Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:84107
• Symbol:ZIC4
• Description:Zic family member 4

DataSource: http://genomecrispr.dkfz.de/#!/results/ZIC4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
147391036	147391059	3	+	26472758	Jiyoye	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	-0.03453006823505056	[181]	[133]	0	hSpCas9	negative selection	185306
147391163	147391186	3	+	26472758	Jiyoye	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	1.22138397460454	[119]	[210]	7	hSpCas9	negative selection	185307
147390987	147391010	3	+	26472758	Jiyoye	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	0.1936611115158784	[188]	[162]	1	hSpCas9	negative selection	185308
147390965	147390988	3	-	26472758	Jiyoye	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-1.9456136770862495	[188]	[36]	-8	hSpCas9	negative selection	185309
147390930	147390953	3	-	26472758	Jiyoye	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.23499440612319322	[159]	[141]	1	hSpCas9	negative selection	185311
147391127	147391150	3	-	26472758	Jiyoye	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	1.7877793837208436	[52]	[137]	8	hSpCas9	negative selection	185312
147391068	147391091	3	-	26472758	Jiyoye	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.007862117772970523	[219]	[164]	0	hSpCas9	negative selection	185313
147391006	147391029	3	+	26472758	Jiyoye	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	-1.0306334254316285	[148]	[54]	-6	hSpCas9	negative selection	185314
147391215	147391238	3	+	26472758	Jiyoye	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.03878797552585089	[70]	[54]	0	hSpCas9	negative selection	185315
147391036	147391059	3	+	26472758	KBM7	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.7641247864758043	[705,372]	[337,491]	8	hSpCas9	negative selection	376424
147391163	147391186	3	+	26472758	KBM7	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.5497379564470393	[452,721]	[532,310]	6	hSpCas9	negative selection	376425
147390987	147391010	3	+	26472758	KBM7	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	0.8100070307306467	[725,397]	[343,547]	8	hSpCas9	negative selection	376426
147390965	147390988	3	-	26472758	KBM7	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-1.4438845336748558	[838,547]	[176,64]	-7	hSpCas9	negative selection	376427
147390930	147390953	3	-	26472758	KBM7	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	1.1675867152338542	[718,738]	[636,897]	9	hSpCas9	negative selection	376429
147391127	147391150	3	-	26472758	KBM7	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	-0.06668530453222965	[552,591]	[255,261]	0	hSpCas9	negative selection	376430
147391068	147391091	3	-	26472758	KBM7	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.19348949652446534	[1368,1444]	[1096,462]	2	hSpCas9	negative selection	376431
147391006	147391029	3	+	26472758	KBM7	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	0.14192770055311618	[369,365]	[224,161]	1	hSpCas9	negative selection	376432
147391215	147391238	3	+	26472758	KBM7	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.5471107323632509	[586,565]	[467,333]	6	hSpCas9	negative selection	376433
147391036	147391059	3	+	26472758	Raji	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.6365920545717545	[254]	[91]	6	hSpCas9	negative selection	567542
147391163	147391186	3	+	26472758	Raji	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-0.2180590436899995	[410]	[81]	-2	hSpCas9	negative selection	567543
147390987	147391010	3	+	26472758	Raji	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	-0.033628774153474095	[246]	[55]	0	hSpCas9	negative selection	567544
147390965	147390988	3	-	26472758	Raji	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-1.1041205698201124	[351]	[37]	-7	hSpCas9	negative selection	567545
147390930	147390953	3	-	26472758	Raji	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	1.2338318706145386	[261]	[142]	9	hSpCas9	negative selection	567547
147391127	147391150	3	-	26472758	Raji	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	0.6334523470411872	[249]	[89]	6	hSpCas9	negative selection	567548
147391068	147391091	3	-	26472758	Raji	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.022061721042385907	[504]	[118]	0	hSpCas9	negative selection	567549
147391006	147391029	3	+	26472758	Raji	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	0.08818997014028854	[226]	[55]	0	hSpCas9	negative selection	567550
147391215	147391238	3	+	26472758	Raji	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.4243109492025955	[288]	[89]	4	hSpCas9	negative selection	567551
147391036	147391059	3	+	26472758	K562	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.6158210981359613	[578]	[748]	5	hSpCas9	negative selection	758660
147391163	147391186	3	+	26472758	K562	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.9813843218326529	[620]	[1034]	8	hSpCas9	negative selection	758661
147390987	147391010	3	+	26472758	K562	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	-0.2742012782260133	[509]	[355]	-2	hSpCas9	negative selection	758662
147390965	147390988	3	-	26472758	K562	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-4.377633091789929	[590]	[23]	-9	hSpCas9	negative selection	758663
147390930	147390953	3	-	26472758	K562	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.8533600913220429	[536]	[818]	7	hSpCas9	negative selection	758665
147391127	147391150	3	-	26472758	K562	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	0.8406965416154373	[380]	[575]	7	hSpCas9	negative selection	758666
147391068	147391091	3	-	26472758	K562	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.22821677540505036	[984]	[973]	1	hSpCas9	negative selection	758667
147391006	147391029	3	+	26472758	K562	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	0.7038503463037441	[159]	[219]	6	hSpCas9	negative selection	758668
147391215	147391238	3	+	26472758	K562	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.6734404563809918	[461]	[621]	5	hSpCas9	negative selection	758669
147390988	147391011	3	+	26627737	DLD1	viability	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.061946180091432046	[913]	[177,451,208]	0	hSpCas9	negative selection	819940
147391039	147391062	3	+	26627737	DLD1	viability	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-0.34482444486523955	[524]	[102,104,171]	-4	hSpCas9	negative selection	819941
147390988	147391011	3	+	26627737	GBM cells	viability after 5 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.5079957435097581	[353]	[159,106]	-7	hSpCas9	negative selection	902255
147391039	147391062	3	+	26627737	GBM cells	viability after 5 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-0.3764274263997216	[258]	[111,101]	-5	hSpCas9	negative selection	902256
147390988	147391011	3	+	26627737	GBM cells	viability after 13 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.7494520714464802	[353]	[132,98]	-7	hSpCas9	negative selection	984570
147391039	147391062	3	+	26627737	GBM cells	viability after 13 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-0.7316931405331099	[258]	[93,76]	-7	hSpCas9	negative selection	984571
147390988	147391011	3	+	26627737	GBM cells	viability after 21 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.6530916568273148	[353]	[126,117]	-5	hSpCas9	negative selection	1066885
147391039	147391062	3	+	26627737	GBM cells	viability after 21 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-1.1743858869304897	[258]	[65,58]	-7	hSpCas9	negative selection	1066886
147390988	147391011	3	+	26627737	RPE1	viability after 9 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	0.49679038777880835	[1193]	[602,429]	3	hSpCas9	negative selection	1149200
147391039	147391062	3	+	26627737	RPE1	viability after 9 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-0.22883408934310268	[771]	[262,132]	-2	hSpCas9	negative selection	1149201
147390988	147391011	3	+	26627737	RPE1	viability after 12 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	0.5412733415644168	[1193]	[443,490]	3	hSpCas9	negative selection	1231515
147391039	147391062	3	+	26627737	RPE1	viability after 12 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-0.7411524050860162	[771]	[211,30]	-5	hSpCas9	negative selection	1231516
147390988	147391011	3	+	26627737	RPE1	viability after 15 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	1.0568831776248913	[1193]	[1001,413]	6	hSpCas9	negative selection	1313830
147391039	147391062	3	+	26627737	RPE1	viability after 15 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-0.8013248979338161	[771]	[163,87]	-5	hSpCas9	negative selection	1313831
147390988	147391011	3	+	26627737	RPE1	viability after 18 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	0.9775305522471952	[1193]	[808,447]	6	hSpCas9	negative selection	1396145
147391039	147391062	3	+	26627737	RPE1	viability after 18 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-1.060300719349946	[771]	[67,133]	-6	hSpCas9	negative selection	1396146
147390988	147391011	3	+	26627737	HeLa	viability after 8 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-1.0887568726810648	[860]	[206,118,206]	-8	hSpCas9	negative selection	1478460
147391039	147391062	3	+	26627737	HeLa	viability after 8 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	0.08636854291079177	[516]	[331,387,31]	0	hSpCas9	negative selection	1478461
147390988	147391011	3	+	26627737	HeLa	viability after 12 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.7163720018335816	[860]	[322,138,198]	-6	hSpCas9	negative selection	1560775
147391039	147391062	3	+	26627737	HeLa	viability after 12 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-0.6932860145129451	[516]	[154,179,56]	-6	hSpCas9	negative selection	1560776
147390988	147391011	3	+	26627737	HeLa	viability after 15 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.4729898057766341	[860]	[332,189,231]	-4	hSpCas9	negative selection	1643090
147391039	147391062	3	+	26627737	HeLa	viability after 15 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-0.44983962839474173	[516]	[230,139,84]	-4	hSpCas9	negative selection	1643091
147390988	147391011	3	+	26627737	HeLa	viability after 18 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.4453324383251722	[860]	[229,160,231]	-4	hSpCas9	negative selection	1725405
147391039	147391062	3	+	26627737	HeLa	viability after 18 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-0.36539555525965006	[516]	[168,120,84]	-3	hSpCas9	negative selection	1725406
147390988	147391011	3	+	26627737	HCT116	viability after 6 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.47903038360659567	[1643]	[158,199]	-3	hSpCas9	negative selection	1807720
147391039	147391062	3	+	26627737	HCT116	viability after 6 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-0.5907744448697521	[1163]	[310,16]	-3	hSpCas9	negative selection	1807721
147390988	147391011	3	+	26627737	HCT116	viability after 8 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.33129480558527247	[479]	[228,190,210]	-4	hSpCas9	negative selection	1890035
147391039	147391062	3	+	26627737	HCT116	viability after 8 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	2.535300336330501	[46]	[173,58,216]	9	hSpCas9	negative selection	1890036
147390988	147391011	3	+	26627737	HCT116	viability after 9 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.20681585174002692	[1643]	[500,284]	-1	hSpCas9	negative selection	1972350
147391039	147391062	3	+	26627737	HCT116	viability after 9 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-1.6452870307302132	[1163]	[52,135]	-8	hSpCas9	negative selection	1972351
147390988	147391011	3	+	26627737	HCT116	viability after 12 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.4570477952778057	[479]	[168,159,222]	-5	hSpCas9	negative selection	2054665
147391039	147391062	3	+	26627737	HCT116	viability after 12 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	3.005033486256546	[46]	[221,165,203]	9	hSpCas9	negative selection	2054666
147390988	147391011	3	+	26627737	HCT116	viability after 15 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.4561892407112603	[479]	[196,260,144]	-5	hSpCas9	negative selection	2136980
147391039	147391062	3	+	26627737	HCT116	viability after 15 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	2.302540873400793	[46]	[198,117,90]	9	hSpCas9	negative selection	2136981
147390988	147391011	3	+	26627737	HCT116	viability after 18 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	0.2796748879278308	[479]	[284,186,383]	2	hSpCas9	negative selection	2219295
147391039	147391062	3	+	26627737	HCT116	viability after 18 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	2.6420801637735734	[46]	[228,41,161]	9	hSpCas9	negative selection	2219296
147391127	147391150	3	-	24336569	HL60	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	-0.17219387680446963	[524]	[985]	-1	hSpCas9	negative selection	2308765
147391133	147391156	3	-	24336569	HL60	viability	CGACAAGCCATACACGTGCAAGG	ZIC4	ENSG00000174963	0.7950528459361033	[255]	[939]	6	hSpCas9	negative selection	2308766
147391163	147391186	3	+	24336569	HL60	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-0.8542546629946725	[298]	[349]	-6	hSpCas9	negative selection	2308767
147391206	147391229	3	-	24336569	HL60	viability	GCGAGTTCGAGGGCTGCGAGCGG	ZIC4	ENSG00000174963	-1.1445555562863665	[1261]	[1207]	-8	hSpCas9	negative selection	2308768
147391215	147391238	3	+	24336569	HL60	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	-0.24496283291177567	[41]	[74]	-2	hSpCas9	negative selection	2308769
147391228	147391251	3	+	24336569	HL60	viability	CATCTGAAGGGCTTCTCGCCTGG	ZIC4	ENSG00000174963	0.482169890651748	[476]	[1409]	4	hSpCas9	negative selection	2308770
147391127	147391150	3	-	24336569	KBM7	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	-0.15975895598178452	[427]	[1044]	-1	hSpCas9	negative selection	2375942
147391133	147391156	3	-	24336569	KBM7	viability	CGACAAGCCATACACGTGCAAGG	ZIC4	ENSG00000174963	-0.46681541541180005	[452]	[893]	-4	hSpCas9	negative selection	2375943
147391163	147391186	3	+	24336569	KBM7	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.4579168169878831	[137]	[516]	4	hSpCas9	negative selection	2375944
147391206	147391229	3	-	24336569	KBM7	viability	GCGAGTTCGAGGGCTGCGAGCGG	ZIC4	ENSG00000174963	-0.032824384650366856	[637]	[1700]	0	hSpCas9	negative selection	2375945
147391215	147391238	3	+	24336569	KBM7	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	1.1373833041722736	[110]	[665]	8	hSpCas9	negative selection	2375946
147391228	147391251	3	+	24336569	KBM7	viability	CATCTGAAGGGCTTCTCGCCTGG	ZIC4	ENSG00000174963	-0.12424428044727437	[409]	[1025]	-1	hSpCas9	negative selection	2375947
147391126	147391149	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCATACACGTGCAAGGTGCGGGG	ZIC4	ENSG00000174963	0.34041441264082895	[4,3]	[3,4]	7	hSpCas9	positive selection	3033740
147391217	147391240	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCCTCGAACTCGCATCTGAAGGG	ZIC4	ENSG00000174963	-0.6491210508472772	[3,3]	[3,0]	-7	hSpCas9	positive selection	3033741
147391216	147391239	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCCTTCAGATGCGAGTTCGAGGG	ZIC4	ENSG00000174963	0.24839854829299668	[2,2]	[2,2]	5	hSpCas9	positive selection	3033742
147391164	147391187	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.284128423543746	[4,4]	[4,4]	6	hSpCas9	positive selection	3033743
147391126	147391149	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCATACACGTGCAAGGTGCGGGG	ZIC4	ENSG00000174963	0.36213984904497765	[4,4]	[4,3]	6	hSpCas9	positive selection	3101598
147391217	147391240	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCCTCGAACTCGCATCTGAAGGG	ZIC4	ENSG00000174963	0.16960055944240587	[3,3]	[2,3]	3	hSpCas9	positive selection	3101599
147391216	147391239	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCCTTCAGATGCGAGTTCGAGGG	ZIC4	ENSG00000174963	0.23319038294047667	[2,2]	[2,1]	4	hSpCas9	positive selection	3101600
147391164	147391187	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-0.46457488444164774	[4,4]	[3,0]	-6	hSpCas9	positive selection	3101601
147390930	147390953		-	24336571	A375	resistance to PLX after 7 days	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	-0.06530780808061576	[23,28]	[24,25]	-2	hSpCas9	positive selection	3156859
147390930	147390953		-	24336571	A375	resistance to PLX after 14 days	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	-0.40353777131288004	[21,29]	[8,7]	-5	hSpCas9	positive selection	3214652
147390930	147390953		-	24336571	A375	viability after 7 days	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.14394871145473465	[24]	[23,28]	2	hSpCas9	negative selection	3272445
147390930	147390953		-	24336571	A375	viability after 14 days	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.10715983729988621	[24]	[21,29]	1	hSpCas9	negative selection	3330238
147391126	147391149	3	-	26780180	HT29	viability (Avana library 4 designs)	CCATACACGTGCAAGGTGCGGGG	ZIC4	ENSG00000174963	0.266820147532792	[]	[]	0	hSpCas9	negative selection	3473056
147391216	147391239	3	+	26780180	HT29	viability (Avana library 4 designs)	CCCTCGAACTCGCATCTGAAGGG	ZIC4	ENSG00000174963	0.883318532169453	[]	[]	3	hSpCas9	negative selection	3473057
147391216	147391239	3	-	26780180	HT29	viability (Avana library 4 designs)	CCCTTCAGATGCGAGTTCGAGGG	ZIC4	ENSG00000174963	0.158683424751333	[]	[]	0	hSpCas9	negative selection	3473058
147391163	147391186	3	+	26780180	HT29	viability (Avana library 4 designs)	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-0.591163437032722	[]	[]	-8	hSpCas9	negative selection	3473059
147391126	147391149	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCATACACGTGCAAGGTGCGGGG	ZIC4	ENSG00000174963	6.10750151125168	[]	[]	9	hSpCas9	negative selection	3580629
147391163	147391186	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	5.27691106143897	[]	[]	8	hSpCas9	negative selection	3580630
147391216	147391239	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCCTTCAGATGCGAGTTCGAGGG	ZIC4	ENSG00000174963	2.32102954078535	[]	[]	3	hSpCas9	negative selection	3580631
147391216	147391239	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCCTCGAACTCGCATCTGAAGGG	ZIC4	ENSG00000174963	4.57265577201456	[]	[]	7	hSpCas9	negative selection	3580632
147391206	147391229	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGAGTTCGAGGGCTGCGAGCGG	ZIC4	ENSG00000174963	2.96167404141908	[]	[]	4	hSpCas9	negative selection	3580633
147391126	147391149	3	-	26780180	A375	viability (Avana lentiGuide)	CCATACACGTGCAAGGTGCGGGG	ZIC4	ENSG00000174963	-0.728047950749417	[]	[]	-1	hSpCas9	negative selection	3689288
147391163	147391186	3	+	26780180	A375	viability (Avana lentiGuide)	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-4.05705087419873	[]	[]	-7	hSpCas9	negative selection	3689289
147391216	147391239	3	-	26780180	A375	viability (Avana lentiGuide)	CCCTTCAGATGCGAGTTCGAGGG	ZIC4	ENSG00000174963	-1.19260680708216	[]	[]	-2	hSpCas9	negative selection	3689290
147391216	147391239	3	+	26780180	A375	viability (Avana lentiGuide)	CCCTCGAACTCGCATCTGAAGGG	ZIC4	ENSG00000174963	-9.39294691488319	[]	[]	-9	hSpCas9	negative selection	3689291
147391206	147391229	3	-	26780180	A375	viability (Avana lentiGuide)	GCGAGTTCGAGGGCTGCGAGCGG	ZIC4	ENSG00000174963	-1.4400152481104	[]	[]	-2	hSpCas9	negative selection	3689292
147391126	147391149	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATACACGTGCAAGGTGCGGGG	ZIC4	ENSG00000174963	0.48850476475167814	[5]	[6,8]	9	hSpCas9	positive selection	3797895
147391163	147391186	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.08835544605652307	[6]	[7,5]	2	hSpCas9	positive selection	3797896
147391216	147391239	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCCTTCAGATGCGAGTTCGAGGG	ZIC4	ENSG00000174963	0.00733964335314341	[4]	[4,3]	0	hSpCas9	positive selection	3797897
147391216	147391239	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCCTCGAACTCGCATCTGAAGGG	ZIC4	ENSG00000174963	0.21945341797896	[4]	[5,5]	6	hSpCas9	positive selection	3797898
147391206	147391229	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGAGTTCGAGGGCTGCGAGCGG	ZIC4	ENSG00000174963	0.30079797876390607	[4]	[6,5]	8	hSpCas9	positive selection	3797899
147391126	147391149	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATACACGTGCAAGGTGCGGGG	ZIC4	ENSG00000174963	0.20264676601194273	[6]	[6,5]	5	hSpCas9	positive selection	3906502
147391163	147391186	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-0.05536684805895373	[6]	[5,5]	-1	hSpCas9	positive selection	3906503
147391216	147391239	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCCTTCAGATGCGAGTTCGAGGG	ZIC4	ENSG00000174963	-0.11796096213138973	[4]	[3,3]	-2	hSpCas9	positive selection	3906504
147391216	147391239	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCCTCGAACTCGCATCTGAAGGG	ZIC4	ENSG00000174963	0.46697654204773864	[4]	[5,5]	9	hSpCas9	positive selection	3906505
147391206	147391229	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGAGTTCGAGGGCTGCGAGCGG	ZIC4	ENSG00000174963	0.18911197989956582	[6]	[5,6]	4	hSpCas9	positive selection	3906506
147391215	147391238	3	+	26780180	A375	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.802550793228534	[]	[]	3	hSpCas9	negative selection	4014611
147390930	147390953	3	-	26780180	A375	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.550766299142378	[]	[]	1	hSpCas9	negative selection	4014612
147391215	147391238	3	+	26780180	HT29	viability (GeCKOv2 library)	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.57592287123053	[]	[]	2	hSpCas9	negative selection	4122577
147390930	147390953	3	-	26780180	HT29	viability (GeCKOv2 library)	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.610112333341484	[]	[]	2	hSpCas9	negative selection	4122578
147390930	147390953	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.1796500665303277	[4]	[3,3]	4	hSpCas9	positive selection	4183820
147390930	147390953	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	1.382008665487089	[4]	[4,4,5,5]	9	hSpCas9	positive selection	4247842
147390930	147390953	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.08983778407460324	[1]	[2,0]	1	hSpCas9	positive selection	4308948
147391215	147391238	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	-0.05852310740365399	[3]	[3,1]	-1	hSpCas9	positive selection	4308949
147391034	147391056	3	+	27760321	OCIAML3	viability	CCGAATCGTAGCCAGAGCTGGG	ZIC4	ENSG00000174963	0.20604187216173986	[776,595]	[618,608]	2	hSpCas9	negative selection	4455783
147391068	147391090	3	-	27760321	OCIAML3	viability	TAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.1142472758093952	[319,263]	[163,269]	-1	hSpCas9	negative selection	4455784
147391127	147391149	3	+	27760321	OCIAML3	viability	CCCGCACCTTGCACGTGTATGG	ZIC4	ENSG00000174963	0.3570942894934246	[1456,1164]	[1091,1583]	4	hSpCas9	negative selection	4455785
147391164	147391186	3	+	27760321	OCIAML3	viability	CACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-1.0602648286602228	[247,232]	[91,87]	-7	hSpCas9	negative selection	4455786
147391216	147391238	3	+	27760321	OCIAML3	viability	CCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.7084544880929888	[711,559]	[701,944]	8	hSpCas9	negative selection	4455787
147391034	147391056	3	+	27760321	OCIAML2	viability	CCGAATCGTAGCCAGAGCTGGG	ZIC4	ENSG00000174963	-0.08733209913413809	[776,595]	[444,615]	-1	hSpCas9	negative selection	4539246
147391068	147391090	3	-	27760321	OCIAML2	viability	TAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.057872969839489974	[319,263]	[158,313]	0	hSpCas9	negative selection	4539247
147391127	147391149	3	+	27760321	OCIAML2	viability	CCCGCACCTTGCACGTGTATGG	ZIC4	ENSG00000174963	0.4918904910624273	[1456,1164]	[1338,1671]	6	hSpCas9	negative selection	4539248
147391164	147391186	3	+	27760321	OCIAML2	viability	CACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-0.012594718691917195	[247,232]	[129,275]	0	hSpCas9	negative selection	4539249
147391216	147391238	3	+	27760321	OCIAML2	viability	CCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.8081735190040684	[711,559]	[768,1060]	9	hSpCas9	negative selection	4539250
147391034	147391056	3	+	27760321	MV411	viability	CCGAATCGTAGCCAGAGCTGGG	ZIC4	ENSG00000174963	0.32738981906071474	[776,595]	[733,308]	2	hSpCas9	negative selection	4622709
147391068	147391090	3	-	27760321	MV411	viability	TAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.7967039183744944	[319,263]	[129,80]	-5	hSpCas9	negative selection	4622710
147391127	147391149	3	+	27760321	MV411	viability	CCCGCACCTTGCACGTGTATGG	ZIC4	ENSG00000174963	0.8327559820554327	[1456,1164]	[1343,1813]	6	hSpCas9	negative selection	4622711
147391164	147391186	3	+	27760321	MV411	viability	CACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.8440628730048535	[247,232]	[163,466]	6	hSpCas9	negative selection	4622712
147391216	147391238	3	+	27760321	MV411	viability	CCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	1.7326064624466162	[711,559]	[744,2347]	9	hSpCas9	negative selection	4622713
147391034	147391056	3	+	27760321	HL60	viability	CCGAATCGTAGCCAGAGCTGGG	ZIC4	ENSG00000174963	0.3880904635871768	[776,595]	[772,680]	5	hSpCas9	negative selection	4706172
147391068	147391090	3	-	27760321	HL60	viability	TAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.40023585450479415	[319,263]	[241,388]	5	hSpCas9	negative selection	4706173
147391127	147391149	3	+	27760321	HL60	viability	CCCGCACCTTGCACGTGTATGG	ZIC4	ENSG00000174963	0.2724928913930058	[1456,1164]	[1152,1426]	3	hSpCas9	negative selection	4706174
147391164	147391186	3	+	27760321	HL60	viability	CACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-0.3212438430563742	[247,232]	[135,179]	-4	hSpCas9	negative selection	4706175
147391216	147391238	3	+	27760321	HL60	viability	CCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.4067255010762352	[711,559]	[658,710]	5	hSpCas9	negative selection	4706176
147391034	147391056	3	+	27760321	HT1080	viability	CCGAATCGTAGCCAGAGCTGGG	ZIC4	ENSG00000174963	0.39351636103790444	[595,464]	[342,205]	2	hSpCas9	negative selection	4789635
147391068	147391090	3	-	27760321	HT1080	viability	TAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-1.683956124842314	[263,205]	[31,25]	-6	hSpCas9	negative selection	4789636
147391127	147391149	3	+	27760321	HT1080	viability	CCCGCACCTTGCACGTGTATGG	ZIC4	ENSG00000174963	1.5125876174666384	[1164,908]	[960,1416]	8	hSpCas9	negative selection	4789637
147391164	147391186	3	+	27760321	HT1080	viability	CACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	2.0594925432825453	[232,181]	[377,307]	9	hSpCas9	negative selection	4789638
147391216	147391238	3	+	27760321	HT1080	viability	CCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	-0.08605412916930377	[559,436]	[209,161]	0	hSpCas9	negative selection	4789639
147391034	147391056	3	+	27760321	HT29	viability after 7 days	CCGAATCGTAGCCAGAGCTGGG	ZIC4	ENSG00000174963	0.04370616933225768	[595,464]	[766,735,616]	0	hSpCas9	negative selection	4873098
147391068	147391090	3	-	27760321	HT29	viability after 7 days	TAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.09224316596034854	[263,205]	[273,332,350]	1	hSpCas9	negative selection	4873099
147391127	147391149	3	+	27760321	HT29	viability after 7 days	CCCGCACCTTGCACGTGTATGG	ZIC4	ENSG00000174963	0.6773508636666115	[1164,908]	[2652,1884,1935]	8	hSpCas9	negative selection	4873100
147391164	147391186	3	+	27760321	HT29	viability after 7 days	CACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.2298112083264232	[232,181]	[584,143,249]	3	hSpCas9	negative selection	4873101
147391216	147391238	3	+	27760321	HT29	viability after 7 days	CCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.5328056019894227	[559,436]	[1192,815,812]	7	hSpCas9	negative selection	4873102
147391034	147391056	3	+	27760321	HT29	viability after 25 days	CCGAATCGTAGCCAGAGCTGGG	ZIC4	ENSG00000174963	0.2165048907991921	[595,464]	[698,480,958]	2	hSpCas9	negative selection	4956561
147391068	147391090	3	-	27760321	HT29	viability after 25 days	TAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.18021847128156254	[263,205]	[176,252,289]	-2	hSpCas9	negative selection	4956562
147391127	147391149	3	+	27760321	HT29	viability after 25 days	CCCGCACCTTGCACGTGTATGG	ZIC4	ENSG00000174963	0.9332695113846279	[1164,908]	[2270,2071,2462]	9	hSpCas9	negative selection	4956563
147391164	147391186	3	+	27760321	HT29	viability after 25 days	CACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-0.4087540577736105	[232,181]	[178,122,239]	-4	hSpCas9	negative selection	4956564
147391216	147391238	3	+	27760321	HT29	viability after 25 days	CCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.40349997852719327	[559,436]	[748,849,649]	4	hSpCas9	negative selection	4956565
147391034	147391056	3	+	27760321	HT29	viability after 22 days	CCGAATCGTAGCCAGAGCTGGG	ZIC4	ENSG00000174963	0.2877252051204102	[595,464]	[770,542,932]	3	hSpCas9	negative selection	5040024
147391068	147391090	3	-	27760321	HT29	viability after 22 days	TAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.6609640979805573	[263,205]	[125,185,204]	-5	hSpCas9	negative selection	5040025
147391127	147391149	3	+	27760321	HT29	viability after 22 days	CCCGCACCTTGCACGTGTATGG	ZIC4	ENSG00000174963	0.8176722040413906	[1164,908]	[2073,2137,2127]	8	hSpCas9	negative selection	5040026
147391164	147391186	3	+	27760321	HT29	viability after 22 days	CACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.07520234241290424	[232,181]	[224,168,365]	0	hSpCas9	negative selection	5040027
147391216	147391238	3	+	27760321	HT29	viability after 22 days	CCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.49679461513666295	[559,436]	[865,767,803]	5	hSpCas9	negative selection	5040028
147391034	147391056	3	+	27760321	HT29	viability after 19 days	CCGAATCGTAGCCAGAGCTGGG	ZIC4	ENSG00000174963	-0.08730969247041254	[595,464]	[737,358,630]	-1	hSpCas9	negative selection	5123487
147391068	147391090	3	-	27760321	HT29	viability after 19 days	TAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.3126592603281025	[263,205]	[435,325,252]	3	hSpCas9	negative selection	5123488
147391127	147391149	3	+	27760321	HT29	viability after 19 days	CCCGCACCTTGCACGTGTATGG	ZIC4	ENSG00000174963	0.9669259890200916	[1164,908]	[2122,2154,2641]	8	hSpCas9	negative selection	5123489
147391164	147391186	3	+	27760321	HT29	viability after 19 days	CACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.1932895488890244	[232,181]	[245,180,379]	1	hSpCas9	negative selection	5123490
147391216	147391238	3	+	27760321	HT29	viability after 19 days	CCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.7525642249463786	[559,436]	[1079,1162,661]	7	hSpCas9	negative selection	5123491
147391034	147391056	3	+	27760321	HT29	viability after 16 days	CCGAATCGTAGCCAGAGCTGGG	ZIC4	ENSG00000174963	0.2791905502063513	[595,464]	[896,539,744]	3	hSpCas9	negative selection	5206950
147391068	147391090	3	-	27760321	HT29	viability after 16 days	TAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.4615204073077914	[263,205]	[195,123,254]	-5	hSpCas9	negative selection	5206951
147391127	147391149	3	+	27760321	HT29	viability after 16 days	CCCGCACCTTGCACGTGTATGG	ZIC4	ENSG00000174963	1.054878813531673	[1164,908]	[2524,2579,2131]	9	hSpCas9	negative selection	5206952
147391164	147391186	3	+	27760321	HT29	viability after 16 days	CACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-0.3024414096467035	[232,181]	[248,129,192]	-3	hSpCas9	negative selection	5206953
147391216	147391238	3	+	27760321	HT29	viability after 16 days	CCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.6520889666229763	[559,436]	[1128,990,529]	7	hSpCas9	negative selection	5206954
147391034	147391056	3	+	27760321	HT29	viability after 13 days	CCGAATCGTAGCCAGAGCTGGG	ZIC4	ENSG00000174963	0.18291366272070153	[595,464]	[669,713,710]	2	hSpCas9	negative selection	5290413
147391068	147391090	3	-	27760321	HT29	viability after 13 days	TAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.06444491452280199	[263,205]	[303,314,238]	0	hSpCas9	negative selection	5290414
147391127	147391149	3	+	27760321	HT29	viability after 13 days	CCCGCACCTTGCACGTGTATGG	ZIC4	ENSG00000174963	0.6577430960224875	[1164,908]	[1729,2002,1956]	8	hSpCas9	negative selection	5290415
147391164	147391186	3	+	27760321	HT29	viability after 13 days	CACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-0.12926475865828269	[232,181]	[174,292,193]	-1	hSpCas9	negative selection	5290416
147391216	147391238	3	+	27760321	HT29	viability after 13 days	CCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.4822061697466445	[559,436]	[931,818,679]	6	hSpCas9	negative selection	5290417
147391034	147391056	3	+	27760321	HT29	viability after 10 days	CCGAATCGTAGCCAGAGCTGGG	ZIC4	ENSG00000174963	-0.03884730612104692	[595,464]	[539,748,647]	0	hSpCas9	negative selection	5373876
147391068	147391090	3	-	27760321	HT29	viability after 10 days	TAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.3428252908822409	[263,205]	[338,202,152]	-4	hSpCas9	negative selection	5373877
147391127	147391149	3	+	27760321	HT29	viability after 10 days	CCCGCACCTTGCACGTGTATGG	ZIC4	ENSG00000174963	0.6291046331873116	[1164,908]	[1734,2342,1939]	8	hSpCas9	negative selection	5373878
147391164	147391186	3	+	27760321	HT29	viability after 10 days	CACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-0.4189826840356029	[232,181]	[265,174,140]	-5	hSpCas9	negative selection	5373879
147391216	147391238	3	+	27760321	HT29	viability after 10 days	CCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.562094045717457	[559,436]	[900,954,901]	7	hSpCas9	negative selection	5373880
147391034	147391056	3	+	27760321	MOLM13	viability	CCGAATCGTAGCCAGAGCTGGG	ZIC4	ENSG00000174963	1.292447416233924	[776,595]	[664,1176]	8	hSpCas9	negative selection	5457339
147391068	147391090	3	-	27760321	MOLM13	viability	TAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-1.9090616758231524	[319,263]	[27,56]	-8	hSpCas9	negative selection	5457340
147391127	147391149	3	+	27760321	MOLM13	viability	CCCGCACCTTGCACGTGTATGG	ZIC4	ENSG00000174963	1.1661427600399015	[1456,1164]	[1674,1628]	7	hSpCas9	negative selection	5457341
147391164	147391186	3	+	27760321	MOLM13	viability	CACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-0.31346066700786857	[247,232]	[145,77]	-2	hSpCas9	negative selection	5457342
147391216	147391238	3	+	27760321	MOLM13	viability	CCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	2.0054875424783383	[711,559]	[1432,1429]	9	hSpCas9	negative selection	5457343
147392299	147392322	3	+	27661255	K562	viability	GGCTGGCATAGGCCGGGGAGGGG	ZIC4	ENSG00000174963	-0.5110793443145384	[1055,981]	[633,518]	-7	dCas9-KRAB	negative selection	5524103
147391975	147391998	3	-	27661255	K562	viability	GTATCTGGAGGGATCCCGGAAGG	ZIC4	ENSG00000174963	0.036571380428766675	[1137,885]	[915,761]	1	dCas9-KRAB	negative selection	5524104
147390930	147390953	3	-	27260156	BXPC3	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.6034937853225449	[176]	[250,245,329,304]	9	hSpCas9	negative selection	5581408
147391215	147391238	3	+	27260156	BXPC3	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.061796922303708854	[493]	[410,579,544,640]	1	hSpCas9	negative selection	5581409
147390930	147390953	3	-	27260156	A673	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.21671336821699794	[176]	[259,267,237,220]	5	hSpCas9	negative selection	5702659
147391215	147391238	3	+	27260156	A673	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.16657649246173	[493]	[828,545,582,729]	4	hSpCas9	negative selection	5702660
147390930	147390953	3	-	27260156	A375	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.8266515431988916	[176]	[426,438,365,256]	9	hSpCas9	negative selection	5823910
147391215	147391238	3	+	27260156	A375	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.6148802463075762	[493]	[708,983,932,913]	8	hSpCas9	negative selection	5823911
147390930	147390953	3	-	27260156	COLO741	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.5764808031669522	[176]	[319,288,395]	9	hSpCas9	negative selection	5945161
147391215	147391238	3	+	27260156	COLO741	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.10896535068848183	[493]	[589,788,655]	2	hSpCas9	negative selection	5945162
147390930	147390953	3	-	27260156	CAL120	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.522762640799825	[176]	[197,283,446]	7	hSpCas9	negative selection	6066412
147391215	147391238	3	+	27260156	CAL120	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.7896693053869649	[493]	[1257,1122,839]	9	hSpCas9	negative selection	6066413
147390930	147390953	3	-	27260156	CADOES1	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.5331135393241732	[176]	[252,179,247,272]	8	hSpCas9	negative selection	6187663
147391215	147391238	3	+	27260156	CADOES1	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.5807953162524923	[493]	[794,640,634,676]	8	hSpCas9	negative selection	6187664
147390930	147390953	3	-	27260156	EWS502	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.12659892020578867	[176]	[164,220,173,265]	2	hSpCas9	negative selection	6308914
147391215	147391238	3	+	27260156	EWS502	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.34864548112936555	[493]	[678,732,658,580]	6	hSpCas9	negative selection	6308915
147390930	147390953	3	-	27260156	EW8	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.7561373017113407	[176]	[231,337,169,239]	9	hSpCas9	negative selection	6430165
147391215	147391238	3	+	27260156	EW8	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.2176473539950945	[493]	[452,535,416,461]	4	hSpCas9	negative selection	6430166
147390930	147390953	3	-	27260156	CORL105	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.4200323669614453	[176]	[252,212,358,296]	7	hSpCas9	negative selection	6551416
147391215	147391238	3	+	27260156	CORL105	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.2995449194656414	[493]	[648,713,921,592]	5	hSpCas9	negative selection	6551417
147390930	147390953	3	-	27260156	HS294T	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.9619299510794856	[176]	[105,57,105,294]	9	hSpCas9	negative selection	6672667
147391215	147391238	3	+	27260156	HS294T	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.46204564753463007	[493]	[220,242,240,368]	6	hSpCas9	negative selection	6672668
147390930	147390953	3	-	27260156	HCC44	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.45691532086433806	[176]	[252,252,301,293]	7	hSpCas9	negative selection	6793918
147391215	147391238	3	+	27260156	HCC44	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.43532014173155387	[493]	[724,732,942,650]	7	hSpCas9	negative selection	6793919
147390930	147390953	3	-	27260156	G402	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.6475585436821167	[176]	[419,562,206,193]	7	hSpCas9	negative selection	6915169
147391215	147391238	3	+	27260156	G402	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.47408421604742845	[493]	[509,1356,691,772]	6	hSpCas9	negative selection	6915170
147390930	147390953	3	-	27260156	L33	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.467280506355253	[176]	[252,102,187,175]	8	hSpCas9	negative selection	7036420
147391215	147391238	3	+	27260156	L33	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.3908526646003367	[493]	[609,319,371,608]	7	hSpCas9	negative selection	7036421
147390930	147390953	3	-	27260156	K562	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	1.1431803798215847	[176]	[281,463,170,456]	9	hSpCas9	negative selection	7157671
147391215	147391238	3	+	27260156	K562	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.3548330378166112	[493]	[557,337,646,671]	4	hSpCas9	negative selection	7157672
147390930	147390953	3	-	27260156	HT29	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.1662110673023427	[176]	[218,279,237,229]	3	hSpCas9	negative selection	7278922
147391215	147391238	3	+	27260156	HT29	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.3454791032274896	[493]	[756,918,464,900]	6	hSpCas9	negative selection	7278923
147390930	147390953	3	-	27260156	MHHES1	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.619964118952556	[176]	[376,235,387,235]	9	hSpCas9	negative selection	7400173
147391215	147391238	3	+	27260156	MHHES1	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.33627932647296044	[493]	[700,695,766,642]	6	hSpCas9	negative selection	7400174
147390930	147390953	3	-	27260156	MEWO	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.5418214371368912	[176]	[295,201,235]	9	hSpCas9	negative selection	7521424
147391215	147391238	3	+	27260156	MEWO	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.23915696944629267	[493]	[681,507,472]	5	hSpCas9	negative selection	7521425
147390930	147390953	3	-	27260156	LNCAPCLONEFGC	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.4703548749089339	[176]	[182,285,262,158]	7	hSpCas9	negative selection	7642675
147391215	147391238	3	+	27260156	LNCAPCLONEFGC	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.5290721672392542	[493]	[624,508,753,719]	8	hSpCas9	negative selection	7642676
147390930	147390953	3	-	27260156	PANC0327	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.8626161911671915	[176]	[334,220,332,266]	9	hSpCas9	negative selection	7763926
147391215	147391238	3	+	27260156	PANC0327	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.10749441184616089	[493]	[625,323,604,367]	1	hSpCas9	negative selection	7763927
147390930	147390953	3	-	27260156	NCIH2009	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.9233763557555195	[176]	[523,639,249]	9	hSpCas9	negative selection	7885177
147391215	147391238	3	+	27260156	NCIH2009	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.367499994470529	[493]	[988,849,850]	5	hSpCas9	negative selection	7885178
147390930	147390953	3	-	27260156	NCIH1373	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.6533136011603585	[176]	[335,248,505,39]	6	hSpCas9	negative selection	8006428
147391215	147391238	3	+	27260156	NCIH1373	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.4811266322427189	[493]	[962,765,552,221]	5	hSpCas9	negative selection	8006429
147390930	147390953	3	-	27260156	PATU8902	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.5549196125236652	[176]	[142,400,401,509]	6	hSpCas9	negative selection	8127679
147391215	147391238	3	+	27260156	PATU8902	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.4986867203446891	[493]	[1432,983,494,1101]	5	hSpCas9	negative selection	8127680
147390930	147390953	3	-	27260156	PANC1	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.5216582327220892	[176]	[283,183,157,231]	8	hSpCas9	negative selection	8248930
147391215	147391238	3	+	27260156	PANC1	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.2995141171683073	[493]	[385,615,619,486]	5	hSpCas9	negative selection	8248931
147390930	147390953	3	-	27260156	PANC0813	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.7450227229168329	[176]	[307,382,186,501]	9	hSpCas9	negative selection	8370181
147391215	147391238	3	+	27260156	PANC0813	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.31685361545182367	[493]	[644,998,555,683]	5	hSpCas9	negative selection	8370182
147390930	147390953	3	-	27260156	RDES	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.6147474931097257	[176]	[255,359,267,366]	8	hSpCas9	negative selection	8491432
147391215	147391238	3	+	27260156	RDES	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.4928162935545157	[493]	[738,855,736,851]	7	hSpCas9	negative selection	8491433
147390930	147390953	3	-	27260156	PC3	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.6363822323063112	[176]	[189,303,485,201]	9	hSpCas9	negative selection	8612683
147391215	147391238	3	+	27260156	PC3	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.2951092033110276	[493]	[370,353,1240,766]	6	hSpCas9	negative selection	8612684
147390930	147390953	3	-	27260156	PATU8988T	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.47841386227281835	[176]	[311,208,230,194]	7	hSpCas9	negative selection	8733934
147391215	147391238	3	+	27260156	PATU8988T	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.19188831610984558	[493]	[446,428,728,563]	3	hSpCas9	negative selection	8733935
147390930	147390953	3	-	27260156	T47D	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.5119161559321914	[176]	[342,243,248,346]	9	hSpCas9	negative selection	8855185
147391215	147391238	3	+	27260156	T47D	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.24907006321131586	[493]	[736,562,722,723]	5	hSpCas9	negative selection	8855186
147390930	147390953	3	-	27260156	SU8686	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.17485201172369802	[176]	[221,152,200,221]	3	hSpCas9	negative selection	8976436
147391215	147391238	3	+	27260156	SU8686	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.532105451525298	[493]	[743,544,762,810]	8	hSpCas9	negative selection	8976437
147390930	147390953	3	-	27260156	SKES1	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.5111940739351939	[176]	[322,312,168,220]	8	hSpCas9	negative selection	9097687
147391215	147391238	3	+	27260156	SKES1	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.10508817587206047	[493]	[624,496,457,542]	2	hSpCas9	negative selection	9097688
147390930	147390953	3	-	27260156	TOV112D	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.8779955683578334	[176]	[209,426,361,318]	9	hSpCas9	negative selection	9218938
147391215	147391238	3	+	27260156	TOV112D	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.16631222378888338	[493]	[753,585,447,458]	3	hSpCas9	negative selection	9218939
147390930	147390953	3	-	27260156	TC71	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.28877541291007813	[176]	[224,257,161,287]	7	hSpCas9	negative selection	9340189
147391215	147391238	3	+	27260156	TC71	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.050040848961795364	[493]	[495,513,545,643]	1	hSpCas9	negative selection	9340190
147390930	147390953	3	-	27260156	TC32	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.7396535882102568	[176]	[317,212,258,321]	9	hSpCas9	negative selection	9461440
147391215	147391238	3	+	27260156	TC32	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.32360000645400405	[493]	[613,348,758,688]	6	hSpCas9	negative selection	9461441
147390988	147391011	3	+	27869803	HPAFII	viability after 27 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.27413820719215465	[463]	[336,88,NaN]	-2	hSpCas9	negative selection	9583011
147391039	147391062	3	+	27869803	HPAFII	viability after 27 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	0.6921257657908466	[194]	[187,146,NaN]	5	hSpCas9	negative selection	9583012
147390988	147391011	3	+	27869803	HPAFII	viability after 15 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.27054466941908883	[463]	[635,274,NaN]	-3	hSpCas9	negative selection	9665460
147391039	147391062	3	+	27869803	HPAFII	viability after 15 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	0.2953807897199351	[194]	[316,219,NaN]	3	hSpCas9	negative selection	9665461
147390988	147391011	3	+	27869803	ASPC1	viability after 36 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	0.7020757605171835	[1059]	[745,511,565]	7	hSpCas9	negative selection	9747909
147391039	147391062	3	+	27869803	ASPC1	viability after 36 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	0.8582539606263797	[369]	[352,134,226]	8	hSpCas9	negative selection	9747910
147390988	147391011	3	+	27869803	PATU8988S	viability after 35 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	0.5599621998514378	[897]	[613,451,NaN]	6	hSpCas9	negative selection	9830358
147391039	147391062	3	+	27869803	PATU8988S	viability after 35 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-0.8460148027701129	[356]	[74,84,NaN]	-7	hSpCas9	negative selection	9830359
147390988	147391011	3	+	27869803	PATU8988S	viability after 31 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	0.45562134439466007	[897]	[538,429,NaN]	5	hSpCas9	negative selection	9912807
147391039	147391062	3	+	27869803	PATU8988S	viability after 31 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	-0.08259274638409775	[356]	[89,190,NaN]	-1	hSpCas9	negative selection	9912808
147390988	147391011	3	+	27869803	HPAFII	viability after 35 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	0.08413239076723122	[463]	[375,105,NaN]	0	hSpCas9	negative selection	9995256
147391039	147391062	3	+	27869803	HPAFII	viability after 35 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	0.5036746298437405	[194]	[186,86,NaN]	3	hSpCas9	negative selection	9995257
147390988	147391011	3	+	27869803	HPAFII	viability after 31 days	TTGTGGCCGCAGTCCGACGAGGG	ZIC4	ENSG00000174963	-0.24784779366608323	[463]	[359,65,NaN]	-2	hSpCas9	negative selection	10077705
147391039	147391062	3	+	27869803	HPAFII	viability after 31 days	TCGTAGCCAGAGCTGGGCGGCGG	ZIC4	ENSG00000174963	0.6900906291420617	[194]	[177,174,NaN]	5	hSpCas9	negative selection	10077706
147391036	147391059	3	+	28162770	P31FUJ	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.9512570812315699	[157]	[358]	9	hSpCas9	negative selection	10268574
147391163	147391186	3	+	28162770	P31FUJ	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.7839735083364482	[341]	[691]	8	hSpCas9	negative selection	10268575
147390987	147391010	3	+	28162770	P31FUJ	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	0.518699482909708	[236]	[398]	6	hSpCas9	negative selection	10268576
147390965	147390988	3	-	28162770	P31FUJ	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-1.2652236821067562	[314]	[153]	-7	hSpCas9	negative selection	10268577
147390930	147390953	3	-	28162770	P31FUJ	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	1.1539939906502186	[186]	[488]	9	hSpCas9	negative selection	10268578
147391127	147391150	3	-	28162770	P31FUJ	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	1.3004670621252845	[160]	[465]	9	hSpCas9	negative selection	10268579
147391068	147391091	3	-	28162770	P31FUJ	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.08065846906826368	[580]	[721]	0	hSpCas9	negative selection	10268580
147391006	147391029	3	+	28162770	P31FUJ	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	0.05670441278060645	[89]	[109]	0	hSpCas9	negative selection	10268581
147391215	147391238	3	+	28162770	P31FUJ	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	1.0248140134732013	[288]	[690]	9	hSpCas9	negative selection	10268582
147391036	147391059	3	+	28162770	TF1	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	NaN	[NaN]	[260]	1	hSpCas9	negative selection	10437940
147391163	147391186	3	+	28162770	TF1	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	NaN	[NaN]	[506]	1	hSpCas9	negative selection	10437941
147390987	147391010	3	+	28162770	TF1	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	NaN	[NaN]	[411]	1	hSpCas9	negative selection	10437942
147390965	147390988	3	-	28162770	TF1	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10437943
147390930	147390953	3	-	28162770	TF1	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	NaN	[NaN]	[374]	1	hSpCas9	negative selection	10437944
147391127	147391150	3	-	28162770	TF1	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	NaN	[NaN]	[213]	1	hSpCas9	negative selection	10437945
147391068	147391091	3	-	28162770	TF1	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	NaN	[NaN]	[348]	1	hSpCas9	negative selection	10437946
147391006	147391029	3	+	28162770	TF1	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10437947
147391215	147391238	3	+	28162770	TF1	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	NaN	[NaN]	[366]	1	hSpCas9	negative selection	10437948
147391036	147391059	3	+	28162770	SKM1	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.30232643698019607	[49]	[108]	3	hSpCas9	negative selection	10607306
147391163	147391186	3	+	28162770	SKM1	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.7471068514983137	[60]	[180]	7	hSpCas9	negative selection	10607307
147390987	147391010	3	+	28162770	SKM1	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	-0.29307323221517734	[69]	[100]	-2	hSpCas9	negative selection	10607308
147390965	147390988	3	-	28162770	SKM1	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-1.0443941193584534	[97]	[83]	-6	hSpCas9	negative selection	10607309
147390930	147390953	3	-	28162770	SKM1	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.883550943512739	[64]	[211]	8	hSpCas9	negative selection	10607310
147391127	147391150	3	-	28162770	SKM1	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	-0.4796095005749276	[55]	[70]	-4	hSpCas9	negative selection	10607311
147391068	147391091	3	-	28162770	SKM1	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.8325709397321929	[136]	[135]	-6	hSpCas9	negative selection	10607312
147391006	147391029	3	+	28162770	SKM1	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	1.4106590587682695	[19]	[93]	9	hSpCas9	negative selection	10607313
147391215	147391238	3	+	28162770	SKM1	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.2193390973588939	[85]	[176]	2	hSpCas9	negative selection	10607314
147391036	147391059	3	+	28162770	SKM1	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.30232643698019607	[49]	[108]	3	hSpCas9	negative selection	10776672
147391163	147391186	3	+	28162770	SKM1	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.7471068514983137	[60]	[180]	7	hSpCas9	negative selection	10776673
147390987	147391010	3	+	28162770	SKM1	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	-0.29307323221517734	[69]	[100]	-2	hSpCas9	negative selection	10776674
147390965	147390988	3	-	28162770	SKM1	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-1.0443941193584534	[97]	[83]	-6	hSpCas9	negative selection	10776675
147390930	147390953	3	-	28162770	SKM1	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.883550943512739	[64]	[211]	8	hSpCas9	negative selection	10776676
147391127	147391150	3	-	28162770	SKM1	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	-0.4796095005749276	[55]	[70]	-4	hSpCas9	negative selection	10776677
147391068	147391091	3	-	28162770	SKM1	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.8325709397321929	[136]	[135]	-6	hSpCas9	negative selection	10776678
147391006	147391029	3	+	28162770	SKM1	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	1.4106590587682695	[19]	[93]	9	hSpCas9	negative selection	10776679
147391215	147391238	3	+	28162770	SKM1	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.2193390973588939	[85]	[176]	2	hSpCas9	negative selection	10776680
147391036	147391059	3	+	28162770	PL21	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.4457919420948776	[166]	[98]	4	hSpCas9	negative selection	10946038
147391163	147391186	3	+	28162770	PL21	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	-0.17950397825432954	[254]	[97]	-1	hSpCas9	negative selection	10946039
147390987	147391010	3	+	28162770	PL21	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	0.7029834947369711	[246]	[174]	6	hSpCas9	negative selection	10946040
147390965	147390988	3	-	28162770	PL21	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-0.9153376029306157	[272]	[62]	-6	hSpCas9	negative selection	10946041
147390930	147390953	3	-	28162770	PL21	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	1.0826820329411433	[242]	[223]	8	hSpCas9	negative selection	10946042
147391127	147391150	3	-	28162770	PL21	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	1.3770173765733995	[137]	[155]	9	hSpCas9	negative selection	10946043
147391068	147391091	3	-	28162770	PL21	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.47088898545111935	[372]	[224]	4	hSpCas9	negative selection	10946044
147391006	147391029	3	+	28162770	PL21	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	-0.0343256391477027	[79]	[33]	0	hSpCas9	negative selection	10946045
147391215	147391238	3	+	28162770	PL21	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.561813888169439	[178]	[114]	5	hSpCas9	negative selection	10946046
147391036	147391059	3	+	28162770	P31FUJ	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.9512570812315699	[157]	[358]	9	hSpCas9	negative selection	11115404
147391163	147391186	3	+	28162770	P31FUJ	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.7839735083364482	[341]	[691]	8	hSpCas9	negative selection	11115405
147390987	147391010	3	+	28162770	P31FUJ	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	0.518699482909708	[236]	[398]	6	hSpCas9	negative selection	11115406
147390965	147390988	3	-	28162770	P31FUJ	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-1.2652236821067562	[314]	[153]	-7	hSpCas9	negative selection	11115407
147390930	147390953	3	-	28162770	P31FUJ	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	1.1539939906502186	[186]	[488]	9	hSpCas9	negative selection	11115408
147391127	147391150	3	-	28162770	P31FUJ	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	1.3004670621252845	[160]	[465]	9	hSpCas9	negative selection	11115409
147391068	147391091	3	-	28162770	P31FUJ	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.08065846906826368	[580]	[721]	0	hSpCas9	negative selection	11115410
147391006	147391029	3	+	28162770	P31FUJ	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	0.05670441278060645	[89]	[109]	0	hSpCas9	negative selection	11115411
147391215	147391238	3	+	28162770	P31FUJ	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	1.0248140134732013	[288]	[690]	9	hSpCas9	negative selection	11115412
147391036	147391059	3	+	28162770	OCIAML5	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	-0.24755127272144012	[170]	[259]	-2	hSpCas9	negative selection	11284770
147391163	147391186	3	+	28162770	OCIAML5	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	1.0688308827384008	[163]	[620]	8	hSpCas9	negative selection	11284771
147390987	147391010	3	+	28162770	OCIAML5	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	0.5500318727073488	[111]	[295]	5	hSpCas9	negative selection	11284772
147390965	147390988	3	-	28162770	OCIAML5	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-2.0767728580386917	[207]	[88]	-8	hSpCas9	negative selection	11284773
147390930	147390953	3	-	28162770	OCIAML5	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.8708961639032347	[175]	[580]	7	hSpCas9	negative selection	11284774
147391127	147391150	3	-	28162770	OCIAML5	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	1.2062975916499916	[108]	[453]	8	hSpCas9	negative selection	11284775
147391068	147391091	3	-	28162770	OCIAML5	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.3791632137316283	[278]	[654]	3	hSpCas9	negative selection	11284776
147391006	147391029	3	+	28162770	OCIAML5	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	-0.2601513095010739	[68]	[103]	-2	hSpCas9	negative selection	11284777
147391215	147391238	3	+	28162770	OCIAML5	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.5828704858525517	[215]	[583]	5	hSpCas9	negative selection	11284778
147391036	147391059	3	+	28162770	EOL1	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.48748396596169175	[351]	[259]	4	hSpCas9	negative selection	11454136
147391163	147391186	3	+	28162770	EOL1	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.08618616182788624	[387]	[216]	0	hSpCas9	negative selection	11454137
147390987	147391010	3	+	28162770	EOL1	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	0.6500784706744573	[455]	[376]	6	hSpCas9	negative selection	11454138
147390965	147390988	3	-	28162770	EOL1	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-0.9804557144937185	[572]	[152]	-6	hSpCas9	negative selection	11454139
147390930	147390953	3	-	28162770	EOL1	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.5257204994729497	[471]	[357]	5	hSpCas9	negative selection	11454140
147391127	147391150	3	-	28162770	EOL1	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	1.1072668852288996	[236]	[268]	8	hSpCas9	negative selection	11454141
147391068	147391091	3	-	28162770	EOL1	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.3104722580936625	[611]	[259]	-2	hSpCas9	negative selection	11454142
147391006	147391029	3	+	28162770	EOL1	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	0.3923267329213518	[93]	[64]	3	hSpCas9	negative selection	11454143
147391215	147391238	3	+	28162770	EOL1	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	-0.005550215199309136	[281]	[147]	0	hSpCas9	negative selection	11454144
147391036	147391059	3	+	28162770	MOLM13	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.8894935514272649	[273]	[366]	6	hSpCas9	negative selection	11623502
147391163	147391186	3	+	28162770	MOLM13	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.9924572842135663	[373]	[537]	7	hSpCas9	negative selection	11623503
147390987	147391010	3	+	28162770	MOLM13	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	1.472335286575771	[323]	[649]	9	hSpCas9	negative selection	11623504
147390965	147390988	3	-	28162770	MOLM13	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-0.4034684670163165	[385]	[210]	-2	hSpCas9	negative selection	11623505
147390930	147390953	3	-	28162770	MOLM13	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.8709771243667107	[393]	[520]	6	hSpCas9	negative selection	11623506
147391127	147391150	3	-	28162770	MOLM13	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	0.7716701297216818	[191]	[236]	6	hSpCas9	negative selection	11623507
147391068	147391091	3	-	28162770	MOLM13	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.6266736199884012	[661]	[309]	-4	hSpCas9	negative selection	11623508
147391006	147391029	3	+	28162770	MOLM13	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	-0.3043047009326091	[151]	[88]	-2	hSpCas9	negative selection	11623509
147391215	147391238	3	+	28162770	MOLM13	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.027779860308902227	[444]	[327]	0	hSpCas9	negative selection	11623510
147391036	147391059	3	+	28162770	HEL	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.43364323327736676	[251]	[217]	3	hSpCas9	negative selection	11792868
147391163	147391186	3	+	28162770	HEL	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.4651521288499779	[353]	[312]	4	hSpCas9	negative selection	11792869
147390987	147391010	3	+	28162770	HEL	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	1.7396843880855637	[222]	[476]	9	hSpCas9	negative selection	11792870
147390965	147390988	3	-	28162770	HEL	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-2.3233138360763053	[335]	[42]	-8	hSpCas9	negative selection	11792871
147390930	147390953	3	-	28162770	HEL	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	1.508162810313491	[319]	[582]	9	hSpCas9	negative selection	11792872
147391127	147391150	3	-	28162770	HEL	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	0.8977804470806202	[180]	[215]	7	hSpCas9	negative selection	11792873
147391068	147391091	3	-	28162770	HEL	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.24881444054133273	[537]	[289]	-2	hSpCas9	negative selection	11792874
147391006	147391029	3	+	28162770	HEL	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	0.591513508645184	[85]	[82]	5	hSpCas9	negative selection	11792875
147391215	147391238	3	+	28162770	HEL	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.9508611273626888	[314]	[389]	8	hSpCas9	negative selection	11792876
147391036	147391059	3	+	28162770	MV411	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.3164791952124266	[203]	[213]	3	hSpCas9	negative selection	11962234
147391163	147391186	3	+	28162770	MV411	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	1.2642719896460355	[212]	[430]	9	hSpCas9	negative selection	11962235
147390987	147391010	3	+	28162770	MV411	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	0.6567613988672256	[252]	[335]	6	hSpCas9	negative selection	11962236
147390965	147390988	3	-	28162770	MV411	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-1.3196030419411184	[239]	[80]	-7	hSpCas9	negative selection	11962237
147390930	147390953	3	-	28162770	MV411	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.8480816737362012	[243]	[369]	7	hSpCas9	negative selection	11962238
147391127	147391150	3	-	28162770	MV411	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	0.8369727812937555	[104]	[157]	7	hSpCas9	negative selection	11962239
147391068	147391091	3	-	28162770	MV411	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.4595105420409913	[460]	[533]	4	hSpCas9	negative selection	11962240
147391006	147391029	3	+	28162770	MV411	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	1.2701576272828587	[62]	[127]	9	hSpCas9	negative selection	11962241
147391215	147391238	3	+	28162770	MV411	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	1.2049328222682398	[154]	[300]	9	hSpCas9	negative selection	11962242
147391036	147391059	3	+	28162770	MONOMAC1	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	-0.41307377335617795	[150]	[129]	-4	hSpCas9	negative selection	12131600
147391163	147391186	3	+	28162770	MONOMAC1	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.6227551782362731	[131]	[232]	6	hSpCas9	negative selection	12131601
147390987	147391010	3	+	28162770	MONOMAC1	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	0.9219042256639536	[127]	[277]	8	hSpCas9	negative selection	12131602
147390965	147390988	3	-	28162770	MONOMAC1	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-1.6864216877984788	[218]	[77]	-8	hSpCas9	negative selection	12131603
147390930	147390953	3	-	28162770	MONOMAC1	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.00342773534214158	[160]	[184]	0	hSpCas9	negative selection	12131604
147391127	147391150	3	-	28162770	MONOMAC1	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	-0.4170025310014617	[98]	[84]	-4	hSpCas9	negative selection	12131605
147391068	147391091	3	-	28162770	MONOMAC1	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.25997292269460615	[270]	[371]	2	hSpCas9	negative selection	12131606
147391006	147391029	3	+	28162770	MONOMAC1	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	-1.0271118456172417	[63]	[35]	-7	hSpCas9	negative selection	12131607
147391215	147391238	3	+	28162770	MONOMAC1	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	1.5477060976983716	[110]	[371]	9	hSpCas9	negative selection	12131608
147391036	147391059	3	+	28162770	OCIAML2	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.07464897400651282	[42]	[250]	0	hSpCas9	negative selection	12300966
147391163	147391186	3	+	28162770	OCIAML2	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	1.1072432506926757	[33]	[405]	9	hSpCas9	negative selection	12300967
147390987	147391010	3	+	28162770	OCIAML2	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	0.6660327220684027	[38]	[342]	6	hSpCas9	negative selection	12300968
147390965	147390988	3	-	28162770	OCIAML2	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-1.4568240257171308	[51]	[104]	-7	hSpCas9	negative selection	12300969
147390930	147390953	3	-	28162770	OCIAML2	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.6254667643419821	[48]	[418]	6	hSpCas9	negative selection	12300970
147391127	147391150	3	-	28162770	OCIAML2	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	0.06186525558485939	[27]	[161]	0	hSpCas9	negative selection	12300971
147391068	147391091	3	-	28162770	OCIAML2	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	0.03286857485009875	[84]	[481]	0	hSpCas9	negative selection	12300972
147391006	147391029	3	+	28162770	OCIAML2	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	0.27660410437787203	[20]	[140]	2	hSpCas9	negative selection	12300973
147391215	147391238	3	+	28162770	OCIAML2	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.6698513983076693	[32]	[290]	6	hSpCas9	negative selection	12300974
147391036	147391059	3	+	28162770	OCIAML3	viability	GAATCGTAGCCAGAGCTGGGCGG	ZIC4	ENSG00000174963	0.25244710142238125	[51]	[186]	2	hSpCas9	negative selection	12470332
147391163	147391186	3	+	28162770	OCIAML3	viability	GCACGTGCGAATGCTTCTTACGG	ZIC4	ENSG00000174963	0.4725599766148265	[89]	[376]	4	hSpCas9	negative selection	12470333
147390987	147391010	3	+	28162770	OCIAML3	viability	CTTGTGGCCGCAGTCCGACGAGG	ZIC4	ENSG00000174963	3.940835597596123	[71]	[3337]	9	hSpCas9	negative selection	12470334
147390965	147390988	3	-	28162770	OCIAML3	viability	GTCCCAGGTGGCCTCCTCGGCGG	ZIC4	ENSG00000174963	-0.4692011845878825	[82]	[180]	-4	hSpCas9	negative selection	12470335
147390930	147390953	3	-	28162770	OCIAML3	viability	GTACCGCCGACTTGAGCGAATGG	ZIC4	ENSG00000174963	0.18452444656768718	[64]	[222]	1	hSpCas9	negative selection	12470336
147391127	147391150	3	-	28162770	OCIAML3	viability	GCCATACACGTGCAAGGTGCGGG	ZIC4	ENSG00000174963	0.31928072648250616	[29]	[112]	3	hSpCas9	negative selection	12470337
147391068	147391091	3	-	28162770	OCIAML3	viability	GTAAGCACATGAAGGTGCACGGG	ZIC4	ENSG00000174963	-0.31983267688516903	[128]	[311]	-2	hSpCas9	negative selection	12470338
147391006	147391029	3	+	28162770	OCIAML3	viability	GAGGGCGACACGAGGGCAGACGG	ZIC4	ENSG00000174963	-1.478530422904227	[23]	[25]	-7	hSpCas9	negative selection	12470339
147391215	147391238	3	+	28162770	OCIAML3	viability	GCCCTCGAACTCGCATCTGAAGG	ZIC4	ENSG00000174963	0.7069463254694576	[96]	[477]	6	hSpCas9	negative selection	12470340