Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:56242
• Symbol:ZNF253
• Description:zinc finger protein 253

DataSource: http://genomecrispr.dkfz.de/#!/results/ZNF253

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
19880055	19880078	19	+	26472758	Jiyoye	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.4988058569714417	[121]	[129]	4	hSpCas9	negative selection	186395
19891617	19891640	19	+	26472758	Jiyoye	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-1.3622116903527104	[74]	[21]	-7	hSpCas9	negative selection	186396
19891605	19891628	19	+	26472758	Jiyoye	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	0.06837346805411476	[85]	[67]	0	hSpCas9	negative selection	186397
19892133	19892156	19	-	26472758	Jiyoye	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.273319634771083	[236]	[215]	2	hSpCas9	negative selection	186398
19892038	19892061	19	-	26472758	Jiyoye	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	-0.3124490130512698	[633]	[384]	-2	hSpCas9	negative selection	186399
19892290	19892313	19	-	26472758	Jiyoye	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	5.5903972055616435	[2]	[108]	9	hSpCas9	negative selection	186400
19891595	19891618	19	+	26472758	Jiyoye	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.12075617417890394	[61]	[42]	-1	hSpCas9	negative selection	186401
19880074	19880097	19	+	26472758	Jiyoye	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	-0.5424929429439822	[337]	[174]	-4	hSpCas9	negative selection	186402
19891842	19891865	19	+	26472758	Jiyoye	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-1.8840559161585726	[278]	[56]	-8	hSpCas9	negative selection	186403
19892347	19892370	19	-	26472758	Jiyoye	viability	GCCACATTCTCTACATCTGTAGG	ZNF253	ENSG00000256771	-2.223111109724773	[290]	[46]	-8	hSpCas9	negative selection	187954
19891487	19891510	19	+	26472758	Jiyoye	viability	TTTTGCCCAAGACCTTTGGCCAG	ZNF253	ENSG00000256771	-0.08071268318065195	[351]	[250]	0	hSpCas9	negative selection	190323
19880055	19880078	19	+	26472758	KBM7	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.5783808845768815	[338,309]	[229,225]	6	hSpCas9	negative selection	377513
19891617	19891640	19	+	26472758	KBM7	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-1.049022965776592	[440,367]	[43,133]	-7	hSpCas9	negative selection	377514
19891605	19891628	19	+	26472758	KBM7	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	1.2115352426225305	[326,219]	[315,272]	9	hSpCas9	negative selection	377515
19892133	19892156	19	-	26472758	KBM7	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.8943302396329842	[1359,1465]	[1780,766]	8	hSpCas9	negative selection	377516
19892038	19892061	19	-	26472758	KBM7	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.802908356550849	[1512,1118]	[1601,590]	8	hSpCas9	negative selection	377517
19892290	19892313	19	-	26472758	KBM7	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	0.8739385897412197	[658,517]	[354,635]	8	hSpCas9	negative selection	377518
19891595	19891618	19	+	26472758	KBM7	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.6919497514773003	[114,210]	[200,62]	7	hSpCas9	negative selection	377519
19880074	19880097	19	+	26472758	KBM7	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	0.10803698680690332	[1270,1060]	[525,643]	1	hSpCas9	negative selection	377520
19891842	19891865	19	+	26472758	KBM7	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-0.8265234105209143	[818,602]	[195,177]	-6	hSpCas9	negative selection	377521
19892347	19892370	19	-	26472758	KBM7	viability	GCCACATTCTCTACATCTGTAGG	ZNF253	ENSG00000256771	0.09877578260204534	[531,758]	[191,457]	1	hSpCas9	negative selection	379072
19891487	19891510	19	+	26472758	KBM7	viability	TTTTGCCCAAGACCTTTGGCCAG	ZNF253	ENSG00000256771	0.5333145781110231	[1692,1795]	[1338,1068]	6	hSpCas9	negative selection	381441
19880055	19880078	19	+	26472758	Raji	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.4707589148299507	[198]	[63]	4	hSpCas9	negative selection	568631
19891617	19891640	19	+	26472758	Raji	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-1.2780475018199209	[208]	[19]	-7	hSpCas9	negative selection	568632
19891605	19891628	19	+	26472758	Raji	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	0.9374585339312872	[98]	[43]	8	hSpCas9	negative selection	568633
19892133	19892156	19	-	26472758	Raji	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.7150661125948393	[440]	[167]	6	hSpCas9	negative selection	568634
19892038	19892061	19	-	26472758	Raji	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	1.033128980680177	[597]	[283]	8	hSpCas9	negative selection	568635
19892290	19892313	19	-	26472758	Raji	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	0.6843532453412251	[361]	[134]	6	hSpCas9	negative selection	568636
19891595	19891618	19	+	26472758	Raji	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.10738353537359924	[59]	[14]	1	hSpCas9	negative selection	568637
19880074	19880097	19	+	26472758	Raji	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	-0.6066737514825635	[957]	[145]	-5	hSpCas9	negative selection	568638
19891842	19891865	19	+	26472758	Raji	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-1.3817189499400404	[392]	[34]	-7	hSpCas9	negative selection	568639
19892347	19892370	19	-	26472758	Raji	viability	GCCACATTCTCTACATCTGTAGG	ZNF253	ENSG00000256771	-0.5248846801259135	[247]	[39]	-4	hSpCas9	negative selection	570190
19891487	19891510	19	+	26472758	Raji	viability	TTTTGCCCAAGACCTTTGGCCAG	ZNF253	ENSG00000256771	0.041581476977853526	[941]	[224]	0	hSpCas9	negative selection	572559
19880055	19880078	19	+	26472758	K562	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	1.658346034477355	[324]	[865]	9	hSpCas9	negative selection	759749
19891617	19891640	19	+	26472758	K562	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-0.7856385061897327	[193]	[94]	-4	hSpCas9	negative selection	759750
19891605	19891628	19	+	26472758	K562	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	0.8818486482817387	[242]	[377]	7	hSpCas9	negative selection	759751
19892133	19892156	19	-	26472758	K562	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.4218892969253738	[1122]	[1269]	3	hSpCas9	negative selection	759752
19892038	19892061	19	-	26472758	K562	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	1.5677188578839332	[1050]	[2629]	9	hSpCas9	negative selection	759753
19892290	19892313	19	-	26472758	K562	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	1.076919297898229	[519]	[925]	8	hSpCas9	negative selection	759754
19891595	19891618	19	+	26472758	K562	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	1.2193277467036165	[115]	[227]	8	hSpCas9	negative selection	759755
19880074	19880097	19	+	26472758	K562	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	-0.17871018396594485	[1191]	[888]	-1	hSpCas9	negative selection	759756
19891842	19891865	19	+	26472758	K562	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-0.9476000446264821	[657]	[287]	-5	hSpCas9	negative selection	759757
19892347	19892370	19	-	26472758	K562	viability	GCCACATTCTCTACATCTGTAGG	ZNF253	ENSG00000256771	-0.7589016306251646	[434]	[216]	-4	hSpCas9	negative selection	761308
19891487	19891510	19	+	26472758	K562	viability	TTTTGCCCAAGACCTTTGGCCAG	ZNF253	ENSG00000256771	0.46865014866667565	[1343]	[1569]	4	hSpCas9	negative selection	763677
19891585	19891608	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAAAAAGGCTGTAAAAGCGTGGG	ZNF253	ENSG00000256771	-0.688420485511553	[2,2]	[1,0]	-8	hSpCas9	positive selection	3034154
19892335	19892358	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACATCTGTAGGGTTTCTCTCCAG	ZNF253	ENSG00000256771	0.3532860784861286	[4,4]	[3,6]	7	hSpCas9	positive selection	3034155
19891915	19891938	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACATCTGTAGGGTTTCTCTCCGG	ZNF253	ENSG00000256771	0.3532860784861286	[4,4]	[3,6]	7	hSpCas9	positive selection	3034156
19878547	19878570	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGCACAGCGGAATTTATATAGGG	ZNF253	ENSG00000256771	-0.4867197605971055	[3,3]	[1,1]	-6	hSpCas9	positive selection	3034157
19880140	19880163	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTCACTCGTACCTACCTGGGGG	ZNF253	ENSG00000256771	-0.6026882827278734	[3,3]	[2,0]	-7	hSpCas9	positive selection	3034158
19891585	19891608	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAAAAAGGCTGTAAAAGCGTGGG	ZNF253	ENSG00000256771	0.1049569988890843	[2,2]	[1,1]	1	hSpCas9	positive selection	3102012
19892335	19892358	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACATCTGTAGGGTTTCTCTCCAG	ZNF253	ENSG00000256771	-0.4584580540346426	[4,4]	[2,1]	-6	hSpCas9	positive selection	3102013
19891915	19891938	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACATCTGTAGGGTTTCTCTCCGG	ZNF253	ENSG00000256771	-0.4584580540346426	[4,4]	[2,1]	-6	hSpCas9	positive selection	3102014
19878547	19878570	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGCACAGCGGAATTTATATAGGG	ZNF253	ENSG00000256771	-0.26130863720570696	[3,3]	[2,0]	-4	hSpCas9	positive selection	3102015
19880140	19880163	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTCACTCGTACCTACCTGGGGG	ZNF253	ENSG00000256771	-0.09011123042509345	[3,3]	[3,1]	-1	hSpCas9	positive selection	3102016
19880094	19880117		+	24336571	A375	resistance to PLX after 7 days	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.2894606241660602	[1,1]	[2,2]	7	hSpCas9	positive selection	3157221
19880055	19880078		+	24336571	A375	resistance to PLX after 7 days	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	-0.04620420666746017	[15,15]	[14,15]	-1	hSpCas9	positive selection	3157222
19880094	19880117		+	24336571	A375	resistance to PLX after 14 days	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.8000723371963476	[2,1]	[1,1]	6	hSpCas9	positive selection	3215014
19880055	19880078		+	24336571	A375	resistance to PLX after 14 days	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.2427471451381716	[11,9]	[6,4]	2	hSpCas9	positive selection	3215015
19880094	19880117		+	24336571	A375	viability after 7 days	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	-1.011177039519376	[4]	[1,1]	-9	hSpCas9	negative selection	3272807
19880055	19880078		+	24336571	A375	viability after 7 days	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.3764292316420136	[12]	[15,15]	6	hSpCas9	negative selection	3272808
19880094	19880117		+	24336571	A375	viability after 14 days	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	-0.6839553860729051	[4]	[2,1]	-7	hSpCas9	negative selection	3330600
19880055	19880078		+	24336571	A375	viability after 14 days	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	-0.12265211180007789	[12]	[11,9]	-1	hSpCas9	negative selection	3330601
19880094	19880117	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	1.257326211445835	[63,63]	[0,0]	5	hSpCas9	positive selection	3402685
19878537	19878560	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATTCCGCTGTGCAGTGTCCAGG	ZNF253	ENSG00000256771	1.5024387092823666	[53,53]	[0,0]	6	hSpCas9	positive selection	3402686
19891584	19891607	19	+	26780180	HT29	viability (Avana library 4 designs)	AAAAAAGGCTGTAAAAGCGTGGG	ZNF253	ENSG00000256771	2.02394248530052	[]	[]	7	hSpCas9	negative selection	3473478
19892335	19892358	19	-	26780180	HT29	viability (Avana library 4 designs)	ACATCTGTAGGGTTTCTCTCCAG	ZNF253	ENSG00000256771	2.21700089247556	[]	[]	7	hSpCas9	negative selection	3473479
19891915	19891938	19	-	26780180	HT29	viability (Avana library 4 designs)	ACATCTGTAGGGTTTCTCTCCGG	ZNF253	ENSG00000256771	2.21700089247556	[]	[]	7	hSpCas9	negative selection	3473480
19878546	19878569	19	+	26780180	HT29	viability (Avana library 4 designs)	TGCACAGCGGAATTTATATAGGG	ZNF253	ENSG00000256771	2.81923738332667	[]	[]	8	hSpCas9	negative selection	3473481
19880140	19880163	19	-	26780180	HT29	viability (Avana library 4 designs)	TTTCACTCGTACCTACCTGGGGG	ZNF253	ENSG00000256771	2.03517806969024	[]	[]	7	hSpCas9	negative selection	3473482
19880140	19880163	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCACTCGTACCTACCTGGGGG	ZNF253	ENSG00000256771	-12.5092987871837	[]	[]	-8	hSpCas9	negative selection	3581250
19892335	19892358	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACATCTGTAGGGTTTCTCTCCAG	ZNF253	ENSG00000256771	-1.95364295846633	[]	[]	-2	hSpCas9	negative selection	3581251
19891915	19891938	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACATCTGTAGGGTTTCTCTCCGG	ZNF253	ENSG00000256771	-1.95364295846633	[]	[]	-2	hSpCas9	negative selection	3581252
19878546	19878569	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGCACAGCGGAATTTATATAGGG	ZNF253	ENSG00000256771	-1.84817631682359	[]	[]	-2	hSpCas9	negative selection	3581253
19891584	19891607	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAAAAAGGCTGTAAAAGCGTGGG	ZNF253	ENSG00000256771	-5.01805628924969	[]	[]	-5	hSpCas9	negative selection	3581254
19880073	19880096	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTGCTCCAGACAGGTAACCAGG	ZNF253	ENSG00000256771	0.00335360781928501	[]	[]	0	hSpCas9	negative selection	3581255
19891608	19891631	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCATAAGGTGCACAAAGGAGG	ZNF253	ENSG00000256771	1.5491663185287	[]	[]	2	hSpCas9	negative selection	3581256
19880140	19880163	19	-	26780180	A375	viability (Avana lentiGuide)	TTTCACTCGTACCTACCTGGGGG	ZNF253	ENSG00000256771	13.0319540776239	[]	[]	7	hSpCas9	negative selection	3689909
19892335	19892358	19	-	26780180	A375	viability (Avana lentiGuide)	ACATCTGTAGGGTTTCTCTCCAG	ZNF253	ENSG00000256771	11.6629098622555	[]	[]	7	hSpCas9	negative selection	3689910
19891915	19891938	19	-	26780180	A375	viability (Avana lentiGuide)	ACATCTGTAGGGTTTCTCTCCGG	ZNF253	ENSG00000256771	11.6629098622555	[]	[]	7	hSpCas9	negative selection	3689911
19878546	19878569	19	+	26780180	A375	viability (Avana lentiGuide)	TGCACAGCGGAATTTATATAGGG	ZNF253	ENSG00000256771	10.2641060664954	[]	[]	7	hSpCas9	negative selection	3689912
19891584	19891607	19	+	26780180	A375	viability (Avana lentiGuide)	AAAAAAGGCTGTAAAAGCGTGGG	ZNF253	ENSG00000256771	1.41942357759885	[]	[]	1	hSpCas9	negative selection	3689913
19880073	19880096	19	-	26780180	A375	viability (Avana lentiGuide)	CTTGCTCCAGACAGGTAACCAGG	ZNF253	ENSG00000256771	3.04609222415424	[]	[]	3	hSpCas9	negative selection	3689914
19891608	19891631	19	+	26780180	A375	viability (Avana lentiGuide)	GAGCATAAGGTGCACAAAGGAGG	ZNF253	ENSG00000256771	3.4905957662445	[]	[]	3	hSpCas9	negative selection	3689915
19880140	19880163	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCACTCGTACCTACCTGGGGG	ZNF253	ENSG00000256771	-0.9285580136806056	[5]	[2,1]	-8	hSpCas9	positive selection	3798516
19892335	19892358	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACATCTGTAGGGTTTCTCTCCAG	ZNF253	ENSG00000256771	-0.29984934134498537	[6]	[6,3]	-4	hSpCas9	positive selection	3798517
19891915	19891938	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACATCTGTAGGGTTTCTCTCCGG	ZNF253	ENSG00000256771	-0.29984934134498537	[6]	[6,3]	-4	hSpCas9	positive selection	3798518
19878546	19878569	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCACAGCGGAATTTATATAGGG	ZNF253	ENSG00000256771	-0.4353954009891368	[6]	[5,3]	-6	hSpCas9	positive selection	3798519
19891584	19891607	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAAAAAGGCTGTAAAAGCGTGGG	ZNF253	ENSG00000256771	-0.2228635619202392	[5]	[4,3]	-4	hSpCas9	positive selection	3798520
19880073	19880096	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTGCTCCAGACAGGTAACCAGG	ZNF253	ENSG00000256771	0.2902277351013249	[4]	[5,5]	8	hSpCas9	positive selection	3798521
19891608	19891631	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCATAAGGTGCACAAAGGAGG	ZNF253	ENSG00000256771	0.03130525116805202	[5]	[4,6]	0	hSpCas9	positive selection	3798522
19880140	19880163	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCACTCGTACCTACCTGGGGG	ZNF253	ENSG00000256771	-0.4990368392260145	[6]	[1,4]	-6	hSpCas9	positive selection	3907123
19892335	19892358	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACATCTGTAGGGTTTCTCTCCAG	ZNF253	ENSG00000256771	-0.5647698955046802	[7]	[4,3]	-6	hSpCas9	positive selection	3907124
19891915	19891938	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACATCTGTAGGGTTTCTCTCCGG	ZNF253	ENSG00000256771	-0.5647698955046802	[7]	[4,3]	-6	hSpCas9	positive selection	3907125
19878546	19878569	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCACAGCGGAATTTATATAGGG	ZNF253	ENSG00000256771	-1.908063646721387	[5]	[0,0]	-9	hSpCas9	positive selection	3907126
19891584	19891607	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAAAAAGGCTGTAAAAGCGTGGG	ZNF253	ENSG00000256771	-0.157477472546515	[4]	[2,4]	-2	hSpCas9	positive selection	3907127
19880073	19880096	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTGCTCCAGACAGGTAACCAGG	ZNF253	ENSG00000256771	0.33580346933379973	[5]	[5,6]	8	hSpCas9	positive selection	3907128
19891608	19891631	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCATAAGGTGCACAAAGGAGG	ZNF253	ENSG00000256771	0.005069144965254346	[6]	[5,4]	0	hSpCas9	positive selection	3907129
19892122	19892145	19	-	26780180	A375	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.606704311764337	[]	[]	2	hSpCas9	negative selection	4015221
19880094	19880117	19	+	26780180	A375	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	1.38129877480482	[]	[]	7	hSpCas9	negative selection	4015222
19891595	19891618	19	+	26780180	A375	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.764602130558602	[]	[]	3	hSpCas9	negative selection	4015223
19880104	19880127	19	-	26780180	A375	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.554626308582274	[]	[]	1	hSpCas9	negative selection	4015224
19892122	19892145	19	-	26780180	HT29	viability (GeCKOv2 library)	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.9370855315142	[]	[]	4	hSpCas9	negative selection	4123187
19880094	19880117	19	+	26780180	HT29	viability (GeCKOv2 library)	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.943210992475153	[]	[]	4	hSpCas9	negative selection	4123188
19891595	19891618	19	+	26780180	HT29	viability (GeCKOv2 library)	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.788626732034914	[]	[]	3	hSpCas9	negative selection	4123189
19880104	19880127	19	-	26780180	HT29	viability (GeCKOv2 library)	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	1.22094133096716	[]	[]	6	hSpCas9	negative selection	4123190
19880094	19880117	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.05388880140086805	[1]	[0,0]	1	hSpCas9	positive selection	4184253
19880055	19880078	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	-0.06864794504798782	[3]	[1,2]	-2	hSpCas9	positive selection	4184254
19880094	19880117	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.026912299273766038	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4248275
19880055	19880078	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	1.2559514939846337	[3]	[3,4,1,3]	9	hSpCas9	positive selection	4248276
19891595	19891618	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.4665274641388758	[1]	[0,0]	-7	hSpCas9	positive selection	4309288
19880104	19880127	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	-0.11205177855368056	[3]	[3,0]	-2	hSpCas9	positive selection	4309289
19892122	19892145	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.3071467429716301	[2]	[2,2]	6	hSpCas9	positive selection	4309290
19880094	19880117	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	-0.2927447822616485	[1]	[1,0]	-6	hSpCas9	positive selection	4373535
19880104	19880126	19	-	27760321	OCIAML3	viability	CATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	-0.29487310275249357	[30,16]	[4,27]	-3	hSpCas9	negative selection	4456322
19891499	19891521	19	-	27760321	OCIAML3	viability	TTGTATGTTCTCTGGCCAAAGG	ZNF253	ENSG00000256771	0.3327247371079149	[425,423]	[382,467]	4	hSpCas9	negative selection	4456323
19891596	19891618	19	+	27760321	OCIAML3	viability	AAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.24468397140461567	[308,258]	[150,406]	3	hSpCas9	negative selection	4456324
19892038	19892060	19	-	27760321	OCIAML3	viability	AGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	1.1143356945607406	[622,605]	[931,1186]	9	hSpCas9	negative selection	4456325
19892132	19892154	19	-	27760321	OCIAML3	viability	ATGTGTGGTAACGTGTGAGGGG	ZNF253	ENSG00000256771	-0.03793963169251585	[392,331]	[285,260]	0	hSpCas9	negative selection	4456326
19880104	19880126	19	-	27760321	OCIAML2	viability	CATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.18463185554297912	[30,16]	[15,28]	2	hSpCas9	negative selection	4539785
19891499	19891521	19	-	27760321	OCIAML2	viability	TTGTATGTTCTCTGGCCAAAGG	ZNF253	ENSG00000256771	0.0650757792560665	[425,423]	[308,428]	0	hSpCas9	negative selection	4539786
19891596	19891618	19	+	27760321	OCIAML2	viability	AAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.7765003489032213	[308,258]	[350,445]	9	hSpCas9	negative selection	4539787
19892038	19892060	19	-	27760321	OCIAML2	viability	AGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.656464875397001	[622,605]	[688,911]	8	hSpCas9	negative selection	4539788
19892132	19892154	19	-	27760321	OCIAML2	viability	ATGTGTGGTAACGTGTGAGGGG	ZNF253	ENSG00000256771	0.1615943612264499	[392,331]	[290,373]	2	hSpCas9	negative selection	4539789
19880104	19880126	19	-	27760321	MV411	viability	CATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	2.219401049524794	[30,16]	[110,13]	9	hSpCas9	negative selection	4623248
19891499	19891521	19	-	27760321	MV411	viability	TTGTATGTTCTCTGGCCAAAGG	ZNF253	ENSG00000256771	0.3786654430522469	[425,423]	[318,435]	2	hSpCas9	negative selection	4623249
19891596	19891618	19	+	27760321	MV411	viability	AAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.01607345208137867	[308,258]	[145,252]	0	hSpCas9	negative selection	4623250
19892038	19892060	19	-	27760321	MV411	viability	AGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.7628775973073683	[622,605]	[418,1095]	5	hSpCas9	negative selection	4623251
19892132	19892154	19	-	27760321	MV411	viability	ATGTGTGGTAACGTGTGAGGGG	ZNF253	ENSG00000256771	-0.4405530701031569	[392,331]	[207,126]	-3	hSpCas9	negative selection	4623252
19880104	19880126	19	-	27760321	HL60	viability	CATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	1.9966749525496117	[30,16]	[30,124]	9	hSpCas9	negative selection	4706711
19891499	19891521	19	-	27760321	HL60	viability	TTGTATGTTCTCTGGCCAAAGG	ZNF253	ENSG00000256771	0.45771187316706213	[425,423]	[453,503]	5	hSpCas9	negative selection	4706712
19891596	19891618	19	+	27760321	HL60	viability	AAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.33217846041261395	[308,258]	[320,258]	4	hSpCas9	negative selection	4706713
19892038	19892060	19	-	27760321	HL60	viability	AGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.2184783824401716	[622,605]	[528,644]	2	hSpCas9	negative selection	4706714
19892132	19892154	19	-	27760321	HL60	viability	ATGTGTGGTAACGTGTGAGGGG	ZNF253	ENSG00000256771	0.2125122810335266	[392,331]	[436,240]	2	hSpCas9	negative selection	4706715
19880104	19880126	19	-	27760321	HT1080	viability	CATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	-0.20397139330307823	[16,12]	[8,0]	-1	hSpCas9	negative selection	4790174
19891499	19891521	19	-	27760321	HT1080	viability	TTGTATGTTCTCTGGCCAAAGG	ZNF253	ENSG00000256771	-0.637869077187861	[423,330]	[25,173]	-3	hSpCas9	negative selection	4790175
19891596	19891618	19	+	27760321	HT1080	viability	AAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.34587049564110395	[258,201]	[87,54]	-1	hSpCas9	negative selection	4790176
19892038	19892060	19	-	27760321	HT1080	viability	AGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	1.3144377906302427	[605,472]	[671,383]	7	hSpCas9	negative selection	4790177
19892132	19892154	19	-	27760321	HT1080	viability	ATGTGTGGTAACGTGTGAGGGG	ZNF253	ENSG00000256771	1.1381936170850764	[331,258]	[355,152]	6	hSpCas9	negative selection	4790178
19880104	19880126	19	-	27760321	HT29	viability after 7 days	CATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.49200966447755246	[16,12]	[41,2,37]	7	hSpCas9	negative selection	4873637
19891499	19891521	19	-	27760321	HT29	viability after 7 days	TTGTATGTTCTCTGGCCAAAGG	ZNF253	ENSG00000256771	-0.32457699514103555	[423,330]	[431,300,433]	-5	hSpCas9	negative selection	4873638
19891596	19891618	19	+	27760321	HT29	viability after 7 days	AAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.5763794073379828	[258,201]	[551,419,370]	8	hSpCas9	negative selection	4873639
19892038	19892060	19	-	27760321	HT29	viability after 7 days	AGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.033669587767099385	[605,472]	[588,755,764]	0	hSpCas9	negative selection	4873640
19892132	19892154	19	-	27760321	HT29	viability after 7 days	ATGTGTGGTAACGTGTGAGGGG	ZNF253	ENSG00000256771	-0.06942563979103811	[331,258]	[464,261,372]	-1	hSpCas9	negative selection	4873641
19880104	19880126	19	-	27760321	HT29	viability after 25 days	CATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	1.1887877475758772	[16,12]	[52,33,27]	9	hSpCas9	negative selection	4957100
19891499	19891521	19	-	27760321	HT29	viability after 25 days	TTGTATGTTCTCTGGCCAAAGG	ZNF253	ENSG00000256771	-0.2487376940405849	[423,330]	[321,434,330]	-3	hSpCas9	negative selection	4957101
19891596	19891618	19	+	27760321	HT29	viability after 25 days	AAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.7453920066558496	[258,201]	[294,409,649]	8	hSpCas9	negative selection	4957102
19892038	19892060	19	-	27760321	HT29	viability after 25 days	AGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.15517135279387728	[605,472]	[684,891,457]	1	hSpCas9	negative selection	4957103
19892132	19892154	19	-	27760321	HT29	viability after 25 days	ATGTGTGGTAACGTGTGAGGGG	ZNF253	ENSG00000256771	-0.1805355242332018	[331,258]	[281,309,302]	-2	hSpCas9	negative selection	4957104
19880104	19880126	19	-	27760321	HT29	viability after 22 days	CATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.5013975892602378	[16,12]	[38,25,7]	5	hSpCas9	negative selection	5040563
19891499	19891521	19	-	27760321	HT29	viability after 22 days	TTGTATGTTCTCTGGCCAAAGG	ZNF253	ENSG00000256771	0.003311349175029704	[423,330]	[444,432,433]	0	hSpCas9	negative selection	5040564
19891596	19891618	19	+	27760321	HT29	viability after 22 days	AAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.9103597510454999	[258,201]	[437,576,488]	9	hSpCas9	negative selection	5040565
19892038	19892060	19	-	27760321	HT29	viability after 22 days	AGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.1715850083535455	[605,472]	[756,842,503]	1	hSpCas9	negative selection	5040566
19892132	19892154	19	-	27760321	HT29	viability after 22 days	ATGTGTGGTAACGTGTGAGGGG	ZNF253	ENSG00000256771	-0.024111619352583658	[331,258]	[500,202,298]	0	hSpCas9	negative selection	5040567
19880104	19880126	19	-	27760321	HT29	viability after 19 days	CATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	-0.43933468676668763	[16,12]	[30,0,7]	-4	hSpCas9	negative selection	5124026
19891499	19891521	19	-	27760321	HT29	viability after 19 days	TTGTATGTTCTCTGGCCAAAGG	ZNF253	ENSG00000256771	-0.7819612299295771	[423,330]	[310,347,105]	-6	hSpCas9	negative selection	5124027
19891596	19891618	19	+	27760321	HT29	viability after 19 days	AAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.8593079407790635	[258,201]	[659,438,358]	8	hSpCas9	negative selection	5124028
19892038	19892060	19	-	27760321	HT29	viability after 19 days	AGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.2233741970700207	[605,472]	[752,798,615]	2	hSpCas9	negative selection	5124029
19892132	19892154	19	-	27760321	HT29	viability after 19 days	ATGTGTGGTAACGTGTGAGGGG	ZNF253	ENSG00000256771	0.22180801109618098	[331,258]	[316,596,264]	2	hSpCas9	negative selection	5124030
19880104	19880126	19	-	27760321	HT29	viability after 16 days	CATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	-1.6334149411457837	[16,12]	[1,0,12]	-8	hSpCas9	negative selection	5207489
19891499	19891521	19	-	27760321	HT29	viability after 16 days	TTGTATGTTCTCTGGCCAAAGG	ZNF253	ENSG00000256771	0.1036367499003778	[423,330]	[399,655,294]	1	hSpCas9	negative selection	5207490
19891596	19891618	19	+	27760321	HT29	viability after 16 days	AAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.7144887745018079	[258,201]	[341,449,468]	8	hSpCas9	negative selection	5207491
19892038	19892060	19	-	27760321	HT29	viability after 16 days	AGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.479398970175162	[605,472]	[842,1053,621]	5	hSpCas9	negative selection	5207492
19892132	19892154	19	-	27760321	HT29	viability after 16 days	ATGTGTGGTAACGTGTGAGGGG	ZNF253	ENSG00000256771	-0.17380219499140864	[331,258]	[323,296,260]	-2	hSpCas9	negative selection	5207493
19880104	19880126	19	-	27760321	HT29	viability after 13 days	CATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.7925409165262294	[16,12]	[27,60,2]	9	hSpCas9	negative selection	5290952
19891499	19891521	19	-	27760321	HT29	viability after 13 days	TTGTATGTTCTCTGGCCAAAGG	ZNF253	ENSG00000256771	-0.6218977806592114	[423,330]	[252,302,296]	-6	hSpCas9	negative selection	5290953
19891596	19891618	19	+	27760321	HT29	viability after 13 days	AAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.8271191641471718	[258,201]	[494,452,474]	9	hSpCas9	negative selection	5290954
19892038	19892060	19	-	27760321	HT29	viability after 13 days	AGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	-0.2100168010568837	[605,472]	[400,706,516]	-2	hSpCas9	negative selection	5290955
19892132	19892154	19	-	27760321	HT29	viability after 13 days	ATGTGTGGTAACGTGTGAGGGG	ZNF253	ENSG00000256771	-0.16314420037962585	[331,258]	[394,213,308]	-2	hSpCas9	negative selection	5290956
19880104	19880126	19	-	27760321	HT29	viability after 10 days	CATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	-0.24481661942598443	[16,12]	[32,0,12]	-3	hSpCas9	negative selection	5374415
19891499	19891521	19	-	27760321	HT29	viability after 10 days	TTGTATGTTCTCTGGCCAAAGG	ZNF253	ENSG00000256771	-0.24013633186681446	[423,330]	[509,406,282]	-3	hSpCas9	negative selection	5374416
19891596	19891618	19	+	27760321	HT29	viability after 10 days	AAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.6305204031297735	[258,201]	[590,470,278]	8	hSpCas9	negative selection	5374417
19892038	19892060	19	-	27760321	HT29	viability after 10 days	AGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	-0.07924424712999412	[605,472]	[813,584,514]	-1	hSpCas9	negative selection	5374418
19892132	19892154	19	-	27760321	HT29	viability after 10 days	ATGTGTGGTAACGTGTGAGGGG	ZNF253	ENSG00000256771	0.10635582026542892	[331,258]	[400,426,364]	1	hSpCas9	negative selection	5374419
19880104	19880126	19	-	27760321	MOLM13	viability	CATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	1.0362525314421922	[30,16]	[37,17]	7	hSpCas9	negative selection	5457878
19891499	19891521	19	-	27760321	MOLM13	viability	TTGTATGTTCTCTGGCCAAAGG	ZNF253	ENSG00000256771	-0.7359726039186738	[425,423]	[232,68]	-4	hSpCas9	negative selection	5457879
19891596	19891618	19	+	27760321	MOLM13	viability	AAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.4478362135914255	[308,258]	[241,196]	3	hSpCas9	negative selection	5457880
19892038	19892060	19	-	27760321	MOLM13	viability	AGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.9784034879260259	[622,605]	[750,627]	7	hSpCas9	negative selection	5457881
19892132	19892154	19	-	27760321	MOLM13	viability	ATGTGTGGTAACGTGTGAGGGG	ZNF253	ENSG00000256771	-1.7117718386603258	[392,331]	[92,35]	-7	hSpCas9	negative selection	5457882
19866157	19866180	19	+	27661255	K562	viability	GGCGGCTGCGGTGACATCCGGGG	ZNF253	ENSG00000256771	0.19044695631656106	[538,597]	[601,444]	6	dCas9-KRAB	negative selection	5524490
19865904	19865927	19	-	27661255	K562	viability	GGACGGGCCTCTATAAGCACAGG	ZNF253	ENSG00000256771	0.21115718371361658	[635,688]	[682,550]	7	dCas9-KRAB	negative selection	5524491
19865961	19865984	19	-	27661255	K562	viability	GGGGTCCCGGGGTTTAGCTGTGG	ZNF253	ENSG00000256771	-0.11453754632385182	[482,429]	[343,331]	-4	dCas9-KRAB	negative selection	5524492
19891595	19891618	19	+	27260156	BXPC3	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.12062367121372986	[125]	[112,142,133,190]	2	hSpCas9	negative selection	5581748
19880104	19880127	19	-	27260156	BXPC3	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.35488578497394135	[473]	[573,647,617,704]	7	hSpCas9	negative selection	5581749
19892122	19892145	19	-	27260156	BXPC3	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.25523803533358824	[439]	[424,470,626,708]	5	hSpCas9	negative selection	5581750
19880094	19880117	19	+	27260156	BXPC3	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.40341908361676737	[182]	[208,256,336,207]	8	hSpCas9	negative selection	5645995
19891595	19891618	19	+	27260156	A673	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.17368537953424856	[125]	[104,212,83,128]	-4	hSpCas9	negative selection	5702999
19880104	19880127	19	-	27260156	A673	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.31083559605550015	[473]	[809,601,647,781]	7	hSpCas9	negative selection	5703000
19892122	19892145	19	-	27260156	A673	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.22152470047816314	[439]	[650,675,611,520]	5	hSpCas9	negative selection	5703001
19880094	19880117	19	+	27260156	A673	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.052809556798747215	[182]	[219,235,198,256]	1	hSpCas9	negative selection	5767246
19891595	19891618	19	+	27260156	A375	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.407872658749999	[125]	[102,71,162,100]	-5	hSpCas9	negative selection	5824250
19880104	19880127	19	-	27260156	A375	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.5390658387992107	[473]	[921,949,792,595]	7	hSpCas9	negative selection	5824251
19892122	19892145	19	-	27260156	A375	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.4599518589371227	[439]	[629,727,769,699]	6	hSpCas9	negative selection	5824252
19880094	19880117	19	+	27260156	A375	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.325170262570738	[182]	[396,123,298,234]	5	hSpCas9	negative selection	5888497
19891595	19891618	19	+	27260156	COLO741	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.0536861604354506	[125]	[146,129,184]	-1	hSpCas9	negative selection	5945501
19880104	19880127	19	-	27260156	COLO741	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.1984584407042108	[473]	[644,764,670]	4	hSpCas9	negative selection	5945502
19892122	19892145	19	-	27260156	COLO741	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.01969675324374319	[439]	[577,600,532]	0	hSpCas9	negative selection	5945503
19880094	19880117	19	+	27260156	COLO741	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.20173426214791657	[182]	[299,229,277]	4	hSpCas9	negative selection	6009748
19891595	19891618	19	+	27260156	CAL120	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.6777306073054417	[125]	[203,162,375]	8	hSpCas9	negative selection	6066752
19880104	19880127	19	-	27260156	CAL120	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.4808059354654043	[473]	[1255,723,558]	7	hSpCas9	negative selection	6066753
19892122	19892145	19	-	27260156	CAL120	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.11421608648901416	[439]	[898,456,469]	1	hSpCas9	negative selection	6066754
19880094	19880117	19	+	27260156	CAL120	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.5847635684659057	[182]	[427,352,257]	8	hSpCas9	negative selection	6130999
19891595	19891618	19	+	27260156	CADOES1	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.19344628981130585	[125]	[136,139,99,159]	3	hSpCas9	negative selection	6188003
19880104	19880127	19	-	27260156	CADOES1	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.563745822095915	[473]	[554,810,590,649]	8	hSpCas9	negative selection	6188004
19892122	19892145	19	-	27260156	CADOES1	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.33407810905917973	[439]	[547,498,584,427]	5	hSpCas9	negative selection	6188005
19880094	19880117	19	+	27260156	CADOES1	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.20720142314914813	[182]	[175,220,142,247]	3	hSpCas9	negative selection	6252250
19891595	19891618	19	+	27260156	EWS502	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.3026300590288795	[125]	[60,96,180,99]	-5	hSpCas9	negative selection	6309254
19880104	19880127	19	-	27260156	EWS502	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.4544740515304232	[473]	[615,670,686,791]	7	hSpCas9	negative selection	6309255
19892122	19892145	19	-	27260156	EWS502	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.049898026966877944	[439]	[232,581,426,728]	0	hSpCas9	negative selection	6309256
19880094	19880117	19	+	27260156	EWS502	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.10949106126442532	[182]	[87,179,277,313]	2	hSpCas9	negative selection	6373501
19891595	19891618	19	+	27260156	EW8	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.42081393214021046	[125]	[284,61,79,144]	7	hSpCas9	negative selection	6430505
19880104	19880127	19	-	27260156	EW8	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.48959531584892735	[473]	[558,656,418,543]	8	hSpCas9	negative selection	6430506
19892122	19892145	19	-	27260156	EW8	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.36730449283582145	[439]	[518,412,464,446]	6	hSpCas9	negative selection	6430507
19880094	19880117	19	+	27260156	EW8	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	-0.11330113439396028	[182]	[178,145,147,77]	-2	hSpCas9	negative selection	6494752
19891595	19891618	19	+	27260156	CORL105	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.5044892825063865	[125]	[309,150,210,169]	8	hSpCas9	negative selection	6551756
19880104	19880127	19	-	27260156	CORL105	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.27711648880789497	[473]	[599,721,816,569]	5	hSpCas9	negative selection	6551757
19892122	19892145	19	-	27260156	CORL105	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.38112275258138795	[439]	[723,644,735,590]	7	hSpCas9	negative selection	6551758
19880094	19880117	19	+	27260156	CORL105	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.30451290179277146	[182]	[254,207,259,334]	5	hSpCas9	negative selection	6616003
19891595	19891618	19	+	27260156	HS294T	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.2696802149073785	[125]	[43,88,38,63]	3	hSpCas9	negative selection	6673007
19880104	19880127	19	-	27260156	HS294T	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.13342220844168956	[473]	[154,198,167,302]	1	hSpCas9	negative selection	6673008
19892122	19892145	19	-	27260156	HS294T	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.8572528149957847	[439]	[249,372,259,360]	9	hSpCas9	negative selection	6673009
19880094	19880117	19	+	27260156	HS294T	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	-0.2039574810550966	[182]	[62,30,82,70]	-3	hSpCas9	negative selection	6737254
19891595	19891618	19	+	27260156	HCC44	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.26069011472552295	[125]	[138,56,149,143]	-4	hSpCas9	negative selection	6794258
19880104	19880127	19	-	27260156	HCC44	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	-0.05715436802514487	[473]	[610,494,516,447]	-1	hSpCas9	negative selection	6794259
19892122	19892145	19	-	27260156	HCC44	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.12864334923361814	[439]	[603,456,662,487]	2	hSpCas9	negative selection	6794260
19880094	19880117	19	+	27260156	HCC44	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.6893518855206423	[182]	[276,409,446,205]	9	hSpCas9	negative selection	6858505
19891595	19891618	19	+	27260156	G402	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.11161120857881834	[125]	[94,154,217,183]	1	hSpCas9	negative selection	6915509
19880104	19880127	19	-	27260156	G402	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.9300953967312056	[473]	[1452,826,1637,547]	9	hSpCas9	negative selection	6915510
19892122	19892145	19	-	27260156	G402	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.8147493067721121	[439]	[1206,665,1028,895]	8	hSpCas9	negative selection	6915511
19880094	19880117	19	+	27260156	G402	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.4336334421466861	[182]	[245,323,210,411]	5	hSpCas9	negative selection	6979756
19891595	19891618	19	+	27260156	L33	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.024650998271706026	[125]	[122,45,65,171]	0	hSpCas9	negative selection	7036760
19880104	19880127	19	-	27260156	L33	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.01862497029761318	[473]	[527,179,260,535]	0	hSpCas9	negative selection	7036761
19892122	19892145	19	-	27260156	L33	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.1396367938543247	[439]	[494,164,376,441]	3	hSpCas9	negative selection	7036762
19880094	19880117	19	+	27260156	L33	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.30490013133452654	[182]	[189,125,150,167]	6	hSpCas9	negative selection	7101007
19891595	19891618	19	+	27260156	K562	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.2632686665943731	[125]	[108,323,69,50]	3	hSpCas9	negative selection	7158011
19880104	19880127	19	-	27260156	K562	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.5743169187114305	[473]	[658,503,691,641]	7	hSpCas9	negative selection	7158012
19892122	19892145	19	-	27260156	K562	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.8162112664967254	[439]	[535,518,738,905]	9	hSpCas9	negative selection	7158013
19880094	19880117	19	+	27260156	K562	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	-0.4504588005033927	[182]	[246,91,101,50]	-5	hSpCas9	negative selection	7222258
19891595	19891618	19	+	27260156	HT29	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.4949525687239904	[125]	[128,114,64,124]	-7	hSpCas9	negative selection	7279262
19880104	19880127	19	-	27260156	HT29	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.41326965309735864	[473]	[783,751,870,668]	7	hSpCas9	negative selection	7279263
19892122	19892145	19	-	27260156	HT29	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.04624608025547043	[439]	[615,507,500,577]	0	hSpCas9	negative selection	7279264
19880094	19880117	19	+	27260156	HT29	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.26111439742351883	[182]	[289,317,297,175]	5	hSpCas9	negative selection	7343509
19891595	19891618	19	+	27260156	MHHES1	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.28371683675287085	[125]	[215,165,205,116]	5	hSpCas9	negative selection	7400513
19880104	19880127	19	-	27260156	MHHES1	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.5849835911074357	[473]	[1034,724,703,751]	8	hSpCas9	negative selection	7400514
19892122	19892145	19	-	27260156	MHHES1	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.17951347963023362	[439]	[774,694,520,333]	3	hSpCas9	negative selection	7400515
19880094	19880117	19	+	27260156	MHHES1	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.7101270557257631	[182]	[477,433,292,195]	9	hSpCas9	negative selection	7464760
19891595	19891618	19	+	27260156	MEWO	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.26979617711853465	[125]	[117,142,35]	-5	hSpCas9	negative selection	7521764
19880104	19880127	19	-	27260156	MEWO	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.3210354869030723	[473]	[820,459,432]	7	hSpCas9	negative selection	7521765
19892122	19892145	19	-	27260156	MEWO	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.2624576103334249	[439]	[603,407,490]	5	hSpCas9	negative selection	7521766
19880094	19880117	19	+	27260156	MEWO	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.4462450413179976	[182]	[381,144,201]	8	hSpCas9	negative selection	7586011
19891595	19891618	19	+	27260156	LNCAPCLONEFGC	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.2599175028553431	[125]	[81,120,143,39]	-4	hSpCas9	negative selection	7643015
19880104	19880127	19	-	27260156	LNCAPCLONEFGC	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.39179597390088317	[473]	[509,540,707,517]	6	hSpCas9	negative selection	7643016
19892122	19892145	19	-	27260156	LNCAPCLONEFGC	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.30652498859514554	[439]	[384,533,507,545]	5	hSpCas9	negative selection	7643017
19880094	19880117	19	+	27260156	LNCAPCLONEFGC	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.05027776780160376	[182]	[101,272,163,140]	0	hSpCas9	negative selection	7707262
19891595	19891618	19	+	27260156	PANC0327	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.624389810815718	[125]	[199,157,66,268]	8	hSpCas9	negative selection	7764266
19880104	19880127	19	-	27260156	PANC0327	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.7047413592362178	[473]	[779,501,586,906]	8	hSpCas9	negative selection	7764267
19892122	19892145	19	-	27260156	PANC0327	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.27728848857280886	[439]	[655,394,578,289]	4	hSpCas9	negative selection	7764268
19880094	19880117	19	+	27260156	PANC0327	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.7414343817876998	[182]	[349,275,298,167]	9	hSpCas9	negative selection	7828513
19891595	19891618	19	+	27260156	NCIH2009	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.06237513516289783	[125]	[128,200,209]	0	hSpCas9	negative selection	7885517
19880104	19880127	19	-	27260156	NCIH2009	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.557784685478017	[473]	[1238,868,868]	7	hSpCas9	negative selection	7885518
19892122	19892145	19	-	27260156	NCIH2009	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.39418844573589396	[439]	[846,921,658]	5	hSpCas9	negative selection	7885519
19880094	19880117	19	+	27260156	NCIH2009	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.48868225213989125	[182]	[399,348,334]	6	hSpCas9	negative selection	7949764
19891595	19891618	19	+	27260156	NCIH1373	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-1.1258022578226534	[125]	[56,81,58,14]	-8	hSpCas9	negative selection	8006768
19880104	19880127	19	-	27260156	NCIH1373	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.7308896757860109	[473]	[678,496,897,392]	7	hSpCas9	negative selection	8006769
19892122	19892145	19	-	27260156	NCIH1373	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.8196072772316692	[439]	[689,1088,646,265]	7	hSpCas9	negative selection	8006770
19880094	19880117	19	+	27260156	NCIH1373	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.9027607184323931	[182]	[156,183,892,69]	8	hSpCas9	negative selection	8071015
19891595	19891618	19	+	27260156	PATU8902	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.27153608460246415	[125]	[254,86,64,198]	-3	hSpCas9	negative selection	8128019
19880104	19880127	19	-	27260156	PATU8902	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.9014841753505846	[473]	[1629,1028,1001,1326]	8	hSpCas9	negative selection	8128020
19892122	19892145	19	-	27260156	PATU8902	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.8690154514652402	[439]	[1586,663,1223,935]	8	hSpCas9	negative selection	8128021
19880094	19880117	19	+	27260156	PATU8902	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	-0.21826045817435458	[182]	[347,144,157,239]	-2	hSpCas9	negative selection	8192266
19891595	19891618	19	+	27260156	PANC1	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.5617855401865406	[125]	[115,119,116,258]	8	hSpCas9	negative selection	8249270
19880104	19880127	19	-	27260156	PANC1	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.49533377042543303	[473]	[612,475,521,641]	7	hSpCas9	negative selection	8249271
19892122	19892145	19	-	27260156	PANC1	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	-0.07530840085915687	[439]	[349,469,370,274]	-1	hSpCas9	negative selection	8249272
19880094	19880117	19	+	27260156	PANC1	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.2405584782768193	[182]	[121,196,226,195]	4	hSpCas9	negative selection	8313517
19891595	19891618	19	+	27260156	PANC0813	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.10465062958108962	[125]	[221,163,142,34]	-2	hSpCas9	negative selection	8370521
19880104	19880127	19	-	27260156	PANC0813	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.3660358369158795	[473]	[899,637,687,662]	6	hSpCas9	negative selection	8370522
19892122	19892145	19	-	27260156	PANC0813	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.17867001166269836	[439]	[624,571,636,512]	3	hSpCas9	negative selection	8370523
19880094	19880117	19	+	27260156	PANC0813	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.3029470436359418	[182]	[396,261,148,263]	5	hSpCas9	negative selection	8434768
19891595	19891618	19	+	27260156	RDES	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.36780455445310856	[125]	[93,59,125,186]	-6	hSpCas9	negative selection	8491772
19880104	19880127	19	-	27260156	RDES	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.5791165732242147	[473]	[663,778,953,887]	8	hSpCas9	negative selection	8491773
19892122	19892145	19	-	27260156	RDES	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.508072793283909	[439]	[577,661,834,840]	7	hSpCas9	negative selection	8491774
19880094	19880117	19	+	27260156	RDES	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.2485407242180293	[182]	[174,257,286,296]	4	hSpCas9	negative selection	8556019
19891595	19891618	19	+	27260156	PC3	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.0017628360345378624	[125]	[82,240,120,50]	0	hSpCas9	negative selection	8613023
19880104	19880127	19	-	27260156	PC3	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.2609610112486325	[473]	[470,477,931,498]	5	hSpCas9	negative selection	8613024
19892122	19892145	19	-	27260156	PC3	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.12358605529463332	[439]	[204,390,801,742]	2	hSpCas9	negative selection	8613025
19880094	19880117	19	+	27260156	PC3	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.014631471436234778	[182]	[78,253,193,244]	0	hSpCas9	negative selection	8677270
19891595	19891618	19	+	27260156	PATU8988T	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.3795654741914982	[125]	[94,141,82,55]	-6	hSpCas9	negative selection	8734274
19880104	19880127	19	-	27260156	PATU8988T	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.4729422944744279	[473]	[492,637,705,710]	7	hSpCas9	negative selection	8734275
19892122	19892145	19	-	27260156	PATU8988T	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.05861026354623403	[439]	[332,478,610,340]	1	hSpCas9	negative selection	8734276
19880094	19880117	19	+	27260156	PATU8988T	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	-0.17933353920152673	[182]	[153,231,125,116]	-3	hSpCas9	negative selection	8798521
19891595	19891618	19	+	27260156	T47D	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.3461332592181745	[125]	[236,136,144,233]	7	hSpCas9	negative selection	8855525
19880104	19880127	19	-	27260156	T47D	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.5294595985987209	[473]	[835,718,824,814]	9	hSpCas9	negative selection	8855526
19892122	19892145	19	-	27260156	T47D	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.16997829547554782	[439]	[556,476,624,657]	3	hSpCas9	negative selection	8855527
19880094	19880117	19	+	27260156	T47D	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.4427732919515259	[182]	[273,271,261,354]	8	hSpCas9	negative selection	8919772
19891595	19891618	19	+	27260156	SU8686	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.3888176838525077	[125]	[90,55,163,73]	-6	hSpCas9	negative selection	8976776
19880104	19880127	19	-	27260156	SU8686	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.3038041944214271	[473]	[492,474,534,884]	5	hSpCas9	negative selection	8976777
19892122	19892145	19	-	27260156	SU8686	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.47231544830283634	[439]	[488,623,649,676]	7	hSpCas9	negative selection	8976778
19880094	19880117	19	+	27260156	SU8686	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	-0.14241570586911734	[182]	[180,147,165,160]	-3	hSpCas9	negative selection	9041023
19891595	19891618	19	+	27260156	SKES1	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.13382543555511117	[125]	[112,162,101,87]	-3	hSpCas9	negative selection	9098027
19880104	19880127	19	-	27260156	SKES1	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.4267703534334533	[473]	[735,672,659,500]	8	hSpCas9	negative selection	9098028
19892122	19892145	19	-	27260156	SKES1	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.22081191737681122	[439]	[618,424,402,589]	5	hSpCas9	negative selection	9098029
19880094	19880117	19	+	27260156	SKES1	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.4194916963066676	[182]	[277,319,259,141]	8	hSpCas9	negative selection	9162274
19891595	19891618	19	+	27260156	TOV112D	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.2429800476448538	[125]	[103,136,99,92]	-5	hSpCas9	negative selection	9219278
19880104	19880127	19	-	27260156	TOV112D	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.20420519493152228	[473]	[414,724,369,704]	4	hSpCas9	negative selection	9219279
19892122	19892145	19	-	27260156	TOV112D	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.12032508963720873	[439]	[584,468,398,468]	2	hSpCas9	negative selection	9219280
19880094	19880117	19	+	27260156	TOV112D	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.17306675947459982	[182]	[237,159,125,290]	3	hSpCas9	negative selection	9283525
19891595	19891618	19	+	27260156	TC71	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.14492717403772737	[125]	[164,121,86,229]	3	hSpCas9	negative selection	9340529
19880104	19880127	19	-	27260156	TC71	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.2468688307941689	[473]	[531,563,657,660]	6	hSpCas9	negative selection	9340530
19892122	19892145	19	-	27260156	TC71	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.06207327257433449	[439]	[436,545,471,517]	1	hSpCas9	negative selection	9340531
19880094	19880117	19	+	27260156	TC71	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.3446395491485148	[182]	[206,278,210,304]	7	hSpCas9	negative selection	9404776
19891595	19891618	19	+	27260156	TC32	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.33615842737086665	[125]	[81,165,202,148]	6	hSpCas9	negative selection	9461780
19880104	19880127	19	-	27260156	TC32	viability	TCATGTCTTTCCATAGTTAAAGG	ZNF253	ENSG00000256771	0.5279335355971856	[473]	[646,401,885,734]	8	hSpCas9	negative selection	9461781
19892122	19892145	19	-	27260156	TC32	viability	AACGTGTGAGGGGTGCTTAAAGG	ZNF253	ENSG00000256771	0.21659448497558725	[439]	[408,406,564,567]	4	hSpCas9	negative selection	9461782
19880094	19880117	19	+	27260156	TC32	viability	AGGAAAAAAACCTTTAACTATGG	ZNF253	ENSG00000256771	0.14869299370365607	[182]	[190,156,243,179]	2	hSpCas9	negative selection	9526027
19880055	19880078	19	+	28162770	P31FUJ	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.9584221988283899	[126]	[289]	9	hSpCas9	negative selection	10269612
19891617	19891640	19	+	28162770	P31FUJ	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-1.3720769930165062	[162]	[73]	-7	hSpCas9	negative selection	10269613
19891605	19891628	19	+	28162770	P31FUJ	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	0.3972481858353154	[125]	[194]	4	hSpCas9	negative selection	10269614
19892133	19892156	19	-	28162770	P31FUJ	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.8575442976818756	[293]	[625]	8	hSpCas9	negative selection	10269615
19892038	19892061	19	-	28162770	P31FUJ	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.6230626668322812	[446]	[808]	7	hSpCas9	negative selection	10269616
19892290	19892313	19	-	28162770	P31FUJ	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	0.8568350080702978	[272]	[580]	8	hSpCas9	negative selection	10269617
19891595	19891618	19	+	28162770	P31FUJ	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.8631996154629751	[108]	[232]	8	hSpCas9	negative selection	10269618
19880074	19880097	19	+	28162770	P31FUJ	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	0.6687018446470807	[643]	[1202]	7	hSpCas9	negative selection	10269619
19891842	19891865	19	+	28162770	P31FUJ	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-1.3586866448974804	[370]	[169]	-7	hSpCas9	negative selection	10269620
19880055	19880078	19	+	28162770	TF1	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10438978
19891617	19891640	19	+	28162770	TF1	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10438979
19891605	19891628	19	+	28162770	TF1	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10438980
19892133	19892156	19	-	28162770	TF1	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	NaN	[NaN]	[534]	1	hSpCas9	negative selection	10438981
19892038	19892061	19	-	28162770	TF1	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	NaN	[NaN]	[695]	1	hSpCas9	negative selection	10438982
19892290	19892313	19	-	28162770	TF1	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	NaN	[NaN]	[383]	1	hSpCas9	negative selection	10438983
19891595	19891618	19	+	28162770	TF1	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	NaN	[NaN]	[52]	1	hSpCas9	negative selection	10438984
19880074	19880097	19	+	28162770	TF1	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	NaN	[NaN]	[1057]	1	hSpCas9	negative selection	10438985
19891842	19891865	19	+	28162770	TF1	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	NaN	[NaN]	[139]	1	hSpCas9	negative selection	10438986
19880055	19880078	19	+	28162770	SKM1	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.5732995831955763	[45]	[120]	5	hSpCas9	negative selection	10608344
19891617	19891640	19	+	28162770	SKM1	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	0.038595245312578075	[37]	[68]	0	hSpCas9	negative selection	10608345
19891605	19891628	19	+	28162770	SKM1	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	0.27421361723729754	[28]	[61]	2	hSpCas9	negative selection	10608346
19892133	19892156	19	-	28162770	SKM1	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.6361045231487243	[98]	[271]	6	hSpCas9	negative selection	10608347
19892038	19892061	19	-	28162770	SKM1	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.9399926906357228	[119]	[406]	8	hSpCas9	negative selection	10608348
19892290	19892313	19	-	28162770	SKM1	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	1.09737984176971	[45]	[173]	8	hSpCas9	negative selection	10608349
19891595	19891618	19	+	28162770	SKM1	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.3874516676069444	[15]	[36]	4	hSpCas9	negative selection	10608350
19880074	19880097	19	+	28162770	SKM1	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	0.3747990094117015	[129]	[297]	3	hSpCas9	negative selection	10608351
19891842	19891865	19	+	28162770	SKM1	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-0.22589863969564905	[85]	[129]	-2	hSpCas9	negative selection	10608352
19880055	19880078	19	+	28162770	SKM1	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.5732995831955763	[45]	[120]	5	hSpCas9	negative selection	10777710
19891617	19891640	19	+	28162770	SKM1	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	0.038595245312578075	[37]	[68]	0	hSpCas9	negative selection	10777711
19891605	19891628	19	+	28162770	SKM1	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	0.27421361723729754	[28]	[61]	2	hSpCas9	negative selection	10777712
19892133	19892156	19	-	28162770	SKM1	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.6361045231487243	[98]	[271]	6	hSpCas9	negative selection	10777713
19892038	19892061	19	-	28162770	SKM1	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.9399926906357228	[119]	[406]	8	hSpCas9	negative selection	10777714
19892290	19892313	19	-	28162770	SKM1	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	1.09737984176971	[45]	[173]	8	hSpCas9	negative selection	10777715
19891595	19891618	19	+	28162770	SKM1	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.3874516676069444	[15]	[36]	4	hSpCas9	negative selection	10777716
19880074	19880097	19	+	28162770	SKM1	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	0.3747990094117015	[129]	[297]	3	hSpCas9	negative selection	10777717
19891842	19891865	19	+	28162770	SKM1	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-0.22589863969564905	[85]	[129]	-2	hSpCas9	negative selection	10777718
19880055	19880078	19	+	28162770	PL21	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	-0.8823225457026529	[143]	[33]	-6	hSpCas9	negative selection	10947076
19891617	19891640	19	+	28162770	PL21	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-0.47573138243004653	[130]	[40]	-3	hSpCas9	negative selection	10947077
19891605	19891628	19	+	28162770	PL21	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	0.503920362666423	[127]	[78]	4	hSpCas9	negative selection	10947078
19892133	19892156	19	-	28162770	PL21	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	-0.13736128431850314	[325]	[128]	-1	hSpCas9	negative selection	10947079
19892038	19892061	19	-	28162770	PL21	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.5436238527431299	[464]	[294]	5	hSpCas9	negative selection	10947080
19892290	19892313	19	-	28162770	PL21	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	0.6062989624217112	[162]	[107]	5	hSpCas9	negative selection	10947081
19891595	19891618	19	+	28162770	PL21	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.12975028659792232	[62]	[29]	1	hSpCas9	negative selection	10947082
19880074	19880097	19	+	28162770	PL21	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	0.4709235199280486	[556]	[335]	4	hSpCas9	negative selection	10947083
19891842	19891865	19	+	28162770	PL21	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	0.6455507628116826	[234]	[159]	5	hSpCas9	negative selection	10947084
19880055	19880078	19	+	28162770	P31FUJ	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.9584221988283899	[126]	[289]	9	hSpCas9	negative selection	11116442
19891617	19891640	19	+	28162770	P31FUJ	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-1.3720769930165062	[162]	[73]	-7	hSpCas9	negative selection	11116443
19891605	19891628	19	+	28162770	P31FUJ	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	0.3972481858353154	[125]	[194]	4	hSpCas9	negative selection	11116444
19892133	19892156	19	-	28162770	P31FUJ	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.8575442976818756	[293]	[625]	8	hSpCas9	negative selection	11116445
19892038	19892061	19	-	28162770	P31FUJ	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.6230626668322812	[446]	[808]	7	hSpCas9	negative selection	11116446
19892290	19892313	19	-	28162770	P31FUJ	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	0.8568350080702978	[272]	[580]	8	hSpCas9	negative selection	11116447
19891595	19891618	19	+	28162770	P31FUJ	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.8631996154629751	[108]	[232]	8	hSpCas9	negative selection	11116448
19880074	19880097	19	+	28162770	P31FUJ	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	0.6687018446470807	[643]	[1202]	7	hSpCas9	negative selection	11116449
19891842	19891865	19	+	28162770	P31FUJ	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-1.3586866448974804	[370]	[169]	-7	hSpCas9	negative selection	11116450
19880055	19880078	19	+	28162770	OCIAML5	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.2410428335274846	[89]	[191]	2	hSpCas9	negative selection	11285808
19891617	19891640	19	+	28162770	OCIAML5	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-1.9635748860809872	[120]	[55]	-8	hSpCas9	negative selection	11285809
19891605	19891628	19	+	28162770	OCIAML5	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	-0.5368643391649478	[85]	[106]	-4	hSpCas9	negative selection	11285810
19892133	19892156	19	-	28162770	OCIAML5	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.5048213623771655	[211]	[542]	4	hSpCas9	negative selection	11285811
19892038	19892061	19	-	28162770	OCIAML5	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.018115188649046043	[336]	[615]	0	hSpCas9	negative selection	11285812
19892290	19892313	19	-	28162770	OCIAML5	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	0.21206376655571857	[142]	[298]	1	hSpCas9	negative selection	11285813
19891595	19891618	19	+	28162770	OCIAML5	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	1.0833931769412926	[39]	[152]	8	hSpCas9	negative selection	11285814
19880074	19880097	19	+	28162770	OCIAML5	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	0.38096847443295356	[327]	[770]	3	hSpCas9	negative selection	11285815
19891842	19891865	19	+	28162770	OCIAML5	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-0.17246719600476554	[117]	[188]	-1	hSpCas9	negative selection	11285816
19880055	19880078	19	+	28162770	EOL1	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.44650047476589017	[311]	[223]	4	hSpCas9	negative selection	11455174
19891617	19891640	19	+	28162770	EOL1	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-1.1110761381601866	[163]	[39]	-6	hSpCas9	negative selection	11455175
19891605	19891628	19	+	28162770	EOL1	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	-0.8451546090076711	[207]	[60]	-5	hSpCas9	negative selection	11455176
19892133	19892156	19	-	28162770	EOL1	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.4663199035586749	[598]	[435]	4	hSpCas9	negative selection	11455177
19892038	19892061	19	-	28162770	EOL1	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.514957837131361	[792]	[596]	4	hSpCas9	negative selection	11455178
19892290	19892313	19	-	28162770	EOL1	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	0.9749527250077776	[224]	[232]	8	hSpCas9	negative selection	11455179
19891595	19891618	19	+	28162770	EOL1	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.7857200668732177	[108]	[98]	7	hSpCas9	negative selection	11455180
19880074	19880097	19	+	28162770	EOL1	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	0.5103155723633335	[596]	[447]	4	hSpCas9	negative selection	11455181
19891842	19891865	19	+	28162770	EOL1	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-0.0676327239701662	[367]	[184]	0	hSpCas9	negative selection	11455182
19880055	19880078	19	+	28162770	MOLM13	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.7409078759509947	[263]	[318]	5	hSpCas9	negative selection	11624540
19891617	19891640	19	+	28162770	MOLM13	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-1.510736967662854	[200]	[50]	-6	hSpCas9	negative selection	11624541
19891605	19891628	19	+	28162770	MOLM13	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	-0.25934467460385413	[196]	[118]	-1	hSpCas9	negative selection	11624542
19892133	19892156	19	-	28162770	MOLM13	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.8394169902697566	[445]	[576]	6	hSpCas9	negative selection	11624543
19892038	19892061	19	-	28162770	MOLM13	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	1.79124282979098	[606]	[1518]	9	hSpCas9	negative selection	11624544
19892290	19892313	19	-	28162770	MOLM13	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	0.8381389590765846	[228]	[295]	6	hSpCas9	negative selection	11624545
19891595	19891618	19	+	28162770	MOLM13	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	2.1206945280467866	[89]	[282]	9	hSpCas9	negative selection	11624546
19880074	19880097	19	+	28162770	MOLM13	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	0.6943051961422189	[664]	[777]	5	hSpCas9	negative selection	11624547
19891842	19891865	19	+	28162770	MOLM13	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-0.8501863878471769	[373]	[149]	-5	hSpCas9	negative selection	11624548
19880055	19880078	19	+	28162770	HEL	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.9994945154408079	[220]	[282]	8	hSpCas9	negative selection	11793906
19891617	19891640	19	+	28162770	HEL	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-1.320735291974529	[194]	[49]	-6	hSpCas9	negative selection	11793907
19891605	19891628	19	+	28162770	HEL	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	1.1317769127229775	[113]	[159]	8	hSpCas9	negative selection	11793908
19892133	19892156	19	-	28162770	HEL	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	1.7472493209665636	[385]	[829]	9	hSpCas9	negative selection	11793909
19892038	19892061	19	-	28162770	HEL	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.8865561003820301	[591]	[700]	7	hSpCas9	negative selection	11793910
19892290	19892313	19	-	28162770	HEL	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	1.2085290234466672	[201]	[298]	9	hSpCas9	negative selection	11793911
19891595	19891618	19	+	28162770	HEL	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	1.5340325725578572	[61]	[114]	9	hSpCas9	negative selection	11793912
19880074	19880097	19	+	28162770	HEL	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	0.319661637059502	[627]	[501]	2	hSpCas9	negative selection	11793913
19891842	19891865	19	+	28162770	HEL	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-1.0296865099711385	[305]	[95]	-6	hSpCas9	negative selection	11793914
19880055	19880078	19	+	28162770	MV411	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	-0.05286773240479187	[148]	[120]	0	hSpCas9	negative selection	11963272
19891617	19891640	19	+	28162770	MV411	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-2.464057355867313	[130]	[19]	-8	hSpCas9	negative selection	11963273
19891605	19891628	19	+	28162770	MV411	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	1.9510445480025504	[104]	[341]	9	hSpCas9	negative selection	11963274
19892133	19892156	19	-	28162770	MV411	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	1.638101454709022	[290]	[762]	9	hSpCas9	negative selection	11963275
19892038	19892061	19	-	28162770	MV411	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.5544923691886072	[467]	[578]	5	hSpCas9	negative selection	11963276
19892290	19892313	19	-	28162770	MV411	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	0.45334184933065413	[175]	[202]	4	hSpCas9	negative selection	11963277
19891595	19891618	19	+	28162770	MV411	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.5774757426591335	[61]	[34]	-4	hSpCas9	negative selection	11963278
19880074	19880097	19	+	28162770	MV411	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	0.47541266565538787	[478]	[560]	4	hSpCas9	negative selection	11963279
19891842	19891865	19	+	28162770	MV411	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-0.9962315301840876	[295]	[124]	-6	hSpCas9	negative selection	11963280
19880055	19880078	19	+	28162770	MONOMAC1	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	1.2454813886413971	[116]	[317]	9	hSpCas9	negative selection	12132638
19891617	19891640	19	+	28162770	MONOMAC1	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	0.4810350580530839	[89]	[143]	5	hSpCas9	negative selection	12132639
19891605	19891628	19	+	28162770	MONOMAC1	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	0.440393073555738	[80]	[125]	4	hSpCas9	negative selection	12132640
19892133	19892156	19	-	28162770	MONOMAC1	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.9207409529574262	[240]	[522]	8	hSpCas9	negative selection	12132641
19892038	19892061	19	-	28162770	MONOMAC1	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.6673755591412709	[300]	[547]	6	hSpCas9	negative selection	12132642
19892290	19892313	19	-	28162770	MONOMAC1	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	0.05392472647366517	[99]	[118]	0	hSpCas9	negative selection	12132643
19891595	19891618	19	+	28162770	MONOMAC1	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	-0.6824636742297956	[48]	[34]	-5	hSpCas9	negative selection	12132644
19880074	19880097	19	+	28162770	MONOMAC1	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	0.22579601297324614	[322]	[432]	2	hSpCas9	negative selection	12132645
19891842	19891865	19	+	28162770	MONOMAC1	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-0.931512889200062	[192]	[115]	-6	hSpCas9	negative selection	12132646
19880055	19880078	19	+	28162770	OCIAML2	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	0.3714905149761193	[40]	[293]	3	hSpCas9	negative selection	12302004
19891617	19891640	19	+	28162770	OCIAML2	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-0.5580926664925008	[16]	[63]	-4	hSpCas9	negative selection	12302005
19891605	19891628	19	+	28162770	OCIAML2	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	0.2597631150005588	[21]	[145]	2	hSpCas9	negative selection	12302006
19892133	19892156	19	-	28162770	OCIAML2	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.901755695214727	[58]	[610]	8	hSpCas9	negative selection	12302007
19892038	19892061	19	-	28162770	OCIAML2	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	0.7470709007695647	[65]	[613]	7	hSpCas9	negative selection	12302008
19892290	19892313	19	-	28162770	OCIAML2	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	0.20866005802714815	[36]	[236]	2	hSpCas9	negative selection	12302009
19891595	19891618	19	+	28162770	OCIAML2	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.3367250968154427	[12]	[90]	3	hSpCas9	negative selection	12302010
19880074	19880097	19	+	28162770	OCIAML2	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	0.7959133663687712	[76]	[740]	7	hSpCas9	negative selection	12302011
19891842	19891865	19	+	28162770	OCIAML2	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-0.6821339304358729	[32]	[113]	-5	hSpCas9	negative selection	12302012
19880055	19880078	19	+	28162770	OCIAML3	viability	TGTTGTCTCTAAGCCAGACCTGG	ZNF253	ENSG00000256771	-0.3122366719087835	[50]	[123]	-2	hSpCas9	negative selection	12471370
19891617	19891640	19	+	28162770	OCIAML3	viability	GTGCACAAAGGAGGTTATAATGG	ZNF253	ENSG00000256771	-0.4627631070459108	[41]	[91]	-4	hSpCas9	negative selection	12471371
19891605	19891628	19	+	28162770	OCIAML3	viability	GGTGAGCATAAGGTGCACAAAGG	ZNF253	ENSG00000256771	-0.8757786087395427	[30]	[50]	-6	hSpCas9	negative selection	12471372
19892133	19892156	19	-	28162770	OCIAML3	viability	TTATGTGTGGTAACGTGTGAGGG	ZNF253	ENSG00000256771	0.5450563974133885	[83]	[369]	5	hSpCas9	negative selection	12471373
19892038	19892061	19	-	28162770	OCIAML3	viability	AAGGTCTGTGGATCGGTTGAAGG	ZNF253	ENSG00000256771	-0.04678723359455805	[141]	[414]	0	hSpCas9	negative selection	12471374
19892290	19892313	19	-	28162770	OCIAML3	viability	AAGGTGTGAGGATAGGTGAAAGG	ZNF253	ENSG00000256771	0.6919635767867897	[64]	[316]	6	hSpCas9	negative selection	12471375
19891595	19891618	19	+	28162770	OCIAML3	viability	TAAAAGCGTGGGTGAGCATAAGG	ZNF253	ENSG00000256771	0.7752261693415559	[23]	[123]	7	hSpCas9	negative selection	12471376
19880074	19880097	19	+	28162770	OCIAML3	viability	CTGGTTACCTGTCTGGAGCAAGG	ZNF253	ENSG00000256771	-0.11301305946918205	[162]	[454]	-1	hSpCas9	negative selection	12471377
19891842	19891865	19	+	28162770	OCIAML3	viability	CCTTACAGATGTGAAGAATGTGG	ZNF253	ENSG00000256771	-0.9393361677916024	[100]	[158]	-6	hSpCas9	negative selection	12471378