| 44228523 | 44228546 | 19 | + | 26472758 | Jiyoye | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.995361783101316 | [297] | [447] | 6 | hSpCas9 | negative selection | 186257 | 44217817 | 44217840 | 19 | - | 26472758 | Jiyoye | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | -0.32862627952669676 | [412] | [247] | -2 | hSpCas9 | negative selection | 186258 | 44228498 | 44228521 | 19 | + | 26472758 | Jiyoye | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 1.4548721235371698 | [118] | [245] | 8 | hSpCas9 | negative selection | 186259 | 44228469 | 44228492 | 19 | + | 26472758 | Jiyoye | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | 0.2551722880608236 | [139] | [125] | 2 | hSpCas9 | negative selection | 186260 | 44228550 | 44228573 | 19 | + | 26472758 | Jiyoye | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | 0.48847548360772164 | [68] | [72] | 3 | hSpCas9 | negative selection | 186261 | 44217796 | 44217819 | 19 | - | 26472758 | Jiyoye | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | -0.4478762825830269 | [245] | [135] | -3 | hSpCas9 | negative selection | 186262 | 44228483 | 44228506 | 19 | - | 26472758 | Jiyoye | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.3969556396774443 | [446] | [255] | -3 | hSpCas9 | negative selection | 186263 | 44217810 | 44217833 | 19 | + | 26472758 | Jiyoye | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | 0.4071753815058736 | [34] | [34] | 3 | hSpCas9 | negative selection | 186266 | 44228523 | 44228546 | 19 | + | 26472758 | KBM7 | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.5120520860205937 | [1749,1608] | [1347,928] | 5 | hSpCas9 | negative selection | 377375 | 44217817 | 44217840 | 19 | - | 26472758 | KBM7 | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.22837950779384952 | [1196,1064] | [474,753] | 2 | hSpCas9 | negative selection | 377376 | 44228498 | 44228521 | 19 | + | 26472758 | KBM7 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.5116043850133212 | [1227,727] | [629,651] | 5 | hSpCas9 | negative selection | 377377 | 44228469 | 44228492 | 19 | + | 26472758 | KBM7 | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -0.13300035345648498 | [917,685] | [359,322] | -1 | hSpCas9 | negative selection | 377378 | 44228550 | 44228573 | 19 | + | 26472758 | KBM7 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | 1.1642110335782592 | [433,215] | [192,456] | 9 | hSpCas9 | negative selection | 377379 | 44217796 | 44217819 | 19 | - | 26472758 | KBM7 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 0.0429572656896052 | [652,461] | [282,251] | 0 | hSpCas9 | negative selection | 377380 | 44228483 | 44228506 | 19 | - | 26472758 | KBM7 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.7003623575187998 | [1619,1274] | [1176,1026] | 7 | hSpCas9 | negative selection | 377381 | 44217810 | 44217833 | 19 | + | 26472758 | KBM7 | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | -0.6532712637591949 | [140,283] | [74,57] | -5 | hSpCas9 | negative selection | 377384 | 44228523 | 44228546 | 19 | + | 26472758 | Raji | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.5649456512990005 | [701] | [240] | 5 | hSpCas9 | negative selection | 568493 | 44217817 | 44217840 | 19 | - | 26472758 | Raji | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | -0.04195440567193054 | [660] | [148] | 0 | hSpCas9 | negative selection | 568494 | 44228498 | 44228521 | 19 | + | 26472758 | Raji | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.3162489657743258 | [397] | [114] | 3 | hSpCas9 | negative selection | 568495 | 44228469 | 44228492 | 19 | + | 26472758 | Raji | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -0.44343074293571116 | [333] | [56] | -4 | hSpCas9 | negative selection | 568496 | 44228550 | 44228573 | 19 | + | 26472758 | Raji | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | 0.4069438172325073 | [181] | [55] | 4 | hSpCas9 | negative selection | 568497 | 44217796 | 44217819 | 19 | - | 26472758 | Raji | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 1.5303262327377896 | [181] | [121] | 9 | hSpCas9 | negative selection | 568498 | 44228483 | 44228506 | 19 | - | 26472758 | Raji | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.06568117359928016 | [919] | [203] | 0 | hSpCas9 | negative selection | 568499 | 44217810 | 44217833 | 19 | + | 26472758 | Raji | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | -0.7819130002201807 | [162] | [21] | -5 | hSpCas9 | negative selection | 568502 | 44228523 | 44228546 | 19 | + | 26472758 | K562 | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | -0.21326310902089074 | [1441] | [1049] | -1 | hSpCas9 | negative selection | 759611 | 44217817 | 44217840 | 19 | - | 26472758 | K562 | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 1.0284362599316297 | [916] | [1578] | 8 | hSpCas9 | negative selection | 759612 | 44228498 | 44228521 | 19 | + | 26472758 | K562 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.20124473564316026 | [729] | [535] | -1 | hSpCas9 | negative selection | 759613 | 44228469 | 44228492 | 19 | + | 26472758 | K562 | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -2.4711278828648537 | [623] | [94] | -8 | hSpCas9 | negative selection | 759614 | 44228550 | 44228573 | 19 | + | 26472758 | K562 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | -0.3693027660361331 | [455] | [297] | -2 | hSpCas9 | negative selection | 759615 | 44217796 | 44217819 | 19 | - | 26472758 | K562 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 0.40325455044695324 | [652] | [728] | 3 | hSpCas9 | negative selection | 759616 | 44228483 | 44228506 | 19 | - | 26472758 | K562 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.506066593229278 | [1040] | [1247] | 4 | hSpCas9 | negative selection | 759617 | 44217810 | 44217833 | 19 | + | 26472758 | K562 | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | -0.13409289558728266 | [168] | [129] | -1 | hSpCas9 | negative selection | 759620 | 44217796 | 44217819 | 19 | - | 24336569 | HL60 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 0.19155439377751948 | [83] | [202] | 1 | hSpCas9 | negative selection | 2309606 | 44217842 | 44217865 | 19 | - | 24336569 | HL60 | viability | TCCTTTACGTACCTGAAACTTGG | ZNF227 | ENSG00000131115 | 0.019622024485418166 | [61] | [132] | 0 | hSpCas9 | negative selection | 2309607 | 44228465 | 44228488 | 19 | + | 24336569 | HL60 | viability | ATGTGGCTGTGGTCTTCTCCAGG | ZNF227 | ENSG00000131115 | 0.7489744345417493 | [123] | [440] | 6 | hSpCas9 | negative selection | 2309608 | 44228483 | 44228506 | 19 | - | 24336569 | HL60 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.36386383132962113 | [359] | [591] | -3 | hSpCas9 | negative selection | 2309609 | 44228498 | 44228521 | 19 | + | 24336569 | HL60 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.4474256082103139 | [577] | [896] | -4 | hSpCas9 | negative selection | 2309610 | 44228520 | 44228543 | 19 | + | 24336569 | HL60 | viability | GAAGCTGTACCGAGATGTCATGG | ZNF227 | ENSG00000131115 | -0.15331980891657127 | [1131] | [2153] | -1 | hSpCas9 | negative selection | 2309611 | 44228529 | 44228552 | 19 | - | 24336569 | HL60 | viability | AGTTCTCCACCATGACATCTCGG | ZNF227 | ENSG00000131115 | 1.6785033188989256 | [167] | [1137] | 9 | hSpCas9 | negative selection | 2309612 | 44228550 | 44228573 | 19 | + | 24336569 | HL60 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | -1.2690911038046677 | [409] | [359] | -8 | hSpCas9 | negative selection | 2309613 | 44228559 | 44228582 | 19 | - | 24336569 | HL60 | viability | TGTCCTCACCCACTGCAACCAGG | ZNF227 | ENSG00000131115 | -0.11413028954921867 | [267] | [523] | -1 | hSpCas9 | negative selection | 2309614 | 44217796 | 44217819 | 19 | - | 24336569 | KBM7 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 0.18800937724224198 | [83] | [260] | 1 | hSpCas9 | negative selection | 2376783 | 44217842 | 44217865 | 19 | - | 24336569 | KBM7 | viability | TCCTTTACGTACCTGAAACTTGG | ZNF227 | ENSG00000131115 | -0.5238147823759677 | [203] | [386] | -4 | hSpCas9 | negative selection | 2376784 | 44228465 | 44228488 | 19 | + | 24336569 | KBM7 | viability | ATGTGGCTGTGGTCTTCTCCAGG | ZNF227 | ENSG00000131115 | -0.7549028785274732 | [171] | [277] | -5 | hSpCas9 | negative selection | 2376785 | 44228483 | 44228506 | 19 | - | 24336569 | KBM7 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -1.8331570953540623 | [306] | [234] | -8 | hSpCas9 | negative selection | 2376786 | 44228498 | 44228521 | 19 | + | 24336569 | KBM7 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.3766495440731178 | [424] | [1504] | 3 | hSpCas9 | negative selection | 2376787 | 44228520 | 44228543 | 19 | + | 24336569 | KBM7 | viability | GAAGCTGTACCGAGATGTCATGG | ZNF227 | ENSG00000131115 | 0.21794508326289308 | [829] | [2632] | 2 | hSpCas9 | negative selection | 2376788 | 44228529 | 44228552 | 19 | - | 24336569 | KBM7 | viability | AGTTCTCCACCATGACATCTCGG | ZNF227 | ENSG00000131115 | -0.014087331233556821 | [300] | [812] | 0 | hSpCas9 | negative selection | 2376789 | 44228550 | 44228573 | 19 | + | 24336569 | KBM7 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | 0.27375574590355967 | [231] | [764] | 2 | hSpCas9 | negative selection | 2376790 | 44228559 | 44228582 | 19 | - | 24336569 | KBM7 | viability | TGTCCTCACCCACTGCAACCAGG | ZNF227 | ENSG00000131115 | 0.40699036392955384 | [218] | [791] | 4 | hSpCas9 | negative selection | 2376791 | 44212345 | 44212368 | 19 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | ACGGAGCGAGCGAGTGAGAGAGG | ZNF227 | ENSG00000131115 | 0.12490412111711885 | [6,134] | [4,29] | 0 | dCas9-VP64 | positive selection | 2426471 | 44212398 | 44212421 | 19 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CGAAGAGGGCGGCACCTGGATGG | ZNF227 | ENSG00000131115 | 0.7551421186770961 | [299,40] | [108,11] | 3 | dCas9-VP64 | positive selection | 2426472 | 44212426 | 44212449 | 19 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CGTTTCCCAGAACTTCCAGAAGG | ZNF227 | ENSG00000131115 | 0.10680602808619821 | [246,286] | [42,84] | 0 | dCas9-VP64 | positive selection | 2426473 | 44212345 | 44212368 | 19 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | ACGGAGCGAGCGAGTGAGAGAGG | ZNF227 | ENSG00000131115 | -1.2008306077950275 | [184,67] | [25,9] | -9 | dCas9-VP64 | positive selection | 2521726 | 44212398 | 44212421 | 19 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CGAAGAGGGCGGCACCTGGATGG | ZNF227 | ENSG00000131115 | 0.2125647560603816 | [160,36] | [31,42] | 1 | dCas9-VP64 | positive selection | 2521727 | 44212426 | 44212449 | 19 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CGTTTCCCAGAACTTCCAGAAGG | ZNF227 | ENSG00000131115 | -0.9835163140569321 | [306,227] | [45,41] | -8 | dCas9-VP64 | positive selection | 2521728 | 44228499 | 44228522 | 19 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.06455769487383071 | [4,3] | [3,2] | -1 | hSpCas9 | positive selection | 3034106 | 44228499 | 44228522 | 19 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -1.0631308888355002 | [4,4] | [1,0] | -9 | hSpCas9 | positive selection | 3101964 | 44228498 | 44228521 | | + | 24336571 | A375 | resistance to PLX after 7 days | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.07806181409690485 | [10,9] | [11,9] | 2 | hSpCas9 | positive selection | 3157175 | 44228483 | 44228506 | | - | 24336571 | A375 | resistance to PLX after 7 days | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.36246735875625924 | [30,22] | [18,21] | -8 | hSpCas9 | positive selection | 3157176 | 44228498 | 44228521 | | + | 24336571 | A375 | resistance to PLX after 14 days | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 1.138868769876042 | [7,5] | [6,6] | 8 | hSpCas9 | positive selection | 3214968 | 44228483 | 44228506 | | - | 24336571 | A375 | resistance to PLX after 14 days | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.09712988569616776 | [29,21] | [11,10] | -1 | hSpCas9 | positive selection | 3214969 | 44228498 | 44228521 | | + | 24336571 | A375 | viability after 7 days | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.3337498967373816 | [8] | [10,9] | 5 | hSpCas9 | negative selection | 3272761 | 44228483 | 44228506 | | - | 24336571 | A375 | viability after 7 days | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.22494940058617985 | [23] | [30,22] | 3 | hSpCas9 | negative selection | 3272762 | 44228498 | 44228521 | | + | 24336571 | A375 | viability after 14 days | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.171300922230455 | [8] | [7,5] | -2 | hSpCas9 | negative selection | 3330554 | 44228483 | 44228506 | | - | 24336571 | A375 | viability after 14 days | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.20660941541418043 | [23] | [29,21] | 2 | hSpCas9 | negative selection | 3330555 | 44228483 | 44228506 | 19 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.43616074605349014 | [206,206] | [0,0] | -3 | hSpCas9 | positive selection | 3402645 | 44228498 | 44228521 | 19 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.913592368574786 | [] | [] | 3 | hSpCas9 | negative selection | 3473426 | 44228498 | 44228521 | 19 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 3.08898051354627 | [] | [] | 5 | hSpCas9 | negative selection | 3581176 | 44228498 | 44228521 | 19 | + | 26780180 | A375 | viability (Avana lentiGuide) | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.487237408249204 | [] | [] | 0 | hSpCas9 | negative selection | 3689835 | 44228498 | 44228521 | 19 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.17077376148124937 | [4] | [6,4] | 4 | hSpCas9 | positive selection | 3798442 | 44228498 | 44228521 | 19 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.16602993614835077 | [5] | [5,5] | 4 | hSpCas9 | positive selection | 3907049 | 44228498 | 44228521 | 19 | + | 26780180 | A375 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.333904988606518 | [] | [] | 0 | hSpCas9 | negative selection | 4015143 | 44228483 | 44228506 | 19 | - | 26780180 | A375 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 1.39891925564206 | [] | [] | 7 | hSpCas9 | negative selection | 4015144 | 44228498 | 44228521 | 19 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.352378433539329 | [] | [] | 1 | hSpCas9 | negative selection | 4123109 | 44228483 | 44228506 | 19 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 1.68834789223312 | [] | [] | 8 | hSpCas9 | negative selection | 4123110 | 44228498 | 44228521 | 19 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.21941302559139797 | [3] | [2,2] | 5 | hSpCas9 | positive selection | 4184193 | 44228483 | 44228506 | 19 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.15062762877618896 | [4] | [2,3] | 4 | hSpCas9 | positive selection | 4184194 | 44228498 | 44228521 | 19 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.11473704452859429 | [3] | [3,1,1,0] | -2 | hSpCas9 | positive selection | 4248215 | 44228483 | 44228506 | 19 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.1332198339279977 | [3] | [0,3,4,0] | 1 | hSpCas9 | positive selection | 4248216 | 44228498 | 44228521 | 19 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.4619233404433891 | [3] | [3,3] | 8 | hSpCas9 | positive selection | 4309243 | 44228483 | 44228506 | 19 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.16975949054581776 | [3] | [2,1] | -3 | hSpCas9 | positive selection | 4373492 | 44212903 | 44212926 | 19 | + | 27661255 | K562 | viability | GGTGGCACCTGATACTGGGTTGG | ZNF227 | ENSG00000131115 | -0.03228367699470025 | [1267,1222] | [1094,869] | -1 | dCas9-KRAB | negative selection | 5524443 | 44212631 | 44212654 | 19 | - | 27661255 | K562 | viability | GAGCGCCTATTCCCAAGCACAGG | ZNF227 | ENSG00000131115 | 0.22401169634470877 | [472,696] | [561,524] | 7 | dCas9-KRAB | negative selection | 5524444 | 44212788 | 44212811 | 19 | - | 27661255 | K562 | viability | GAAACAGGAGCGCGGATCATAGG | ZNF227 | ENSG00000131115 | 0.23284058320537682 | [1065,1486] | [1256,1134] | 7 | dCas9-KRAB | negative selection | 5524445 | 44228498 | 44228521 | 19 | + | 27260156 | BXPC3 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.10689479703042531 | [623] | [624,707,696,794] | 2 | hSpCas9 | negative selection | 5581703 | 44228483 | 44228506 | 19 | - | 27260156 | BXPC3 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.3183856125214025 | [675] | [508,543,615,607] | -6 | hSpCas9 | negative selection | 5645952 | 44228498 | 44228521 | 19 | + | 27260156 | A673 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.22928418818052992 | [623] | [908,892,820,892] | 5 | hSpCas9 | negative selection | 5702954 | 44228483 | 44228506 | 19 | - | 27260156 | A673 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.2618429656461656 | [675] | [688,693,672,649] | -6 | hSpCas9 | negative selection | 5767203 | 44228498 | 44228521 | 19 | + | 27260156 | A375 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.3376483847657466 | [623] | [832,1195,896,805] | 5 | hSpCas9 | negative selection | 5824205 | 44228483 | 44228506 | 19 | - | 27260156 | A375 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.10671045316605621 | [675] | [919,574,1100,772] | 1 | hSpCas9 | negative selection | 5888454 | 44228498 | 44228521 | 19 | + | 27260156 | COLO741 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.10341000091152525 | [623] | [725,961,867] | 2 | hSpCas9 | negative selection | 5945456 | 44228483 | 44228506 | 19 | - | 27260156 | COLO741 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.2909719372954688 | [675] | [704,673,734] | -6 | hSpCas9 | negative selection | 6009705 | 44228498 | 44228521 | 19 | + | 27260156 | CAL120 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.9127042145401636 | [623] | [1491,1358,1536] | 9 | hSpCas9 | negative selection | 6066707 | 44228483 | 44228506 | 19 | - | 27260156 | CAL120 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.07661274946521895 | [675] | [1198,615,640] | -1 | hSpCas9 | negative selection | 6130956 | 44228498 | 44228521 | 19 | + | 27260156 | CADOES1 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.10032077007274315 | [623] | [569,831,571,510] | 1 | hSpCas9 | negative selection | 6187958 | 44228483 | 44228506 | 19 | - | 27260156 | CADOES1 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.011337313026423046 | [675] | [643,523,649,678] | 0 | hSpCas9 | negative selection | 6252207 | 44228498 | 44228521 | 19 | + | 27260156 | EWS502 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.36176061753750915 | [623] | [769,589,1065,1001] | 6 | hSpCas9 | negative selection | 6309209 | 44228483 | 44228506 | 19 | - | 27260156 | EWS502 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.04836738821483222 | [675] | [857,547,607,740] | -1 | hSpCas9 | negative selection | 6373458 | 44228498 | 44228521 | 19 | + | 27260156 | EW8 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.1028199177765407 | [623] | [611,530,466,580] | 1 | hSpCas9 | negative selection | 6430460 | 44228483 | 44228506 | 19 | - | 27260156 | EW8 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.09083845083906289 | [675] | [666,393,522,486] | -2 | hSpCas9 | negative selection | 6494709 | 44228498 | 44228521 | 19 | + | 27260156 | CORL105 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.2528132816400896 | [623] | [1050,802,886,750] | 5 | hSpCas9 | negative selection | 6551711 | 44228483 | 44228506 | 19 | - | 27260156 | CORL105 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.030076415944997492 | [675] | [720,759,911,726] | 0 | hSpCas9 | negative selection | 6615960 | 44228498 | 44228521 | 19 | + | 27260156 | HS294T | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.1953821682238483 | [623] | [266,231,318,290] | 2 | hSpCas9 | negative selection | 6672962 | 44228483 | 44228506 | 19 | - | 27260156 | HS294T | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.3573832865937432 | [675] | [142,141,191,374] | -5 | hSpCas9 | negative selection | 6737211 | 44228498 | 44228521 | 19 | + | 27260156 | HCC44 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.3937754354891653 | [623] | [950,739,1357,760] | 6 | hSpCas9 | negative selection | 6794213 | 44228483 | 44228506 | 19 | - | 27260156 | HCC44 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.05398916989027147 | [675] | [863,497,1228,703] | 0 | hSpCas9 | negative selection | 6858462 | 44228498 | 44228521 | 19 | + | 27260156 | G402 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.05283166428515107 | [623] | [859,702,638,746] | 0 | hSpCas9 | negative selection | 6915464 | 44228483 | 44228506 | 19 | - | 27260156 | G402 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.13587791888820244 | [675] | [1038,716,587,1267] | 1 | hSpCas9 | negative selection | 6979713 | 44228498 | 44228521 | 19 | + | 27260156 | L33 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.6013209817699847 | [623] | [999,379,558,967] | 9 | hSpCas9 | negative selection | 7036715 | 44228483 | 44228506 | 19 | - | 27260156 | L33 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.35633169129009085 | [675] | [440,239,303,602] | -7 | hSpCas9 | negative selection | 7100964 | 44228498 | 44228521 | 19 | + | 27260156 | K562 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.30004203786362105 | [623] | [336,563,471,423] | -4 | hSpCas9 | negative selection | 7157966 | 44228483 | 44228506 | 19 | - | 27260156 | K562 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.6144169481792211 | [675] | [260,304,559,420] | -6 | hSpCas9 | negative selection | 7222215 | 44228498 | 44228521 | 19 | + | 27260156 | HT29 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.16171172943770157 | [623] | [917,969,831,701] | 3 | hSpCas9 | negative selection | 7279217 | 44228483 | 44228506 | 19 | - | 27260156 | HT29 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.4279240169414812 | [675] | [505,717,622,594] | -7 | hSpCas9 | negative selection | 7343466 | 44228498 | 44228521 | 19 | + | 27260156 | MHHES1 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.5253106789325253 | [623] | [780,1206,1321,764] | 8 | hSpCas9 | negative selection | 7400468 | 44228483 | 44228506 | 19 | - | 27260156 | MHHES1 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.1373369867820476 | [675] | [826,831,680,490] | -3 | hSpCas9 | negative selection | 7464717 | 44228498 | 44228521 | 19 | + | 27260156 | MEWO | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.19935621763383088 | [623] | [783,624,623] | 4 | hSpCas9 | negative selection | 7521719 | 44228483 | 44228506 | 19 | - | 27260156 | MEWO | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.6054975989384581 | [675] | [445,371,434] | -8 | hSpCas9 | negative selection | 7585968 | 44228498 | 44228521 | 19 | + | 27260156 | LNCAPCLONEFGC | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.36647925636510764 | [623] | [803,706,833,584] | 6 | hSpCas9 | negative selection | 7642970 | 44228483 | 44228506 | 19 | - | 27260156 | LNCAPCLONEFGC | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.0876664036400252 | [675] | [779,624,632,560] | 1 | hSpCas9 | negative selection | 7707219 | 44228498 | 44228521 | 19 | + | 27260156 | PANC0327 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.11194473460035281 | [623] | [563,742,421,296] | -2 | hSpCas9 | negative selection | 7764221 | 44228483 | 44228506 | 19 | - | 27260156 | PANC0327 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.07514785359391352 | [675] | [888,489,332,856] | 1 | hSpCas9 | negative selection | 7828470 | 44228498 | 44228521 | 19 | + | 27260156 | NCIH2009 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.001204187502388876 | [623] | [984,723,927] | 0 | hSpCas9 | negative selection | 7885472 | 44228483 | 44228506 | 19 | - | 27260156 | NCIH2009 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.09101881261678085 | [675] | [1109,931,659] | -1 | hSpCas9 | negative selection | 7949721 | 44228498 | 44228521 | 19 | + | 27260156 | NCIH1373 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.02693226937909321 | [623] | [934,359,934,150] | 0 | hSpCas9 | negative selection | 8006723 | 44228483 | 44228506 | 19 | - | 27260156 | NCIH1373 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.04256747258195426 | [675] | [871,509,885,235] | 0 | hSpCas9 | negative selection | 8070972 | 44228498 | 44228521 | 19 | + | 27260156 | PATU8902 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.019576598771638365 | [623] | [890,915,714,947] | 0 | hSpCas9 | negative selection | 8127974 | 44228483 | 44228506 | 19 | - | 27260156 | PATU8902 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.35346426434535194 | [675] | [1198,932,1143,1585] | 3 | hSpCas9 | negative selection | 8192223 | 44228498 | 44228521 | 19 | + | 27260156 | PANC1 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.6305638617029801 | [623] | [824,1185,806,598] | 8 | hSpCas9 | negative selection | 8249225 | 44228483 | 44228506 | 19 | - | 27260156 | PANC1 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.09111929600635882 | [675] | [572,818,573,301] | -1 | hSpCas9 | negative selection | 8313474 | 44228498 | 44228521 | 19 | + | 27260156 | PANC0813 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.28170012832992514 | [623] | [931,920,803,907] | 4 | hSpCas9 | negative selection | 8370476 | 44228483 | 44228506 | 19 | - | 27260156 | PANC0813 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.23231832253461154 | [675] | [817,649,599,648] | -4 | hSpCas9 | negative selection | 8434725 | 44228498 | 44228521 | 19 | + | 27260156 | RDES | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.25718175164757157 | [623] | [657,781,919,1141] | 4 | hSpCas9 | negative selection | 8491727 | 44228483 | 44228506 | 19 | - | 27260156 | RDES | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.05748431111341307 | [675] | [569,715,773,984] | -1 | hSpCas9 | negative selection | 8555976 | 44228498 | 44228521 | 19 | + | 27260156 | PC3 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.023261602120797364 | [623] | [284,704,1019,776] | 0 | hSpCas9 | negative selection | 8612978 | 44228483 | 44228506 | 19 | - | 27260156 | PC3 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.48773004276422166 | [675] | [292,595,763,404] | -8 | hSpCas9 | negative selection | 8677227 | 44228498 | 44228521 | 19 | + | 27260156 | PATU8988T | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.12091099361370444 | [623] | [497,764,615,762] | 2 | hSpCas9 | negative selection | 8734229 | 44228483 | 44228506 | 19 | - | 27260156 | PATU8988T | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.2973308675012173 | [675] | [732,694,237,474] | -5 | hSpCas9 | negative selection | 8798478 | 44228498 | 44228521 | 19 | + | 27260156 | T47D | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.2570928101246422 | [623] | [904,838,834,899] | 5 | hSpCas9 | negative selection | 8855480 | 44228483 | 44228506 | 19 | - | 27260156 | T47D | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.304835321579435 | [675] | [628,558,653,716] | -6 | hSpCas9 | negative selection | 8919729 | 44228498 | 44228521 | 19 | + | 27260156 | SU8686 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.35305352349487334 | [623] | [849,616,680,1063] | 6 | hSpCas9 | negative selection | 8976731 | 44228483 | 44228506 | 19 | - | 27260156 | SU8686 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.1254289557278444 | [675] | [490,637,549,815] | -2 | hSpCas9 | negative selection | 9040980 | 44228498 | 44228521 | 19 | + | 27260156 | SKES1 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.25167966038179174 | [623] | [908,956,607,555] | 5 | hSpCas9 | negative selection | 9097982 | 44228483 | 44228506 | 19 | - | 27260156 | SKES1 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.11583317035214852 | [675] | [619,748,579,556] | -3 | hSpCas9 | negative selection | 9162231 | 44228498 | 44228521 | 19 | + | 27260156 | TOV112D | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.06413898600492712 | [623] | [595,718,446,855] | 1 | hSpCas9 | negative selection | 9219233 | 44228483 | 44228506 | 19 | - | 27260156 | TOV112D | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.009508918011369771 | [675] | [552,646,875,598] | 0 | hSpCas9 | negative selection | 9283482 | 44228498 | 44228521 | 19 | + | 27260156 | TC71 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.2724605627374777 | [623] | [905,857,614,859] | 6 | hSpCas9 | negative selection | 9340484 | 44228483 | 44228506 | 19 | - | 27260156 | TC71 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.21571741658729549 | [675] | [702,587,635,562] | -5 | hSpCas9 | negative selection | 9404733 | 44228498 | 44228521 | 19 | + | 27260156 | TC32 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.07783686394600159 | [623] | [512,340,647,805] | -1 | hSpCas9 | negative selection | 9461735 | 44228483 | 44228506 | 19 | - | 27260156 | TC32 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.08633486540978558 | [675] | [555,508,747,608] | -1 | hSpCas9 | negative selection | 9525984 | 44228523 | 44228546 | 19 | + | 28162770 | P31FUJ | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.19937937981471765 | [480] | [648] | 2 | hSpCas9 | negative selection | 10269476 | 44217817 | 44217840 | 19 | - | 28162770 | P31FUJ | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.3153603781038259 | [674] | [986] | 3 | hSpCas9 | negative selection | 10269477 | 44228498 | 44228521 | 19 | + | 28162770 | P31FUJ | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.16257501811343977 | [313] | [412] | 1 | hSpCas9 | negative selection | 10269478 | 44228469 | 44228492 | 19 | + | 28162770 | P31FUJ | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -0.6208194897595135 | [334] | [255] | -5 | hSpCas9 | negative selection | 10269479 | 44228550 | 44228573 | 19 | + | 28162770 | P31FUJ | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | -0.6910075628495959 | [146] | [106] | -5 | hSpCas9 | negative selection | 10269480 | 44217796 | 44217819 | 19 | - | 28162770 | P31FUJ | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 0.8764650071543093 | [196] | [424] | 8 | hSpCas9 | negative selection | 10269481 | 44228483 | 44228506 | 19 | - | 28162770 | P31FUJ | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.35507189172668063 | [824] | [1239] | 4 | hSpCas9 | negative selection | 10269482 | 44217810 | 44217833 | 19 | + | 28162770 | P31FUJ | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | 0.05955277508963652 | [137] | [168] | 0 | hSpCas9 | negative selection | 10269483 | 44228523 | 44228546 | 19 | + | 28162770 | TF1 | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | NaN | [NaN] | [310] | 1 | hSpCas9 | negative selection | 10438842 | 44217817 | 44217840 | 19 | - | 28162770 | TF1 | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | NaN | [NaN] | [722] | 1 | hSpCas9 | negative selection | 10438843 | 44228498 | 44228521 | 19 | + | 28162770 | TF1 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | NaN | [NaN] | [334] | 1 | hSpCas9 | negative selection | 10438844 | 44228469 | 44228492 | 19 | + | 28162770 | TF1 | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | NaN | [NaN] | [48] | 1 | hSpCas9 | negative selection | 10438845 | 44228550 | 44228573 | 19 | + | 28162770 | TF1 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | NaN | [NaN] | [86] | 1 | hSpCas9 | negative selection | 10438846 | 44217796 | 44217819 | 19 | - | 28162770 | TF1 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | NaN | [NaN] | [153] | 1 | hSpCas9 | negative selection | 10438847 | 44228483 | 44228506 | 19 | - | 28162770 | TF1 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | NaN | [NaN] | [856] | 1 | hSpCas9 | negative selection | 10438848 | 44217810 | 44217833 | 19 | + | 28162770 | TF1 | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | NaN | [NaN] | [63] | 1 | hSpCas9 | negative selection | 10438849 | 44228523 | 44228546 | 19 | + | 28162770 | SKM1 | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.15996437914773276 | [160] | [317] | 1 | hSpCas9 | negative selection | 10608208 | 44217817 | 44217840 | 19 | - | 28162770 | SKM1 | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.2654611432283338 | [151] | [322] | 2 | hSpCas9 | negative selection | 10608209 | 44228498 | 44228521 | 19 | + | 28162770 | SKM1 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.1664472294707955 | [112] | [177] | -1 | hSpCas9 | negative selection | 10608210 | 44228469 | 44228492 | 19 | + | 28162770 | SKM1 | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -0.3167663897715836 | [92] | [131] | -3 | hSpCas9 | negative selection | 10608211 | 44228550 | 44228573 | 19 | + | 28162770 | SKM1 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | 0.17799830197799452 | [41] | [83] | 1 | hSpCas9 | negative selection | 10608212 | 44217796 | 44217819 | 19 | - | 28162770 | SKM1 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 0.17799830197799443 | [62] | [125] | 1 | hSpCas9 | negative selection | 10608213 | 44228483 | 44228506 | 19 | - | 28162770 | SKM1 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.4422108990090696 | [203] | [489] | 4 | hSpCas9 | negative selection | 10608214 | 44217810 | 44217833 | 19 | + | 28162770 | SKM1 | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | -0.40696419874316137 | [23] | [31] | -3 | hSpCas9 | negative selection | 10608215 | 44228523 | 44228546 | 19 | + | 28162770 | SKM1 | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.15996437914773276 | [160] | [317] | 1 | hSpCas9 | negative selection | 10777574 | 44217817 | 44217840 | 19 | - | 28162770 | SKM1 | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.2654611432283338 | [151] | [322] | 2 | hSpCas9 | negative selection | 10777575 | 44228498 | 44228521 | 19 | + | 28162770 | SKM1 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.1664472294707955 | [112] | [177] | -1 | hSpCas9 | negative selection | 10777576 | 44228469 | 44228492 | 19 | + | 28162770 | SKM1 | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -0.3167663897715836 | [92] | [131] | -3 | hSpCas9 | negative selection | 10777577 | 44228550 | 44228573 | 19 | + | 28162770 | SKM1 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | 0.17799830197799452 | [41] | [83] | 1 | hSpCas9 | negative selection | 10777578 | 44217796 | 44217819 | 19 | - | 28162770 | SKM1 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 0.17799830197799443 | [62] | [125] | 1 | hSpCas9 | negative selection | 10777579 | 44228483 | 44228506 | 19 | - | 28162770 | SKM1 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.4422108990090696 | [203] | [489] | 4 | hSpCas9 | negative selection | 10777580 | 44217810 | 44217833 | 19 | + | 28162770 | SKM1 | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | -0.40696419874316137 | [23] | [31] | -3 | hSpCas9 | negative selection | 10777581 | 44228523 | 44228546 | 19 | + | 28162770 | PL21 | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.3880311624610815 | [531] | [302] | 3 | hSpCas9 | negative selection | 10946940 | 44217817 | 44217840 | 19 | - | 28162770 | PL21 | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.4595717836429185 | [400] | [239] | 4 | hSpCas9 | negative selection | 10946941 | 44228498 | 44228521 | 19 | + | 28162770 | PL21 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.41479638704616284 | [373] | [216] | 3 | hSpCas9 | negative selection | 10946942 | 44228469 | 44228492 | 19 | + | 28162770 | PL21 | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -0.38482288623183597 | [332] | [110] | -3 | hSpCas9 | negative selection | 10946943 | 44228550 | 44228573 | 19 | + | 28162770 | PL21 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | 0.14951354141935225 | [202] | [97] | 1 | hSpCas9 | negative selection | 10946944 | 44217796 | 44217819 | 19 | - | 28162770 | PL21 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 1.0125126113135487 | [204] | [179] | 8 | hSpCas9 | negative selection | 10946945 | 44228483 | 44228506 | 19 | - | 28162770 | PL21 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.5655463460435637 | [620] | [399] | 5 | hSpCas9 | negative selection | 10946946 | 44217810 | 44217833 | 19 | + | 28162770 | PL21 | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | 1.1006039409384056 | [59] | [55] | 8 | hSpCas9 | negative selection | 10946947 | 44228523 | 44228546 | 19 | + | 28162770 | P31FUJ | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.19937937981471765 | [480] | [648] | 2 | hSpCas9 | negative selection | 11116306 | 44217817 | 44217840 | 19 | - | 28162770 | P31FUJ | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.3153603781038259 | [674] | [986] | 3 | hSpCas9 | negative selection | 11116307 | 44228498 | 44228521 | 19 | + | 28162770 | P31FUJ | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.16257501811343977 | [313] | [412] | 1 | hSpCas9 | negative selection | 11116308 | 44228469 | 44228492 | 19 | + | 28162770 | P31FUJ | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -0.6208194897595135 | [334] | [255] | -5 | hSpCas9 | negative selection | 11116309 | 44228550 | 44228573 | 19 | + | 28162770 | P31FUJ | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | -0.6910075628495959 | [146] | [106] | -5 | hSpCas9 | negative selection | 11116310 | 44217796 | 44217819 | 19 | - | 28162770 | P31FUJ | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 0.8764650071543093 | [196] | [424] | 8 | hSpCas9 | negative selection | 11116311 | 44228483 | 44228506 | 19 | - | 28162770 | P31FUJ | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.35507189172668063 | [824] | [1239] | 4 | hSpCas9 | negative selection | 11116312 | 44217810 | 44217833 | 19 | + | 28162770 | P31FUJ | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | 0.05955277508963652 | [137] | [168] | 0 | hSpCas9 | negative selection | 11116313 | 44228523 | 44228546 | 19 | + | 28162770 | OCIAML5 | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.39958107466799064 | [264] | [630] | 3 | hSpCas9 | negative selection | 11285672 | 44217817 | 44217840 | 19 | - | 28162770 | OCIAML5 | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.9861460790714687 | [336] | [1204] | 8 | hSpCas9 | negative selection | 11285673 | 44228498 | 44228521 | 19 | + | 28162770 | OCIAML5 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.34735916365042396 | [198] | [456] | 3 | hSpCas9 | negative selection | 11285674 | 44228469 | 44228492 | 19 | + | 28162770 | OCIAML5 | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -0.8240521946944005 | [152] | [155] | -5 | hSpCas9 | negative selection | 11285675 | 44228550 | 44228573 | 19 | + | 28162770 | OCIAML5 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | 0.7328959298571591 | [105] | [317] | 6 | hSpCas9 | negative selection | 11285676 | 44217796 | 44217819 | 19 | - | 28162770 | OCIAML5 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | -0.16474235251316308 | [135] | [218] | -1 | hSpCas9 | negative selection | 11285677 | 44228483 | 44228506 | 19 | - | 28162770 | OCIAML5 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.4484571848828327 | [420] | [1036] | 4 | hSpCas9 | negative selection | 11285678 | 44217810 | 44217833 | 19 | + | 28162770 | OCIAML5 | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | 1.3827095749282834 | [57] | [272] | 9 | hSpCas9 | negative selection | 11285679 | 44228523 | 44228546 | 19 | + | 28162770 | EOL1 | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.8107940572630292 | [975] | [901] | 7 | hSpCas9 | negative selection | 11455038 | 44217817 | 44217840 | 19 | - | 28162770 | EOL1 | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.17422379454930947 | [650] | [386] | 1 | hSpCas9 | negative selection | 11455039 | 44228498 | 44228521 | 19 | + | 28162770 | EOL1 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.36351993108531055 | [806] | [546] | 3 | hSpCas9 | negative selection | 11455040 | 44228469 | 44228492 | 19 | + | 28162770 | EOL1 | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -0.7147692585890226 | [594] | [190] | -5 | hSpCas9 | negative selection | 11455041 | 44228550 | 44228573 | 19 | + | 28162770 | EOL1 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | -1.5049602105166424 | [333] | [61] | -7 | hSpCas9 | negative selection | 11455042 | 44217796 | 44217819 | 19 | - | 28162770 | EOL1 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 0.40224930563154926 | [427] | [297] | 3 | hSpCas9 | negative selection | 11455043 | 44228483 | 44228506 | 19 | - | 28162770 | EOL1 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.24485212397823286 | [888] | [554] | 2 | hSpCas9 | negative selection | 11455044 | 44217810 | 44217833 | 19 | + | 28162770 | EOL1 | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | -0.09071898508277587 | [94] | [46] | 0 | hSpCas9 | negative selection | 11455045 | 44228523 | 44228546 | 19 | + | 28162770 | MOLM13 | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.6885017964357409 | [810] | [944] | 5 | hSpCas9 | negative selection | 11624404 | 44217817 | 44217840 | 19 | - | 28162770 | MOLM13 | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.747997300737314 | [783] | [951] | 5 | hSpCas9 | negative selection | 11624405 | 44228498 | 44228521 | 19 | + | 28162770 | MOLM13 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.11888175260093226 | [604] | [474] | 0 | hSpCas9 | negative selection | 11624406 | 44228469 | 44228492 | 19 | + | 28162770 | MOLM13 | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -0.7894426649250317 | [403] | [168] | -4 | hSpCas9 | negative selection | 11624407 | 44228550 | 44228573 | 19 | + | 28162770 | MOLM13 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | 1.1819318314306646 | [202] | [332] | 8 | hSpCas9 | negative selection | 11624408 | 44217796 | 44217819 | 19 | - | 28162770 | MOLM13 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 0.19724179160090974 | [303] | [251] | 1 | hSpCas9 | negative selection | 11624409 | 44228483 | 44228506 | 19 | - | 28162770 | MOLM13 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.35197009424501124 | [815] | [752] | 2 | hSpCas9 | negative selection | 11624410 | 44217810 | 44217833 | 19 | + | 28162770 | MOLM13 | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | 1.7479973007373142 | [83] | [203] | 9 | hSpCas9 | negative selection | 11624411 | 44228523 | 44228546 | 19 | + | 28162770 | HEL | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.9143824144177499 | [723] | [873] | 7 | hSpCas9 | negative selection | 11793770 | 44217817 | 44217840 | 19 | - | 28162770 | HEL | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.5308459519294597 | [669] | [619] | 4 | hSpCas9 | negative selection | 11793771 | 44228498 | 44228521 | 19 | + | 28162770 | HEL | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.6172037398932193 | [455] | [447] | 5 | hSpCas9 | negative selection | 11793772 | 44228469 | 44228492 | 19 | + | 28162770 | HEL | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -2.0966699380941782 | [393] | [58] | -8 | hSpCas9 | negative selection | 11793773 | 44228550 | 44228573 | 19 | + | 28162770 | HEL | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | 0.18794362348377835 | [232] | [169] | 1 | hSpCas9 | negative selection | 11793774 | 44217796 | 44217819 | 19 | - | 28162770 | HEL | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 0.5977149073143616 | [357] | [346] | 5 | hSpCas9 | negative selection | 11793775 | 44228483 | 44228506 | 19 | - | 28162770 | HEL | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.08852064382063296 | [756] | [455] | 0 | hSpCas9 | negative selection | 11793776 | 44217810 | 44217833 | 19 | + | 28162770 | HEL | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | 0.20122912136032212 | [109] | [80] | 1 | hSpCas9 | negative selection | 11793777 | 44228523 | 44228546 | 19 | + | 28162770 | MV411 | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | -0.5517803218364903 | [662] | [380] | -4 | hSpCas9 | negative selection | 11963136 | 44217817 | 44217840 | 19 | - | 28162770 | MV411 | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.7283047863255643 | [497] | [694] | 6 | hSpCas9 | negative selection | 11963137 | 44228498 | 44228521 | 19 | + | 28162770 | MV411 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.09102312522325862 | [372] | [294] | 0 | hSpCas9 | negative selection | 11963138 | 44228469 | 44228492 | 19 | + | 28162770 | MV411 | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -1.4823682518105645 | [334] | [100] | -7 | hSpCas9 | negative selection | 11963139 | 44228550 | 44228573 | 19 | + | 28162770 | MV411 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | 0.3560788107865993 | [178] | [192] | 3 | hSpCas9 | negative selection | 11963140 | 44217796 | 44217819 | 19 | - | 28162770 | MV411 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 0.9204308158576524 | [248] | [396] | 8 | hSpCas9 | negative selection | 11963141 | 44228483 | 44228506 | 19 | - | 28162770 | MV411 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.23671114418971673 | [539] | [535] | 2 | hSpCas9 | negative selection | 11963142 | 44217810 | 44217833 | 19 | + | 28162770 | MV411 | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | -0.4491703057672898 | [46] | [28] | -3 | hSpCas9 | negative selection | 11963143 | 44228523 | 44228546 | 19 | + | 28162770 | MONOMAC1 | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | -0.03510463637077188 | [361] | [404] | 0 | hSpCas9 | negative selection | 12132502 | 44217817 | 44217840 | 19 | - | 28162770 | MONOMAC1 | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.9171929037535713 | [266] | [577] | 8 | hSpCas9 | negative selection | 12132503 | 44228498 | 44228521 | 19 | + | 28162770 | MONOMAC1 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | -0.3748239662748365 | [275] | [243] | -3 | hSpCas9 | negative selection | 12132504 | 44228469 | 44228492 | 19 | + | 28162770 | MONOMAC1 | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | 0.02447828933597318 | [234] | [273] | 0 | hSpCas9 | negative selection | 12132505 | 44228550 | 44228573 | 19 | + | 28162770 | MONOMAC1 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | 0.6654596291905114 | [120] | [219] | 6 | hSpCas9 | negative selection | 12132506 | 44217796 | 44217819 | 19 | - | 28162770 | MONOMAC1 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 1.6263078058789133 | [140] | [498] | 9 | hSpCas9 | negative selection | 12132507 | 44228483 | 44228506 | 19 | - | 28162770 | MONOMAC1 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | -0.2542105554467875 | [488] | [469] | -2 | hSpCas9 | negative selection | 12132508 | 44217810 | 44217833 | 19 | + | 28162770 | MONOMAC1 | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | 0.7047827590015425 | [37] | [70] | 6 | hSpCas9 | negative selection | 12132509 | 44228523 | 44228546 | 19 | + | 28162770 | OCIAML2 | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.08651473133923249 | [95] | [564] | 0 | hSpCas9 | negative selection | 12301868 | 44217817 | 44217840 | 19 | - | 28162770 | OCIAML2 | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.748412942764842 | [76] | [716] | 7 | hSpCas9 | negative selection | 12301869 | 44228498 | 44228521 | 19 | + | 28162770 | OCIAML2 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.254747794648833 | [74] | [495] | 2 | hSpCas9 | negative selection | 12301870 | 44228469 | 44228492 | 19 | + | 28162770 | OCIAML2 | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -0.8198652661252589 | [49] | [156] | -5 | hSpCas9 | negative selection | 12301871 | 44228550 | 44228573 | 19 | + | 28162770 | OCIAML2 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | -0.05109093372837645 | [39] | [213] | 0 | hSpCas9 | negative selection | 12301872 | 44217796 | 44217819 | 19 | - | 28162770 | OCIAML2 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | 0.014797001928080533 | [49] | [279] | 0 | hSpCas9 | negative selection | 12301873 | 44228483 | 44228506 | 19 | - | 28162770 | OCIAML2 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.33448314602877316 | [91] | [642] | 3 | hSpCas9 | negative selection | 12301874 | 44217810 | 44217833 | 19 | + | 28162770 | OCIAML2 | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | 0.2949049211208159 | [9] | [67] | 3 | hSpCas9 | negative selection | 12301875 | 44228523 | 44228546 | 19 | + | 28162770 | OCIAML3 | viability | GCTGTACCGAGATGTCATGGTGG | ZNF227 | ENSG00000131115 | 0.4420917003025693 | [147] | [606] | 4 | hSpCas9 | negative selection | 12471234 | 44217817 | 44217840 | 19 | - | 28162770 | OCIAML3 | viability | ATTTTCTCCTGCTTCTTCTGGGG | ZNF227 | ENSG00000131115 | 0.17818644215302437 | [177] | [607] | 1 | hSpCas9 | negative selection | 12471235 | 44228498 | 44228521 | 19 | + | 28162770 | OCIAML3 | viability | GACTGCTCGATCTTACCCAGAGG | ZNF227 | ENSG00000131115 | 0.8654239783131341 | [93] | [516] | 7 | hSpCas9 | negative selection | 12471236 | 44228469 | 44228492 | 19 | + | 28162770 | OCIAML3 | viability | GGCTGTGGTCTTCTCCAGGGAGG | ZNF227 | ENSG00000131115 | -0.16870180559149212 | [69] | [187] | -1 | hSpCas9 | negative selection | 12471237 | 44228550 | 44228573 | 19 | + | 28162770 | OCIAML3 | viability | CTTCAAGAACCTGGTTGCAGTGG | ZNF227 | ENSG00000131115 | 0.513520823980282 | [41] | [180] | 5 | hSpCas9 | negative selection | 12471238 | 44217796 | 44217819 | 19 | - | 28162770 | OCIAML3 | viability | GGAAGGTCATAGTTCTGAGATGG | ZNF227 | ENSG00000131115 | -0.21926284699335258 | [58] | [152] | -2 | hSpCas9 | negative selection | 12471239 | 44228483 | 44228506 | 19 | - | 28162770 | OCIAML3 | viability | GAGCAGTCGCAGTTCCTCCCTGG | ZNF227 | ENSG00000131115 | 0.3458212100932372 | [152] | [586] | 3 | hSpCas9 | negative selection | 12471240 | 44217810 | 44217833 | 19 | + | 28162770 | OCIAML3 | viability | TGACCTTCCCCAGAAGAAGCAGG | ZNF227 | ENSG00000131115 | -0.616033946654162 | [32] | [64] | -5 | hSpCas9 | negative selection | 12471241 |