection | 371504 | 159856572 | 159856595 | 1 | - | 26472758 | KBM7 | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 0.7136803106920573 | [355,365] | [192,357] | 7 | hSpCas9 | negative selection | 371505 | 159854950 | 159854973 | 1 | + | 26472758 | Raji | viability | GCGTCGGGTACCCCAGGAGGTGG | VSIG8 | ENSG00000243284 | 1.06521408112966 | [242] | [117] | 8 | hSpCas9 | negative selection | 401218 | 159854960 | 159854983 | 1 | - | 26472758 | Raji | viability | GCCGCGTCACCCACCTCCTGGGG | VSIG8 | ENSG00000243284 | -0.4001002126698393 | [289] | [50] | -3 | hSpCas9 | negative selection | 401219 | 159854934 | 159854957 | 1 | + | 26472758 | Raji | viability | GAGCGGCTGACGTTCTGCGTCGG | VSIG8 | ENSG00000243284 | 0.019920694123260044 | [254] | [59] | 0 | hSpCas9 | negative selection | 401220 | 159854819 | 159854842 | 1 | + | 26472758 | Raji | viability | GACCTTGACGTAGACCGGGGAGG | VSIG8 | ENSG00000243284 | -0.02754604471250907 | [223] | [50] | 0 | hSpCas9 | negative selection | 401221 | 159855189 | 159855212 | 1 | - | 26472758 | Raji | viability | GCAGGGTCGCCGACCCAGGAAGG | VSIG8 | ENSG00000243284 | -1.528205038417525 | [86] | [6] | -8 | hSpCas9 | negative selection | 401222 | 159855013 | 159855036 | 1 | - | 26472758 | Raji | viability | TTTCCACAGAGAGGACGCCGTGG | VSIG8 | ENSG00000243284 | -0.06949422671047997 | [207] | [45] | 0 | hSpCas9 | negative selection | 401223 | 159854911 | 159854934 | 1 | + | 26472758 | Raji | viability | GAGGCGCGTACTTGCGGCGCAGG | VSIG8 | ENSG00000243284 | 0.08946162737633723 | [161] | [39] | 0 | hSpCas9 | negative selection | 401224 | 159854787 | 159854810 | 1 | - | 26472758 | Raji | viability | GAGCCGGCTGACTGCGCCGAGGG | VSIG8 | ENSG00000243284 | -0.01537635799003273 | [330] | [75] | 0 | hSpCas9 | negative selection | 401225 | 159856539 | 159856562 | 1 | - | 26472758 | Raji | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | -0.3902868875513893 | [496] | [87] | -3 | hSpCas9 | negative selection | 562620 | 159855928 | 159855951 | 1 | - | 26472758 | Raji | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | -0.003510056138624318 | [418] | [96] | 0 | hSpCas9 | negative selection | 562621 | 159856592 | 159856615 | 1 | - | 26472758 | Raji | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | 1.0114144768428774 | [403] | [188] | 8 | hSpCas9 | negative selection | 562622 | 159856572 | 159856595 | 1 | - | 26472758 | Raji | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 0.10738353537359946 | [127] | [31] | 1 | hSpCas9 | negative selection | 562623 | 159854950 | 159854973 | 1 | + | 26472758 | K562 | viability | GCGTCGGGTACCCCAGGAGGTGG | VSIG8 | ENSG00000243284 | 0.6499334528267842 | [455] | [603] | 5 | hSpCas9 | negative selection | 592336 | 159854960 | 159854983 | 1 | - | 26472758 | K562 | viability | GCCGCGTCACCCACCTCCTGGGG | VSIG8 | ENSG00000243284 | 0.3551657931739856 | [375] | [405] | 2 | hSpCas9 | negative selection | 592337 | 159854934 | 159854957 | 1 | + | 26472758 | K562 | viability | GAGCGGCTGACGTTCTGCGTCGG | VSIG8 | ENSG00000243284 | 0.5793103554042044 | [420] | [530] | 5 | hSpCas9 | negative selection | 592338 | 159854819 | 159854842 | 1 | + | 26472758 | K562 | viability | GACCTTGACGTAGACCGGGGAGG | VSIG8 | ENSG00000243284 | 0.19379265459647882 | [492] | [475] | 1 | hSpCas9 | negative selection | 592339 | 159855189 | 159855212 | 1 | - | 26472758 | K562 | viability | GCAGGGTCGCCGACCCAGGAAGG | VSIG8 | ENSG00000243284 | -1.2816500840011409 | [215] | [74] | -6 | hSpCas9 | negative selection | 592340 | 159855013 | 159855036 | 1 | - | 26472758 | K562 | viability | TTTCCACAGAGAGGACGCCGTGG | VSIG8 | ENSG00000243284 | -0.38609592486911665 | [369] | [238] | -3 | hSpCas9 | negative selection | 592341 | 159854911 | 159854934 | 1 | + | 26472758 | K562 | viability | GAGGCGCGTACTTGCGGCGCAGG | VSIG8 | ENSG00000243284 | 0.6987971185774589 | [207] | [284] | 6 | hSpCas9 | negative selection | 592342 | 159854787 | 159854810 | 1 | - | 26472758 | K562 | viability | GAGCCGGCTGACTGCGCCGAGGG | VSIG8 | ENSG00000243284 | 0.43150428026694243 | [584] | [665] | 3 | hSpCas9 | negative selection | 592343 | 159856539 | 159856562 | 1 | - | 26472758 | K562 | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | 1.1786460278454187 | [818] | [1564] | 8 | hSpCas9 | negative selection | 753738 | 159855928 | 159855951 | 1 | - | 26472758 | K562 | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | 0.391334575753722 | [624] | [691] | 3 | hSpCas9 | negative selection | 753739 | 159856592 | 159856615 | 1 | - | 26472758 | K562 | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | 0.44342293207543126 | [763] | [876] | 3 | hSpCas9 | negative selection | 753740 | 159856572 | 159856595 | 1 | - | 26472758 | K562 | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 0.8522816304976818 | [249] | [380] | 7 | hSpCas9 | negative selection | 753741 | 159854803 | 159854826 | 1 | - | 26627737 | DLD1 | viability | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | 0.3065701685257187 | [110] | [57,55,18] | 3 | hSpCas9 | negative selection | 766877 | 159856056 | 159856079 | 1 | + | 26627737 | DLD1 | viability | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | -0.3728995607182337 | [192] | [14,54,66] | -4 | hSpCas9 | negative selection | 766878 | 159854803 | 159854826 | 1 | - | 26627737 | GBM cells | viability after 5 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | -0.22661700719817313 | [155] | [63,78] | -4 | hSpCas9 | negative selection | 849192 | 159856056 | 159856079 | 1 | + | 26627737 | GBM cells | viability after 5 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 0.36980460889804667 | [56] | [42,35] | 5 | hSpCas9 | negative selection | 849193 | 159854803 | 159854826 | 1 | - | 26627737 | GBM cells | viability after 13 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | -0.1288181627988989 | [155] | [72,80] | -1 | hSpCas9 | negative selection | 931507 | 159856056 | 159856079 | 1 | + | 26627737 | GBM cells | viability after 13 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 0.35862258667392655 | [56] | [37,40] | 4 | hSpCas9 | negative selection | 931508 | 159854803 | 159854826 | 1 | - | 26627737 | GBM cells | viability after 21 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | -0.3781230227989505 | [155] | [71,58] | -3 | hSpCas9 | negative selection | 1013822 | 159856056 | 159856079 | 1 | + | 26627737 | GBM cells | viability after 21 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | -0.07110085065006189 | [56] | [29,28] | 0 | hSpCas9 | negative selection | 1013823 | 159854803 | 159854826 | 1 | - | 26627737 | RPE1 | viability after 9 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | 0.6511852079695133 | [249] | [80,176] | 4 | hSpCas9 | negative selection | 1096137 | 159856056 | 159856079 | 1 | + | 26627737 | RPE1 | viability after 9 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | -3.0484045744363244 | [1091] | [15,73] | -9 | hSpCas9 | negative selection | 1096138 | 159854803 | 159854826 | 1 | - | 26627737 | RPE1 | viability after 12 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | 0.15969531095897116 | [249] | [58,91] | 1 | hSpCas9 | negative selection | 1178452 | 159856056 | 159856079 | 1 | + | 26627737 | RPE1 | viability after 12 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | -2.9860787433070564 | [1091] | [20,53] | -9 | hSpCas9 | negative selection | 1178453 | 159854803 | 159854826 | 1 | - | 26627737 | RPE1 | viability after 15 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | -0.016291965396552976 | [249] | [45,92] | 0 | hSpCas9 | negative selection | 1260767 | 159856056 | 159856079 | 1 | + | 26627737 | RPE1 | viability after 15 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | -4.194337744665749 | [1091] | [23,9] | -9 | hSpCas9 | negative selection | 1260768 | 159854803 | 159854826 | 1 | - | 26627737 | RPE1 | viability after 18 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | 0.46642077708929985 | [249] | [84,101] | 3 | hSpCas9 | negative selection | 1343082 | 159856056 | 159856079 | 1 | + | 26627737 | RPE1 | viability after 18 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | -3.7747584794695523 | [1091] | [36,4] | -9 | hSpCas9 | negative selection | 1343083 | 159854803 | 159854826 | 1 | - | 26627737 | HeLa | viability after 8 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | -0.18095753300721573 | [192] | [51,55,106] | -2 | hSpCas9 | negative selection | 1425397 | 159856056 | 159856079 | 1 | + | 26627737 | HeLa | viability after 8 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 1.3642438962763963 | [86] | [123,117,58] | 8 | hSpCas9 | negative selection | 1425398 | 159854803 | 159854826 | 1 | - | 26627737 | HeLa | viability after 12 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | -0.14568640408285405 | [192] | [63,100,47] | -1 | hSpCas9 | negative selection | 1507712 | 159856056 | 159856079 | 1 | + | 26627737 | HeLa | viability after 12 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 0.47514098382689607 | [86] | [93,51,4] | 4 | hSpCas9 | negative selection | 1507713 | 159854803 | 159854826 | 1 | - | 26627737 | HeLa | viability after 15 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | 0.06109362812478625 | [192] | [106,111,21] | 0 | hSpCas9 | negative selection | 1590027 | 159856056 | 159856079 | 1 | + | 26627737 | HeLa | viability after 15 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 0.6755684782797644 | [86] | [54,66,46] | 5 | hSpCas9 | negative selection | 1590028 | 159854803 | 159854826 | 1 | - | 26627737 | HeLa | viability after 18 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | 0.050334690714928576 | [192] | [67,95,21] | 0 | hSpCas9 | negative selection | 1672342 | 159856056 | 159856079 | 1 | + | 26627737 | HeLa | viability after 18 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 0.7976233840398308 | [86] | [42,59,46] | 6 | hSpCas9 | negative selection | 1672343 | 159854803 | 159854826 | 1 | - | 26627737 | HCT116 | viability after 6 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | -4.434510905133118 | [381] | [5,0] | -9 | hSpCas9 | negative selection | 1754657 | 159856056 | 159856079 | 1 | + | 26627737 | HCT116 | viability after 6 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 0.9375410858343534 | [244] | [134,39] | 5 | hSpCas9 | negative selection | 1754658 | 159854803 | 159854826 | 1 | - | 26627737 | HCT116 | viability after 8 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | 0.013792612451016484 | [166] | [101,93,82] | 0 | hSpCas9 | negative selection | 1836972 | 159856056 | 159856079 | 1 | + | 26627737 | HCT116 | viability after 8 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 5.607610284761608 | [0] | [31,46,1] | 9 | hSpCas9 | negative selection | 1836973 | 159854803 | 159854826 | 1 | - | 26627737 | HCT116 | viability after 9 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | -2.3550671472313747 | [381] | [10,26] | -9 | hSpCas9 | negative selection | 1919287 | 159856056 | 159856079 | 1 | + | 26627737 | HCT116 | viability after 9 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | -0.5403728026691152 | [244] | [6,74] | -4 | hSpCas9 | negative selection | 1919288 | 159854803 | 159854826 | 1 | - | 26627737 | HCT116 | viability after 12 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | -1.2344380049664514 | [166] | [19,19,72] | -8 | hSpCas9 | negative selection | 2001602 | 159856056 | 159856079 | 1 | + | 26627737 | HCT116 | viability after 12 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 6.885971394244812 | [0] | [58,113,14] | 9 | hSpCas9 | negative selection | 2001603 | 159854803 | 159854826 | 1 | - | 26627737 | HCT116 | viability after 15 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | -0.7481236372736078 | [166] | [53,65,50] | -6 | hSpCas9 | negative selection | 2083917 | 159856056 | 159856079 | 1 | + | 26627737 | HCT116 | viability after 15 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 4.742284986882398 | [0] | [12,31,0] | 9 | hSpCas9 | negative selection | 2083918 | 159854803 | 159854826 | 1 | - | 26627737 | HCT116 | viability after 18 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | -0.8032187724622253 | [166] | [24,78,31] | -6 | hSpCas9 | negative selection | 2166232 | 159856056 | 159856079 | 1 | + | 26627737 | HCT116 | viability after 18 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 6.227581463548022 | [0] | [3,80,19] | 9 | hSpCas9 | negative selection | 2166233 | 159855443 | 159855466 | 1 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GCTAATGATTGCAATGCCTCGGG | VSIG8 | ENSG00000243284 | 0.7678711943498902 | [19,85] | [4,35] | 3 | dCas9-VP64 | positive selection | 2398944 | 159855414 | 159855437 | 1 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGGAAAGATGGAGAAGACTGAGG | VSIG8 | ENSG00000243284 | 0.2794027995612651 | [449,11] | [110,5] | 1 | dCas9-VP64 | positive selection | 2398945 | 159855434 | 159855457 | 1 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGCAATGCCTCGGGGATGGAGGG | VSIG8 | ENSG00000243284 | 0.8595452810232616 | [12,56] | [15,10] | 3 | dCas9-VP64 | positive selection | 2398946 | 159855443 | 159855466 | 1 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GCTAATGATTGCAATGCCTCGGG | VSIG8 | ENSG00000243284 | -0.746217565319488 | [75,55] | [14,9] | -7 | dCas9-VP64 | positive selection | 2494199 | 159855414 | 159855437 | 1 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGGAAAGATGGAGAAGACTGAGG | VSIG8 | ENSG00000243284 | -0.5789753550569824 | [145,103] | [41,12] | -6 | dCas9-VP64 | positive selection | 2494200 | 159855434 | 159855457 | 1 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGCAATGCCTCGGGGATGGAGGG | VSIG8 | ENSG00000243284 | -0.2459568807961231 | [166,275] | [85,36] | -2 | dCas9-VP64 | positive selection | 2494201 | 159857788 | 159857811 | 1 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TGAGTGGTAGCTGTGCTGGGAGG | VSIG8 | ENSG00000243284 | 4.95672768530439 | [] | [] | 8 | hSpCas9 | negative selection | 3577972 | 159857788 | 159857811 | 1 | + | 26780180 | A375 | viability (Avana lentiGuide) | TGAGTGGTAGCTGTGCTGGGAGG | VSIG8 | ENSG00000243284 | -0.789390307454344 | [] | [] | -1 | hSpCas9 | negative selection | 3686631 | 159857788 | 159857811 | 1 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TGAGTGGTAGCTGTGCTGGGAGG | VSIG8 | ENSG00000243284 | 0.18166536164510555 | [5] | [5,5] | 5 | hSpCas9 | positive selection | 3795238 | 159857788 | 159857811 | 1 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TGAGTGGTAGCTGTGCTGGGAGG | VSIG8 | ENSG00000243284 | 0.07961696744365822 | [5] | [5,4] | 1 | hSpCas9 | positive selection | 3903845 | 159854885 | 159854908 | 1 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CACGTCCTCGGGGCCGCCGCAGG | VSIG8 | ENSG00000243284 | -0.23311050788917057 | [3] | [1,1] | -5 | hSpCas9 | positive selection | 4186661 | 159854821 | 159854844 | 1 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.0619786188088447 | [2] | [1,1] | -1 | hSpCas9 | positive selection | 4186662 | 159855193 | 159855216 | 1 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.2078173049782956 | [3] | [1,3] | 5 | hSpCas9 | positive selection | 4186663 | 159854911 | 159854934 | 1 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GAGGCGCGTACTTGCGGCGCAGG | VSIG8 | ENSG00000243284 | 0.12034424193338662 | [3] | [2,2] | 3 | hSpCas9 | positive selection | 4186664 | 159854885 | 159854908 | 1 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CACGTCCTCGGGGCCGCCGCAGG | VSIG8 | ENSG00000243284 | 0.03672796043648115 | [3] | [2,2,1,0] | 0 | hSpCas9 | positive selection | 4250683 | 159854821 | 159854844 | 1 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.8826790170410928 | [3] | [1,0,2,3] | 6 | hSpCas9 | positive selection | 4250684 | 159855193 | 159855216 | 1 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.15182778267325123 | [3] | [1,3,1,0] | 1 | hSpCas9 | positive selection | 4250685 | 159854911 | 159854934 | 1 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GAGGCGCGTACTTGCGGCGCAGG | VSIG8 | ENSG00000243284 | 0.6945998285166894 | [2] | [3,3,2,0] | 4 | hSpCas9 | positive selection | 4250686 | 159854821 | 159854844 | 1 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.09052084656109134 | [3] | [3,1] | -2 | hSpCas9 | positive selection | 4259523 | 159854901 | 159854924 | 1 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.17611799567448017 | [4] | [4,3] | 3 | hSpCas9 | positive selection | 4259524 | 159855193 | 159855216 | 1 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | -0.2475989682476022 | [1] | [0,0] | -5 | hSpCas9 | positive selection | 4259525 | 159855200 | 159855223 | 1 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.19626940371692742 | [2] | [1,2] | 4 | hSpCas9 | positive selection | 4323804 | 159857812 | 159857834 | 1 | + | 27760321 | OCIAML3 | viability | GTAAGACCCAGCTCGATAGGGG | VSIG8 | ENSG00000243284 | -0.825626346748715 | [569,478] | [174,302] | -6 | hSpCas9 | negative selection | 4453550 | 159857812 | 159857834 | 1 | + | 27760321 | OCIAML2 | viability | GTAAGACCCAGCTCGATAGGGG | VSIG8 | ENSG00000243284 | 0.13898845561778994 | [569,478] | [445,490] | 1 | hSpCas9 | negative selection | 4537013 | 159857812 | 159857834 | 1 | + | 27760321 | MV411 | viability | GTAAGACCCAGCTCGATAGGGG | VSIG8 | ENSG00000243284 | 0.020918996711542404 | [569,478] | [139,664] | 0 | hSpCas9 | negative selection | 4620476 | 159857812 | 159857834 | 1 | + | 27760321 | HL60 | viability | GTAAGACCCAGCTCGATAGGGG | VSIG8 | ENSG00000243284 | -0.2479070469347914 | [569,478] | [389,326] | -3 | hSpCas9 | negative selection | 4703939 | 159857812 | 159857834 | 1 | + | 27760321 | HT1080 | viability | GTAAGACCCAGCTCGATAGGGG | VSIG8 | ENSG00000243284 | 1.5428855103447123 | [478,373] | [443,550] | 8 | hSpCas9 | negative selection | 4787402 | 159857812 | 159857834 | 1 | + | 27760321 | HT29 | viability after 7 days | GTAAGACCCAGCTCGATAGGGG | VSIG8 | ENSG00000243284 | 0.24335545073145587 | [478,373] | [903,499,580] | 4 | hSpCas9 | negative selection | 4870865 | 159857812 | 159857834 | 1 | + | 27760321 | HT29 | viability after 25 days | GTAAGACCCAGCTCGATAGGGG | VSIG8 | ENSG00000243284 | 0.3246293810848315 | [478,373] | [499,651,693] | 3 | hSpCas9 | negative selection | 4954328 | 159857812 | 159857834 | 1 | + | 27760321 | HT29 | viability after 22 days | GTAAGACCCAGCTCGATAGGGG | VSIG8 | ENSG00000243284 | 0.22219558195530903 | [478,373] | [521,620,583] | 2 | hSpCas9 | negative selection | 5037791 | 159857812 | 159857834 | 1 | + | 27760321 | HT29 | viability after 19 days | GTAAGACCCAGCTCGATAGGGG | VSIG8 | ENSG00000243284 | 0.46919457932500397 | [478,373] | [973,658,432] | 4 | hSpCas9 | negative selection | 5121254 | 159857812 | 159857834 | 1 | + | 27760321 | HT29 | viability after 16 days | GTAAGACCCAGCTCGATAGGGG | VSIG8 | ENSG00000243284 | 0.6746047518504142 | [478,373] | [854,595,846] | 7 | hSpCas9 | negative selection | 5204717 | 159857812 | 159857834 | 1 | + | 27760321 | HT29 | viability after 13 days | GTAAGACCCAGCTCGATAGGGG | VSIG8 | ENSG00000243284 | 0.2153160325308503 | [478,373] | [649,480,590] | 2 | hSpCas9 | negative selection | 5288180 | 159857812 | 159857834 | 1 | + | 27760321 | HT29 | viability after 10 days | GTAAGACCCAGCTCGATAGGGG | VSIG8 | ENSG00000243284 | 0.2992157530541152 | [478,373] | [545,730,689] | 4 | hSpCas9 | negative selection | 5371643 | 159857812 | 159857834 | 1 | + | 27760321 | MOLM13 | viability | GTAAGACCCAGCTCGATAGGGG | VSIG8 | ENSG00000243284 | 0.07697392684852561 | [569,478] | [378,252] | 0 | hSpCas9 | negative selection | 5455106 | 159854837 | 159854860 | 1 | + | 27661255 | K562 | viability | GGAGGGGCCCGCTTCGCAGGCGG | VSIG8 | ENSG00000243284 | 0.050830532856487975 | [919,963] | [882,689] | 1 | dCas9-KRAB | negative selection | 5466558 | 159854861 | 159854884 | 1 | + | 27661255 | K562 | viability | GGCGGCGGTGCAGGGCGCCAGGG | VSIG8 | ENSG00000243284 | -0.25971501118288254 | [661,750] | [472,467] | -6 | dCas9-KRAB | negative selection | 5466559 | 159854424 | 159854447 | 1 | - | 27661255 | K562 | viability | GGTGTCCCCAGCCTAAGCAGAGG | VSIG8 | ENSG00000243284 | 0.29113238309504164 | [531,640] | [647,505] | 8 | dCas9-KRAB | negative selection | 5466560 | 159854463 | 159854486 | 1 | - | 27661255 | K562 | viability | GGAGGCTGAGTGTCCTAGAGCGG | VSIG8 | ENSG00000243284 | 0.06581145522580747 | [908,894] | [850,671] | 2 | dCas9-KRAB | negative selection | 5466561 | 159854821 | 159854844 | 1 | - | 27260156 | BXPC3 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.2251661354913707 | [611] | [698,627,756,938] | 5 | hSpCas9 | negative selection | 5531983 | 159854901 | 159854924 | 1 | - | 27260156 | BXPC3 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.0732919512314738 | [1244] | [1218,1232,1600,1454] | 1 | hSpCas9 | negative selection | 5531984 | 159855193 | 159855216 | 1 | - | 27260156 | BXPC3 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.44079620976368084 | [78] | [73,97,117,169] | 8 | hSpCas9 | negative selection | 5531985 | 159855200 | 159855223 | 1 | + | 27260156 | BXPC3 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.12385907454527689 | [257] | [235,217,251,290] | -3 | hSpCas9 | negative selection | 5596264 | 159854821 | 159854844 | 1 | - | 27260156 | A673 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.16704908212803532 | [611] | [897,723,778,913] | 4 | hSpCas9 | negative selection | 5653234 | 159854901 | 159854924 | 1 | - | 27260156 | A673 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.1689445285141542 | [1244] | [1968,1327,1749,1715] | 4 | hSpCas9 | negative selection | 5653235 | 159855193 | 159855216 | 1 | - | 27260156 | A673 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.36461667635936923 | [78] | [105,136,106,136] | 8 | hSpCas9 | negative selection | 5653236 | 159855200 | 159855223 | 1 | + | 27260156 | A673 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.26514420693607366 | [257] | [227,299,228,269] | -6 | hSpCas9 | negative selection | 5717515 | 159854821 | 159854844 | 1 | - | 27260156 | A375 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.36865906359826484 | [611] | [654,562,540,465] | -5 | hSpCas9 | negative selection | 5774485 | 159854901 | 159854924 | 1 | - | 27260156 | A375 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.07390577205703375 | [1244] | [1697,1826,1557,1124] | 1 | hSpCas9 | negative selection | 5774486 | 159855193 | 159855216 | 1 | - | 27260156 | A375 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.28425191227513924 | [78] | [115,121,40,164] | 4 | hSpCas9 | negative selection | 5774487 | 159855200 | 159855223 | 1 | + | 27260156 | A375 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.08089561034571413 | [257] | [174,336,449,193] | -1 | hSpCas9 | negative selection | 5838766 | 159854821 | 159854844 | 1 | - | 27260156 | COLO741 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.04969171322029009 | [611] | [896,756,631] | -1 | hSpCas9 | negative selection | 5895736 | 159854901 | 159854924 | 1 | - | 27260156 | COLO741 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.03757444170336899 | [1244] | [1959,1543,1432] | 0 | hSpCas9 | negative selection | 5895737 | 159855193 | 159855216 | 1 | - | 27260156 | COLO741 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.3916003404461934 | [78] | [124,175,97] | 7 | hSpCas9 | negative selection | 5895738 | 159855200 | 159855223 | 1 | + | 27260156 | COLO741 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.1404830801411302 | [257] | [416,400,281] | 3 | hSpCas9 | negative selection | 5960017 | 159854821 | 159854844 | 1 | - | 27260156 | CAL120 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.07479174524262916 | [611] | [984,646,578] | -1 | hSpCas9 | negative selection | 6016987 | 159854901 | 159854924 | 1 | - | 27260156 | CAL120 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.021944297408702074 | [1244] | [1606,1236,1873] | 0 | hSpCas9 | negative selection | 6016988 | 159855193 | 159855216 | 1 | - | 27260156 | CAL120 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 1.056808149357928 | [78] | [422,56,166] | 9 | hSpCas9 | negative selection | 6016989 | 159855200 | 159855223 | 1 | + | 27260156 | CAL120 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.07565651315050126 | [257] | [680,134,251] | 1 | hSpCas9 | negative selection | 6081268 | 159854821 | 159854844 | 1 | - | 27260156 | CADOES1 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.03515551814340928 | [611] | [584,479,466,694] | 0 | hSpCas9 | negative selection | 6138238 | 159854901 | 159854924 | 1 | - | 27260156 | CADOES1 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.10778424292921529 | [1244] | [1186,1192,1413,1194] | 1 | hSpCas9 | negative selection | 6138239 | 159855193 | 159855216 | 1 | - | 27260156 | CADOES1 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.04083052675006593 | [78] | [55,58,94,92] | 0 | hSpCas9 | negative selection | 6138240 | 159855200 | 159855223 | 1 | + | 27260156 | CADOES1 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.20396239996966448 | [257] | [309,145,216,157] | -4 | hSpCas9 | negative selection | 6202519 | 159854821 | 159854844 | 1 | - | 27260156 | EWS502 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.06530401884639925 | [611] | [668,647,672,725] | 1 | hSpCas9 | negative selection | 6259489 | 159854901 | 159854924 | 1 | - | 27260156 | EWS502 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.18132126591476494 | [1244] | [1216,1655,1450,1691] | 3 | hSpCas9 | negative selection | 6259490 | 159855193 | 159855216 | 1 | - | 27260156 | EWS502 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.37686136714726315 | [78] | [30,90,163,162] | 6 | hSpCas9 | negative selection | 6259491 | 159855200 | 159855223 | 1 | + | 27260156 | EWS502 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.4391250400254553 | [257] | [267,537,248,433] | 7 | hSpCas9 | negative selection | 6323770 | 159854821 | 159854844 | 1 | - | 27260156 | EW8 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.23350970726653703 | [611] | [652,713,466,524] | 4 | hSpCas9 | negative selection | 6380740 | 159854901 | 159854924 | 1 | - | 27260156 | EW8 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.32116869419885896 | [1244] | [1621,1187,1234,1037] | 6 | hSpCas9 | negative selection | 6380741 | 159855193 | 159855216 | 1 | - | 27260156 | EW8 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 1.1326559490775514 | [78] | [275,121,75,112] | 9 | hSpCas9 | negative selection | 6380742 | 159855200 | 159855223 | 1 | + | 27260156 | EW8 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.03625496910219628 | [257] | [220,237,123,289] | 0 | hSpCas9 | negative selection | 6445021 | 159854821 | 159854844 | 1 | - | 27260156 | CORL105 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.22813203296069456 | [611] | [797,869,948,754] | 4 | hSpCas9 | negative selection | 6501991 | 159854901 | 159854924 | 1 | - | 27260156 | CORL105 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.2599891627331259 | [1244] | [1704,1678,2050,1593] | 5 | hSpCas9 | negative selection | 6501992 | 159855193 | 159855216 | 1 | - | 27260156 | CORL105 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.6276752258538472 | [78] | [117,97,134,218] | 9 | hSpCas9 | negative selection | 6501993 | 159855200 | 159855223 | 1 | + | 27260156 | CORL105 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.21516620174667744 | [257] | [533,226,429,232] | 4 | hSpCas9 | negative selection | 6566272 | 159854821 | 159854844 | 1 | - | 27260156 | HS294T | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.2939983210407297 | [611] | [265,226,345,331] | 4 | hSpCas9 | negative selection | 6623242 | 159854901 | 159854924 | 1 | - | 27260156 | HS294T | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.2870932533899355 | [1244] | [525,594,550,699] | 4 | hSpCas9 | negative selection | 6623243 | 159855193 | 159855216 | 1 | - | 27260156 | HS294T | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.36894812425687906 | [78] | [34,34,39,49] | 5 | hSpCas9 | negative selection | 6623244 | 159855200 | 159855223 | 1 | + | 27260156 | HS294T | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.33158010821533956 | [257] | [92,62,70,90] | -5 | hSpCas9 | negative selection | 6687523 | 159854821 | 159854844 | 1 | - | 27260156 | HCC44 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.13283967947113612 | [611] | [682,677,1109,627] | 2 | hSpCas9 | negative selection | 6744493 | 159854901 | 159854924 | 1 | - | 27260156 | HCC44 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.03550973478427455 | [1244] | [1674,1353,1665,1147] | 0 | hSpCas9 | negative selection | 6744494 | 159855193 | 159855216 | 1 | - | 27260156 | HCC44 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.5545706775352852 | [78] | [263,89,164,31] | 8 | hSpCas9 | negative selection | 6744495 | 159855200 | 159855223 | 1 | + | 27260156 | HCC44 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.35596483072097507 | [257] | [267,149,276,237] | -5 | hSpCas9 | negative selection | 6808774 | 159854821 | 159854844 | 1 | - | 27260156 | G402 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.1315476448854142 | [611] | [778,1038,846,620] | 1 | hSpCas9 | negative selection | 6865744 | 159854901 | 159854924 | 1 | - | 27260156 | G402 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.20740770505338668 | [1244] | [1794,2175,1616,1465] | 2 | hSpCas9 | negative selection | 6865745 | 159855193 | 159855216 | 1 | - | 27260156 | G402 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.3086208595927795 | [78] | [145,79,161,91] | 4 | hSpCas9 | negative selection | 6865746 | 159855200 | 159855223 | 1 | + | 27260156 | G402 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.4119585276718956 | [257] | [616,256,484,337] | 5 | hSpCas9 | negative selection | 6930025 | 159854821 | 159854844 | 1 | - | 27260156 | L33 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.2599302945281258 | [611] | [652,290,468,822] | 5 | hSpCas9 | negative selection | 6986995 | 159854901 | 159854924 | 1 | - | 27260156 | L33 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.24515764332479661 | [1244] | [1506,615,959,1364] | 5 | hSpCas9 | negative selection | 6986996 | 159855193 | 159855216 | 1 | - | 27260156 | L33 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.6584985166832924 | [78] | [130,40,81,136] | 9 | hSpCas9 | negative selection | 6986997 | 159855200 | 159855223 | 1 | + | 27260156 | L33 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.30723400900021014 | [257] | [190,64,163,223] | -6 | hSpCas9 | negative selection | 7051276 | 159854821 | 159854844 | 1 | - | 27260156 | K562 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.36511636567892086 | [611] | [503,1165,343,779] | 4 | hSpCas9 | negative selection | 7108246 | 159854901 | 159854924 | 1 | - | 27260156 | K562 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.37201309791072057 | [1244] | [1893,1466,1082,1321] | 5 | hSpCas9 | negative selection | 7108247 | 159855193 | 159855216 | 1 | - | 27260156 | K562 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.4248076243113985 | [78] | [138,68,147,29] | 5 | hSpCas9 | negative selection | 7108248 | 159855200 | 159855223 | 1 | + | 27260156 | K562 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.20097950400340148 | [257] | [173,163,587,128] | 2 | hSpCas9 | negative selection | 7172527 | 159854821 | 159854844 | 1 | - | 27260156 | HT29 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.3183344374438147 | [611] | [1081,813,766,1029] | 6 | hSpCas9 | negative selection | 7229497 | 159854901 | 159854924 | 1 | - | 27260156 | HT29 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.030821699821469206 | [1244] | [1669,1454,1486,1560] | 0 | hSpCas9 | negative selection | 7229498 | 159855193 | 159855216 | 1 | - | 27260156 | HT29 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.1858769980543462 | [78] | [171,73,118,76] | 3 | hSpCas9 | negative selection | 7229499 | 159855200 | 159855223 | 1 | + | 27260156 | HT29 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.10502014754255162 | [257] | [552,247,291,270] | 2 | hSpCas9 | negative selection | 7293778 | 159854821 | 159854844 | 1 | - | 27260156 | MHHES1 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.223235246508302 | [611] | [819,1038,758,644] | 4 | hSpCas9 | negative selection | 7350748 | 159854901 | 159854924 | 1 | - | 27260156 | MHHES1 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.2729124762782231 | [1244] | [2140,2009,1390,1358] | 5 | hSpCas9 | negative selection | 7350749 | 159855193 | 159855216 | 1 | - | 27260156 | MHHES1 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.23226375707266733 | [78] | [157,88,122,60] | 4 | hSpCas9 | negative selection | 7350750 | 159855200 | 159855223 | 1 | + | 27260156 | MHHES1 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.35867580960721845 | [257] | [286,353,182,121] | -6 | hSpCas9 | negative selection | 7415029 | 159854821 | 159854844 | 1 | - | 27260156 | MEWO | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.11594321681869063 | [611] | [659,412,537] | -3 | hSpCas9 | negative selection | 7471999 | 159854901 | 159854924 | 1 | - | 27260156 | MEWO | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.1586900932280011 | [1244] | [1629,1140,1193] | 3 | hSpCas9 | negative selection | 7472000 | 159855193 | 159855216 | 1 | - | 27260156 | MEWO | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.15304272083669934 | [78] | [93,43,110] | 3 | hSpCas9 | negative selection | 7472001 | 159855200 | 159855223 | 1 | + | 27260156 | MEWO | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.2235227288186773 | [257] | [405,172,290] | 5 | hSpCas9 | negative selection | 7536280 | 159854821 | 159854844 | 1 | - | 27260156 | LNCAPCLONEFGC | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.2150987164058172 | [611] | [520,374,571,461] | -3 | hSpCas9 | negative selection | 7593250 | 159854901 | 159854924 | 1 | - | 27260156 | LNCAPCLONEFGC | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.07109659862794682 | [1244] | [1114,1054,1250,1336] | 1 | hSpCas9 | negative selection | 7593251 | 159855193 | 159855216 | 1 | - | 27260156 | LNCAPCLONEFGC | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 1.0189404303908938 | [78] | [186,144,143,102] | 9 | hSpCas9 | negative selection | 7593252 | 159855200 | 159855223 | 1 | + | 27260156 | LNCAPCLONEFGC | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.22292393772251462 | [257] | [391,207,219,264] | 3 | hSpCas9 | negative selection | 7657531 | 159854821 | 159854844 | 1 | - | 27260156 | PANC0327 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.22751515661075167 | [611] | [530,384,520,435] | -3 | hSpCas9 | negative selection | 7714501 | 159854901 | 159854924 | 1 | - | 27260156 | PANC0327 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.258056604835774 | [1244] | [1486,1135,1587,1116] | 4 | hSpCas9 | negative selection | 7714502 | 159855193 | 159855216 | 1 | - | 27260156 | PANC0327 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.7464392024196485 | [78] | [195,57,108,121] | 9 | hSpCas9 | negative selection | 7714503 | 159855200 | 159855223 | 1 | + | 27260156 | PANC0327 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.5996385287525308 | [257] | [227,137,165,80] | -7 | hSpCas9 | negative selection | 7778782 | 159854821 | 159854844 | 1 | - | 27260156 | NCIH2009 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.1127747321792385 | [611] | [1341,906,605] | 1 | hSpCas9 | negative selection | 7835752 | 159854901 | 159854924 | 1 | - | 27260156 | NCIH2009 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | -0.021652196899990317 | [1244] | [2079,1777,1350] | 0 | hSpCas9 | negative selection | 7835753 | 159855193 | 159855216 | 1 | - | 27260156 | NCIH2009 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.7443892067361522 | [78] | [319,135,125] | 8 | hSpCas9 | negative selection | 7835754 | 159855200 | 159855223 | 1 | + | 27260156 | NCIH2009 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.1460121782892294 | [257] | [363,342,276] | -2 | hSpCas9 | negative selection | 7900033 | 159854821 | 159854844 | 1 | - | 27260156 | NCIH1373 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.33841116276340494 | [611] | [852,942,833,215] | 3 | hSpCas9 | negative selection | 7957003 | 159854901 | 159854924 | 1 | - | 27260156 | NCIH1373 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.11562772210983985 | [1244] | [1714,1616,1502,316] | 1 | hSpCas9 | negative selection | 7957004 | 159855193 | 159855216 | 1 | - | 27260156 | NCIH1373 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 1.0458186231688007 | [78] | [61,154,220,73] | 9 | hSpCas9 | negative selection | 7957005 | 159855200 | 159855223 | 1 | + | 27260156 | NCIH1373 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.06434566367144434 | [257] | [373,128,273,123] | 0 | hSpCas9 | negative selection | 8021284 | 159854821 | 159854844 | 1 | - | 27260156 | PATU8902 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.2631115314408761 | [611] | [972,1096,270,591] | -3 | hSpCas9 | negative selection | 8078254 | 159854901 | 159854924 | 1 | - | 27260156 | PATU8902 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.30159836970445264 | [1244] | [2797,2404,1388,2123] | 3 | hSpCas9 | negative selection | 8078255 | 159855193 | 159855216 | 1 | - | 27260156 | PATU8902 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.8009677612820352 | [78] | [130,73,313,217] | 8 | hSpCas9 | negative selection | 8078256 | 159855200 | 159855223 | 1 | + | 27260156 | PATU8902 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.46131780279513046 | [257] | [218,393,485,933] | 5 | hSpCas9 | negative selection | 8142535 | 159854821 | 159854844 | 1 | - | 27260156 | PANC1 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.4425638511066296 | [611] | [628,781,944,536] | 7 | hSpCas9 | negative selection | 8199505 | 159854901 | 159854924 | 1 | - | 27260156 | PANC1 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.5104256265667519 | [1244] | [1437,1641,1613,1417] | 7 | hSpCas9 | negative selection | 8199506 | 159855193 | 159855216 | 1 | - | 27260156 | PANC1 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.8069077821060733 | [78] | [125,89,132,117] | 9 | hSpCas9 | negative selection | 8199507 | 159855200 | 159855223 | 1 | + | 27260156 | PANC1 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.0695286065842341 | [257] | [216,257,258,202] | 1 | hSpCas9 | negative selection | 8263786 | 159854821 | 159854844 | 1 | - | 27260156 | PANC0813 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.45114124675011164 | [611] | [1061,1056,1106,725] | 7 | hSpCas9 | negative selection | 8320756 | 159854901 | 159854924 | 1 | - | 27260156 | PANC0813 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.29200045589199086 | [1244] | [1654,2118,1695,1681] | 5 | hSpCas9 | negative selection | 8320757 | 159855193 | 159855216 | 1 | - | 27260156 | PANC0813 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.676090152820207 | [78] | [161,122,71,231] | 9 | hSpCas9 | negative selection | 8320758 | 159855200 | 159855223 | 1 | + | 27260156 | PANC0813 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.0399866788547828 | [257] | [368,283,320,278] | 0 | hSpCas9 | negative selection | 8385037 | 159854821 | 159854844 | 1 | - | 27260156 | RDES | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.3057164117795815 | [611] | [581,464,524,713] | -5 | hSpCas9 | negative selection | 8442007 | 159854901 | 159854924 | 1 | - | 27260156 | RDES | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.19935340808514534 | [1244] | [1431,1514,1738,1945] | 3 | hSpCas9 | negative selection | 8442008 | 159855193 | 159855216 | 1 | - | 27260156 | RDES | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.8890625441395388 | [78] | [89,164,184,260] | 9 | hSpCas9 | negative selection | 8442009 | 159855200 | 159855223 | 1 | + | 27260156 | RDES | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.07028121951164834 | [257] | [250,232,299,361] | -1 | hSpCas9 | negative selection | 8506288 | 159854821 | 159854844 | 1 | - | 27260156 | PC3 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.013244595300064 | [611] | [297,566,1085,749] | 0 | hSpCas9 | negative selection | 8563258 | 159854901 | 159854924 | 1 | - | 27260156 | PC3 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | -0.05301599661389589 | [1244] | [702,947,2235,1435] | -1 | hSpCas9 | negative selection | 8563259 | 159855193 | 159855216 | 1 | - | 27260156 | PC3 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.3569625873945208 | [78] | [74,74,245,63] | 7 | hSpCas9 | negative selection | 8563260 | 159855200 | 159855223 | 1 | + | 27260156 | PC3 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.26001853939643493 | [257] | [129,186,430,213] | -5 | hSpCas9 | negative selection | 8627539 | 159854821 | 159854844 | 1 | - | 27260156 | PATU8988T | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.11820537627611533 | [611] | [550,542,600,477] | -2 | hSpCas9 | negative selection | 8684509 | 159854901 | 159854924 | 1 | - | 27260156 | PATU8988T | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.28461150649026457 | [1244] | [1313,1661,1263,1657] | 5 | hSpCas9 | negative selection | 8684510 | 159855193 | 159855216 | 1 | - | 27260156 | PATU8988T | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.27403104842859527 | [78] | [59,87,130,88] | 5 | hSpCas9 | negative selection | 8684511 | 159855200 | 159855223 | 1 | + | 27260156 | PATU8988T | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.07824222610671527 | [257] | [226,251,201,380] | 1 | hSpCas9 | negative selection | 8748790 | 159854821 | 159854844 | 1 | - | 27260156 | T47D | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.27321784259103643 | [611] | [558,586,668,541] | -5 | hSpCas9 | negative selection | 8805760 | 159854901 | 159854924 | 1 | - | 27260156 | T47D | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.13723954455908283 | [1244] | [1778,1368,1627,1624] | 3 | hSpCas9 | negative selection | 8805761 | 159855193 | 159855216 | 1 | - | 27260156 | T47D | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.3740044419154196 | [78] | [111,120,119,123] | 7 | hSpCas9 | negative selection | 8805762 | 159855200 | 159855223 | 1 | + | 27260156 | T47D | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.08084657939019291 | [257] | [342,262,347,321] | 1 | hSpCas9 | negative selection | 8870041 | 159854821 | 159854844 | 1 | - | 27260156 | SU8686 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.3926830855192152 | [611] | [581,703,861,1123] | 6 | hSpCas9 | negative selection | 8927011 | 159854901 | 159854924 | 1 | - | 27260156 | SU8686 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.19077728323716214 | [1244] | [1154,1273,1432,1887] | 3 | hSpCas9 | negative selection | 8927012 | 159855193 | 159855216 | 1 | - | 27260156 | SU8686 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.5414751933220372 | [78] | [76,135,85,164] | 8 | hSpCas9 | negative selection | 8927013 | 159855200 | 159855223 | 1 | + | 27260156 | SU8686 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.07033276775096864 | [257] | [186,254,377,265] | 1 | hSpCas9 | negative selection | 8991292 | 159854821 | 159854844 | 1 | - | 27260156 | SKES1 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | 0.13199677858677755 | [611] | [686,816,703,500] | 3 | hSpCas9 | negative selection | 9048262 | 159854901 | 159854924 | 1 | - | 27260156 | SKES1 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.10815653920309254 | [1244] | [1442,1543,1315,1104] | 2 | hSpCas9 | negative selection | 9048263 | 159855193 | 159855216 | 1 | - | 27260156 | SKES1 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.19589614480309026 | [78] | [64,139,99,60] | 4 | hSpCas9 | negative selection | 9048264 | 159855200 | 159855223 | 1 | + | 27260156 | SKES1 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.08083045459097227 | [257] | [271,206,275,217] | -2 | hSpCas9 | negative selection | 9112543 | 159854821 | 159854844 | 1 | - | 27260156 | TOV112D | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.03338786979809305 | [611] | [512,969,512,485] | 0 | hSpCas9 | negative selection | 9169513 | 159854901 | 159854924 | 1 | - | 27260156 | TOV112D | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.206955449102332 | [1244] | [1724,1785,1200,1159] | 4 | hSpCas9 | negative selection | 9169514 | 159855193 | 159855216 | 1 | - | 27260156 | TOV112D | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.7525126349970104 | [78] | [185,163,98,96] | 9 | hSpCas9 | negative selection | 9169515 | 159855200 | 159855223 | 1 | + | 27260156 | TOV112D | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.20995604897374642 | [257] | [182,302,256,167] | -4 | hSpCas9 | negative selection | 9233794 | 159854821 | 159854844 | 1 | - | 27260156 | TC71 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.0023279940244841923 | [611] | [701,608,690,612] | 0 | hSpCas9 | negative selection | 9290764 | 159854901 | 159854924 | 1 | - | 27260156 | TC71 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | 0.06719790957072691 | [1244] | [1328,1328,1401,1542] | 1 | hSpCas9 | negative selection | 9290765 | 159855193 | 159855216 | 1 | - | 27260156 | TC71 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.230246499708747 | [78] | [82,148,54,112] | 5 | hSpCas9 | negative selection | 9290766 | 159855200 | 159855223 | 1 | + | 27260156 | TC71 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | -0.5860776953717859 | [257] | [123,208,170,237] | -9 | hSpCas9 | negative selection | 9355045 | 159854821 | 159854844 | 1 | - | 27260156 | TC32 | viability | CCCCTCCCCGGTCTACGTCAAGG | VSIG8 | ENSG00000243284 | -0.4051761040470323 | [611] | [295,408,573,485] | -6 | hSpCas9 | negative selection | 9412015 | 159854901 | 159854924 | 1 | - | 27260156 | TC32 | viability | AAGTACGCGCCTCCCCCCTGCGG | VSIG8 | ENSG00000243284 | -0.07163835026432297 | [1244] | [982,935,1531,1088] | -1 | hSpCas9 | negative selection | 9412016 | 159855193 | 159855216 | 1 | - | 27260156 | TC32 | viability | CGCTGCAGGGTCGCCGACCCAGG | VSIG8 | ENSG00000243284 | 0.36399639047307675 | [78] | [65,52,180,112] | 6 | hSpCas9 | negative selection | 9412017 | 159855200 | 159855223 | 1 | + | 27260156 | TC32 | viability | CGGCGACCCTGCAGCGGTCCCGG | VSIG8 | ENSG00000243284 | 0.15624858817153875 | [257] | [195,262,209,403] | 3 | hSpCas9 | negative selection | 9476296 | 159854803 | 159854826 | 1 | - | 27869803 | HPAFII | viability after 27 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | 0.43623958778366223 | [119] | [38,123,NaN] | 3 | hSpCas9 | negative selection | 9529854 | 159856056 | 159856079 | 1 | + | 27869803 | HPAFII | viability after 27 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 1.443901289491729 | [59] | [159,23,NaN] | 9 | hSpCas9 | negative selection | 9529855 | 159854803 | 159854826 | 1 | - | 27869803 | HPAFII | viability after 15 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | -0.012379101613385624 | [119] | [117,133,NaN] | 0 | hSpCas9 | negative selection | 9612303 | 159856056 | 159856079 | 1 | + | 27869803 | HPAFII | viability after 15 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 0.9333479134485787 | [59] | [243,47,NaN] | 8 | hSpCas9 | negative selection | 9612304 | 159854803 | 159854826 | 1 | - | 27869803 | ASPC1 | viability after 36 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | 0.4774980741130095 | [299] | [297,153,30] | 5 | hSpCas9 | negative selection | 9694752 | 159856056 | 159856079 | 1 | + | 27869803 | ASPC1 | viability after 36 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | -0.9759442798039697 | [238] | [23,103,5] | -7 | hSpCas9 | negative selection | 9694753 | 159854803 | 159854826 | 1 | - | 27869803 | PATU8988S | viability after 35 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | -0.28264516115122307 | [256] | [124,44,NaN] | -3 | hSpCas9 | negative selection | 9777201 | 159856056 | 159856079 | 1 | + | 27869803 | PATU8988S | viability after 35 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 0.8026103175275248 | [130] | [103,79,NaN] | 8 | hSpCas9 | negative selection | 9777202 | 159854803 | 159854826 | 1 | - | 27869803 | PATU8988S | viability after 31 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | 0.06722366316619266 | [256] | [131,75,NaN] | 0 | hSpCas9 | negative selection | 9859650 | 159856056 | 159856079 | 1 | + | 27869803 | PATU8988S | viability after 31 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | -0.28877810323131614 | [130] | [40,44,NaN] | -3 | hSpCas9 | negative selection | 9859651 | 159854803 | 159854826 | 1 | - | 27869803 | HPAFII | viability after 35 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | 0.9565840088800855 | [119] | [28,217,NaN] | 6 | hSpCas9 | negative selection | 9942099 | 159856056 | 159856079 | 1 | + | 27869803 | HPAFII | viability after 35 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 2.825166725475193 | [59] | [393,13,NaN] | 9 | hSpCas9 | negative selection | 9942100 | 159854803 | 159854826 | 1 | - | 27869803 | HPAFII | viability after 31 days | CAAGGTCAAGAGCGCGGAGCCGG | VSIG8 | ENSG00000243284 | 0.7287661564459469 | [119] | [46,181,NaN] | 5 | hSpCas9 | negative selection | 10024548 | 159856056 | 159856079 | 1 | + | 27869803 | HPAFII | viability after 31 days | GATGATCACGCCTATACGCCGGG | VSIG8 | ENSG00000243284 | 2.4811242683444816 | [59] | [310,53,NaN] | 9 | hSpCas9 | negative selection | 10024549 | 159856539 | 159856562 | 1 | - | 28162770 | P31FUJ | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | -0.020498600701514436 | [491] | [569] | 0 | hSpCas9 | negative selection | 10264034 | 159855928 | 159855951 | 1 | - | 28162770 | P31FUJ | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | 0.4870898763928862 | [288] | [475] | 5 | hSpCas9 | negative selection | 10264035 | 159856592 | 159856615 | 1 | - | 28162770 | P31FUJ | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | 0.05990755583908092 | [408] | [500] | 0 | hSpCas9 | negative selection | 10264036 | 159856572 | 159856595 | 1 | - | 28162770 | P31FUJ | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 0.8201466755345805 | [213] | [443] | 8 | hSpCas9 | negative selection | 10264037 | 159856539 | 159856562 | 1 | - | 28162770 | TF1 | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | NaN | [NaN] | [567] | 1 | hSpCas9 | negative selection | 10433400 | 159855928 | 159855951 | 1 | - | 28162770 | TF1 | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | NaN | [NaN] | [357] | 1 | hSpCas9 | negative selection | 10433401 | 159856592 | 159856615 | 1 | - | 28162770 | TF1 | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | NaN | [NaN] | [464] | 1 | hSpCas9 | negative selection | 10433402 | 159856572 | 159856595 | 1 | - | 28162770 | TF1 | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | NaN | [NaN] | [307] | 1 | hSpCas9 | negative selection | 10433403 | 159856539 | 159856562 | 1 | - | 28162770 | SKM1 | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | 0.7211406270045235 | [69] | [203] | 7 | hSpCas9 | negative selection | 10602766 | 159855928 | 159855951 | 1 | - | 28162770 | SKM1 | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | 0.4371906415173942 | [93] | [224] | 4 | hSpCas9 | negative selection | 10602767 | 159856592 | 159856615 | 1 | - | 28162770 | SKM1 | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | -0.5404313407507841 | [115] | [140] | -4 | hSpCas9 | negative selection | 10602768 | 159856572 | 159856595 | 1 | - | 28162770 | SKM1 | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 1.0186904079097112 | [54] | [196] | 8 | hSpCas9 | negative selection | 10602769 | 159856539 | 159856562 | 1 | - | 28162770 | SKM1 | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | 0.7211406270045235 | [69] | [203] | 7 | hSpCas9 | negative selection | 10772132 | 159855928 | 159855951 | 1 | - | 28162770 | SKM1 | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | 0.4371906415173942 | [93] | [224] | 4 | hSpCas9 | negative selection | 10772133 | 159856592 | 159856615 | 1 | - | 28162770 | SKM1 | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | -0.5404313407507841 | [115] | [140] | -4 | hSpCas9 | negative selection | 10772134 | 159856572 | 159856595 | 1 | - | 28162770 | SKM1 | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 1.0186904079097112 | [54] | [196] | 8 | hSpCas9 | negative selection | 10772135 | 159856539 | 159856562 | 1 | - | 28162770 | PL21 | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | 0.321276051990955 | [273] | [148] | 3 | hSpCas9 | negative selection | 10941498 | 159855928 | 159855951 | 1 | - | 28162770 | PL21 | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | -1.3347822037322405 | [254] | [43] | -7 | hSpCas9 | negative selection | 10941499 | 159856592 | 159856615 | 1 | - | 28162770 | PL21 | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | 0.5806198917317953 | [337] | [219] | 5 | hSpCas9 | negative selection | 10941500 | 159856572 | 159856595 | 1 | - | 28162770 | PL21 | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 0.21573646954033882 | [183] | [92] | 2 | hSpCas9 | negative selection | 10941501 | 159856539 | 159856562 | 1 | - | 28162770 | P31FUJ | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | -0.020498600701514436 | [491] | [569] | 0 | hSpCas9 | negative selection | 11110864 | 159855928 | 159855951 | 1 | - | 28162770 | P31FUJ | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | 0.4870898763928862 | [288] | [475] | 5 | hSpCas9 | negative selection | 11110865 | 159856592 | 159856615 | 1 | - | 28162770 | P31FUJ | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | 0.05990755583908092 | [408] | [500] | 0 | hSpCas9 | negative selection | 11110866 | 159856572 | 159856595 | 1 | - | 28162770 | P31FUJ | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 0.8201466755345805 | [213] | [443] | 8 | hSpCas9 | negative selection | 11110867 | 159856539 | 159856562 | 1 | - | 28162770 | OCIAML5 | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | -0.2053750803911345 | [243] | [381] | -1 | hSpCas9 | negative selection | 11280230 | 159855928 | 159855951 | 1 | - | 28162770 | OCIAML5 | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | -0.7882906604306823 | [176] | [184] | -5 | hSpCas9 | negative selection | 11280231 | 159856592 | 159856615 | 1 | - | 28162770 | OCIAML5 | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | 0.17091199291409498 | [217] | [442] | 1 | hSpCas9 | negative selection | 11280232 | 159856572 | 159856595 | 1 | - | 28162770 | OCIAML5 | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 0.022402547052144117 | [155] | [285] | 0 | hSpCas9 | negative selection | 11280233 | 159856539 | 159856562 | 1 | - | 28162770 | EOL1 | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | -0.6090463380602172 | [468] | [161] | -4 | hSpCas9 | negative selection | 11449596 | 159855928 | 159855951 | 1 | - | 28162770 | EOL1 | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | 0.5881991609370009 | [552] | [437] | 5 | hSpCas9 | negative selection | 11449597 | 159856592 | 159856615 | 1 | - | 28162770 | EOL1 | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | 0.10951665323729709 | [423] | [240] | 1 | hSpCas9 | negative selection | 11449598 | 159856572 | 159856595 | 1 | - | 28162770 | EOL1 | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 0.25753105496689277 | [207] | [130] | 2 | hSpCas9 | negative selection | 11449599 | 159856539 | 159856562 | 1 | - | 28162770 | MOLM13 | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | -0.09027305983286216 | [479] | [325] | 0 | hSpCas9 | negative selection | 11618962 | 159855928 | 159855951 | 1 | - | 28162770 | MOLM13 | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | 1.5498582283308597 | [324] | [687] | 9 | hSpCas9 | negative selection | 11618963 | 159856592 | 159856615 | 1 | - | 28162770 | MOLM13 | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | -0.01045069964278289 | [527] | [378] | 0 | hSpCas9 | negative selection | 11618964 | 159856572 | 159856595 | 1 | - | 28162770 | MOLM13 | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 1.1145525819379076 | [266] | [417] | 8 | hSpCas9 | negative selection | 11618965 | 159856539 | 159856562 | 1 | - | 28162770 | HEL | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | -0.49272458529476176 | [423] | [192] | -3 | hSpCas9 | negative selection | 11788328 | 159855928 | 159855951 | 1 | - | 28162770 | HEL | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | 0.4712583640560032 | [347] | [308] | 4 | hSpCas9 | negative selection | 11788329 | 159856592 | 159856615 | 1 | - | 28162770 | HEL | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | -0.26104585274034 | [405] | [216] | -2 | hSpCas9 | negative selection | 11788330 | 159856572 | 159856595 | 1 | - | 28162770 | HEL | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | -0.1433635408286506 | [218] | [126] | -1 | hSpCas9 | negative selection | 11788331 | 159856539 | 159856562 | 1 | - | 28162770 | MV411 | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | 0.05479247284037947 | [335] | [293] | 0 | hSpCas9 | negative selection | 11957694 | 159855928 | 159855951 | 1 | - | 28162770 | MV411 | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | 0.7637834394295412 | [243] | [348] | 7 | hSpCas9 | negative selection | 11957695 | 159856592 | 159856615 | 1 | - | 28162770 | MV411 | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | 0.595360854203082 | [285] | [363] | 5 | hSpCas9 | negative selection | 11957696 | 159856572 | 159856595 | 1 | - | 28162770 | MV411 | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 1.2147713618624532 | [133] | [261] | 9 | hSpCas9 | negative selection | 11957697 | 159856539 | 159856562 | 1 | - | 28162770 | MONOMAC1 | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | 0.040826983039334075 | [211] | [249] | 0 | hSpCas9 | negative selection | 12127060 | 159855928 | 159855951 | 1 | - | 28162770 | MONOMAC1 | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | -0.1466633245444342 | [196] | [203] | -1 | hSpCas9 | negative selection | 12127061 | 159856592 | 159856615 | 1 | - | 28162770 | MONOMAC1 | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | 0.20615440937118168 | [213] | [282] | 2 | hSpCas9 | negative selection | 12127062 | 159856572 | 159856595 | 1 | - | 28162770 | MONOMAC1 | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 0.5701289848823514 | [103] | [176] | 5 | hSpCas9 | negative selection | 12127063 | 159856539 | 159856562 | 1 | - | 28162770 | OCIAML2 | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | 0.5044032592412637 | [50] | [400] | 5 | hSpCas9 | negative selection | 12296426 | 159855928 | 159855951 | 1 | - | 28162770 | OCIAML2 | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | 0.46348223910138164 | [55] | [427] | 4 | hSpCas9 | negative selection | 12296427 | 159856592 | 159856615 | 1 | - | 28162770 | OCIAML2 | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | 0.08296850456965987 | [61] | [363] | 0 | hSpCas9 | negative selection | 12296428 | 159856572 | 159856595 | 1 | - | 28162770 | OCIAML2 | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | -0.004966252893349399 | [41] | [231] | 0 | hSpCas9 | negative selection | 12296429 | 159856539 | 159856562 | 1 | - | 28162770 | OCIAML3 | viability | GGGCTACAGTGTTTGTGTGGTGG | VSIG8 | ENSG00000243284 | 0.6203586404733669 | [102] | [477] | 5 | hSpCas9 | negative selection | 12465792 | 159855928 | 159855951 | 1 | - | 28162770 | OCIAML3 | viability | GCCTTCGGCTACGGCAACGGCGG | VSIG8 | ENSG00000243284 | 0.49127754762080644 | [77] | [330] | 4 | hSpCas9 | negative selection | 12465793 | 159856592 | 159856615 | 1 | - | 28162770 | OCIAML3 | viability | GATATCTCCAGAGCAGATGATGG | VSIG8 | ENSG00000243284 | -0.20555492663628072 | [88] | [232] | -2 | hSpCas9 | negative selection | 12465794 | 159856572 | 159856595 | 1 | - | 28162770 | OCIAML3 | viability | TGGGCTGTATCAGTGCACAGTGG | VSIG8 | ENSG00000243284 | 0.2967632899210784 | [47] | [177] | 3 | hSpCas9 | negative selection | 12465795 |