Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:84215
• Symbol:ZNF541
• Description:zinc finger protein 541

DataSource: http://genomecrispr.dkfz.de/#!/results/ZNF541

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
47538443	47538466	19	+	26472758	Jiyoye	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	-0.7183555005779855	[71]	[32]	-5	hSpCas9	negative selection	188156
47545520	47545543	19	-	26472758	Jiyoye	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.3585952010608118	[150]	[145]	2	hSpCas9	negative selection	188157
47538418	47538441	19	-	26472758	Jiyoye	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	1.0525105002065112	[38]	[60]	7	hSpCas9	negative selection	188158
47521859	47521882	19	-	26472758	Jiyoye	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-3.4727481665023756	[264]	[17]	-9	hSpCas9	negative selection	188159
47555784	47555807	19	+	26472758	Jiyoye	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	3.272245801419765	[20]	[152]	9	hSpCas9	negative selection	188160
47549424	47549447	19	-	26472758	Jiyoye	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	0.8189001467438815	[108]	[144]	6	hSpCas9	negative selection	188161
47549403	47549426	19	-	26472758	Jiyoye	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-3.228413192285251	[173]	[13]	-9	hSpCas9	negative selection	188162
47549351	47549374	19	-	26472758	Jiyoye	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	-1.5562987424690127	[38]	[9]	-7	hSpCas9	negative selection	188163
47545620	47545643	19	-	26472758	Jiyoye	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	1.7941985046151205	[25]	[67]	8	hSpCas9	negative selection	188164
47545578	47545601	19	+	26472758	Jiyoye	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-2.2102085969076604	[134]	[21]	-8	hSpCas9	negative selection	188165
47538443	47538466	19	+	26472758	KBM7	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	0.5956527006589332	[110,53]	[59,53]	6	hSpCas9	negative selection	379274
47545520	47545543	19	-	26472758	KBM7	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	1.4550872171899574	[542,467]	[840,478]	9	hSpCas9	negative selection	379275
47538418	47538441	19	-	26472758	KBM7	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-0.6560731308712229	[442,275]	[128,83]	-5	hSpCas9	negative selection	379276
47521859	47521882	19	-	26472758	KBM7	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-3.320719619579316	[1279,980]	[85,22]	-9	hSpCas9	negative selection	379277
47555784	47555807	19	+	26472758	KBM7	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	0.9278649845937129	[231,160]	[203,145]	8	hSpCas9	negative selection	379278
47549424	47549447	19	-	26472758	KBM7	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	0.5672413155514926	[455,339]	[302,248]	6	hSpCas9	negative selection	379279
47549403	47549426	19	-	26472758	KBM7	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-1.5993707411334666	[465,428]	[116,26]	-8	hSpCas9	negative selection	379280
47549351	47549374	19	-	26472758	KBM7	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	-0.12053689435033088	[162,136]	[52,74]	-1	hSpCas9	negative selection	379281
47545620	47545643	19	-	26472758	KBM7	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	-0.13969011732825098	[83,81]	[43,27]	-1	hSpCas9	negative selection	379282
47545578	47545601	19	+	26472758	KBM7	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-1.0200885960781179	[398,279]	[111,46]	-7	hSpCas9	negative selection	379283
47538443	47538466	19	+	26472758	Raji	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	-0.682693395252169	[82]	[11]	-5	hSpCas9	negative selection	570392
47545520	47545543	19	-	26472758	Raji	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.6953298945335772	[321]	[120]	6	hSpCas9	negative selection	570393
47538418	47538441	19	-	26472758	Raji	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-0.7486061619348812	[180]	[24]	-5	hSpCas9	negative selection	570394
47521859	47521882	19	-	26472758	Raji	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-4.504870657015297	[586]	[5]	-9	hSpCas9	negative selection	570395
47555784	47555807	19	+	26472758	Raji	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	-0.4191622791222346	[241]	[41]	-3	hSpCas9	negative selection	570396
47549424	47549447	19	-	26472758	Raji	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	0.9553804419285495	[139]	[62]	8	hSpCas9	negative selection	570397
47549403	47549426	19	-	26472758	Raji	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-2.4161784206834134	[229]	[9]	-9	hSpCas9	negative selection	570398
47549351	47549374	19	-	26472758	Raji	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	-3.593056182767493	[51]	[0]	-9	hSpCas9	negative selection	570399
47545620	47545643	19	-	26472758	Raji	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	-0.6340834510275475	[106]	[15]	-5	hSpCas9	negative selection	570400
47545578	47545601	19	+	26472758	Raji	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-0.5999755967072834	[208]	[31]	-5	hSpCas9	negative selection	570401
47538443	47538466	19	+	26472758	K562	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	-0.5369409858582128	[109]	[63]	-3	hSpCas9	negative selection	761510
47545520	47545543	19	-	26472758	K562	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.2860532163744106	[443]	[456]	2	hSpCas9	negative selection	761511
47538418	47538441	19	-	26472758	K562	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-0.4129796091814407	[193]	[122]	-3	hSpCas9	negative selection	761512
47521859	47521882	19	-	26472758	K562	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-4.294361671625412	[952]	[40]	-9	hSpCas9	negative selection	761513
47555784	47555807	19	+	26472758	K562	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	0.4923462411100322	[303]	[360]	4	hSpCas9	negative selection	761514
47549424	47549447	19	-	26472758	K562	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	-0.1895359849550269	[434]	[321]	-1	hSpCas9	negative selection	761515
47549403	47549426	19	-	26472758	K562	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-2.8240610102163197	[452]	[53]	-8	hSpCas9	negative selection	761516
47549351	47549374	19	-	26472758	K562	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	-0.7555812723335529	[71]	[35]	-4	hSpCas9	negative selection	761517
47545620	47545643	19	-	26472758	K562	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	1.1119684316427976	[113]	[207]	8	hSpCas9	negative selection	761518
47545578	47545601	19	+	26472758	K562	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-1.3272469504412514	[323]	[108]	-6	hSpCas9	negative selection	761519
47539687	47539710	19	+	26627737	DLD1	viability	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	-0.3060414375073852	[1399]	[416,415,247]	-3	hSpCas9	negative selection	805762
47540293	47540316	19	-	26627737	DLD1	viability	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	-0.6455625338086287	[1062]	[230,248,165]	-6	hSpCas9	negative selection	805763
47540906	47540929	19	+	26627737	DLD1	viability	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.3928223247528781	[510]	[178,249,202]	4	hSpCas9	negative selection	805764
47545923	47545946	19	+	26627737	DLD1	viability	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	-0.16727504336039123	[929]	[202,280,288]	-2	hSpCas9	negative selection	805765
47549252	47549275	19	-	26627737	DLD1	viability	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	0.1722328782485305	[258]	[73,88,107]	1	hSpCas9	negative selection	805766
47555752	47555775	19	-	26627737	DLD1	viability	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-0.059282464782757505	[572]	[170,214,136]	0	hSpCas9	negative selection	805767
47539687	47539710	19	+	26627737	GBM cells	viability after 5 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.18235449138131665	[584]	[296,414]	3	hSpCas9	negative selection	888077
47540293	47540316	19	-	26627737	GBM cells	viability after 5 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.34804457283293744	[344]	[228,241]	5	hSpCas9	negative selection	888078
47540906	47540929	19	+	26627737	GBM cells	viability after 5 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.21494136833336383	[195]	[130,112]	3	hSpCas9	negative selection	888079
47545923	47545946	19	+	26627737	GBM cells	viability after 5 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	0.13567458651037073	[313]	[220,148]	2	hSpCas9	negative selection	888080
47549252	47549275	19	-	26627737	GBM cells	viability after 5 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	0.8405698886548807	[163]	[159,154]	9	hSpCas9	negative selection	888081
47555752	47555775	19	-	26627737	GBM cells	viability after 5 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	0.22618953495641647	[376]	[270,201]	3	hSpCas9	negative selection	888082
47539687	47539710	19	+	26627737	GBM cells	viability after 13 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.1655139418681124	[584]	[414,307]	2	hSpCas9	negative selection	970392
47540293	47540316	19	-	26627737	GBM cells	viability after 13 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.5783929979304823	[344]	[257,296]	7	hSpCas9	negative selection	970393
47540906	47540929	19	+	26627737	GBM cells	viability after 13 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.7394867789157336	[195]	[176,177]	8	hSpCas9	negative selection	970394
47545923	47545946	19	+	26627737	GBM cells	viability after 13 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	-0.020579111280100537	[313]	[221,123]	0	hSpCas9	negative selection	970395
47549252	47549275	19	-	26627737	GBM cells	viability after 13 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	0.67869909017853	[163]	[185,106]	8	hSpCas9	negative selection	970396
47555752	47555775	19	-	26627737	GBM cells	viability after 13 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	0.7079582809555538	[376]	[471,221]	8	hSpCas9	negative selection	970397
47539687	47539710	19	+	26627737	GBM cells	viability after 21 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.12580812562178934	[584]	[351,341]	1	hSpCas9	negative selection	1052707
47540293	47540316	19	-	26627737	GBM cells	viability after 21 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.7515817591266871	[344]	[313,316]	7	hSpCas9	negative selection	1052708
47540906	47540929	19	+	26627737	GBM cells	viability after 21 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.3625020918709877	[195]	[150,123]	4	hSpCas9	negative selection	1052709
47545923	47545946	19	+	26627737	GBM cells	viability after 21 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	-0.6412116031474835	[313]	[123,95]	-5	hSpCas9	negative selection	1052710
47549252	47549275	19	-	26627737	GBM cells	viability after 21 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	0.5279315556847772	[163]	[140,116]	5	hSpCas9	negative selection	1052711
47555752	47555775	19	-	26627737	GBM cells	viability after 21 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-0.15157950101701834	[376]	[186,181]	-1	hSpCas9	negative selection	1052712
47539687	47539710	19	+	26627737	RPE1	viability after 9 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	-0.6174069980438917	[2745]	[438,716]	-4	hSpCas9	negative selection	1135022
47540293	47540316	19	-	26627737	RPE1	viability after 9 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	-0.7456897890585592	[748]	[124,158]	-5	hSpCas9	negative selection	1135023
47540906	47540929	19	+	26627737	RPE1	viability after 9 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.16877672438538602	[666]	[132,365]	1	hSpCas9	negative selection	1135024
47545923	47545946	19	+	26627737	RPE1	viability after 9 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	0.9631721434992924	[822]	[321,734]	6	hSpCas9	negative selection	1135025
47549252	47549275	19	-	26627737	RPE1	viability after 9 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	2.5699458265553687	[73]	[106,176]	9	hSpCas9	negative selection	1135026
47555752	47555775	19	-	26627737	RPE1	viability after 9 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-2.2400922180725953	[1684]	[67,167]	-9	hSpCas9	negative selection	1135027
47539687	47539710	19	+	26627737	RPE1	viability after 12 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	-0.3241810165110266	[2745]	[666,506]	-2	hSpCas9	negative selection	1217337
47540293	47540316	19	-	26627737	RPE1	viability after 12 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.033990112922146015	[748]	[104,312]	0	hSpCas9	negative selection	1217338
47540906	47540929	19	+	26627737	RPE1	viability after 12 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.6263748224044421	[666]	[212,343]	4	hSpCas9	negative selection	1217339
47545923	47545946	19	+	26627737	RPE1	viability after 12 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	0.8087236957905399	[822]	[329,447]	5	hSpCas9	negative selection	1217340
47549252	47549275	19	-	26627737	RPE1	viability after 12 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	2.918770562265111	[73]	[76,227]	9	hSpCas9	negative selection	1217341
47555752	47555775	19	-	26627737	RPE1	viability after 12 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-1.182486485214545	[1684]	[129,272]	-7	hSpCas9	negative selection	1217342
47539687	47539710	19	+	26627737	RPE1	viability after 15 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	-0.17643127208494103	[2745]	[722,652]	-1	hSpCas9	negative selection	1299652
47540293	47540316	19	-	26627737	RPE1	viability after 15 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.3038561976770927	[748]	[61,453]	2	hSpCas9	negative selection	1299653
47540906	47540929	19	+	26627737	RPE1	viability after 15 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.36014777018813104	[666]	[231,251]	2	hSpCas9	negative selection	1299654
47545923	47545946	19	+	26627737	RPE1	viability after 15 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	0.6238853148078307	[822]	[343,372]	4	hSpCas9	negative selection	1299655
47549252	47549275	19	-	26627737	RPE1	viability after 15 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	2.377512218001555	[73]	[36,177]	9	hSpCas9	negative selection	1299656
47555752	47555775	19	-	26627737	RPE1	viability after 15 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-1.3774501694455448	[1684]	[44,316]	-7	hSpCas9	negative selection	1299657
47539687	47539710	19	+	26627737	RPE1	viability after 18 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	-0.41871846903340515	[2745]	[579,526]	-3	hSpCas9	negative selection	1381967
47540293	47540316	19	-	26627737	RPE1	viability after 18 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.658023173130306	[748]	[127,522]	4	hSpCas9	negative selection	1381968
47540906	47540929	19	+	26627737	RPE1	viability after 18 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.6613351290278879	[666]	[187,387]	4	hSpCas9	negative selection	1381969
47545923	47545946	19	+	26627737	RPE1	viability after 18 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	1.1994607581366155	[822]	[511,507]	6	hSpCas9	negative selection	1381970
47549252	47549275	19	-	26627737	RPE1	viability after 18 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	2.3977126566190825	[73]	[82,128]	9	hSpCas9	negative selection	1381971
47555752	47555775	19	-	26627737	RPE1	viability after 18 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-2.0408073721718156	[1684]	[37,187]	-8	hSpCas9	negative selection	1381972
47539687	47539710	19	+	26627737	HeLa	viability after 8 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.303095434221063	[991]	[316,607,618]	3	hSpCas9	negative selection	1464282
47540293	47540316	19	-	26627737	HeLa	viability after 8 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.8484596601836699	[353]	[311,165,355]	7	hSpCas9	negative selection	1464283
47540906	47540929	19	+	26627737	HeLa	viability after 8 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	1.3757160213897566	[160]	[239,177,142]	8	hSpCas9	negative selection	1464284
47545923	47545946	19	+	26627737	HeLa	viability after 8 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	-0.27696303901991504	[852]	[232,246,414]	-3	hSpCas9	negative selection	1464285
47549252	47549275	19	-	26627737	HeLa	viability after 8 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	-0.08277412675334554	[383]	[168,77,223]	0	hSpCas9	negative selection	1464286
47555752	47555775	19	-	26627737	HeLa	viability after 8 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	0.5314298093966532	[492]	[303,242,376]	5	hSpCas9	negative selection	1464287
47539687	47539710	19	+	26627737	HeLa	viability after 12 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.18393764748744168	[991]	[487,538,362]	1	hSpCas9	negative selection	1546597
47540293	47540316	19	-	26627737	HeLa	viability after 12 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	1.1086792179308282	[353]	[203,392,337]	7	hSpCas9	negative selection	1546598
47540906	47540929	19	+	26627737	HeLa	viability after 12 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	1.256979409165725	[160]	[153,176,143]	8	hSpCas9	negative selection	1546599
47545923	47545946	19	+	26627737	HeLa	viability after 12 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	0.2694758930340342	[852]	[370,350,558]	2	hSpCas9	negative selection	1546600
47549252	47549275	19	-	26627737	HeLa	viability after 12 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	0.29639070926152217	[383]	[267,173,146]	2	hSpCas9	negative selection	1546601
47555752	47555775	19	-	26627737	HeLa	viability after 12 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	0.599704193979912	[492]	[433,184,323]	5	hSpCas9	negative selection	1546602
47539687	47539710	19	+	26627737	HeLa	viability after 15 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.6193925796891737	[991]	[670,611,573]	5	hSpCas9	negative selection	1628912
47540293	47540316	19	-	26627737	HeLa	viability after 15 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.8858328547429626	[353]	[133,310,362]	6	hSpCas9	negative selection	1628913
47540906	47540929	19	+	26627737	HeLa	viability after 15 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.9415540940071323	[160]	[138,57,184]	7	hSpCas9	negative selection	1628914
47545923	47545946	19	+	26627737	HeLa	viability after 15 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	0.19979350316252242	[852]	[463,340,389]	1	hSpCas9	negative selection	1628915
47549252	47549275	19	-	26627737	HeLa	viability after 15 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	0.05935130947435631	[383]	[134,94,266]	0	hSpCas9	negative selection	1628916
47555752	47555775	19	-	26627737	HeLa	viability after 15 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	1.2786204608418488	[492]	[669,438,337]	8	hSpCas9	negative selection	1628917
47539687	47539710	19	+	26627737	HeLa	viability after 18 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.6334065065326226	[991]	[460,507,573]	5	hSpCas9	negative selection	1711227
47540293	47540316	19	-	26627737	HeLa	viability after 18 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.8251895562910601	[353]	[72,251,362]	6	hSpCas9	negative selection	1711228
47540906	47540929	19	+	26627737	HeLa	viability after 18 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.9748398625908212	[160]	[94,52,184]	7	hSpCas9	negative selection	1711229
47545923	47545946	19	+	26627737	HeLa	viability after 18 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	0.22081251848576255	[852]	[310,296,389]	1	hSpCas9	negative selection	1711230
47549252	47549275	19	-	26627737	HeLa	viability after 18 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	0.058847720096873876	[383]	[90,77,266]	0	hSpCas9	negative selection	1711231
47555752	47555775	19	-	26627737	HeLa	viability after 18 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	1.315686455208616	[492]	[468,369,337]	8	hSpCas9	negative selection	1711232
47539687	47539710	19	+	26627737	HCT116	viability after 6 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.7316184519349513	[1436]	[601,249]	4	hSpCas9	negative selection	1793542
47540293	47540316	19	-	26627737	HCT116	viability after 6 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.6596886218141802	[1011]	[153,304]	3	hSpCas9	negative selection	1793543
47540906	47540929	19	+	26627737	HCT116	viability after 6 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.7400793015888175	[249]	[64,65]	4	hSpCas9	negative selection	1793544
47545923	47545946	19	+	26627737	HCT116	viability after 6 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	0.6562536881047888	[874]	[433,96]	3	hSpCas9	negative selection	1793545
47549252	47549275	19	-	26627737	HCT116	viability after 6 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	-0.3697096480884089	[490]	[22,79]	-2	hSpCas9	negative selection	1793546
47555752	47555775	19	-	26627737	HCT116	viability after 6 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-0.05183893151961816	[466]	[191,3]	0	hSpCas9	negative selection	1793547
47539687	47539710	19	+	26627737	HCT116	viability after 8 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.20047441474854777	[671]	[364,369,538]	2	hSpCas9	negative selection	1875857
47540293	47540316	19	-	26627737	HCT116	viability after 8 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	1.0069030949242168	[267]	[230,185,469]	8	hSpCas9	negative selection	1875858
47540906	47540929	19	+	26627737	HCT116	viability after 8 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	1.3875637181812615	[95]	[60,228,123]	9	hSpCas9	negative selection	1875859
47545923	47545946	19	+	26627737	HCT116	viability after 8 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	0.4425895081399428	[332]	[192,212,339]	4	hSpCas9	negative selection	1875860
47549252	47549275	19	-	26627737	HCT116	viability after 8 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	-0.7060621662900585	[212]	[100,13,100]	-7	hSpCas9	negative selection	1875861
47555752	47555775	19	-	26627737	HCT116	viability after 8 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-0.3254239800692268	[640]	[198,266,376]	-4	hSpCas9	negative selection	1875862
47539687	47539710	19	+	26627737	HCT116	viability after 9 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.545196369373236	[1436]	[555,562]	4	hSpCas9	negative selection	1958172
47540293	47540316	19	-	26627737	HCT116	viability after 9 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.5346157229478223	[1011]	[310,454]	4	hSpCas9	negative selection	1958173
47540906	47540929	19	+	26627737	HCT116	viability after 9 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.5615871879473356	[249]	[21,158]	4	hSpCas9	negative selection	1958174
47545923	47545946	19	+	26627737	HCT116	viability after 9 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	1.2397156297973293	[874]	[267,775]	7	hSpCas9	negative selection	1958175
47549252	47549275	19	-	26627737	HCT116	viability after 9 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	0.4215892378809853	[490]	[83,247]	3	hSpCas9	negative selection	1958176
47555752	47555775	19	-	26627737	HCT116	viability after 9 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	0.8249077251907504	[466]	[240,204]	6	hSpCas9	negative selection	1958177
47539687	47539710	19	+	26627737	HCT116	viability after 12 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.14045360050228672	[671]	[379,322,463]	1	hSpCas9	negative selection	2040487
47540293	47540316	19	-	26627737	HCT116	viability after 12 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	1.1060108653507212	[267]	[330,342,233]	8	hSpCas9	negative selection	2040488
47540906	47540929	19	+	26627737	HCT116	viability after 12 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.8582418833046409	[95]	[79,116,78]	7	hSpCas9	negative selection	2040489
47545923	47545946	19	+	26627737	HCT116	viability after 12 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	1.0274840343438756	[332]	[491,219,342]	8	hSpCas9	negative selection	2040490
47549252	47549275	19	-	26627737	HCT116	viability after 12 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	-0.5682535784190118	[212]	[39,91,97]	-6	hSpCas9	negative selection	2040491
47555752	47555775	19	-	26627737	HCT116	viability after 12 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-0.6021385086695717	[640]	[282,205,170]	-6	hSpCas9	negative selection	2040492
47539687	47539710	19	+	26627737	HCT116	viability after 15 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.24893335546975104	[671]	[496,383,498]	2	hSpCas9	negative selection	2122802
47540293	47540316	19	-	26627737	HCT116	viability after 15 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.48561792494912404	[267]	[282,178,192]	4	hSpCas9	negative selection	2122803
47540906	47540929	19	+	26627737	HCT116	viability after 15 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	1.4336869247075041	[95]	[51,233,148]	9	hSpCas9	negative selection	2122804
47545923	47545946	19	+	26627737	HCT116	viability after 15 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	0.7709280159026268	[332]	[478,228,289]	6	hSpCas9	negative selection	2122805
47549252	47549275	19	-	26627737	HCT116	viability after 15 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	-0.0340961361442097	[212]	[111,84,159]	0	hSpCas9	negative selection	2122806
47555752	47555775	19	-	26627737	HCT116	viability after 15 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-0.3441081972520733	[640]	[254,257,351]	-4	hSpCas9	negative selection	2122807
47539687	47539710	19	+	26627737	HCT116	viability after 18 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.5689896171453885	[671]	[459,446,543]	5	hSpCas9	negative selection	2205117
47540293	47540316	19	-	26627737	HCT116	viability after 18 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.8250104912424553	[267]	[248,140,307]	6	hSpCas9	negative selection	2205118
47540906	47540929	19	+	26627737	HCT116	viability after 18 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.8917077278689156	[95]	[62,106,86]	7	hSpCas9	negative selection	2205119
47545923	47545946	19	+	26627737	HCT116	viability after 18 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	0.6161344309273653	[332]	[423,124,196]	5	hSpCas9	negative selection	2205120
47549252	47549275	19	-	26627737	HCT116	viability after 18 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	0.33376178657895894	[212]	[135,112,141]	3	hSpCas9	negative selection	2205121
47555752	47555775	19	-	26627737	HCT116	viability after 18 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-0.45544225024134843	[640]	[210,274,186]	-4	hSpCas9	negative selection	2205122
47555719	47555742	19	+	24336569	HL60	viability	ATAAAGAAAGCCTCGCGTGTTGG	ZNF541	ENSG00000118156	-1.393848422845388	[338]	[272]	-8	hSpCas9	negative selection	2311187
47555729	47555752	19	-	24336569	HL60	viability	GATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	0.4838361531152239	[196]	[582]	4	hSpCas9	negative selection	2311188
47555739	47555762	19	+	24336569	HL60	viability	TGGGACCCAAATCCCGGTTGAGG	ZNF541	ENSG00000118156	0.40161878607304635	[307]	[860]	3	hSpCas9	negative selection	2311189
47555744	47555767	19	-	24336569	HL60	viability	GACACCCTCAACCGGGATTTGGG	ZNF541	ENSG00000118156	0.41997504452997636	[159]	[452]	4	hSpCas9	negative selection	2311190
47555751	47555774	19	-	24336569	HL60	viability	CTGCAGCGACACCCTCAACCGGG	ZNF541	ENSG00000118156	-0.8599660965814118	[921]	[1074]	-7	hSpCas9	negative selection	2311191
47555763	47555786	19	+	24336569	HL60	viability	TGTCGCTGCAGTTGAGCCCTTGG	ZNF541	ENSG00000118156	0.18959447628971926	[507]	[1225]	1	hSpCas9	negative selection	2311192
47555799	47555822	19	+	24336569	HL60	viability	AAGGGAGGTGCATTTCTGATGGG	ZNF541	ENSG00000118156	1.04378716229702	[644]	[2813]	7	hSpCas9	negative selection	2311193
47555820	47555843	19	+	24336569	HL60	viability	GGAGGGCACCCTCGTCTCCAAGG	ZNF541	ENSG00000118156	-0.32385135561992884	[332]	[562]	-3	hSpCas9	negative selection	2311194
47555828	47555851	19	-	24336569	HL60	viability	CAGTACAGCCTTGGAGACGAGGG	ZNF541	ENSG00000118156	-0.5799363479235389	[610]	[864]	-5	hSpCas9	negative selection	2311195
47555836	47555859	19	+	24336569	HL60	viability	TCCAAGGCTGTACTGGTCCATGG	ZNF541	ENSG00000118156	-1.7129508818781574	[645]	[416]	-9	hSpCas9	negative selection	2311196
47555719	47555742	19	+	24336569	KBM7	viability	ATAAAGAAAGCCTCGCGTGTTGG	ZNF541	ENSG00000118156	-0.04661688248176166	[205]	[543]	0	hSpCas9	negative selection	2378364
47555729	47555752	19	-	24336569	KBM7	viability	GATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	0.016798066223851216	[502]	[1387]	0	hSpCas9	negative selection	2378365
47555739	47555762	19	+	24336569	KBM7	viability	TGGGACCCAAATCCCGGTTGAGG	ZNF541	ENSG00000118156	0.7335512596013105	[341]	[1550]	6	hSpCas9	negative selection	2378366
47555744	47555767	19	-	24336569	KBM7	viability	GACACCCTCAACCGGGATTTGGG	ZNF541	ENSG00000118156	-0.038394423515476506	[246]	[655]	0	hSpCas9	negative selection	2378367
47555751	47555774	19	-	24336569	KBM7	viability	CTGCAGCGACACCCTCAACCGGG	ZNF541	ENSG00000118156	0.5777565869938861	[253]	[1033]	5	hSpCas9	negative selection	2378368
47555763	47555786	19	+	24336569	KBM7	viability	TGTCGCTGCAGTTGAGCCCTTGG	ZNF541	ENSG00000118156	1.1624742851351044	[379]	[2319]	8	hSpCas9	negative selection	2378369
47555799	47555822	19	+	24336569	KBM7	viability	AAGGGAGGTGCATTTCTGATGGG	ZNF541	ENSG00000118156	0.5020763992309349	[502]	[1942]	4	hSpCas9	negative selection	2378370
47555820	47555843	19	+	24336569	KBM7	viability	GGAGGGCACCCTCGTCTCCAAGG	ZNF541	ENSG00000118156	0.6823189110218535	[267]	[1172]	6	hSpCas9	negative selection	2378371
47555828	47555851	19	-	24336569	KBM7	viability	CAGTACAGCCTTGGAGACGAGGG	ZNF541	ENSG00000118156	0.2134862832580653	[559]	[1770]	2	hSpCas9	negative selection	2378372
47555836	47555859	19	+	24336569	KBM7	viability	TCCAAGGCTGTACTGGTCCATGG	ZNF541	ENSG00000118156	1.7508343618531257	[194]	[1789]	9	hSpCas9	negative selection	2378373
47524612	47524635	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGCAGAATCGCTTGAACCCAG	ZNF541	ENSG00000118156	4.376878119565056	[324,400]	[1478,1870]	9	dCas9-VP64	positive selection	2470872
47524612	47524635	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGCAGAATCGCTTGAACCCAG	ZNF541	ENSG00000118156	2.6681151119317885	[136,149]	[134,451]	9	dCas9-VP64	positive selection	2566127
47544918	47544941	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAGCGGCGAGGCATCCGCAGGG	ZNF541	ENSG00000118156	-0.3397752400924724	[2,2]	[2,0]	-5	hSpCas9	positive selection	3034777
47544831	47544854	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGATGATCACCAAGTCCCAGCGG	ZNF541	ENSG00000118156	0.5458178171988299	[3,3]	[3,5]	9	hSpCas9	positive selection	3034778
47544977	47545000	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCCTGTGCCAGAACCCCGGGG	ZNF541	ENSG00000118156	-0.12107178898512597	[3,3]	[2,2]	-2	hSpCas9	positive selection	3034779
47545385	47545408	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCCAGGCCCGGTCCACCGCGG	ZNF541	ENSG00000118156	-0.614343020156016	[2,2]	[1,1]	-7	hSpCas9	positive selection	3034780
47544918	47544941	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAGCGGCGAGGCATCCGCAGGG	ZNF541	ENSG00000118156	-0.2537827119300771	[2,2]	[2,0]	-4	hSpCas9	positive selection	3102635
47544831	47544854	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGATGATCACCAAGTCCCAGCGG	ZNF541	ENSG00000118156	-0.15362158950396948	[3,3]	[3,1]	-2	hSpCas9	positive selection	3102636
47544977	47545000	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCCTGTGCCAGAACCCCGGGG	ZNF541	ENSG00000118156	-0.10003699315838782	[3,3]	[4,0]	-1	hSpCas9	positive selection	3102637
47545385	47545408	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCCAGGCCCGGTCCACCGCGG	ZNF541	ENSG00000118156	-0.14054643454017604	[2,2]	[0,2]	-2	hSpCas9	positive selection	3102638
47549462	47549485		+	24336571	A375	resistance to PLX after 7 days	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	0.2665186725891563	[20,15]	[19,24]	7	hSpCas9	positive selection	3157741
47545884	47545907		-	24336571	A375	resistance to PLX after 7 days	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.23389885531698762	[7,6]	[7,4]	-7	hSpCas9	positive selection	3157742
47549342	47549365		+	24336571	A375	resistance to PLX after 7 days	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	-0.4056541011925924	[15,17]	[12,11]	-9	hSpCas9	positive selection	3157743
47549462	47549485		+	24336571	A375	resistance to PLX after 14 days	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	1.1709133775402687	[13,19]	[14,19]	8	hSpCas9	positive selection	3215534
47545884	47545907		-	24336571	A375	resistance to PLX after 14 days	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.20330483678561828	[6,6]	[2,1]	-2	hSpCas9	positive selection	3215535
47549342	47549365		+	24336571	A375	resistance to PLX after 14 days	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.0014072274447483601	[10,20]	[4,9]	0	hSpCas9	positive selection	3215536
47549462	47549485		+	24336571	A375	viability after 7 days	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.19825002630003663	[22]	[20,15]	-3	hSpCas9	negative selection	3273327
47545884	47545907		-	24336571	A375	viability after 7 days	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.3605131247452801	[10]	[7,6]	-5	hSpCas9	negative selection	3273328
47549342	47549365		+	24336571	A375	viability after 7 days	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.03477848173095771	[16]	[15,17]	0	hSpCas9	negative selection	3273329
47549462	47549485		+	24336571	A375	viability after 14 days	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.32818223144269226	[22]	[13,19]	-4	hSpCas9	negative selection	3331120
47545884	47545907		-	24336571	A375	viability after 14 days	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.5371681443103755	[10]	[6,6]	-6	hSpCas9	negative selection	3331121
47549342	47549365		+	24336571	A375	viability after 14 days	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.007475742115150508	[16]	[10,20]	0	hSpCas9	negative selection	3331122
47540244	47540267	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	1.399345216318263	[57,57]	[0,0]	6	hSpCas9	positive selection	3403155
47549462	47549485	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.8719568054991315	[279,279]	[0,0]	-6	hSpCas9	positive selection	3403156
47540175	47540198	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	1.1280431945008687	[69,69]	[0,0]	5	hSpCas9	positive selection	3403157
47544917	47544940	19	+	26780180	HT29	viability (Avana library 4 designs)	AGAGCGGCGAGGCATCCGCAGGG	ZNF541	ENSG00000118156	1.21816576485684	[]	[]	5	hSpCas9	negative selection	3474122
47544831	47544854	19	-	26780180	HT29	viability (Avana library 4 designs)	AGATGATCACCAAGTCCCAGCGG	ZNF541	ENSG00000118156	0.384710861844105	[]	[]	1	hSpCas9	negative selection	3474123
47544977	47545000	19	-	26780180	HT29	viability (Avana library 4 designs)	CTTCCTGTGCCAGAACCCCGGGG	ZNF541	ENSG00000118156	0.716558794422788	[]	[]	2	hSpCas9	negative selection	3474124
47545385	47545408	19	-	26780180	HT29	viability (Avana library 4 designs)	GCTCCAGGCCCGGTCCACCGCGG	ZNF541	ENSG00000118156	2.40124930614463	[]	[]	8	hSpCas9	negative selection	3474125
47544831	47544854	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGATGATCACCAAGTCCCAGCGG	ZNF541	ENSG00000118156	-1.74312297051015	[]	[]	-2	hSpCas9	negative selection	3582198
47544977	47545000	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCCTGTGCCAGAACCCCGGGG	ZNF541	ENSG00000118156	3.42492876020915	[]	[]	5	hSpCas9	negative selection	3582199
47545385	47545408	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCAGGCCCGGTCCACCGCGG	ZNF541	ENSG00000118156	7.38598466124365	[]	[]	9	hSpCas9	negative selection	3582200
47544917	47544940	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGCGGCGAGGCATCCGCAGGG	ZNF541	ENSG00000118156	5.7406768824585	[]	[]	9	hSpCas9	negative selection	3582201
47545460	47545483	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCACAGCCCCTAATTCCAGGG	ZNF541	ENSG00000118156	-4.57692444329451	[]	[]	-5	hSpCas9	negative selection	3582202
47544962	47544985	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGAGGCCGGGCTCCCCGGGG	ZNF541	ENSG00000118156	4.97776829153398	[]	[]	8	hSpCas9	negative selection	3582203
47544831	47544854	19	-	26780180	A375	viability (Avana lentiGuide)	AGATGATCACCAAGTCCCAGCGG	ZNF541	ENSG00000118156	-0.649051852330158	[]	[]	-1	hSpCas9	negative selection	3690857
47544977	47545000	19	-	26780180	A375	viability (Avana lentiGuide)	CTTCCTGTGCCAGAACCCCGGGG	ZNF541	ENSG00000118156	3.29853962629436	[]	[]	3	hSpCas9	negative selection	3690858
47545385	47545408	19	-	26780180	A375	viability (Avana lentiGuide)	GCTCCAGGCCCGGTCCACCGCGG	ZNF541	ENSG00000118156	14.2001070676183	[]	[]	8	hSpCas9	negative selection	3690859
47544917	47544940	19	+	26780180	A375	viability (Avana lentiGuide)	AGAGCGGCGAGGCATCCGCAGGG	ZNF541	ENSG00000118156	1.3022744781448	[]	[]	1	hSpCas9	negative selection	3690860
47545460	47545483	19	-	26780180	A375	viability (Avana lentiGuide)	GTTCACAGCCCCTAATTCCAGGG	ZNF541	ENSG00000118156	1.5049340406387	[]	[]	1	hSpCas9	negative selection	3690861
47544962	47544985	19	+	26780180	A375	viability (Avana lentiGuide)	CCTGGAGGCCGGGCTCCCCGGGG	ZNF541	ENSG00000118156	5.82016303778864	[]	[]	5	hSpCas9	negative selection	3690862
47544831	47544854	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATGATCACCAAGTCCCAGCGG	ZNF541	ENSG00000118156	0.061852568198453126	[4]	[4,5]	1	hSpCas9	positive selection	3799464
47544977	47545000	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCCTGTGCCAGAACCCCGGGG	ZNF541	ENSG00000118156	0.1224478926313273	[4]	[5,4]	3	hSpCas9	positive selection	3799465
47545385	47545408	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCAGGCCCGGTCCACCGCGG	ZNF541	ENSG00000118156	0.4237813336528555	[3]	[5,4]	9	hSpCas9	positive selection	3799466
47544917	47544940	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGCGGCGAGGCATCCGCAGGG	ZNF541	ENSG00000118156	0.15118457739778793	[4]	[4,4]	4	hSpCas9	positive selection	3799467
47545460	47545483	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCACAGCCCCTAATTCCAGGG	ZNF541	ENSG00000118156	-0.040671998351271055	[5]	[5,5]	0	hSpCas9	positive selection	3799468
47544962	47544985	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGAGGCCGGGCTCCCCGGGG	ZNF541	ENSG00000118156	0.35914086327171635	[4]	[5,5]	9	hSpCas9	positive selection	3799469
47544831	47544854	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATGATCACCAAGTCCCAGCGG	ZNF541	ENSG00000118156	0.055153056455315104	[5]	[5,3]	1	hSpCas9	positive selection	3908071
47544977	47545000	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCCTGTGCCAGAACCCCGGGG	ZNF541	ENSG00000118156	-0.17094535375264427	[5]	[3,4]	-2	hSpCas9	positive selection	3908072
47545385	47545408	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCAGGCCCGGTCCACCGCGG	ZNF541	ENSG00000118156	-0.9382293743758715	[4]	[1,1]	-8	hSpCas9	positive selection	3908073
47544917	47544940	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGCGGCGAGGCATCCGCAGGG	ZNF541	ENSG00000118156	-0.3132333797292461	[4]	[1,3]	-4	hSpCas9	positive selection	3908074
47545460	47545483	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCACAGCCCCTAATTCCAGGG	ZNF541	ENSG00000118156	0.2546547751103629	[6]	[7,6]	6	hSpCas9	positive selection	3908075
47544962	47544985	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGAGGCCGGGCTCCCCGGGG	ZNF541	ENSG00000118156	0.2556298608395971	[4]	[5,4]	6	hSpCas9	positive selection	3908076
47549462	47549485	19	+	26780180	A375	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	1.9892901722533	[]	[]	9	hSpCas9	negative selection	4016154
47540244	47540267	19	+	26780180	A375	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	1.57173311053078	[]	[]	8	hSpCas9	negative selection	4016155
47545884	47545907	19	-	26780180	A375	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	2.05873621011276	[]	[]	9	hSpCas9	negative selection	4016156
47545679	47545702	19	+	26780180	A375	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	1.58213294313567	[]	[]	8	hSpCas9	negative selection	4016157
47540175	47540198	19	-	26780180	A375	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	1.22806772896252	[]	[]	6	hSpCas9	negative selection	4016158
47549342	47549365	19	+	26780180	A375	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	1.45472715631277	[]	[]	8	hSpCas9	negative selection	4016159
47549462	47549485	19	+	26780180	HT29	viability (GeCKOv2 library)	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	1.45578818694942	[]	[]	7	hSpCas9	negative selection	4124120
47540244	47540267	19	+	26780180	HT29	viability (GeCKOv2 library)	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	0.964839564345144	[]	[]	4	hSpCas9	negative selection	4124121
47545884	47545907	19	-	26780180	HT29	viability (GeCKOv2 library)	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	2.17388048009167	[]	[]	9	hSpCas9	negative selection	4124122
47545679	47545702	19	+	26780180	HT29	viability (GeCKOv2 library)	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	1.41836007005191	[]	[]	7	hSpCas9	negative selection	4124123
47540175	47540198	19	-	26780180	HT29	viability (GeCKOv2 library)	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	1.45698014968654	[]	[]	7	hSpCas9	negative selection	4124124
47549342	47549365	19	+	26780180	HT29	viability (GeCKOv2 library)	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.90805362116892	[]	[]	4	hSpCas9	negative selection	4124125
47549462	47549485	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	0.36883456755137933	[3]	[3,4]	8	hSpCas9	positive selection	4184857
47545884	47545907	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	0.29367060511362597	[2]	[3,0]	7	hSpCas9	positive selection	4184858
47549342	47549365	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	-0.018503723701290636	[4]	[2,2]	0	hSpCas9	positive selection	4184859
47549462	47549485	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	0.597035904100484	[4]	[0,0,1,3]	4	hSpCas9	positive selection	4248879
47545884	47545907	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.346257083518836	[2]	[0,0,0,0]	-5	hSpCas9	positive selection	4248880
47549342	47549365	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	-0.21920080541299017	[4]	[2,2,1,0]	-3	hSpCas9	positive selection	4248881
47545884	47545907	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	0.004519821456759665	[3]	[1,2]	0	hSpCas9	positive selection	4309805
47545679	47545702	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.25738397836562116	[3]	[3,1]	-5	hSpCas9	positive selection	4309806
47549342	47549365	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.13256541111174852	[4]	[4,3]	2	hSpCas9	positive selection	4309807
47540244	47540267	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	0.02848916068095053	[2]	[2,0]	0	hSpCas9	positive selection	4374053
47549462	47549485	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.5474880229692658	[3]	[3,0]	-8	hSpCas9	positive selection	4374054
47540175	47540198	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.3305797244380447	[2]	[1,0]	-6	hSpCas9	positive selection	4374055
47544547	47544569	19	+	27760321	OCIAML3	viability	GCAAGGGGCGTTGGAACCGCGG	ZNF541	ENSG00000118156	-0.13780622451803887	[630,548]	[410,427]	-1	hSpCas9	negative selection	4457134
47544583	47544605	19	-	27760321	OCIAML3	viability	GCACGAGACGAGACGCAAAGGG	ZNF541	ENSG00000118156	0.41833020420699224	[588,478]	[536,578]	5	hSpCas9	negative selection	4457135
47545680	47545702	19	+	27760321	OCIAML3	viability	GACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.40016577391584346	[523,480]	[239,372]	-4	hSpCas9	negative selection	4457136
47545925	47545947	19	-	27760321	OCIAML3	viability	CCCTTCGTGTGCATCGAGCAGG	ZNF541	ENSG00000118156	-0.25371299299839534	[877,750]	[427,668]	-3	hSpCas9	negative selection	4457137
47555729	47555751	19	-	27760321	OCIAML3	viability	ATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	0.47903139084185276	[794,660]	[550,1101]	6	hSpCas9	negative selection	4457138
47544547	47544569	19	+	27760321	OCIAML2	viability	GCAAGGGGCGTTGGAACCGCGG	ZNF541	ENSG00000118156	0.05447911357285101	[630,548]	[427,581]	0	hSpCas9	negative selection	4540597
47544583	47544605	19	-	27760321	OCIAML2	viability	GCACGAGACGAGACGCAAAGGG	ZNF541	ENSG00000118156	-0.5712771181607899	[588,478]	[296,278]	-6	hSpCas9	negative selection	4540598
47545680	47545702	19	+	27760321	OCIAML2	viability	GACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.21341430206310463	[523,480]	[252,478]	-3	hSpCas9	negative selection	4540599
47545925	47545947	19	-	27760321	OCIAML2	viability	CCCTTCGTGTGCATCGAGCAGG	ZNF541	ENSG00000118156	0.01520131979068473	[877,750]	[608,735]	0	hSpCas9	negative selection	4540600
47555729	47555751	19	-	27760321	OCIAML2	viability	ATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	-0.06076411524682268	[794,660]	[487,659]	-1	hSpCas9	negative selection	4540601
47544547	47544569	19	+	27760321	MV411	viability	GCAAGGGGCGTTGGAACCGCGG	ZNF541	ENSG00000118156	0.002026818337045877	[630,548]	[322,487]	0	hSpCas9	negative selection	4624060
47544583	47544605	19	-	27760321	MV411	viability	GCACGAGACGAGACGCAAAGGG	ZNF541	ENSG00000118156	-0.4188374867924107	[588,478]	[59,565]	-3	hSpCas9	negative selection	4624061
47545680	47545702	19	+	27760321	MV411	viability	GACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-1.66692994521893	[523,480]	[109,95]	-8	hSpCas9	negative selection	4624062
47545925	47545947	19	-	27760321	MV411	viability	CCCTTCGTGTGCATCGAGCAGG	ZNF541	ENSG00000118156	0.6857954567044825	[877,750]	[506,1394]	5	hSpCas9	negative selection	4624063
47555729	47555751	19	-	27760321	MV411	viability	ATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	0.3378370194044563	[794,660]	[333,1010]	2	hSpCas9	negative selection	4624064
47544547	47544569	19	+	27760321	HL60	viability	GCAAGGGGCGTTGGAACCGCGG	ZNF541	ENSG00000118156	-0.6640422123214476	[630,548]	[267,340]	-6	hSpCas9	negative selection	4707523
47544583	47544605	19	-	27760321	HL60	viability	GCACGAGACGAGACGCAAAGGG	ZNF541	ENSG00000118156	-0.42113008688254394	[588,478]	[260,390]	-5	hSpCas9	negative selection	4707524
47545680	47545702	19	+	27760321	HL60	viability	GACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.5255158283809458	[523,480]	[188,386]	-5	hSpCas9	negative selection	4707525
47545925	47545947	19	-	27760321	HL60	viability	CCCTTCGTGTGCATCGAGCAGG	ZNF541	ENSG00000118156	-0.21426476945335327	[877,750]	[595,545]	-2	hSpCas9	negative selection	4707526
47555729	47555751	19	-	27760321	HL60	viability	ATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	0.8883249812201516	[794,660]	[932,1268]	8	hSpCas9	negative selection	4707527
47544547	47544569	19	+	27760321	HT1080	viability	GCAAGGGGCGTTGGAACCGCGG	ZNF541	ENSG00000118156	0.7785487656712042	[548,428]	[274,398]	4	hSpCas9	negative selection	4790986
47544583	47544605	19	-	27760321	HT1080	viability	GCACGAGACGAGACGCAAAGGG	ZNF541	ENSG00000118156	-0.3050971812355618	[478,373]	[137,136]	-1	hSpCas9	negative selection	4790987
47545680	47545702	19	+	27760321	HT1080	viability	GACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	1.06364206942809	[480,375]	[247,475]	6	hSpCas9	negative selection	4790988
47545925	47545947	19	-	27760321	HT1080	viability	CCCTTCGTGTGCATCGAGCAGG	ZNF541	ENSG00000118156	2.1963938342786826	[750,585]	[2159,191]	9	hSpCas9	negative selection	4790989
47555729	47555751	19	-	27760321	HT1080	viability	ATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	0.7666018855813084	[660,515]	[205,609]	4	hSpCas9	negative selection	4790990
47544547	47544569	19	+	27760321	HT29	viability after 7 days	GCAAGGGGCGTTGGAACCGCGG	ZNF541	ENSG00000118156	0.2707505086156384	[548,428]	[977,954,384]	4	hSpCas9	negative selection	4874449
47544583	47544605	19	-	27760321	HT29	viability after 7 days	GCACGAGACGAGACGCAAAGGG	ZNF541	ENSG00000118156	0.49905118046291674	[478,373]	[846,611,871]	7	hSpCas9	negative selection	4874450
47545680	47545702	19	+	27760321	HT29	viability after 7 days	GACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.16388144155817697	[480,375]	[766,511,593]	2	hSpCas9	negative selection	4874451
47545925	47545947	19	-	27760321	HT29	viability after 7 days	CCCTTCGTGTGCATCGAGCAGG	ZNF541	ENSG00000118156	0.170017014323258	[750,585]	[754,1136,976]	2	hSpCas9	negative selection	4874452
47555729	47555751	19	-	27760321	HT29	viability after 7 days	ATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	-0.2767373608910234	[660,515]	[784,526,584]	-4	hSpCas9	negative selection	4874453
47544547	47544569	19	+	27760321	HT29	viability after 25 days	GCAAGGGGCGTTGGAACCGCGG	ZNF541	ENSG00000118156	0.27895147832154527	[548,428]	[703,611,719]	3	hSpCas9	negative selection	4957912
47544583	47544605	19	-	27760321	HT29	viability after 25 days	GCACGAGACGAGACGCAAAGGG	ZNF541	ENSG00000118156	0.02652953047180706	[478,373]	[496,379,624]	0	hSpCas9	negative selection	4957913
47545680	47545702	19	+	27760321	HT29	viability after 25 days	GACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.007519332475599744	[480,375]	[419,463,591]	0	hSpCas9	negative selection	4957914
47545925	47545947	19	-	27760321	HT29	viability after 25 days	CCCTTCGTGTGCATCGAGCAGG	ZNF541	ENSG00000118156	-0.2207540862236741	[750,585]	[458,717,817]	-2	hSpCas9	negative selection	4957915
47555729	47555751	19	-	27760321	HT29	viability after 25 days	ATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	-0.08764035604808995	[660,515]	[446,609,877]	-1	hSpCas9	negative selection	4957916
47544547	47544569	19	+	27760321	HT29	viability after 22 days	GCAAGGGGCGTTGGAACCGCGG	ZNF541	ENSG00000118156	0.4028992794586151	[548,428]	[1005,527,700]	4	hSpCas9	negative selection	5041375
47544583	47544605	19	-	27760321	HT29	viability after 22 days	GCACGAGACGAGACGCAAAGGG	ZNF541	ENSG00000118156	0.09905185791359089	[478,373]	[616,426,537]	1	hSpCas9	negative selection	5041376
47545680	47545702	19	+	27760321	HT29	viability after 22 days	GACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.07369102448553055	[480,375]	[555,399,607]	0	hSpCas9	negative selection	5041377
47545925	47545947	19	-	27760321	HT29	viability after 22 days	CCCTTCGTGTGCATCGAGCAGG	ZNF541	ENSG00000118156	0.2605466715616771	[750,585]	[1045,909,816]	2	hSpCas9	negative selection	5041378
47555729	47555751	19	-	27760321	HT29	viability after 22 days	ATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	0.04663896068518825	[660,515]	[495,773,844]	0	hSpCas9	negative selection	5041379
47544547	47544569	19	+	27760321	HT29	viability after 19 days	GCAAGGGGCGTTGGAACCGCGG	ZNF541	ENSG00000118156	-0.06579654852956962	[548,428]	[598,435,572]	0	hSpCas9	negative selection	5124838
47544583	47544605	19	-	27760321	HT29	viability after 19 days	GCACGAGACGAGACGCAAAGGG	ZNF541	ENSG00000118156	0.02527901548217243	[478,373]	[422,287,759]	0	hSpCas9	negative selection	5124839
47545680	47545702	19	+	27760321	HT29	viability after 19 days	GACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.15437936685320508	[480,375]	[603,541,497]	1	hSpCas9	negative selection	5124840
47545925	47545947	19	-	27760321	HT29	viability after 19 days	CCCTTCGTGTGCATCGAGCAGG	ZNF541	ENSG00000118156	-0.3198083767987806	[750,585]	[777,691,392]	-3	hSpCas9	negative selection	5124841
47555729	47555751	19	-	27760321	HT29	viability after 19 days	ATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	-0.12009392746494729	[660,515]	[766,487,617]	-1	hSpCas9	negative selection	5124842
47544547	47544569	19	+	27760321	HT29	viability after 16 days	GCAAGGGGCGTTGGAACCGCGG	ZNF541	ENSG00000118156	0.44330907076085696	[548,428]	[565,970,671]	5	hSpCas9	negative selection	5208301
47544583	47544605	19	-	27760321	HT29	viability after 16 days	GCACGAGACGAGACGCAAAGGG	ZNF541	ENSG00000118156	0.23460947033674318	[478,373]	[527,564,587]	2	hSpCas9	negative selection	5208302
47545680	47545702	19	+	27760321	HT29	viability after 16 days	GACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.6215861551762758	[480,375]	[547,736,909]	7	hSpCas9	negative selection	5208303
47545925	47545947	19	-	27760321	HT29	viability after 16 days	CCCTTCGTGTGCATCGAGCAGG	ZNF541	ENSG00000118156	0.14897367442529563	[750,585]	[916,980,593]	1	hSpCas9	negative selection	5208304
47555729	47555751	19	-	27760321	HT29	viability after 16 days	ATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	0.019232205553612047	[660,515]	[865,607,547]	0	hSpCas9	negative selection	5208305
47544547	47544569	19	+	27760321	HT29	viability after 13 days	GCAAGGGGCGTTGGAACCGCGG	ZNF541	ENSG00000118156	0.16300843862959663	[548,428]	[756,611,541]	2	hSpCas9	negative selection	5291764
47544583	47544605	19	-	27760321	HT29	viability after 13 days	GCACGAGACGAGACGCAAAGGG	ZNF541	ENSG00000118156	0.5804041700968158	[478,373]	[912,633,675]	7	hSpCas9	negative selection	5291765
47545680	47545702	19	+	27760321	HT29	viability after 13 days	GACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.2261811044410193	[480,375]	[380,501,393]	-3	hSpCas9	negative selection	5291766
47545925	47545947	19	-	27760321	HT29	viability after 13 days	CCCTTCGTGTGCATCGAGCAGG	ZNF541	ENSG00000118156	-0.38288230531294853	[750,585]	[723,484,575]	-4	hSpCas9	negative selection	5291767
47555729	47555751	19	-	27760321	HT29	viability after 13 days	ATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	0.14878408766666462	[660,515]	[1018,460,787]	1	hSpCas9	negative selection	5291768
47544547	47544569	19	+	27760321	HT29	viability after 10 days	GCAAGGGGCGTTGGAACCGCGG	ZNF541	ENSG00000118156	0.2576706309498537	[548,428]	[746,965,488]	3	hSpCas9	negative selection	5375227
47544583	47544605	19	-	27760321	HT29	viability after 10 days	GCACGAGACGAGACGCAAAGGG	ZNF541	ENSG00000118156	0.512517934264311	[478,373]	[903,797,581]	7	hSpCas9	negative selection	5375228
47545680	47545702	19	+	27760321	HT29	viability after 10 days	GACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.1470074299674501	[480,375]	[532,733,515]	2	hSpCas9	negative selection	5375229
47545925	47545947	19	-	27760321	HT29	viability after 10 days	CCCTTCGTGTGCATCGAGCAGG	ZNF541	ENSG00000118156	0.07978548983300582	[750,585]	[1082,908,659]	1	hSpCas9	negative selection	5375230
47555729	47555751	19	-	27760321	HT29	viability after 10 days	ATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	0.017942557940539672	[660,515]	[755,621,847]	0	hSpCas9	negative selection	5375231
47544547	47544569	19	+	27760321	MOLM13	viability	GCAAGGGGCGTTGGAACCGCGG	ZNF541	ENSG00000118156	0.34822184251948024	[630,548]	[755,138]	2	hSpCas9	negative selection	5458690
47544583	47544605	19	-	27760321	MOLM13	viability	GCACGAGACGAGACGCAAAGGG	ZNF541	ENSG00000118156	-0.27882114185486256	[588,478]	[10,447]	-2	hSpCas9	negative selection	5458691
47545680	47545702	19	+	27760321	MOLM13	viability	GACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.2637934922567196	[523,480]	[39,402]	-2	hSpCas9	negative selection	5458692
47545925	47545947	19	-	27760321	MOLM13	viability	CCCTTCGTGTGCATCGAGCAGG	ZNF541	ENSG00000118156	-0.6803815965894251	[877,750]	[159,392]	-4	hSpCas9	negative selection	5458693
47555729	47555751	19	-	27760321	MOLM13	viability	ATTTGGGTCCCAACACGCGAGG	ZNF541	ENSG00000118156	0.5037845515753713	[794,660]	[634,532]	3	hSpCas9	negative selection	5458694
47545884	47545907	19	-	27260156	BXPC3	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.49444347145003237	[686]	[424,510,532,585]	-8	hSpCas9	negative selection	5582265
47545679	47545702	19	+	27260156	BXPC3	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.2745517401900949	[807]	[697,733,694,653]	-6	hSpCas9	negative selection	5582266
47549342	47549365	19	+	27260156	BXPC3	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.09092708174972652	[1174]	[1204,1272,1318,1459]	2	hSpCas9	negative selection	5582267
47540244	47540267	19	+	27260156	BXPC3	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.3569071001489039	[216]	[106,149,157,318]	-7	hSpCas9	negative selection	5646513
47549462	47549485	19	+	27260156	BXPC3	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.22669910352533995	[762]	[644,625,747,715]	-5	hSpCas9	negative selection	5646514
47540175	47540198	19	-	27260156	BXPC3	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	0.03943510665909433	[201]	[251,194,181,236]	0	hSpCas9	negative selection	5646515
47545884	47545907	19	-	27260156	A673	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.36544865672237525	[686]	[661,721,496,682]	-7	hSpCas9	negative selection	5703516
47545679	47545702	19	+	27260156	A673	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.016462665891705308	[807]	[1038,948,690,1179]	0	hSpCas9	negative selection	5703517
47549342	47549365	19	+	27260156	A673	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.3160526689870209	[1174]	[1972,1627,1620,1833]	7	hSpCas9	negative selection	5703518
47540244	47540267	19	+	27260156	A673	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.1285204983796373	[216]	[209,263,221,253]	-3	hSpCas9	negative selection	5767764
47549462	47549485	19	+	27260156	A673	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.2984545008484052	[762]	[948,738,622,688]	-6	hSpCas9	negative selection	5767765
47540175	47540198	19	-	27260156	A673	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	0.047674247105034206	[201]	[243,281,266,204]	1	hSpCas9	negative selection	5767766
47545884	47545907	19	-	27260156	A375	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.33576431131471984	[686]	[540,586,757,645]	-5	hSpCas9	negative selection	5824767
47545679	47545702	19	+	27260156	A375	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.2596296532213357	[807]	[660,968,752,790]	-4	hSpCas9	negative selection	5824768
47549342	47549365	19	+	27260156	A375	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	-0.011545412995339177	[1174]	[1468,1310,1345,1313]	0	hSpCas9	negative selection	5824769
47540244	47540267	19	+	27260156	A375	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	0.0020902649043883503	[216]	[280,383,172,200]	0	hSpCas9	negative selection	5889015
47549462	47549485	19	+	27260156	A375	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.08979341013119291	[762]	[923,946,845,665]	-1	hSpCas9	negative selection	5889016
47540175	47540198	19	-	27260156	A375	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	0.11900251178554466	[201]	[285,179,221,317]	1	hSpCas9	negative selection	5889017
47545884	47545907	19	-	27260156	COLO741	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.40708110600335534	[686]	[763,665,569]	-7	hSpCas9	negative selection	5946018
47545679	47545702	19	+	27260156	COLO741	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.027996728240256785	[807]	[1140,822,1076]	0	hSpCas9	negative selection	5946019
47549342	47549365	19	+	27260156	COLO741	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.08638364923812758	[1174]	[1905,1567,1348]	1	hSpCas9	negative selection	5946020
47540244	47540267	19	+	27260156	COLO741	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	0.03354463479201497	[216]	[462,166,238]	0	hSpCas9	negative selection	6010266
47549462	47549485	19	+	27260156	COLO741	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.3912135701162931	[762]	[873,535,822]	-7	hSpCas9	negative selection	6010267
47540175	47540198	19	-	27260156	COLO741	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	0.18263978754719257	[201]	[342,158,373]	4	hSpCas9	negative selection	6010268
47545884	47545907	19	-	27260156	CAL120	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.4081304906597438	[686]	[642,628,659]	-5	hSpCas9	negative selection	6067269
47545679	47545702	19	+	27260156	CAL120	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.0057207164770892716	[807]	[1184,950,919]	0	hSpCas9	negative selection	6067270
47549342	47549365	19	+	27260156	CAL120	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.46656154901233715	[1174]	[2148,1866,2062]	7	hSpCas9	negative selection	6067271
47540244	47540267	19	+	27260156	CAL120	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	0.27043773220327416	[216]	[220,289,447]	4	hSpCas9	negative selection	6131517
47549462	47549485	19	+	27260156	CAL120	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.4405914662225077	[762]	[559,733,781]	-6	hSpCas9	negative selection	6131518
47540175	47540198	19	-	27260156	CAL120	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	0.2872450616671264	[201]	[464,120,356]	4	hSpCas9	negative selection	6131519
47545884	47545907	19	-	27260156	CADOES1	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.6398845877627336	[686]	[333,285,510,512]	-8	hSpCas9	negative selection	6188520
47545679	47545702	19	+	27260156	CADOES1	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.09270049694679339	[807]	[709,619,749,739]	-1	hSpCas9	negative selection	6188521
47549342	47549365	19	+	27260156	CADOES1	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.33236189825226803	[1174]	[1375,1617,1345,1155]	5	hSpCas9	negative selection	6188522
47540244	47540267	19	+	27260156	CADOES1	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.16994830385436144	[216]	[111,178,316,106]	-3	hSpCas9	negative selection	6252768
47549462	47549485	19	+	27260156	CADOES1	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.4294363337029771	[762]	[497,292,541,783]	-6	hSpCas9	negative selection	6252769
47540175	47540198	19	-	27260156	CADOES1	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.2734544767755813	[201]	[97,194,95,235]	-5	hSpCas9	negative selection	6252770
47545884	47545907	19	-	27260156	EWS502	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.44422086854021314	[686]	[373,521,550,723]	-6	hSpCas9	negative selection	6309771
47545679	47545702	19	+	27260156	EWS502	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.11038129655455675	[807]	[873,603,740,957]	-2	hSpCas9	negative selection	6309772
47549342	47549365	19	+	27260156	EWS502	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.1804469002057152	[1174]	[1133,1512,1466,1562]	3	hSpCas9	negative selection	6309773
47540244	47540267	19	+	27260156	EWS502	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.35493315587371854	[216]	[175,173,220,145]	-6	hSpCas9	negative selection	6374019
47549462	47549485	19	+	27260156	EWS502	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.43756115850239125	[762]	[566,472,621,741]	-6	hSpCas9	negative selection	6374020
47540175	47540198	19	-	27260156	EWS502	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.381750614177798	[201]	[128,155,219,155]	-6	hSpCas9	negative selection	6374021
47545884	47545907	19	-	27260156	EW8	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.3517331213744338	[686]	[344,437,223,761]	-6	hSpCas9	negative selection	6431022
47545679	47545702	19	+	27260156	EW8	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.06874632788647961	[807]	[754,706,443,634]	-1	hSpCas9	negative selection	6431023
47549342	47549365	19	+	27260156	EW8	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.2880500818771867	[1174]	[1154,1804,852,889]	5	hSpCas9	negative selection	6431024
47540244	47540267	19	+	27260156	EW8	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.26277982160862057	[216]	[239,100,98,163]	-5	hSpCas9	negative selection	6495270
47549462	47549485	19	+	27260156	EW8	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.3412177081900025	[762]	[565,468,353,592]	-6	hSpCas9	negative selection	6495271
47540175	47540198	19	-	27260156	EW8	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.11483241545541811	[201]	[139,188,182,85]	-2	hSpCas9	negative selection	6495272
47545884	47545907	19	-	27260156	CORL105	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.5852812460232226	[686]	[632,552,582,385]	-8	hSpCas9	negative selection	6552273
47545679	47545702	19	+	27260156	CORL105	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.04855235745853259	[807]	[1093,840,1044,706]	-1	hSpCas9	negative selection	6552274
47549342	47549365	19	+	27260156	CORL105	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.0801815601970024	[1174]	[1399,1654,1566,1206]	1	hSpCas9	negative selection	6552275
47540244	47540267	19	+	27260156	CORL105	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.42192479542652084	[216]	[152,162,261,190]	-6	hSpCas9	negative selection	6616521
47549462	47549485	19	+	27260156	CORL105	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.5852891696334657	[762]	[690,523,782,417]	-8	hSpCas9	negative selection	6616522
47540175	47540198	19	-	27260156	CORL105	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.3473412745231452	[201]	[220,168,222,137]	-6	hSpCas9	negative selection	6616523
47545884	47545907	19	-	27260156	HS294T	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.4636724684984776	[686]	[173,125,150,348]	-6	hSpCas9	negative selection	6673524
47545679	47545702	19	+	27260156	HS294T	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.1951319257191978	[807]	[348,352,407,312]	2	hSpCas9	negative selection	6673525
47549342	47549365	19	+	27260156	HS294T	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.23063466366497254	[1174]	[469,415,564,720]	3	hSpCas9	negative selection	6673526
47540244	47540267	19	+	27260156	HS294T	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.5589579466035357	[216]	[51,35,87,51]	-7	hSpCas9	negative selection	6737772
47549462	47549485	19	+	27260156	HS294T	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.5940884858088848	[762]	[173,154,212,251]	-7	hSpCas9	negative selection	6737773
47540175	47540198	19	-	27260156	HS294T	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.14810990211073527	[201]	[68,77,51,84]	-2	hSpCas9	negative selection	6737774
47545884	47545907	19	-	27260156	HCC44	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.3000314181730328	[686]	[414,546,790,780]	-5	hSpCas9	negative selection	6794775
47545679	47545702	19	+	27260156	HCC44	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.05783785402231645	[807]	[1239,541,1244,906]	0	hSpCas9	negative selection	6794776
47549342	47549365	19	+	27260156	HCC44	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.5344918416755791	[1174]	[1914,1410,2440,2072]	8	hSpCas9	negative selection	6794777
47540244	47540267	19	+	27260156	HCC44	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	0.4844211072282688	[216]	[254,226,386,511]	7	hSpCas9	negative selection	6859023
47549462	47549485	19	+	27260156	HCC44	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	0.13962699459336647	[762]	[1214,404,1032,1247]	2	hSpCas9	negative selection	6859024
47540175	47540198	19	-	27260156	HCC44	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	0.04868929868962257	[201]	[162,183,436,195]	0	hSpCas9	negative selection	6859025
47545884	47545907	19	-	27260156	G402	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.23368286048161913	[686]	[742,797,832,494]	-3	hSpCas9	negative selection	6916026
47545679	47545702	19	+	27260156	G402	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.18183637878797398	[807]	[790,853,1028,790]	-2	hSpCas9	negative selection	6916027
47549342	47549365	19	+	27260156	G402	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.10941865514669158	[1174]	[1613,1560,1228,1775]	1	hSpCas9	negative selection	6916028
47540244	47540267	19	+	27260156	G402	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	0.6212768539864184	[216]	[428,463,353,387]	7	hSpCas9	negative selection	6980274
47549462	47549485	19	+	27260156	G402	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.5613389393300726	[762]	[450,714,784,552]	-6	hSpCas9	negative selection	6980275
47540175	47540198	19	-	27260156	G402	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	1.018476223249138	[201]	[359,368,280,935]	9	hSpCas9	negative selection	6980276
47545884	47545907	19	-	27260156	L33	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.3638277945160855	[686]	[353,271,349,564]	-7	hSpCas9	negative selection	7037277
47545679	47545702	19	+	27260156	L33	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.01164875597066084	[807]	[749,363,523,787]	0	hSpCas9	negative selection	7037278
47549342	47549365	19	+	27260156	L33	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.3520095427120411	[1174]	[1564,534,1019,1503]	7	hSpCas9	negative selection	7037279
47540244	47540267	19	+	27260156	L33	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.25667246925028264	[216]	[206,52,97,232]	-5	hSpCas9	negative selection	7101525
47549462	47549485	19	+	27260156	L33	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.28999108643863947	[762]	[636,264,322,696]	-6	hSpCas9	negative selection	7101526
47540175	47540198	19	-	27260156	L33	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.03513604721244379	[201]	[189,69,127,223]	-1	hSpCas9	negative selection	7101527
47545884	47545907	19	-	27260156	K562	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.6131256545638448	[686]	[463,496,326,323]	-6	hSpCas9	negative selection	7158528
47545679	47545702	19	+	27260156	K562	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.07835355213143091	[807]	[1003,904,379,485]	-1	hSpCas9	negative selection	7158529
47549342	47549365	19	+	27260156	K562	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	-0.27091827535299307	[1174]	[1014,814,816,820]	-3	hSpCas9	negative selection	7158530
47540244	47540267	19	+	27260156	K562	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.3144565007821336	[216]	[270,210,29,122]	-4	hSpCas9	negative selection	7222776
47549462	47549485	19	+	27260156	K562	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.024759962799045465	[762]	[557,471,458,1099]	0	hSpCas9	negative selection	7222777
47540175	47540198	19	-	27260156	K562	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.49171108421236265	[201]	[35,188,56,212]	-5	hSpCas9	negative selection	7222778
47545884	47545907	19	-	27260156	HT29	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.629404919397655	[686]	[515,617,545,486]	-8	hSpCas9	negative selection	7279779
47545679	47545702	19	+	27260156	HT29	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.11816822454090004	[807]	[922,1059,874,784]	-2	hSpCas9	negative selection	7279780
47549342	47549365	19	+	27260156	HT29	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.1007927429841533	[1174]	[1505,1686,1581,1371]	2	hSpCas9	negative selection	7279781
47540244	47540267	19	+	27260156	HT29	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	0.11536177885171384	[216]	[306,418,303,141]	2	hSpCas9	negative selection	7344027
47549462	47549485	19	+	27260156	HT29	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.15264763766241907	[762]	[971,973,761,666]	-3	hSpCas9	negative selection	7344028
47540175	47540198	19	-	27260156	HT29	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.08220222658335685	[201]	[202,283,259,186]	-2	hSpCas9	negative selection	7344029
47545884	47545907	19	-	27260156	MHHES1	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.39124982376481005	[686]	[661,666,722,364]	-6	hSpCas9	negative selection	7401030
47545679	47545702	19	+	27260156	MHHES1	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.22824226897055067	[807]	[842,787,786,698]	-4	hSpCas9	negative selection	7401031
47549342	47549365	19	+	27260156	MHHES1	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.2123410370859924	[1174]	[1468,1948,1445,1317]	4	hSpCas9	negative selection	7401032
47540244	47540267	19	+	27260156	MHHES1	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	0.5479303063169156	[216]	[400,320,502,228]	8	hSpCas9	negative selection	7465278
47549462	47549485	19	+	27260156	MHHES1	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.31281631037004537	[762]	[948,825,622,453]	-5	hSpCas9	negative selection	7465279
47540175	47540198	19	-	27260156	MHHES1	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.27079439561768637	[201]	[303,243,135,104]	-5	hSpCas9	negative selection	7465280
47545884	47545907	19	-	27260156	MEWO	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.45344757856228124	[686]	[435,382,582]	-7	hSpCas9	negative selection	7522281
47545679	47545702	19	+	27260156	MEWO	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.05826134627250301	[807]	[711,691,942]	1	hSpCas9	negative selection	7522282
47549342	47549365	19	+	27260156	MEWO	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.17863190461068568	[1174]	[1261,1186,1286]	4	hSpCas9	negative selection	7522283
47540244	47540267	19	+	27260156	MEWO	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.08049534091460742	[216]	[283,146,162]	-2	hSpCas9	negative selection	7586529
47549462	47549485	19	+	27260156	MEWO	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.2295221728042231	[762]	[642,609,579]	-5	hSpCas9	negative selection	7586530
47540175	47540198	19	-	27260156	MEWO	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.04015786794570486	[201]	[126,253,158]	-1	hSpCas9	negative selection	7586531
47545884	47545907	19	-	27260156	LNCAPCLONEFGC	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.3451774885757827	[686]	[497,384,556,535]	-5	hSpCas9	negative selection	7643532
47545679	47545702	19	+	27260156	LNCAPCLONEFGC	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.3016721087174443	[807]	[698,1034,1028,858]	5	hSpCas9	negative selection	7643533
47549342	47549365	19	+	27260156	LNCAPCLONEFGC	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.3422026674253238	[1174]	[1336,1356,1274,1415]	5	hSpCas9	negative selection	7643534
47540244	47540267	19	+	27260156	LNCAPCLONEFGC	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	0.042217494822048396	[216]	[285,169,262,99]	0	hSpCas9	negative selection	7707780
47549462	47549485	19	+	27260156	LNCAPCLONEFGC	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.11214899728753147	[762]	[589,565,677,734]	-2	hSpCas9	negative selection	7707781
47540175	47540198	19	-	27260156	LNCAPCLONEFGC	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	0.01717469506954883	[201]	[132,233,202,170]	0	hSpCas9	negative selection	7707782
47545884	47545907	19	-	27260156	PANC0327	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.6705273615374236	[686]	[410,513,352,240]	-7	hSpCas9	negative selection	7764783
47545679	47545702	19	+	27260156	PANC0327	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.01451845142013275	[807]	[604,679,1026,525]	0	hSpCas9	negative selection	7764784
47549342	47549365	19	+	27260156	PANC0327	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.5985975546469007	[1174]	[2330,1479,1385,1198]	8	hSpCas9	negative selection	7764785
47540244	47540267	19	+	27260156	PANC0327	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.747552656151687	[216]	[92,118,167,76]	-7	hSpCas9	negative selection	7829031
47549462	47549485	19	+	27260156	PANC0327	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.2200847144773071	[762]	[634,662,439,582]	-3	hSpCas9	negative selection	7829032
47540175	47540198	19	-	27260156	PANC0327	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	0.4895673274667154	[201]	[98,127,277,505]	7	hSpCas9	negative selection	7829033
47545884	47545907	19	-	27260156	NCIH2009	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.18754132128976625	[686]	[1273,639,701]	-3	hSpCas9	negative selection	7886034
47545679	47545702	19	+	27260156	NCIH2009	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.18149460690181707	[807]	[1331,950,768]	-3	hSpCas9	negative selection	7886035
47549342	47549365	19	+	27260156	NCIH2009	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.20680049302268588	[1174]	[2501,1611,1691]	3	hSpCas9	negative selection	7886036
47540244	47540267	19	+	27260156	NCIH2009	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.040094329551316976	[216]	[252,175,448]	0	hSpCas9	negative selection	7950282
47549462	47549485	19	+	27260156	NCIH2009	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	0.1097610989903357	[762]	[1066,1286,1075]	1	hSpCas9	negative selection	7950283
47540175	47540198	19	-	27260156	NCIH2009	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	0.18143348534335058	[201]	[308,452,192]	2	hSpCas9	negative selection	7950284
47545884	47545907	19	-	27260156	NCIH1373	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.42638685197189824	[686]	[533,342,1091,81]	-4	hSpCas9	negative selection	8007285
47545679	47545702	19	+	27260156	NCIH1373	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.25364906009429067	[807]	[1077,496,730,212]	-3	hSpCas9	negative selection	8007286
47549342	47549365	19	+	27260156	NCIH1373	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.12236372683735675	[1174]	[1648,1074,1968,281]	1	hSpCas9	negative selection	8007287
47540244	47540267	19	+	27260156	NCIH1373	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.6369244621282157	[216]	[172,47,140,74]	-6	hSpCas9	negative selection	8071533
47549462	47549485	19	+	27260156	NCIH1373	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.10560569801554076	[762]	[1069,680,542,249]	-1	hSpCas9	negative selection	8071534
47540175	47540198	19	-	27260156	NCIH1373	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	0.28983374392886885	[201]	[397,108,331,79]	3	hSpCas9	negative selection	8071535
47545884	47545907	19	-	27260156	PATU8902	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.3786765316607441	[686]	[810,953,595,595]	-4	hSpCas9	negative selection	8128536
47545679	47545702	19	+	27260156	PATU8902	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.2574540319542229	[807]	[1210,1444,837,2099]	2	hSpCas9	negative selection	8128537
47549342	47549365	19	+	27260156	PATU8902	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.222112070812291	[1174]	[1785,1915,2073,1787]	2	hSpCas9	negative selection	8128538
47540244	47540267	19	+	27260156	PATU8902	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.16917720159772798	[216]	[383,171,305,189]	-2	hSpCas9	negative selection	8192784
47549462	47549485	19	+	27260156	PATU8902	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.12045596789842794	[762]	[1429,714,929,812]	-1	hSpCas9	negative selection	8192785
47540175	47540198	19	-	27260156	PATU8902	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-1.2172171914623704	[201]	[61,124,116,188]	-8	hSpCas9	negative selection	8192786
47545884	47545907	19	-	27260156	PANC1	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.05910969282913864	[686]	[554,672,400,635]	-1	hSpCas9	negative selection	8249787
47545679	47545702	19	+	27260156	PANC1	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.2124939143198945	[807]	[868,1153,823,480]	3	hSpCas9	negative selection	8249788
47549342	47549365	19	+	27260156	PANC1	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.3034879611910506	[1174]	[1207,1645,1433,827]	5	hSpCas9	negative selection	8249789
47540244	47540267	19	+	27260156	PANC1	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	0.20693054960660606	[216]	[142,335,227,181]	3	hSpCas9	negative selection	8314035
47549462	47549485	19	+	27260156	PANC1	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.2011648561675845	[762]	[639,757,550,388]	-3	hSpCas9	negative selection	8314036
47540175	47540198	19	-	27260156	PANC1	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.02814783881117644	[201]	[127,101,235,194]	0	hSpCas9	negative selection	8314037
47545884	47545907	19	-	27260156	PANC0813	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.2860042092972652	[686]	[605,770,587,674]	-4	hSpCas9	negative selection	8371038
47545679	47545702	19	+	27260156	PANC0813	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.09119949717507503	[807]	[804,960,992,800]	-1	hSpCas9	negative selection	8371039
47549342	47549365	19	+	27260156	PANC0813	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	-0.2001840500289196	[1174]	[1201,1188,1285,1130]	-3	hSpCas9	negative selection	8371040
47540244	47540267	19	+	27260156	PANC0813	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.34637213252171817	[216]	[363,169,146,138]	-5	hSpCas9	negative selection	8435286
47549462	47549485	19	+	27260156	PANC0813	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.4288422993690856	[762]	[636,651,591,771]	-6	hSpCas9	negative selection	8435287
47540175	47540198	19	-	27260156	PANC0813	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.24006663246872129	[201]	[247,285,209,70]	-4	hSpCas9	negative selection	8435288
47545884	47545907	19	-	27260156	RDES	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.5209819942130852	[686]	[399,550,595,695]	-7	hSpCas9	negative selection	8492289
47545679	47545702	19	+	27260156	RDES	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.175735493658001	[807]	[656,748,1053,863]	-3	hSpCas9	negative selection	8492290
47549342	47549365	19	+	27260156	RDES	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.12487713539055623	[1174]	[1238,1403,1666,1625]	2	hSpCas9	negative selection	8492291
47540244	47540267	19	+	27260156	RDES	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.11952090957986683	[216]	[172,174,223,380]	-2	hSpCas9	negative selection	8556537
47549462	47549485	19	+	27260156	RDES	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.1742140763074741	[762]	[658,865,788,790]	-3	hSpCas9	negative selection	8556538
47540175	47540198	19	-	27260156	RDES	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.18718459097078188	[201]	[166,187,201,272]	-3	hSpCas9	negative selection	8556539
47545884	47545907	19	-	27260156	PC3	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.33705326474493746	[686]	[510,378,922,446]	-6	hSpCas9	negative selection	8613540
47545679	47545702	19	+	27260156	PC3	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.20198217271312358	[807]	[382,827,1415,514]	-4	hSpCas9	negative selection	8613541
47549342	47549365	19	+	27260156	PC3	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.34353623318693116	[1174]	[1227,1379,2238,1315]	7	hSpCas9	negative selection	8613542
47540244	47540267	19	+	27260156	PC3	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	0.3442479158558397	[216]	[121,195,570,381]	7	hSpCas9	negative selection	8677788
47549462	47549485	19	+	27260156	PC3	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.20421628503682082	[762]	[569,616,1056,499]	-4	hSpCas9	negative selection	8677789
47540175	47540198	19	-	27260156	PC3	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.5931789896707533	[201]	[62,80,337,156]	-8	hSpCas9	negative selection	8677790
47545884	47545907	19	-	27260156	PATU8988T	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.8452222517926812	[686]	[234,445,357,452]	-8	hSpCas9	negative selection	8734791
47545679	47545702	19	+	27260156	PATU8988T	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.21678221615844107	[807]	[754,664,611,653]	-4	hSpCas9	negative selection	8734792
47549342	47549365	19	+	27260156	PATU8988T	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.17536547497448662	[1174]	[1089,1154,1528,1343]	3	hSpCas9	negative selection	8734793
47540244	47540267	19	+	27260156	PATU8988T	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.5243034974863301	[216]	[134,127,192,122]	-7	hSpCas9	negative selection	8799039
47549462	47549485	19	+	27260156	PATU8988T	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.5100604151503023	[762]	[379,567,463,676]	-7	hSpCas9	negative selection	8799040
47540175	47540198	19	-	27260156	PATU8988T	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.041379025823707005	[201]	[258,142,61,300]	0	hSpCas9	negative selection	8799041
47545884	47545907	19	-	27260156	T47D	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.5780471247573294	[686]	[512,482,505,650]	-8	hSpCas9	negative selection	8856042
47545679	47545702	19	+	27260156	T47D	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.09897114697647313	[807]	[814,958,883,848]	-2	hSpCas9	negative selection	8856043
47549342	47549365	19	+	27260156	T47D	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.15009539892312396	[1174]	[1641,1292,1508,1655]	3	hSpCas9	negative selection	8856044
47540244	47540267	19	+	27260156	T47D	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.24338302192937578	[216]	[193,199,200,261]	-5	hSpCas9	negative selection	8920290
47549462	47549485	19	+	27260156	T47D	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.2728884766640818	[762]	[690,577,759,932]	-5	hSpCas9	negative selection	8920291
47540175	47540198	19	-	27260156	T47D	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.043403360846006045	[201]	[158,177,258,323]	-1	hSpCas9	negative selection	8920292
47545884	47545907	19	-	27260156	SU8686	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.33171542813248267	[686]	[465,366,620,778]	-5	hSpCas9	negative selection	8977293
47545679	47545702	19	+	27260156	SU8686	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.04665722099432812	[807]	[758,523,886,1000]	-1	hSpCas9	negative selection	8977294
47549342	47549365	19	+	27260156	SU8686	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.12850784257216596	[1174]	[1209,1211,1365,1321]	2	hSpCas9	negative selection	8977295
47540244	47540267	19	+	27260156	SU8686	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.40496546856433313	[216]	[76,177,232,171]	-6	hSpCas9	negative selection	9041541
47549462	47549485	19	+	27260156	SU8686	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.20140300554023777	[762]	[626,492,667,903]	-4	hSpCas9	negative selection	9041542
47540175	47540198	19	-	27260156	SU8686	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.1108646229469239	[201]	[99,221,176,257]	-2	hSpCas9	negative selection	9041543
47545884	47545907	19	-	27260156	SKES1	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.7090897525054427	[686]	[379,563,450,302]	-9	hSpCas9	negative selection	9098544
47545679	47545702	19	+	27260156	SKES1	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.14727255855595844	[807]	[739,819,634,722]	-3	hSpCas9	negative selection	9098545
47549342	47549365	19	+	27260156	SKES1	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.15465589437901706	[1174]	[1232,1434,1346,1206]	3	hSpCas9	negative selection	9098546
47540244	47540267	19	+	27260156	SKES1	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	0.03770642497377685	[216]	[140,242,353,146]	0	hSpCas9	negative selection	9162792
47549462	47549485	19	+	27260156	SKES1	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.5946578158707161	[762]	[507,624,490,412]	-8	hSpCas9	negative selection	9162793
47540175	47540198	19	-	27260156	SKES1	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	0.16422832004135146	[201]	[223,281,238,168]	3	hSpCas9	negative selection	9162794
47545884	47545907	19	-	27260156	TOV112D	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.7042639751016793	[686]	[327,609,374,413]	-8	hSpCas9	negative selection	9219795
47545679	47545702	19	+	27260156	TOV112D	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.1102925031504316	[807]	[991,733,680,610]	-2	hSpCas9	negative selection	9219796
47549342	47549365	19	+	27260156	TOV112D	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.15343015482735578	[1174]	[1590,1268,1249,1141]	3	hSpCas9	negative selection	9219797
47540244	47540267	19	+	27260156	TOV112D	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.06101556614478554	[216]	[218,241,129,249]	-1	hSpCas9	negative selection	9284043
47549462	47549485	19	+	27260156	TOV112D	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.3988833990423354	[762]	[548,545,502,704]	-7	hSpCas9	negative selection	9284044
47540175	47540198	19	-	27260156	TOV112D	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.2728365692849539	[201]	[243,93,155,163]	-5	hSpCas9	negative selection	9284045
47545884	47545907	19	-	27260156	TC71	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.23856717720994536	[686]	[601,573,563,767]	-6	hSpCas9	negative selection	9341046
47545679	47545702	19	+	27260156	TC71	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	-0.3389436405098402	[807]	[612,781,625,723]	-7	hSpCas9	negative selection	9341047
47549342	47549365	19	+	27260156	TC71	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.24980746943163634	[1174]	[1242,1655,1286,1837]	6	hSpCas9	negative selection	9341048
47540244	47540267	19	+	27260156	TC71	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.13844803997060384	[216]	[174,151,304,210]	-4	hSpCas9	negative selection	9405294
47549462	47549485	19	+	27260156	TC71	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.10067242988840863	[762]	[817,708,668,862]	-3	hSpCas9	negative selection	9405295
47540175	47540198	19	-	27260156	TC71	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.09994060000860472	[201]	[216,230,210,144]	-3	hSpCas9	negative selection	9405296
47545884	47545907	19	-	27260156	TC32	viability	GCGACTACCGCTCTCTGCGCCGG	ZNF541	ENSG00000118156	-0.551049268249416	[686]	[490,201,607,556]	-8	hSpCas9	negative selection	9462297
47545679	47545702	19	+	27260156	TC32	viability	GGACGATGCTACTCACGATGCGG	ZNF541	ENSG00000118156	0.022375065728983734	[807]	[538,840,896,782]	0	hSpCas9	negative selection	9462298
47549342	47549365	19	+	27260156	TC32	viability	TGCTGAACACCTTCCCGCACAGG	ZNF541	ENSG00000118156	0.19958803453610652	[1174]	[1213,980,1466,1495]	3	hSpCas9	negative selection	9462299
47540244	47540267	19	+	27260156	TC32	viability	CTTTCTCCGTATAAAACATCTGG	ZNF541	ENSG00000118156	-0.08789099048889537	[216]	[244,95,275,182]	-1	hSpCas9	negative selection	9526545
47549462	47549485	19	+	27260156	TC32	viability	CCTTAAGCACACCTAGCCCCAGG	ZNF541	ENSG00000118156	-0.2102836401968881	[762]	[741,378,756,665]	-4	hSpCas9	negative selection	9526546
47540175	47540198	19	-	27260156	TC32	viability	TCGAGGGAAGCAGGAACCGCAGG	ZNF541	ENSG00000118156	-0.027743794565047164	[201]	[146,207,176,195]	0	hSpCas9	negative selection	9526547
47539687	47539710	19	+	27869803	HPAFII	viability after 27 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.44598718581424746	[614]	[422,454,NaN]	3	hSpCas9	negative selection	9568797
47540293	47540316	19	-	27869803	HPAFII	viability after 27 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	-0.34929604200255204	[277]	[21,191,NaN]	-3	hSpCas9	negative selection	9568798
47540906	47540929	19	+	27869803	HPAFII	viability after 27 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.6506409466180121	[126]	[118,92,NaN]	5	hSpCas9	negative selection	9568799
47545923	47545946	19	+	27869803	HPAFII	viability after 27 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	-0.3576002374164914	[332]	[230,57,NaN]	-3	hSpCas9	negative selection	9568800
47549252	47549275	19	-	27869803	HPAFII	viability after 27 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	-1.1551305965338519	[185]	[20,62,NaN]	-7	hSpCas9	negative selection	9568801
47555752	47555775	19	-	27869803	HPAFII	viability after 27 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	0.42718173686427274	[316]	[330,134,NaN]	3	hSpCas9	negative selection	9568802
47539687	47539710	19	+	27869803	HPAFII	viability after 15 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	-0.030101776243957268	[614]	[761,575,NaN]	0	hSpCas9	negative selection	9651246
47540293	47540316	19	-	27869803	HPAFII	viability after 15 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.10028664139832005	[277]	[138,432,NaN]	1	hSpCas9	negative selection	9651247
47540906	47540929	19	+	27869803	HPAFII	viability after 15 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	1.06059315575696	[126]	[362,235,NaN]	9	hSpCas9	negative selection	9651248
47545923	47545946	19	+	27869803	HPAFII	viability after 15 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	-0.5388811482419502	[332]	[426,133,NaN]	-5	hSpCas9	negative selection	9651249
47549252	47549275	19	-	27869803	HPAFII	viability after 15 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	-0.5112488732150587	[185]	[167,122,NaN]	-5	hSpCas9	negative selection	9651250
47555752	47555775	19	-	27869803	HPAFII	viability after 15 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	0.8148476192685733	[316]	[713,527,NaN]	8	hSpCas9	negative selection	9651251
47539687	47539710	19	+	27869803	ASPC1	viability after 36 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	-0.0726970033415486	[1414]	[416,695,321]	0	hSpCas9	negative selection	9733695
47540293	47540316	19	-	27869803	ASPC1	viability after 36 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.01070209364935748	[1030]	[364,407,320]	0	hSpCas9	negative selection	9733696
47540906	47540929	19	+	27869803	ASPC1	viability after 36 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	-0.9537452150814274	[338]	[38,55,79]	-7	hSpCas9	negative selection	9733697
47545923	47545946	19	+	27869803	ASPC1	viability after 36 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	0.5995861624708942	[765]	[649,422,214]	6	hSpCas9	negative selection	9733698
47549252	47549275	19	-	27869803	ASPC1	viability after 36 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	-0.19544465862478544	[359]	[219,70,61]	-2	hSpCas9	negative selection	9733699
47555752	47555775	19	-	27869803	ASPC1	viability after 36 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-0.4224461136781209	[746]	[169,192,210]	-4	hSpCas9	negative selection	9733700
47539687	47539710	19	+	27869803	PATU8988S	viability after 35 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	-0.13675715939351973	[1541]	[509,619,NaN]	-1	hSpCas9	negative selection	9816144
47540293	47540316	19	-	27869803	PATU8988S	viability after 35 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.011244546362756513	[932]	[468,287,NaN]	0	hSpCas9	negative selection	9816145
47540906	47540929	19	+	27869803	PATU8988S	viability after 35 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.30621040231295993	[318]	[95,221,NaN]	3	hSpCas9	negative selection	9816146
47545923	47545946	19	+	27869803	PATU8988S	viability after 35 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	-0.04012798119677369	[631]	[271,222,NaN]	0	hSpCas9	negative selection	9816147
47549252	47549275	19	-	27869803	PATU8988S	viability after 35 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	-0.1958169073663698	[299]	[100,109,NaN]	-2	hSpCas9	negative selection	9816148
47555752	47555775	19	-	27869803	PATU8988S	viability after 35 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-0.7662901446820829	[797]	[169,207,NaN]	-6	hSpCas9	negative selection	9816149
47539687	47539710	19	+	27869803	PATU8988S	viability after 31 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	-0.4284775934770022	[1541]	[411,513,NaN]	-5	hSpCas9	negative selection	9898593
47540293	47540316	19	-	27869803	PATU8988S	viability after 31 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	-0.15265570101606196	[932]	[302,374,NaN]	-2	hSpCas9	negative selection	9898594
47540906	47540929	19	+	27869803	PATU8988S	viability after 31 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.33345456306680776	[318]	[132,194,NaN]	4	hSpCas9	negative selection	9898595
47545923	47545946	19	+	27869803	PATU8988S	viability after 31 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	-0.4803081022185705	[631]	[199,155,NaN]	-5	hSpCas9	negative selection	9898596
47549252	47549275	19	-	27869803	PATU8988S	viability after 31 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	0.19525069861918987	[299]	[132,141,NaN]	2	hSpCas9	negative selection	9898597
47555752	47555775	19	-	27869803	PATU8988S	viability after 31 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	-0.5818815202845322	[797]	[139,304,NaN]	-6	hSpCas9	negative selection	9898598
47539687	47539710	19	+	27869803	HPAFII	viability after 35 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	0.36744882756209685	[614]	[292,523,NaN]	2	hSpCas9	negative selection	9981042
47540293	47540316	19	-	27869803	HPAFII	viability after 35 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	-0.1500998436066333	[277]	[20,245,NaN]	-1	hSpCas9	negative selection	9981043
47540906	47540929	19	+	27869803	HPAFII	viability after 35 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	1.0536512285928732	[126]	[108,160,NaN]	7	hSpCas9	negative selection	9981044
47545923	47545946	19	+	27869803	HPAFII	viability after 35 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	-0.8234780011413774	[332]	[146,36,NaN]	-5	hSpCas9	negative selection	9981045
47549252	47549275	19	-	27869803	HPAFII	viability after 35 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	-0.7869515699596117	[185]	[23,88,NaN]	-4	hSpCas9	negative selection	9981046
47555752	47555775	19	-	27869803	HPAFII	viability after 35 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	0.7458900726857703	[316]	[286,248,NaN]	5	hSpCas9	negative selection	9981047
47539687	47539710	19	+	27869803	HPAFII	viability after 31 days	AGGCCGACAAGCACCCACCATGG	ZNF541	ENSG00000118156	-0.12595423500647174	[614]	[199,442,NaN]	-1	hSpCas9	negative selection	10063491
47540293	47540316	19	-	27869803	HPAFII	viability after 31 days	CCACAGACTGGACGAAGCCCAGG	ZNF541	ENSG00000118156	0.22522254672345543	[277]	[0,379,NaN]	1	hSpCas9	negative selection	10063492
47540906	47540929	19	+	27869803	HPAFII	viability after 31 days	CATTCTCTTCCTTCACCGGATGG	ZNF541	ENSG00000118156	0.9448982913047255	[126]	[152,119,NaN]	7	hSpCas9	negative selection	10063493
47545923	47545946	19	+	27869803	HPAFII	viability after 31 days	GCCCTGCTCGATGCACACGAAGG	ZNF541	ENSG00000118156	-0.432190599188996	[332]	[160,113,NaN]	-3	hSpCas9	negative selection	10063494
47549252	47549275	19	-	27869803	HPAFII	viability after 31 days	CAGCAAGGCCTTTAAGCGCCAGG	ZNF541	ENSG00000118156	-1.3695042235683412	[185]	[26,54,NaN]	-7	hSpCas9	negative selection	10063495
47555752	47555775	19	-	27869803	HPAFII	viability after 31 days	ACTGCAGCGACACCCTCAACCGG	ZNF541	ENSG00000118156	0.5313382090989065	[316]	[337,168,NaN]	4	hSpCas9	negative selection	10063496
47538443	47538466	19	+	28162770	P31FUJ	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	-0.2328022044143787	[66]	[66]	-2	hSpCas9	negative selection	10271244
47545520	47545543	19	-	28162770	P31FUJ	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.08400994525066352	[451]	[562]	0	hSpCas9	negative selection	10271245
47538418	47538441	19	-	28162770	P31FUJ	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-1.0898442505723356	[95]	[52]	-6	hSpCas9	negative selection	10271246
47521859	47521882	19	-	28162770	P31FUJ	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-3.1869985148012536	[340]	[43]	-9	hSpCas9	negative selection	10271247
47555784	47555807	19	+	28162770	P31FUJ	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	0.2741577843055045	[75]	[107]	3	hSpCas9	negative selection	10271248
47549424	47549447	19	-	28162770	P31FUJ	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	-0.3328691595183009	[193]	[180]	-3	hSpCas9	negative selection	10271249
47549403	47549426	19	-	28162770	P31FUJ	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-2.0818966348266637	[262]	[72]	-8	hSpCas9	negative selection	10271250
47549351	47549374	19	-	28162770	P31FUJ	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	-3.1869985148012536	[30]	[3]	-9	hSpCas9	negative selection	10271251
47545620	47545643	19	-	28162770	P31FUJ	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	0.4915633529721941	[45]	[75]	5	hSpCas9	negative selection	10271252
47545578	47545601	19	+	28162770	P31FUJ	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-1.265223682106756	[269]	[131]	-7	hSpCas9	negative selection	10271253
47538443	47538466	19	+	28162770	TF1	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10440610
47545520	47545543	19	-	28162770	TF1	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	NaN	[NaN]	[308]	1	hSpCas9	negative selection	10440611
47538418	47538441	19	-	28162770	TF1	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10440612
47521859	47521882	19	-	28162770	TF1	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10440613
47555784	47555807	19	+	28162770	TF1	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	NaN	[NaN]	[104]	1	hSpCas9	negative selection	10440614
47549424	47549447	19	-	28162770	TF1	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	NaN	[NaN]	[232]	1	hSpCas9	negative selection	10440615
47549403	47549426	19	-	28162770	TF1	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	NaN	[NaN]	[59]	1	hSpCas9	negative selection	10440616
47549351	47549374	19	-	28162770	TF1	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10440617
47545620	47545643	19	-	28162770	TF1	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10440618
47545578	47545601	19	+	28162770	TF1	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10440619
47538443	47538466	19	+	28162770	SKM1	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	0.1290887014970481	[14]	[28]	1	hSpCas9	negative selection	10609976
47545520	47545543	19	-	28162770	SKM1	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.41179548658669174	[107]	[253]	4	hSpCas9	negative selection	10609977
47538418	47538441	19	-	28162770	SKM1	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-1.5589672921882118	[29]	[17]	-8	hSpCas9	negative selection	10609978
47521859	47521882	19	-	28162770	SKM1	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-2.6125483323930556	[127]	[36]	-9	hSpCas9	negative selection	10609979
47555784	47555807	19	+	28162770	SKM1	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	0.5105736410648652	[26]	[67]	5	hSpCas9	negative selection	10609980
47549424	47549447	19	-	28162770	SKM1	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	0.1779983019779945	[46]	[93]	1	hSpCas9	negative selection	10609981
47549403	47549426	19	-	28162770	SKM1	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-1.8220016980220055	[61]	[30]	-8	hSpCas9	negative selection	10609982
47549351	47549374	19	-	28162770	SKM1	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	-0.5809935985182104	[10]	[12]	-4	hSpCas9	negative selection	10609983
47545620	47545643	19	-	28162770	SKM1	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	0.7629608026991508	[13]	[41]	7	hSpCas9	negative selection	10609984
47545578	47545601	19	+	28162770	SKM1	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-0.8709112985029519	[59]	[57]	-6	hSpCas9	negative selection	10609985
47538443	47538466	19	+	28162770	SKM1	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	0.1290887014970481	[14]	[28]	1	hSpCas9	negative selection	10779342
47545520	47545543	19	-	28162770	SKM1	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.41179548658669174	[107]	[253]	4	hSpCas9	negative selection	10779343
47538418	47538441	19	-	28162770	SKM1	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-1.5589672921882118	[29]	[17]	-8	hSpCas9	negative selection	10779344
47521859	47521882	19	-	28162770	SKM1	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-2.6125483323930556	[127]	[36]	-9	hSpCas9	negative selection	10779345
47555784	47555807	19	+	28162770	SKM1	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	0.5105736410648652	[26]	[67]	5	hSpCas9	negative selection	10779346
47549424	47549447	19	-	28162770	SKM1	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	0.1779983019779945	[46]	[93]	1	hSpCas9	negative selection	10779347
47549403	47549426	19	-	28162770	SKM1	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-1.8220016980220055	[61]	[30]	-8	hSpCas9	negative selection	10779348
47549351	47549374	19	-	28162770	SKM1	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	-0.5809935985182104	[10]	[12]	-4	hSpCas9	negative selection	10779349
47545620	47545643	19	-	28162770	SKM1	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	0.7629608026991508	[13]	[41]	7	hSpCas9	negative selection	10779350
47545578	47545601	19	+	28162770	SKM1	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-0.8709112985029519	[59]	[57]	-6	hSpCas9	negative selection	10779351
47538443	47538466	19	+	28162770	PL21	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	1.7186067034235695	[36]	[52]	9	hSpCas9	negative selection	10948708
47545520	47545543	19	-	28162770	PL21	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.06750184591120145	[295]	[134]	0	hSpCas9	negative selection	10948709
47538418	47538441	19	-	28162770	PL21	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-1.2148978847895238	[127]	[23]	-7	hSpCas9	negative selection	10948710
47521859	47521882	19	-	28162770	PL21	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-2.841128403882414	[460]	[27]	-9	hSpCas9	negative selection	10948711
47555784	47555807	19	+	28162770	PL21	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	-0.1534973401253804	[114]	[44]	-1	hSpCas9	negative selection	10948712
47549424	47549447	19	-	28162770	PL21	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	0.3969969437186305	[170]	[97]	3	hSpCas9	negative selection	10948713
47549403	47549426	19	-	28162770	PL21	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-1.7241330593474347	[166]	[21]	-8	hSpCas9	negative selection	10948714
47549351	47549374	19	-	28162770	PL21	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	-2.157412390128764	[40]	[3]	-8	hSpCas9	negative selection	10948715
47545620	47545643	19	-	28162770	PL21	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	-1.9373639092606147	[43]	[4]	-8	hSpCas9	negative selection	10948716
47545578	47545601	19	+	28162770	PL21	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	0.2533816357662995	[132]	[68]	2	hSpCas9	negative selection	10948717
47538443	47538466	19	+	28162770	P31FUJ	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	-0.2328022044143787	[66]	[66]	-2	hSpCas9	negative selection	11118074
47545520	47545543	19	-	28162770	P31FUJ	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.08400994525066352	[451]	[562]	0	hSpCas9	negative selection	11118075
47538418	47538441	19	-	28162770	P31FUJ	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-1.0898442505723356	[95]	[52]	-6	hSpCas9	negative selection	11118076
47521859	47521882	19	-	28162770	P31FUJ	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-3.1869985148012536	[340]	[43]	-9	hSpCas9	negative selection	11118077
47555784	47555807	19	+	28162770	P31FUJ	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	0.2741577843055045	[75]	[107]	3	hSpCas9	negative selection	11118078
47549424	47549447	19	-	28162770	P31FUJ	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	-0.3328691595183009	[193]	[180]	-3	hSpCas9	negative selection	11118079
47549403	47549426	19	-	28162770	P31FUJ	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-2.0818966348266637	[262]	[72]	-8	hSpCas9	negative selection	11118080
47549351	47549374	19	-	28162770	P31FUJ	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	-3.1869985148012536	[30]	[3]	-9	hSpCas9	negative selection	11118081
47545620	47545643	19	-	28162770	P31FUJ	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	0.4915633529721941	[45]	[75]	5	hSpCas9	negative selection	11118082
47545578	47545601	19	+	28162770	P31FUJ	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-1.265223682106756	[269]	[131]	-7	hSpCas9	negative selection	11118083
47538443	47538466	19	+	28162770	OCIAML5	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	-0.5504108710028957	[42]	[52]	-4	hSpCas9	negative selection	11287440
47545520	47545543	19	-	28162770	OCIAML5	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.7602464180021147	[208]	[638]	6	hSpCas9	negative selection	11287441
47538418	47538441	19	-	28162770	OCIAML5	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	0.23199769392447744	[49]	[105]	2	hSpCas9	negative selection	11287442
47521859	47521882	19	-	28162770	OCIAML5	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-2.8306929200714297	[200]	[50]	-8	hSpCas9	negative selection	11287443
47555784	47555807	19	+	28162770	OCIAML5	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	0.2567097750533347	[82]	[178]	2	hSpCas9	negative selection	11287444
47549424	47549447	19	-	28162770	OCIAML5	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	0.5125058614318591	[79]	[205]	4	hSpCas9	negative selection	11287445
47549403	47549426	19	-	28162770	OCIAML5	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-1.7696044106720241	[135]	[71]	-7	hSpCas9	negative selection	11287446
47549351	47549374	19	-	28162770	OCIAML5	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	0.5427930464772166	[26]	[70]	5	hSpCas9	negative selection	11287447
47545620	47545643	19	-	28162770	OCIAML5	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	0.36294632010685357	[55]	[129]	3	hSpCas9	negative selection	11287448
47545578	47545601	19	+	28162770	OCIAML5	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-0.18910155814156793	[71]	[113]	-1	hSpCas9	negative selection	11287449
47538443	47538466	19	+	28162770	EOL1	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	-0.16771073628145405	[112]	[52]	-1	hSpCas9	negative selection	11456806
47545520	47545543	19	-	28162770	EOL1	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.41701024279454424	[525]	[369]	4	hSpCas9	negative selection	11456807
47538418	47538441	19	-	28162770	EOL1	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-0.08272022889350472	[198]	[98]	0	hSpCas9	negative selection	11456808
47521859	47521882	19	-	28162770	EOL1	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-3.028735729522435	[789]	[50]	-9	hSpCas9	negative selection	11456809
47555784	47555807	19	+	28162770	EOL1	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	-0.06947832738483245	[240]	[120]	0	hSpCas9	negative selection	11456810
47549424	47549447	19	-	28162770	EOL1	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	0.8334957914426315	[326]	[306]	7	hSpCas9	negative selection	11456811
47549403	47549426	19	-	28162770	EOL1	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-1.2292575645085007	[266]	[59]	-7	hSpCas9	negative selection	11456812
47549351	47549374	19	-	28162770	EOL1	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	-2.6604147291506215	[47]	[3]	-9	hSpCas9	negative selection	11456813
47545620	47545643	19	-	28162770	EOL1	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	-0.0203106742370045	[76]	[39]	0	hSpCas9	negative selection	11456814
47545578	47545601	19	+	28162770	EOL1	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-1.2849055940584155	[221]	[47]	-7	hSpCas9	negative selection	11456815
47538443	47538466	19	+	28162770	MOLM13	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	0.58109999199257	[97]	[105]	4	hSpCas9	negative selection	11626172
47545520	47545543	19	-	28162770	MOLM13	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.0931693374532232	[493]	[380]	0	hSpCas9	negative selection	11626173
47538418	47538441	19	-	28162770	MOLM13	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-2.2775377913698236	[113]	[16]	-8	hSpCas9	negative selection	11626174
47521859	47521882	19	-	28162770	MOLM13	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-5.021495459194346	[583]	[12]	-9	hSpCas9	negative selection	11626175
47555784	47555807	19	+	28162770	MOLM13	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	0.16410863336747572	[157]	[127]	1	hSpCas9	negative selection	11626176
47549424	47549447	19	-	28162770	MOLM13	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	1.2548956582103805	[203]	[351]	8	hSpCas9	negative selection	11626177
47549403	47549426	19	-	28162770	MOLM13	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-4.402475338038826	[233]	[7]	-9	hSpCas9	negative selection	11626178
47549351	47549374	19	-	28162770	MOLM13	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	-1.0466837912851794	[59]	[20]	-5	hSpCas9	negative selection	11626179
47545620	47545643	19	-	28162770	MOLM13	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	0.4678893815445788	[59]	[59]	3	hSpCas9	negative selection	11626180
47545578	47545601	19	+	28162770	MOLM13	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-0.8977600907721014	[200]	[77]	-5	hSpCas9	negative selection	11626181
47538443	47538466	19	+	28162770	HEL	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	1.4346306366701564	[66]	[115]	9	hSpCas9	negative selection	11795538
47545520	47545543	19	-	28162770	HEL	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.10013034418283806	[385]	[264]	0	hSpCas9	negative selection	11795539
47538418	47538441	19	-	28162770	HEL	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	0.614169679803586	[101]	[99]	5	hSpCas9	negative selection	11795540
47521859	47521882	19	-	28162770	HEL	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-2.6624459990524287	[513]	[51]	-8	hSpCas9	negative selection	11795541
47555784	47555807	19	+	28162770	HEL	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	0.7290386783945773	[145]	[154]	6	hSpCas9	negative selection	11795542
47549424	47549447	19	-	28162770	HEL	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	0.8220625314449189	[203]	[230]	7	hSpCas9	negative selection	11795543
47549403	47549426	19	-	28162770	HEL	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-2.0963468140402184	[226]	[33]	-8	hSpCas9	negative selection	11795544
47549351	47549374	19	-	28162770	HEL	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	0.2097794247242506	[26]	[19]	1	hSpCas9	negative selection	11795545
47545620	47545643	19	-	28162770	HEL	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	0.7595524969831069	[82]	[89]	6	hSpCas9	negative selection	11795546
47545578	47545601	19	+	28162770	HEL	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-3.5085704912746083	[230]	[12]	-9	hSpCas9	negative selection	11795547
47538443	47538466	19	+	28162770	MV411	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	-0.0019219181539420482	[62]	[52]	0	hSpCas9	negative selection	11964904
47545520	47545543	19	-	28162770	MV411	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.1761201462811225	[310]	[295]	1	hSpCas9	negative selection	11964905
47538418	47538441	19	-	28162770	MV411	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-0.7641504234924364	[124]	[61]	-5	hSpCas9	negative selection	11964906
47521859	47521882	19	-	28162770	MV411	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-3.0962792328698736	[466]	[45]	-9	hSpCas9	negative selection	11964907
47555784	47555807	19	+	28162770	MV411	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	0.3629147682027112	[83]	[90]	3	hSpCas9	negative selection	11964908
47549424	47549447	19	-	28162770	MV411	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	0.7302196566974534	[155]	[217]	6	hSpCas9	negative selection	11964909
47549403	47549426	19	-	28162770	MV411	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-3.00048996266081	[246]	[25]	-9	hSpCas9	negative selection	11964910
47549351	47549374	19	-	28162770	MV411	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	-3.2761244052742375	[22]	[1]	-9	hSpCas9	negative selection	11964911
47545620	47545643	19	-	28162770	MV411	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	0.14310089096803935	[42]	[39]	1	hSpCas9	negative selection	11964912
47545578	47545601	19	+	28162770	MV411	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-2.599017190963769	[186]	[25]	-9	hSpCas9	negative selection	11964913
47538443	47538466	19	+	28162770	MONOMAC1	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	0.15290562399740515	[50]	[64]	1	hSpCas9	negative selection	12134270
47545520	47545543	19	-	28162770	MONOMAC1	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	-0.010382206959540397	[180]	[205]	0	hSpCas9	negative selection	12134271
47538418	47538441	19	-	28162770	MONOMAC1	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-0.02711184561724128	[87]	[98]	0	hSpCas9	negative selection	12134272
47521859	47521882	19	-	28162770	MONOMAC1	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-2.728228091339729	[236]	[40]	-9	hSpCas9	negative selection	12134273
47555784	47555807	19	+	28162770	MONOMAC1	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	-1.0450337536145036	[53]	[29]	-7	hSpCas9	negative selection	12134274
47549424	47549447	19	-	28162770	MONOMAC1	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	0.3346836323846232	[91]	[132]	3	hSpCas9	negative selection	12134275
47549403	47549426	19	-	28162770	MONOMAC1	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-0.7870525755069953	[142]	[94]	-6	hSpCas9	negative selection	12134276
47549351	47549374	19	-	28162770	MONOMAC1	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	0.5034028710815386	[23]	[38]	5	hSpCas9	negative selection	12134277
47545620	47545643	19	-	28162770	MONOMAC1	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	1.2343024645483904	[32]	[88]	9	hSpCas9	negative selection	12134278
47545578	47545601	19	+	28162770	MONOMAC1	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-1.2571578394971246	[97]	[46]	-7	hSpCas9	negative selection	12134279
47538443	47538466	19	+	28162770	OCIAML2	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	-0.41173613618859295	[11]	[49]	-3	hSpCas9	negative selection	12303636
47545520	47545543	19	-	28162770	OCIAML2	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.7305287616550674	[65]	[606]	7	hSpCas9	negative selection	12303637
47538418	47538441	19	-	28162770	OCIAML2	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-0.3153515997642502	[10]	[48]	-3	hSpCas9	negative selection	12303638
47521859	47521882	19	-	28162770	OCIAML2	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-2.665645807647304	[86]	[75]	-9	hSpCas9	negative selection	12303639
47555784	47555807	19	+	28162770	OCIAML2	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	-0.6446592250172102	[32]	[116]	-5	hSpCas9	negative selection	12303640
47549424	47549447	19	-	28162770	OCIAML2	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	0.07685797006033201	[25]	[151]	0	hSpCas9	negative selection	12303641
47549403	47549426	19	-	28162770	OCIAML2	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-1.011198206604864	[19]	[54]	-6	hSpCas9	negative selection	12303642
47549351	47549374	19	-	28162770	OCIAML2	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	-0.5961607073260202	[2]	[10]	-4	hSpCas9	negative selection	12303643
47545620	47545643	19	-	28162770	OCIAML2	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	1.5649940844885601	[4]	[81]	9	hSpCas9	negative selection	12303644
47545578	47545601	19	+	28162770	OCIAML2	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	-1.1625075298798293	[41]	[103]	-6	hSpCas9	negative selection	12303645
47538443	47538466	19	+	28162770	OCIAML3	viability	AAGAAGTTTAGAACCACAGGTGG	ZNF541	ENSG00000118156	0.575917361118149	[9]	[44]	5	hSpCas9	negative selection	12473002
47545520	47545543	19	-	28162770	OCIAML3	viability	GCTGGACACCGAGCTTCCCGAGG	ZNF541	ENSG00000118156	0.30620159019270654	[100]	[376]	3	hSpCas9	negative selection	12473003
47538418	47538441	19	-	28162770	OCIAML3	viability	GGGACAAGAGAAAGACGGGGAGG	ZNF541	ENSG00000118156	-0.9379620415415244	[32]	[51]	-6	hSpCas9	negative selection	12473004
47521859	47521882	19	-	28162770	OCIAML3	viability	GGAGGAAGTGGAAAGGACAGAGG	ZNF541	ENSG00000118156	-1.3645257942013957	[115]	[135]	-7	hSpCas9	negative selection	12473005
47555784	47555807	19	+	28162770	OCIAML3	viability	GGCTCTCTGAAAATGAAGGGAGG	ZNF541	ENSG00000118156	0.16087986183930525	[23]	[80]	1	hSpCas9	negative selection	12473006
47549424	47549447	19	-	28162770	OCIAML3	viability	AAGGAGGAAGGGCCACCTCGGGG	ZNF541	ENSG00000118156	0.585316059120399	[33]	[153]	5	hSpCas9	negative selection	12473007
47549403	47549426	19	-	28162770	OCIAML3	viability	GGAGTGCCAGGAAAGGAAAGCGG	ZNF541	ENSG00000118156	-0.9391431263728507	[46]	[73]	-6	hSpCas9	negative selection	12473008
47549351	47549374	19	-	28162770	OCIAML3	viability	GGACTGCAGCCTGTGCGGGAAGG	ZNF541	ENSG00000118156	0.014801602351360632	[19]	[60]	0	hSpCas9	negative selection	12473009
47545620	47545643	19	-	28162770	OCIAML3	viability	GGGCTTCAGACAGCGAAGGGAGG	ZNF541	ENSG00000118156	1.0108544178346979	[11]	[72]	8	hSpCas9	negative selection	12473010
47545578	47545601	19	+	28162770	OCIAML3	viability	GGACGAGGACCCCGATGAGGCGG	ZNF541	ENSG00000118156	0.25684892037002743	[55]	[201]	2	hSpCas9	negative selection	12473011