| 48040600 | 48040623 | 18 | - | 26472758 | Jiyoye | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 1.3140659771143919 | [39] | [74] | 7 | hSpCas9 | negative selection | 184032 | 48040990 | 48041013 | 18 | - | 26472758 | Jiyoye | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 1.1998504082583672 | [126] | [219] | 7 | hSpCas9 | negative selection | 184033 | 48040945 | 48040968 | 18 | + | 26472758 | Jiyoye | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | -1.2302545391094184 | [27] | [8] | -7 | hSpCas9 | negative selection | 184034 | 48040787 | 48040810 | 18 | + | 26472758 | Jiyoye | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 1.5656047441103562 | [55] | [124] | 8 | hSpCas9 | negative selection | 184035 | 48040350 | 48040373 | 18 | + | 26472758 | Jiyoye | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | -0.5578181686662134 | [284] | [145] | -4 | hSpCas9 | negative selection | 184036 | 48040330 | 48040353 | 18 | + | 26472758 | Jiyoye | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | 1.4456495293205092 | [36] | [75] | 8 | hSpCas9 | negative selection | 184037 | 48040282 | 48040305 | 18 | - | 26472758 | Jiyoye | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | -0.7804516216698978 | [40] | [17] | -5 | hSpCas9 | negative selection | 184038 | 48040234 | 48040257 | 18 | - | 26472758 | Jiyoye | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | 1.4896375416978467 | [16] | [35] | 8 | hSpCas9 | negative selection | 184039 | 48039948 | 48039971 | 18 | + | 26472758 | Jiyoye | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | 0.04770121541413008 | [398] | [310] | 0 | hSpCas9 | negative selection | 184040 | 48041024 | 48041047 | 18 | - | 26472758 | Jiyoye | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | -0.06638819437942589 | [217] | [156] | 0 | hSpCas9 | negative selection | 184041 | 48040600 | 48040623 | 18 | - | 26472758 | KBM7 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.4153590762856941 | [351,412] | [167,309] | 4 | hSpCas9 | negative selection | 375150 | 48040990 | 48041013 | 18 | - | 26472758 | KBM7 | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.525639827725503 | [1170,1264] | [695,952] | 6 | hSpCas9 | negative selection | 375151 | 48040945 | 48040968 | 18 | + | 26472758 | KBM7 | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | 1.1360943509049077 | [51,55] | [31,77] | 9 | hSpCas9 | negative selection | 375152 | 48040787 | 48040810 | 18 | + | 26472758 | KBM7 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.1920966657919293 | [423,260] | [172,186] | 2 | hSpCas9 | negative selection | 375153 | 48040350 | 48040373 | 18 | + | 26472758 | KBM7 | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | -0.3048050717649002 | [572,557] | [196,232] | -3 | hSpCas9 | negative selection | 375154 | 48040330 | 48040353 | 18 | + | 26472758 | KBM7 | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | 0.09719038935095725 | [241,219] | [74,152] | 0 | hSpCas9 | negative selection | 375155 | 48040282 | 48040305 | 18 | - | 26472758 | KBM7 | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | -0.4159135394969464 | [100,79] | [18,42] | -4 | hSpCas9 | negative selection | 375156 | 48040234 | 48040257 | 18 | - | 26472758 | KBM7 | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | 1.044358073842139 | [117,266] | [119,261] | 9 | hSpCas9 | negative selection | 375157 | 48039948 | 48039971 | 18 | + | 26472758 | KBM7 | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | -0.06708779830596079 | [1630,1254] | [553,720] | 0 | hSpCas9 | negative selection | 375158 | 48041024 | 48041047 | 18 | - | 26472758 | KBM7 | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.2986781210073196 | [683,932] | [708,269] | 3 | hSpCas9 | negative selection | 375159 | 48040600 | 48040623 | 18 | - | 26472758 | Raji | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | -0.7651555554441422 | [248] | [33] | -5 | hSpCas9 | negative selection | 566268 | 48040990 | 48041013 | 18 | - | 26472758 | Raji | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.47866064912403017 | [568] | [183] | 4 | hSpCas9 | negative selection | 566269 | 48040945 | 48040968 | 18 | + | 26472758 | Raji | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | -0.8926164646264008 | [23] | [2] | -6 | hSpCas9 | negative selection | 566270 | 48040787 | 48040810 | 18 | + | 26472758 | Raji | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 1.8651826329569712 | [109] | [92] | 9 | hSpCas9 | negative selection | 566271 | 48040350 | 48040373 | 18 | + | 26472758 | Raji | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | 0.032836582008545334 | [277] | [65] | 0 | hSpCas9 | negative selection | 566272 | 48040330 | 48040353 | 18 | + | 26472758 | Raji | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | 0.2755062941819264 | [88] | [24] | 2 | hSpCas9 | negative selection | 566273 | 48040282 | 48040305 | 18 | - | 26472758 | Raji | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | 1.134350582973869 | [52] | [26] | 8 | hSpCas9 | negative selection | 566274 | 48040234 | 48040257 | 18 | - | 26472758 | Raji | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | 0.10738353537359946 | [95] | [23] | 1 | hSpCas9 | negative selection | 566275 | 48039948 | 48039971 | 18 | + | 26472758 | Raji | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | 0.2892218583594126 | [602] | [170] | 2 | hSpCas9 | negative selection | 566276 | 48041024 | 48041047 | 18 | - | 26472758 | Raji | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | -0.6896294424625458 | [416] | [59] | -5 | hSpCas9 | negative selection | 566277 | 48040600 | 48040623 | 18 | - | 26472758 | K562 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.7909610100737825 | [240] | [351] | 6 | hSpCas9 | negative selection | 757386 | 48040990 | 48041013 | 18 | - | 26472758 | K562 | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 1.1011294905552576 | [861] | [1560] | 8 | hSpCas9 | negative selection | 757387 | 48040945 | 48040968 | 18 | + | 26472758 | K562 | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | -3.2916341725737626 | [57] | [4] | -8 | hSpCas9 | negative selection | 757388 | 48040787 | 48040810 | 18 | + | 26472758 | K562 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 1.1434898188156661 | [258] | [482] | 8 | hSpCas9 | negative selection | 757389 | 48040350 | 48040373 | 18 | + | 26472758 | K562 | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | -1.170618771612397 | [519] | [194] | -6 | hSpCas9 | negative selection | 757390 | 48040330 | 48040353 | 18 | + | 26472758 | K562 | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | 0.3129501093372623 | [184] | [193] | 2 | hSpCas9 | negative selection | 757391 | 48040282 | 48040305 | 18 | - | 26472758 | K562 | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | 0.22478992091751415 | [73] | [72] | 1 | hSpCas9 | negative selection | 757392 | 48040234 | 48040257 | 18 | - | 26472758 | K562 | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | 1.0333951204091965 | [157] | [272] | 8 | hSpCas9 | negative selection | 757393 | 48039948 | 48039971 | 18 | + | 26472758 | K562 | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | 0.46845900188437706 | [999] | [1167] | 4 | hSpCas9 | negative selection | 757394 | 48041024 | 48041047 | 18 | - | 26472758 | K562 | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.25156669459705006 | [603] | [606] | 2 | hSpCas9 | negative selection | 757395 | 48029373 | 48029396 | 18 | - | 26627737 | DLD1 | viability | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 0.8961186600777995 | [69] | [47,68,10] | 8 | hSpCas9 | negative selection | 801615 | 48029754 | 48029777 | 18 | + | 26627737 | DLD1 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.10381379952675215 | [456] | [80,121,186] | -1 | hSpCas9 | negative selection | 801616 | 48040034 | 48040057 | 18 | + | 26627737 | DLD1 | viability | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.3948993452956355 | [581] | [262,158,284] | 4 | hSpCas9 | negative selection | 801617 | 48040035 | 48040058 | 18 | + | 26627737 | DLD1 | viability | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.18271284820996192 | [291] | [99,124,88] | 1 | hSpCas9 | negative selection | 801618 | 48040600 | 48040623 | 18 | - | 26627737 | DLD1 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.6299925451801556 | [361] | [170,152,196] | 6 | hSpCas9 | negative selection | 801619 | 48040787 | 48040810 | 18 | + | 26627737 | DLD1 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.8985507907514915 | [214] | [96,54,207] | 8 | hSpCas9 | negative selection | 801620 | 48029373 | 48029396 | 18 | - | 26627737 | GBM cells | viability after 5 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 0.5534173088599188 | [53] | [43,40] | 7 | hSpCas9 | negative selection | 883930 | 48029754 | 48029777 | 18 | + | 26627737 | GBM cells | viability after 5 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.005829078802197768 | [220] | [154,82] | 0 | hSpCas9 | negative selection | 883931 | 48040034 | 48040057 | 18 | + | 26627737 | GBM cells | viability after 5 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.48684183408340315 | [323] | [244,241] | 7 | hSpCas9 | negative selection | 883932 | 48040035 | 48040058 | 18 | + | 26627737 | GBM cells | viability after 5 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.22769564081411042 | [167] | [106,103] | 3 | hSpCas9 | negative selection | 883933 | 48040600 | 48040623 | 18 | - | 26627737 | GBM cells | viability after 5 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | -0.03758318280815626 | [199] | [105,102] | 0 | hSpCas9 | negative selection | 883934 | 48040787 | 48040810 | 18 | + | 26627737 | GBM cells | viability after 5 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.050157455261922834 | [189] | [96,113] | 0 | hSpCas9 | negative selection | 883935 | 48029373 | 48029396 | 18 | - | 26627737 | GBM cells | viability after 13 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 0.7214304353743313 | [53] | [44,50] | 8 | hSpCas9 | negative selection | 966245 | 48029754 | 48029777 | 18 | + | 26627737 | GBM cells | viability after 13 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.12781896602379364 | [220] | [149,76] | -1 | hSpCas9 | negative selection | 966246 | 48040034 | 48040057 | 18 | + | 26627737 | GBM cells | viability after 13 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.6398205426247636 | [323] | [306,246] | 7 | hSpCas9 | negative selection | 966247 | 48040035 | 48040058 | 18 | + | 26627737 | GBM cells | viability after 13 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.3614192018313141 | [167] | [190,56] | 4 | hSpCas9 | negative selection | 966248 | 48040600 | 48040623 | 18 | - | 26627737 | GBM cells | viability after 13 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.09073054501207006 | [199] | [130,102] | 1 | hSpCas9 | negative selection | 966249 | 48040787 | 48040810 | 18 | + | 26627737 | GBM cells | viability after 13 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.19489056460934084 | [189] | [117,117] | 2 | hSpCas9 | negative selection | 966250 | 48029373 | 48029396 | 18 | - | 26627737 | GBM cells | viability after 21 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | -0.15279550077181225 | [53] | [28,23] | -1 | hSpCas9 | negative selection | 1048560 | 48029754 | 48029777 | 18 | + | 26627737 | GBM cells | viability after 21 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.08763216225483314 | [220] | [124,101] | -1 | hSpCas9 | negative selection | 1048561 | 48040034 | 48040057 | 18 | + | 26627737 | GBM cells | viability after 21 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.5410093306054218 | [323] | [276,236] | 5 | hSpCas9 | negative selection | 1048562 | 48040035 | 48040058 | 18 | + | 26627737 | GBM cells | viability after 21 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | -0.1498480396222024 | [167] | [75,87] | -1 | hSpCas9 | negative selection | 1048563 | 48040600 | 48040623 | 18 | - | 26627737 | GBM cells | viability after 21 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | -0.2844713884153119 | [199] | [95,82] | -3 | hSpCas9 | negative selection | 1048564 | 48040787 | 48040810 | 18 | + | 26627737 | GBM cells | viability after 21 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | -0.30189215543218095 | [189] | [89,77] | -3 | hSpCas9 | negative selection | 1048565 | 48029373 | 48029396 | 18 | - | 26627737 | RPE1 | viability after 9 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 0.45453838188889883 | [186] | [67,95] | 3 | hSpCas9 | negative selection | 1130875 | 48029754 | 48029777 | 18 | + | 26627737 | RPE1 | viability after 9 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.16708956554810808 | [889] | [204,451] | 1 | hSpCas9 | negative selection | 1130876 | 48040034 | 48040057 | 18 | + | 26627737 | RPE1 | viability after 9 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.14703816402343461 | [1355] | [349,624] | 1 | hSpCas9 | negative selection | 1130877 | 48040035 | 48040058 | 18 | + | 26627737 | RPE1 | viability after 9 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.004952470360178651 | [321] | [84,121] | 0 | hSpCas9 | negative selection | 1130878 | 48040600 | 48040623 | 18 | - | 26627737 | RPE1 | viability after 9 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | -0.4953445482815103 | [750] | [154,181] | -4 | hSpCas9 | negative selection | 1130879 | 48040787 | 48040810 | 18 | + | 26627737 | RPE1 | viability after 9 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.984491111476913 | [409] | [208,311] | 6 | hSpCas9 | negative selection | 1130880 | 48029373 | 48029396 | 18 | - | 26627737 | RPE1 | viability after 12 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 0.1417748719150249 | [186] | [69,39] | 1 | hSpCas9 | negative selection | 1213190 | 48029754 | 48029777 | 18 | + | 26627737 | RPE1 | viability after 12 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.44198461096645225 | [889] | [335,312] | 3 | hSpCas9 | negative selection | 1213191 | 48040034 | 48040057 | 18 | + | 26627737 | RPE1 | viability after 12 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.14938547556315085 | [1355] | [371,437] | 1 | hSpCas9 | negative selection | 1213192 | 48040035 | 48040058 | 18 | + | 26627737 | RPE1 | viability after 12 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.7416882855233653 | [321] | [98,192] | 5 | hSpCas9 | negative selection | 1213193 | 48040600 | 48040623 | 18 | - | 26627737 | RPE1 | viability after 12 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | -0.6835368855734532 | [750] | [78,174] | -5 | hSpCas9 | negative selection | 1213194 | 48040787 | 48040810 | 18 | + | 26627737 | RPE1 | viability after 12 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 1.0327921316006368 | [409] | [220,229] | 6 | hSpCas9 | negative selection | 1213195 | 48029373 | 48029396 | 18 | - | 26627737 | RPE1 | viability after 15 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 0.0017275399781300216 | [186] | [26,77] | 0 | hSpCas9 | negative selection | 1295505 | 48029754 | 48029777 | 18 | + | 26627737 | RPE1 | viability after 15 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.0949994612928922 | [889] | [335,138] | 0 | hSpCas9 | negative selection | 1295506 | 48040034 | 48040057 | 18 | + | 26627737 | RPE1 | viability after 15 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | -0.1853647406070843 | [1355] | [177,490] | -1 | hSpCas9 | negative selection | 1295507 | 48040035 | 48040058 | 18 | + | 26627737 | RPE1 | viability after 15 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.8579057269915844 | [321] | [103,223] | 5 | hSpCas9 | negative selection | 1295508 | 48040600 | 48040623 | 18 | - | 26627737 | RPE1 | viability after 15 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | -0.5345378473512058 | [750] | [52,236] | -3 | hSpCas9 | negative selection | 1295509 | 48040787 | 48040810 | 18 | + | 26627737 | RPE1 | viability after 15 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.4703852083001106 | [409] | [121,197] | 3 | hSpCas9 | negative selection | 1295510 | 48029373 | 48029396 | 18 | - | 26627737 | RPE1 | viability after 18 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 0.4596966698104663 | [186] | [51,87] | 3 | hSpCas9 | negative selection | 1377820 | 48029754 | 48029777 | 18 | + | 26627737 | RPE1 | viability after 18 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.17816182966768343 | [889] | [249,294] | 1 | hSpCas9 | negative selection | 1377821 | 48040034 | 48040057 | 18 | + | 26627737 | RPE1 | viability after 18 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | -0.005482493851680537 | [1355] | [336,393] | 0 | hSpCas9 | negative selection | 1377822 | 48040035 | 48040058 | 18 | + | 26627737 | RPE1 | viability after 18 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.622951392491656 | [321] | [84,185] | 4 | hSpCas9 | negative selection | 1377823 | 48040600 | 48040623 | 18 | - | 26627737 | RPE1 | viability after 18 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.08098803680891765 | [750] | [64,373] | 0 | hSpCas9 | negative selection | 1377824 | 48040787 | 48040810 | 18 | + | 26627737 | RPE1 | viability after 18 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.72700845174778 | [409] | [128,240] | 4 | hSpCas9 | negative selection | 1377825 | 48029373 | 48029396 | 18 | - | 26627737 | HeLa | viability after 8 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | -0.7238959630378314 | [104] | [23,12,43] | -6 | hSpCas9 | negative selection | 1460135 | 48029754 | 48029777 | 18 | + | 26627737 | HeLa | viability after 8 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 1.0802009800380514 | [454] | [745,416,181] | 8 | hSpCas9 | negative selection | 1460136 | 48040034 | 48040057 | 18 | + | 26627737 | HeLa | viability after 8 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.0678321689937893 | [500] | [262,229,201] | 0 | hSpCas9 | negative selection | 1460137 | 48040035 | 48040058 | 18 | + | 26627737 | HeLa | viability after 8 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | -0.34782910555536195 | [163] | [53,75,38] | -3 | hSpCas9 | negative selection | 1460138 | 48040600 | 48040623 | 18 | - | 26627737 | HeLa | viability after 8 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.3136547604371452 | [305] | [118,227,140] | 3 | hSpCas9 | negative selection | 1460139 | 48040787 | 48040810 | 18 | + | 26627737 | HeLa | viability after 8 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.27762151996958995 | [200] | [48,216,43] | 2 | hSpCas9 | negative selection | 1460140 | 48029373 | 48029396 | 18 | - | 26627737 | HeLa | viability after 12 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 0.07403188306903719 | [104] | [52,47,35] | 0 | hSpCas9 | negative selection | 1542450 | 48029754 | 48029777 | 18 | + | 26627737 | HeLa | viability after 12 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.019608010407858867 | [454] | [166,257,138] | 0 | hSpCas9 | negative selection | 1542451 | 48040034 | 48040057 | 18 | + | 26627737 | HeLa | viability after 12 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.08429301420417695 | [500] | [241,154,268] | 0 | hSpCas9 | negative selection | 1542452 | 48040035 | 48040058 | 18 | + | 26627737 | HeLa | viability after 12 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.9148249024607094 | [163] | [166,103,115] | 7 | hSpCas9 | negative selection | 1542453 | 48040600 | 48040623 | 18 | - | 26627737 | HeLa | viability after 12 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.6693666417588611 | [305] | [247,188,168] | 5 | hSpCas9 | negative selection | 1542454 | 48040787 | 48040810 | 18 | + | 26627737 | HeLa | viability after 12 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.8953078486326084 | [200] | [250,81,140] | 7 | hSpCas9 | negative selection | 1542455 | 48029373 | 48029396 | 18 | - | 26627737 | HeLa | viability after 15 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | -0.038465906585470444 | [104] | [56,21,45] | 0 | hSpCas9 | negative selection | 1624765 | 48029754 | 48029777 | 18 | + | 26627737 | HeLa | viability after 15 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.1788433131633237 | [454] | [149,105,240] | -1 | hSpCas9 | negative selection | 1624766 | 48040034 | 48040057 | 18 | + | 26627737 | HeLa | viability after 15 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.012385534152645872 | [500] | [194,207,214] | 0 | hSpCas9 | negative selection | 1624767 | 48040035 | 48040058 | 18 | + | 26627737 | HeLa | viability after 15 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.15709871584639745 | [163] | [55,87,79] | 1 | hSpCas9 | negative selection | 1624768 | 48040600 | 48040623 | 18 | - | 26627737 | HeLa | viability after 15 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.027469480758537834 | [305] | [163,154,55] | 0 | hSpCas9 | negative selection | 1624769 | 48040787 | 48040810 | 18 | + | 26627737 | HeLa | viability after 15 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.26352742160132203 | [200] | [119,80,92] | 2 | hSpCas9 | negative selection | 1624770 | 48029373 | 48029396 | 18 | - | 26627737 | HeLa | viability after 18 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | -0.02107921572108129 | [104] | [40,15,45] | 0 | hSpCas9 | negative selection | 1707080 | 48029754 | 48029777 | 18 | + | 26627737 | HeLa | viability after 18 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.14418879654193162 | [454] | [108,86,240] | -1 | hSpCas9 | negative selection | 1707081 | 48040034 | 48040057 | 18 | + | 26627737 | HeLa | viability after 18 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.027370149246630282 | [500] | [135,170,214] | 0 | hSpCas9 | negative selection | 1707082 | 48040035 | 48040058 | 18 | + | 26627737 | HeLa | viability after 18 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.19187290171147264 | [163] | [40,72,79] | 1 | hSpCas9 | negative selection | 1707083 | 48040600 | 48040623 | 18 | - | 26627737 | HeLa | viability after 18 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | -0.04631734340533178 | [305] | [101,122,55] | 0 | hSpCas9 | negative selection | 1707084 | 48040787 | 48040810 | 18 | + | 26627737 | HeLa | viability after 18 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.2561679885003256 | [200] | [77,68,92] | 2 | hSpCas9 | negative selection | 1707085 | 48029373 | 48029396 | 18 | - | 26627737 | HCT116 | viability after 6 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | -0.4132728814001019 | [152] | [48,0] | -2 | hSpCas9 | negative selection | 1789395 | 48029754 | 48029777 | 18 | + | 26627737 | HCT116 | viability after 6 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 1.432856149426958 | [448] | [245,159] | 7 | hSpCas9 | negative selection | 1789396 | 48040034 | 48040057 | 18 | + | 26627737 | HCT116 | viability after 6 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | -0.2750150806281057 | [584] | [182,16] | -1 | hSpCas9 | negative selection | 1789397 | 48040035 | 48040058 | 18 | + | 26627737 | HCT116 | viability after 6 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.12536565136872357 | [312] | [14,74] | 0 | hSpCas9 | negative selection | 1789398 | 48040600 | 48040623 | 18 | - | 26627737 | HCT116 | viability after 6 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.0843123040893522 | [939] | [418,11] | 0 | hSpCas9 | negative selection | 1789399 | 48040787 | 48040810 | 18 | + | 26627737 | HCT116 | viability after 6 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | -0.5622581541994577 | [352] | [5,54] | -3 | hSpCas9 | negative selection | 1789400 | 48029373 | 48029396 | 18 | - | 26627737 | HCT116 | viability after 8 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 1.5949950476227455 | [30] | [65,31,56] | 9 | hSpCas9 | negative selection | 1871710 | 48029754 | 48029777 | 18 | + | 26627737 | HCT116 | viability after 8 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.06431204714375227 | [239] | [139,65,207] | 0 | hSpCas9 | negative selection | 1871711 | 48040034 | 48040057 | 18 | + | 26627737 | HCT116 | viability after 8 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.010010733041421305 | [431] | [306,230,182] | 0 | hSpCas9 | negative selection | 1871712 | 48040035 | 48040058 | 18 | + | 26627737 | HCT116 | viability after 8 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.6023090052574934 | [104] | [100,95,66] | 6 | hSpCas9 | negative selection | 1871713 | 48040600 | 48040623 | 18 | - | 26627737 | HCT116 | viability after 8 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.7513509366610035 | [207] | [193,205,178] | 7 | hSpCas9 | negative selection | 1871714 | 48040787 | 48040810 | 18 | + | 26627737 | HCT116 | viability after 8 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | -0.3568195837774047 | [248] | [85,123,110] | -4 | hSpCas9 | negative selection | 1871715 | 48029373 | 48029396 | 18 | - | 26627737 | HCT116 | viability after 9 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | -2.6710804667228913 | [152] | [11,1] | -9 | hSpCas9 | negative selection | 1954025 | 48029754 | 48029777 | 18 | + | 26627737 | HCT116 | viability after 9 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 1.4550181435715865 | [448] | [364,299] | 8 | hSpCas9 | negative selection | 1954026 | 48040034 | 48040057 | 18 | + | 26627737 | HCT116 | viability after 9 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.2812522941378913 | [584] | [324,82] | 2 | hSpCas9 | negative selection | 1954027 | 48040035 | 48040058 | 18 | + | 26627737 | HCT116 | viability after 9 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | -1.859772780982261 | [312] | [17,26] | -8 | hSpCas9 | negative selection | 1954028 | 48040600 | 48040623 | 18 | - | 26627737 | HCT116 | viability after 9 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | -0.9950726702041035 | [939] | [97,147] | -6 | hSpCas9 | negative selection | 1954029 | 48040787 | 48040810 | 18 | + | 26627737 | HCT116 | viability after 9 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.7106974395834192 | [352] | [332,12] | 5 | hSpCas9 | negative selection | 1954030 | 48029373 | 48029396 | 18 | - | 26627737 | HCT116 | viability after 12 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 1.6384594728257205 | [30] | [35,31,84] | 9 | hSpCas9 | negative selection | 2036340 | 48029754 | 48029777 | 18 | + | 26627737 | HCT116 | viability after 12 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.5132134074682504 | [239] | [192,101,241] | 5 | hSpCas9 | negative selection | 2036341 | 48040034 | 48040057 | 18 | + | 26627737 | HCT116 | viability after 12 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.20673621827122723 | [431] | [221,239,326] | 2 | hSpCas9 | negative selection | 2036342 | 48040035 | 48040058 | 18 | + | 26627737 | HCT116 | viability after 12 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.7411335342375375 | [104] | [36,151,93] | 6 | hSpCas9 | negative selection | 2036343 | 48040600 | 48040623 | 18 | - | 26627737 | HCT116 | viability after 12 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.533549271861227 | [207] | [129,151,194] | 5 | hSpCas9 | negative selection | 2036344 | 48040787 | 48040810 | 18 | + | 26627737 | HCT116 | viability after 12 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | -0.17100545610516898 | [248] | [46,166,141] | -2 | hSpCas9 | negative selection | 2036345 | 48029373 | 48029396 | 18 | - | 26627737 | HCT116 | viability after 15 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 2.3816919498775624 | [30] | [92,61,122] | 9 | hSpCas9 | negative selection | 2118655 | 48029754 | 48029777 | 18 | + | 26627737 | HCT116 | viability after 15 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.5462817445489159 | [239] | [368,116,138] | 5 | hSpCas9 | negative selection | 2118656 | 48040034 | 48040057 | 18 | + | 26627737 | HCT116 | viability after 15 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.5515041101184244 | [431] | [314,329,438] | 5 | hSpCas9 | negative selection | 2118657 | 48040035 | 48040058 | 18 | + | 26627737 | HCT116 | viability after 15 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.8494904961409592 | [104] | [109,96,118] | 7 | hSpCas9 | negative selection | 2118658 | 48040600 | 48040623 | 18 | - | 26627737 | HCT116 | viability after 15 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.4073519492271902 | [207] | [190,109,177] | 4 | hSpCas9 | negative selection | 2118659 | 48040787 | 48040810 | 18 | + | 26627737 | HCT116 | viability after 15 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | -0.6820626171553945 | [248] | [101,81,84] | -6 | hSpCas9 | negative selection | 2118660 | 48029373 | 48029396 | 18 | - | 26627737 | HCT116 | viability after 18 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 2.1991104559967245 | [30] | [45,64,96] | 9 | hSpCas9 | negative selection | 2200970 | 48029754 | 48029777 | 18 | + | 26627737 | HCT116 | viability after 18 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.8628241557732766 | [239] | [305,137,192] | 7 | hSpCas9 | negative selection | 2200971 | 48040034 | 48040057 | 18 | + | 26627737 | HCT116 | viability after 18 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.2568263539254063 | [431] | [207,194,353] | 2 | hSpCas9 | negative selection | 2200972 | 48040035 | 48040058 | 18 | + | 26627737 | HCT116 | viability after 18 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.2340354774103941 | [104] | [47,73,55] | 2 | hSpCas9 | negative selection | 2200973 | 48040600 | 48040623 | 18 | - | 26627737 | HCT116 | viability after 18 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.4483828461676147 | [207] | [110,161,136] | 4 | hSpCas9 | negative selection | 2200974 | 48040787 | 48040810 | 18 | + | 26627737 | HCT116 | viability after 18 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | -0.4715848226508767 | [248] | [80,92,85] | -4 | hSpCas9 | negative selection | 2200975 | 48137384 | 48137407 | 18 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | AAAAACAAAACGGAGGAACCCGG | ZBTB7C | ENSG00000184828 | 0.23185556174725974 | [51,48] | [4,20] | 1 | dCas9-VP64 | positive selection | 2391576 | 48137427 | 48137450 | 18 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | ATTTTGTGAAGTACTAGAGAAGG | ZBTB7C | ENSG00000184828 | -0.804029697890234 | [53,87] | [7,8] | -4 | dCas9-VP64 | positive selection | 2391577 | 48137453 | 48137476 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TTACCACTTATCTCAAAGCAAGG | ZBTB7C | ENSG00000184828 | -2.150076694078781 | [134,267] | [4,13] | -9 | dCas9-VP64 | positive selection | 2391578 | 48214502 | 48214525 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | ACAGGATGCAGTAAAGAAGCTGG | ZBTB7C | ENSG00000184828 | 4.925679733304566 | [16,9] | [174,7] | 9 | dCas9-VP64 | positive selection | 2397761 | 48358162 | 48358185 | 18 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | AGACGGGGTTTCACCATTGTTGG | ZBTB7C | ENSG00000184828 | 0.8018218592524771 | [428,460] | [286,44] | 3 | dCas9-VP64 | positive selection | 2413528 | 48301249 | 48301272 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGGGGGGATCACCTGAGGTCAGG | ZBTB7C | ENSG00000184828 | 2.0756360988061657 | [163,24] | [148,19] | 7 | dCas9-VP64 | positive selection | 2422630 | 48346969 | 48346992 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GAGATGGGTTTTCACCATGTTGG | ZBTB7C | ENSG00000184828 | 3.916189069033361 | [314,93] | [113,1282] | 9 | dCas9-VP64 | positive selection | 2433966 | 48228730 | 48228753 | 18 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GTGTGAGAGAGAGAGAGAGACAG | ZBTB7C | ENSG00000184828 | 3.246472249107505 | [0,4] | [1,12] | 8 | dCas9-VP64 | positive selection | 2458413 | 48137384 | 48137407 | 18 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | AAAAACAAAACGGAGGAACCCGG | ZBTB7C | ENSG00000184828 | 2.209759786988247 | [14,30] | [11,56] | 8 | dCas9-VP64 | positive selection | 2486831 | 48137427 | 48137450 | 18 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | ATTTTGTGAAGTACTAGAGAAGG | ZBTB7C | ENSG00000184828 | 0.7295882251935086 | [130,79] | [109,7] | 5 | dCas9-VP64 | positive selection | 2486832 | 48137453 | 48137476 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TTACCACTTATCTCAAAGCAAGG | ZBTB7C | ENSG00000184828 | -1.1808627199597361 | [35,400] | [26,33] | -9 | dCas9-VP64 | positive selection | 2486833 | 48214502 | 48214525 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | ACAGGATGCAGTAAAGAAGCTGG | ZBTB7C | ENSG00000184828 | 0.38906795686834106 | [19,135] | [18,44] | 3 | dCas9-VP64 | positive selection | 2493016 | 48358162 | 48358185 | 18 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | AGACGGGGTTTCACCATTGTTGG | ZBTB7C | ENSG00000184828 | 0.171897966735983 | [521,305] | [149,154] | 1 | dCas9-VP64 | positive selection | 2508783 | 48301249 | 48301272 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGGGGGGATCACCTGAGGTCAGG | ZBTB7C | ENSG00000184828 | 1.4214284980238518 | [47,35] | [16,54] | 7 | dCas9-VP64 | positive selection | 2517885 | 48346969 | 48346992 | 18 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GAGATGGGTTTTCACCATGTTGG | ZBTB7C | ENSG00000184828 | 2.0642303287003654 | [37,60] | [95,40] | 8 | dCas9-VP64 | positive selection | 2529221 | 48228730 | 48228753 | 18 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GTGTGAGAGAGAGAGAGAGACAG | ZBTB7C | ENSG00000184828 | 2.8702956375825326 | [127,55] | [142,294] | 9 | dCas9-VP64 | positive selection | 2553668 | 48040873 | 48040896 | 18 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | AAGTCGATCTCATAGACGTAGGG | ZBTB7C | ENSG00000184828 | -0.1257740537617585 | [2,2] | [1,1] | -2 | hSpCas9 | positive selection | 3033280 | 48040788 | 48040811 | 18 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | -0.3391923414027257 | [3,4] | [3,1] | -5 | hSpCas9 | positive selection | 3033281 | 48040990 | 48041013 | 18 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.1679928621677037 | [5,5] | [6,4] | 3 | hSpCas9 | positive selection | 3033282 | 48041024 | 48041047 | 18 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.3000249903791899 | [4,4] | [4,4] | 6 | hSpCas9 | positive selection | 3033283 | 48040873 | 48040896 | 18 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | AAGTCGATCTCATAGACGTAGGG | ZBTB7C | ENSG00000184828 | -0.6127536273242148 | [2,2] | [1,0] | -8 | hSpCas9 | positive selection | 3101138 | 48040788 | 48040811 | 18 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.03952764703466927 | [3,3] | [4,1] | 0 | hSpCas9 | positive selection | 3101139 | 48040990 | 48041013 | 18 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.2818452740585502 | [5,5] | [5,3] | 5 | hSpCas9 | positive selection | 3101140 | 48041024 | 48041047 | 18 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.5635338285456477 | [4,4] | [4,4] | 8 | hSpCas9 | positive selection | 3101141 | 48040115 | 48040138 | | + | 24336571 | A375 | resistance to PLX after 7 days | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.22036617881732062 | [14,14] | [18,15] | 6 | hSpCas9 | positive selection | 3156414 | 48029818 | 48029841 | | + | 24336571 | A375 | resistance to PLX after 7 days | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.08333758374924183 | [36,34] | [33,32] | -2 | hSpCas9 | positive selection | 3156415 | 48040735 | 48040758 | | - | 24336571 | A375 | resistance to PLX after 7 days | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | -0.15748183301154084 | [32,31] | [30,26] | -5 | hSpCas9 | positive selection | 3156416 | 48029754 | 48029777 | | + | 24336571 | A375 | resistance to PLX after 7 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.7304805595380922 | [10,14] | [7,7] | -9 | hSpCas9 | positive selection | 3156417 | 48040115 | 48040138 | | + | 24336571 | A375 | resistance to PLX after 14 days | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | -0.008641755402441498 | [21,21] | [8,10] | 0 | hSpCas9 | positive selection | 3214207 | 48029818 | 48029841 | | + | 24336571 | A375 | resistance to PLX after 14 days | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.060838237166910725 | [33,33] | [13,15] | 0 | hSpCas9 | positive selection | 3214208 | 48040735 | 48040758 | | - | 24336571 | A375 | resistance to PLX after 14 days | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | -0.24782147945179034 | [25,35] | [11,11] | -3 | hSpCas9 | positive selection | 3214209 | 48029754 | 48029777 | | + | 24336571 | A375 | resistance to PLX after 14 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -1.0672919800043528 | [12,12] | [2,1] | -9 | hSpCas9 | positive selection | 3214210 | 48040115 | 48040138 | | + | 24336571 | A375 | viability after 7 days | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.2584063363005663 | [12] | [14,14] | 4 | hSpCas9 | negative selection | 3272000 | 48029818 | 48029841 | | + | 24336571 | A375 | viability after 7 days | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.4350209259134903 | [27] | [36,34] | 6 | hSpCas9 | negative selection | 3272001 | 48040735 | 48040758 | | - | 24336571 | A375 | viability after 7 days | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.623811357589115 | [21] | [32,31] | 8 | hSpCas9 | negative selection | 3272002 | 48029754 | 48029777 | | + | 24336571 | A375 | viability after 7 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.2463187738802932 | [16] | [10,14] | -3 | hSpCas9 | negative selection | 3272003 | 48040115 | 48040138 | | + | 24336571 | A375 | viability after 14 days | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.8117627873245158 | [12] | [21,21] | 8 | hSpCas9 | negative selection | 3329793 | 48029818 | 48029841 | | + | 24336571 | A375 | viability after 14 days | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.3525080282112154 | [27] | [33,33] | 4 | hSpCas9 | negative selection | 3329794 | 48040735 | 48040758 | | - | 24336571 | A375 | viability after 14 days | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.5768824970463499 | [21] | [25,35] | 7 | hSpCas9 | negative selection | 3329795 | 48029754 | 48029777 | | + | 24336571 | A375 | viability after 14 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.25432691047721795 | [16] | [12,12] | -3 | hSpCas9 | negative selection | 3329796 | 48029362 | 48029385 | 18 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.9293993759370296 | [240,240] | [2,2] | 4 | hSpCas9 | positive selection | 3402027 | 48040793 | 48040816 | 18 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 1.672363710724679 | [47,47] | [0,0] | 6 | hSpCas9 | positive selection | 3402028 | 48029754 | 48029777 | 18 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.5305763479455964 | [220,220] | [0,0] | -4 | hSpCas9 | positive selection | 3402029 | 48040872 | 48040895 | 18 | + | 26780180 | HT29 | viability (Avana library 4 designs) | AAGTCGATCTCATAGACGTAGGG | ZBTB7C | ENSG00000184828 | 1.48652065490951 | [] | [] | 6 | hSpCas9 | negative selection | 3472580 | 48040787 | 48040810 | 18 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | -0.521586365752457 | [] | [] | -7 | hSpCas9 | negative selection | 3472581 | 48040990 | 48041013 | 18 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | -0.444338774212351 | [] | [] | -6 | hSpCas9 | negative selection | 3472582 | 48041024 | 48041047 | 18 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.46159400706802 | [] | [] | 1 | hSpCas9 | negative selection | 3472583 | 48041024 | 48041047 | 18 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.89112823020186 | [] | [] | 1 | hSpCas9 | negative selection | 3579934 | 48040787 | 48040810 | 18 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 4.08314000898673 | [] | [] | 6 | hSpCas9 | negative selection | 3579935 | 48040872 | 48040895 | 18 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AAGTCGATCTCATAGACGTAGGG | ZBTB7C | ENSG00000184828 | -0.458780620387772 | [] | [] | 0 | hSpCas9 | negative selection | 3579936 | 48040990 | 48041013 | 18 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 5.53968330956162 | [] | [] | 8 | hSpCas9 | negative selection | 3579937 | 48040492 | 48040515 | 18 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGCCTATTCAGACACCCCCAGGG | ZBTB7C | ENSG00000184828 | 2.52493668491848 | [] | [] | 4 | hSpCas9 | negative selection | 3579938 | 48040182 | 48040205 | 18 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AAGTCATTAGGGAAGGGTGGCGG | ZBTB7C | ENSG00000184828 | 3.81066071761007 | [] | [] | 6 | hSpCas9 | negative selection | 3579939 | 48041024 | 48041047 | 18 | - | 26780180 | A375 | viability (Avana lentiGuide) | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 2.20691010946574 | [] | [] | 2 | hSpCas9 | negative selection | 3688593 | 48040787 | 48040810 | 18 | + | 26780180 | A375 | viability (Avana lentiGuide) | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | -1.68164020270823 | [] | [] | -3 | hSpCas9 | negative selection | 3688594 | 48040872 | 48040895 | 18 | + | 26780180 | A375 | viability (Avana lentiGuide) | AAGTCGATCTCATAGACGTAGGG | ZBTB7C | ENSG00000184828 | -0.12986244821896 | [] | [] | 0 | hSpCas9 | negative selection | 3688595 | 48040990 | 48041013 | 18 | - | 26780180 | A375 | viability (Avana lentiGuide) | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | -2.56949832609417 | [] | [] | -4 | hSpCas9 | negative selection | 3688596 | 48040492 | 48040515 | 18 | - | 26780180 | A375 | viability (Avana lentiGuide) | GGCCTATTCAGACACCCCCAGGG | ZBTB7C | ENSG00000184828 | 13.5180871417989 | [] | [] | 7 | hSpCas9 | negative selection | 3688597 | 48040182 | 48040205 | 18 | + | 26780180 | A375 | viability (Avana lentiGuide) | AAGTCATTAGGGAAGGGTGGCGG | ZBTB7C | ENSG00000184828 | 7.80234765586545 | [] | [] | 6 | hSpCas9 | negative selection | 3688598 | 48041024 | 48041047 | 18 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.041657583283770394 | [6] | [6,5] | 1 | hSpCas9 | positive selection | 3797200 | 48040787 | 48040810 | 18 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.26957962811118513 | [4] | [6,5] | 7 | hSpCas9 | positive selection | 3797201 | 48040872 | 48040895 | 18 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AAGTCGATCTCATAGACGTAGGG | ZBTB7C | ENSG00000184828 | -0.23750519126217084 | [5] | [5,4] | -4 | hSpCas9 | positive selection | 3797202 | 48040990 | 48041013 | 18 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.35020881627731937 | [6] | [7,8] | 9 | hSpCas9 | positive selection | 3797203 | 48040492 | 48040515 | 18 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGCCTATTCAGACACCCCCAGGG | ZBTB7C | ENSG00000184828 | 0.18544240488828484 | [4] | [4,4] | 5 | hSpCas9 | positive selection | 3797204 | 48040182 | 48040205 | 18 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AAGTCATTAGGGAAGGGTGGCGG | ZBTB7C | ENSG00000184828 | 0.12472062668473431 | [4] | [5,4] | 3 | hSpCas9 | positive selection | 3797205 | 48041024 | 48041047 | 18 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.05885299924266452 | [6] | [4,6] | 1 | hSpCas9 | positive selection | 3905807 | 48040787 | 48040810 | 18 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | -0.36000833040580643 | [5] | [3,3] | -5 | hSpCas9 | positive selection | 3905808 | 48040872 | 48040895 | 18 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AAGTCGATCTCATAGACGTAGGG | ZBTB7C | ENSG00000184828 | 0.20039521373894853 | [4] | [5,3] | 5 | hSpCas9 | positive selection | 3905809 | 48040990 | 48041013 | 18 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.2380142746406796 | [7] | [7,7] | 6 | hSpCas9 | positive selection | 3905810 | 48040492 | 48040515 | 18 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGCCTATTCAGACACCCCCAGGG | ZBTB7C | ENSG00000184828 | 0.06475982934194777 | [5] | [3,5] | 1 | hSpCas9 | positive selection | 3905811 | 48040182 | 48040205 | 18 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AAGTCATTAGGGAAGGGTGGCGG | ZBTB7C | ENSG00000184828 | -0.2505387347503085 | [4] | [2,3] | -3 | hSpCas9 | positive selection | 3905812 | 48029362 | 48029385 | 18 | + | 26780180 | A375 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.609344008920222 | [] | [] | 2 | hSpCas9 | negative selection | 4013897 | 48040793 | 48040816 | 18 | + | 26780180 | A375 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.571487254625929 | [] | [] | 1 | hSpCas9 | negative selection | 4013898 | 48040115 | 48040138 | 18 | + | 26780180 | A375 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.0932177312641178 | [] | [] | 0 | hSpCas9 | negative selection | 4013899 | 48029818 | 48029841 | 18 | + | 26780180 | A375 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 1.58027475730094 | [] | [] | 8 | hSpCas9 | negative selection | 4013900 | 48040735 | 48040758 | 18 | - | 26780180 | A375 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.585282443832437 | [] | [] | 1 | hSpCas9 | negative selection | 4013901 | 48029754 | 48029777 | 18 | + | 26780180 | A375 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 1.41953861745829 | [] | [] | 7 | hSpCas9 | negative selection | 4013902 | 48029362 | 48029385 | 18 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.442178022403473 | [] | [] | 1 | hSpCas9 | negative selection | 4121863 | 48040793 | 48040816 | 18 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.531161513855811 | [] | [] | 1 | hSpCas9 | negative selection | 4121864 | 48040115 | 48040138 | 18 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.242395731473939 | [] | [] | 0 | hSpCas9 | negative selection | 4121865 | 48029818 | 48029841 | 18 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 1.45075391978293 | [] | [] | 7 | hSpCas9 | negative selection | 4121866 | 48040735 | 48040758 | 18 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 1.74644937353491 | [] | [] | 8 | hSpCas9 | negative selection | 4121867 | 48029754 | 48029777 | 18 | + | 26780180 | HT29 | viability (GeCKOv2 library) | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 1.56999153609282 | [] | [] | 8 | hSpCas9 | negative selection | 4121868 | 48040115 | 48040138 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.24242519318073721 | [4] | [3,3] | 6 | hSpCas9 | positive selection | 4183297 | 48029818 | 48029841 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.10624528788553045 | [4] | [3,3] | 2 | hSpCas9 | positive selection | 4183298 | 48040735 | 48040758 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.09792807848330706 | [4] | [2,3] | 2 | hSpCas9 | positive selection | 4183299 | 48029754 | 48029777 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.7083632899098224 | [3] | [6,0] | 9 | hSpCas9 | positive selection | 4183300 | 48040115 | 48040138 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 1.084205474799466 | [3] | [2,1,2,3] | 7 | hSpCas9 | positive selection | 4247319 | 48029818 | 48029841 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.7101645018173735 | [4] | [1,2,2,3] | 4 | hSpCas9 | positive selection | 4247320 | 48040735 | 48040758 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.932955342838739 | [3] | [0,2,2,3] | 6 | hSpCas9 | positive selection | 4247321 | 48029754 | 48029777 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.3471918839480558 | [3] | [0,3,0,0] | -5 | hSpCas9 | positive selection | 4247322 | 48029818 | 48029841 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.4428063292948818 | [3] | [2,0] | -7 | hSpCas9 | positive selection | 4308539 | 48040115 | 48040138 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.37604901790245476 | [3] | [4,3] | 7 | hSpCas9 | positive selection | 4308540 | 48040735 | 48040758 | 18 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.09309341474893862 | [3] | [3,3] | 2 | hSpCas9 | positive selection | 4308541 | 48029362 | 48029385 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.19999835929311005 | [3] | [3,2] | 4 | hSpCas9 | positive selection | 4372786 | 48040793 | 48040816 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | -0.1621902084960155 | [1] | [1,0] | -3 | hSpCas9 | positive selection | 4372787 | 48029754 | 48029777 | 18 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.060156538664477316 | [3] | [2,2] | -1 | hSpCas9 | positive selection | 4372788 | 48040339 | 48040361 | 18 | + | 27760321 | OCIAML3 | viability | GAAAGAAGTCCGGGGCGAATGG | ZBTB7C | ENSG00000184828 | -2.1241052622333982 | [267,255] | [63,24] | -9 | hSpCas9 | negative selection | 4455190 | 48040411 | 48040433 | 18 | - | 27760321 | OCIAML3 | viability | TCCATCGAATCTCTGCTAAGGG | ZBTB7C | ENSG00000184828 | 1.2436001382898643 | [211,177] | [347,374] | 9 | hSpCas9 | negative selection | 4455191 | 48040508 | 48040530 | 18 | + | 27760321 | OCIAML3 | viability | ATAGGCCTTCTCTGTGAGATGG | ZBTB7C | ENSG00000184828 | 0.07854637725758717 | [321,244] | [220,246] | 0 | hSpCas9 | negative selection | 4455192 | 48040772 | 48040794 | 18 | - | 27760321 | OCIAML3 | viability | GCACATCCTCAACGCAGCCAGG | ZBTB7C | ENSG00000184828 | 0.3529766526038781 | [834,651] | [566,959] | 4 | hSpCas9 | negative selection | 4455193 | 48040877 | 48040899 | 18 | + | 27760321 | OCIAML3 | viability | GATCTCATAGACGTAGGGCTGG | ZBTB7C | ENSG00000184828 | 0.12353556254868145 | [542,488] | [311,604] | 1 | hSpCas9 | negative selection | 4455194 | 48040339 | 48040361 | 18 | + | 27760321 | OCIAML2 | viability | GAAAGAAGTCCGGGGCGAATGG | ZBTB7C | ENSG00000184828 | 0.6552044592744369 | [267,255] | [338,327] | 8 | hSpCas9 | negative selection | 4538653 | 48040411 | 48040433 | 18 | - | 27760321 | OCIAML2 | viability | TCCATCGAATCTCTGCTAAGGG | ZBTB7C | ENSG00000184828 | 0.5575541929859488 | [211,177] | [191,282] | 7 | hSpCas9 | negative selection | 4538654 | 48040508 | 48040530 | 18 | + | 27760321 | OCIAML2 | viability | ATAGGCCTTCTCTGTGAGATGG | ZBTB7C | ENSG00000184828 | -0.17068274122293992 | [321,244] | [117,312] | -2 | hSpCas9 | negative selection | 4538655 | 48040772 | 48040794 | 18 | - | 27760321 | OCIAML2 | viability | GCACATCCTCAACGCAGCCAGG | ZBTB7C | ENSG00000184828 | 0.5391284930696428 | [834,651] | [697,1091] | 7 | hSpCas9 | negative selection | 4538656 | 48040877 | 48040899 | 18 | + | 27760321 | OCIAML2 | viability | GATCTCATAGACGTAGGGCTGG | ZBTB7C | ENSG00000184828 | 0.121857337384049 | [542,488] | [426,488] | 1 | hSpCas9 | negative selection | 4538657 | 48040339 | 48040361 | 18 | + | 27760321 | MV411 | viability | GAAAGAAGTCCGGGGCGAATGG | ZBTB7C | ENSG00000184828 | -0.5983945121403927 | [267,255] | [59,195] | -4 | hSpCas9 | negative selection | 4622116 | 48040411 | 48040433 | 18 | - | 27760321 | MV411 | viability | TCCATCGAATCTCTGCTAAGGG | ZBTB7C | ENSG00000184828 | 0.7944937825427019 | [211,177] | [135,351] | 6 | hSpCas9 | negative selection | 4622117 | 48040508 | 48040530 | 18 | + | 27760321 | MV411 | viability | ATAGGCCTTCTCTGTGAGATGG | ZBTB7C | ENSG00000184828 | -0.9131986396061025 | [321,244] | [50,169] | -6 | hSpCas9 | negative selection | 4622118 | 48040772 | 48040794 | 18 | - | 27760321 | MV411 | viability | GCACATCCTCAACGCAGCCAGG | ZBTB7C | ENSG00000184828 | 1.0003899956564055 | [834,651] | [1029,891] | 7 | hSpCas9 | negative selection | 4622119 | 48040877 | 48040899 | 18 | + | 27760321 | MV411 | viability | GATCTCATAGACGTAGGGCTGG | ZBTB7C | ENSG00000184828 | -0.3788776383829514 | [542,488] | [259,263] | -3 | hSpCas9 | negative selection | 4622120 | 48040339 | 48040361 | 18 | + | 27760321 | HL60 | viability | GAAAGAAGTCCGGGGCGAATGG | ZBTB7C | ENSG00000184828 | -0.05050197064990669 | [267,255] | [254,155] | 0 | hSpCas9 | negative selection | 4705579 | 48040411 | 48040433 | 18 | - | 27760321 | HL60 | viability | TCCATCGAATCTCTGCTAAGGG | ZBTB7C | ENSG00000184828 | 0.2388087075931381 | [211,177] | [161,213] | 3 | hSpCas9 | negative selection | 4705580 | 48040508 | 48040530 | 18 | + | 27760321 | HL60 | viability | ATAGGCCTTCTCTGTGAGATGG | ZBTB7C | ENSG00000184828 | -0.27434194707018655 | [321,244] | [155,225] | -3 | hSpCas9 | negative selection | 4705581 | 48040772 | 48040794 | 18 | - | 27760321 | HL60 | viability | GCACATCCTCAACGCAGCCAGG | ZBTB7C | ENSG00000184828 | 1.4336829159321272 | [834,651] | [1578,1682] | 9 | hSpCas9 | negative selection | 4705582 | 48040877 | 48040899 | 18 | + | 27760321 | HL60 | viability | GATCTCATAGACGTAGGGCTGG | ZBTB7C | ENSG00000184828 | -0.49270639161419405 | [542,488] | [224,377] | -5 | hSpCas9 | negative selection | 4705583 | 48040339 | 48040361 | 18 | + | 27760321 | HT1080 | viability | GAAAGAAGTCCGGGGCGAATGG | ZBTB7C | ENSG00000184828 | -0.1539389191822197 | [255,199] | [52,112] | 0 | hSpCas9 | negative selection | 4789042 | 48040411 | 48040433 | 18 | - | 27760321 | HT1080 | viability | TCCATCGAATCTCTGCTAAGGG | ZBTB7C | ENSG00000184828 | 0.5872717093752206 | [177,138] | [70,120] | 3 | hSpCas9 | negative selection | 4789043 | 48040508 | 48040530 | 18 | + | 27760321 | HT1080 | viability | ATAGGCCTTCTCTGTGAGATGG | ZBTB7C | ENSG00000184828 | 1.0180212253827103 | [244,190] | [193,155] | 5 | hSpCas9 | negative selection | 4789044 | 48040772 | 48040794 | 18 | - | 27760321 | HT1080 | viability | GCACATCCTCAACGCAGCCAGG | ZBTB7C | ENSG00000184828 | 0.6735862429348501 | [651,508] | [228,521] | 3 | hSpCas9 | negative selection | 4789045 | 48040877 | 48040899 | 18 | + | 27760321 | HT1080 | viability | GATCTCATAGACGTAGGGCTGG | ZBTB7C | ENSG00000184828 | -0.8432413429934928 | [488,381] | [79,114] | -4 | hSpCas9 | negative selection | 4789046 | 48040339 | 48040361 | 18 | + | 27760321 | HT29 | viability after 7 days | GAAAGAAGTCCGGGGCGAATGG | ZBTB7C | ENSG00000184828 | 0.1808663192662473 | [255,199] | [487,208,321] | 2 | hSpCas9 | negative selection | 4872505 | 48040411 | 48040433 | 18 | - | 27760321 | HT29 | viability after 7 days | TCCATCGAATCTCTGCTAAGGG | ZBTB7C | ENSG00000184828 | -0.10457287370283974 | [177,138] | [393,124,81] | -1 | hSpCas9 | negative selection | 4872506 | 48040508 | 48040530 | 18 | + | 27760321 | HT29 | viability after 7 days | ATAGGCCTTCTCTGTGAGATGG | ZBTB7C | ENSG00000184828 | 0.299002690924707 | [244,190] | [320,315,391] | 4 | hSpCas9 | negative selection | 4872507 | 48040772 | 48040794 | 18 | - | 27760321 | HT29 | viability after 7 days | GCACATCCTCAACGCAGCCAGG | ZBTB7C | ENSG00000184828 | 0.7416750450986623 | [651,508] | [1466,1329,984] | 9 | hSpCas9 | negative selection | 4872508 | 48040877 | 48040899 | 18 | + | 27760321 | HT29 | viability after 7 days | GATCTCATAGACGTAGGGCTGG | ZBTB7C | ENSG00000184828 | -0.32576257410513954 | [488,381] | [446,581,314] | -5 | hSpCas9 | negative selection | 4872509 | 48040339 | 48040361 | 18 | + | 27760321 | HT29 | viability after 25 days | GAAAGAAGTCCGGGGCGAATGG | ZBTB7C | ENSG00000184828 | -0.2806985918948991 | [255,199] | [300,76,264] | -3 | hSpCas9 | negative selection | 4955968 | 48040411 | 48040433 | 18 | - | 27760321 | HT29 | viability after 25 days | TCCATCGAATCTCTGCTAAGGG | ZBTB7C | ENSG00000184828 | 0.8414637169821384 | [177,138] | [273,398,300] | 8 | hSpCas9 | negative selection | 4955969 | 48040508 | 48040530 | 18 | + | 27760321 | HT29 | viability after 25 days | ATAGGCCTTCTCTGTGAGATGG | ZBTB7C | ENSG00000184828 | 0.012316653737627359 | [244,190] | [96,363,307] | 0 | hSpCas9 | negative selection | 4955970 | 48040772 | 48040794 | 18 | - | 27760321 | HT29 | viability after 25 days | GCACATCCTCAACGCAGCCAGG | ZBTB7C | ENSG00000184828 | 0.928901550285195 | [651,508] | [969,1629,1198] | 9 | hSpCas9 | negative selection | 4955971 | 48040877 | 48040899 | 18 | + | 27760321 | HT29 | viability after 25 days | GATCTCATAGACGTAGGGCTGG | ZBTB7C | ENSG00000184828 | -0.7522449806851246 | [488,381] | [170,408,315] | -6 | hSpCas9 | negative selection | 4955972 | 48040339 | 48040361 | 18 | + | 27760321 | HT29 | viability after 22 days | GAAAGAAGTCCGGGGCGAATGG | ZBTB7C | ENSG00000184828 | -0.013065635031133116 | [255,199] | [289,217,274] | 0 | hSpCas9 | negative selection | 5039431 | 48040411 | 48040433 | 18 | - | 27760321 | HT29 | viability after 22 days | TCCATCGAATCTCTGCTAAGGG | ZBTB7C | ENSG00000184828 | 0.5610567640599119 | [177,138] | [369,201,235] | 6 | hSpCas9 | negative selection | 5039432 | 48040508 | 48040530 | 18 | + | 27760321 | HT29 | viability after 22 days | ATAGGCCTTCTCTGTGAGATGG | ZBTB7C | ENSG00000184828 | -0.2282975633671075 | [244,190] | [191,235,217] | -2 | hSpCas9 | negative selection | 5039433 | 48040772 | 48040794 | 18 | - | 27760321 | HT29 | viability after 22 days | GCACATCCTCAACGCAGCCAGG | ZBTB7C | ENSG00000184828 | 1.0527618289369762 | [651,508] | [1143,1774,1262] | 9 | hSpCas9 | negative selection | 5039434 | 48040877 | 48040899 | 18 | + | 27760321 | HT29 | viability after 22 days | GATCTCATAGACGTAGGGCTGG | ZBTB7C | ENSG00000184828 | -0.4500874614689113 | [488,381] | [213,612,281] | -4 | hSpCas9 | negative selection | 5039435 | 48040339 | 48040361 | 18 | + | 27760321 | HT29 | viability after 19 days | GAAAGAAGTCCGGGGCGAATGG | ZBTB7C | ENSG00000184828 | -0.052410778481322806 | [255,199] | [353,186,224] | 0 | hSpCas9 | negative selection | 5122894 | 48040411 | 48040433 | 18 | - | 27760321 | HT29 | viability after 19 days | TCCATCGAATCTCTGCTAAGGG | ZBTB7C | ENSG00000184828 | 0.6767179385738713 | [177,138] | [263,461,145] | 7 | hSpCas9 | negative selection | 5122895 | 48040508 | 48040530 | 18 | + | 27760321 | HT29 | viability after 19 days | ATAGGCCTTCTCTGTGAGATGG | ZBTB7C | ENSG00000184828 | 0.5668116063029079 | [244,190] | [255,289,542] | 6 | hSpCas9 | negative selection | 5122896 | 48040772 | 48040794 | 18 | - | 27760321 | HT29 | viability after 19 days | GCACATCCTCAACGCAGCCAGG | ZBTB7C | ENSG00000184828 | 1.1112539429607242 | [651,508] | [1357,1906,1043] | 9 | hSpCas9 | negative selection | 5122897 | 48040877 | 48040899 | 18 | + | 27760321 | HT29 | viability after 19 days | GATCTCATAGACGTAGGGCTGG | ZBTB7C | ENSG00000184828 | -0.7385744841348603 | [488,381] | [418,297,194] | -5 | hSpCas9 | negative selection | 5122898 | 48040339 | 48040361 | 18 | + | 27760321 | HT29 | viability after 16 days | GAAAGAAGTCCGGGGCGAATGG | ZBTB7C | ENSG00000184828 | -0.3042667549730089 | [255,199] | [282,128,216] | -3 | hSpCas9 | negative selection | 5206357 | 48040411 | 48040433 | 18 | - | 27760321 | HT29 | viability after 16 days | TCCATCGAATCTCTGCTAAGGG | ZBTB7C | ENSG00000184828 | 0.3090854457274622 | [177,138] | [105,385,151] | 3 | hSpCas9 | negative selection | 5206358 | 48040508 | 48040530 | 18 | + | 27760321 | HT29 | viability after 16 days | ATAGGCCTTCTCTGTGAGATGG | ZBTB7C | ENSG00000184828 | 0.13805752753289213 | [244,190] | [194,273,328] | 1 | hSpCas9 | negative selection | 5206359 | 48040772 | 48040794 | 18 | - | 27760321 | HT29 | viability after 16 days | GCACATCCTCAACGCAGCCAGG | ZBTB7C | ENSG00000184828 | 1.1298785966379556 | [651,508] | [1506,1490,1271] | 9 | hSpCas9 | negative selection | 5206360 | 48040877 | 48040899 | 18 | + | 27760321 | HT29 | viability after 16 days | GATCTCATAGACGTAGGGCTGG | ZBTB7C | ENSG00000184828 | -0.47563768856329935 | [488,381] | [313,455,274] | -5 | hSpCas9 | negative selection | 5206361 | 48040339 | 48040361 | 18 | + | 27760321 | HT29 | viability after 13 days | GAAAGAAGTCCGGGGCGAATGG | ZBTB7C | ENSG00000184828 | -0.17008023183392906 | [255,199] | [269,230,205] | -2 | hSpCas9 | negative selection | 5289820 | 48040411 | 48040433 | 18 | - | 27760321 | HT29 | viability after 13 days | TCCATCGAATCTCTGCTAAGGG | ZBTB7C | ENSG00000184828 | 0.5598998961456042 | [177,138] | [186,348,276] | 7 | hSpCas9 | negative selection | 5289821 | 48040508 | 48040530 | 18 | + | 27760321 | HT29 | viability after 13 days | ATAGGCCTTCTCTGTGAGATGG | ZBTB7C | ENSG00000184828 | 0.0654982867725511 | [244,190] | [237,343,214] | 0 | hSpCas9 | negative selection | 5289822 | 48040772 | 48040794 | 18 | - | 27760321 | HT29 | viability after 13 days | GCACATCCTCAACGCAGCCAGG | ZBTB7C | ENSG00000184828 | 0.9141563741832369 | [651,508] | [1196,1217,1384] | 9 | hSpCas9 | negative selection | 5289823 | 48040877 | 48040899 | 18 | + | 27760321 | HT29 | viability after 13 days | GATCTCATAGACGTAGGGCTGG | ZBTB7C | ENSG00000184828 | -0.691682370834664 | [488,381] | [312,390,238] | -6 | hSpCas9 | negative selection | 5289824 | 48040339 | 48040361 | 18 | + | 27760321 | HT29 | viability after 10 days | GAAAGAAGTCCGGGGCGAATGG | ZBTB7C | ENSG00000184828 | -0.23697685894933362 | [255,199] | [295,143,280] | -3 | hSpCas9 | negative selection | 5373283 | 48040411 | 48040433 | 18 | - | 27760321 | HT29 | viability after 10 days | TCCATCGAATCTCTGCTAAGGG | ZBTB7C | ENSG00000184828 | 0.8543336360425157 | [177,138] | [362,328,379] | 9 | hSpCas9 | negative selection | 5373284 | 48040508 | 48040530 | 18 | + | 27760321 | HT29 | viability after 10 days | ATAGGCCTTCTCTGTGAGATGG | ZBTB7C | ENSG00000184828 | -0.037044119779542584 | [244,190] | [151,400,246] | 0 | hSpCas9 | negative selection | 5373285 | 48040772 | 48040794 | 18 | - | 27760321 | HT29 | viability after 10 days | GCACATCCTCAACGCAGCCAGG | ZBTB7C | ENSG00000184828 | 0.9884355853663523 | [651,508] | [1285,1789,1251] | 9 | hSpCas9 | negative selection | 5373286 | 48040877 | 48040899 | 18 | + | 27760321 | HT29 | viability after 10 days | GATCTCATAGACGTAGGGCTGG | ZBTB7C | ENSG00000184828 | -0.3125055546565397 | [488,381] | [265,563,485] | -4 | hSpCas9 | negative selection | 5373287 | 48040339 | 48040361 | 18 | + | 27760321 | MOLM13 | viability | GAAAGAAGTCCGGGGCGAATGG | ZBTB7C | ENSG00000184828 | -0.8004232897228528 | [267,255] | [37,124] | -5 | hSpCas9 | negative selection | 5456746 | 48040411 | 48040433 | 18 | - | 27760321 | MOLM13 | viability | TCCATCGAATCTCTGCTAAGGG | ZBTB7C | ENSG00000184828 | -0.41157280849172784 | [211,177] | [177,0] | -3 | hSpCas9 | negative selection | 5456747 | 48040508 | 48040530 | 18 | + | 27760321 | MOLM13 | viability | ATAGGCCTTCTCTGTGAGATGG | ZBTB7C | ENSG00000184828 | -0.7047715044470364 | [321,244] | [152,49] | -4 | hSpCas9 | negative selection | 5456748 | 48040772 | 48040794 | 18 | - | 27760321 | MOLM13 | viability | GCACATCCTCAACGCAGCCAGG | ZBTB7C | ENSG00000184828 | 1.2414377174433806 | [834,651] | [1024,950] | 8 | hSpCas9 | negative selection | 5456749 | 48040877 | 48040899 | 18 | + | 27760321 | MOLM13 | viability | GATCTCATAGACGTAGGGCTGG | ZBTB7C | ENSG00000184828 | 0.8040478330180622 | [542,488] | [281,699] | 5 | hSpCas9 | negative selection | 5456750 | 48136665 | 48136688 | 18 | + | 27661255 | K562 | viability | GGCGTGGGCCGGCGGCAATGGGG | ZBTB7C | ENSG00000184828 | 0.15222576090430612 | [521,602] | [571,434] | 5 | dCas9-KRAB | negative selection | 5523629 | 48136890 | 48136913 | 18 | + | 27661255 | K562 | viability | GCTCTCCCGGCCGCCCGGAAGGG | ZBTB7C | ENSG00000184828 | -0.08317128758948567 | [149,182] | [116,131] | -3 | dCas9-KRAB | negative selection | 5523630 | 48409340 | 48409363 | 18 | + | 27661255 | K562 | viability | GCGCCGCTGTCAGAGTCTCGTGG | ZBTB7C | ENSG00000184828 | 0.2502464215135398 | [161,148] | [161,135] | 8 | dCas9-KRAB | negative selection | 5523631 | 48136620 | 48136643 | 18 | - | 27661255 | K562 | viability | GGCCAGCCGAAGGAACGTAAGGG | ZBTB7C | ENSG00000184828 | 0.0462673536892767 | [396,433] | [393,297] | 1 | dCas9-KRAB | negative selection | 5523632 | 48408947 | 48408970 | 18 | - | 27661255 | K562 | viability | GTGCGGCAGCCATGCAACGGAGG | ZBTB7C | ENSG00000184828 | 0.16933627614268232 | [990,1036] | [928,893] | 6 | dCas9-KRAB | negative selection | 5523633 | 48408964 | 48408987 | 18 | - | 27661255 | K562 | viability | GGCTATTCAGGGGCTCCGTGCGG | ZBTB7C | ENSG00000184828 | 0.026995679629897136 | [772,772] | [721,549] | 0 | dCas9-KRAB | negative selection | 5523634 | 48409299 | 48409322 | 18 | - | 27661255 | K562 | viability | GCGCAGGGACCGGCGGACACCGG | ZBTB7C | ENSG00000184828 | -0.012104011435515927 | [996,965] | [812,747] | 0 | dCas9-KRAB | negative selection | 5523635 | 48029818 | 48029841 | 18 | + | 27260156 | BXPC3 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.014556148374083916 | [474] | [486,473,413,647] | 0 | hSpCas9 | negative selection | 5580999 | 48040115 | 48040138 | 18 | + | 27260156 | BXPC3 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.30968519477624235 | [834] | [1013,1041,1140,1141] | 6 | hSpCas9 | negative selection | 5581000 | 48040735 | 48040758 | 18 | - | 27260156 | BXPC3 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.15247226029853667 | [965] | [1037,1080,1102,1292] | 3 | hSpCas9 | negative selection | 5581001 | 48029362 | 48029385 | 18 | + | 27260156 | BXPC3 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.45293314583447397 | [468] | [626,685,622,757] | 8 | hSpCas9 | negative selection | 5645246 | 48040793 | 48040816 | 18 | + | 27260156 | BXPC3 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.8440344946059539 | [85] | [151,175,142,174] | 9 | hSpCas9 | negative selection | 5645247 | 48029754 | 48029777 | 18 | + | 27260156 | BXPC3 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.44825320486888215 | [766] | [511,479,638,751] | -7 | hSpCas9 | negative selection | 5645248 | 48029818 | 48029841 | 18 | + | 27260156 | A673 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.07515630990192299 | [474] | [419,595,599,531] | -2 | hSpCas9 | negative selection | 5702250 | 48040115 | 48040138 | 18 | + | 27260156 | A673 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.2672101833224535 | [834] | [1332,1043,1264,1199] | 6 | hSpCas9 | negative selection | 5702251 | 48040735 | 48040758 | 18 | - | 27260156 | A673 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.15051873072573407 | [965] | [1474,1080,1153,1475] | 3 | hSpCas9 | negative selection | 5702252 | 48029362 | 48029385 | 18 | + | 27260156 | A673 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.3463906714552251 | [468] | [863,600,681,736] | 7 | hSpCas9 | negative selection | 5766497 | 48040793 | 48040816 | 18 | + | 27260156 | A673 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.2295907837392459 | [85] | [143,111,168,57] | 5 | hSpCas9 | negative selection | 5766498 | 48029754 | 48029777 | 18 | + | 27260156 | A673 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.3772143255371166 | [766] | [642,730,791,656] | -7 | hSpCas9 | negative selection | 5766499 | 48029818 | 48029841 | 18 | + | 27260156 | A375 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.03818871162367032 | [474] | [500,519,640,498] | 0 | hSpCas9 | negative selection | 5823501 | 48040115 | 48040138 | 18 | + | 27260156 | A375 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.5879377555544619 | [834] | [1425,1654,1401,1407] | 8 | hSpCas9 | negative selection | 5823502 | 48040735 | 48040758 | 18 | - | 27260156 | A375 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.42321250086265194 | [965] | [1579,1762,1381,1372] | 6 | hSpCas9 | negative selection | 5823503 | 48029362 | 48029385 | 18 | + | 27260156 | A375 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.37839607406727443 | [468] | [875,775,707,518] | 5 | hSpCas9 | negative selection | 5887748 | 48040793 | 48040816 | 18 | + | 27260156 | A375 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.3595887672944933 | [85] | [92,96,169,147] | 5 | hSpCas9 | negative selection | 5887749 | 48029754 | 48029777 | 18 | + | 27260156 | A375 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.30895512126231317 | [766] | [819,929,526,650] | -4 | hSpCas9 | negative selection | 5887750 | 48029818 | 48029841 | 18 | + | 27260156 | COLO741 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.14194777106268497 | [474] | [519,528,593] | -3 | hSpCas9 | negative selection | 5944752 | 48040115 | 48040138 | 18 | + | 27260156 | COLO741 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.5205763177750932 | [834] | [1702,1601,1313] | 9 | hSpCas9 | negative selection | 5944753 | 48040735 | 48040758 | 18 | - | 27260156 | COLO741 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.12643926597081334 | [965] | [1311,1292,1424] | 2 | hSpCas9 | negative selection | 5944754 | 48029362 | 48029385 | 18 | + | 27260156 | COLO741 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.281637775673567 | [468] | [738,890,566] | 6 | hSpCas9 | negative selection | 6008999 | 48040793 | 48040816 | 18 | + | 27260156 | COLO741 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.5614010241368139 | [85] | [121,145,210] | 9 | hSpCas9 | negative selection | 6009000 | 48029754 | 48029777 | 18 | + | 27260156 | COLO741 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.4397425055595534 | [766] | [714,792,661] | -7 | hSpCas9 | negative selection | 6009001 | 48029818 | 48029841 | 18 | + | 27260156 | CAL120 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.027253993546105915 | [474] | [344,417,934] | 0 | hSpCas9 | negative selection | 6066003 | 48040115 | 48040138 | 18 | + | 27260156 | CAL120 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.6411932908016079 | [834] | [1882,1483,1534] | 8 | hSpCas9 | negative selection | 6066004 | 48040735 | 48040758 | 18 | - | 27260156 | CAL120 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.3259106795202149 | [965] | [1782,1148,1626] | 5 | hSpCas9 | negative selection | 6066005 | 48029362 | 48029385 | 18 | + | 27260156 | CAL120 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.3337364410415786 | [468] | [894,697,638] | 5 | hSpCas9 | negative selection | 6130250 | 48040793 | 48040816 | 18 | + | 27260156 | CAL120 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.11723539544351746 | [85] | [171,146,38] | 1 | hSpCas9 | negative selection | 6130251 | 48029754 | 48029777 | 18 | + | 27260156 | CAL120 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.6716154612284027 | [766] | [828,574,430] | -7 | hSpCas9 | negative selection | 6130252 | 48029818 | 48029841 | 18 | + | 27260156 | CADOES1 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.21473960648625492 | [474] | [418,362,374,364] | -4 | hSpCas9 | negative selection | 6187254 | 48040115 | 48040138 | 18 | + | 27260156 | CADOES1 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.3712733991742255 | [834] | [1072,841,1137,962] | 6 | hSpCas9 | negative selection | 6187255 | 48040735 | 48040758 | 18 | - | 27260156 | CADOES1 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.26805359626276104 | [965] | [1202,971,916,1240] | 4 | hSpCas9 | negative selection | 6187256 | 48029362 | 48029385 | 18 | + | 27260156 | CADOES1 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.5089198007780598 | [468] | [542,768,558,611] | 8 | hSpCas9 | negative selection | 6251501 | 48040793 | 48040816 | 18 | + | 27260156 | CADOES1 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.21477859171820146 | [85] | [133,75,97,61] | 3 | hSpCas9 | negative selection | 6251502 | 48029754 | 48029777 | 18 | + | 27260156 | CADOES1 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.8233415364428194 | [766] | [357,379,435,439] | -8 | hSpCas9 | negative selection | 6251503 | 48029818 | 48029841 | 18 | + | 27260156 | EWS502 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.17439382342641674 | [474] | [753,393,550,552] | 3 | hSpCas9 | negative selection | 6308505 | 48040115 | 48040138 | 18 | + | 27260156 | EWS502 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.5081370959193706 | [834] | [1073,1066,1552,1374] | 8 | hSpCas9 | negative selection | 6308506 | 48040735 | 48040758 | 18 | - | 27260156 | EWS502 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.21887380479125196 | [965] | [1262,1246,1179,1046] | 4 | hSpCas9 | negative selection | 6308507 | 48029362 | 48029385 | 18 | + | 27260156 | EWS502 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.5134711054730736 | [468] | [664,691,607,885] | 8 | hSpCas9 | negative selection | 6372752 | 48040793 | 48040816 | 18 | + | 27260156 | EWS502 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | -0.36862001655266097 | [85] | [71,82,39,86] | -6 | hSpCas9 | negative selection | 6372753 | 48029754 | 48029777 | 18 | + | 27260156 | EWS502 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.4949892232208886 | [766] | [771,457,528,520] | -7 | hSpCas9 | negative selection | 6372754 | 48029818 | 48029841 | 18 | + | 27260156 | EW8 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.250256539237389 | [474] | [323,395,288,290] | -5 | hSpCas9 | negative selection | 6429756 | 48040115 | 48040138 | 18 | + | 27260156 | EW8 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.5293971896781183 | [834] | [1116,927,684,1237] | 8 | hSpCas9 | negative selection | 6429757 | 48040735 | 48040758 | 18 | - | 27260156 | EW8 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.5165496520611979 | [965] | [1485,1011,1058,969] | 8 | hSpCas9 | negative selection | 6429758 | 48029362 | 48029385 | 18 | + | 27260156 | EW8 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.4115073408188452 | [468] | [662,476,452,453] | 7 | hSpCas9 | negative selection | 6494003 | 48040793 | 48040816 | 18 | + | 27260156 | EW8 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.5082171788108969 | [85] | [56,100,113,116] | 8 | hSpCas9 | negative selection | 6494004 | 48029754 | 48029777 | 18 | + | 27260156 | EW8 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.15541894355747254 | [766] | [546,528,601,543] | -3 | hSpCas9 | negative selection | 6494005 | 48029818 | 48029841 | 18 | + | 27260156 | CORL105 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.305942535515713 | [474] | [447,507,548,308] | -5 | hSpCas9 | negative selection | 6551007 | 48040115 | 48040138 | 18 | + | 27260156 | CORL105 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.17971602901253714 | [834] | [1184,1067,1150,1034] | 3 | hSpCas9 | negative selection | 6551008 | 48040735 | 48040758 | 18 | - | 27260156 | CORL105 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.40050029273810206 | [965] | [1464,1523,1343,1611] | 7 | hSpCas9 | negative selection | 6551009 | 48029362 | 48029385 | 18 | + | 27260156 | CORL105 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.4268954364670073 | [468] | [817,524,690,916] | 7 | hSpCas9 | negative selection | 6615254 | 48040793 | 48040816 | 18 | + | 27260156 | CORL105 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.32347880105436166 | [85] | [194,106,101,98] | 6 | hSpCas9 | negative selection | 6615255 | 48029754 | 48029777 | 18 | + | 27260156 | CORL105 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.6686476150003005 | [766] | [700,426,691,466] | -8 | hSpCas9 | negative selection | 6615256 | 48029818 | 48029841 | 18 | + | 27260156 | HS294T | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.10200580255113958 | [474] | [163,206,245,168] | 1 | hSpCas9 | negative selection | 6672258 | 48040115 | 48040138 | 18 | + | 27260156 | HS294T | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.43141550919902294 | [834] | [380,347,500,534] | 6 | hSpCas9 | negative selection | 6672259 | 48040735 | 48040758 | 18 | - | 27260156 | HS294T | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.235599976731385 | [965] | [441,368,487,464] | 3 | hSpCas9 | negative selection | 6672260 | 48029362 | 48029385 | 18 | + | 27260156 | HS294T | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.2978079023899433 | [468] | [248,175,181,294] | 4 | hSpCas9 | negative selection | 6736505 | 48040793 | 48040816 | 18 | + | 27260156 | HS294T | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | -0.14382582724155357 | [85] | [20,24,31,45] | -2 | hSpCas9 | negative selection | 6736506 | 48029754 | 48029777 | 18 | + | 27260156 | HS294T | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.3031956926820343 | [766] | [181,328,197,256] | -4 | hSpCas9 | negative selection | 6736507 | 48029818 | 48029841 | 18 | + | 27260156 | HCC44 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.043603157330313405 | [474] | [705,470,545,512] | 0 | hSpCas9 | negative selection | 6793509 | 48040115 | 48040138 | 18 | + | 27260156 | HCC44 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.4813697207208062 | [834] | [1383,925,1380,1633] | 7 | hSpCas9 | negative selection | 6793510 | 48040735 | 48040758 | 18 | - | 27260156 | HCC44 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.4174324725864056 | [965] | [1598,1184,1966,1220] | 7 | hSpCas9 | negative selection | 6793511 | 48029362 | 48029385 | 18 | + | 27260156 | HCC44 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.2450712584235617 | [468] | [676,460,923,529] | 4 | hSpCas9 | negative selection | 6857756 | 48040793 | 48040816 | 18 | + | 27260156 | HCC44 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.5819427428987849 | [85] | [141,130,138,168] | 8 | hSpCas9 | negative selection | 6857757 | 48029754 | 48029777 | 18 | + | 27260156 | HCC44 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.20315325344089497 | [766] | [1048,528,780,713] | -3 | hSpCas9 | negative selection | 6857758 | 48029818 | 48029841 | 18 | + | 27260156 | G402 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.13883857734179128 | [474] | [678,559,539,356] | -2 | hSpCas9 | negative selection | 6914760 | 48040115 | 48040138 | 18 | + | 27260156 | G402 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.4778616244125552 | [834] | [1763,1675,1022,1278] | 6 | hSpCas9 | negative selection | 6914761 | 48040735 | 48040758 | 18 | - | 27260156 | G402 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.543186541306101 | [965] | [2202,1946,1541,1276] | 6 | hSpCas9 | negative selection | 6914762 | 48029362 | 48029385 | 18 | + | 27260156 | G402 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.6795005177859367 | [468] | [793,1012,830,1007] | 8 | hSpCas9 | negative selection | 6979007 | 48040793 | 48040816 | 18 | + | 27260156 | G402 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.21427560387913225 | [85] | [153,89,95,147] | 2 | hSpCas9 | negative selection | 6979008 | 48029754 | 48029777 | 18 | + | 27260156 | G402 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.05103755467262694 | [766] | [1477,593,731,1114] | 0 | hSpCas9 | negative selection | 6979009 | 48029818 | 48029841 | 18 | + | 27260156 | L33 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.5017700806761773 | [474] | [360,151,175,328] | -8 | hSpCas9 | negative selection | 7036011 | 48040115 | 48040138 | 18 | + | 27260156 | L33 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.1414751906935353 | [834] | [870,420,587,851] | 3 | hSpCas9 | negative selection | 7036012 | 48040735 | 48040758 | 18 | - | 27260156 | L33 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.21249088297095042 | [965] | [993,522,622,1216] | 4 | hSpCas9 | negative selection | 7036013 | 48029362 | 48029385 | 18 | + | 27260156 | L33 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.11346931404116466 | [468] | [435,173,421,499] | 2 | hSpCas9 | negative selection | 7100258 | 48040793 | 48040816 | 18 | + | 27260156 | L33 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.08882297381721971 | [85] | [91,55,47,60] | 2 | hSpCas9 | negative selection | 7100259 | 48029754 | 48029777 | 18 | + | 27260156 | L33 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.48101667571392137 | [766] | [531,195,350,628] | -8 | hSpCas9 | negative selection | 7100260 | 48029818 | 48029841 | 18 | + | 27260156 | K562 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.44296285614855374 | [474] | [374,272,308,287] | -5 | hSpCas9 | negative selection | 7157262 | 48040115 | 48040138 | 18 | + | 27260156 | K562 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.6966498659930688 | [834] | [1428,1569,553,1274] | 8 | hSpCas9 | negative selection | 7157263 | 48040735 | 48040758 | 18 | - | 27260156 | K562 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.15688339688059894 | [965] | [1327,897,991,662] | 2 | hSpCas9 | negative selection | 7157264 | 48029362 | 48029385 | 18 | + | 27260156 | K562 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.5067817423102633 | [468] | [779,284,834,475] | 6 | hSpCas9 | negative selection | 7221509 | 48040793 | 48040816 | 18 | + | 27260156 | K562 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.9368692099322931 | [85] | [343,163,22,77] | 9 | hSpCas9 | negative selection | 7221510 | 48029754 | 48029777 | 18 | + | 27260156 | K562 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.5900648238095437 | [766] | [304,682,490,340] | -6 | hSpCas9 | negative selection | 7221511 | 48029818 | 48029841 | 18 | + | 27260156 | HT29 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.2182165131321513 | [474] | [460,553,543,432] | -4 | hSpCas9 | negative selection | 7278513 | 48040115 | 48040138 | 18 | + | 27260156 | HT29 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.47349598813689375 | [834] | [1491,1562,1400,1214] | 8 | hSpCas9 | negative selection | 7278514 | 48040735 | 48040758 | 18 | - | 27260156 | HT29 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.23046062392216027 | [965] | [1338,1483,1594,1120] | 4 | hSpCas9 | negative selection | 7278515 | 48029362 | 48029385 | 18 | + | 27260156 | HT29 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.2948249164884151 | [468] | [659,753,903,500] | 6 | hSpCas9 | negative selection | 7342760 | 48040793 | 48040816 | 18 | + | 27260156 | HT29 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.3708475672052005 | [85] | [102,154,136,142] | 7 | hSpCas9 | negative selection | 7342761 | 48029754 | 48029777 | 18 | + | 27260156 | HT29 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.5883183919879015 | [766] | [578,629,700,569] | -7 | hSpCas9 | negative selection | 7342762 | 48029818 | 48029841 | 18 | + | 27260156 | MHHES1 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.08054428370612382 | [474] | [580,436,692,342] | -1 | hSpCas9 | negative selection | 7399764 | 48040115 | 48040138 | 18 | + | 27260156 | MHHES1 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.2485187291112968 | [834] | [1298,1149,1124,936] | 4 | hSpCas9 | negative selection | 7399765 | 48040735 | 48040758 | 18 | - | 27260156 | MHHES1 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.23546182185540676 | [965] | [1773,1540,1272,723] | 4 | hSpCas9 | negative selection | 7399766 | 48029362 | 48029385 | 18 | + | 27260156 | MHHES1 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.47668362751067184 | [468] | [753,729,540,866] | 8 | hSpCas9 | negative selection | 7464011 | 48040793 | 48040816 | 18 | + | 27260156 | MHHES1 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.5691523635945326 | [85] | [157,230,76,120] | 8 | hSpCas9 | negative selection | 7464012 | 48029754 | 48029777 | 18 | + | 27260156 | MHHES1 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.14529668467831935 | [766] | [983,726,762,675] | -3 | hSpCas9 | negative selection | 7464013 | 48029818 | 48029841 | 18 | + | 27260156 | MEWO | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.10168156505742469 | [474] | [415,401,600] | 2 | hSpCas9 | negative selection | 7521015 | 48040115 | 48040138 | 18 | + | 27260156 | MEWO | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.2128825331814147 | [834] | [1021,823,892] | 4 | hSpCas9 | negative selection | 7521016 | 48040735 | 48040758 | 18 | - | 27260156 | MEWO | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.10983892271812845 | [965] | [1043,942,951] | 2 | hSpCas9 | negative selection | 7521017 | 48029362 | 48029385 | 18 | + | 27260156 | MEWO | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.30992554353022816 | [468] | [847,456,385] | 6 | hSpCas9 | negative selection | 7585262 | 48040793 | 48040816 | 18 | + | 27260156 | MEWO | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.4531170596075973 | [85] | [189,86,68] | 8 | hSpCas9 | negative selection | 7585263 | 48029754 | 48029777 | 18 | + | 27260156 | MEWO | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.03756463567294699 | [766] | [919,500,719] | -1 | hSpCas9 | negative selection | 7585264 | 48029818 | 48029841 | 18 | + | 27260156 | LNCAPCLONEFGC | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.24201274202342946 | [474] | [434,244,440,351] | -4 | hSpCas9 | negative selection | 7642266 | 48040115 | 48040138 | 18 | + | 27260156 | LNCAPCLONEFGC | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.7142199362149325 | [834] | [1341,995,1556,1128] | 9 | hSpCas9 | negative selection | 7642267 | 48040735 | 48040758 | 18 | - | 27260156 | LNCAPCLONEFGC | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.44406260740871284 | [965] | [1252,990,1439,1125] | 7 | hSpCas9 | negative selection | 7642268 | 48029362 | 48029385 | 18 | + | 27260156 | LNCAPCLONEFGC | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.6696158692984475 | [468] | [585,707,774,647] | 9 | hSpCas9 | negative selection | 7706513 | 48040793 | 48040816 | 18 | + | 27260156 | LNCAPCLONEFGC | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.4319518450419819 | [85] | [102,83,126,110] | 6 | hSpCas9 | negative selection | 7706514 | 48029754 | 48029777 | 18 | + | 27260156 | LNCAPCLONEFGC | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.7833604335860594 | [766] | [366,334,499,431] | -8 | hSpCas9 | negative selection | 7706515 | 48029818 | 48029841 | 18 | + | 27260156 | PANC0327 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.1891926311523165 | [474] | [306,224,518,442] | -3 | hSpCas9 | negative selection | 7763517 | 48040115 | 48040138 | 18 | + | 27260156 | PANC0327 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.5333027292864944 | [834] | [1256,1001,1118,939] | 7 | hSpCas9 | negative selection | 7763518 | 48040735 | 48040758 | 18 | - | 27260156 | PANC0327 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.6238035645374123 | [965] | [1695,938,1408,1324] | 8 | hSpCas9 | negative selection | 7763519 | 48029362 | 48029385 | 18 | + | 27260156 | PANC0327 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.769199714052072 | [468] | [715,628,761,743] | 9 | hSpCas9 | negative selection | 7827764 | 48040793 | 48040816 | 18 | + | 27260156 | PANC0327 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | -0.019633876774534986 | [85] | [144,44,43,76] | 0 | hSpCas9 | negative selection | 7827765 | 48029754 | 48029777 | 18 | + | 27260156 | PANC0327 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.058077034273645745 | [766] | [835,634,680,704] | 0 | hSpCas9 | negative selection | 7827766 | 48029818 | 48029841 | 18 | + | 27260156 | NCIH2009 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.014865712324469227 | [474] | [717,684,577] | 0 | hSpCas9 | negative selection | 7884768 | 48040115 | 48040138 | 18 | + | 27260156 | NCIH2009 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.47710674376880735 | [834] | [2031,1709,1205] | 6 | hSpCas9 | negative selection | 7884769 | 48040735 | 48040758 | 18 | - | 27260156 | NCIH2009 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.6547523636432506 | [965] | [2590,2234,1634] | 8 | hSpCas9 | negative selection | 7884770 | 48029362 | 48029385 | 18 | + | 27260156 | NCIH2009 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.5721507988842357 | [468] | [1304,993,686] | 7 | hSpCas9 | negative selection | 7949015 | 48040793 | 48040816 | 18 | + | 27260156 | NCIH2009 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.21514838761955168 | [85] | [164,152,104] | 3 | hSpCas9 | negative selection | 7949016 | 48029754 | 48029777 | 18 | + | 27260156 | NCIH2009 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.0044311814980755315 | [766] | [1253,1116,867] | 0 | hSpCas9 | negative selection | 7949017 | 48029818 | 48029841 | 18 | + | 27260156 | NCIH1373 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.4982194944085617 | [474] | [1280,265,784,212] | 5 | hSpCas9 | negative selection | 8006019 | 48040115 | 48040138 | 18 | + | 27260156 | NCIH1373 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.6346286014426362 | [834] | [1008,1715,1595,361] | 6 | hSpCas9 | negative selection | 8006020 | 48040735 | 48040758 | 18 | - | 27260156 | NCIH1373 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 1.045407005208986 | [965] | [1637,1445,3310,661] | 9 | hSpCas9 | negative selection | 8006021 | 48029362 | 48029385 | 18 | + | 27260156 | NCIH1373 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.7065156552091864 | [468] | [953,702,834,255] | 7 | hSpCas9 | negative selection | 8070266 | 48040793 | 48040816 | 18 | + | 27260156 | NCIH1373 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | -0.1697408027478251 | [85] | [18,54,129,34] | -2 | hSpCas9 | negative selection | 8070267 | 48029754 | 48029777 | 18 | + | 27260156 | NCIH1373 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.3214360835046576 | [766] | [872,916,561,100] | -3 | hSpCas9 | negative selection | 8070268 | 48029818 | 48029841 | 18 | + | 27260156 | PATU8902 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.19751813455380632 | [474] | [599,639,665,345] | -2 | hSpCas9 | negative selection | 8127270 | 48040115 | 48040138 | 18 | + | 27260156 | PATU8902 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.5029857189951935 | [834] | [1892,1475,1528,1715] | 5 | hSpCas9 | negative selection | 8127271 | 48040735 | 48040758 | 18 | - | 27260156 | PATU8902 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.504068920795993 | [965] | [1637,1892,2137,1888] | 5 | hSpCas9 | negative selection | 8127272 | 48029362 | 48029385 | 18 | + | 27260156 | PATU8902 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.6510266845989432 | [468] | [1077,816,438,2031] | 7 | hSpCas9 | negative selection | 8191517 | 48040793 | 48040816 | 18 | + | 27260156 | PATU8902 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | -1.5201166721764685 | [85] | [13,28,42,85] | -8 | hSpCas9 | negative selection | 8191518 | 48029754 | 48029777 | 18 | + | 27260156 | PATU8902 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.771932111373467 | [766] | [504,888,571,536] | -6 | hSpCas9 | negative selection | 8191519 | 48029818 | 48029841 | 18 | + | 27260156 | PANC1 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.17180098528169366 | [474] | [317,365,446,320] | -3 | hSpCas9 | negative selection | 8248521 | 48040115 | 48040138 | 18 | + | 27260156 | PANC1 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.4612827956750364 | [834] | [1181,1088,833,863] | 7 | hSpCas9 | negative selection | 8248522 | 48040735 | 48040758 | 18 | - | 27260156 | PANC1 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.39770748305462145 | [965] | [975,1466,1056,955] | 6 | hSpCas9 | negative selection | 8248523 | 48029362 | 48029385 | 18 | + | 27260156 | PANC1 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.3803485458734127 | [468] | [551,453,644,437] | 6 | hSpCas9 | negative selection | 8312768 | 48040793 | 48040816 | 18 | + | 27260156 | PANC1 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | -0.10888440508852604 | [85] | [118,74,45,37] | -2 | hSpCas9 | negative selection | 8312769 | 48029754 | 48029777 | 18 | + | 27260156 | PANC1 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.41477543752808044 | [766] | [468,475,562,462] | -6 | hSpCas9 | negative selection | 8312770 | 48029818 | 48029841 | 18 | + | 27260156 | PANC0813 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.3015573001323189 | [474] | [717,796,864,389] | 5 | hSpCas9 | negative selection | 8369772 | 48040115 | 48040138 | 18 | + | 27260156 | PANC0813 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.39182332019534416 | [834] | [1096,1613,1267,1155] | 6 | hSpCas9 | negative selection | 8369773 | 48040735 | 48040758 | 18 | - | 27260156 | PANC0813 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.460724908355405 | [965] | [1461,1640,1558,1571] | 7 | hSpCas9 | negative selection | 8369774 | 48029362 | 48029385 | 18 | + | 27260156 | PANC0813 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.45508099450274847 | [468] | [701,682,783,840] | 7 | hSpCas9 | negative selection | 8434019 | 48040793 | 48040816 | 18 | + | 27260156 | PANC0813 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.1789353853154374 | [85] | [95,149,121,88] | 3 | hSpCas9 | negative selection | 8434020 | 48029754 | 48029777 | 18 | + | 27260156 | PANC0813 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.0797458400937836 | [766] | [973,1162,486,796] | -1 | hSpCas9 | negative selection | 8434021 | 48029818 | 48029841 | 18 | + | 27260156 | RDES | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.02223094388231344 | [474] | [524,433,653,537] | 0 | hSpCas9 | negative selection | 8491023 | 48040115 | 48040138 | 18 | + | 27260156 | RDES | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.3889640733646903 | [834] | [1094,1088,1388,1512] | 6 | hSpCas9 | negative selection | 8491024 | 48040735 | 48040758 | 18 | - | 27260156 | RDES | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.32620229588301997 | [965] | [1052,1419,1498,1675] | 5 | hSpCas9 | negative selection | 8491025 | 48029362 | 48029385 | 18 | + | 27260156 | RDES | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.6857478454073263 | [468] | [772,807,993,903] | 9 | hSpCas9 | negative selection | 8555270 | 48040793 | 48040816 | 18 | + | 27260156 | RDES | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | -0.05861468331805275 | [85] | [53,78,136,123] | -1 | hSpCas9 | negative selection | 8555271 | 48029754 | 48029777 | 18 | + | 27260156 | RDES | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.5932257565306834 | [766] | [567,552,612,593] | -7 | hSpCas9 | negative selection | 8555272 | 48029818 | 48029841 | 18 | + | 27260156 | PC3 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.5561799802568717 | [474] | [204,322,549,317] | -8 | hSpCas9 | negative selection | 8612274 | 48040115 | 48040138 | 18 | + | 27260156 | PC3 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.27037505115901117 | [834] | [792,947,1382,1013] | 6 | hSpCas9 | negative selection | 8612275 | 48040735 | 48040758 | 18 | - | 27260156 | PC3 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.30438463410729266 | [965] | [797,1043,1889,1361] | 6 | hSpCas9 | negative selection | 8612276 | 48029362 | 48029385 | 18 | + | 27260156 | PC3 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.3078837332590844 | [468] | [399,474,1025,612] | 6 | hSpCas9 | negative selection | 8676521 | 48040793 | 48040816 | 18 | + | 27260156 | PC3 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | -0.11071141870284906 | [85] | [53,96,121,61] | -2 | hSpCas9 | negative selection | 8676522 | 48029754 | 48029777 | 18 | + | 27260156 | PC3 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.26191546132132076 | [766] | [362,561,1176,730] | -5 | hSpCas9 | negative selection | 8676523 | 48029818 | 48029841 | 18 | + | 27260156 | PATU8988T | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.0484484287491723 | [474] | [263,608,629,399] | 0 | hSpCas9 | negative selection | 8733525 | 48040115 | 48040138 | 18 | + | 27260156 | PATU8988T | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.3242771025633827 | [834] | [895,885,900,1376] | 5 | hSpCas9 | negative selection | 8733526 | 48040735 | 48040758 | 18 | - | 27260156 | PATU8988T | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.3281398013101655 | [965] | [989,1204,1107,1406] | 5 | hSpCas9 | negative selection | 8733527 | 48029362 | 48029385 | 18 | + | 27260156 | PATU8988T | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.6192782787968244 | [468] | [486,1151,679,491] | 8 | hSpCas9 | negative selection | 8797772 | 48040793 | 48040816 | 18 | + | 27260156 | PATU8988T | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 1.011045023436718 | [85] | [60,175,13,443] | 9 | hSpCas9 | negative selection | 8797773 | 48029754 | 48029777 | 18 | + | 27260156 | PATU8988T | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.21236107666914567 | [766] | [555,532,643,830] | -4 | hSpCas9 | negative selection | 8797774 | 48029818 | 48029841 | 18 | + | 27260156 | T47D | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.07669399606332603 | [474] | [555,418,540,593] | -2 | hSpCas9 | negative selection | 8854776 | 48040115 | 48040138 | 18 | + | 27260156 | T47D | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.2916871788006611 | [834] | [1341,1105,1080,1244] | 6 | hSpCas9 | negative selection | 8854777 | 48040735 | 48040758 | 18 | - | 27260156 | T47D | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.204245402084835 | [965] | [1378,1369,1199,1229] | 4 | hSpCas9 | negative selection | 8854778 | 48029362 | 48029385 | 18 | + | 27260156 | T47D | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.47610120814786816 | [468] | [834,677,793,738] | 8 | hSpCas9 | negative selection | 8919023 | 48040793 | 48040816 | 18 | + | 27260156 | T47D | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.3568599834024022 | [85] | [120,142,139,106] | 7 | hSpCas9 | negative selection | 8919024 | 48029754 | 48029777 | 18 | + | 27260156 | T47D | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.4430483675065369 | [766] | [662,600,689,679] | -7 | hSpCas9 | negative selection | 8919025 | 48029818 | 48029841 | 18 | + | 27260156 | SU8686 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.03059836299330592 | [474] | [364,499,533,543] | 0 | hSpCas9 | negative selection | 8976027 | 48040115 | 48040138 | 18 | + | 27260156 | SU8686 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.284423283691141 | [834] | [912,1129,1031,933] | 5 | hSpCas9 | negative selection | 8976028 | 48040735 | 48040758 | 18 | - | 27260156 | SU8686 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.24954616833918797 | [965] | [1110,1105,1197,1139] | 4 | hSpCas9 | negative selection | 8976029 | 48029362 | 48029385 | 18 | + | 27260156 | SU8686 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.3845248074734341 | [468] | [592,612,538,690] | 6 | hSpCas9 | negative selection | 9040274 | 48040793 | 48040816 | 18 | + | 27260156 | SU8686 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.49859252839668855 | [85] | [85,137,101,162] | 8 | hSpCas9 | negative selection | 9040275 | 48029754 | 48029777 | 18 | + | 27260156 | SU8686 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.09002375025691212 | [766] | [943,638,848,806] | 1 | hSpCas9 | negative selection | 9040276 | 48029818 | 48029841 | 18 | + | 27260156 | SKES1 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | 0.0877640374986037 | [474] | [598,426,523,466] | 2 | hSpCas9 | negative selection | 9097278 | 48040115 | 48040138 | 18 | + | 27260156 | SKES1 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.3519963412168544 | [834] | [1298,1015,939,1019] | 7 | hSpCas9 | negative selection | 9097279 | 48040735 | 48040758 | 18 | - | 27260156 | SKES1 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.2591794657841824 | [965] | [1515,1167,920,1061] | 5 | hSpCas9 | negative selection | 9097280 | 48029362 | 48029385 | 18 | + | 27260156 | SKES1 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.42370851514326957 | [468] | [824,616,598,503] | 8 | hSpCas9 | negative selection | 9161525 | 48040793 | 48040816 | 18 | + | 27260156 | SKES1 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.11726260763864271 | [85] | [119,112,83,63] | 2 | hSpCas9 | negative selection | 9161526 | 48029754 | 48029777 | 18 | + | 27260156 | SKES1 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.5958041530118754 | [766] | [482,682,496,388] | -8 | hSpCas9 | negative selection | 9161527 | 48029818 | 48029841 | 18 | + | 27260156 | TOV112D | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.15104974209279934 | [474] | [356,474,511,375] | -3 | hSpCas9 | negative selection | 9218529 | 48040115 | 48040138 | 18 | + | 27260156 | TOV112D | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.5260496192796503 | [834] | [1391,1622,1190,740] | 8 | hSpCas9 | negative selection | 9218530 | 48040735 | 48040758 | 18 | - | 27260156 | TOV112D | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.14937386749865844 | [965] | [1069,1182,911,1149] | 3 | hSpCas9 | negative selection | 9218531 | 48029362 | 48029385 | 18 | + | 27260156 | TOV112D | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.39866690250500314 | [468] | [658,665,590,575] | 7 | hSpCas9 | negative selection | 9282776 | 48040793 | 48040816 | 18 | + | 27260156 | TOV112D | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.4338777272391221 | [85] | [50,307,71,76] | 7 | hSpCas9 | negative selection | 9282777 | 48029754 | 48029777 | 18 | + | 27260156 | TOV112D | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.4271758172261362 | [766] | [682,734,380,535] | -7 | hSpCas9 | negative selection | 9282778 | 48029818 | 48029841 | 18 | + | 27260156 | TC71 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.4720333942691795 | [474] | [358,374,401,328] | -8 | hSpCas9 | negative selection | 9339780 | 48040115 | 48040138 | 18 | + | 27260156 | TC71 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.4023551377735598 | [834] | [1136,1250,1117,1231] | 8 | hSpCas9 | negative selection | 9339781 | 48040735 | 48040758 | 18 | - | 27260156 | TC71 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | -0.19330726266329157 | [965] | [907,752,818,1160] | -5 | hSpCas9 | negative selection | 9339782 | 48029362 | 48029385 | 18 | + | 27260156 | TC71 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.043540210002637525 | [468] | [609,401,427,640] | 1 | hSpCas9 | negative selection | 9404027 | 48040793 | 48040816 | 18 | + | 27260156 | TC71 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.42604134492049806 | [85] | [74,109,90,227] | 8 | hSpCas9 | negative selection | 9404028 | 48029754 | 48029777 | 18 | + | 27260156 | TC71 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.4299762630090037 | [766] | [571,658,483,738] | -8 | hSpCas9 | negative selection | 9404029 | 48029818 | 48029841 | 18 | + | 27260156 | TC32 | viability | GTCGTAGTTGTGCACGAACTTGG | ZBTB7C | ENSG00000184828 | -0.1127767588319006 | [474] | [458,247,511,485] | -2 | hSpCas9 | negative selection | 9461031 | 48040115 | 48040138 | 18 | + | 27260156 | TC32 | viability | GTAGTCGTTCTCCGCCTTGATGG | ZBTB7C | ENSG00000184828 | 0.4312156769252543 | [834] | [789,1004,1363,1117] | 7 | hSpCas9 | negative selection | 9461032 | 48040735 | 48040758 | 18 | - | 27260156 | TC32 | viability | GTGCATCGTGAACGTGTGCCTGG | ZBTB7C | ENSG00000184828 | 0.4570925596187141 | [965] | [1251,906,1475,1453] | 7 | hSpCas9 | negative selection | 9461033 | 48029362 | 48029385 | 18 | + | 27260156 | TC32 | viability | CCGCGCCGCCGCCACGTTCTCGG | ZBTB7C | ENSG00000184828 | 0.5683227097936779 | [468] | [706,419,882,688] | 8 | hSpCas9 | negative selection | 9525278 | 48040793 | 48040816 | 18 | + | 27260156 | TC32 | viability | CTTGACATTGCCAGCGGTGATGG | ZBTB7C | ENSG00000184828 | 0.2756159812997021 | [85] | [73,53,203,91] | 5 | hSpCas9 | negative selection | 9525279 | 48029754 | 48029777 | 18 | + | 27260156 | TC32 | viability | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.1829466015145833 | [766] | [516,683,552,730] | -3 | hSpCas9 | negative selection | 9525280 | 48029373 | 48029396 | 18 | - | 27869803 | HPAFII | viability after 27 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 0.5577860482230828 | [77] | [79,43,NaN] | 4 | hSpCas9 | negative selection | 9564651 | 48029754 | 48029777 | 18 | + | 27869803 | HPAFII | viability after 27 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.05865560092019728 | [302] | [154,174,NaN] | 0 | hSpCas9 | negative selection | 9564652 | 48040034 | 48040057 | 18 | + | 27869803 | HPAFII | viability after 27 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.5866633069977963 | [291] | [259,205,NaN] | 5 | hSpCas9 | negative selection | 9564653 | 48040035 | 48040058 | 18 | + | 27869803 | HPAFII | viability after 27 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.41623406669986573 | [144] | [68,128,NaN] | 3 | hSpCas9 | negative selection | 9564654 | 48040600 | 48040623 | 18 | - | 27869803 | HPAFII | viability after 27 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 1.0763137510171084 | [256] | [225,333,NaN] | 8 | hSpCas9 | negative selection | 9564655 | 48040787 | 48040810 | 18 | + | 27869803 | HPAFII | viability after 27 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 1.0999561999192298 | [100] | [115,111,NaN] | 8 | hSpCas9 | negative selection | 9564656 | 48029373 | 48029396 | 18 | - | 27869803 | HPAFII | viability after 15 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | -0.2973104462640337 | [77] | [74,63,NaN] | -3 | hSpCas9 | negative selection | 9647100 | 48029754 | 48029777 | 18 | + | 27869803 | HPAFII | viability after 15 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.18328082625710002 | [302] | [390,221,NaN] | -2 | hSpCas9 | negative selection | 9647101 | 48040034 | 48040057 | 18 | + | 27869803 | HPAFII | viability after 15 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.5675511548462913 | [291] | [654,346,NaN] | 6 | hSpCas9 | negative selection | 9647102 | 48040035 | 48040058 | 18 | + | 27869803 | HPAFII | viability after 15 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.17962655789343573 | [144] | [157,187,NaN] | 2 | hSpCas9 | negative selection | 9647103 | 48040600 | 48040623 | 18 | - | 27869803 | HPAFII | viability after 15 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.727193142939053 | [256] | [299,554,NaN] | 7 | hSpCas9 | negative selection | 9647104 | 48040787 | 48040810 | 18 | + | 27869803 | HPAFII | viability after 15 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 1.045828995740188 | [100] | [249,207,NaN] | 9 | hSpCas9 | negative selection | 9647105 | 48029373 | 48029396 | 18 | - | 27869803 | ASPC1 | viability after 36 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | -0.7639764946832652 | [174] | [49,46,16] | -6 | hSpCas9 | negative selection | 9729549 | 48029754 | 48029777 | 18 | + | 27869803 | ASPC1 | viability after 36 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.46935679816512127 | [627] | [853,120,58] | 5 | hSpCas9 | negative selection | 9729550 | 48040034 | 48040057 | 18 | + | 27869803 | ASPC1 | viability after 36 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.9690773984358486 | [731] | [270,839,385] | 8 | hSpCas9 | negative selection | 9729551 | 48040035 | 48040058 | 18 | + | 27869803 | ASPC1 | viability after 36 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.6076631391979704 | [440] | [222,317,173] | 6 | hSpCas9 | negative selection | 9729552 | 48040600 | 48040623 | 18 | - | 27869803 | ASPC1 | viability after 36 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.5830220785273602 | [400] | [370,199,101] | 6 | hSpCas9 | negative selection | 9729553 | 48040787 | 48040810 | 18 | + | 27869803 | ASPC1 | viability after 36 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.6887842074355002 | [375] | [254,92,272] | 6 | hSpCas9 | negative selection | 9729554 | 48029373 | 48029396 | 18 | - | 27869803 | PATU8988S | viability after 35 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 0.6682409545604799 | [135] | [105,67,NaN] | 7 | hSpCas9 | negative selection | 9811998 | 48029754 | 48029777 | 18 | + | 27869803 | PATU8988S | viability after 35 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.33732035885459066 | [602] | [231,381,NaN] | 4 | hSpCas9 | negative selection | 9811999 | 48040034 | 48040057 | 18 | + | 27869803 | PATU8988S | viability after 35 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.22191799461564687 | [674] | [343,289,NaN] | 2 | hSpCas9 | negative selection | 9812000 | 48040035 | 48040058 | 18 | + | 27869803 | PATU8988S | viability after 35 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | -0.07768956469009014 | [354] | [126,143,NaN] | -1 | hSpCas9 | negative selection | 9812001 | 48040600 | 48040623 | 18 | - | 27869803 | PATU8988S | viability after 35 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.24153136312443257 | [567] | [249,290,NaN] | 2 | hSpCas9 | negative selection | 9812002 | 48040787 | 48040810 | 18 | + | 27869803 | PATU8988S | viability after 35 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.8274243789389776 | [355] | [222,285,NaN] | 8 | hSpCas9 | negative selection | 9812003 | 48029373 | 48029396 | 18 | - | 27869803 | PATU8988S | viability after 31 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 0.6154620122244665 | [135] | [90,72,NaN] | 7 | hSpCas9 | negative selection | 9894447 | 48029754 | 48029777 | 18 | + | 27869803 | PATU8988S | viability after 31 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.2637477117183261 | [602] | [256,328,NaN] | 3 | hSpCas9 | negative selection | 9894448 | 48040034 | 48040057 | 18 | + | 27869803 | PATU8988S | viability after 31 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | -0.17120438803712942 | [674] | [209,275,NaN] | -2 | hSpCas9 | negative selection | 9894449 | 48040035 | 48040058 | 18 | + | 27869803 | PATU8988S | viability after 31 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | -0.04600634523493485 | [354] | [93,191,NaN] | 0 | hSpCas9 | negative selection | 9894450 | 48040600 | 48040623 | 18 | - | 27869803 | PATU8988S | viability after 31 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.5867266729005771 | [567] | [267,431,NaN] | 7 | hSpCas9 | negative selection | 9894451 | 48040787 | 48040810 | 18 | + | 27869803 | PATU8988S | viability after 31 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.6017995516946663 | [355] | [159,285,NaN] | 7 | hSpCas9 | negative selection | 9894452 | 48029373 | 48029396 | 18 | - | 27869803 | HPAFII | viability after 35 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 0.3080173633649641 | [77] | [54,41,NaN] | 2 | hSpCas9 | negative selection | 9976896 | 48029754 | 48029777 | 18 | + | 27869803 | HPAFII | viability after 35 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | -0.025591447373119247 | [302] | [129,173,NaN] | 0 | hSpCas9 | negative selection | 9976897 | 48040034 | 48040057 | 18 | + | 27869803 | HPAFII | viability after 35 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.6811275407828697 | [291] | [276,191,NaN] | 4 | hSpCas9 | negative selection | 9976898 | 48040035 | 48040058 | 18 | + | 27869803 | HPAFII | viability after 35 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.04198079115554132 | [144] | [44,109,NaN] | 0 | hSpCas9 | negative selection | 9976899 | 48040600 | 48040623 | 18 | - | 27869803 | HPAFII | viability after 35 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.8634497620084488 | [256] | [128,357,NaN] | 5 | hSpCas9 | negative selection | 9976900 | 48040787 | 48040810 | 18 | + | 27869803 | HPAFII | viability after 35 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.9164818292747487 | [100] | [56,140,NaN] | 6 | hSpCas9 | negative selection | 9976901 | 48029373 | 48029396 | 18 | - | 27869803 | HPAFII | viability after 31 days | CTTCGCGCTGGCCGAGAACGTGG | ZBTB7C | ENSG00000184828 | 0.7988764306178772 | [77] | [101,47,NaN] | 6 | hSpCas9 | negative selection | 10059345 | 48029754 | 48029777 | 18 | + | 27869803 | HPAFII | viability after 31 days | TCTTGTAGCAGAACTCGCACTGG | ZBTB7C | ENSG00000184828 | 0.32534219177246015 | [302] | [247,174,NaN] | 2 | hSpCas9 | negative selection | 10059346 | 48040034 | 48040057 | 18 | + | 27869803 | HPAFII | viability after 31 days | CAGCTTGCGCTCTTCTACCAGGG | ZBTB7C | ENSG00000184828 | 0.7147025034482498 | [291] | [289,245,NaN] | 5 | hSpCas9 | negative selection | 10059347 | 48040035 | 48040058 | 18 | + | 27869803 | HPAFII | viability after 31 days | AGCTTGCGCTCTTCTACCAGGGG | ZBTB7C | ENSG00000184828 | 0.3658417133277441 | [144] | [45,168,NaN] | 2 | hSpCas9 | negative selection | 10059348 | 48040600 | 48040623 | 18 | - | 27869803 | HPAFII | viability after 31 days | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 1.11473337805962 | [256] | [185,449,NaN] | 8 | hSpCas9 | negative selection | 10059349 | 48040787 | 48040810 | 18 | + | 27869803 | HPAFII | viability after 31 days | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.7803746416710685 | [100] | [82,112,NaN] | 6 | hSpCas9 | negative selection | 10059350 | 48040600 | 48040623 | 18 | - | 28162770 | P31FUJ | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | -0.33009940576929375 | [137] | [128] | -3 | hSpCas9 | negative selection | 10267379 | 48040990 | 48041013 | 18 | - | 28162770 | P31FUJ | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.4133005911206815 | [615] | [963] | 4 | hSpCas9 | negative selection | 10267380 | 48040945 | 48040968 | 18 | + | 28162770 | P31FUJ | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | 0.9192008890306713 | [17] | [39] | 9 | hSpCas9 | negative selection | 10267381 | 48040787 | 48040810 | 18 | + | 28162770 | P31FUJ | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.38868617233189173 | [77] | [119] | 4 | hSpCas9 | negative selection | 10267382 | 48040350 | 48040373 | 18 | + | 28162770 | P31FUJ | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | -0.3063312398363439 | [160] | [152] | -3 | hSpCas9 | negative selection | 10267383 | 48040330 | 48040353 | 18 | + | 28162770 | P31FUJ | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | 0.15951521836438154 | [79] | [104] | 1 | hSpCas9 | negative selection | 10267384 | 48040282 | 48040305 | 18 | - | 28162770 | P31FUJ | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | 1.4258173380320867 | [69] | [220] | 9 | hSpCas9 | negative selection | 10267385 | 48040234 | 48040257 | 18 | - | 28162770 | P31FUJ | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | 0.7463190659097056 | [173] | [342] | 8 | hSpCas9 | negative selection | 10267386 | 48039948 | 48039971 | 18 | + | 28162770 | P31FUJ | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | 0.1449221363964095 | [704] | [915] | 1 | hSpCas9 | negative selection | 10267387 | 48041024 | 48041047 | 18 | - | 28162770 | P31FUJ | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | -0.09704846261440336 | [374] | [411] | -1 | hSpCas9 | negative selection | 10267388 | 48040600 | 48040623 | 18 | - | 28162770 | TF1 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | NaN | [NaN] | [94] | 1 | hSpCas9 | negative selection | 10436745 | 48040990 | 48041013 | 18 | - | 28162770 | TF1 | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | NaN | [NaN] | [518] | 1 | hSpCas9 | negative selection | 10436746 | 48040945 | 48040968 | 18 | + | 28162770 | TF1 | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | NaN | [NaN] | [32] | 1 | hSpCas9 | negative selection | 10436747 | 48040787 | 48040810 | 18 | + | 28162770 | TF1 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | NaN | [NaN] | [37] | 1 | hSpCas9 | negative selection | 10436748 | 48040350 | 48040373 | 18 | + | 28162770 | TF1 | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | NaN | [NaN] | [107] | 1 | hSpCas9 | negative selection | 10436749 | 48040330 | 48040353 | 18 | + | 28162770 | TF1 | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | NaN | [NaN] | [148] | 1 | hSpCas9 | negative selection | 10436750 | 48040282 | 48040305 | 18 | - | 28162770 | TF1 | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | NaN | [NaN] | [71] | 1 | hSpCas9 | negative selection | 10436751 | 48040234 | 48040257 | 18 | - | 28162770 | TF1 | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | NaN | [NaN] | [69] | 1 | hSpCas9 | negative selection | 10436752 | 48039948 | 48039971 | 18 | + | 28162770 | TF1 | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | NaN | [NaN] | [595] | 1 | hSpCas9 | negative selection | 10436753 | 48041024 | 48041047 | 18 | - | 28162770 | TF1 | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | NaN | [NaN] | [286] | 1 | hSpCas9 | negative selection | 10436754 | 48040600 | 48040623 | 18 | - | 28162770 | SKM1 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 1.6042630566800926 | [23] | [128] | 9 | hSpCas9 | negative selection | 10606111 | 48040990 | 48041013 | 18 | - | 28162770 | SKM1 | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.13069258719963783 | [123] | [239] | 1 | hSpCas9 | negative selection | 10606112 | 48040945 | 48040968 | 18 | + | 28162770 | SKM1 | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | 0.5930358012568386 | [5] | [15] | 6 | hSpCas9 | negative selection | 10606113 | 48040787 | 48040810 | 18 | + | 28162770 | SKM1 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.659867309735047 | [28] | [80] | 6 | hSpCas9 | negative selection | 10606114 | 48040350 | 48040373 | 18 | + | 28162770 | SKM1 | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | 0.05485007120512956 | [54] | [100] | 0 | hSpCas9 | negative selection | 10606115 | 48040330 | 48040353 | 18 | + | 28162770 | SKM1 | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | -1.0443941193584534 | [20] | [17] | -6 | hSpCas9 | negative selection | 10606116 | 48040282 | 48040305 | 18 | - | 28162770 | SKM1 | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | 0.9990281609326753 | [14] | [52] | 8 | hSpCas9 | negative selection | 10606117 | 48040234 | 48040257 | 18 | - | 28162770 | SKM1 | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | -0.5648438585248808 | [40] | [48] | -4 | hSpCas9 | negative selection | 10606118 | 48039948 | 48039971 | 18 | + | 28162770 | SKM1 | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | -0.03857679276313952 | [164] | [283] | 0 | hSpCas9 | negative selection | 10606119 | 48041024 | 48041047 | 18 | - | 28162770 | SKM1 | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.12963528041659533 | [90] | [175] | 1 | hSpCas9 | negative selection | 10606120 | 48040600 | 48040623 | 18 | - | 28162770 | SKM1 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 1.6042630566800926 | [23] | [128] | 9 | hSpCas9 | negative selection | 10775477 | 48040990 | 48041013 | 18 | - | 28162770 | SKM1 | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.13069258719963783 | [123] | [239] | 1 | hSpCas9 | negative selection | 10775478 | 48040945 | 48040968 | 18 | + | 28162770 | SKM1 | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | 0.5930358012568386 | [5] | [15] | 6 | hSpCas9 | negative selection | 10775479 | 48040787 | 48040810 | 18 | + | 28162770 | SKM1 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.659867309735047 | [28] | [80] | 6 | hSpCas9 | negative selection | 10775480 | 48040350 | 48040373 | 18 | + | 28162770 | SKM1 | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | 0.05485007120512956 | [54] | [100] | 0 | hSpCas9 | negative selection | 10775481 | 48040330 | 48040353 | 18 | + | 28162770 | SKM1 | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | -1.0443941193584534 | [20] | [17] | -6 | hSpCas9 | negative selection | 10775482 | 48040282 | 48040305 | 18 | - | 28162770 | SKM1 | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | 0.9990281609326753 | [14] | [52] | 8 | hSpCas9 | negative selection | 10775483 | 48040234 | 48040257 | 18 | - | 28162770 | SKM1 | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | -0.5648438585248808 | [40] | [48] | -4 | hSpCas9 | negative selection | 10775484 | 48039948 | 48039971 | 18 | + | 28162770 | SKM1 | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | -0.03857679276313952 | [164] | [283] | 0 | hSpCas9 | negative selection | 10775485 | 48041024 | 48041047 | 18 | - | 28162770 | SKM1 | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.12963528041659533 | [90] | [175] | 1 | hSpCas9 | negative selection | 10775486 | 48040600 | 48040623 | 18 | - | 28162770 | PL21 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 1.9267632644340673 | [83] | [138] | 9 | hSpCas9 | negative selection | 10944843 | 48040990 | 48041013 | 18 | - | 28162770 | PL21 | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.5986889909795949 | [351] | [231] | 5 | hSpCas9 | negative selection | 10944844 | 48040945 | 48040968 | 18 | + | 28162770 | PL21 | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | -3.1217884803980427 | [19] | [0] | -9 | hSpCas9 | negative selection | 10944845 | 48040787 | 48040810 | 18 | + | 28162770 | PL21 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.3568651181767732 | [121] | [67] | 3 | hSpCas9 | negative selection | 10944846 | 48040350 | 48040373 | 18 | + | 28162770 | PL21 | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | 0.45167838148528455 | [167] | [99] | 4 | hSpCas9 | negative selection | 10944847 | 48040330 | 48040353 | 18 | + | 28162770 | PL21 | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | -0.607215307568284 | [62] | [17] | -4 | hSpCas9 | negative selection | 10944848 | 48040282 | 48040305 | 18 | - | 28162770 | PL21 | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | 1.1400186220517492 | [48] | [46] | 8 | hSpCas9 | negative selection | 10944849 | 48040234 | 48040257 | 18 | - | 28162770 | PL21 | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | -0.8122441099665124 | [116] | [28] | -5 | hSpCas9 | negative selection | 10944850 | 48039948 | 48039971 | 18 | + | 28162770 | PL21 | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | -0.15177779875269648 | [558] | [218] | -1 | hSpCas9 | negative selection | 10944851 | 48041024 | 48041047 | 18 | - | 28162770 | PL21 | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.6207798199975396 | [256] | [171] | 5 | hSpCas9 | negative selection | 10944852 | 48040600 | 48040623 | 18 | - | 28162770 | P31FUJ | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | -0.33009940576929375 | [137] | [128] | -3 | hSpCas9 | negative selection | 11114209 | 48040990 | 48041013 | 18 | - | 28162770 | P31FUJ | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.4133005911206815 | [615] | [963] | 4 | hSpCas9 | negative selection | 11114210 | 48040945 | 48040968 | 18 | + | 28162770 | P31FUJ | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | 0.9192008890306713 | [17] | [39] | 9 | hSpCas9 | negative selection | 11114211 | 48040787 | 48040810 | 18 | + | 28162770 | P31FUJ | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.38868617233189173 | [77] | [119] | 4 | hSpCas9 | negative selection | 11114212 | 48040350 | 48040373 | 18 | + | 28162770 | P31FUJ | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | -0.3063312398363439 | [160] | [152] | -3 | hSpCas9 | negative selection | 11114213 | 48040330 | 48040353 | 18 | + | 28162770 | P31FUJ | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | 0.15951521836438154 | [79] | [104] | 1 | hSpCas9 | negative selection | 11114214 | 48040282 | 48040305 | 18 | - | 28162770 | P31FUJ | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | 1.4258173380320867 | [69] | [220] | 9 | hSpCas9 | negative selection | 11114215 | 48040234 | 48040257 | 18 | - | 28162770 | P31FUJ | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | 0.7463190659097056 | [173] | [342] | 8 | hSpCas9 | negative selection | 11114216 | 48039948 | 48039971 | 18 | + | 28162770 | P31FUJ | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | 0.1449221363964095 | [704] | [915] | 1 | hSpCas9 | negative selection | 11114217 | 48041024 | 48041047 | 18 | - | 28162770 | P31FUJ | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | -0.09704846261440336 | [374] | [411] | -1 | hSpCas9 | negative selection | 11114218 | 48040600 | 48040623 | 18 | - | 28162770 | OCIAML5 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.8146900210208065 | [39] | [126] | 7 | hSpCas9 | negative selection | 11283575 | 48040990 | 48041013 | 18 | - | 28162770 | OCIAML5 | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.6665935594890045 | [281] | [807] | 6 | hSpCas9 | negative selection | 11283576 | 48040945 | 48040968 | 18 | + | 28162770 | OCIAML5 | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | -0.5301384759766345 | [11] | [14] | -4 | hSpCas9 | negative selection | 11283577 | 48040787 | 48040810 | 18 | + | 28162770 | OCIAML5 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.6355987285022441 | [45] | [128] | 5 | hSpCas9 | negative selection | 11283578 | 48040350 | 48040373 | 18 | + | 28162770 | OCIAML5 | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | 0.13065543770416754 | [83] | [165] | 1 | hSpCas9 | negative selection | 11283579 | 48040330 | 48040353 | 18 | + | 28162770 | OCIAML5 | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | 1.1288246061882985 | [37] | [149] | 8 | hSpCas9 | negative selection | 11283580 | 48040282 | 48040305 | 18 | - | 28162770 | OCIAML5 | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | 0.21352177076357992 | [42] | [89] | 1 | hSpCas9 | negative selection | 11283581 | 48040234 | 48040257 | 18 | - | 28162770 | OCIAML5 | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | 0.5360038808145776 | [80] | [211] | 4 | hSpCas9 | negative selection | 11283582 | 48039948 | 48039971 | 18 | + | 28162770 | OCIAML5 | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | -0.03171176224100658 | [362] | [640] | 0 | hSpCas9 | negative selection | 11283583 | 48041024 | 48041047 | 18 | - | 28162770 | OCIAML5 | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | -0.06111455981746228 | [277] | [480] | 0 | hSpCas9 | negative selection | 11283584 | 48040600 | 48040623 | 18 | - | 28162770 | EOL1 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | -0.7148625131729979 | [242] | [77] | -5 | hSpCas9 | negative selection | 11452941 | 48040990 | 48041013 | 18 | - | 28162770 | EOL1 | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.7004244621549708 | [555] | [475] | 6 | hSpCas9 | negative selection | 11452942 | 48040945 | 48040968 | 18 | + | 28162770 | EOL1 | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | -2.6604147291506215 | [47] | [3] | -9 | hSpCas9 | negative selection | 11452943 | 48040787 | 48040810 | 18 | + | 28162770 | EOL1 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | -0.6309709512581394 | [193] | [65] | -4 | hSpCas9 | negative selection | 11452944 | 48040350 | 48040373 | 18 | + | 28162770 | EOL1 | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | -0.2892315194612053 | [333] | [143] | -2 | hSpCas9 | negative selection | 11452945 | 48040330 | 48040353 | 18 | + | 28162770 | EOL1 | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | -0.30087234246348116 | [158] | [67] | -2 | hSpCas9 | negative selection | 11452946 | 48040282 | 48040305 | 18 | - | 28162770 | EOL1 | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | 1.1875821774043285 | [49] | [59] | 8 | hSpCas9 | negative selection | 11452947 | 48040234 | 48040257 | 18 | - | 28162770 | EOL1 | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | -0.31491816312485477 | [169] | [71] | -2 | hSpCas9 | negative selection | 11452948 | 48039948 | 48039971 | 18 | + | 28162770 | EOL1 | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | 0.4046642504921807 | [660] | [460] | 3 | hSpCas9 | negative selection | 11452949 | 48041024 | 48041047 | 18 | - | 28162770 | EOL1 | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.06656677644296244 | [405] | [223] | 0 | hSpCas9 | negative selection | 11452950 | 48040600 | 48040623 | 18 | - | 28162770 | MOLM13 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.4926927725451514 | [172] | [175] | 3 | hSpCas9 | negative selection | 11622307 | 48040990 | 48041013 | 18 | - | 28162770 | MOLM13 | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.21717524734665283 | [582] | [489] | 1 | hSpCas9 | negative selection | 11622308 | 48040945 | 48040968 | 18 | + | 28162770 | MOLM13 | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | -4.28699812061889 | [26] | [0] | -9 | hSpCas9 | negative selection | 11622309 | 48040787 | 48040810 | 18 | + | 28162770 | MOLM13 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 1.1653266115241474 | [147] | [239] | 8 | hSpCas9 | negative selection | 11622310 | 48040350 | 48040373 | 18 | + | 28162770 | MOLM13 | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | 0.00011042019376167334 | [259] | [187] | 0 | hSpCas9 | negative selection | 11622311 | 48040330 | 48040353 | 18 | + | 28162770 | MOLM13 | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | 0.9854239547454445 | [145] | [208] | 7 | hSpCas9 | negative selection | 11622312 | 48040282 | 48040305 | 18 | - | 28162770 | MOLM13 | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | 2.0418807644447323 | [43] | [130] | 9 | hSpCas9 | negative selection | 11622313 | 48040234 | 48040257 | 18 | - | 28162770 | MOLM13 | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | 1.2082455649115593 | [169] | [283] | 8 | hSpCas9 | negative selection | 11622314 | 48039948 | 48039971 | 18 | + | 28162770 | MOLM13 | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | 0.3319244981913001 | [655] | [596] | 2 | hSpCas9 | negative selection | 11622315 | 48041024 | 48041047 | 18 | - | 28162770 | MOLM13 | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.1239349803272175 | [461] | [363] | 0 | hSpCas9 | negative selection | 11622316 | 48040600 | 48040623 | 18 | - | 28162770 | HEL | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | -0.21104042714859916 | [149] | [82] | -1 | hSpCas9 | negative selection | 11791673 | 48040990 | 48041013 | 18 | - | 28162770 | HEL | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.349187999643499 | [515] | [420] | 3 | hSpCas9 | negative selection | 11791674 | 48040945 | 48040968 | 18 | + | 28162770 | HEL | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | -0.9852923906126851 | [33] | [10] | -6 | hSpCas9 | negative selection | 11791675 | 48040787 | 48040810 | 18 | + | 28162770 | HEL | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.3942405193244435 | [157] | [132] | 3 | hSpCas9 | negative selection | 11791676 | 48040350 | 48040373 | 18 | + | 28162770 | HEL | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | -0.31595419384272944 | [240] | [123] | -2 | hSpCas9 | negative selection | 11791677 | 48040330 | 48040353 | 18 | + | 28162770 | HEL | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | -0.44265265923028774 | [86] | [40] | -3 | hSpCas9 | negative selection | 11791678 | 48040282 | 48040305 | 18 | - | 28162770 | HEL | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | -0.03533307311228073 | [55] | [34] | 0 | hSpCas9 | negative selection | 11791679 | 48040234 | 48040257 | 18 | - | 28162770 | HEL | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | -1.0220769764100137 | [129] | [40] | -6 | hSpCas9 | negative selection | 11791680 | 48039948 | 48039971 | 18 | + | 28162770 | HEL | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | -0.1216329195065009 | [619] | [364] | -1 | hSpCas9 | negative selection | 11791681 | 48041024 | 48041047 | 18 | - | 28162770 | HEL | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | -0.4420415881966625 | [402] | [189] | -3 | hSpCas9 | negative selection | 11791682 | 48040600 | 48040623 | 18 | - | 28162770 | MV411 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.12068040849683648 | [106] | [97] | 1 | hSpCas9 | negative selection | 11961039 | 48040990 | 48041013 | 18 | - | 28162770 | MV411 | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 1.0074867580620226 | [433] | [734] | 8 | hSpCas9 | negative selection | 11961040 | 48040945 | 48040968 | 18 | + | 28162770 | MV411 | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | -1.5180971955802014 | [16] | [4] | -7 | hSpCas9 | negative selection | 11961041 | 48040787 | 48040810 | 18 | + | 28162770 | MV411 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 1.1405223468662633 | [125] | [233] | 8 | hSpCas9 | negative selection | 11961042 | 48040350 | 48040373 | 18 | + | 28162770 | MV411 | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | -0.08959743649479535 | [167] | [132] | 0 | hSpCas9 | negative selection | 11961043 | 48040330 | 48040353 | 18 | + | 28162770 | MV411 | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | -1.1310740724709545 | [90] | [34] | -6 | hSpCas9 | negative selection | 11961044 | 48040282 | 48040305 | 18 | - | 28162770 | MV411 | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | 0.2474375507827753 | [45] | [45] | 2 | hSpCas9 | negative selection | 11961045 | 48040234 | 48040257 | 18 | - | 28162770 | MV411 | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | 0.0028151820628617985 | [108] | [91] | 0 | hSpCas9 | negative selection | 11961046 | 48039948 | 48039971 | 18 | + | 28162770 | MV411 | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | 0.3276078994667586 | [419] | [443] | 3 | hSpCas9 | negative selection | 11961047 | 48041024 | 48041047 | 18 | - | 28162770 | MV411 | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.19796887451847556 | [266] | [257] | 1 | hSpCas9 | negative selection | 11961048 | 48040600 | 48040623 | 18 | - | 28162770 | MONOMAC1 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.4634766866687794 | [61] | [97] | 4 | hSpCas9 | negative selection | 12130405 | 48040990 | 48041013 | 18 | - | 28162770 | MONOMAC1 | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.10858943549870825 | [266] | [329] | 1 | hSpCas9 | negative selection | 12130406 | 48040945 | 48040968 | 18 | + | 28162770 | MONOMAC1 | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | -0.19703684705955382 | [10] | [10] | -2 | hSpCas9 | negative selection | 12130407 | 48040787 | 48040810 | 18 | + | 28162770 | MONOMAC1 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.21260739344907187 | [66] | [88] | 2 | hSpCas9 | negative selection | 12130408 | 48040350 | 48040373 | 18 | + | 28162770 | MONOMAC1 | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | 0.07807039107481499 | [118] | [143] | 0 | hSpCas9 | negative selection | 12130409 | 48040330 | 48040353 | 18 | + | 28162770 | MONOMAC1 | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | -0.9152658786441741 | [50] | [30] | -6 | hSpCas9 | negative selection | 12130410 | 48040282 | 48040305 | 18 | - | 28162770 | MONOMAC1 | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | -0.35457812404603395 | [28] | [25] | -3 | hSpCas9 | negative selection | 12130411 | 48040234 | 48040257 | 18 | - | 28162770 | MONOMAC1 | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | 0.3630509850225731 | [77] | [114] | 3 | hSpCas9 | negative selection | 12130412 | 48039948 | 48039971 | 18 | + | 28162770 | MONOMAC1 | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | -0.019863177879597904 | [374] | [423] | 0 | hSpCas9 | negative selection | 12130413 | 48041024 | 48041047 | 18 | - | 28162770 | MONOMAC1 | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.7891131741794221 | [156] | [310] | 7 | hSpCas9 | negative selection | 12130414 | 48040600 | 48040623 | 18 | - | 28162770 | OCIAML2 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | 0.8681720882095972 | [16] | [171] | 8 | hSpCas9 | negative selection | 12299771 | 48040990 | 48041013 | 18 | - | 28162770 | OCIAML2 | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.012311738538486106 | [82] | [463] | 0 | hSpCas9 | negative selection | 12299772 | 48040945 | 48040968 | 18 | + | 28162770 | OCIAML2 | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | 0.2842576769213072 | [3] | [26] | 2 | hSpCas9 | negative selection | 12299773 | 48040787 | 48040810 | 18 | + | 28162770 | OCIAML2 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | -1.8267736354674367 | [31] | [49] | -8 | hSpCas9 | negative selection | 12299774 | 48040350 | 48040373 | 18 | + | 28162770 | OCIAML2 | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | -0.760136442437146 | [32] | [107] | -5 | hSpCas9 | negative selection | 12299775 | 48040330 | 48040353 | 18 | + | 28162770 | OCIAML2 | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | -1.1318279117904029 | [16] | [42] | -6 | hSpCas9 | negative selection | 12299776 | 48040282 | 48040305 | 18 | - | 28162770 | OCIAML2 | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | -0.37109415169124693 | [13] | [59] | -3 | hSpCas9 | negative selection | 12299777 | 48040234 | 48040257 | 18 | - | 28162770 | OCIAML2 | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | -0.8491414484958912 | [25] | [79] | -5 | hSpCas9 | negative selection | 12299778 | 48039948 | 48039971 | 18 | + | 28162770 | OCIAML2 | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | 0.2862853582682898 | [78] | [533] | 2 | hSpCas9 | negative selection | 12299779 | 48041024 | 48041047 | 18 | - | 28162770 | OCIAML2 | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | 0.765437532991363 | [44] | [423] | 7 | hSpCas9 | negative selection | 12299780 | 48040600 | 48040623 | 18 | - | 28162770 | OCIAML3 | viability | GGATGACGATGATGACACGGAGG | ZBTB7C | ENSG00000184828 | -0.42067603743860144 | [46] | [105] | -3 | hSpCas9 | negative selection | 12469137 | 48040990 | 48041013 | 18 | - | 28162770 | OCIAML3 | viability | GCTGTGTGACGTGCTCCTGGTGG | ZBTB7C | ENSG00000184828 | 0.6923592693402543 | [114] | [560] | 6 | hSpCas9 | negative selection | 12469138 | 48040945 | 48040968 | 18 | + | 28162770 | OCIAML3 | viability | AGGCAGCCAGGACGGAGCGGTGG | ZBTB7C | ENSG00000184828 | 1.2133472817334408 | [2] | [20] | 8 | hSpCas9 | negative selection | 12469139 | 48040787 | 48040810 | 18 | + | 28162770 | OCIAML3 | viability | GATGTGCTTGACATTGCCAGCGG | ZBTB7C | ENSG00000184828 | 0.5170236720645807 | [24] | [107] | 5 | hSpCas9 | negative selection | 12469140 | 48040350 | 48040373 | 18 | + | 28162770 | OCIAML3 | viability | GGGGCGAATGGAGACAAGGAGGG | ZBTB7C | ENSG00000184828 | -0.5034050915432565 | [53] | [114] | -4 | hSpCas9 | negative selection | 12469141 | 48040330 | 48040353 | 18 | + | 28162770 | OCIAML3 | viability | AGAGGTGTGGAAAGAAGTCCGGG | ZBTB7C | ENSG00000184828 | -1.3500820574380739 | [37] | [44] | -7 | hSpCas9 | negative selection | 12469142 | 48040282 | 48040305 | 18 | - | 28162770 | OCIAML3 | viability | CCAGCTGCCTGAGCAGCCCATGG | ZBTB7C | ENSG00000184828 | -0.05795474008395374 | [9] | [28] | 0 | hSpCas9 | negative selection | 12469143 | 48040234 | 48040257 | 18 | - | 28162770 | OCIAML3 | viability | CAAGAATCGGAAGATCAAGGAGG | ZBTB7C | ENSG00000184828 | 0.801577496288508 | [41] | [220] | 7 | hSpCas9 | negative selection | 12469144 | 48039948 | 48039971 | 18 | + | 28162770 | OCIAML3 | viability | GTATGGGTCCTCATGTGCCGCGG | ZBTB7C | ENSG00000184828 | 0.3121485724530797 | [130] | [490] | 3 | hSpCas9 | negative selection | 12469145 | 48041024 | 48041047 | 18 | - | 28162770 | OCIAML3 | viability | TGTGCAGCCTCAATGAGCAACGG | ZBTB7C | ENSG00000184828 | -0.18891294429289784 | [90] | [240] | -1 | hSpCas9 | negative selection | 12469146 |