| 1730896 | 1730919 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Jiyoye | viability | GGACAGGCTCCCCATACAGGCGG | WDR81 | ENSG00000276021 | 0.4071753815058735 | [68] | [68] | 3 | hSpCas9 | negative selection | 181530 | 1736080 | 1736103 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Jiyoye | viability | GCCAGGGCACGGACAAGCCCAGG | WDR81 | ENSG00000276021 | 1.5175993711995237 | [43] | [94] | 8 | hSpCas9 | negative selection | 181531 | 1732785 | 1732808 | CHR_HSCHR17_1_CTG2 | + | 26472758 | Jiyoye | viability | GAAGGTGTTCACCCTGGAGATGG | WDR81 | ENSG00000276021 | 0.004628826410226383 | [114] | [86] | 0 | hSpCas9 | negative selection | 181532 | 1730407 | 1730430 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Jiyoye | viability | CGAGCTTGGCAGACAGCCAGCGG | WDR81 | ENSG00000276021 | 1.73367620618306 | [62] | [157] | 8 | hSpCas9 | negative selection | 181533 | 1730774 | 1730797 | CHR_HSCHR17_1_CTG2 | + | 26472758 | Jiyoye | viability | CAGCAGTTCACAGTGAGCAGTGG | WDR81 | ENSG00000276021 | -1.0872748263098404 | [416] | [147] | -6 | hSpCas9 | negative selection | 181534 | 1730804 | 1730827 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Jiyoye | viability | ATGTTGCCGGCGCTCAGCGGTGG | WDR81 | ENSG00000276021 | 0.022511531270548613 | [46] | [35] | 0 | hSpCas9 | negative selection | 181535 | 1731232 | 1731255 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Jiyoye | viability | GAGGTGAGGAAGCTGAGCACGGG | WDR81 | ENSG00000276021 | -2.6655809609294407 | [243] | [28] | -9 | hSpCas9 | negative selection | 181536 | 1732761 | 1732784 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Jiyoye | viability | GCAGCTCGTCCAGCAGGGCGGGG | WDR81 | ENSG00000276021 | 2.930737337562886 | [3] | [22] | 9 | hSpCas9 | negative selection | 181537 | 1735590 | 1735613 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Jiyoye | viability | CCAGCGGCTCCACTGTGCGAAGG | WDR81 | ENSG00000276021 | -1.8407521319377123 | [37] | [7] | -8 | hSpCas9 | negative selection | 181538 | 1735670 | 1735693 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Jiyoye | viability | GGTAGAGTCAGAGCTGGCCATGG | WDR81 | ENSG00000276021 | -2.4932889449432123 | [111] | [14] | -9 | hSpCas9 | negative selection | 181539 | 1730896 | 1730919 | CHR_HSCHR17_1_CTG2 | - | 26472758 | KBM7 | viability | GGACAGGCTCCCCATACAGGCGG | WDR81 | ENSG00000276021 | -0.48020366719075813 | [223,221] | [84,66] | -4 | hSpCas9 | negative selection | 372648 | 1736080 | 1736103 | CHR_HSCHR17_1_CTG2 | - | 26472758 | KBM7 | viability | GCCAGGGCACGGACAAGCCCAGG | WDR81 | ENSG00000276021 | 0.5223988243120716 | [358,232] | [129,255] | 5 | hSpCas9 | negative selection | 372649 | 1732785 | 1732808 | CHR_HSCHR17_1_CTG2 | + | 26472758 | KBM7 | viability | GAAGGTGTTCACCCTGGAGATGG | WDR81 | ENSG00000276021 | -0.4870854077417954 | [756,627] | [226,234] | -4 | hSpCas9 | negative selection | 372650 | 1730407 | 1730430 | CHR_HSCHR17_1_CTG2 | - | 26472758 | KBM7 | viability | CGAGCTTGGCAGACAGCCAGCGG | WDR81 | ENSG00000276021 | 0.3541736084409901 | [460,364] | [312,186] | 4 | hSpCas9 | negative selection | 372651 | 1730774 | 1730797 | CHR_HSCHR17_1_CTG2 | + | 26472758 | KBM7 | viability | CAGCAGTTCACAGTGAGCAGTGG | WDR81 | ENSG00000276021 | 0.9281043128756866 | [806,499] | [696,462] | 8 | hSpCas9 | negative selection | 372652 | 1730804 | 1730827 | CHR_HSCHR17_1_CTG2 | - | 26472758 | KBM7 | viability | ATGTTGCCGGCGCTCAGCGGTGG | WDR81 | ENSG00000276021 | 1.2168750136390951 | [148,97] | [202,69] | 9 | hSpCas9 | negative selection | 372653 | 1731232 | 1731255 | CHR_HSCHR17_1_CTG2 | - | 26472758 | KBM7 | viability | GAGGTGAGGAAGCTGAGCACGGG | WDR81 | ENSG00000276021 | -1.8581450814766083 | [557,559] | [65,78] | -8 | hSpCas9 | negative selection | 372654 | 1732761 | 1732784 | CHR_HSCHR17_1_CTG2 | - | 26472758 | KBM7 | viability | GCAGCTCGTCCAGCAGGGCGGGG | WDR81 | ENSG00000276021 | -0.7845417170765634 | [74,16] | [5,16] | -6 | hSpCas9 | negative selection | 372655 | 1735590 | 1735613 | CHR_HSCHR17_1_CTG2 | - | 26472758 | KBM7 | viability | CCAGCGGCTCCACTGTGCGAAGG | WDR81 | ENSG00000276021 | -0.040162679007666346 | [156,233] | [107,76] | 0 | hSpCas9 | negative selection | 372656 | 1735670 | 1735693 | CHR_HSCHR17_1_CTG2 | - | 26472758 | KBM7 | viability | GGTAGAGTCAGAGCTGGCCATGG | WDR81 | ENSG00000276021 | -0.08951986003946466 | [124,89] | [47,45] | -1 | hSpCas9 | negative selection | 372657 | 1730896 | 1730919 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Raji | viability | GGACAGGCTCCCCATACAGGCGG | WDR81 | ENSG00000276021 | 0.21121934635813955 | [133] | [35] | 2 | hSpCas9 | negative selection | 563766 | 1736080 | 1736103 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Raji | viability | GCCAGGGCACGGACAAGCCCAGG | WDR81 | ENSG00000276021 | -0.08816727374420741 | [141] | [30] | 0 | hSpCas9 | negative selection | 563767 | 1732785 | 1732808 | CHR_HSCHR17_1_CTG2 | + | 26472758 | Raji | viability | GAAGGTGTTCACCCTGGAGATGG | WDR81 | ENSG00000276021 | -0.7255064787911422 | [341] | [47] | -5 | hSpCas9 | negative selection | 563768 | 1730407 | 1730430 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Raji | viability | CGAGCTTGGCAGACAGCCAGCGG | WDR81 | ENSG00000276021 | 1.3558818480495127 | [132] | [78] | 9 | hSpCas9 | negative selection | 563769 | 1730774 | 1730797 | CHR_HSCHR17_1_CTG2 | + | 26472758 | Raji | viability | CAGCAGTTCACAGTGAGCAGTGG | WDR81 | ENSG00000276021 | -0.7743535830065807 | [397] | [53] | -5 | hSpCas9 | negative selection | 563770 | 1730804 | 1730827 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Raji | viability | ATGTTGCCGGCGCTCAGCGGTGG | WDR81 | ENSG00000276021 | 0.5224210346524432 | [89] | [29] | 5 | hSpCas9 | negative selection | 563771 | 1731232 | 1731255 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Raji | viability | GAGGTGAGGAAGCTGAGCACGGG | WDR81 | ENSG00000276021 | -2.8297896271709613 | [336] | [10] | -9 | hSpCas9 | negative selection | 563772 | 1732761 | 1732784 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Raji | viability | GCAGCTCGTCCAGCAGGGCGGGG | WDR81 | ENSG00000276021 | 1.048489846320031 | [24] | [11] | 8 | hSpCas9 | negative selection | 563773 | 1735590 | 1735613 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Raji | viability | CCAGCGGCTCCACTGTGCGAAGG | WDR81 | ENSG00000276021 | 0.24344508494962813 | [90] | [24] | 2 | hSpCas9 | negative selection | 563774 | 1735670 | 1735693 | CHR_HSCHR17_1_CTG2 | - | 26472758 | Raji | viability | GGTAGAGTCAGAGCTGGCCATGG | WDR81 | ENSG00000276021 | 0.5964216160962201 | [56] | [19] | 5 | hSpCas9 | negative selection | 563775 | 1730896 | 1730919 | CHR_HSCHR17_1_CTG2 | - | 26472758 | K562 | viability | GGACAGGCTCCCCATACAGGCGG | WDR81 | ENSG00000276021 | -1.1952044098906698 | [216] | [79] | -6 | hSpCas9 | negative selection | 754884 | 1736080 | 1736103 | CHR_HSCHR17_1_CTG2 | - | 26472758 | K562 | viability | GCCAGGGCACGGACAAGCCCAGG | WDR81 | ENSG00000276021 | -0.17273882348676628 | [226] | [169] | -1 | hSpCas9 | negative selection | 754885 | 1732785 | 1732808 | CHR_HSCHR17_1_CTG2 | + | 26472758 | K562 | viability | GAAGGTGTTCACCCTGGAGATGG | WDR81 | ENSG00000276021 | -0.7501199596633873 | [790] | [396] | -4 | hSpCas9 | negative selection | 754886 | 1730407 | 1730430 | CHR_HSCHR17_1_CTG2 | - | 26472758 | K562 | viability | CGAGCTTGGCAGACAGCCAGCGG | WDR81 | ENSG00000276021 | -0.1865332609757706 | [394] | [292] | -1 | hSpCas9 | negative selection | 754887 | 1730774 | 1730797 | CHR_HSCHR17_1_CTG2 | + | 26472758 | K562 | viability | CAGCAGTTCACAGTGAGCAGTGG | WDR81 | ENSG00000276021 | 1.0206898587671849 | [629] | [1078] | 8 | hSpCas9 | negative selection | 754888 | 1730804 | 1730827 | CHR_HSCHR17_1_CTG2 | - | 26472758 | K562 | viability | ATGTTGCCGGCGCTCAGCGGTGG | WDR81 | ENSG00000276021 | -0.29990178855736316 | [69] | [47] | -2 | hSpCas9 | negative selection | 754889 | 1731232 | 1731255 | CHR_HSCHR17_1_CTG2 | - | 26472758 | K562 | viability | GAGGTGAGGAAGCTGAGCACGGG | WDR81 | ENSG00000276021 | -2.5406833875440293 | [385] | [55] | -8 | hSpCas9 | negative selection | 754890 | 1732761 | 1732784 | CHR_HSCHR17_1_CTG2 | - | 26472758 | K562 | viability | GCAGCTCGTCCAGCAGGGCGGGG | WDR81 | ENSG00000276021 | -0.6223147414700896 | [30] | [16] | -4 | hSpCas9 | negative selection | 754891 | 1735590 | 1735613 | CHR_HSCHR17_1_CTG2 | - | 26472758 | K562 | viability | CCAGCGGCTCCACTGTGCGAAGG | WDR81 | ENSG00000276021 | 0.24441872766644712 | [96] | [96] | 1 | hSpCas9 | negative selection | 754892 | 1735670 | 1735693 | CHR_HSCHR17_1_CTG2 | - | 26472758 | K562 | viability | GGTAGAGTCAGAGCTGGCCATGG | WDR81 | ENSG00000276021 | -0.0876573225969981 | [106] | [84] | 0 | hSpCas9 | negative selection | 754893 | 1716606 | 1716629 | 17 | - | 26627737 | DLD1 | viability | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | -0.8495181790033288 | [1422] | [266,349,143] | -7 | hSpCas9 | negative selection | 796261 | 1725115 | 1725138 | 17 | - | 26627737 | DLD1 | viability | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | 0.3445477356942701 | [745] | [349,397,164] | 3 | hSpCas9 | negative selection | 796270 | 1716606 | 1716629 | 17 | - | 26627737 | GBM cells | viability after 5 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.09285575744653385 | [555] | [286,348] | 1 | hSpCas9 | negative selection | 878576 | 1725115 | 1725138 | 17 | - | 26627737 | GBM cells | viability after 5 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | -0.39707095274939486 | [495] | [173,229] | -6 | hSpCas9 | negative selection | 878585 | 1716606 | 1716629 | 17 | - | 26627737 | GBM cells | viability after 13 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.16193717371525707 | [555] | [390,293] | 2 | hSpCas9 | negative selection | 960891 | 1725115 | 1725138 | 17 | - | 26627737 | GBM cells | viability after 13 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | -0.38137620463854605 | [495] | [242,176] | -4 | hSpCas9 | negative selection | 960900 | 1716606 | 1716629 | 17 | - | 26627737 | GBM cells | viability after 21 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.6246181395485584 | [555] | [483,448] | 6 | hSpCas9 | negative selection | 1043206 | 1725115 | 1725138 | 17 | - | 26627737 | GBM cells | viability after 21 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | -0.6794526796668343 | [495] | [173,162] | -5 | hSpCas9 | negative selection | 1043215 | 1716606 | 1716629 | 17 | - | 26627737 | RPE1 | viability after 9 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | -0.8936323184351935 | [2915] | [369,647] | -6 | hSpCas9 | negative selection | 1125521 | 1725115 | 1725138 | 17 | - | 26627737 | RPE1 | viability after 9 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | -0.2025600932509969 | [1732] | [398,564] | -1 | hSpCas9 | negative selection | 1125530 | 1716606 | 1716629 | 17 | - | 26627737 | RPE1 | viability after 12 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | -1.1429175756473189 | [2915] | [278,434] | -7 | hSpCas9 | negative selection | 1207836 | 1725115 | 1725138 | 17 | - | 26627737 | RPE1 | viability after 12 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | -0.3057270172487798 | [1732] | [450,297] | -2 | hSpCas9 | negative selection | 1207845 | 1716606 | 1716629 | 17 | - | 26627737 | RPE1 | viability after 15 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | -1.3134586822227603 | [2915] | [337,325] | -7 | hSpCas9 | negative selection | 1290151 | 1725115 | 1725138 | 17 | - | 26627737 | RPE1 | viability after 15 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | -1.0308517374582549 | [1732] | [243,235] | -6 | hSpCas9 | negative selection | 1290160 | 1716606 | 1716629 | 17 | - | 26627737 | RPE1 | viability after 18 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | -1.2368324133078827 | [2915] | [228,445] | -6 | hSpCas9 | negative selection | 1372466 | 1725115 | 1725138 | 17 | - | 26627737 | RPE1 | viability after 18 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | -1.0192675133283033 | [1732] | [193,269] | -6 | hSpCas9 | negative selection | 1372475 | 1716606 | 1716629 | 17 | - | 26627737 | HeLa | viability after 8 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.6177014632084521 | [962] | [575,810,534] | 5 | hSpCas9 | negative selection | 1454781 | 1725115 | 1725138 | 17 | - | 26627737 | HeLa | viability after 8 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | -0.6489628211054518 | [649] | [208,210,130] | -6 | hSpCas9 | negative selection | 1454790 | 1716606 | 1716629 | 17 | - | 26627737 | HeLa | viability after 12 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.4006691116434662 | [962] | [285,592,682] | 3 | hSpCas9 | negative selection | 1537096 | 1725115 | 1725138 | 17 | - | 26627737 | HeLa | viability after 12 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | 0.06870709598452218 | [649] | [198,288,353] | 0 | hSpCas9 | negative selection | 1537105 | 1716606 | 1716629 | 17 | - | 26627737 | HeLa | viability after 15 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.5438003210789133 | [962] | [324,648,757] | 4 | hSpCas9 | negative selection | 1619411 | 1725115 | 1725138 | 17 | - | 26627737 | HeLa | viability after 15 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | 0.6674761403499372 | [649] | [354,494,410] | 5 | hSpCas9 | negative selection | 1619420 | 1716606 | 1716629 | 17 | - | 26627737 | HeLa | viability after 18 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.5430534772742626 | [962] | [216,537,757] | 4 | hSpCas9 | negative selection | 1701726 | 1725115 | 1725138 | 17 | - | 26627737 | HeLa | viability after 18 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | 0.6644878038358399 | [649] | [237,407,410] | 5 | hSpCas9 | negative selection | 1701735 | 1716606 | 1716629 | 17 | - | 26627737 | HCT116 | viability after 6 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.47819377944453434 | [1503] | [572,194] | 2 | hSpCas9 | negative selection | 1784041 | 1725115 | 1725138 | 17 | - | 26627737 | HCT116 | viability after 6 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | 0.9426662745999826 | [1080] | [490,235] | 5 | hSpCas9 | negative selection | 1784050 | 1716606 | 1716629 | 17 | - | 26627737 | HCT116 | viability after 8 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.26120852850475473 | [693] | [338,425,605] | 3 | hSpCas9 | negative selection | 1866356 | 1725115 | 1725138 | 17 | - | 26627737 | HCT116 | viability after 8 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | -0.5843737556846964 | [668] | [208,288,238] | -6 | hSpCas9 | negative selection | 1866365 | 1716606 | 1716629 | 17 | - | 26627737 | HCT116 | viability after 9 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.726888153352871 | [1503] | [953,435] | 5 | hSpCas9 | negative selection | 1948671 | 1725115 | 1725138 | 17 | - | 26627737 | HCT116 | viability after 9 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | 0.2517807569985596 | [1080] | [360,329] | 2 | hSpCas9 | negative selection | 1948680 | 1716606 | 1716629 | 17 | - | 26627737 | HCT116 | viability after 12 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.07786531872289348 | [693] | [313,423,423] | 0 | hSpCas9 | negative selection | 2030986 | 1725115 | 1725138 | 17 | - | 26627737 | HCT116 | viability after 12 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | -0.9549703244068566 | [668] | [121,168,257] | -8 | hSpCas9 | negative selection | 2030995 | 1716606 | 1716629 | 17 | - | 26627737 | HCT116 | viability after 15 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.36614724508352303 | [693] | [635,571,349] | 3 | hSpCas9 | negative selection | 2113301 | 1725115 | 1725138 | 17 | - | 26627737 | HCT116 | viability after 15 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | -0.579632932807939 | [668] | [245,274,248] | -5 | hSpCas9 | negative selection | 2113310 | 1716606 | 1716629 | 17 | - | 26627737 | HCT116 | viability after 18 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | -0.009910906813247244 | [693] | [436,261,303] | 0 | hSpCas9 | negative selection | 2195616 | 1725115 | 1725138 | 17 | - | 26627737 | HCT116 | viability after 18 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | -0.9891338548566754 | [668] | [125,107,262] | -7 | hSpCas9 | negative selection | 2195625 | 1724649 | 1724672 | 17 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | ACAAGCGCACGTGGCTCCAGAGG | WDR81 | ENSG00000167716 | -0.06954549539492727 | [40,59] | [11,7] | 0 | dCas9-VP64 | positive selection | 2404117 | 1724657 | 1724680 | CHR_HSCHR17_1_CTG2 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | ACAAGCGCACGTGGCTCCAGAGG | WDR81 | ENSG00000276021 | -0.06954549539492727 | [40,59] | [11,7] | 0 | dCas9-VP64 | positive selection | 2404118 | 1724682 | 1724705 | CHR_HSCHR17_1_CTG2 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GTCACGTGATCGCCCCAGCACGG | WDR81 | ENSG00000276021 | 1.1845290767288084 | [112,21] | [58,4] | 4 | dCas9-VP64 | positive selection | 2404119 | 1724674 | 1724697 | 17 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GTCACGTGATCGCCCCAGCACGG | WDR81 | ENSG00000167716 | 1.1845290767288084 | [112,21] | [58,4] | 4 | dCas9-VP64 | positive selection | 2404120 | 1724715 | 1724738 | CHR_HSCHR17_1_CTG2 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGACCCGTCACGGTGGAGCCCGG | WDR81 | ENSG00000276021 | 1.019641592305189 | [30,103] | [3,57] | 4 | dCas9-VP64 | positive selection | 2404121 | 1724707 | 1724730 | 17 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGACCCGTCACGGTGGAGCCCGG | WDR81 | ENSG00000167716 | 1.019641592305189 | [30,103] | [3,57] | 4 | dCas9-VP64 | positive selection | 2404122 | 1724441 | 1724464 | CHR_HSCHR17_1_CTG2 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CATCTCTGGGAACAGCCTCCGGG | WDR81 | ENSG00000276021 | -0.0623115158077443 | [235,742] | [23,189] | 0 | dCas9-VP64 | positive selection | 2404123 | 1724433 | 1724456 | 17 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CATCTCTGGGAACAGCCTCCGGG | WDR81 | ENSG00000167716 | -0.0623115158077443 | [235,742] | [23,189] | 0 | dCas9-VP64 | positive selection | 2404124 | 1724418 | 1724441 | CHR_HSCHR17_1_CTG2 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TCCGCACTTAACTAAGAGGCTGG | WDR81 | ENSG00000276021 | -0.5824830953298126 | [14,35] | [4,1] | -3 | dCas9-VP64 | positive selection | 2404125 | 1724410 | 1724433 | 17 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TCCGCACTTAACTAAGAGGCTGG | WDR81 | ENSG00000167716 | -0.5824830953298126 | [14,35] | [4,1] | -3 | dCas9-VP64 | positive selection | 2404126 | 1724365 | 1724388 | CHR_HSCHR17_1_CTG2 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGTTGTGTCTATTTTTGAGACGG | WDR81 | ENSG00000276021 | 0.4997421337367496 | [524,509] | [171,147] | 2 | dCas9-VP64 | positive selection | 2404127 | 1724357 | 1724380 | 17 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGTTGTGTCTATTTTTGAGACGG | WDR81 | ENSG00000167716 | 0.4997421337367496 | [524,509] | [171,147] | 2 | dCas9-VP64 | positive selection | 2404128 | 1734745 | 1734768 | CHR_HSCHR17_1_CTG2 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CGCACCACTGCACTCCAGCCCGG | WDR81 | ENSG00000276021 | 3.0347564003538725 | [8,6] | [27,0] | 8 | dCas9-VP64 | positive selection | 2470797 | 1724649 | 1724672 | 17 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | ACAAGCGCACGTGGCTCCAGAGG | WDR81 | ENSG00000167716 | 1.203505732579671 | [200,193] | [269,35] | 7 | dCas9-VP64 | positive selection | 2499372 | 1724657 | 1724680 | CHR_HSCHR17_1_CTG2 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | ACAAGCGCACGTGGCTCCAGAGG | WDR81 | ENSG00000276021 | 1.203505732579671 | [200,193] | [269,35] | 7 | dCas9-VP64 | positive selection | 2499373 | 1724682 | 1724705 | CHR_HSCHR17_1_CTG2 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GTCACGTGATCGCCCCAGCACGG | WDR81 | ENSG00000276021 | 1.1159609425326218 | [65,204] | [157,35] | 7 | dCas9-VP64 | positive selection | 2499374 | 1724674 | 1724697 | 17 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GTCACGTGATCGCCCCAGCACGG | WDR81 | ENSG00000167716 | 1.1159609425326218 | [65,204] | [157,35] | 7 | dCas9-VP64 | positive selection | 2499375 | 1724715 | 1724738 | CHR_HSCHR17_1_CTG2 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGACCCGTCACGGTGGAGCCCGG | WDR81 | ENSG00000276021 | -0.34376260727468627 | [204,106] | [52,27] | -3 | dCas9-VP64 | positive selection | 2499376 | 1724707 | 1724730 | 17 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGACCCGTCACGGTGGAGCCCGG | WDR81 | ENSG00000167716 | -0.34376260727468627 | [204,106] | [52,27] | -3 | dCas9-VP64 | positive selection | 2499377 | 1724441 | 1724464 | CHR_HSCHR17_1_CTG2 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CATCTCTGGGAACAGCCTCCGGG | WDR81 | ENSG00000276021 | 0.30409445450160183 | [167,109] | [49,61] | 2 | dCas9-VP64 | positive selection | 2499378 | 1724433 | 1724456 | 17 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CATCTCTGGGAACAGCCTCCGGG | WDR81 | ENSG00000167716 | 0.30409445450160183 | [167,109] | [49,61] | 2 | dCas9-VP64 | positive selection | 2499379 | 1724418 | 1724441 | CHR_HSCHR17_1_CTG2 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TCCGCACTTAACTAAGAGGCTGG | WDR81 | ENSG00000276021 | -0.13775795773290667 | [85,45] | [26,11] | -1 | dCas9-VP64 | positive selection | 2499380 | 1724410 | 1724433 | 17 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TCCGCACTTAACTAAGAGGCTGG | WDR81 | ENSG00000167716 | -0.13775795773290667 | [85,45] | [26,11] | -1 | dCas9-VP64 | positive selection | 2499381 | 1724365 | 1724388 | CHR_HSCHR17_1_CTG2 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGTTGTGTCTATTTTTGAGACGG | WDR81 | ENSG00000276021 | -1.0482411419674207 | [265,265] | [48,34] | -8 | dCas9-VP64 | positive selection | 2499382 | 1724357 | 1724380 | 17 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGTTGTGTCTATTTTTGAGACGG | WDR81 | ENSG00000167716 | -1.0482411419674207 | [265,265] | [48,34] | -8 | dCas9-VP64 | positive selection | 2499383 | 1734745 | 1734768 | CHR_HSCHR17_1_CTG2 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CGCACCACTGCACTCCAGCCCGG | WDR81 | ENSG00000276021 | 0.038175304513698105 | [60,77] | [26,18] | 0 | dCas9-VP64 | positive selection | 2566052 | 1716560 | 1716583 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | TCTGCGTTTGCAATGCATGCTGG | WDR81 | ENSG00000276021 | 0.21183898025674452 | [372,400] | [127,284] | 1 | hSpCas9 | positive selection | 2963971 | 1716560 | 1716583 | 17 | + | 27013184 | SW480 | treatment with recombinant TRAIL | TCTGCGTTTGCAATGCATGCTGG | WDR81 | ENSG00000167716 | 0.21183898025674452 | [372,400] | [127,284] | 1 | hSpCas9 | positive selection | 2963972 | 1716620 | 1716643 | 17 | + | 27013184 | SW480 | treatment with recombinant TRAIL | ACCCAGCGCGCTCTGTGAGTTGG | WDR81 | ENSG00000167716 | -0.8236182427356564 | [407,566] | [105,132] | -4 | hSpCas9 | positive selection | 2963973 | 1716620 | 1716643 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | ACCCAGCGCGCTCTGTGAGTTGG | WDR81 | ENSG00000276021 | -0.8236182427356564 | [407,566] | [105,132] | -4 | hSpCas9 | positive selection | 2963974 | 1730449 | 1730472 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | GGAGCAGGTTCCGGGCCACGTGG | WDR81 | ENSG00000276021 | 0.2549432739061739 | [71,79] | [33,45] | 1 | hSpCas9 | positive selection | 2963976 | 1730458 | 1730481 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | TCAGCAGGCGGAGCAGGTTCCGG | WDR81 | ENSG00000276021 | 0.755976931307292 | [150,97] | [77,112] | 3 | hSpCas9 | positive selection | 2963978 | 1730749 | 1730772 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | GAGTGGGTCCTGCCACGGAAGGG | WDR81 | ENSG00000276021 | 0.011553755726622764 | [148,277] | [51,144] | 0 | hSpCas9 | positive selection | 2963980 | 1730750 | 1730773 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | CGAGTGGGTCCTGCCACGGAAGG | WDR81 | ENSG00000276021 | -2.719211660814584 | [169,218] | [5,21] | -8 | hSpCas9 | positive selection | 2963982 | 1730765 | 1730788 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | ACTGTGAACTGCTGCCGAGTGGG | WDR81 | ENSG00000276021 | 2.0435668736469217 | [119,127] | [233,199] | 8 | hSpCas9 | positive selection | 2963983 | 1730766 | 1730789 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | CACTGTGAACTGCTGCCGAGTGG | WDR81 | ENSG00000276021 | -0.08449540462842964 | [410,614] | [214,190] | 0 | hSpCas9 | positive selection | 2963985 | 1730807 | 1730830 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | TAGATGTTGCCGGCGCTCAGCGG | WDR81 | ENSG00000276021 | -2.7432454429129747 | [243,594] | [11,45] | -8 | hSpCas9 | positive selection | 2963988 | 1730845 | 1730868 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | GCCCTGACACGATGTCGCCCAGG | WDR81 | ENSG00000276021 | -0.11451263606796602 | [506,611] | [254,172] | 0 | hSpCas9 | positive selection | 2963989 | 1730884 | 1730907 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | CATACAGGCGGGCGATGTGGAGG | WDR81 | ENSG00000276021 | -0.5413567639690819 | [188,226] | [9,133] | -2 | hSpCas9 | positive selection | 2963991 | 1730887 | 1730910 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | CCCCATACAGGCGGGCGATGTGG | WDR81 | ENSG00000276021 | -0.23845061966249204 | [55,50] | [17,21] | -1 | hSpCas9 | positive selection | 2963994 | 1730899 | 1730922 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | TGAGGACAGGCTCCCCATACAGG | WDR81 | ENSG00000276021 | -0.1263248174647762 | [426,658] | [151,293] | 0 | hSpCas9 | positive selection | 2963996 | 1730926 | 1730949 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | AGCTGATGTAGGGCAGGTACTGG | WDR81 | ENSG00000276021 | 0.7267941049950285 | [258,224] | [137,224] | 3 | hSpCas9 | positive selection | 2963997 | 1730932 | 1730955 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | CCAGGTAGCTGATGTAGGGCAGG | WDR81 | ENSG00000276021 | 0.6081809218948981 | [219,194] | [142,128] | 3 | hSpCas9 | positive selection | 2963999 | 1730936 | 1730959 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | CTGACCAGGTAGCTGATGTAGGG | WDR81 | ENSG00000276021 | -3.4364857489868115 | [183,148] | [9,1] | -9 | hSpCas9 | positive selection | 2964002 | 1730937 | 1730960 | CHR_HSCHR17_1_CTG2 | - | 27013184 | SW480 | treatment with recombinant TRAIL | ACTGACCAGGTAGCTGATGTAGG | WDR81 | ENSG00000276021 | -0.05709530759178305 | [376,212] | [138,105] | 0 | hSpCas9 | positive selection | 2964003 | 1730489 | 1730512 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | TATGTTGGTAAGGAGGCCTGCGG | WDR81 | ENSG00000276021 | 1.393877768078388 | [194,285] | [100,505] | 6 | hSpCas9 | positive selection | 2964005 | 1730751 | 1730774 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | CTTCCGTGGCAGGACCCACTCGG | WDR81 | ENSG00000276021 | 1.6516101751812742 | [294,702] | [762,493] | 7 | hSpCas9 | positive selection | 2964008 | 1730774 | 1730797 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | CAGCAGTTCACAGTGAGCAGTGG | WDR81 | ENSG00000276021 | 0.6228673683737554 | [210,230] | [52,278] | 3 | hSpCas9 | positive selection | 2964010 | 1730827 | 1730850 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | CTACCAGAAGAGGCCGGTCCTGG | WDR81 | ENSG00000276021 | 0.2468835838369867 | [308,177] | [66,213] | 1 | hSpCas9 | positive selection | 2964011 | 1730828 | 1730851 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | TACCAGAAGAGGCCGGTCCTGGG | WDR81 | ENSG00000276021 | -0.6776267137676732 | [264,444] | [79,112] | -3 | hSpCas9 | positive selection | 2964014 | 1730843 | 1730866 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | GTCCTGGGCGACATCGTGTCAGG | WDR81 | ENSG00000276021 | 1.323576542884227 | [131,389] | [193,376] | 6 | hSpCas9 | positive selection | 2964015 | 1730844 | 1730867 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | TCCTGGGCGACATCGTGTCAGGG | WDR81 | ENSG00000276021 | -0.29721509156852766 | [170,91] | [46,47] | -1 | hSpCas9 | positive selection | 2964017 | 1730885 | 1730908 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | CTCCACATCGCCCGCCTGTATGG | WDR81 | ENSG00000276021 | 0.13692986657553075 | [310,509] | [216,152] | 0 | hSpCas9 | positive selection | 2964019 | 1730886 | 1730909 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | TCCACATCGCCCGCCTGTATGGG | WDR81 | ENSG00000276021 | 0.6368128254955268 | [443,888] | [246,699] | 3 | hSpCas9 | positive selection | 2964021 | 1730887 | 1730910 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | CCACATCGCCCGCCTGTATGGGG | WDR81 | ENSG00000276021 | 1.0974045799914727 | [238,167] | [170,218] | 5 | hSpCas9 | positive selection | 2964024 | 1730932 | 1730955 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | CCTGCCCTACATCAGCTACCTGG | WDR81 | ENSG00000276021 | 2.38222585527649 | [635,485] | [695,2103] | 8 | hSpCas9 | positive selection | 2964025 | 1730943 | 1730966 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | TCAGCTACCTGGTCAGTCGCTGG | WDR81 | ENSG00000276021 | 0.6688225880384527 | [79,149] | [51,111] | 3 | hSpCas9 | positive selection | 2964028 | 1728529 | 1728552 | CHR_HSCHR17_1_CTG2 | + | 27013184 | SW480 | treatment with recombinant TRAIL | TCCATGGAGACGGTTGTGGCCGG | WDR81 | ENSG00000276021 | -0.6580034992116424 | [160,73] | [26,41] | -3 | hSpCas9 | positive selection | 2964030 | 1716599 | 1716622 | | - | 24336571 | A375 | resistance to PLX after 7 days | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.3647236308341287 | [7,11] | [6,7] | -8 | hSpCas9 | positive selection | 3155578 | 1716622 | 1716645 | | - | 24336571 | A375 | resistance to PLX after 7 days | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | 0.24523062189610823 | [6,4] | [6,5] | 7 | hSpCas9 | positive selection | 3155579 | 1716599 | 1716622 | | - | 24336571 | A375 | resistance to PLX after 14 days | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.14289204304910663 | [10,9] | [3,3] | -1 | hSpCas9 | positive selection | 3213371 | 1716622 | 1716645 | | - | 24336571 | A375 | resistance to PLX after 14 days | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | 0.38007966984268804 | [4,3] | [2,1] | 3 | hSpCas9 | positive selection | 3213372 | 1716599 | 1716622 | | - | 24336571 | A375 | viability after 7 days | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.6072586246837215 | [6] | [7,11] | 8 | hSpCas9 | negative selection | 3271164 | 1716622 | 1716645 | | - | 24336571 | A375 | viability after 7 days | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.3429072305527404 | [7] | [6,4] | -5 | hSpCas9 | negative selection | 3271165 | 1716599 | 1716622 | | - | 24336571 | A375 | viability after 14 days | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.6662423102746717 | [6] | [10,9] | 8 | hSpCas9 | negative selection | 3328957 | 1716622 | 1716645 | | - | 24336571 | A375 | viability after 14 days | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.57201407069222 | [7] | [4,3] | -6 | hSpCas9 | negative selection | 3328958 | 1716599 | 1716622 | 17 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.46291034509572904 | [110,110] | [0,0] | 2 | hSpCas9 | positive selection | 3401380 | 1716622 | 1716645 | 17 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | 0.48914188666890873 | [108,108] | [0,0] | 2 | hSpCas9 | positive selection | 3401381 | 1725150 | 1725173 | 17 | - | 26780180 | A375 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 1.57099130255678 | [] | [] | 8 | hSpCas9 | negative selection | 4012539 | 1716599 | 1716622 | 17 | - | 26780180 | A375 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.914896266616835 | [] | [] | 4 | hSpCas9 | negative selection | 4012540 | 1716622 | 1716645 | 17 | - | 26780180 | A375 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | 2.13871454824699 | [] | [] | 9 | hSpCas9 | negative selection | 4012541 | 1725150 | 1725173 | 17 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.705045679867014 | [] | [] | 2 | hSpCas9 | negative selection | 4120505 | 1716599 | 1716622 | 17 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.850949851228932 | [] | [] | 3 | hSpCas9 | negative selection | 4120506 | 1716622 | 1716645 | 17 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | 2.10901858764703 | [] | [] | 9 | hSpCas9 | negative selection | 4120507 | 1716599 | 1716622 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.21690853552549416 | [3] | [1,1] | -5 | hSpCas9 | positive selection | 4182384 | 1716622 | 1716645 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | 1.474019592319157 | [1] | [8,1] | 9 | hSpCas9 | positive selection | 4182385 | 1716599 | 1716622 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.5347950922667316 | [2] | [4,1,0,0] | 3 | hSpCas9 | positive selection | 4246406 | 1716622 | 1716645 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.33252893711972786 | [3] | [2,0,1,0] | -5 | hSpCas9 | positive selection | 4246407 | 1725150 | 1725173 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.29877871461025746 | [2] | [2,2] | 6 | hSpCas9 | positive selection | 4307805 | 1716599 | 1716622 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.08287450716746793 | [2] | [2,1] | -2 | hSpCas9 | positive selection | 4372052 | 1716622 | 1716645 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.4867703238597997 | [3] | [2,0] | -8 | hSpCas9 | positive selection | 4372053 | 1716814 | 1716837 | 17 | + | 27661255 | K562 | viability | GGGCAGAGCGTCAGCCCCCAGGG | WDR81 | ENSG00000167716 | 0.18889416304332088 | [592,679] | [670,498] | 6 | dCas9-KRAB | negative selection | 5522753 | 1725066 | 1725089 | 17 | + | 27661255 | K562 | viability | GGGACCTGAGCATCGATCCCAGG | WDR81 | ENSG00000167716 | 0.08724305967642798 | [1276,1270] | [1179,996] | 3 | dCas9-KRAB | negative selection | 5522754 | 1716599 | 1716622 | 17 | - | 27661255 | K562 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.126935238343441 | [160,80] | [95,115] | 4 | dCas9-KRAB | negative selection | 5522755 | 1716606 | 1716629 | 17 | - | 27661255 | K562 | viability | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.1393021314577716 | [245,344] | [279,239] | 5 | dCas9-KRAB | negative selection | 5522756 | 1724777 | 1724800 | 17 | - | 27661255 | K562 | viability | GGGGCGCGCTTACCCCTCCGCGG | WDR81 | ENSG00000167716 | 0.5047563730977552 | [234,428] | [448,306] | 9 | dCas9-KRAB | negative selection | 5522757 | 1724796 | 1724819 | 17 | - | 27661255 | K562 | viability | GCGGCGAAGAGGCGGACGGGGGG | WDR81 | ENSG00000167716 | -0.2516149765443597 | [441,478] | [368,256] | -6 | dCas9-KRAB | negative selection | 5522758 | 1724799 | 1724822 | 17 | - | 27661255 | K562 | viability | GCGGCGGCGAAGAGGCGGACGGG | WDR81 | ENSG00000167716 | 0.07874415000408516 | [667,843] | [741,543] | 2 | dCas9-KRAB | negative selection | 5522759 | 1725154 | 1725177 | 17 | - | 27661255 | K562 | viability | GGGGCAGCCGGCGATCGCGGAGG | WDR81 | ENSG00000167716 | -0.10687640605542031 | [843,752] | [660,535] | -4 | dCas9-KRAB | negative selection | 5522760 | 1725173 | 1725196 | 17 | - | 27661255 | K562 | viability | GCGCGGGGACAGGGTCCCAGGGG | WDR81 | ENSG00000167716 | -0.20157259017187568 | [229,380] | [205,213] | -6 | dCas9-KRAB | negative selection | 5522761 | 1725150 | 1725173 | 17 | - | 27260156 | BXPC3 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.255531292287792 | [281] | [301,288,406,426] | 5 | hSpCas9 | negative selection | 5580265 | 1716599 | 1716622 | 17 | - | 27260156 | BXPC3 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.06627111270774716 | [416] | [322,319,552,494] | -1 | hSpCas9 | negative selection | 5644512 | 1716622 | 1716645 | 17 | - | 27260156 | BXPC3 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.4097996379204857 | [560] | [426,493,369,472] | -7 | hSpCas9 | negative selection | 5644513 | 1725150 | 1725173 | 17 | - | 27260156 | A673 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.20277946603027086 | [281] | [392,326,398,443] | 5 | hSpCas9 | negative selection | 5701516 | 1716599 | 1716622 | 17 | - | 27260156 | A673 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.14112061824750338 | [416] | [474,414,452,476] | -4 | hSpCas9 | negative selection | 5765763 | 1716622 | 1716645 | 17 | - | 27260156 | A673 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.5380530463208821 | [560] | [528,466,456,405] | -8 | hSpCas9 | negative selection | 5765764 | 1725150 | 1725173 | 17 | - | 27260156 | A375 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | -0.035011691941779 | [281] | [439,340,312,207] | 0 | hSpCas9 | negative selection | 5822767 | 1716599 | 1716622 | 17 | - | 27260156 | A375 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.10922496163647882 | [416] | [337,657,409,428] | -1 | hSpCas9 | negative selection | 5887014 | 1716622 | 1716645 | 17 | - | 27260156 | A375 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.13565101831956816 | [560] | [660,706,690,367] | -2 | hSpCas9 | negative selection | 5887015 | 1725150 | 1725173 | 17 | - | 27260156 | COLO741 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.22547245789048587 | [281] | [472,398,396] | 5 | hSpCas9 | negative selection | 5944018 | 1716599 | 1716622 | 17 | - | 27260156 | COLO741 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.1550677205299783 | [416] | [399,577,451] | -3 | hSpCas9 | negative selection | 6008265 | 1716622 | 1716645 | 17 | - | 27260156 | COLO741 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.452142246307535 | [560] | [558,454,556] | -7 | hSpCas9 | negative selection | 6008266 | 1725150 | 1725173 | 17 | - | 27260156 | CAL120 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.129795434887911 | [281] | [355,435,355] | 2 | hSpCas9 | negative selection | 6065269 | 1716599 | 1716622 | 17 | - | 27260156 | CAL120 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.8914073773662101 | [416] | [270,410,157] | -8 | hSpCas9 | negative selection | 6129516 | 1716622 | 1716645 | 17 | - | 27260156 | CAL120 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.6432275964953951 | [560] | [250,262,790] | -7 | hSpCas9 | negative selection | 6129517 | 1725150 | 1725173 | 17 | - | 27260156 | CADOES1 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.1330774540861045 | [281] | [249,220,274,408] | 2 | hSpCas9 | negative selection | 6186520 | 1716599 | 1716622 | 17 | - | 27260156 | CADOES1 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.23116748477441038 | [416] | [596,296,629,289] | 4 | hSpCas9 | negative selection | 6250767 | 1716622 | 1716645 | 17 | - | 27260156 | CADOES1 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.6089989424566419 | [560] | [315,331,286,436] | -8 | hSpCas9 | negative selection | 6250768 | 1725150 | 1725173 | 17 | - | 27260156 | EWS502 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.5955368240694354 | [281] | [359,416,572,468] | 8 | hSpCas9 | negative selection | 6307771 | 1716599 | 1716622 | 17 | - | 27260156 | EWS502 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.23998648781891446 | [416] | [381,288,502,320] | -4 | hSpCas9 | negative selection | 6372018 | 1716622 | 1716645 | 17 | - | 27260156 | EWS502 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.764294606785252 | [560] | [185,402,469,358] | -8 | hSpCas9 | negative selection | 6372019 | 1725150 | 1725173 | 17 | - | 27260156 | EW8 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.20278591333494178 | [281] | [222,306,263,252] | 4 | hSpCas9 | negative selection | 6429022 | 1716599 | 1716622 | 17 | - | 27260156 | EW8 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.08064936154980064 | [416] | [343,335,301,453] | 1 | hSpCas9 | negative selection | 6493269 | 1716622 | 1716645 | 17 | - | 27260156 | EW8 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.37400303718715855 | [560] | [438,305,433,218] | -6 | hSpCas9 | negative selection | 6493270 | 1725150 | 1725173 | 17 | - | 27260156 | CORL105 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.3217359258208201 | [281] | [531,372,471,287] | 6 | hSpCas9 | negative selection | 6550273 | 1716599 | 1716622 | 17 | - | 27260156 | CORL105 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.24352732301092023 | [416] | [324,455,435,431] | -4 | hSpCas9 | negative selection | 6614520 | 1716622 | 1716645 | 17 | - | 27260156 | CORL105 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.6272714333175295 | [560] | [336,465,477,423] | -8 | hSpCas9 | negative selection | 6614521 | 1725150 | 1725173 | 17 | - | 27260156 | HS294T | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.29240919182858877 | [281] | [162,110,111,147] | 4 | hSpCas9 | negative selection | 6671524 | 1716599 | 1716622 | 17 | - | 27260156 | HS294T | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.09560975014670742 | [416] | [114,138,111,258] | -1 | hSpCas9 | negative selection | 6735771 | 1716622 | 1716645 | 17 | - | 27260156 | HS294T | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.23852259966246575 | [560] | [248,100,213,163] | -3 | hSpCas9 | negative selection | 6735772 | 1725150 | 1725173 | 17 | - | 27260156 | HCC44 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.25785698225927095 | [281] | [352,422,493,266] | 4 | hSpCas9 | negative selection | 6792775 | 1716599 | 1716622 | 17 | - | 27260156 | HCC44 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.43429590648441596 | [416] | [353,239,406,415] | -6 | hSpCas9 | negative selection | 6857022 | 1716622 | 1716645 | 17 | - | 27260156 | HCC44 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.49899810301240055 | [560] | [541,446,304,480] | -6 | hSpCas9 | negative selection | 6857023 | 1725150 | 1725173 | 17 | - | 27260156 | G402 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.40521646712472303 | [281] | [514,253,236,794] | 5 | hSpCas9 | negative selection | 6914026 | 1716599 | 1716622 | 17 | - | 27260156 | G402 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.12731197616457363 | [416] | [790,177,439,481] | -2 | hSpCas9 | negative selection | 6978273 | 1716622 | 1716645 | 17 | - | 27260156 | G402 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | 0.674348296171585 | [560] | [676,2377,376,954] | 8 | hSpCas9 | negative selection | 6978274 | 1725150 | 1725173 | 17 | - | 27260156 | L33 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.41846019591804395 | [281] | [378,205,234,252] | 8 | hSpCas9 | negative selection | 7035277 | 1716599 | 1716622 | 17 | - | 27260156 | L33 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.3266993085181608 | [416] | [304,134,286,240] | -6 | hSpCas9 | negative selection | 7099524 | 1716622 | 1716645 | 17 | - | 27260156 | L33 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.6591259686683755 | [560] | [365,151,196,369] | -9 | hSpCas9 | negative selection | 7099525 | 1725150 | 1725173 | 17 | - | 27260156 | K562 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.03207248124106121 | [281] | [172,114,263,434] | 0 | hSpCas9 | negative selection | 7156528 | 1716599 | 1716622 | 17 | - | 27260156 | K562 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.394061553990948 | [416] | [463,309,784,384] | 5 | hSpCas9 | negative selection | 7220775 | 1716622 | 1716645 | 17 | - | 27260156 | K562 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.6756339373050632 | [560] | [559,194,375,147] | -7 | hSpCas9 | negative selection | 7220776 | 1725150 | 1725173 | 17 | - | 27260156 | HT29 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.45984865363009897 | [281] | [463,639,433,370] | 8 | hSpCas9 | negative selection | 7277779 | 1716599 | 1716622 | 17 | - | 27260156 | HT29 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.14754920381970316 | [416] | [584,434,428,393] | -3 | hSpCas9 | negative selection | 7342026 | 1716622 | 1716645 | 17 | - | 27260156 | HT29 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.6534045807734867 | [560] | [575,429,402,343] | -8 | hSpCas9 | negative selection | 7342027 | 1725150 | 1725173 | 17 | - | 27260156 | MHHES1 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.0505401897264659 | [281] | [320,285,346,344] | 0 | hSpCas9 | negative selection | 7399030 | 1716599 | 1716622 | 17 | - | 27260156 | MHHES1 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.2775528966622178 | [416] | [454,486,167,435] | -5 | hSpCas9 | negative selection | 7463277 | 1716622 | 1716645 | 17 | - | 27260156 | MHHES1 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | 0.15936010539255457 | [560] | [724,560,967,572] | 3 | hSpCas9 | negative selection | 7463278 | 1725150 | 1725173 | 17 | - | 27260156 | MEWO | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.3741712902542193 | [281] | [368,342,318] | 7 | hSpCas9 | negative selection | 7520281 | 1716599 | 1716622 | 17 | - | 27260156 | MEWO | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.31410046795522195 | [416] | [268,242,420] | -6 | hSpCas9 | negative selection | 7584528 | 1716622 | 1716645 | 17 | - | 27260156 | MEWO | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.3705276037842355 | [560] | [486,307,438] | -7 | hSpCas9 | negative selection | 7584529 | 1725150 | 1725173 | 17 | - | 27260156 | LNCAPCLONEFGC | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.23887554862527427 | [281] | [198,327,342,341] | 4 | hSpCas9 | negative selection | 7641532 | 1716599 | 1716622 | 17 | - | 27260156 | LNCAPCLONEFGC | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.008757160279665027 | [416] | [317,323,542,363] | 0 | hSpCas9 | negative selection | 7705779 | 1716622 | 1716645 | 17 | - | 27260156 | LNCAPCLONEFGC | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.665181475818671 | [560] | [296,385,348,249] | -7 | hSpCas9 | negative selection | 7705780 | 1725150 | 1725173 | 17 | - | 27260156 | PANC0327 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.3640169573342002 | [281] | [469,396,273,150] | 5 | hSpCas9 | negative selection | 7762783 | 1716599 | 1716622 | 17 | - | 27260156 | PANC0327 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.1824067888373394 | [416] | [268,464,405,522] | 2 | hSpCas9 | negative selection | 7827030 | 1716622 | 1716645 | 17 | - | 27260156 | PANC0327 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.21641174359110446 | [560] | [459,265,410,601] | -3 | hSpCas9 | negative selection | 7827031 | 1725150 | 1725173 | 17 | - | 27260156 | NCIH2009 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.7482078745003437 | [281] | [741,668,588] | 8 | hSpCas9 | negative selection | 7884034 | 1716599 | 1716622 | 17 | - | 27260156 | NCIH2009 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.07677182756226034 | [416] | [712,713,432] | 1 | hSpCas9 | negative selection | 7948281 | 1716622 | 1716645 | 17 | - | 27260156 | NCIH2009 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.3285927898236986 | [560] | [627,577,666] | -4 | hSpCas9 | negative selection | 7948282 | 1725150 | 1725173 | 17 | - | 27260156 | NCIH1373 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.6896969006140647 | [281] | [634,415,368,172] | 7 | hSpCas9 | negative selection | 8005285 | 1716599 | 1716622 | 17 | - | 27260156 | NCIH1373 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.36383962732575226 | [416] | [334,262,396,122] | -4 | hSpCas9 | negative selection | 8069532 | 1716622 | 1716645 | 17 | - | 27260156 | NCIH1373 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.7694641072652043 | [560] | [519,376,162,116] | -6 | hSpCas9 | negative selection | 8069533 | 1725150 | 1725173 | 17 | - | 27260156 | PATU8902 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.9883322072756466 | [281] | [823,707,637,1002] | 9 | hSpCas9 | negative selection | 8126536 | 1716599 | 1716622 | 17 | - | 27260156 | PATU8902 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.07745391522950631 | [416] | [548,717,559,636] | 0 | hSpCas9 | negative selection | 8190783 | 1716622 | 1716645 | 17 | - | 27260156 | PATU8902 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.3489738185693258 | [560] | [486,504,463,1089] | -3 | hSpCas9 | negative selection | 8190784 | 1725150 | 1725173 | 17 | - | 27260156 | PANC1 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.10571415792095795 | [281] | [271,352,235,204] | 1 | hSpCas9 | negative selection | 8247787 | 1716599 | 1716622 | 17 | - | 27260156 | PANC1 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.036255256971429034 | [416] | [382,438,302,353] | 0 | hSpCas9 | negative selection | 8312034 | 1716622 | 1716645 | 17 | - | 27260156 | PANC1 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.49996472748096044 | [560] | [407,328,309,310] | -6 | hSpCas9 | negative selection | 8312035 | 1725150 | 1725173 | 17 | - | 27260156 | PANC0813 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.7342044476026373 | [281] | [551,480,556,609] | 9 | hSpCas9 | negative selection | 8369038 | 1716599 | 1716622 | 17 | - | 27260156 | PANC0813 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.05354682540491559 | [416] | [599,479,408,412] | -1 | hSpCas9 | negative selection | 8433285 | 1716622 | 1716645 | 17 | - | 27260156 | PANC0813 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.5699342345366916 | [560] | [612,431,285,457] | -7 | hSpCas9 | negative selection | 8433286 | 1725150 | 1725173 | 17 | - | 27260156 | RDES | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.4278359783021632 | [281] | [343,430,518,465] | 6 | hSpCas9 | negative selection | 8490289 | 1716599 | 1716622 | 17 | - | 27260156 | RDES | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.030335113402792768 | [416] | [392,575,462,528] | 0 | hSpCas9 | negative selection | 8554536 | 1716622 | 1716645 | 17 | - | 27260156 | RDES | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.2582717533029141 | [560] | [498,506,435,735] | -4 | hSpCas9 | negative selection | 8554537 | 1725150 | 1725173 | 17 | - | 27260156 | PC3 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.08200221125935914 | [281] | [207,295,540,244] | 1 | hSpCas9 | negative selection | 8611540 | 1716599 | 1716622 | 17 | - | 27260156 | PC3 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.12238409815198453 | [416] | [283,324,485,479] | -3 | hSpCas9 | negative selection | 8675787 | 1716622 | 1716645 | 17 | - | 27260156 | PC3 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.5256073633232895 | [560] | [242,463,568,367] | -8 | hSpCas9 | negative selection | 8675788 | 1725150 | 1725173 | 17 | - | 27260156 | PATU8988T | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.4662045098088841 | [281] | [468,409,279,348] | 7 | hSpCas9 | negative selection | 8732791 | 1716599 | 1716622 | 17 | - | 27260156 | PATU8988T | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.07472677547678594 | [416] | [400,387,481,421] | 1 | hSpCas9 | negative selection | 8797038 | 1716622 | 1716645 | 17 | - | 27260156 | PATU8988T | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.0722261777558438 | [560] | [469,577,488,532] | -1 | hSpCas9 | negative selection | 8797039 | 1725150 | 1725173 | 17 | - | 27260156 | T47D | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.39269796697684173 | [281] | [457,425,409,431] | 8 | hSpCas9 | negative selection | 8854042 | 1716599 | 1716622 | 17 | - | 27260156 | T47D | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.2562882796813415 | [416] | [442,415,499,260] | -5 | hSpCas9 | negative selection | 8918289 | 1716622 | 1716645 | 17 | - | 27260156 | T47D | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.4113820127064409 | [560] | [477,465,490,533] | -7 | hSpCas9 | negative selection | 8918290 | 1725150 | 1725173 | 17 | - | 27260156 | SU8686 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.4620718822721964 | [281] | [333,362,370,495] | 7 | hSpCas9 | negative selection | 8975293 | 1716599 | 1716622 | 17 | - | 27260156 | SU8686 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.17776332488633279 | [416] | [321,373,272,515] | -3 | hSpCas9 | negative selection | 9039540 | 1716622 | 1716645 | 17 | - | 27260156 | SU8686 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.4283245517907125 | [560] | [303,487,416,449] | -6 | hSpCas9 | negative selection | 9039541 | 1725150 | 1725173 | 17 | - | 27260156 | SKES1 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.46832546552608245 | [281] | [353,531,371,315] | 8 | hSpCas9 | negative selection | 9096544 | 1716599 | 1716622 | 17 | - | 27260156 | SKES1 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.14301165401944066 | [416] | [425,400,366,324] | -3 | hSpCas9 | negative selection | 9160791 | 1716622 | 1716645 | 17 | - | 27260156 | SKES1 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.4741074680638818 | [560] | [570,354,388,319] | -8 | hSpCas9 | negative selection | 9160792 | 1725150 | 1725173 | 17 | - | 27260156 | TOV112D | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.24465994465280982 | [281] | [314,621,350,124] | 5 | hSpCas9 | negative selection | 9217795 | 1716599 | 1716622 | 17 | - | 27260156 | TOV112D | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.013197239412469641 | [416] | [396,640,342,357] | 0 | hSpCas9 | negative selection | 9282042 | 1716622 | 1716645 | 17 | - | 27260156 | TOV112D | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.5942552057160346 | [560] | [289,549,387,298] | -8 | hSpCas9 | negative selection | 9282043 | 1725150 | 1725173 | 17 | - | 27260156 | TC71 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.17609424462201517 | [281] | [294,390,271,415] | 4 | hSpCas9 | negative selection | 9339046 | 1716599 | 1716622 | 17 | - | 27260156 | TC71 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | -0.2818661470392665 | [416] | [357,423,325,363] | -6 | hSpCas9 | negative selection | 9403293 | 1716622 | 1716645 | 17 | - | 27260156 | TC71 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.6123488327963216 | [560] | [331,371,485,380] | -9 | hSpCas9 | negative selection | 9403294 | 1725150 | 1725173 | 17 | - | 27260156 | TC32 | viability | CAGCCGGCGATCGCGGAGGCTGG | WDR81 | ENSG00000167716 | 0.2725086893969588 | [281] | [228,354,386,296] | 5 | hSpCas9 | negative selection | 9460297 | 1716599 | 1716622 | 17 | - | 27260156 | TC32 | viability | GTTCTGGGAACGACGGTGTCAGG | WDR81 | ENSG00000167716 | 0.11695874825796915 | [416] | [510,419,344,367] | 2 | hSpCas9 | negative selection | 9524544 | 1716622 | 1716645 | 17 | - | 27260156 | TC32 | viability | TGCCAACTCACAGAGCGCGCTGG | WDR81 | ENSG00000167716 | -0.30656953582541346 | [560] | [429,371,534,376] | -5 | hSpCas9 | negative selection | 9524545 | 1716606 | 1716629 | 17 | - | 27869803 | HPAFII | viability after 27 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | -0.8545202699357809 | [851] | [316,189,NaN] | -6 | hSpCas9 | negative selection | 9559279 | 1725115 | 1725138 | 17 | - | 27869803 | HPAFII | viability after 27 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | 0.3634175117054006 | [456] | [55,519,NaN] | 3 | hSpCas9 | negative selection | 9559288 | 1716606 | 1716629 | 17 | - | 27869803 | HPAFII | viability after 15 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | -0.5791402441391593 | [851] | [771,513,NaN] | -6 | hSpCas9 | negative selection | 9641728 | 1725115 | 1725138 | 17 | - | 27869803 | HPAFII | viability after 15 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | 0.17804972039932232 | [456] | [374,667,NaN] | 2 | hSpCas9 | negative selection | 9641737 | 1716606 | 1716629 | 17 | - | 27869803 | ASPC1 | viability after 36 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.1307713197985867 | [2140] | [458,1380,614] | 1 | hSpCas9 | negative selection | 9724177 | 1725115 | 1725138 | 17 | - | 27869803 | ASPC1 | viability after 36 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | -0.13875909034537626 | [1121] | [496,468,162] | -1 | hSpCas9 | negative selection | 9724186 | 1716606 | 1716629 | 17 | - | 27869803 | PATU8988S | viability after 35 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.24166710878247577 | [2116] | [1053,961,NaN] | 2 | hSpCas9 | negative selection | 9806626 | 1725115 | 1725138 | 17 | - | 27869803 | PATU8988S | viability after 35 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | 0.07441264220233479 | [974] | [398,427,NaN] | 0 | hSpCas9 | negative selection | 9806635 | 1716606 | 1716629 | 17 | - | 27869803 | PATU8988S | viability after 31 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | 0.06147045563065512 | [2116] | [901,853,NaN] | 0 | hSpCas9 | negative selection | 9889075 | 1725115 | 1725138 | 17 | - | 27869803 | PATU8988S | viability after 31 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | 0.13187232600269894 | [974] | [359,509,NaN] | 1 | hSpCas9 | negative selection | 9889084 | 1716606 | 1716629 | 17 | - | 27869803 | HPAFII | viability after 35 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | -0.8570607517291063 | [851] | [247,226,NaN] | -5 | hSpCas9 | negative selection | 9971524 | 1725115 | 1725138 | 17 | - | 27869803 | HPAFII | viability after 35 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | 0.49544837414177345 | [456] | [42,644,NaN] | 3 | hSpCas9 | negative selection | 9971533 | 1716606 | 1716629 | 17 | - | 27869803 | HPAFII | viability after 31 days | GCGCTGGGTTCTGGGAACGACGG | WDR81 | ENSG00000167716 | -0.7654093119498104 | [851] | [365,188,NaN] | -5 | hSpCas9 | negative selection | 10053973 | 1725115 | 1725138 | 17 | - | 27869803 | HPAFII | viability after 31 days | CAGGCACTAGGGCCACCACGTGG | WDR81 | ENSG00000167716 | 0.5437468209673781 | [456] | [24,753,NaN] | 4 | hSpCas9 | negative selection | 10053982 |