| 112295943 | 112295966 | 7 | - | 26472758 | Jiyoye | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 2.6201691048400715 | [10] | [50] | 9 | hSpCas9 | negative selection | 186526 | 112286947 | 112286970 | 7 | - | 26472758 | Jiyoye | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | 1.4637589098722408 | [49] | [103] | 8 | hSpCas9 | negative selection | 186527 | 112206717 | 112206740 | 7 | + | 26472758 | Jiyoye | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | 0.8701473578484192 | [110] | [152] | 6 | hSpCas9 | negative selection | 186528 | 112206770 | 112206793 | 7 | + | 26472758 | Jiyoye | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | 1.8926022086761154 | [34] | [97] | 8 | hSpCas9 | negative selection | 186529 | 112206750 | 112206773 | 7 | + | 26472758 | Jiyoye | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | 0.08171847513826469 | [306] | [244] | 0 | hSpCas9 | negative selection | 186530 | 112286927 | 112286950 | 7 | - | 26472758 | Jiyoye | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.6612210041124127 | [321] | [383] | 5 | hSpCas9 | negative selection | 186531 | 112296290 | 112296313 | 7 | + | 26472758 | Jiyoye | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 1.511512041320609 | [59] | [128] | 8 | hSpCas9 | negative selection | 186532 | 112286896 | 112286919 | 7 | - | 26472758 | Jiyoye | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | -0.5222055438006046 | [298] | [156] | -4 | hSpCas9 | negative selection | 186533 | 112295943 | 112295966 | 7 | - | 26472758 | KBM7 | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.6053669758027851 | [203,140] | [136,107] | 6 | hSpCas9 | negative selection | 377644 | 112286947 | 112286970 | 7 | - | 26472758 | KBM7 | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | 0.03871579490005228 | [177,298] | [151,88] | 0 | hSpCas9 | negative selection | 377645 | 112206717 | 112206740 | 7 | + | 26472758 | KBM7 | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | 0.620261921294704 | [693,466] | [380,441] | 6 | hSpCas9 | negative selection | 377646 | 112206770 | 112206793 | 7 | + | 26472758 | KBM7 | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | 0.7453431073384703 | [378,302] | [360,182] | 7 | hSpCas9 | negative selection | 377647 | 112206750 | 112206773 | 7 | + | 26472758 | KBM7 | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | 0.14564704999603362 | [1047,1227] | [616,583] | 1 | hSpCas9 | negative selection | 377648 | 112286927 | 112286950 | 7 | - | 26472758 | KBM7 | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | -0.08358121360964987 | [1473,1076] | [517,596] | -1 | hSpCas9 | negative selection | 377649 | 112296290 | 112296313 | 7 | + | 26472758 | KBM7 | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 0.46197848347173304 | [372,503] | [313,267] | 5 | hSpCas9 | negative selection | 377650 | 112286896 | 112286919 | 7 | - | 26472758 | KBM7 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | 0.4458103913358894 | [1058,768] | [555,598] | 5 | hSpCas9 | negative selection | 377651 | 112295943 | 112295966 | 7 | - | 26472758 | Raji | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 1.8249838046728746 | [44] | [36] | 9 | hSpCas9 | negative selection | 568762 | 112286947 | 112286970 | 7 | - | 26472758 | Raji | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | -1.1150088859628486 | [139] | [14] | -7 | hSpCas9 | negative selection | 568763 | 112206717 | 112206740 | 7 | + | 26472758 | Raji | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | 1.1605541943949371 | [292] | [151] | 8 | hSpCas9 | negative selection | 568764 | 112206770 | 112206793 | 7 | + | 26472758 | Raji | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | 1.7506900223255606 | [104] | [81] | 9 | hSpCas9 | negative selection | 568765 | 112206750 | 112206773 | 7 | + | 26472758 | Raji | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | 0.036500049217089714 | [583] | [138] | 0 | hSpCas9 | negative selection | 568766 | 112286927 | 112286950 | 7 | - | 26472758 | Raji | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | -0.015511153608819495 | [844] | [193] | 0 | hSpCas9 | negative selection | 568767 | 112296290 | 112296313 | 7 | + | 26472758 | Raji | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 0.8457983461768754 | [198] | [82] | 7 | hSpCas9 | negative selection | 568768 | 112286896 | 112286919 | 7 | - | 26472758 | Raji | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | 0.062018231164678195 | [742] | [179] | 0 | hSpCas9 | negative selection | 568769 | 112295943 | 112295966 | 7 | - | 26472758 | K562 | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | -0.6249971625234088 | [189] | [103] | -4 | hSpCas9 | negative selection | 759880 | 112286947 | 112286970 | 7 | - | 26472758 | K562 | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | 0.4954351575673176 | [220] | [262] | 4 | hSpCas9 | negative selection | 759881 | 112206717 | 112206740 | 7 | + | 26472758 | K562 | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | -0.0333449580836126 | [570] | [470] | 0 | hSpCas9 | negative selection | 759882 | 112206770 | 112206793 | 7 | + | 26472758 | K562 | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | 1.0554493078674494 | [223] | [392] | 8 | hSpCas9 | negative selection | 759883 | 112206750 | 112206773 | 7 | + | 26472758 | K562 | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | 0.37831626318397915 | [873] | [958] | 3 | hSpCas9 | negative selection | 759884 | 112286927 | 112286950 | 7 | - | 26472758 | K562 | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.43776261649239623 | [1289] | [1474] | 3 | hSpCas9 | negative selection | 759885 | 112296290 | 112296313 | 7 | + | 26472758 | K562 | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 1.8249077518082952 | [322] | [965] | 9 | hSpCas9 | negative selection | 759886 | 112286896 | 112286919 | 7 | - | 26472758 | K562 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | 0.1199562259843594 | [858] | [787] | 0 | hSpCas9 | negative selection | 759887 | 112206716 | 112206739 | 7 | + | 24336569 | HL60 | viability | AATGGCTGCTTCCAAGACCCAGG | ZNF277 | ENSG00000198839 | 0.32690966836893653 | [216] | [575] | 3 | hSpCas9 | negative selection | 2309862 | 112206748 | 112206771 | 7 | - | 24336569 | HL60 | viability | ATCACGGTCTTCCTGCATTCGGG | ZNF277 | ENSG00000198839 | -0.5472515732732915 | [1108] | [1605] | -5 | hSpCas9 | negative selection | 2309863 | 112206764 | 112206787 | 7 | - | 24336569 | HL60 | viability | CTGTGCTGCAGCTCCCATCACGG | ZNF277 | ENSG00000198839 | 0.10741905851730049 | [335] | [765] | 1 | hSpCas9 | negative selection | 2309864 | 112206769 | 112206792 | 7 | + | 24336569 | HL60 | viability | ATGGGAGCTGCAGCACAGTCGGG | ZNF277 | ENSG00000198839 | -0.002500752734039935 | [1421] | [3003] | 0 | hSpCas9 | negative selection | 2309865 | 112286859 | 112286882 | 7 | + | 24336569 | HL60 | viability | TTGGTCTATTCCAGACAGTAAGG | ZNF277 | ENSG00000198839 | -0.5099418568464482 | [682] | [1014] | -4 | hSpCas9 | negative selection | 2309866 | 112286869 | 112286892 | 7 | - | 24336569 | HL60 | viability | AGGATACAATCCTTACTGTCTGG | ZNF277 | ENSG00000198839 | -0.23838268448806266 | [489] | [878] | -2 | hSpCas9 | negative selection | 2309867 | 112286889 | 112286912 | 7 | - | 24336569 | HL60 | viability | CTGGCAGGGAAAGCGGCTCCAGG | ZNF277 | ENSG00000198839 | -0.3426014712900925 | [455] | [760] | -3 | hSpCas9 | negative selection | 2309868 | 112286896 | 112286919 | 7 | - | 24336569 | HL60 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | -0.7958113921330837 | [442] | [539] | -6 | hSpCas9 | negative selection | 2309869 | 112286902 | 112286925 | 7 | + | 24336569 | HL60 | viability | TCCCTGCCAGAAAGTCCAGGTGG | ZNF277 | ENSG00000198839 | -0.42274514995466994 | [393] | [621] | -4 | hSpCas9 | negative selection | 2309870 | 112286908 | 112286931 | 7 | - | 24336569 | HL60 | viability | GTGGTGCCACCTGGACTTTCTGG | ZNF277 | ENSG00000198839 | 0.12755499298783743 | [448] | [1037] | 1 | hSpCas9 | negative selection | 2309871 | 112206716 | 112206739 | 7 | + | 24336569 | KBM7 | viability | AATGGCTGCTTCCAAGACCCAGG | ZNF277 | ENSG00000198839 | -0.4911684650965653 | [251] | [488] | -4 | hSpCas9 | negative selection | 2377039 | 112206748 | 112206771 | 7 | - | 24336569 | KBM7 | viability | ATCACGGTCTTCCTGCATTCGGG | ZNF277 | ENSG00000198839 | 0.006596696636919641 | [699] | [1917] | 0 | hSpCas9 | negative selection | 2377040 | 112206764 | 112206787 | 7 | - | 24336569 | KBM7 | viability | CTGTGCTGCAGCTCCCATCACGG | ZNF277 | ENSG00000198839 | 0.18082859413717822 | [337] | [1044] | 1 | hSpCas9 | negative selection | 2377041 | 112206769 | 112206792 | 7 | + | 24336569 | KBM7 | viability | ATGGGAGCTGCAGCACAGTCGGG | ZNF277 | ENSG00000198839 | -0.007067400133133672 | [1248] | [3389] | 0 | hSpCas9 | negative selection | 2377042 | 112286859 | 112286882 | 7 | + | 24336569 | KBM7 | viability | TTGGTCTATTCCAGACAGTAAGG | ZNF277 | ENSG00000198839 | 0.30535687147302876 | [547] | [1846] | 3 | hSpCas9 | negative selection | 2377043 | 112286869 | 112286892 | 7 | - | 24336569 | KBM7 | viability | AGGATACAATCCTTACTGTCTGG | ZNF277 | ENSG00000198839 | -0.38916251032356053 | [241] | [503] | -3 | hSpCas9 | negative selection | 2377044 | 112286889 | 112286912 | 7 | - | 24336569 | KBM7 | viability | CTGGCAGGGAAAGCGGCTCCAGG | ZNF277 | ENSG00000198839 | -0.9967265628003683 | [367] | [502] | -6 | hSpCas9 | negative selection | 2377045 | 112286896 | 112286919 | 7 | - | 24336569 | KBM7 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | -2.2210706667402027 | [199] | [116] | -8 | hSpCas9 | negative selection | 2377046 | 112286902 | 112286925 | 7 | + | 24336569 | KBM7 | viability | TCCCTGCCAGAAAGTCCAGGTGG | ZNF277 | ENSG00000198839 | 0.2627810410351541 | [300] | [984] | 2 | hSpCas9 | negative selection | 2377047 | 112286908 | 112286931 | 7 | - | 24336569 | KBM7 | viability | GTGGTGCCACCTGGACTTTCTGG | ZNF277 | ENSG00000198839 | 0.9027659557545616 | [371] | [1896] | 7 | hSpCas9 | negative selection | 2377048 | 112285117 | 112285140 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GAGAATTGCTTGAACCCAGGTGG | ZNF277 | ENSG00000198839 | 0.059142044687262585 | [6,100] | [1,23] | 0 | dCas9-VP64 | positive selection | 2407420 | 112218097 | 112218120 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GAGTTTAATTCATGCAGAGCCAG | ZNF277 | ENSG00000198839 | 2.7667599450462554 | [27,57] | [83,45] | 8 | dCas9-VP64 | positive selection | 2419826 | 112206566 | 112206589 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TTTTACTGATTGCGTCCTATTGG | ZNF277 | ENSG00000198839 | -1.5309931704147812 | [579,385] | [37,33] | -8 | dCas9-VP64 | positive selection | 2444818 | 112260220 | 112260243 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CACACCACTGCACTCCACCCTAG | ZNF277 | ENSG00000198839 | 0.5698625377834631 | [32,68] | [24,6] | 2 | dCas9-VP64 | positive selection | 2464490 | 112285117 | 112285140 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GAGAATTGCTTGAACCCAGGTGG | ZNF277 | ENSG00000198839 | 0.5790361197083687 | [35,47] | [19,19] | 4 | dCas9-VP64 | positive selection | 2502675 | 112218097 | 112218120 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GAGTTTAATTCATGCAGAGCCAG | ZNF277 | ENSG00000198839 | 0.021863734013882766 | [98,128] | [43,30] | 0 | dCas9-VP64 | positive selection | 2515081 | 112206566 | 112206589 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TTTTACTGATTGCGTCCTATTGG | ZNF277 | ENSG00000198839 | 0.23596277408321553 | [277,123] | [105,50] | 2 | dCas9-VP64 | positive selection | 2540073 | 112260220 | 112260243 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CACACCACTGCACTCCACCCTAG | ZNF277 | ENSG00000198839 | 0.3041547942409779 | [418,385] | [115,204] | 2 | dCas9-VP64 | positive selection | 2559745 | 112295951 | 112295974 | 7 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CAAGATGTACACTTACCAAATGG | ZNF277 | ENSG00000198839 | 0.17436445507378956 | [4,4] | [4,3] | 3 | hSpCas9 | positive selection | 3034213 | 112206720 | 112206743 | 7 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GGCTGCTTCCAAGACCCAGGGGG | ZNF277 | ENSG00000198839 | -0.3747425965163047 | [3,2] | [3,0] | -5 | hSpCas9 | positive selection | 3034214 | 112286903 | 112286926 | 7 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TCCCTGCCAGAAAGTCCAGGTGG | ZNF277 | ENSG00000198839 | -0.24834415276919083 | [3,3] | [2,2] | -4 | hSpCas9 | positive selection | 3034215 | 112286927 | 112286950 | 7 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | -0.43370114602304627 | [3,3] | [2,1] | -6 | hSpCas9 | positive selection | 3034216 | 112295951 | 112295974 | 7 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CAAGATGTACACTTACCAAATGG | ZNF277 | ENSG00000198839 | 0.3280988314920013 | [4,4] | [5,3] | 6 | hSpCas9 | positive selection | 3102071 | 112206720 | 112206743 | 7 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GGCTGCTTCCAAGACCCAGGGGG | ZNF277 | ENSG00000198839 | 0.1969594412616879 | [3,3] | [1,3] | 3 | hSpCas9 | positive selection | 3102072 | 112286903 | 112286926 | 7 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TCCCTGCCAGAAAGTCCAGGTGG | ZNF277 | ENSG00000198839 | 0.023241391001767336 | [3,3] | [3,1] | 0 | hSpCas9 | positive selection | 3102073 | 112286927 | 112286950 | 7 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.7593680599734391 | [3,3] | [3,4] | 9 | hSpCas9 | positive selection | 3102074 | 112327740 | 112327763 | | - | 24336571 | A375 | resistance to PLX after 7 days | AATGTTGAAAGCATGTTCTCTGG | ZNF277 | ENSG00000198839 | -0.19537275989495162 | [15,16] | [12,14] | -6 | hSpCas9 | positive selection | 3157260 | 112327769 | 112327792 | | - | 24336571 | A375 | resistance to PLX after 7 days | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | -0.05982392791477991 | [12,13] | [12,11] | -2 | hSpCas9 | positive selection | 3157261 | 112327740 | 112327763 | | - | 24336571 | A375 | resistance to PLX after 14 days | AATGTTGAAAGCATGTTCTCTGG | ZNF277 | ENSG00000198839 | -0.9368615524094508 | [17,13] | [3,2] | -9 | hSpCas9 | positive selection | 3215053 | 112327769 | 112327792 | | - | 24336571 | A375 | resistance to PLX after 14 days | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.1952971351595192 | [13,19] | [7,8] | 2 | hSpCas9 | positive selection | 3215054 | 112327740 | 112327763 | | - | 24336571 | A375 | viability after 7 days | AATGTTGAAAGCATGTTCTCTGG | ZNF277 | ENSG00000198839 | 0.35547370569830256 | [12] | [15,16] | 5 | hSpCas9 | negative selection | 3272846 | 112327769 | 112327792 | | - | 24336571 | A375 | viability after 7 days | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.2532030669379015 | [11] | [12,13] | 4 | hSpCas9 | negative selection | 3272847 | 112327740 | 112327763 | | - | 24336571 | A375 | viability after 14 days | AATGTTGAAAGCATGTTCTCTGG | ZNF277 | ENSG00000198839 | 0.3369417741731471 | [12] | [17,13] | 4 | hSpCas9 | negative selection | 3330639 | 112327769 | 112327792 | | - | 24336571 | A375 | viability after 14 days | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.5871565457151315 | [11] | [13,19] | 7 | hSpCas9 | negative selection | 3330640 | 112327742 | 112327765 | 7 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 4.7744356199845495 | [340,340] | [60,60] | 9 | hSpCas9 | positive selection | 3402724 | 112287036 | 112287059 | 7 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.8033697202417188 | [266,266] | [0,0] | -5 | hSpCas9 | positive selection | 3402725 | 112295951 | 112295974 | 7 | - | 26780180 | HT29 | viability (Avana library 4 designs) | CAAGATGTACACTTACCAAATGG | ZNF277 | ENSG00000198839 | -0.622781169685747 | [] | [] | -8 | hSpCas9 | negative selection | 3473533 | 112206719 | 112206742 | 7 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GGCTGCTTCCAAGACCCAGGGGG | ZNF277 | ENSG00000198839 | 1.32926449229125 | [] | [] | 5 | hSpCas9 | negative selection | 3473534 | 112286902 | 112286925 | 7 | + | 26780180 | HT29 | viability (Avana library 4 designs) | TCCCTGCCAGAAAGTCCAGGTGG | ZNF277 | ENSG00000198839 | 0.975171937523735 | [] | [] | 4 | hSpCas9 | negative selection | 3473535 | 112286927 | 112286950 | 7 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.283915021553659 | [] | [] | 1 | hSpCas9 | negative selection | 3473536 | 112286902 | 112286925 | 7 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TCCCTGCCAGAAAGTCCAGGTGG | ZNF277 | ENSG00000198839 | 3.32289215608713 | [] | [] | 5 | hSpCas9 | negative selection | 3581335 | 112206719 | 112206742 | 7 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGCTGCTTCCAAGACCCAGGGGG | ZNF277 | ENSG00000198839 | -0.370549492761847 | [] | [] | 0 | hSpCas9 | negative selection | 3581336 | 112286927 | 112286950 | 7 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.884719287343285 | [] | [] | 1 | hSpCas9 | negative selection | 3581337 | 112295951 | 112295974 | 7 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CAAGATGTACACTTACCAAATGG | ZNF277 | ENSG00000198839 | -3.57079696009214 | [] | [] | -4 | hSpCas9 | negative selection | 3581338 | 112287053 | 112287076 | 7 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AGTTGGTTGCTGATTTCCAAAGG | ZNF277 | ENSG00000198839 | -0.180509067078648 | [] | [] | 0 | hSpCas9 | negative selection | 3581339 | 112286896 | 112286919 | 7 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | 4.92517882295686 | [] | [] | 8 | hSpCas9 | negative selection | 3581340 | 112286902 | 112286925 | 7 | + | 26780180 | A375 | viability (Avana lentiGuide) | TCCCTGCCAGAAAGTCCAGGTGG | ZNF277 | ENSG00000198839 | -0.640605155754469 | [] | [] | -1 | hSpCas9 | negative selection | 3689994 | 112206719 | 112206742 | 7 | + | 26780180 | A375 | viability (Avana lentiGuide) | GGCTGCTTCCAAGACCCAGGGGG | ZNF277 | ENSG00000198839 | 13.8187357769699 | [] | [] | 7 | hSpCas9 | negative selection | 3689995 | 112286927 | 112286950 | 7 | - | 26780180 | A375 | viability (Avana lentiGuide) | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | -1.88204838424596 | [] | [] | -3 | hSpCas9 | negative selection | 3689996 | 112295951 | 112295974 | 7 | - | 26780180 | A375 | viability (Avana lentiGuide) | CAAGATGTACACTTACCAAATGG | ZNF277 | ENSG00000198839 | 4.7193256752065 | [] | [] | 4 | hSpCas9 | negative selection | 3689997 | 112287053 | 112287076 | 7 | + | 26780180 | A375 | viability (Avana lentiGuide) | AGTTGGTTGCTGATTTCCAAAGG | ZNF277 | ENSG00000198839 | 1.74884678304454 | [] | [] | 2 | hSpCas9 | negative selection | 3689998 | 112286896 | 112286919 | 7 | - | 26780180 | A375 | viability (Avana lentiGuide) | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | 0.716991327823563 | [] | [] | 0 | hSpCas9 | negative selection | 3689999 | 112286902 | 112286925 | 7 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TCCCTGCCAGAAAGTCCAGGTGG | ZNF277 | ENSG00000198839 | 0.08525939196959886 | [4] | [5,4] | 2 | hSpCas9 | positive selection | 3798601 | 112206719 | 112206742 | 7 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGCTGCTTCCAAGACCCAGGGGG | ZNF277 | ENSG00000198839 | -0.1059343570759459 | [3] | [3,3] | -2 | hSpCas9 | positive selection | 3798602 | 112286927 | 112286950 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | -0.012442097181666589 | [5] | [5,4] | 0 | hSpCas9 | positive selection | 3798603 | 112295951 | 112295974 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CAAGATGTACACTTACCAAATGG | ZNF277 | ENSG00000198839 | -0.19009769614339136 | [6] | [5,5] | -3 | hSpCas9 | positive selection | 3798604 | 112287053 | 112287076 | 7 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AGTTGGTTGCTGATTTCCAAAGG | ZNF277 | ENSG00000198839 | 0.16026929462485695 | [5] | [5,5] | 4 | hSpCas9 | positive selection | 3798605 | 112286896 | 112286919 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | 0.2896149362549419 | [4] | [5,5] | 8 | hSpCas9 | positive selection | 3798606 | 112286902 | 112286925 | 7 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TCCCTGCCAGAAAGTCCAGGTGG | ZNF277 | ENSG00000198839 | 0.14095677852179353 | [5] | [5,3] | 3 | hSpCas9 | positive selection | 3907208 | 112206719 | 112206742 | 7 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGCTGCTTCCAAGACCCAGGGGG | ZNF277 | ENSG00000198839 | -0.915660926500825 | [4] | [2,0] | -8 | hSpCas9 | positive selection | 3907209 | 112286927 | 112286950 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.18570246106917093 | [5] | [5,4] | 4 | hSpCas9 | positive selection | 3907210 | 112295951 | 112295974 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CAAGATGTACACTTACCAAATGG | ZNF277 | ENSG00000198839 | 0.169544219303074 | [6] | [5,5] | 4 | hSpCas9 | positive selection | 3907211 | 112287053 | 112287076 | 7 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AGTTGGTTGCTGATTTCCAAAGG | ZNF277 | ENSG00000198839 | 0.13032091787212918 | [5] | [5,5] | 3 | hSpCas9 | positive selection | 3907212 | 112286896 | 112286919 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | -0.5191681972933054 | [4] | [2,2] | -6 | hSpCas9 | positive selection | 3907213 | 112286871 | 112286894 | 7 | + | 26780180 | A375 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 2.30398818745256 | [] | [] | 9 | hSpCas9 | negative selection | 4015299 | 112327742 | 112327765 | 7 | + | 26780180 | A375 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.530469774927065 | [] | [] | 1 | hSpCas9 | negative selection | 4015300 | 112287036 | 112287059 | 7 | + | 26780180 | A375 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 1.31732224421606 | [] | [] | 7 | hSpCas9 | negative selection | 4015301 | 112327769 | 112327792 | 7 | - | 26780180 | A375 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 1.26339269941359 | [] | [] | 6 | hSpCas9 | negative selection | 4015302 | 112286871 | 112286894 | 7 | + | 26780180 | HT29 | viability (GeCKOv2 library) | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 1.68682100357135 | [] | [] | 8 | hSpCas9 | negative selection | 4123265 | 112327742 | 112327765 | 7 | + | 26780180 | HT29 | viability (GeCKOv2 library) | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.488214483169154 | [] | [] | 1 | hSpCas9 | negative selection | 4123266 | 112287036 | 112287059 | 7 | + | 26780180 | HT29 | viability (GeCKOv2 library) | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.49457760019179 | [] | [] | 1 | hSpCas9 | negative selection | 4123267 | 112327769 | 112327792 | 7 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 1.50256131771269 | [] | [] | 7 | hSpCas9 | negative selection | 4123268 | 112327740 | 112327763 | 7 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | AATGTTGAAAGCATGTTCTCTGG | ZNF277 | ENSG00000198839 | -0.11651580488207029 | [4] | [2,1] | -3 | hSpCas9 | positive selection | 4184300 | 112327769 | 112327792 | 7 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.235203941990883 | [3] | [2,3] | 6 | hSpCas9 | positive selection | 4184302 | 112327740 | 112327763 | 7 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | AATGTTGAAAGCATGTTCTCTGG | ZNF277 | ENSG00000198839 | 0.06867545036519834 | [3] | [1,0,4,0] | 0 | hSpCas9 | positive selection | 4248322 | 112327769 | 112327792 | 7 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.7290215691638992 | [3] | [5,3,2,0] | 5 | hSpCas9 | positive selection | 4248324 | 112327769 | 112327792 | 7 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | -0.537113119021293 | [2] | [1,0] | -8 | hSpCas9 | positive selection | 4309333 | 112286871 | 112286894 | 7 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 0.10347308780655484 | [3] | [3,2] | 2 | hSpCas9 | positive selection | 4309334 | 112327742 | 112327765 | 7 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.1122505604446779 | [3] | [3,2] | 2 | hSpCas9 | positive selection | 4373580 | 112287036 | 112287059 | 7 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.5473845924674813 | [3] | [3,4] | 9 | hSpCas9 | positive selection | 4373582 | 112286872 | 112286894 | 7 | + | 27760321 | OCIAML3 | viability | GACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 0.0792517097860681 | [122,117] | [87,114] | 0 | hSpCas9 | negative selection | 4456405 | 112286904 | 112286926 | 7 | - | 27760321 | OCIAML3 | viability | GCCACCTGGACTTTCTGGCAGG | ZNF277 | ENSG00000198839 | 0.6274023770862509 | [1517,1173] | [1544,1704] | 7 | hSpCas9 | negative selection | 4456406 | 112287037 | 112287059 | 7 | + | 27760321 | OCIAML3 | viability | GTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.1399885608910548 | [403,376] | [265,291] | -1 | hSpCas9 | negative selection | 4456407 | 112295906 | 112295928 | 7 | - | 27760321 | OCIAML3 | viability | CACTACAAAAATCTGTGATGGG | ZNF277 | ENSG00000198839 | 0.06695522731909587 | [146,97] | [95,102] | 0 | hSpCas9 | negative selection | 4456408 | 112295943 | 112295965 | 7 | - | 27760321 | OCIAML3 | viability | CACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.37520724362977276 | [515,485] | [492,528] | 4 | hSpCas9 | negative selection | 4456409 | 112286872 | 112286894 | 7 | + | 27760321 | OCIAML2 | viability | GACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -1.1736132368364904 | [122,117] | [22,69] | -8 | hSpCas9 | negative selection | 4539868 | 112286904 | 112286926 | 7 | - | 27760321 | OCIAML2 | viability | GCCACCTGGACTTTCTGGCAGG | ZNF277 | ENSG00000198839 | 0.5081119552621234 | [1517,1173] | [1331,1807] | 7 | hSpCas9 | negative selection | 4539869 | 112287037 | 112287059 | 7 | + | 27760321 | OCIAML2 | viability | GTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.03711971075910958 | [403,376] | [262,404] | 0 | hSpCas9 | negative selection | 4539870 | 112295906 | 112295928 | 7 | - | 27760321 | OCIAML2 | viability | CACTACAAAAATCTGTGATGGG | ZNF277 | ENSG00000198839 | -1.0855480031133302 | [146,97] | [33,61] | -7 | hSpCas9 | negative selection | 4539871 | 112295943 | 112295965 | 7 | - | 27760321 | OCIAML2 | viability | CACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.7511330794023074 | [515,485] | [557,846] | 8 | hSpCas9 | negative selection | 4539872 | 112286872 | 112286894 | 7 | + | 27760321 | MV411 | viability | GACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.9021355481634679 | [122,117] | [62,11] | -6 | hSpCas9 | negative selection | 4623331 | 112286904 | 112286926 | 7 | - | 27760321 | MV411 | viability | GCCACCTGGACTTTCTGGCAGG | ZNF277 | ENSG00000198839 | 0.7442455585861263 | [1517,1173] | [1652,1212] | 5 | hSpCas9 | negative selection | 4623332 | 112287037 | 112287059 | 7 | + | 27760321 | MV411 | viability | GTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.6878867019410192 | [403,376] | [203,93] | -5 | hSpCas9 | negative selection | 4623333 | 112295906 | 112295928 | 7 | - | 27760321 | MV411 | viability | CACTACAAAAATCTGTGATGGG | ZNF277 | ENSG00000198839 | 1.6804397148346788 | [146,97] | [379,68] | 9 | hSpCas9 | negative selection | 4623334 | 112295943 | 112295965 | 7 | - | 27760321 | MV411 | viability | CACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.7065781339954768 | [515,485] | [513,578] | 5 | hSpCas9 | negative selection | 4623335 | 112286872 | 112286894 | 7 | + | 27760321 | HL60 | viability | GACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.06941344013794293 | [122,117] | [75,112] | -1 | hSpCas9 | negative selection | 4706794 | 112286904 | 112286926 | 7 | - | 27760321 | HL60 | viability | GCCACCTGGACTTTCTGGCAGG | ZNF277 | ENSG00000198839 | 0.3982058808792093 | [1517,1173] | [1291,1593] | 5 | hSpCas9 | negative selection | 4706795 | 112287037 | 112287059 | 7 | + | 27760321 | HL60 | viability | GTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.3450040763711397 | [403,376] | [209,294] | -4 | hSpCas9 | negative selection | 4706796 | 112295906 | 112295928 | 7 | - | 27760321 | HL60 | viability | CACTACAAAAATCTGTGATGGG | ZNF277 | ENSG00000198839 | 1.0623547076633069 | [146,97] | [246,162] | 9 | hSpCas9 | negative selection | 4706797 | 112295943 | 112295965 | 7 | - | 27760321 | HL60 | viability | CACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 1.0864884848060097 | [515,485] | [829,911] | 9 | hSpCas9 | negative selection | 4706798 | 112286872 | 112286894 | 7 | + | 27760321 | HT1080 | viability | GACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 0.8237959052284919 | [117,91] | [0,153] | 4 | hSpCas9 | negative selection | 4790257 | 112286904 | 112286926 | 7 | - | 27760321 | HT1080 | viability | GCCACCTGGACTTTCTGGCAGG | ZNF277 | ENSG00000198839 | 1.0367596711934872 | [1173,915] | [728,990] | 5 | hSpCas9 | negative selection | 4790258 | 112287037 | 112287059 | 7 | + | 27760321 | HT1080 | viability | GTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 1.17956553062445 | [376,293] | [338,262] | 6 | hSpCas9 | negative selection | 4790259 | 112295906 | 112295928 | 7 | - | 27760321 | HT1080 | viability | CACTACAAAAATCTGTGATGGG | ZNF277 | ENSG00000198839 | 2.232792592929401 | [97,76] | [140,188] | 9 | hSpCas9 | negative selection | 4790260 | 112295943 | 112295965 | 7 | - | 27760321 | HT1080 | viability | CACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 2.1970287446016905 | [485,378] | [831,743] | 9 | hSpCas9 | negative selection | 4790261 | 112286872 | 112286894 | 7 | + | 27760321 | HT29 | viability after 7 days | GACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 0.2437998323616961 | [117,91] | [197,7,274] | 4 | hSpCas9 | negative selection | 4873720 | 112286904 | 112286926 | 7 | - | 27760321 | HT29 | viability after 7 days | GCCACCTGGACTTTCTGGCAGG | ZNF277 | ENSG00000198839 | 0.46110245691931273 | [1173,915] | [2461,1696,1485] | 7 | hSpCas9 | negative selection | 4873721 | 112287037 | 112287059 | 7 | + | 27760321 | HT29 | viability after 7 days | GTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.15565353402971654 | [376,293] | [526,392,264] | -2 | hSpCas9 | negative selection | 4873722 | 112295906 | 112295928 | 7 | - | 27760321 | HT29 | viability after 7 days | CACTACAAAAATCTGTGATGGG | ZNF277 | ENSG00000198839 | -0.06273344836506345 | [97,76] | [108,128,85] | -1 | hSpCas9 | negative selection | 4873723 | 112295943 | 112295965 | 7 | - | 27760321 | HT29 | viability after 7 days | CACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | -0.12018897410112012 | [485,378] | [421,578,519] | -2 | hSpCas9 | negative selection | 4873724 | 112286872 | 112286894 | 7 | + | 27760321 | HT29 | viability after 25 days | GACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.42736758112803197 | [117,91] | [52,82,138] | -4 | hSpCas9 | negative selection | 4957183 | 112286904 | 112286926 | 7 | - | 27760321 | HT29 | viability after 25 days | GCCACCTGGACTTTCTGGCAGG | ZNF277 | ENSG00000198839 | 0.9554078564691635 | [1173,915] | [1973,2031,3033] | 9 | hSpCas9 | negative selection | 4957184 | 112287037 | 112287059 | 7 | + | 27760321 | HT29 | viability after 25 days | GTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.5423273169717866 | [376,293] | [507,665,496] | 6 | hSpCas9 | negative selection | 4957185 | 112295906 | 112295928 | 7 | - | 27760321 | HT29 | viability after 25 days | CACTACAAAAATCTGTGATGGG | ZNF277 | ENSG00000198839 | 0.49288087772839284 | [97,76] | [72,103,261] | 5 | hSpCas9 | negative selection | 4957186 | 112295943 | 112295965 | 7 | - | 27760321 | HT29 | viability after 25 days | CACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.28157632046139613 | [485,378] | [612,574,613] | 3 | hSpCas9 | negative selection | 4957187 | 112286872 | 112286894 | 7 | + | 27760321 | HT29 | viability after 22 days | GACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.22029095163062928 | [117,91] | [124,82,103] | -2 | hSpCas9 | negative selection | 5040646 | 112286904 | 112286926 | 7 | - | 27760321 | HT29 | viability after 22 days | GCCACCTGGACTTTCTGGCAGG | ZNF277 | ENSG00000198839 | 0.8753993437152092 | [1173,915] | [2231,2308,2105] | 8 | hSpCas9 | negative selection | 5040647 | 112287037 | 112287059 | 7 | + | 27760321 | HT29 | viability after 22 days | GTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.21849351926803315 | [376,293] | [401,404,548] | 2 | hSpCas9 | negative selection | 5040648 | 112295906 | 112295928 | 7 | - | 27760321 | HT29 | viability after 22 days | CACTACAAAAATCTGTGATGGG | ZNF277 | ENSG00000198839 | 0.9155180359706472 | [97,76] | [127,185,260] | 9 | hSpCas9 | negative selection | 5040649 | 112295943 | 112295965 | 7 | - | 27760321 | HT29 | viability after 22 days | CACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.26742120680038295 | [485,378] | [772,499,526] | 2 | hSpCas9 | negative selection | 5040650 | 112286872 | 112286894 | 7 | + | 27760321 | HT29 | viability after 19 days | GACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.2070946213727336 | [117,91] | [105,203,5] | -2 | hSpCas9 | negative selection | 5124109 | 112286904 | 112286926 | 7 | - | 27760321 | HT29 | viability after 19 days | GCCACCTGGACTTTCTGGCAGG | ZNF277 | ENSG00000198839 | 0.9646999665416798 | [1173,915] | [2827,1734,2478] | 8 | hSpCas9 | negative selection | 5124110 | 112287037 | 112287059 | 7 | + | 27760321 | HT29 | viability after 19 days | GTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.8709626920962297 | [376,293] | [685,553,856] | 8 | hSpCas9 | negative selection | 5124111 | 112295906 | 112295928 | 7 | - | 27760321 | HT29 | viability after 19 days | CACTACAAAAATCTGTGATGGG | ZNF277 | ENSG00000198839 | 0.10722598572335995 | [97,76] | [105,75,139] | 1 | hSpCas9 | negative selection | 5124112 | 112295943 | 112295965 | 7 | - | 27760321 | HT29 | viability after 19 days | CACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.2830481404387104 | [485,378] | [711,405,694] | 2 | hSpCas9 | negative selection | 5124113 | 112286872 | 112286894 | 7 | + | 27760321 | HT29 | viability after 16 days | GACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 1.0418162000150377 | [117,91] | [301,56,376] | 9 | hSpCas9 | negative selection | 5207572 | 112286904 | 112286926 | 7 | - | 27760321 | HT29 | viability after 16 days | GCCACCTGGACTTTCTGGCAGG | ZNF277 | ENSG00000198839 | 1.1488311214086353 | [1173,915] | [2668,1975,3154] | 9 | hSpCas9 | negative selection | 5207573 | 112287037 | 112287059 | 7 | + | 27760321 | HT29 | viability after 16 days | GTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.2776666336340617 | [376,293] | [465,491,406] | 3 | hSpCas9 | negative selection | 5207574 | 112295906 | 112295928 | 7 | - | 27760321 | HT29 | viability after 16 days | CACTACAAAAATCTGTGATGGG | ZNF277 | ENSG00000198839 | 1.0477491955728118 | [97,76] | [262,281,65] | 9 | hSpCas9 | negative selection | 5207575 | 112295943 | 112295965 | 7 | - | 27760321 | HT29 | viability after 16 days | CACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.41164917634652565 | [485,378] | [703,585,647] | 4 | hSpCas9 | negative selection | 5207576 | 112286872 | 112286894 | 7 | + | 27760321 | HT29 | viability after 13 days | GACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 0.31656070109804957 | [117,91] | [187,81,182] | 4 | hSpCas9 | negative selection | 5291035 | 112286904 | 112286926 | 7 | - | 27760321 | HT29 | viability after 13 days | GCCACCTGGACTTTCTGGCAGG | ZNF277 | ENSG00000198839 | 0.5931611897306543 | [1173,915] | [1782,1956,1750] | 7 | hSpCas9 | negative selection | 5291036 | 112287037 | 112287059 | 7 | + | 27760321 | HT29 | viability after 13 days | GTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.14395139192519246 | [376,293] | [404,572,318] | 1 | hSpCas9 | negative selection | 5291037 | 112295906 | 112295928 | 7 | - | 27760321 | HT29 | viability after 13 days | CACTACAAAAATCTGTGATGGG | ZNF277 | ENSG00000198839 | 0.6391544947450014 | [97,76] | [266,113,96] | 8 | hSpCas9 | negative selection | 5291038 | 112295943 | 112295965 | 7 | - | 27760321 | HT29 | viability after 13 days | CACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.3064635169199845 | [485,378] | [722,516,620] | 4 | hSpCas9 | negative selection | 5291039 | 112286872 | 112286894 | 7 | + | 27760321 | HT29 | viability after 10 days | GACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.5648243532886299 | [117,91] | [89,90,84] | -6 | hSpCas9 | negative selection | 5374498 | 112286904 | 112286926 | 7 | - | 27760321 | HT29 | viability after 10 days | GCCACCTGGACTTTCTGGCAGG | ZNF277 | ENSG00000198839 | 0.48463771530146293 | [1173,915] | [2134,1716,1625] | 6 | hSpCas9 | negative selection | 5374499 | 112287037 | 112287059 | 7 | + | 27760321 | HT29 | viability after 10 days | GTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.08812147637831826 | [376,293] | [287,539,358] | -1 | hSpCas9 | negative selection | 5374500 | 112295906 | 112295928 | 7 | - | 27760321 | HT29 | viability after 10 days | CACTACAAAAATCTGTGATGGG | ZNF277 | ENSG00000198839 | 1.0857566836006591 | [97,76] | [294,185,213] | 9 | hSpCas9 | negative selection | 5374501 | 112295943 | 112295965 | 7 | - | 27760321 | HT29 | viability after 10 days | CACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.025653523980888437 | [485,378] | [490,537,617] | 0 | hSpCas9 | negative selection | 5374502 | 112286872 | 112286894 | 7 | + | 27760321 | MOLM13 | viability | GACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 0.37771419222766855 | [122,117] | [182,7] | 2 | hSpCas9 | negative selection | 5457961 | 112286904 | 112286926 | 7 | - | 27760321 | MOLM13 | viability | GCCACCTGGACTTTCTGGCAGG | ZNF277 | ENSG00000198839 | 1.6244104307758322 | [1517,1173] | [3534,1293] | 9 | hSpCas9 | negative selection | 5457962 | 112287037 | 112287059 | 7 | + | 27760321 | MOLM13 | viability | GTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 1.9339369617088271 | [403,376] | [92,1479] | 9 | hSpCas9 | negative selection | 5457963 | 112295906 | 112295928 | 7 | - | 27760321 | MOLM13 | viability | CACTACAAAAATCTGTGATGGG | ZNF277 | ENSG00000198839 | 1.0772099415828285 | [146,97] | [171,119] | 7 | hSpCas9 | negative selection | 5457964 | 112295943 | 112295965 | 7 | - | 27760321 | MOLM13 | viability | CACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.8377479373215457 | [515,485] | [483,523] | 6 | hSpCas9 | negative selection | 5457965 | 112206771 | 112206794 | 7 | + | 27661255 | K562 | viability | GGGAGCTGCAGCACAGTCGGGGG | ZNF277 | ENSG00000198839 | 0.123491236690208 | [666,845] | [675,637] | 4 | dCas9-KRAB | negative selection | 5524541 | 112206727 | 112206750 | 7 | - | 27661255 | K562 | viability | GGCGACAGCCCCCTGGGTCTTGG | ZNF277 | ENSG00000198839 | 0.07665241516739618 | [220,186] | [180,164] | 2 | dCas9-KRAB | negative selection | 5524542 | 112206875 | 112206898 | 7 | - | 27661255 | K562 | viability | GGCTCCTAGGGTCAGACCAGAGG | ZNF277 | ENSG00000198839 | -0.0027151602050812795 | [863,847] | [787,592] | 0 | dCas9-KRAB | negative selection | 5524543 | 112327769 | 112327792 | 7 | - | 27260156 | BXPC3 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | -0.02815709384665066 | [309] | [211,343,380,346] | 0 | hSpCas9 | negative selection | 5581793 | 112286871 | 112286894 | 7 | + | 27260156 | BXPC3 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.11411520332744662 | [837] | [699,825,779,954] | -3 | hSpCas9 | negative selection | 5581794 | 112327742 | 112327765 | 7 | + | 27260156 | BXPC3 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.08471407275630138 | [858] | [728,893,1010,1232] | 1 | hSpCas9 | negative selection | 5646040 | 112287036 | 112287059 | 7 | + | 27260156 | BXPC3 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.09044827790166166 | [663] | [632,635,934,772] | 2 | hSpCas9 | negative selection | 5646042 | 112327769 | 112327792 | 7 | - | 27260156 | A673 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.20554312881631248 | [309] | [512,468,382,355] | 5 | hSpCas9 | negative selection | 5703044 | 112286871 | 112286894 | 7 | + | 27260156 | A673 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.16529290005497543 | [837] | [1054,834,774,945] | -4 | hSpCas9 | negative selection | 5703045 | 112327742 | 112327765 | 7 | + | 27260156 | A673 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.037512039357533555 | [858] | [1092,1091,1020,1027] | 0 | hSpCas9 | negative selection | 5767291 | 112287036 | 112287059 | 7 | + | 27260156 | A673 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.023906433839417596 | [663] | [904,671,878,797] | 0 | hSpCas9 | negative selection | 5767293 | 112327769 | 112327792 | 7 | - | 27260156 | A375 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.2563049436135523 | [309] | [418,344,593,365] | 4 | hSpCas9 | negative selection | 5824295 | 112286871 | 112286894 | 7 | + | 27260156 | A375 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.11325835710224341 | [837] | [1227,968,864,601] | -2 | hSpCas9 | negative selection | 5824296 | 112327742 | 112327765 | 7 | + | 27260156 | A375 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | -0.13552274816689647 | [858] | [913,1183,1022,603] | -2 | hSpCas9 | negative selection | 5888542 | 112287036 | 112287059 | 7 | + | 27260156 | A375 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.07925241548343775 | [663] | [790,743,718,686] | -1 | hSpCas9 | negative selection | 5888544 | 112327769 | 112327792 | 7 | - | 27260156 | COLO741 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | -0.1353441623402062 | [309] | [468,301,321] | -3 | hSpCas9 | negative selection | 5945546 | 112286871 | 112286894 | 7 | + | 27260156 | COLO741 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.16151492821510782 | [837] | [984,858,1022] | -3 | hSpCas9 | negative selection | 5945547 | 112327742 | 112327765 | 7 | + | 27260156 | COLO741 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.04126884818902121 | [858] | [1164,1043,1175] | 0 | hSpCas9 | negative selection | 6009793 | 112287036 | 112287059 | 7 | + | 27260156 | COLO741 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.07176844789805614 | [663] | [980,795,667] | -1 | hSpCas9 | negative selection | 6009795 | 112327769 | 112327792 | 7 | - | 27260156 | CAL120 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.0004680203407401162 | [309] | [548,300,332] | 0 | hSpCas9 | negative selection | 6066797 | 112286871 | 112286894 | 7 | + | 27260156 | CAL120 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.09567701940521156 | [837] | [1249,938,782] | -1 | hSpCas9 | negative selection | 6066798 | 112327742 | 112327765 | 7 | + | 27260156 | CAL120 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.2056781657377975 | [858] | [1449,972,1305] | 3 | hSpCas9 | negative selection | 6131044 | 112287036 | 112287059 | 7 | + | 27260156 | CAL120 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.006144508298186413 | [663] | [896,808,773] | 0 | hSpCas9 | negative selection | 6131046 | 112327769 | 112327792 | 7 | - | 27260156 | CADOES1 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.3874637985946736 | [309] | [341,499,313,351] | 6 | hSpCas9 | negative selection | 6188048 | 112286871 | 112286894 | 7 | + | 27260156 | CADOES1 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.22388610905560735 | [837] | [785,614,524,745] | -4 | hSpCas9 | negative selection | 6188049 | 112327742 | 112327765 | 7 | + | 27260156 | CADOES1 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.06599247949724929 | [858] | [654,758,903,1034] | 1 | hSpCas9 | negative selection | 6252295 | 112287036 | 112287059 | 7 | + | 27260156 | CADOES1 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.0688361303738586 | [663] | [716,749,527,593] | 1 | hSpCas9 | negative selection | 6252297 | 112327769 | 112327792 | 7 | - | 27260156 | EWS502 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.2504556384128531 | [309] | [484,251,404,414] | 4 | hSpCas9 | negative selection | 6309299 | 112286871 | 112286894 | 7 | + | 27260156 | EWS502 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 0.08227058044215263 | [837] | [1074,825,897,943] | 1 | hSpCas9 | negative selection | 6309300 | 112327742 | 112327765 | 7 | + | 27260156 | EWS502 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.09754197483353022 | [858] | [931,859,799,1330] | 1 | hSpCas9 | negative selection | 6373546 | 112287036 | 112287059 | 7 | + | 27260156 | EWS502 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.048795914366320414 | [663] | [525,712,627,880] | -1 | hSpCas9 | negative selection | 6373548 | 112327769 | 112327792 | 7 | - | 27260156 | EW8 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.11624404904820423 | [309] | [328,199,219,353] | 2 | hSpCas9 | negative selection | 6430550 | 112286871 | 112286894 | 7 | + | 27260156 | EW8 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.08477795816198497 | [837] | [743,721,501,626] | -1 | hSpCas9 | negative selection | 6430551 | 112327742 | 112327765 | 7 | + | 27260156 | EW8 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.20660901233987206 | [858] | [1189,561,567,971] | 4 | hSpCas9 | negative selection | 6494797 | 112287036 | 112287059 | 7 | + | 27260156 | EW8 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.24722703257879797 | [663] | [627,808,392,763] | 4 | hSpCas9 | negative selection | 6494799 | 112327769 | 112327792 | 7 | - | 27260156 | CORL105 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.4612638917358881 | [309] | [411,448,675,486] | 8 | hSpCas9 | negative selection | 6551801 | 112286871 | 112286894 | 7 | + | 27260156 | CORL105 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.053643401590965256 | [837] | [921,646,1055,1176] | -1 | hSpCas9 | negative selection | 6551802 | 112327742 | 112327765 | 7 | + | 27260156 | CORL105 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | -0.04839749000209326 | [858] | [1108,1033,917,823] | -1 | hSpCas9 | negative selection | 6616048 | 112287036 | 112287059 | 7 | + | 27260156 | CORL105 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.13591668568743653 | [663] | [484,834,794,717] | -3 | hSpCas9 | negative selection | 6616050 | 112327769 | 112327792 | 7 | - | 27260156 | HS294T | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 1.173558051880922 | [309] | [301,412,194,140] | 9 | hSpCas9 | negative selection | 6673052 | 112286871 | 112286894 | 7 | + | 27260156 | HS294T | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.6737317752904141 | [837] | [169,178,247,221] | -7 | hSpCas9 | negative selection | 6673053 | 112327742 | 112327765 | 7 | + | 27260156 | HS294T | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.03971027717166409 | [858] | [404,312,315,321] | 0 | hSpCas9 | negative selection | 6737299 | 112287036 | 112287059 | 7 | + | 27260156 | HS294T | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.006537931549862042 | [663] | [195,222,265,371] | 0 | hSpCas9 | negative selection | 6737301 | 112327769 | 112327792 | 7 | - | 27260156 | HCC44 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.3311946751637264 | [309] | [465,342,700,315] | 5 | hSpCas9 | negative selection | 6794303 | 112286871 | 112286894 | 7 | + | 27260156 | HCC44 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 0.2600727589202433 | [837] | [1071,1019,1182,1269] | 4 | hSpCas9 | negative selection | 6794304 | 112327742 | 112327765 | 7 | + | 27260156 | HCC44 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.0827365956178634 | [858] | [921,795,1590,921] | 1 | hSpCas9 | negative selection | 6858550 | 112287036 | 112287059 | 7 | + | 27260156 | HCC44 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.12325642783189822 | [663] | [649,747,621,707] | -2 | hSpCas9 | negative selection | 6858552 | 112327769 | 112327792 | 7 | - | 27260156 | G402 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.48196602597614774 | [309] | [757,352,576,449] | 6 | hSpCas9 | negative selection | 6915554 | 112286871 | 112286894 | 7 | + | 27260156 | G402 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.3362897511238854 | [837] | [1014,762,708,777] | -4 | hSpCas9 | negative selection | 6915555 | 112327742 | 112327765 | 7 | + | 27260156 | G402 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.1067264740024173 | [858] | [972,978,1398,1127] | 1 | hSpCas9 | negative selection | 6979801 | 112287036 | 112287059 | 7 | + | 27260156 | G402 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.019618578189014246 | [663] | [904,949,654,792] | 0 | hSpCas9 | negative selection | 6979803 | 112327769 | 112327792 | 7 | - | 27260156 | L33 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | -0.18462514761706517 | [309] | [330,94,182,235] | -4 | hSpCas9 | negative selection | 7036805 | 112286871 | 112286894 | 7 | + | 27260156 | L33 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.1266593566073846 | [837] | [778,339,458,730] | -3 | hSpCas9 | negative selection | 7036806 | 112327742 | 112327765 | 7 | + | 27260156 | L33 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | -0.16494411690923716 | [858] | [674,324,478,835] | -4 | hSpCas9 | negative selection | 7101052 | 112287036 | 112287059 | 7 | + | 27260156 | L33 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.013359639259722333 | [663] | [669,283,381,659] | 0 | hSpCas9 | negative selection | 7101054 | 112327769 | 112327792 | 7 | - | 27260156 | K562 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.7987398619427711 | [309] | [361,912,157,490] | 8 | hSpCas9 | negative selection | 7158056 | 112286871 | 112286894 | 7 | + | 27260156 | K562 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.03536743557110911 | [837] | [1078,646,780,449] | 0 | hSpCas9 | negative selection | 7158057 | 112327742 | 112327765 | 7 | + | 27260156 | K562 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | -0.3072801858520985 | [858] | [667,732,435,632] | -4 | hSpCas9 | negative selection | 7222303 | 112287036 | 112287059 | 7 | + | 27260156 | K562 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.09003496425368657 | [663] | [798,532,693,241] | -1 | hSpCas9 | negative selection | 7222305 | 112327769 | 112327792 | 7 | - | 27260156 | HT29 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.11626934286036728 | [309] | [518,334,360,416] | 2 | hSpCas9 | negative selection | 7279307 | 112286871 | 112286894 | 7 | + | 27260156 | HT29 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.08922637313253856 | [837] | [1078,937,972,853] | -2 | hSpCas9 | negative selection | 7279308 | 112327742 | 112327765 | 7 | + | 27260156 | HT29 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.033174579185125896 | [858] | [1139,1204,982,967] | 0 | hSpCas9 | negative selection | 7343554 | 112287036 | 112287059 | 7 | + | 27260156 | HT29 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.11102136492948267 | [663] | [911,851,1007,727] | 2 | hSpCas9 | negative selection | 7343556 | 112327769 | 112327792 | 7 | - | 27260156 | MHHES1 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.3765623086776767 | [309] | [630,429,550,256] | 6 | hSpCas9 | negative selection | 7400558 | 112286871 | 112286894 | 7 | + | 27260156 | MHHES1 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.15306674652813723 | [837] | [1419,693,755,613] | -3 | hSpCas9 | negative selection | 7400559 | 112327742 | 112327765 | 7 | + | 27260156 | MHHES1 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.018557068240682817 | [858] | [934,1247,1015,769] | 0 | hSpCas9 | negative selection | 7464805 | 112287036 | 112287059 | 7 | + | 27260156 | MHHES1 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.014717901559274715 | [663] | [931,816,655,601] | 0 | hSpCas9 | negative selection | 7464807 | 112327769 | 112327792 | 7 | - | 27260156 | MEWO | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.08821550674175016 | [309] | [379,257,300] | 2 | hSpCas9 | negative selection | 7521809 | 112286871 | 112286894 | 7 | + | 27260156 | MEWO | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.35885592081596496 | [837] | [705,662,482] | -7 | hSpCas9 | negative selection | 7521810 | 112327742 | 112327765 | 7 | + | 27260156 | MEWO | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.03804592835677534 | [858] | [969,876,655] | 0 | hSpCas9 | negative selection | 7586056 | 112287036 | 112287059 | 7 | + | 27260156 | MEWO | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.044077925405985374 | [663] | [747,522,564] | -1 | hSpCas9 | negative selection | 7586058 | 112327769 | 112327792 | 7 | - | 27260156 | LNCAPCLONEFGC | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.4021456142316681 | [309] | [367,284,398,441] | 6 | hSpCas9 | negative selection | 7643060 | 112286871 | 112286894 | 7 | + | 27260156 | LNCAPCLONEFGC | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.13879077883612045 | [837] | [826,650,720,562] | -2 | hSpCas9 | negative selection | 7643061 | 112327742 | 112327765 | 7 | + | 27260156 | LNCAPCLONEFGC | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | -0.12657931489396856 | [858] | [746,466,933,750] | -2 | hSpCas9 | negative selection | 7707307 | 112287036 | 112287059 | 7 | + | 27260156 | LNCAPCLONEFGC | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.06190763037216035 | [663] | [486,695,654,471] | -1 | hSpCas9 | negative selection | 7707309 | 112327769 | 112327792 | 7 | - | 27260156 | PANC0327 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | -0.06245549087733171 | [309] | [151,444,153,270] | -1 | hSpCas9 | negative selection | 7764311 | 112286871 | 112286894 | 7 | + | 27260156 | PANC0327 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.10587296714957062 | [837] | [614,810,663,654] | -1 | hSpCas9 | negative selection | 7764312 | 112327742 | 112327765 | 7 | + | 27260156 | PANC0327 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | -0.24950277377331043 | [858] | [804,877,443,422] | -4 | hSpCas9 | negative selection | 7828558 | 112287036 | 112287059 | 7 | + | 27260156 | PANC0327 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.3845900169270795 | [663] | [780,1000,714,553] | 6 | hSpCas9 | negative selection | 7828560 | 112327769 | 112327792 | 7 | - | 27260156 | NCIH2009 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.3704070956843196 | [309] | [623,582,483] | 5 | hSpCas9 | negative selection | 7885562 | 112286871 | 112286894 | 7 | + | 27260156 | NCIH2009 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.23729009621353214 | [837] | [1184,990,839] | -3 | hSpCas9 | negative selection | 7885563 | 112327742 | 112327765 | 7 | + | 27260156 | NCIH2009 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.06576636794597257 | [858] | [1115,956,1670] | 0 | hSpCas9 | negative selection | 7949809 | 112287036 | 112287059 | 7 | + | 27260156 | NCIH2009 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.10058102236421285 | [663] | [1187,591,882] | -1 | hSpCas9 | negative selection | 7949811 | 112327769 | 112327792 | 7 | - | 27260156 | NCIH1373 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.7855890921017604 | [309] | [827,614,526,117] | 7 | hSpCas9 | negative selection | 8006813 | 112286871 | 112286894 | 7 | + | 27260156 | NCIH1373 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.5045546692282683 | [837] | [888,256,679,239] | -5 | hSpCas9 | negative selection | 8006814 | 112327742 | 112327765 | 7 | + | 27260156 | NCIH1373 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | -0.3631785290506533 | [858] | [1148,483,440,270] | -4 | hSpCas9 | negative selection | 8071060 | 112287036 | 112287059 | 7 | + | 27260156 | NCIH1373 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.5584912638666701 | [663] | [504,523,453,140] | -5 | hSpCas9 | negative selection | 8071062 | 112327769 | 112327792 | 7 | - | 27260156 | PATU8902 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.7356288917325717 | [309] | [901,975,445,600] | 7 | hSpCas9 | negative selection | 8128064 | 112286871 | 112286894 | 7 | + | 27260156 | PATU8902 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 0.0845159956457997 | [837] | [978,1630,890,1573] | 0 | hSpCas9 | negative selection | 8128065 | 112327742 | 112327765 | 7 | + | 27260156 | PATU8902 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | -0.06018609005021225 | [858] | [1578,1295,693,1120] | 0 | hSpCas9 | negative selection | 8192311 | 112287036 | 112287059 | 7 | + | 27260156 | PATU8902 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.4345533537824763 | [663] | [765,1243,1526,1404] | 4 | hSpCas9 | negative selection | 8192313 | 112327769 | 112327792 | 7 | - | 27260156 | PANC1 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.05805416920277351 | [309] | [290,300,249,267] | 0 | hSpCas9 | negative selection | 8249315 | 112286871 | 112286894 | 7 | + | 27260156 | PANC1 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.04522797232091125 | [837] | [593,886,632,703] | 0 | hSpCas9 | negative selection | 8249316 | 112327742 | 112327765 | 7 | + | 27260156 | PANC1 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.10439457525212259 | [858] | [705,996,835,682] | 1 | hSpCas9 | negative selection | 8313562 | 112287036 | 112287059 | 7 | + | 27260156 | PANC1 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.17322029009552686 | [663] | [640,641,666,615] | 2 | hSpCas9 | negative selection | 8313564 | 112327769 | 112327792 | 7 | - | 27260156 | PANC0813 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.5362554608603702 | [309] | [526,602,522,461] | 8 | hSpCas9 | negative selection | 8370566 | 112286871 | 112286894 | 7 | + | 27260156 | PANC0813 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.1498868696151474 | [837] | [1025,828,904,804] | -2 | hSpCas9 | negative selection | 8370567 | 112327742 | 112327765 | 7 | + | 27260156 | PANC0813 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | -0.0008268644984038565 | [858] | [1207,1006,1123,727] | 0 | hSpCas9 | negative selection | 8434813 | 112287036 | 112287059 | 7 | + | 27260156 | PANC0813 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.2425993958683259 | [663] | [619,641,839,537] | -4 | hSpCas9 | negative selection | 8434815 | 112327769 | 112327792 | 7 | - | 27260156 | RDES | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.3880777739463483 | [309] | [319,395,569,635] | 6 | hSpCas9 | negative selection | 8491817 | 112286871 | 112286894 | 7 | + | 27260156 | RDES | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 0.0016419240997954665 | [837] | [725,1011,1056,1107] | 0 | hSpCas9 | negative selection | 8491818 | 112327742 | 112327765 | 7 | + | 27260156 | RDES | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.09049987680263905 | [858] | [994,1047,1023,1127] | 1 | hSpCas9 | negative selection | 8556064 | 112287036 | 112287059 | 7 | + | 27260156 | RDES | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.03928040837967367 | [663] | [664,627,872,828] | 0 | hSpCas9 | negative selection | 8556066 | 112327769 | 112327792 | 7 | - | 27260156 | PC3 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | -0.16102543161598348 | [309] | [210,278,479,207] | -4 | hSpCas9 | negative selection | 8613068 | 112286871 | 112286894 | 7 | + | 27260156 | PC3 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.0660194843092089 | [837] | [478,690,1591,811] | -1 | hSpCas9 | negative selection | 8613069 | 112327742 | 112327765 | 7 | + | 27260156 | PC3 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.01406323626396988 | [858] | [620,785,1614,739] | 0 | hSpCas9 | negative selection | 8677315 | 112287036 | 112287059 | 7 | + | 27260156 | PC3 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.03334695059300907 | [663] | [544,740,1012,503] | 0 | hSpCas9 | negative selection | 8677317 | 112327769 | 112327792 | 7 | - | 27260156 | PATU8988T | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | -0.37062164507464757 | [309] | [182,307,202,240] | -6 | hSpCas9 | negative selection | 8734319 | 112286871 | 112286894 | 7 | + | 27260156 | PATU8988T | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.09300332657742472 | [837] | [683,755,672,938] | -2 | hSpCas9 | negative selection | 8734320 | 112327742 | 112327765 | 7 | + | 27260156 | PATU8988T | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.10599976250819754 | [858] | [855,885,954,872] | 1 | hSpCas9 | negative selection | 8798566 | 112287036 | 112287059 | 7 | + | 27260156 | PATU8988T | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.11812295843860637 | [663] | [523,434,553,858] | -2 | hSpCas9 | negative selection | 8798568 | 112327769 | 112327792 | 7 | - | 27260156 | T47D | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.2939008697578954 | [309] | [520,366,379,512] | 6 | hSpCas9 | negative selection | 8855570 | 112286871 | 112286894 | 7 | + | 27260156 | T47D | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.024163724960038935 | [837] | [963,890,943,1049] | 0 | hSpCas9 | negative selection | 8855571 | 112327742 | 112327765 | 7 | + | 27260156 | T47D | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.026048546542137285 | [858] | [1021,960,1089,1005] | 0 | hSpCas9 | negative selection | 8919817 | 112287036 | 112287059 | 7 | + | 27260156 | T47D | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.1348591096783064 | [663] | [830,804,870,894] | 3 | hSpCas9 | negative selection | 8919819 | 112327769 | 112327792 | 7 | - | 27260156 | SU8686 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.3188260050511379 | [309] | [243,471,364,466] | 5 | hSpCas9 | negative selection | 8976821 | 112286871 | 112286894 | 7 | + | 27260156 | SU8686 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.012245163412690774 | [837] | [809,772,780,952] | 0 | hSpCas9 | negative selection | 8976822 | 112327742 | 112327765 | 7 | + | 27260156 | SU8686 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.014027620794101914 | [858] | [808,683,906,1102] | 0 | hSpCas9 | negative selection | 9041068 | 112287036 | 112287059 | 7 | + | 27260156 | SU8686 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.08317697835764282 | [663] | [595,501,909,842] | 1 | hSpCas9 | negative selection | 9041070 | 112327769 | 112327792 | 7 | - | 27260156 | SKES1 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | -0.007987567266186213 | [309] | [253,295,314,347] | 0 | hSpCas9 | negative selection | 9098072 | 112286871 | 112286894 | 7 | + | 27260156 | SKES1 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | 0.004608468722878567 | [837] | [897,1024,792,679] | 0 | hSpCas9 | negative selection | 9098073 | 112327742 | 112327765 | 7 | + | 27260156 | SKES1 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.048267774917941875 | [858] | [1149,962,807,684] | 1 | hSpCas9 | negative selection | 9162319 | 112287036 | 112287059 | 7 | + | 27260156 | SKES1 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.18581484346346105 | [663] | [603,670,458,601] | -4 | hSpCas9 | negative selection | 9162321 | 112327769 | 112327792 | 7 | - | 27260156 | TOV112D | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.0525599506798744 | [309] | [268,473,312,265] | 1 | hSpCas9 | negative selection | 9219323 | 112286871 | 112286894 | 7 | + | 27260156 | TOV112D | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.12484465541016676 | [837] | [747,1204,680,554] | -2 | hSpCas9 | negative selection | 9219324 | 112327742 | 112327765 | 7 | + | 27260156 | TOV112D | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | -0.07689365042971608 | [858] | [702,966,871,748] | -1 | hSpCas9 | negative selection | 9283570 | 112287036 | 112287059 | 7 | + | 27260156 | TOV112D | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.18955974338196213 | [663] | [540,859,876,760] | 3 | hSpCas9 | negative selection | 9283572 | 112327769 | 112327792 | 7 | - | 27260156 | TC71 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | -0.05058552365426361 | [309] | [227,397,326,332] | -1 | hSpCas9 | negative selection | 9340574 | 112286871 | 112286894 | 7 | + | 27260156 | TC71 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.16372753476040036 | [837] | [749,916,738,804] | -4 | hSpCas9 | negative selection | 9340575 | 112327742 | 112327765 | 7 | + | 27260156 | TC71 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.014857839489696767 | [858] | [990,919,944,858] | 0 | hSpCas9 | negative selection | 9404821 | 112287036 | 112287059 | 7 | + | 27260156 | TC71 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | 0.10909935169221796 | [663] | [812,809,586,871] | 2 | hSpCas9 | negative selection | 9404823 | 112327769 | 112327792 | 7 | - | 27260156 | TC32 | viability | TTGCAGTTTACAATGTTGTCTGG | ZNF277 | ENSG00000198839 | 0.12035453063307516 | [309] | [304,250,431,304] | 2 | hSpCas9 | negative selection | 9461825 | 112286871 | 112286894 | 7 | + | 27260156 | TC32 | viability | AGACAGTAAGGATTGTATCCTGG | ZNF277 | ENSG00000198839 | -0.10511056000108066 | [837] | [542,625,916,904] | -2 | hSpCas9 | negative selection | 9461826 | 112327742 | 112327765 | 7 | + | 27260156 | TC32 | viability | AGAGAACATGCTTTCAACATTGG | ZNF277 | ENSG00000198839 | 0.15082878351352802 | [858] | [966,732,1009,889] | 2 | hSpCas9 | negative selection | 9526072 | 112287036 | 112287059 | 7 | + | 27260156 | TC32 | viability | TGTCATAGCTGATGTCAAGTTGG | ZNF277 | ENSG00000198839 | -0.1850916854102903 | [663] | [483,322,763,735] | -3 | hSpCas9 | negative selection | 9526074 | 112295943 | 112295966 | 7 | - | 28162770 | P31FUJ | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | -1.2328022044143785 | [77] | [38] | -7 | hSpCas9 | negative selection | 10269760 | 112286947 | 112286970 | 7 | - | 28162770 | P31FUJ | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | -1.0093639729263797 | [196] | [114] | -6 | hSpCas9 | negative selection | 10269761 | 112206717 | 112206740 | 7 | + | 28162770 | P31FUJ | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | -0.4005296501524451 | [245] | [218] | -4 | hSpCas9 | negative selection | 10269762 | 112206770 | 112206793 | 7 | + | 28162770 | P31FUJ | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | -0.11732498699444271 | [131] | [142] | -1 | hSpCas9 | negative selection | 10269763 | 112206750 | 112206773 | 7 | + | 28162770 | P31FUJ | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | -0.26109124884580215 | [514] | [504] | -2 | hSpCas9 | negative selection | 10269764 | 112286927 | 112286950 | 7 | - | 28162770 | P31FUJ | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | -0.6343941726282707 | [711] | [538] | -5 | hSpCas9 | negative selection | 10269765 | 112296290 | 112296313 | 7 | + | 28162770 | P31FUJ | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 0.6329694038685474 | [241] | [440] | 7 | hSpCas9 | negative selection | 10269766 | 112286896 | 112286919 | 7 | - | 28162770 | P31FUJ | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | -0.4331553774920377 | [562] | [489] | -4 | hSpCas9 | negative selection | 10269767 | 112295943 | 112295966 | 7 | - | 28162770 | TF1 | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | NaN | [NaN] | [15] | 1 | hSpCas9 | negative selection | 10439126 | 112286947 | 112286970 | 7 | - | 28162770 | TF1 | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | NaN | [NaN] | [99] | 1 | hSpCas9 | negative selection | 10439127 | 112206717 | 112206740 | 7 | + | 28162770 | TF1 | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | NaN | [NaN] | [202] | 1 | hSpCas9 | negative selection | 10439128 | 112206770 | 112206793 | 7 | + | 28162770 | TF1 | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | NaN | [NaN] | [169] | 1 | hSpCas9 | negative selection | 10439129 | 112206750 | 112206773 | 7 | + | 28162770 | TF1 | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | NaN | [NaN] | [522] | 1 | hSpCas9 | negative selection | 10439130 | 112286927 | 112286950 | 7 | - | 28162770 | TF1 | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | NaN | [NaN] | [628] | 1 | hSpCas9 | negative selection | 10439131 | 112296290 | 112296313 | 7 | + | 28162770 | TF1 | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | NaN | [NaN] | [319] | 1 | hSpCas9 | negative selection | 10439132 | 112286896 | 112286919 | 7 | - | 28162770 | TF1 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | NaN | [NaN] | [340] | 1 | hSpCas9 | negative selection | 10439133 | 112295943 | 112295966 | 7 | - | 28162770 | SKM1 | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | -0.5000736031346431 | [15] | [19] | -4 | hSpCas9 | negative selection | 10608492 | 112286947 | 112286970 | 7 | - | 28162770 | SKM1 | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | 0.5259216053983014 | [32] | [83] | 5 | hSpCas9 | negative selection | 10608493 | 112206717 | 112206740 | 7 | + | 28162770 | SKM1 | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | 0.11176460357790763 | [77] | [148] | 1 | hSpCas9 | negative selection | 10608494 | 112206770 | 112206793 | 7 | + | 28162770 | SKM1 | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | 1.043068721891886 | [27] | [101] | 8 | hSpCas9 | negative selection | 10608495 | 112206750 | 112206773 | 7 | + | 28162770 | SKM1 | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | 0.5374584533619582 | [128] | [330] | 5 | hSpCas9 | negative selection | 10608496 | 112286927 | 112286950 | 7 | - | 28162770 | SKM1 | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.4536327445914221 | [170] | [413] | 4 | hSpCas9 | negative selection | 10608497 | 112296290 | 112296313 | 7 | + | 28162770 | SKM1 | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 0.11386796455827874 | [68] | [131] | 1 | hSpCas9 | negative selection | 10608498 | 112286896 | 112286919 | 7 | - | 28162770 | SKM1 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | -0.28878277239484773 | [122] | [177] | -2 | hSpCas9 | negative selection | 10608499 | 112295943 | 112295966 | 7 | - | 28162770 | SKM1 | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | -0.5000736031346431 | [15] | [19] | -4 | hSpCas9 | negative selection | 10777858 | 112286947 | 112286970 | 7 | - | 28162770 | SKM1 | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | 0.5259216053983014 | [32] | [83] | 5 | hSpCas9 | negative selection | 10777859 | 112206717 | 112206740 | 7 | + | 28162770 | SKM1 | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | 0.11176460357790763 | [77] | [148] | 1 | hSpCas9 | negative selection | 10777860 | 112206770 | 112206793 | 7 | + | 28162770 | SKM1 | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | 1.043068721891886 | [27] | [101] | 8 | hSpCas9 | negative selection | 10777861 | 112206750 | 112206773 | 7 | + | 28162770 | SKM1 | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | 0.5374584533619582 | [128] | [330] | 5 | hSpCas9 | negative selection | 10777862 | 112286927 | 112286950 | 7 | - | 28162770 | SKM1 | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.4536327445914221 | [170] | [413] | 4 | hSpCas9 | negative selection | 10777863 | 112296290 | 112296313 | 7 | + | 28162770 | SKM1 | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 0.11386796455827874 | [68] | [131] | 1 | hSpCas9 | negative selection | 10777864 | 112286896 | 112286919 | 7 | - | 28162770 | SKM1 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | -0.28878277239484773 | [122] | [177] | -2 | hSpCas9 | negative selection | 10777865 | 112295943 | 112295966 | 7 | - | 28162770 | PL21 | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.02505290793122894 | [69] | [30] | 0 | hSpCas9 | negative selection | 10947224 | 112286947 | 112286970 | 7 | - | 28162770 | PL21 | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | 0.1731725668890507 | [107] | [52] | 1 | hSpCas9 | negative selection | 10947225 | 112206717 | 112206740 | 7 | + | 28162770 | PL21 | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | 0.3214459107114539 | [284] | [154] | 3 | hSpCas9 | negative selection | 10947226 | 112206770 | 112206793 | 7 | + | 28162770 | PL21 | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | -0.034325639147702924 | [119] | [50] | 0 | hSpCas9 | negative selection | 10947227 | 112206750 | 112206773 | 7 | + | 28162770 | PL21 | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | 0.16061125030268264 | [369] | [179] | 1 | hSpCas9 | negative selection | 10947228 | 112286927 | 112286950 | 7 | - | 28162770 | PL21 | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | -0.6042680235179471 | [488] | [139] | -4 | hSpCas9 | negative selection | 10947229 | 112296290 | 112296313 | 7 | + | 28162770 | PL21 | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 0.45167838148528455 | [167] | [99] | 4 | hSpCas9 | negative selection | 10947230 | 112286896 | 112286919 | 7 | - | 28162770 | PL21 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | 0.12378872835920562 | [387] | [183] | 1 | hSpCas9 | negative selection | 10947231 | 112295943 | 112295966 | 7 | - | 28162770 | P31FUJ | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | -1.2328022044143785 | [77] | [38] | -7 | hSpCas9 | negative selection | 11116590 | 112286947 | 112286970 | 7 | - | 28162770 | P31FUJ | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | -1.0093639729263797 | [196] | [114] | -6 | hSpCas9 | negative selection | 11116591 | 112206717 | 112206740 | 7 | + | 28162770 | P31FUJ | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | -0.4005296501524451 | [245] | [218] | -4 | hSpCas9 | negative selection | 11116592 | 112206770 | 112206793 | 7 | + | 28162770 | P31FUJ | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | -0.11732498699444271 | [131] | [142] | -1 | hSpCas9 | negative selection | 11116593 | 112206750 | 112206773 | 7 | + | 28162770 | P31FUJ | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | -0.26109124884580215 | [514] | [504] | -2 | hSpCas9 | negative selection | 11116594 | 112286927 | 112286950 | 7 | - | 28162770 | P31FUJ | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | -0.6343941726282707 | [711] | [538] | -5 | hSpCas9 | negative selection | 11116595 | 112296290 | 112296313 | 7 | + | 28162770 | P31FUJ | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 0.6329694038685474 | [241] | [440] | 7 | hSpCas9 | negative selection | 11116596 | 112286896 | 112286919 | 7 | - | 28162770 | P31FUJ | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | -0.4331553774920377 | [562] | [489] | -4 | hSpCas9 | negative selection | 11116597 | 112295943 | 112295966 | 7 | - | 28162770 | OCIAML5 | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 1.8951673587560358 | [6] | [46] | 9 | hSpCas9 | negative selection | 11285956 | 112286947 | 112286970 | 7 | - | 28162770 | OCIAML5 | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | 0.10113921765706194 | [93] | [181] | 0 | hSpCas9 | negative selection | 11285957 | 112206717 | 112206740 | 7 | + | 28162770 | OCIAML5 | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | 0.6100391820716258 | [97] | [269] | 5 | hSpCas9 | negative selection | 11285958 | 112206770 | 112206793 | 7 | + | 28162770 | OCIAML5 | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | 1.6218646174684155 | [44] | [249] | 9 | hSpCas9 | negative selection | 11285959 | 112206750 | 112206773 | 7 | + | 28162770 | OCIAML5 | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | 0.45583196411930715 | [247] | [613] | 4 | hSpCas9 | negative selection | 11285960 | 112286927 | 112286950 | 7 | - | 28162770 | OCIAML5 | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.3236687285683164 | [412] | [932] | 2 | hSpCas9 | negative selection | 11285961 | 112296290 | 112296313 | 7 | + | 28162770 | OCIAML5 | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 0.9511878414481388 | [150] | [526] | 8 | hSpCas9 | negative selection | 11285962 | 112286896 | 112286919 | 7 | - | 28162770 | OCIAML5 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | 0.5599111286657887 | [235] | [627] | 5 | hSpCas9 | negative selection | 11285963 | 112295943 | 112295966 | 7 | - | 28162770 | EOL1 | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.4928315311450604 | [115] | [85] | 4 | hSpCas9 | negative selection | 11455322 | 112286947 | 112286970 | 7 | - | 28162770 | EOL1 | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | 1.6631899435441242 | [171] | [286] | 9 | hSpCas9 | negative selection | 11455323 | 112206717 | 112206740 | 7 | + | 28162770 | EOL1 | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | 0.61747280477753 | [458] | [370] | 5 | hSpCas9 | negative selection | 11455324 | 112206770 | 112206793 | 7 | + | 28162770 | EOL1 | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | 0.5217886020701274 | [233] | [176] | 5 | hSpCas9 | negative selection | 11455325 | 112206750 | 112206773 | 7 | + | 28162770 | EOL1 | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | 0.10331326050672451 | [469] | [265] | 0 | hSpCas9 | negative selection | 11455326 | 112286927 | 112286950 | 7 | - | 28162770 | EOL1 | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.13946429763719648 | [690] | [400] | 1 | hSpCas9 | negative selection | 11455327 | 112296290 | 112296313 | 7 | + | 28162770 | EOL1 | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 0.6712613422883029 | [235] | [197] | 6 | hSpCas9 | negative selection | 11455328 | 112286896 | 112286919 | 7 | - | 28162770 | EOL1 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | 0.28217202835044075 | [486] | [311] | 2 | hSpCas9 | negative selection | 11455329 | 112295943 | 112295966 | 7 | - | 28162770 | MOLM13 | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.9824625543743369 | [83] | [119] | 7 | hSpCas9 | negative selection | 11624688 | 112286947 | 112286970 | 7 | - | 28162770 | MOLM13 | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | 0.5984734913547232 | [189] | [207] | 4 | hSpCas9 | negative selection | 11624689 | 112206717 | 112206740 | 7 | + | 28162770 | MOLM13 | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | -0.19429262163847283 | [306] | [193] | -1 | hSpCas9 | negative selection | 11624690 | 112206770 | 112206793 | 7 | + | 28162770 | MOLM13 | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | -0.642293536205844 | [135] | [62] | -4 | hSpCas9 | negative selection | 11624691 | 112206750 | 112206773 | 7 | + | 28162770 | MOLM13 | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | -0.8333676343051334 | [588] | [238] | -4 | hSpCas9 | negative selection | 11624692 | 112286927 | 112286950 | 7 | - | 28162770 | MOLM13 | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.31377554150372133 | [759] | [682] | 2 | hSpCas9 | negative selection | 11624693 | 112296290 | 112296313 | 7 | + | 28162770 | MOLM13 | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 0.5049787002797987 | [383] | [393] | 4 | hSpCas9 | negative selection | 11624694 | 112286896 | 112286919 | 7 | - | 28162770 | MOLM13 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | 1.0077921596470834 | [541] | [787] | 7 | hSpCas9 | negative selection | 11624695 | 112295943 | 112295966 | 7 | - | 28162770 | HEL | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 0.3242093135748595 | [105] | [84] | 2 | hSpCas9 | negative selection | 11794054 | 112286947 | 112286970 | 7 | - | 28162770 | HEL | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | 0.22495072170547845 | [174] | [130] | 1 | hSpCas9 | negative selection | 11794055 | 112206717 | 112206740 | 7 | + | 28162770 | HEL | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | 0.5057021243169084 | [308] | [280] | 4 | hSpCas9 | negative selection | 11794056 | 112206770 | 112206793 | 7 | + | 28162770 | HEL | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | 0.3030464576371551 | [142] | [112] | 2 | hSpCas9 | negative selection | 11794057 | 112206750 | 112206773 | 7 | + | 28162770 | HEL | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | -0.4155063090355964 | [555] | [266] | -3 | hSpCas9 | negative selection | 11794058 | 112286927 | 112286950 | 7 | - | 28162770 | HEL | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | -0.7913106358042903 | [661] | [244] | -5 | hSpCas9 | negative selection | 11794059 | 112296290 | 112296313 | 7 | + | 28162770 | HEL | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 0.758216049420293 | [215] | [233] | 6 | hSpCas9 | negative selection | 11794060 | 112286896 | 112286919 | 7 | - | 28162770 | HEL | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | 0.4275329512571784 | [533] | [459] | 3 | hSpCas9 | negative selection | 11794061 | 112295943 | 112295966 | 7 | - | 28162770 | MV411 | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 1.6086250761173648 | [57] | [148] | 9 | hSpCas9 | negative selection | 11963420 | 112286947 | 112286970 | 7 | - | 28162770 | MV411 | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | 0.15297286677928282 | [141] | [132] | 1 | hSpCas9 | negative selection | 11963421 | 112206717 | 112206740 | 7 | + | 28162770 | MV411 | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | 0.0009543212128293455 | [311] | [262] | 0 | hSpCas9 | negative selection | 11963422 | 112206770 | 112206793 | 7 | + | 28162770 | MV411 | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | -0.009950291909876507 | [152] | [127] | 0 | hSpCas9 | negative selection | 11963423 | 112206750 | 112206773 | 7 | + | 28162770 | MV411 | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | 0.6160821445771679 | [315] | [407] | 5 | hSpCas9 | negative selection | 11963424 | 112286927 | 112286950 | 7 | - | 28162770 | MV411 | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.47257534885804064 | [449] | [525] | 4 | hSpCas9 | negative selection | 11963425 | 112296290 | 112296313 | 7 | + | 28162770 | MV411 | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 1.1711341834695779 | [164] | [312] | 9 | hSpCas9 | negative selection | 11963426 | 112286896 | 112286919 | 7 | - | 28162770 | MV411 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | -0.23511394899645732 | [400] | [286] | -2 | hSpCas9 | negative selection | 11963427 | 112295943 | 112295966 | 7 | - | 28162770 | MONOMAC1 | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | -1.1653279873322153 | [44] | [22] | -7 | hSpCas9 | negative selection | 12132786 | 112286947 | 112286970 | 7 | - | 28162770 | MONOMAC1 | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | 0.22286640739110608 | [73] | [98] | 2 | hSpCas9 | negative selection | 12132787 | 112206717 | 112206740 | 7 | + | 28162770 | MONOMAC1 | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | 0.07598164734686219 | [167] | [202] | 0 | hSpCas9 | negative selection | 12132788 | 112206770 | 112206793 | 7 | + | 28162770 | MONOMAC1 | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | 0.2742688718660354 | [87] | [121] | 2 | hSpCas9 | negative selection | 12132789 | 112206750 | 112206773 | 7 | + | 28162770 | MONOMAC1 | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | 0.5282469420590172 | [247] | [409] | 5 | hSpCas9 | negative selection | 12132790 | 112286927 | 112286950 | 7 | - | 28162770 | MONOMAC1 | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.32261005899407613 | [368] | [528] | 3 | hSpCas9 | negative selection | 12132791 | 112296290 | 112296313 | 7 | + | 28162770 | MONOMAC1 | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 0.10104450587344097 | [121] | [149] | 1 | hSpCas9 | negative selection | 12132792 | 112286896 | 112286919 | 7 | - | 28162770 | MONOMAC1 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | -0.4370879348925082 | [273] | [231] | -4 | hSpCas9 | negative selection | 12132793 | 112295943 | 112295966 | 7 | - | 28162770 | OCIAML2 | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 1.5675053036446096 | [6] | [114] | 9 | hSpCas9 | negative selection | 12302152 | 112286947 | 112286970 | 7 | - | 28162770 | OCIAML2 | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | 1.470817992402726 | [10] | [168] | 9 | hSpCas9 | negative selection | 12302153 | 112206717 | 112206740 | 7 | + | 28162770 | OCIAML2 | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | -0.16077456265537377 | [47] | [237] | -1 | hSpCas9 | negative selection | 12302154 | 112206770 | 112206793 | 7 | + | 28162770 | OCIAML2 | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | 0.5753825725146748 | [26] | [222] | 5 | hSpCas9 | negative selection | 12302155 | 112206750 | 112206773 | 7 | + | 28162770 | OCIAML2 | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | 0.2489187158466355 | [74] | [493] | 2 | hSpCas9 | negative selection | 12302156 | 112286927 | 112286950 | 7 | - | 28162770 | OCIAML2 | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.4032205086023499 | [105] | [776] | 4 | hSpCas9 | negative selection | 12302157 | 112296290 | 112296313 | 7 | + | 28162770 | OCIAML2 | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | 0.1526026924067124 | [30] | [190] | 1 | hSpCas9 | negative selection | 12302158 | 112286896 | 112286919 | 7 | - | 28162770 | OCIAML2 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | -0.18997800593331793 | [77] | [378] | -1 | hSpCas9 | negative selection | 12302159 | 112295943 | 112295966 | 7 | - | 28162770 | OCIAML3 | viability | ACACTTACCAAATGGAGCAGTGG | ZNF277 | ENSG00000198839 | 1.6189860830100349 | [10] | [101] | 9 | hSpCas9 | negative selection | 12471518 | 112286947 | 112286970 | 7 | - | 28162770 | OCIAML3 | viability | CAGAAAATACAAGGCACAGATGG | ZNF277 | ENSG00000198839 | -0.12622867897334605 | [46] | [129] | -1 | hSpCas9 | negative selection | 12471519 | 112206717 | 112206740 | 7 | + | 28162770 | OCIAML3 | viability | ATGGCTGCTTCCAAGACCCAGGG | ZNF277 | ENSG00000198839 | 0.9639878127967236 | [71] | [423] | 8 | hSpCas9 | negative selection | 12471520 | 112206770 | 112206793 | 7 | + | 28162770 | OCIAML3 | viability | TGGGAGCTGCAGCACAGTCGGGG | ZNF277 | ENSG00000198839 | -0.3511511164279997 | [29] | [70] | -3 | hSpCas9 | negative selection | 12471521 | 112206750 | 112206773 | 7 | + | 28162770 | OCIAML3 | viability | CGAATGCAGGAAGACCGTGATGG | ZNF277 | ENSG00000198839 | 0.09925447574388202 | [123] | [400] | 0 | hSpCas9 | negative selection | 12471522 | 112286927 | 112286950 | 7 | - | 28162770 | OCIAML3 | viability | TGGAGAACCTTCTAAAGTGGTGG | ZNF277 | ENSG00000198839 | 0.11721863304316571 | [163] | [536] | 1 | hSpCas9 | negative selection | 12471523 | 112296290 | 112296313 | 7 | + | 28162770 | OCIAML3 | viability | AGAGCTTCAGAAACAGAGACTGG | ZNF277 | ENSG00000198839 | -0.2771505349842228 | [56] | [141] | -2 | hSpCas9 | negative selection | 12471524 | 112286896 | 112286919 | 7 | - | 28162770 | OCIAML3 | viability | GGACTTTCTGGCAGGGAAAGCGG | ZNF277 | ENSG00000198839 | 0.08252209998006887 | [116] | [373] | 0 | hSpCas9 | negative selection | 12471525 |