Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:339327
• Symbol:ZNF546
• Description:zinc finger protein 546

DataSource: http://genomecrispr.dkfz.de/#!/results/ZNF546

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
40023786	40023809	CHR_HG2021_PATCH	+	26472758	Jiyoye	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000281526	1.089985205625174	[151]	[243]	7	hSpCas9	negative selection	188177
40008519	40008542	19	+	26472758	Jiyoye	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	1.089985205625174	[151]	[243]	7	hSpCas9	negative selection	188178
40008476	40008499	19	-	26472758	Jiyoye	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	1.1914466904504362	[35]	[61]	7	hSpCas9	negative selection	188179
40023743	40023766	CHR_HG2021_PATCH	-	26472758	Jiyoye	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000281526	1.1914466904504362	[35]	[61]	7	hSpCas9	negative selection	188180
40021363	40021386	CHR_HG2021_PATCH	-	26472758	Jiyoye	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000281526	-0.6238515141147509	[46]	[22]	-4	hSpCas9	negative selection	188181
40006096	40006119	19	-	26472758	Jiyoye	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	-0.6238515141147509	[46]	[22]	-4	hSpCas9	negative selection	188182
40007302	40007325	19	+	26472758	Jiyoye	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	1.2916981640859373	[25]	[47]	7	hSpCas9	negative selection	188183
40022569	40022592	CHR_HG2021_PATCH	+	26472758	Jiyoye	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000281526	1.2916981640859373	[25]	[47]	7	hSpCas9	negative selection	188184
40022593	40022616	CHR_HG2021_PATCH	+	26472758	Jiyoye	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000281526	-0.0522562371314238	[120]	[87]	0	hSpCas9	negative selection	188185
40007326	40007349	19	+	26472758	Jiyoye	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	-0.0522562371314238	[120]	[87]	0	hSpCas9	negative selection	188186
39998314	39998337	19	+	26472758	Jiyoye	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	-0.43602851386017716	[600]	[334]	-3	hSpCas9	negative selection	188187
40013581	40013604	CHR_HG2021_PATCH	+	26472758	Jiyoye	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000281526	-0.43602851386017716	[600]	[334]	-3	hSpCas9	negative selection	188188
40013605	40013628	CHR_HG2021_PATCH	-	26472758	Jiyoye	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000281526	-0.14741347017176376	[46]	[31]	-1	hSpCas9	negative selection	188189
39998338	39998361	19	-	26472758	Jiyoye	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.14741347017176376	[46]	[31]	-1	hSpCas9	negative selection	188190
40021408	40021431	CHR_HG2021_PATCH	+	26472758	Jiyoye	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000281526	0.05925207808556654	[69]	[54]	0	hSpCas9	negative selection	188191
40006141	40006164	19	+	26472758	Jiyoye	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	0.05925207808556654	[69]	[54]	0	hSpCas9	negative selection	188192
40021377	40021400	CHR_HG2021_PATCH	+	26472758	Jiyoye	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000281526	0.2456528210592579	[320]	[286]	1	hSpCas9	negative selection	188193
40006110	40006133	19	+	26472758	Jiyoye	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	0.2456528210592579	[320]	[286]	1	hSpCas9	negative selection	188194
40021439	40021462	CHR_HG2021_PATCH	-	26472758	Jiyoye	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000281526	0.27553137569540254	[343]	[313]	2	hSpCas9	negative selection	188195
40006172	40006195	19	-	26472758	Jiyoye	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.27553137569540254	[343]	[313]	2	hSpCas9	negative selection	188196
40023786	40023809	CHR_HG2021_PATCH	+	26472758	KBM7	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000281526	-0.041486345804214064	[1085,696]	[594,225]	0	hSpCas9	negative selection	379295
40008519	40008542	19	+	26472758	KBM7	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	-0.041486345804214064	[1085,696]	[594,225]	0	hSpCas9	negative selection	379296
40008476	40008499	19	-	26472758	KBM7	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	0.24576545427482765	[144,268]	[194,51]	2	hSpCas9	negative selection	379297
40023743	40023766	CHR_HG2021_PATCH	-	26472758	KBM7	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000281526	0.24576545427482765	[144,268]	[194,51]	2	hSpCas9	negative selection	379298
40021363	40021386	CHR_HG2021_PATCH	-	26472758	KBM7	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000281526	0.7361654018135131	[94,133]	[144,43]	7	hSpCas9	negative selection	379299
40006096	40006119	19	-	26472758	KBM7	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.7361654018135131	[94,133]	[144,43]	7	hSpCas9	negative selection	379300
40007302	40007325	19	+	26472758	KBM7	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	0.6322117941648222	[151,152]	[135,89]	7	hSpCas9	negative selection	379301
40022569	40022592	CHR_HG2021_PATCH	+	26472758	KBM7	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000281526	0.6322117941648222	[151,152]	[135,89]	7	hSpCas9	negative selection	379302
40022593	40022616	CHR_HG2021_PATCH	+	26472758	KBM7	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000281526	-0.5031966816869928	[667,739]	[284,191]	-4	hSpCas9	negative selection	379303
40007326	40007349	19	+	26472758	KBM7	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	-0.5031966816869928	[667,739]	[284,191]	-4	hSpCas9	negative selection	379304
39998314	39998337	19	+	26472758	KBM7	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.4531436035226746	[1455,1154]	[852,817]	5	hSpCas9	negative selection	379305
40013581	40013604	CHR_HG2021_PATCH	+	26472758	KBM7	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000281526	0.4531436035226746	[1455,1154]	[852,817]	5	hSpCas9	negative selection	379306
40013605	40013628	CHR_HG2021_PATCH	-	26472758	KBM7	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000281526	0.45419108301922173	[225,134]	[97,127]	5	hSpCas9	negative selection	379307
39998338	39998361	19	-	26472758	KBM7	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.45419108301922173	[225,134]	[97,127]	5	hSpCas9	negative selection	379308
40021408	40021431	CHR_HG2021_PATCH	+	26472758	KBM7	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000281526	1.355236616924517	[234,261]	[423,192]	9	hSpCas9	negative selection	379309
40006141	40006164	19	+	26472758	KBM7	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	1.355236616924517	[234,261]	[423,192]	9	hSpCas9	negative selection	379310
40021377	40021400	CHR_HG2021_PATCH	+	26472758	KBM7	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000281526	0.16259991341992852	[1723,1339]	[915,695]	1	hSpCas9	negative selection	379311
40006110	40006133	19	+	26472758	KBM7	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	0.16259991341992852	[1723,1339]	[915,695]	1	hSpCas9	negative selection	379312
40021439	40021462	CHR_HG2021_PATCH	-	26472758	KBM7	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000281526	0.8689932980061423	[1437,1366]	[1638,820]	8	hSpCas9	negative selection	379313
40006172	40006195	19	-	26472758	KBM7	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.8689932980061423	[1437,1366]	[1638,820]	8	hSpCas9	negative selection	379314
40023786	40023809	CHR_HG2021_PATCH	+	26472758	Raji	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000281526	-0.032794122674660864	[431]	[97]	0	hSpCas9	negative selection	570413
40008519	40008542	19	+	26472758	Raji	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	-0.032794122674660864	[431]	[97]	0	hSpCas9	negative selection	570414
40008476	40008499	19	-	26472758	Raji	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	0.2630344058337941	[78]	[21]	2	hSpCas9	negative selection	570415
40023743	40023766	CHR_HG2021_PATCH	-	26472758	Raji	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000281526	0.2630344058337941	[78]	[21]	2	hSpCas9	negative selection	570416
40021363	40021386	CHR_HG2021_PATCH	-	26472758	Raji	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000281526	0.5410367128197904	[76]	[25]	5	hSpCas9	negative selection	570417
40006096	40006119	19	-	26472758	Raji	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.5410367128197904	[76]	[25]	5	hSpCas9	negative selection	570418
40007302	40007325	19	+	26472758	Raji	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	0.12466152680543519	[82]	[20]	1	hSpCas9	negative selection	570419
40022569	40022592	CHR_HG2021_PATCH	+	26472758	Raji	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000281526	0.12466152680543519	[82]	[20]	1	hSpCas9	negative selection	570420
40022593	40022616	CHR_HG2021_PATCH	+	26472758	Raji	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000281526	-0.1711519640003823	[261]	[53]	-1	hSpCas9	negative selection	570421
40007326	40007349	19	+	26472758	Raji	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	-0.1711519640003823	[261]	[53]	-1	hSpCas9	negative selection	570422
39998314	39998337	19	+	26472758	Raji	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.15060406397272175	[558]	[143]	1	hSpCas9	negative selection	570423
40013581	40013604	CHR_HG2021_PATCH	+	26472758	Raji	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000281526	0.15060406397272175	[558]	[143]	1	hSpCas9	negative selection	570424
40013605	40013628	CHR_HG2021_PATCH	-	26472758	Raji	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000281526	0.9963522229848556	[107]	[49]	8	hSpCas9	negative selection	570425
39998338	39998361	19	-	26472758	Raji	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.9963522229848556	[107]	[49]	8	hSpCas9	negative selection	570426
40021408	40021431	CHR_HG2021_PATCH	+	26472758	Raji	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000281526	1.448999965183074	[130]	[82]	9	hSpCas9	negative selection	570427
40006141	40006164	19	+	26472758	Raji	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	1.448999965183074	[130]	[82]	9	hSpCas9	negative selection	570428
40021377	40021400	CHR_HG2021_PATCH	+	26472758	Raji	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000281526	-0.3482959484025905	[959]	[174]	-3	hSpCas9	negative selection	570429
40006110	40006133	19	+	26472758	Raji	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	-0.3482959484025905	[959]	[174]	-3	hSpCas9	negative selection	570430
40021439	40021462	CHR_HG2021_PATCH	-	26472758	Raji	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000281526	0.1696435945349497	[838]	[218]	1	hSpCas9	negative selection	570431
40006172	40006195	19	-	26472758	Raji	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.1696435945349497	[838]	[218]	1	hSpCas9	negative selection	570432
40023786	40023809	CHR_HG2021_PATCH	+	26472758	K562	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000281526	0.6500790898627633	[655]	[868]	5	hSpCas9	negative selection	761531
40008519	40008542	19	+	26472758	K562	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.6500790898627633	[655]	[868]	5	hSpCas9	negative selection	761532
40008476	40008499	19	-	26472758	K562	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-0.1064884341926815	[87]	[68]	0	hSpCas9	negative selection	761533
40023743	40023766	CHR_HG2021_PATCH	-	26472758	K562	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000281526	-0.1064884341926815	[87]	[68]	0	hSpCas9	negative selection	761534
40021363	40021386	CHR_HG2021_PATCH	-	26472758	K562	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000281526	0.3387461102146001	[73]	[78]	2	hSpCas9	negative selection	761535
40006096	40006119	19	-	26472758	K562	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.3387461102146001	[73]	[78]	2	hSpCas9	negative selection	761536
40007302	40007325	19	+	26472758	K562	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	0.2818934330851097	[151]	[155]	2	hSpCas9	negative selection	761537
40022569	40022592	CHR_HG2021_PATCH	+	26472758	K562	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000281526	0.2818934330851097	[151]	[155]	2	hSpCas9	negative selection	761538
40022593	40022616	CHR_HG2021_PATCH	+	26472758	K562	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000281526	-0.5651506154565994	[488]	[278]	-4	hSpCas9	negative selection	761539
40007326	40007349	19	+	26472758	K562	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	-0.5651506154565994	[488]	[278]	-4	hSpCas9	negative selection	761540
39998314	39998337	19	+	26472758	K562	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.5019675944165112	[1053]	[1259]	4	hSpCas9	negative selection	761541
40013581	40013604	CHR_HG2021_PATCH	+	26472758	K562	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000281526	0.5019675944165112	[1053]	[1259]	4	hSpCas9	negative selection	761542
40013605	40013628	CHR_HG2021_PATCH	-	26472758	K562	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000281526	0.6239121100876236	[225]	[293]	5	hSpCas9	negative selection	761543
39998338	39998361	19	-	26472758	K562	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.6239121100876236	[225]	[293]	5	hSpCas9	negative selection	761544
40021408	40021431	CHR_HG2021_PATCH	+	26472758	K562	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000281526	0.18411821739863266	[341]	[327]	1	hSpCas9	negative selection	761545
40006141	40006164	19	+	26472758	K562	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	0.18411821739863266	[341]	[327]	1	hSpCas9	negative selection	761546
40021377	40021400	CHR_HG2021_PATCH	+	26472758	K562	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000281526	0.26202974350845176	[1546]	[1565]	2	hSpCas9	negative selection	761547
40006110	40006133	19	+	26472758	K562	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	0.26202974350845176	[1546]	[1565]	2	hSpCas9	negative selection	761548
40021439	40021462	CHR_HG2021_PATCH	-	26472758	K562	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000281526	0.6504110873422837	[1079]	[1430]	5	hSpCas9	negative selection	761549
40006172	40006195	19	-	26472758	K562	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.6504110873422837	[1079]	[1430]	5	hSpCas9	negative selection	761550
39998338	39998361	19	-	26627737	DLD1	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.7170152118007144	[300]	[170,112,174]	7	hSpCas9	negative selection	804756
39998339	39998362	19	-	26627737	DLD1	viability	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	-0.48378372267705294	[337]	[80,113,38]	-5	hSpCas9	negative selection	804757
40006097	40006120	19	-	26627737	DLD1	viability	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	0.5676676171770172	[557]	[285,169,307]	6	hSpCas9	negative selection	804758
40008523	40008546	19	+	26627737	DLD1	viability	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.2907386697239574	[315]	[105,111,140]	3	hSpCas9	negative selection	804759
40008524	40008547	19	+	26627737	DLD1	viability	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.3515632768191128	[623]	[192,334,225]	3	hSpCas9	negative selection	804760
40013819	40013842	19	+	26627737	DLD1	viability	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	0.13094851249584316	[81]	[22,24,34]	1	hSpCas9	negative selection	804761
39998338	39998361	19	-	26627737	GBM cells	viability after 5 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.10745564999004159	[226]	[109,115]	-2	hSpCas9	negative selection	887071
39998339	39998362	19	-	26627737	GBM cells	viability after 5 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	-0.2150423144114003	[236]	[103,114]	-3	hSpCas9	negative selection	887072
40006097	40006120	19	-	26627737	GBM cells	viability after 5 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.010985470595171187	[449]	[295,182]	0	hSpCas9	negative selection	887073
40008523	40008546	19	+	26627737	GBM cells	viability after 5 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	-0.1010861251143145	[289]	[167,121]	-1	hSpCas9	negative selection	887074
40008524	40008547	19	+	26627737	GBM cells	viability after 5 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.05686623466192198	[362]	[193,210]	0	hSpCas9	negative selection	887075
40013819	40013842	19	+	26627737	GBM cells	viability after 5 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	0.3709823192009081	[30]	[28,13]	5	hSpCas9	negative selection	887076
39998338	39998361	19	-	26627737	GBM cells	viability after 13 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.0849230709359031	[226]	[155,109]	1	hSpCas9	negative selection	969386
39998339	39998362	19	-	26627737	GBM cells	viability after 13 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	-0.42189864260611776	[236]	[63,121]	-5	hSpCas9	negative selection	969387
40006097	40006120	19	-	26627737	GBM cells	viability after 13 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.005512907794242183	[449]	[288,205]	0	hSpCas9	negative selection	969388
40008523	40008546	19	+	26627737	GBM cells	viability after 13 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.24647666339067992	[289]	[200,174]	3	hSpCas9	negative selection	969389
40008524	40008547	19	+	26627737	GBM cells	viability after 13 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.39430726646404624	[362]	[329,200]	5	hSpCas9	negative selection	969390
40013819	40013842	19	+	26627737	GBM cells	viability after 13 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	1.5643181908051322	[30]	[89,16]	9	hSpCas9	negative selection	969391
39998338	39998361	19	-	26627737	GBM cells	viability after 21 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.7336161625426525	[226]	[81,66]	-6	hSpCas9	negative selection	1051701
39998339	39998362	19	-	26627737	GBM cells	viability after 21 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	-0.13677579908769857	[236]	[137,97]	-1	hSpCas9	negative selection	1051702
40006097	40006120	19	-	26627737	GBM cells	viability after 21 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.13718375346175105	[449]	[226,217]	-1	hSpCas9	negative selection	1051703
40008523	40008546	19	+	26627737	GBM cells	viability after 21 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.38970103250795773	[289]	[231,182]	4	hSpCas9	negative selection	1051704
40008524	40008547	19	+	26627737	GBM cells	viability after 21 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.4816758940798015	[362]	[289,261]	5	hSpCas9	negative selection	1051705
40013819	40013842	19	+	26627737	GBM cells	viability after 21 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	1.0977419971163815	[30]	[34,36]	9	hSpCas9	negative selection	1051706
39998338	39998361	19	-	26627737	RPE1	viability after 9 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.9871529543707744	[631]	[341,456]	6	hSpCas9	negative selection	1134016
39998339	39998362	19	-	26627737	RPE1	viability after 9 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	-0.6482644595753245	[1128]	[204,251]	-4	hSpCas9	negative selection	1134017
40006097	40006120	19	-	26627737	RPE1	viability after 9 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.6443501380523662	[1447]	[396,151]	-4	hSpCas9	negative selection	1134018
40008523	40008546	19	+	26627737	RPE1	viability after 9 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	1.131172194371127	[549]	[391,357]	7	hSpCas9	negative selection	1134019
40008524	40008547	19	+	26627737	RPE1	viability after 9 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	-0.7963290021041177	[1572]	[159,442]	-5	hSpCas9	negative selection	1134020
40013819	40013842	19	+	26627737	RPE1	viability after 9 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	2.86932930576919	[39]	[32,166]	9	hSpCas9	negative selection	1134021
39998338	39998361	19	-	26627737	RPE1	viability after 12 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.8275927216579163	[631]	[244,360]	5	hSpCas9	negative selection	1216331
39998339	39998362	19	-	26627737	RPE1	viability after 12 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	-0.6109965464588515	[1128]	[269,122]	-4	hSpCas9	negative selection	1216332
40006097	40006120	19	-	26627737	RPE1	viability after 12 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.5695250497370967	[1447]	[368,148]	-4	hSpCas9	negative selection	1216333
40008523	40008546	19	+	26627737	RPE1	viability after 12 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	1.2455649265967161	[549]	[277,426]	7	hSpCas9	negative selection	1216334
40008524	40008547	19	+	26627737	RPE1	viability after 12 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	-0.2552367151102387	[1572]	[186,530]	-2	hSpCas9	negative selection	1216335
40013819	40013842	19	+	26627737	RPE1	viability after 12 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	3.2773947841769213	[39]	[59,150]	9	hSpCas9	negative selection	1216336
39998338	39998361	19	-	26627737	RPE1	viability after 15 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	1.3598846239877211	[631]	[325,586]	7	hSpCas9	negative selection	1298646
39998339	39998362	19	-	26627737	RPE1	viability after 15 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	-0.6206354893466357	[1128]	[251,164]	-4	hSpCas9	negative selection	1298647
40006097	40006120	19	-	26627737	RPE1	viability after 15 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.9056667383903013	[1447]	[294,144]	-5	hSpCas9	negative selection	1298648
40008523	40008546	19	+	26627737	RPE1	viability after 15 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.698432584966055	[549]	[225,277]	4	hSpCas9	negative selection	1298649
40008524	40008547	19	+	26627737	RPE1	viability after 15 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	-0.5510875252284867	[1572]	[320,286]	-3	hSpCas9	negative selection	1298650
40013819	40013842	19	+	26627737	RPE1	viability after 15 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	3.511857485656507	[39]	[124,132]	9	hSpCas9	negative selection	1298651
39998338	39998361	19	-	26627737	RPE1	viability after 18 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	1.3034989699429844	[631]	[332,514]	7	hSpCas9	negative selection	1380961
39998339	39998362	19	-	26627737	RPE1	viability after 18 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	-0.9728331712069741	[1128]	[234,69]	-6	hSpCas9	negative selection	1380962
40006097	40006120	19	-	26627737	RPE1	viability after 18 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.42810105429838863	[1447]	[375,198]	-3	hSpCas9	negative selection	1380963
40008523	40008546	19	+	26627737	RPE1	viability after 18 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.6809971004719237	[549]	[236,238]	4	hSpCas9	negative selection	1380964
40008524	40008547	19	+	26627737	RPE1	viability after 18 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	-0.5305904132436204	[1572]	[260,328]	-3	hSpCas9	negative selection	1380965
40013819	40013842	19	+	26627737	RPE1	viability after 18 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	3.8995486048194814	[39]	[61,266]	9	hSpCas9	negative selection	1380966
39998338	39998361	19	-	26627737	HeLa	viability after 8 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.6814590277191318	[275]	[286,124,186]	6	hSpCas9	negative selection	1463276
39998339	39998362	19	-	26627737	HeLa	viability after 8 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	1.4561327804798112	[218]	[160,320,278]	8	hSpCas9	negative selection	1463277
40006097	40006120	19	-	26627737	HeLa	viability after 8 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.16235162874237963	[813]	[307,298,338]	-1	hSpCas9	negative selection	1463278
40008523	40008546	19	+	26627737	HeLa	viability after 8 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.8856932733870938	[318]	[128,409,205]	7	hSpCas9	negative selection	1463279
40008524	40008547	19	+	26627737	HeLa	viability after 8 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.4391848759251173	[526]	[280,405,243]	4	hSpCas9	negative selection	1463280
40013819	40013842	19	+	26627737	HeLa	viability after 8 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	1.5164099711085883	[43]	[58,32,71]	9	hSpCas9	negative selection	1463281
39998338	39998361	19	-	26627737	HeLa	viability after 12 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.17144989747894668	[275]	[134,161,84]	1	hSpCas9	negative selection	1545591
39998339	39998362	19	-	26627737	HeLa	viability after 12 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	0.9584167191165408	[218]	[220,108,205]	7	hSpCas9	negative selection	1545592
40006097	40006120	19	-	26627737	HeLa	viability after 12 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.03177236920235349	[813]	[359,348,276]	0	hSpCas9	negative selection	1545593
40008523	40008546	19	+	26627737	HeLa	viability after 12 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.8125006175595428	[318]	[137,352,187]	6	hSpCas9	negative selection	1545594
40008524	40008547	19	+	26627737	HeLa	viability after 12 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	-0.2533175270688609	[526]	[209,219,114]	-2	hSpCas9	negative selection	1545595
40013819	40013842	19	+	26627737	HeLa	viability after 12 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	1.8363863089262895	[43]	[173,26,0]	9	hSpCas9	negative selection	1545596
39998338	39998361	19	-	26627737	HeLa	viability after 15 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.2627123139103718	[275]	[162,142,94]	2	hSpCas9	negative selection	1627906
39998339	39998362	19	-	26627737	HeLa	viability after 15 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	1.0410121424849097	[218]	[167,229,149]	7	hSpCas9	negative selection	1627907
40006097	40006120	19	-	26627737	HeLa	viability after 15 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.610791617529105	[813]	[235,218,193]	-5	hSpCas9	negative selection	1627908
40008523	40008546	19	+	26627737	HeLa	viability after 15 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	1.5614240532661359	[318]	[130,724,289]	8	hSpCas9	negative selection	1627909
40008524	40008547	19	+	26627737	HeLa	viability after 15 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.3742432125619835	[526]	[340,279,206]	3	hSpCas9	negative selection	1627910
40013819	40013842	19	+	26627737	HeLa	viability after 15 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	2.126331712626129	[43]	[131,46,52]	9	hSpCas9	negative selection	1627911
39998338	39998361	19	-	26627737	HeLa	viability after 18 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.22201258314930972	[275]	[103,115,94]	2	hSpCas9	negative selection	1710221
39998339	39998362	19	-	26627737	HeLa	viability after 18 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	1.04230825477596	[218]	[110,192,149]	7	hSpCas9	negative selection	1710222
40006097	40006120	19	-	26627737	HeLa	viability after 18 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.6308167929111674	[813]	[151,181,193]	-5	hSpCas9	negative selection	1710223
40008523	40008546	19	+	26627737	HeLa	viability after 18 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	1.5443892737923657	[318]	[88,587,289]	8	hSpCas9	negative selection	1710224
40008524	40008547	19	+	26627737	HeLa	viability after 18 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.4150605701747108	[526]	[244,230,206]	3	hSpCas9	negative selection	1710225
40013819	40013842	19	+	26627737	HeLa	viability after 18 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	2.172054929716072	[43]	[90,41,52]	9	hSpCas9	negative selection	1710226
39998338	39998361	19	-	26627737	HCT116	viability after 6 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.5354883022881193	[653]	[68,71]	-3	hSpCas9	negative selection	1792536
39998339	39998362	19	-	26627737	HCT116	viability after 6 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	1.1049309457177312	[507]	[203,153]	6	hSpCas9	negative selection	1792537
40006097	40006120	19	-	26627737	HCT116	viability after 6 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-1.0789170081617068	[1041]	[141,41]	-6	hSpCas9	negative selection	1792538
40008523	40008546	19	+	26627737	HCT116	viability after 6 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	-0.06654049804714812	[486]	[85,65]	0	hSpCas9	negative selection	1792539
40008524	40008547	19	+	26627737	HCT116	viability after 6 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	1.8542881313688353	[755]	[1159,26]	8	hSpCas9	negative selection	1792540
40013819	40013842	19	+	26627737	HCT116	viability after 6 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	-4.045205839187171	[216]	[3,0]	-9	hSpCas9	negative selection	1792541
39998338	39998361	19	-	26627737	HCT116	viability after 8 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.2318875286037557	[361]	[278,102,129]	-3	hSpCas9	negative selection	1874851
39998339	39998362	19	-	26627737	HCT116	viability after 8 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	-0.12039592123210266	[335]	[189,124,195]	-1	hSpCas9	negative selection	1874852
40006097	40006120	19	-	26627737	HCT116	viability after 8 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.04322380166021178	[531]	[270,277,303]	0	hSpCas9	negative selection	1874853
40008523	40008546	19	+	26627737	HCT116	viability after 8 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.5455466718715105	[254]	[165,196,250]	5	hSpCas9	negative selection	1874854
40008524	40008547	19	+	26627737	HCT116	viability after 8 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	1.0418715157882092	[240]	[194,362,260]	8	hSpCas9	negative selection	1874855
40013819	40013842	19	+	26627737	HCT116	viability after 8 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	-0.5077626383693594	[98]	[71,29,13]	-6	hSpCas9	negative selection	1874856
39998338	39998361	19	-	26627737	HCT116	viability after 9 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.5389917467496064	[653]	[241,262]	4	hSpCas9	negative selection	1957166
39998339	39998362	19	-	26627737	HCT116	viability after 9 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	0.28922899459304413	[507]	[272,80]	2	hSpCas9	negative selection	1957167
40006097	40006120	19	-	26627737	HCT116	viability after 9 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.71642756487403	[1041]	[127,201]	-5	hSpCas9	negative selection	1957168
40008523	40008546	19	+	26627737	HCT116	viability after 9 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.40845532121227013	[486]	[185,161]	3	hSpCas9	negative selection	1957169
40008524	40008547	19	+	26627737	HCT116	viability after 9 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	-0.006912389522680529	[755]	[177,218]	0	hSpCas9	negative selection	1957170
40013819	40013842	19	+	26627737	HCT116	viability after 9 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	-0.7710112077767599	[216]	[0,59]	-5	hSpCas9	negative selection	1957171
39998338	39998361	19	-	26627737	HCT116	viability after 12 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.2894096870503535	[361]	[149,176,140]	-3	hSpCas9	negative selection	2039481
39998339	39998362	19	-	26627737	HCT116	viability after 12 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	-0.2793248970672079	[335]	[173,104,153]	-3	hSpCas9	negative selection	2039482
40006097	40006120	19	-	26627737	HCT116	viability after 12 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.7348865831779529	[531]	[108,202,197]	-7	hSpCas9	negative selection	2039483
40008523	40008546	19	+	26627737	HCT116	viability after 12 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	-0.2504349298914981	[254]	[31,151,161]	-3	hSpCas9	negative selection	2039484
40008524	40008547	19	+	26627737	HCT116	viability after 12 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.4044739516913476	[240]	[154,207,141]	4	hSpCas9	negative selection	2039485
40013819	40013842	19	+	26627737	HCT116	viability after 12 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	-0.41937861605357374	[98]	[36,43,35]	-4	hSpCas9	negative selection	2039486
39998338	39998361	19	-	26627737	HCT116	viability after 15 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.0031389904987441097	[361]	[346,141,150]	0	hSpCas9	negative selection	2121796
39998339	39998362	19	-	26627737	HCT116	viability after 15 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	-0.15864962053761927	[335]	[211,107,202]	-2	hSpCas9	negative selection	2121797
40006097	40006120	19	-	26627737	HCT116	viability after 15 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.4051675417127229	[531]	[411,136,165]	-4	hSpCas9	negative selection	2121798
40008523	40008546	19	+	26627737	HCT116	viability after 15 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.1469831939369597	[254]	[111,176,190]	1	hSpCas9	negative selection	2121799
40008524	40008547	19	+	26627737	HCT116	viability after 15 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.6855252723902571	[240]	[223,224,218]	6	hSpCas9	negative selection	2121800
40013819	40013842	19	+	26627737	HCT116	viability after 15 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	0.03914379298684101	[98]	[118,35,27]	0	hSpCas9	negative selection	2121801
39998338	39998361	19	-	26627737	HCT116	viability after 18 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.39869279814131553	[361]	[211,110,73]	-4	hSpCas9	negative selection	2204111
39998339	39998362	19	-	26627737	HCT116	viability after 18 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	-0.5502263887798771	[335]	[99,87,147]	-5	hSpCas9	negative selection	2204112
40006097	40006120	19	-	26627737	HCT116	viability after 18 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.11427866198517822	[531]	[228,213,272]	-1	hSpCas9	negative selection	2204113
40008523	40008546	19	+	26627737	HCT116	viability after 18 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	-0.34564388226441	[254]	[54,88,149]	-3	hSpCas9	negative selection	2204114
40008524	40008547	19	+	26627737	HCT116	viability after 18 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.5831589919962563	[240]	[172,214,130]	5	hSpCas9	negative selection	2204115
40013819	40013842	19	+	26627737	HCT116	viability after 18 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	-0.11530589194966945	[98]	[56,17,59]	-1	hSpCas9	negative selection	2204116
40011310	40011333	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATTGCTTGAACCCGGGAGGTGG	ZNF546	ENSG00000187187	0.3272337489211984	[8,246]	[5,67]	1	dCas9-VP64	positive selection	2421321
40026577	40026600	CHR_HG2021_PATCH	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATTGCTTGAACCCGGGAGGTGG	ZNF546	ENSG00000281526	0.3272337489211984	[8,246]	[5,67]	1	dCas9-VP64	positive selection	2421322
39988639	39988662	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTGGGTGGATCACAAGGTCGGG	ZNF546	ENSG00000187187	7.202920170586078	[87,43]	[405,4032]	9	dCas9-VP64	positive selection	2429557
40003906	40003929	CHR_HG2021_PATCH	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTGGGTGGATCACAAGGTCGGG	ZNF546	ENSG00000281526	7.202920170586078	[87,43]	[405,4032]	9	dCas9-VP64	positive selection	2429573
40028271	40028294	CHR_HG2021_PATCH	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCATGTTAGCCGGG	ZNF546	ENSG00000281526	-0.6909980618209312	[118,65]	[15,7]	-4	dCas9-VP64	positive selection	2439236
40013004	40013027	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCATGTTAGCCGGG	ZNF546	ENSG00000187187	-0.6909980618209312	[118,65]	[15,7]	-4	dCas9-VP64	positive selection	2439237
39996889	39996912	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGGCCGGGCCACTTGAGCGTGG	ZNF546	ENSG00000187187	1.9286164134343637	[66,89]	[12,122]	6	dCas9-VP64	positive selection	2472369
40012156	40012179	CHR_HG2021_PATCH	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGGCCGGGCCACTTGAGCGTGG	ZNF546	ENSG00000281526	1.9286164134343637	[66,89]	[12,122]	6	dCas9-VP64	positive selection	2472370
39996866	39996889	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GACCGCCGAGTGTGACCCTGAGG	ZNF546	ENSG00000187187	-0.6523398516200146	[93,12]	[8,3]	-3	dCas9-VP64	positive selection	2472371
40012133	40012156	CHR_HG2021_PATCH	-	25494202	A375	resistance to PLX-4720 (puromycin)	GACCGCCGAGTGTGACCCTGAGG	ZNF546	ENSG00000281526	-0.6523398516200146	[93,12]	[8,3]	-3	dCas9-VP64	positive selection	2472372
39996936	39996959	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAACCCACGCAGGAAGCTGAGG	ZNF546	ENSG00000187187	-1.7582324857747804	[128,223]	[15,5]	-8	dCas9-VP64	positive selection	2472373
40012203	40012226	CHR_HG2021_PATCH	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAACCCACGCAGGAAGCTGAGG	ZNF546	ENSG00000281526	-1.7582324857747804	[128,223]	[15,5]	-8	dCas9-VP64	positive selection	2472374
40011310	40011333	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATTGCTTGAACCCGGGAGGTGG	ZNF546	ENSG00000187187	0.646844560450541	[111,36]	[52,24]	5	dCas9-VP64	positive selection	2516576
40026577	40026600	CHR_HG2021_PATCH	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATTGCTTGAACCCGGGAGGTGG	ZNF546	ENSG00000281526	0.646844560450541	[111,36]	[52,24]	5	dCas9-VP64	positive selection	2516577
39988639	39988662	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTGGGTGGATCACAAGGTCGGG	ZNF546	ENSG00000187187	1.0563740175773226	[49,79]	[37,48]	6	dCas9-VP64	positive selection	2524812
40003906	40003929	CHR_HG2021_PATCH	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTGGGTGGATCACAAGGTCGGG	ZNF546	ENSG00000281526	1.0563740175773226	[49,79]	[37,48]	6	dCas9-VP64	positive selection	2524828
40028271	40028294	CHR_HG2021_PATCH	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCATGTTAGCCGGG	ZNF546	ENSG00000281526	0.84274483203793	[27,27]	[10,20]	5	dCas9-VP64	positive selection	2534491
40013004	40013027	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCATGTTAGCCGGG	ZNF546	ENSG00000187187	0.84274483203793	[27,27]	[10,20]	5	dCas9-VP64	positive selection	2534492
39996889	39996912	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGGCCGGGCCACTTGAGCGTGG	ZNF546	ENSG00000187187	0.12607991654416573	[55,352]	[41,98]	1	dCas9-VP64	positive selection	2567624
40012156	40012179	CHR_HG2021_PATCH	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGGCCGGGCCACTTGAGCGTGG	ZNF546	ENSG00000281526	0.12607991654416573	[55,352]	[41,98]	1	dCas9-VP64	positive selection	2567625
39996866	39996889	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GACCGCCGAGTGTGACCCTGAGG	ZNF546	ENSG00000187187	-0.17390055376966695	[554,161]	[150,61]	-2	dCas9-VP64	positive selection	2567626
40012133	40012156	CHR_HG2021_PATCH	-	25494202	A375	resistance to PLX-4720 (zeocin)	GACCGCCGAGTGTGACCCTGAGG	ZNF546	ENSG00000281526	-0.17390055376966695	[554,161]	[150,61]	-2	dCas9-VP64	positive selection	2567627
39996936	39996959	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAACCCACGCAGGAAGCTGAGG	ZNF546	ENSG00000187187	0.22794928293967465	[314,143]	[65,107]	1	dCas9-VP64	positive selection	2567628
40012203	40012226	CHR_HG2021_PATCH	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAACCCACGCAGGAAGCTGAGG	ZNF546	ENSG00000281526	0.22794928293967465	[314,143]	[65,107]	1	dCas9-VP64	positive selection	2567629
40008476	40008499	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-0.6799034608973121	[3,4]	[3,0]	-8	hSpCas9	positive selection	3034785
40006096	40006119	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.0815663475554444	[4,4]	[4,3]	1	hSpCas9	positive selection	3034786
40014504	40014527	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCACATTCTTTACATTCGTAGGG	ZNF546	ENSG00000187187	0.18587735933666044	[4,4]	[5,3]	4	hSpCas9	positive selection	3034787
40007298	40007321	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.2259541256962617	[5,5]	[3,3]	-3	hSpCas9	positive selection	3034788
40008476	40008499	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-0.1661938921829114	[3,3]	[2,1]	-2	hSpCas9	positive selection	3102643
40006096	40006119	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	-0.12132092950800008	[4,4]	[3,1]	-2	hSpCas9	positive selection	3102644
40014504	40014527	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCACATTCTTTACATTCGTAGGG	ZNF546	ENSG00000187187	0.14578857466943562	[4,4]	[5,2]	2	hSpCas9	positive selection	3102645
40007298	40007321	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.18011666380693953	[5,5]	[4,3]	3	hSpCas9	positive selection	3102646
39998325	39998348		-	24336571	A375	resistance to PLX after 7 days	AAGAGGAGGGTCCACCTGCATGG	ZNF546	ENSG00000187187	-0.04975671112928848	[9,8]	[10,5]	-1	hSpCas9	positive selection	3157748
40007387	40007410		-	24336571	A375	resistance to PLX after 7 days	ATACCTTACCCAGTGAGACCAGG	ZNF546	ENSG00000187187	0.26720691209569625	[4,4]	[5,6]	7	hSpCas9	positive selection	3157749
39998330	39998353		+	24336571	A375	resistance to PLX after 7 days	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.22339737525042458	[16,15]	[26,10]	6	hSpCas9	positive selection	3157750
40007297	40007320		+	24336571	A375	resistance to PLX after 7 days	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.21072930258647604	[8,9]	[7,7]	-6	hSpCas9	positive selection	3157751
39998325	39998348		-	24336571	A375	resistance to PLX after 14 days	AAGAGGAGGGTCCACCTGCATGG	ZNF546	ENSG00000187187	0.06048832976157523	[13,5]	[4,4]	0	hSpCas9	positive selection	3215541
40007387	40007410		-	24336571	A375	resistance to PLX after 14 days	ATACCTTACCCAGTGAGACCAGG	ZNF546	ENSG00000187187	0.34807634529146814	[5,4]	[2,2]	3	hSpCas9	positive selection	3215542
39998330	39998353		+	24336571	A375	resistance to PLX after 14 days	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.8235415754482593	[13,16]	[16,7]	7	hSpCas9	positive selection	3215543
40007297	40007320		+	24336571	A375	resistance to PLX after 14 days	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.01309604727301239	[9,7]	[3,3]	0	hSpCas9	positive selection	3215544
39998325	39998348		-	24336571	A375	viability after 7 days	AAGAGGAGGGTCCACCTGCATGG	ZNF546	ENSG00000187187	1.8859401351822105	[1]	[9,8]	9	hSpCas9	negative selection	3273334
40007387	40007410		-	24336571	A375	viability after 7 days	ATACCTTACCCAGTGAGACCAGG	ZNF546	ENSG00000187187	0.7047913224560407	[2]	[4,4]	9	hSpCas9	negative selection	3273335
39998330	39998353		+	24336571	A375	viability after 7 days	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	2.166346963655703	[2]	[16,15]	9	hSpCas9	negative selection	3273336
40007297	40007320		+	24336571	A375	viability after 7 days	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.042829781090805596	[9]	[8,9]	0	hSpCas9	negative selection	3273337
39998325	39998348		-	24336571	A375	viability after 14 days	AAGAGGAGGGTCCACCTGCATGG	ZNF546	ENSG00000187187	2.064411549574409	[1]	[13,5]	9	hSpCas9	negative selection	3331127
40007387	40007410		-	24336571	A375	viability after 14 days	ATACCTTACCCAGTGAGACCAGG	ZNF546	ENSG00000187187	0.7582790546079252	[2]	[5,4]	8	hSpCas9	negative selection	3331128
39998330	39998353		+	24336571	A375	viability after 14 days	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	2.088073818201754	[2]	[13,16]	9	hSpCas9	negative selection	3331129
40007297	40007320		+	24336571	A375	viability after 14 days	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.11767644661854493	[9]	[9,7]	-1	hSpCas9	negative selection	3331130
40007330	40007353	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	-0.6851882938934047	[245,245]	[0,0]	-5	hSpCas9	positive selection	3403161
39998389	39998412	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	-0.0735906666687818	[160,160]	[0,0]	0	hSpCas9	positive selection	3403162
39998330	39998353	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.5240335020788246	[219,219]	[0,0]	-3	hSpCas9	positive selection	3403163
40008476	40008499	19	-	26780180	HT29	viability (Avana library 4 designs)	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-0.378307110414851	[]	[]	-6	hSpCas9	negative selection	3474130
40006096	40006119	19	-	26780180	HT29	viability (Avana library 4 designs)	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.636808363315507	[]	[]	2	hSpCas9	negative selection	3474131
40014504	40014527	19	-	26780180	HT29	viability (Avana library 4 designs)	CCACATTCTTTACATTCGTAGGG	ZNF546	ENSG00000187187	0.120721778979885	[]	[]	0	hSpCas9	negative selection	3474132
40007297	40007320	19	+	26780180	HT29	viability (Avana library 4 designs)	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.380467913641935	[]	[]	1	hSpCas9	negative selection	3474133
40006096	40006119	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	1.210945671761	[]	[]	1	hSpCas9	negative selection	3582210
40014504	40014527	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCACATTCTTTACATTCGTAGGG	ZNF546	ENSG00000187187	-3.0905183576315	[]	[]	-4	hSpCas9	negative selection	3582211
40008476	40008499	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-2.68373402393608	[]	[]	-3	hSpCas9	negative selection	3582212
40007297	40007320	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.901581500009693	[]	[]	1	hSpCas9	negative selection	3582213
40008519	40008542	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	2.95013074164756	[]	[]	4	hSpCas9	negative selection	3582214
39998314	39998337	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	4.22314987400734	[]	[]	7	hSpCas9	negative selection	3582215
40006096	40006119	19	-	26780180	A375	viability (Avana lentiGuide)	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	-0.858026005305663	[]	[]	-1	hSpCas9	negative selection	3690869
40014504	40014527	19	-	26780180	A375	viability (Avana lentiGuide)	CCACATTCTTTACATTCGTAGGG	ZNF546	ENSG00000187187	-3.68239507439101	[]	[]	-6	hSpCas9	negative selection	3690870
40008476	40008499	19	-	26780180	A375	viability (Avana lentiGuide)	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	1.71032982206155	[]	[]	2	hSpCas9	negative selection	3690871
40007297	40007320	19	+	26780180	A375	viability (Avana lentiGuide)	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.845335340632377	[]	[]	1	hSpCas9	negative selection	3690872
40008519	40008542	19	+	26780180	A375	viability (Avana lentiGuide)	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	3.08441132494053	[]	[]	3	hSpCas9	negative selection	3690873
39998314	39998337	19	+	26780180	A375	viability (Avana lentiGuide)	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	-4.41184420531391	[]	[]	-7	hSpCas9	negative selection	3690874
40006096	40006119	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	-0.3973191390852694	[5]	[3,3]	-5	hSpCas9	positive selection	3799476
40014504	40014527	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACATTCTTTACATTCGTAGGG	ZNF546	ENSG00000187187	-0.15205500014786563	[6]	[6,4]	-2	hSpCas9	positive selection	3799477
40008476	40008499	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-0.5706326605780212	[5]	[3,3]	-7	hSpCas9	positive selection	3799478
40007297	40007320	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.12642670757775612	[6]	[6,6]	3	hSpCas9	positive selection	3799479
40008519	40008542	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.15979468039947062	[5]	[6,4]	4	hSpCas9	positive selection	3799480
39998314	39998337	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.18478430204798477	[4]	[4,5]	5	hSpCas9	positive selection	3799481
40006096	40006119	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.10977238223786881	[6]	[6,4]	2	hSpCas9	positive selection	3908083
40014504	40014527	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACATTCTTTACATTCGTAGGG	ZNF546	ENSG00000187187	0.23781122621582026	[6]	[7,5]	6	hSpCas9	positive selection	3908084
40008476	40008499	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	0.17227843362533266	[5]	[5,5]	4	hSpCas9	positive selection	3908085
40007297	40007320	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.27538324696152505	[6]	[6,6]	7	hSpCas9	positive selection	3908086
40008519	40008542	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.1413502840286957	[5]	[5,4]	3	hSpCas9	positive selection	3908087
39998314	39998337	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.0724309152361175	[5]	[4,4]	1	hSpCas9	positive selection	3908088
40007330	40007353	19	-	26780180	A375	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	2.0009864946534	[]	[]	9	hSpCas9	negative selection	4016166
39998330	39998353	19	+	26780180	A375	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.789134395652226	[]	[]	3	hSpCas9	negative selection	4016167
40008524	40008547	19	-	26780180	A375	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.774341998538331	[]	[]	3	hSpCas9	negative selection	4016168
40008544	40008567	19	+	26780180	A375	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.996314955473106	[]	[]	4	hSpCas9	negative selection	4016169
40007297	40007320	19	+	26780180	A375	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.757106910024294	[]	[]	3	hSpCas9	negative selection	4016170
39998389	39998412	19	+	26780180	A375	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	1.17712604190049	[]	[]	6	hSpCas9	negative selection	4016171
40007330	40007353	19	-	26780180	HT29	viability (GeCKOv2 library)	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	1.85925703557383	[]	[]	8	hSpCas9	negative selection	4124132
39998330	39998353	19	+	26780180	HT29	viability (GeCKOv2 library)	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.667733135354033	[]	[]	2	hSpCas9	negative selection	4124133
40008524	40008547	19	-	26780180	HT29	viability (GeCKOv2 library)	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.256836394471842	[]	[]	0	hSpCas9	negative selection	4124134
40008544	40008567	19	+	26780180	HT29	viability (GeCKOv2 library)	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	1.38304031775975	[]	[]	7	hSpCas9	negative selection	4124135
40007297	40007320	19	+	26780180	HT29	viability (GeCKOv2 library)	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.361557288992126	[]	[]	1	hSpCas9	negative selection	4124136
39998389	39998412	19	+	26780180	HT29	viability (GeCKOv2 library)	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.739782993932484	[]	[]	3	hSpCas9	negative selection	4124137
39998325	39998348	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGAGGAGGGTCCACCTGCATGG	ZNF546	ENSG00000187187	0.06283706536502334	[4]	[3,2]	1	hSpCas9	positive selection	4184867
40007387	40007410	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATACCTTACCCAGTGAGACCAGG	ZNF546	ENSG00000187187	-0.3416874235214437	[3]	[1,1]	-7	hSpCas9	positive selection	4184868
39998330	39998353	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.12005877926421446	[4]	[2,3]	3	hSpCas9	positive selection	4184869
40007297	40007320	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.2173740523721408	[3]	[1,1]	-5	hSpCas9	positive selection	4184870
39998325	39998348	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGAGGAGGGTCCACCTGCATGG	ZNF546	ENSG00000187187	0.18756381183026427	[4]	[3,4,2,0]	1	hSpCas9	positive selection	4248889
40007387	40007410	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATACCTTACCCAGTGAGACCAGG	ZNF546	ENSG00000187187	0.6080280473690572	[2]	[0,1,5,0]	4	hSpCas9	positive selection	4248890
39998330	39998353	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.1513540886407515	[4]	[3,3,2,0]	1	hSpCas9	positive selection	4248891
40007297	40007320	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.7702094726490161	[2]	[0,0,0,0]	-9	hSpCas9	positive selection	4248892
40008524	40008547	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.2404903774295888	[3]	[3,2]	5	hSpCas9	positive selection	4309814
40008544	40008567	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.008310878611633377	[1]	[1,0]	0	hSpCas9	positive selection	4309815
40007297	40007320	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.32068388083790517	[2]	[2,0]	-6	hSpCas9	positive selection	4309816
40007330	40007353	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	-0.2915748555081037	[3]	[2,1]	-6	hSpCas9	positive selection	4374062
39998389	39998412	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	-0.1345850197419297	[2]	[3,0]	-3	hSpCas9	positive selection	4374063
39998330	39998353	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.5739198283680156	[3]	[4,4]	9	hSpCas9	positive selection	4374064
40006096	40006118	19	-	27760321	OCIAML3	viability	ACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.23734178515525267	[297,250]	[275,220]	2	hSpCas9	negative selection	4457144
40008523	40008545	19	-	27760321	OCIAML3	viability	CTTCCCTCATTACTATCCAGGG	ZNF546	ENSG00000187187	1.105070975063613	[166,155]	[329,195]	9	hSpCas9	negative selection	4457145
40013727	40013749	19	+	27760321	OCIAML3	viability	TTATCTCAATTGCAGACAGGGG	ZNF546	ENSG00000187187	0.2340162946651725	[235,228]	[235,185]	2	hSpCas9	negative selection	4457146
40014021	40014043	19	+	27760321	OCIAML3	viability	GGAAAGGCCTTTTGTCGAGTGG	ZNF546	ENSG00000187187	0.2206648296536109	[159,164]	[110,197]	2	hSpCas9	negative selection	4457147
40014997	40015019	19	-	27760321	OCIAML3	viability	CATATGTAGGTGCTCTCACTGG	ZNF546	ENSG00000187187	-0.024144509998074937	[326,338]	[219,305]	0	hSpCas9	negative selection	4457148
40006096	40006118	19	-	27760321	OCIAML2	viability	ACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.28932418198946697	[297,250]	[259,283]	4	hSpCas9	negative selection	4540607
40008523	40008545	19	-	27760321	OCIAML2	viability	CTTCCCTCATTACTATCCAGGG	ZNF546	ENSG00000187187	0.37985474973899214	[166,155]	[157,185]	5	hSpCas9	negative selection	4540608
40013727	40013749	19	+	27760321	OCIAML2	viability	TTATCTCAATTGCAGACAGGGG	ZNF546	ENSG00000187187	-0.0822827421335296	[235,228]	[174,181]	-1	hSpCas9	negative selection	4540609
40014021	40014043	19	+	27760321	OCIAML2	viability	GGAAAGGCCTTTTGTCGAGTGG	ZNF546	ENSG00000187187	0.6541002343315682	[159,164]	[152,279]	8	hSpCas9	negative selection	4540610
40014997	40015019	19	-	27760321	OCIAML2	viability	CATATGTAGGTGCTCTCACTGG	ZNF546	ENSG00000187187	0.13796561153943798	[326,338]	[280,319]	1	hSpCas9	negative selection	4540611
40006096	40006118	19	-	27760321	MV411	viability	ACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	1.9475045886862956	[297,250]	[1014,216]	9	hSpCas9	negative selection	4624070
40008523	40008545	19	-	27760321	MV411	viability	CTTCCCTCATTACTATCCAGGG	ZNF546	ENSG00000187187	0.7372321937749076	[166,155]	[108,280]	5	hSpCas9	negative selection	4624071
40013727	40013749	19	+	27760321	MV411	viability	TTATCTCAATTGCAGACAGGGG	ZNF546	ENSG00000187187	0.8954774912091942	[235,228]	[277,297]	6	hSpCas9	negative selection	4624072
40014021	40014043	19	+	27760321	MV411	viability	GGAAAGGCCTTTTGTCGAGTGG	ZNF546	ENSG00000187187	-0.5071751883172848	[159,164]	[66,88]	-4	hSpCas9	negative selection	4624073
40014997	40015019	19	-	27760321	MV411	viability	CATATGTAGGTGCTCTCACTGG	ZNF546	ENSG00000187187	-2.3609025404463027	[326,338]	[20,75]	-8	hSpCas9	negative selection	4624074
40006096	40006118	19	-	27760321	HL60	viability	ACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.6788205670936908	[297,250]	[377,335]	7	hSpCas9	negative selection	4707533
40008523	40008545	19	-	27760321	HL60	viability	CTTCCCTCATTACTATCCAGGG	ZNF546	ENSG00000187187	-0.5053224351669494	[166,155]	[75,110]	-5	hSpCas9	negative selection	4707534
40013727	40013749	19	+	27760321	HL60	viability	TTATCTCAATTGCAGACAGGGG	ZNF546	ENSG00000187187	-0.1527198611794307	[235,228]	[127,216]	-2	hSpCas9	negative selection	4707535
40014021	40014043	19	+	27760321	HL60	viability	GGAAAGGCCTTTTGTCGAGTGG	ZNF546	ENSG00000187187	1.2260408696002154	[159,164]	[292,331]	9	hSpCas9	negative selection	4707536
40014997	40015019	19	-	27760321	HL60	viability	CATATGTAGGTGCTCTCACTGG	ZNF546	ENSG00000187187	-0.1684953656800628	[326,338]	[265,218]	-2	hSpCas9	negative selection	4707537
40006096	40006118	19	-	27760321	HT1080	viability	ACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.07737176713170046	[250,195]	[155,25]	0	hSpCas9	negative selection	4790996
40008523	40008545	19	-	27760321	HT1080	viability	CTTCCCTCATTACTATCCAGGG	ZNF546	ENSG00000187187	-1.9355796703560433	[155,121]	[13,14]	-6	hSpCas9	negative selection	4790997
40013727	40013749	19	+	27760321	HT1080	viability	TTATCTCAATTGCAGACAGGGG	ZNF546	ENSG00000187187	1.6161247435525001	[228,178]	[304,187]	8	hSpCas9	negative selection	4790998
40014021	40014043	19	+	27760321	HT1080	viability	GGAAAGGCCTTTTGTCGAGTGG	ZNF546	ENSG00000187187	1.7182313013042658	[164,128]	[196,187]	8	hSpCas9	negative selection	4790999
40014997	40015019	19	-	27760321	HT1080	viability	CATATGTAGGTGCTCTCACTGG	ZNF546	ENSG00000187187	-1.184138289429689	[338,264]	[72,30]	-5	hSpCas9	negative selection	4791000
40006096	40006118	19	-	27760321	HT29	viability after 7 days	ACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	-0.042644247872097085	[250,195]	[274,217,340]	0	hSpCas9	negative selection	4874459
40008523	40008545	19	-	27760321	HT29	viability after 7 days	CTTCCCTCATTACTATCCAGGG	ZNF546	ENSG00000187187	0.007879104741262521	[155,121]	[179,117,238]	0	hSpCas9	negative selection	4874460
40013727	40013749	19	+	27760321	HT29	viability after 7 days	TTATCTCAATTGCAGACAGGGG	ZNF546	ENSG00000187187	-0.11200948168987068	[228,178]	[166,211,334]	-2	hSpCas9	negative selection	4874461
40014021	40014043	19	+	27760321	HT29	viability after 7 days	GGAAAGGCCTTTTGTCGAGTGG	ZNF546	ENSG00000187187	0.0928055506963843	[164,128]	[315,237,70]	1	hSpCas9	negative selection	4874462
40014997	40015019	19	-	27760321	HT29	viability after 7 days	CATATGTAGGTGCTCTCACTGG	ZNF546	ENSG00000187187	0.32318045325922035	[338,264]	[608,495,372]	5	hSpCas9	negative selection	4874463
40006096	40006118	19	-	27760321	HT29	viability after 25 days	ACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.3916661175174764	[250,195]	[227,409,377]	4	hSpCas9	negative selection	4957922
40008523	40008545	19	-	27760321	HT29	viability after 25 days	CTTCCCTCATTACTATCCAGGG	ZNF546	ENSG00000187187	-0.10426724531335796	[155,121]	[42,187,226]	-1	hSpCas9	negative selection	4957923
40013727	40013749	19	+	27760321	HT29	viability after 25 days	TTATCTCAATTGCAGACAGGGG	ZNF546	ENSG00000187187	-0.39449058913029367	[228,178]	[146,172,217]	-4	hSpCas9	negative selection	4957924
40014021	40014043	19	+	27760321	HT29	viability after 25 days	GGAAAGGCCTTTTGTCGAGTGG	ZNF546	ENSG00000187187	0.29652124879159536	[164,128]	[210,135,278]	3	hSpCas9	negative selection	4957925
40014997	40015019	19	-	27760321	HT29	viability after 25 days	CATATGTAGGTGCTCTCACTGG	ZNF546	ENSG00000187187	-0.3488964694656015	[338,264]	[215,286,317]	-3	hSpCas9	negative selection	4957926
40006096	40006118	19	-	27760321	HT29	viability after 22 days	ACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.8658428675902097	[250,195]	[425,604,381]	8	hSpCas9	negative selection	5041385
40008523	40008545	19	-	27760321	HT29	viability after 22 days	CTTCCCTCATTACTATCCAGGG	ZNF546	ENSG00000187187	0.4716270631020967	[155,121]	[229,252,184]	5	hSpCas9	negative selection	5041386
40013727	40013749	19	+	27760321	HT29	viability after 22 days	TTATCTCAATTGCAGACAGGGG	ZNF546	ENSG00000187187	-0.14754354890000787	[228,178]	[258,220,156]	-1	hSpCas9	negative selection	5041387
40014021	40014043	19	+	27760321	HT29	viability after 22 days	GGAAAGGCCTTTTGTCGAGTGG	ZNF546	ENSG00000187187	0.8054967262085571	[164,128]	[233,342,315]	8	hSpCas9	negative selection	5041388
40014997	40015019	19	-	27760321	HT29	viability after 22 days	CATATGTAGGTGCTCTCACTGG	ZNF546	ENSG00000187187	-0.3401009852495147	[338,264]	[167,323,338]	-3	hSpCas9	negative selection	5041389
40006096	40006118	19	-	27760321	HT29	viability after 19 days	ACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.24409053772725364	[250,195]	[318,348,243]	2	hSpCas9	negative selection	5124848
40008523	40008545	19	-	27760321	HT29	viability after 19 days	CTTCCCTCATTACTATCCAGGG	ZNF546	ENSG00000187187	0.725974486822462	[155,121]	[258,203,322]	7	hSpCas9	negative selection	5124849
40013727	40013749	19	+	27760321	HT29	viability after 19 days	TTATCTCAATTGCAGACAGGGG	ZNF546	ENSG00000187187	-0.0938389456397164	[228,178]	[260,201,197]	-1	hSpCas9	negative selection	5124850
40014021	40014043	19	+	27760321	HT29	viability after 19 days	GGAAAGGCCTTTTGTCGAGTGG	ZNF546	ENSG00000187187	0.4720121532045294	[164,128]	[242,290,168]	4	hSpCas9	negative selection	5124851
40014997	40015019	19	-	27760321	HT29	viability after 19 days	CATATGTAGGTGCTCTCACTGG	ZNF546	ENSG00000187187	-0.6753191637964758	[338,264]	[361,138,164]	-5	hSpCas9	negative selection	5124852
40006096	40006118	19	-	27760321	HT29	viability after 16 days	ACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.9666595634883728	[250,195]	[501,498,465]	9	hSpCas9	negative selection	5208311
40008523	40008545	19	-	27760321	HT29	viability after 16 days	CTTCCCTCATTACTATCCAGGG	ZNF546	ENSG00000187187	0.5102963626181074	[155,121]	[128,252,272]	6	hSpCas9	negative selection	5208312
40013727	40013749	19	+	27760321	HT29	viability after 16 days	TTATCTCAATTGCAGACAGGGG	ZNF546	ENSG00000187187	-0.28406004601412227	[228,178]	[191,140,230]	-3	hSpCas9	negative selection	5208313
40014021	40014043	19	+	27760321	HT29	viability after 16 days	GGAAAGGCCTTTTGTCGAGTGG	ZNF546	ENSG00000187187	0.4484260195468084	[164,128]	[329,272,78]	5	hSpCas9	negative selection	5208314
40014997	40015019	19	-	27760321	HT29	viability after 16 days	CATATGTAGGTGCTCTCACTGG	ZNF546	ENSG00000187187	0.032575407771945925	[338,264]	[387,300,352]	0	hSpCas9	negative selection	5208315
40006096	40006118	19	-	27760321	HT29	viability after 13 days	ACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.604991148631823	[250,195]	[371,431,379]	7	hSpCas9	negative selection	5291774
40008523	40008545	19	-	27760321	HT29	viability after 13 days	CTTCCCTCATTACTATCCAGGG	ZNF546	ENSG00000187187	0.5026339980844668	[155,121]	[267,199,217]	6	hSpCas9	negative selection	5291775
40013727	40013749	19	+	27760321	HT29	viability after 13 days	TTATCTCAATTGCAGACAGGGG	ZNF546	ENSG00000187187	0.06863978172598995	[228,178]	[216,301,226]	0	hSpCas9	negative selection	5291776
40014021	40014043	19	+	27760321	HT29	viability after 13 days	GGAAAGGCCTTTTGTCGAGTGG	ZNF546	ENSG00000187187	0.8590860326793988	[164,128]	[169,544,218]	9	hSpCas9	negative selection	5291777
40014997	40015019	19	-	27760321	HT29	viability after 13 days	CATATGTAGGTGCTCTCACTGG	ZNF546	ENSG00000187187	-0.28216988321075887	[338,264]	[412,314,144]	-3	hSpCas9	negative selection	5291778
40006096	40006118	19	-	27760321	HT29	viability after 10 days	ACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.5601241024064496	[250,195]	[370,383,476]	7	hSpCas9	negative selection	5375237
40008523	40008545	19	-	27760321	HT29	viability after 10 days	CTTCCCTCATTACTATCCAGGG	ZNF546	ENSG00000187187	0.10129268971713845	[155,121]	[179,257,123]	1	hSpCas9	negative selection	5375238
40013727	40013749	19	+	27760321	HT29	viability after 10 days	TTATCTCAATTGCAGACAGGGG	ZNF546	ENSG00000187187	-0.21339041635563372	[228,178]	[248,224,185]	-3	hSpCas9	negative selection	5375239
40014021	40014043	19	+	27760321	HT29	viability after 10 days	GGAAAGGCCTTTTGTCGAGTGG	ZNF546	ENSG00000187187	-0.03210135244684098	[164,128]	[176,109,247]	0	hSpCas9	negative selection	5375240
40014997	40015019	19	-	27760321	HT29	viability after 10 days	CATATGTAGGTGCTCTCACTGG	ZNF546	ENSG00000187187	-0.13749012335025895	[338,264]	[301,412,315]	-2	hSpCas9	negative selection	5375241
40006096	40006118	19	-	27760321	MOLM13	viability	ACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.7002373211431132	[297,250]	[422,103]	5	hSpCas9	negative selection	5458700
40008523	40008545	19	-	27760321	MOLM13	viability	CTTCCCTCATTACTATCCAGGG	ZNF546	ENSG00000187187	-0.2582831182059224	[166,155]	[79,72]	-2	hSpCas9	negative selection	5458701
40013727	40013749	19	+	27760321	MOLM13	viability	TTATCTCAATTGCAGACAGGGG	ZNF546	ENSG00000187187	-0.1272184602217865	[235,228]	[155,89]	-1	hSpCas9	negative selection	5458702
40014021	40014043	19	+	27760321	MOLM13	viability	GGAAAGGCCTTTTGTCGAGTGG	ZNF546	ENSG00000187187	1.7856989483073231	[159,164]	[511,151]	9	hSpCas9	negative selection	5458703
40014997	40015019	19	-	27760321	MOLM13	viability	CATATGTAGGTGCTCTCACTGG	ZNF546	ENSG00000187187	0.2977448876215747	[326,338]	[291,180]	2	hSpCas9	negative selection	5458704
39997144	39997167	19	+	27661255	K562	viability	GAAGTCCGAGCTAGGTGAGGCGG	ZNF546	ENSG00000187187	0.1767766380738215	[1010,1111]	[972,942]	6	dCas9-KRAB	negative selection	5525131
39997217	39997240	19	+	27661255	K562	viability	GGCGCTCCAGGGCCCAGACCTGG	ZNF546	ENSG00000187187	-1.478134299932575	[477,530]	[145,142]	-9	dCas9-KRAB	negative selection	5525132
40008524	40008547	19	-	27260156	BXPC3	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.6069078517769202	[698]	[1029,895,1220,1350]	9	hSpCas9	negative selection	5582274
40008544	40008567	19	+	27260156	BXPC3	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.25139441948664776	[154]	[152,165,220,242]	5	hSpCas9	negative selection	5582275
40007297	40007320	19	+	27260156	BXPC3	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.07161580257035349	[217]	[216,280,259,192]	1	hSpCas9	negative selection	5582276
40007330	40007353	19	-	27260156	BXPC3	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	-0.021534471519790294	[566]	[636,567,473,654]	0	hSpCas9	negative selection	5646522
39998389	39998412	19	+	27260156	BXPC3	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.09764711994336245	[360]	[408,405,398,396]	2	hSpCas9	negative selection	5646523
39998330	39998353	19	+	27260156	BXPC3	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.08023579518312163	[878]	[772,974,784,950]	-2	hSpCas9	negative selection	5646524
40008524	40008547	19	-	27260156	A673	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.6447611788071641	[698]	[1460,1216,1353,1228]	9	hSpCas9	negative selection	5703525
40008544	40008567	19	+	27260156	A673	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.2675000206696594	[154]	[221,197,132,350]	6	hSpCas9	negative selection	5703526
40007297	40007320	19	+	27260156	A673	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.12067991044567006	[217]	[266,251,247,374]	3	hSpCas9	negative selection	5703527
40007330	40007353	19	-	27260156	A673	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.17109639590765235	[566]	[860,681,763,770]	4	hSpCas9	negative selection	5767773
39998389	39998412	19	+	27260156	A673	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.23985174465974504	[360]	[609,434,529,482]	5	hSpCas9	negative selection	5767774
39998330	39998353	19	+	27260156	A673	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.021533368134660225	[878]	[972,1048,1024,1105]	0	hSpCas9	negative selection	5767775
40008524	40008547	19	-	27260156	A375	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.8305472204406299	[698]	[1384,1603,1514,1332]	9	hSpCas9	negative selection	5824776
40008544	40008567	19	+	27260156	A375	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.10949241971054624	[154]	[365,141,104,164]	1	hSpCas9	negative selection	5824777
40007297	40007320	19	+	27260156	A375	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.25342406262522976	[217]	[252,222,163,214]	-4	hSpCas9	negative selection	5824778
40007330	40007353	19	-	27260156	A375	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.15765540457247407	[566]	[586,835,687,840]	2	hSpCas9	negative selection	5889024
39998389	39998412	19	+	27260156	A375	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	-0.006422282237175447	[360]	[373,427,370,495]	0	hSpCas9	negative selection	5889025
39998330	39998353	19	+	27260156	A375	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.16277712283274215	[878]	[1605,1078,1100,837]	2	hSpCas9	negative selection	5889026
40008524	40008547	19	-	27260156	COLO741	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.5670969976838318	[698]	[1645,1242,1119]	9	hSpCas9	negative selection	5946027
40008544	40008567	19	+	27260156	COLO741	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.26179511421161883	[154]	[170,376,163]	5	hSpCas9	negative selection	5946028
40007297	40007320	19	+	27260156	COLO741	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.40680966237844074	[217]	[511,309,301]	8	hSpCas9	negative selection	5946029
40007330	40007353	19	-	27260156	COLO741	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.12073547114861294	[566]	[951,733,695]	2	hSpCas9	negative selection	6010275
39998389	39998412	19	+	27260156	COLO741	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.3664478882430853	[360]	[534,666,576]	7	hSpCas9	negative selection	6010276
39998330	39998353	19	+	27260156	COLO741	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.07445600417141551	[878]	[1363,1011,1183]	1	hSpCas9	negative selection	6010277
40008524	40008547	19	-	27260156	CAL120	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.5870758767398878	[698]	[1178,1346,1372]	8	hSpCas9	negative selection	6067278
40008544	40008567	19	+	27260156	CAL120	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	-0.5128106542827733	[154]	[147,100,157]	-6	hSpCas9	negative selection	6067279
40007297	40007320	19	+	27260156	CAL120	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.2282233647616443	[217]	[529,186,268]	3	hSpCas9	negative selection	6067280
40007330	40007353	19	-	27260156	CAL120	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.34243536449818845	[566]	[1060,840,807]	5	hSpCas9	negative selection	6131526
39998389	39998412	19	+	27260156	CAL120	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.8202968909779667	[360]	[662,1084,614]	9	hSpCas9	negative selection	6131527
39998330	39998353	19	+	27260156	CAL120	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.23189486277253302	[878]	[1458,862,557]	-3	hSpCas9	negative selection	6131528
40008524	40008547	19	-	27260156	CADOES1	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.8491355001632852	[698]	[1233,1022,1255,1170]	9	hSpCas9	negative selection	6188529
40008544	40008567	19	+	27260156	CADOES1	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.41060630629968076	[154]	[236,189,131,207]	6	hSpCas9	negative selection	6188530
40007297	40007320	19	+	27260156	CADOES1	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.8158891515048097	[217]	[122,107,105,123]	-8	hSpCas9	negative selection	6188531
40007330	40007353	19	-	27260156	CADOES1	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.13576249217721337	[566]	[567,506,595,648]	2	hSpCas9	negative selection	6252777
39998389	39998412	19	+	27260156	CADOES1	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.24025538770806984	[360]	[343,411,497,329]	4	hSpCas9	negative selection	6252778
39998330	39998353	19	+	27260156	CADOES1	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.13999421336137152	[878]	[783,668,731,783]	-2	hSpCas9	negative selection	6252779
40008524	40008547	19	-	27260156	EWS502	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.7938581024362854	[698]	[935,1382,1237,1634]	9	hSpCas9	negative selection	6309780
40008544	40008567	19	+	27260156	EWS502	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.4191220447242858	[154]	[110,166,268,355]	7	hSpCas9	negative selection	6309781
40007297	40007320	19	+	27260156	EWS502	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.04000827399256823	[217]	[194,194,274,238]	0	hSpCas9	negative selection	6309782
40007330	40007353	19	-	27260156	EWS502	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.36625415646360615	[566]	[687,870,940,588]	6	hSpCas9	negative selection	6374028
39998389	39998412	19	+	27260156	EWS502	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.42704460989267323	[360]	[459,516,530,555]	7	hSpCas9	negative selection	6374029
39998330	39998353	19	+	27260156	EWS502	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.0435781828998425	[878]	[612,1017,1059,1201]	0	hSpCas9	negative selection	6374030
40008524	40008547	19	-	27260156	EW8	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.5429857668270635	[698]	[961,740,841,765]	8	hSpCas9	negative selection	6431031
40008544	40008567	19	+	27260156	EW8	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.15231614885210676	[154]	[145,97,165,143]	3	hSpCas9	negative selection	6431032
40007297	40007320	19	+	27260156	EW8	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.1834961271219071	[217]	[112,226,164,110]	-3	hSpCas9	negative selection	6431033
40007330	40007353	19	-	27260156	EW8	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.07220913737491003	[566]	[632,389,447,481]	1	hSpCas9	negative selection	6495279
39998389	39998412	19	+	27260156	EW8	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.1040668986466246	[360]	[257,328,359,295]	2	hSpCas9	negative selection	6495280
39998330	39998353	19	+	27260156	EW8	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.08894022171848137	[878]	[599,1032,701,686]	1	hSpCas9	negative selection	6495281
40008524	40008547	19	-	27260156	CORL105	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.5385809561631221	[698]	[1188,1130,1319,1135]	8	hSpCas9	negative selection	6552282
40008544	40008567	19	+	27260156	CORL105	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.21994757321504244	[154]	[288,170,211,176]	4	hSpCas9	negative selection	6552283
40007297	40007320	19	+	27260156	CORL105	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.18163794417398849	[217]	[393,325,275,162]	3	hSpCas9	negative selection	6552284
40007330	40007353	19	-	27260156	CORL105	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.3022114210290118	[566]	[813,640,1048,808]	5	hSpCas9	negative selection	6616530
39998389	39998412	19	+	27260156	CORL105	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.3149258066690421	[360]	[387,546,537,625]	6	hSpCas9	negative selection	6616531
39998330	39998353	19	+	27260156	CORL105	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.18844398258512896	[878]	[931,851,979,861]	-3	hSpCas9	negative selection	6616532
40008524	40008547	19	-	27260156	HS294T	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.42030888653724496	[698]	[329,384,334,404]	5	hSpCas9	negative selection	6673533
40008544	40008567	19	+	27260156	HS294T	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.9032613537626598	[154]	[106,105,61,185]	9	hSpCas9	negative selection	6673534
40007297	40007320	19	+	27260156	HS294T	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.020836821884075096	[217]	[66,56,54,169]	0	hSpCas9	negative selection	6673535
40007330	40007353	19	-	27260156	HS294T	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.6649118683460759	[566]	[357,266,257,539]	8	hSpCas9	negative selection	6737781
39998389	39998412	19	+	27260156	HS294T	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.5402900594567432	[360]	[136,179,130,403]	7	hSpCas9	negative selection	6737782
39998330	39998353	19	+	27260156	HS294T	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.32999895257626377	[878]	[264,300,248,263]	-5	hSpCas9	negative selection	6737783
40008524	40008547	19	-	27260156	HCC44	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.42707757120472667	[698]	[1126,646,1524,1087]	7	hSpCas9	negative selection	6794784
40008544	40008567	19	+	27260156	HCC44	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.9457548096047054	[154]	[424,257,362,325]	9	hSpCas9	negative selection	6794785
40007297	40007320	19	+	27260156	HCC44	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.7882698314457222	[217]	[729,284,563,199]	9	hSpCas9	negative selection	6794786
40007330	40007353	19	-	27260156	HCC44	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	-0.07461302149116378	[566]	[909,406,710,480]	-1	hSpCas9	negative selection	6859032
39998389	39998412	19	+	27260156	HCC44	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.7148318843039718	[360]	[440,832,954,457]	9	hSpCas9	negative selection	6859033
39998330	39998353	19	+	27260156	HCC44	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.002932351750698281	[878]	[925,835,1367,913]	0	hSpCas9	negative selection	6859034
40008524	40008547	19	-	27260156	G402	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	1.0969720409808017	[698]	[2510,1998,1256,1641]	9	hSpCas9	negative selection	6916035
40008544	40008567	19	+	27260156	G402	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.4422638848506335	[154]	[568,177,139,183]	5	hSpCas9	negative selection	6916036
40007297	40007320	19	+	27260156	G402	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-1.2563725208623149	[217]	[129,200,76,47]	-8	hSpCas9	negative selection	6916037
40007330	40007353	19	-	27260156	G402	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.24664077196300338	[566]	[977,579,742,979]	3	hSpCas9	negative selection	6980283
39998389	39998412	19	+	27260156	G402	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	-0.012665606076453562	[360]	[365,636,299,442]	0	hSpCas9	negative selection	6980284
39998330	39998353	19	+	27260156	G402	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.006047001868767055	[878]	[1279,1229,726,1070]	0	hSpCas9	negative selection	6980285
40008524	40008547	19	-	27260156	L33	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.5636381220549029	[698]	[1049,411,637,1060]	9	hSpCas9	negative selection	7037286
40008544	40008567	19	+	27260156	L33	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.5274708362763318	[154]	[228,113,104,218]	9	hSpCas9	negative selection	7037287
40007297	40007320	19	+	27260156	L33	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.08328705187662155	[217]	[320,81,134,185]	1	hSpCas9	negative selection	7037288
40007330	40007353	19	-	27260156	L33	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.17809356962533596	[566]	[648,226,377,759]	4	hSpCas9	negative selection	7101534
39998389	39998412	19	+	27260156	L33	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.4346693980451799	[360]	[431,192,297,574]	8	hSpCas9	negative selection	7101535
39998330	39998353	19	+	27260156	L33	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.21435121529224155	[878]	[818,313,438,744]	-5	hSpCas9	negative selection	7101536
40008524	40008547	19	-	27260156	K562	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	1.0255938347577382	[698]	[1602,1631,1074,833]	9	hSpCas9	negative selection	7158537
40008544	40008567	19	+	27260156	K562	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.9052866852429101	[154]	[494,324,93,150]	9	hSpCas9	negative selection	7158538
40007297	40007320	19	+	27260156	K562	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-1.0633568028789293	[217]	[173,97,41,65]	-8	hSpCas9	negative selection	7158539
40007330	40007353	19	-	27260156	K562	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	-0.041677811298396206	[566]	[746,504,363,372]	0	hSpCas9	negative selection	7222785
39998389	39998412	19	+	27260156	K562	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.2994234197075881	[360]	[527,447,415,217]	4	hSpCas9	negative selection	7222786
39998330	39998353	19	+	27260156	K562	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.5459477904628289	[878]	[905,1178,1256,1185]	7	hSpCas9	negative selection	7222787
40008524	40008547	19	-	27260156	HT29	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.5827536620744798	[698]	[1208,1277,1426,1174]	9	hSpCas9	negative selection	7279788
40008544	40008567	19	+	27260156	HT29	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.058161822928463724	[154]	[140,327,202,126]	1	hSpCas9	negative selection	7279789
40007297	40007320	19	+	27260156	HT29	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.2123813261957178	[217]	[260,367,384,223]	4	hSpCas9	negative selection	7279790
40007330	40007353	19	-	27260156	HT29	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	-0.02324718886340771	[566]	[632,643,803,626]	0	hSpCas9	negative selection	7344036
39998389	39998412	19	+	27260156	HT29	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.26242601437790947	[360]	[658,490,433,524]	5	hSpCas9	negative selection	7344037
39998330	39998353	19	+	27260156	HT29	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.0049415473164704515	[878]	[898,1310,1163,905]	0	hSpCas9	negative selection	7344038
40008524	40008547	19	-	27260156	MHHES1	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.6073084976543368	[698]	[1394,1382,1053,1020]	9	hSpCas9	negative selection	7401039
40008544	40008567	19	+	27260156	MHHES1	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.6336330156122176	[154]	[274,219,242,321]	9	hSpCas9	negative selection	7401040
40007297	40007320	19	+	27260156	MHHES1	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.18340243798940126	[217]	[289,333,142,132]	-3	hSpCas9	negative selection	7401041
40007330	40007353	19	-	27260156	MHHES1	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.031141784118329907	[566]	[774,586,832,455]	0	hSpCas9	negative selection	7465287
39998389	39998412	19	+	27260156	MHHES1	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.519855177114857	[360]	[782,458,866,291]	8	hSpCas9	negative selection	7465288
39998330	39998353	19	+	27260156	MHHES1	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.09984611325146164	[878]	[1240,1258,1155,692]	1	hSpCas9	negative selection	7465289
40008524	40008547	19	-	27260156	MEWO	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.49053377284721766	[698]	[920,833,1001]	8	hSpCas9	negative selection	7522290
40008544	40008567	19	+	27260156	MEWO	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.40403058931769076	[154]	[244,168,171]	8	hSpCas9	negative selection	7522291
40007297	40007320	19	+	27260156	MEWO	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.3680034333479766	[217]	[309,190,297]	7	hSpCas9	negative selection	7522292
40007330	40007353	19	-	27260156	MEWO	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.1226348978079263	[566]	[750,589,424]	2	hSpCas9	negative selection	7586538
39998389	39998412	19	+	27260156	MEWO	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.23299303006352604	[360]	[447,315,436]	5	hSpCas9	negative selection	7586539
39998330	39998353	19	+	27260156	MEWO	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.17992910539016038	[878]	[799,723,667]	-4	hSpCas9	negative selection	7586540
40008524	40008547	19	-	27260156	LNCAPCLONEFGC	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.7395391805670599	[698]	[1035,1006,1273,946]	9	hSpCas9	negative selection	7643541
40008544	40008567	19	+	27260156	LNCAPCLONEFGC	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.46278520262084566	[154]	[157,220,194,198]	7	hSpCas9	negative selection	7643542
40007297	40007320	19	+	27260156	LNCAPCLONEFGC	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.7022751281949637	[217]	[82,125,108,165]	-8	hSpCas9	negative selection	7643543
40007330	40007353	19	-	27260156	LNCAPCLONEFGC	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.15447322380652684	[566]	[551,532,704,518]	2	hSpCas9	negative selection	7707789
39998389	39998412	19	+	27260156	LNCAPCLONEFGC	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	-0.05864419602152532	[360]	[338,296,297,319]	-1	hSpCas9	negative selection	7707790
39998330	39998353	19	+	27260156	LNCAPCLONEFGC	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.10255628766336145	[878]	[549,685,954,813]	-2	hSpCas9	negative selection	7707791
40008524	40008547	19	-	27260156	PANC0327	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.43039564810222974	[698]	[1224,683,633,854]	6	hSpCas9	negative selection	7764792
40008544	40008567	19	+	27260156	PANC0327	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	1.015859681436929	[154]	[229,161,474,257]	9	hSpCas9	negative selection	7764793
40007297	40007320	19	+	27260156	PANC0327	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.4365013592856375	[217]	[93,168,163,137]	-6	hSpCas9	negative selection	7764794
40007330	40007353	19	-	27260156	PANC0327	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.20250559714535438	[566]	[574,569,595,577]	3	hSpCas9	negative selection	7829040
39998389	39998412	19	+	27260156	PANC0327	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.18103776903226926	[360]	[449,309,312,394]	2	hSpCas9	negative selection	7829041
39998330	39998353	19	+	27260156	PANC0327	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.16485673600778905	[878]	[1036,478,754,570]	-2	hSpCas9	negative selection	7829042
40008524	40008547	19	-	27260156	NCIH2009	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.7276909521444836	[698]	[1825,1632,1430]	8	hSpCas9	negative selection	7886043
40008544	40008567	19	+	27260156	NCIH2009	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.18326479894602277	[154]	[332,161,260]	2	hSpCas9	negative selection	7886044
40007297	40007320	19	+	27260156	NCIH2009	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.6920521538289963	[217]	[235,223,113]	-7	hSpCas9	negative selection	7886045
40007330	40007353	19	-	27260156	NCIH2009	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.30207647945895766	[566]	[1335,726,940]	4	hSpCas9	negative selection	7950291
39998389	39998412	19	+	27260156	NCIH2009	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.011564092530472747	[360]	[660,540,351]	0	hSpCas9	negative selection	7950292
39998330	39998353	19	+	27260156	NCIH2009	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.08815098968399848	[878]	[1668,923,1399]	1	hSpCas9	negative selection	7950293
40008524	40008547	19	-	27260156	NCIH1373	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.9623341968790926	[698]	[1285,1060,1232,683]	8	hSpCas9	negative selection	8007294
40008544	40008567	19	+	27260156	NCIH1373	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.3870882395041908	[154]	[359,179,85,82]	4	hSpCas9	negative selection	8007295
40007297	40007320	19	+	27260156	NCIH1373	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.0170943859077195	[217]	[315,221,345,27]	0	hSpCas9	negative selection	8007296
40007330	40007353	19	-	27260156	NCIH1373	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.5202198833405846	[566]	[1467,673,415,321]	5	hSpCas9	negative selection	8071542
39998389	39998412	19	+	27260156	NCIH1373	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	-0.11226356777460827	[360]	[774,361,244,43]	-1	hSpCas9	negative selection	8071543
39998330	39998353	19	+	27260156	NCIH1373	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.0863991130439099	[878]	[1327,716,1090,295]	0	hSpCas9	negative selection	8071544
40008524	40008547	19	-	27260156	PATU8902	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.8979477750581741	[698]	[1677,2311,1753,1475]	8	hSpCas9	negative selection	8128545
40008544	40008567	19	+	27260156	PATU8902	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.6274290035747593	[154]	[618,102,340,251]	6	hSpCas9	negative selection	8128546
40007297	40007320	19	+	27260156	PATU8902	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.09077381369395643	[217]	[536,71,168,399]	-1	hSpCas9	negative selection	8128547
40007330	40007353	19	-	27260156	PATU8902	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.25859691817764263	[566]	[1300,1155,687,653]	2	hSpCas9	negative selection	8192793
39998389	39998412	19	+	27260156	PATU8902	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	-0.12452844338172747	[360]	[580,266,435,574]	-1	hSpCas9	negative selection	8192794
39998330	39998353	19	+	27260156	PATU8902	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.3808829284501829	[878]	[1515,1943,1526,1368]	4	hSpCas9	negative selection	8192795
40008524	40008547	19	-	27260156	PANC1	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	-0.10723673436362402	[698]	[387,1046,557,363]	-2	hSpCas9	negative selection	8249796
40008544	40008567	19	+	27260156	PANC1	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	-1.170004396269642	[154]	[45,64,58,65]	-9	hSpCas9	negative selection	8249797
40007297	40007320	19	+	27260156	PANC1	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-1.8260756235141247	[217]	[70,24,33,70]	-9	hSpCas9	negative selection	8249798
40007330	40007353	19	-	27260156	PANC1	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	-0.6427777454767227	[566]	[303,386,204,353]	-7	hSpCas9	negative selection	8314044
39998389	39998412	19	+	27260156	PANC1	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	-1.855700792587854	[360]	[123,74,99,45]	-9	hSpCas9	negative selection	8314045
39998330	39998353	19	+	27260156	PANC1	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-1.246269438950365	[878]	[321,277,390,275]	-9	hSpCas9	negative selection	8314046
40008524	40008547	19	-	27260156	PANC0813	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.5681661020759281	[698]	[1538,1252,1151,966]	8	hSpCas9	negative selection	8371047
40008544	40008567	19	+	27260156	PANC0813	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.5196360431779603	[154]	[332,148,211,350]	8	hSpCas9	negative selection	8371048
40007297	40007320	19	+	27260156	PANC0813	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.022567902467990786	[217]	[359,331,260,104]	0	hSpCas9	negative selection	8371049
40007330	40007353	19	-	27260156	PANC0813	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.1455818327721894	[566]	[708,753,808,674]	2	hSpCas9	negative selection	8435295
39998389	39998412	19	+	27260156	PANC0813	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	-0.1352798329677019	[360]	[378,497,356,312]	-2	hSpCas9	negative selection	8435296
39998330	39998353	19	+	27260156	PANC0813	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.16283670276085016	[878]	[866,823,1063,927]	-3	hSpCas9	negative selection	8435297
40008524	40008547	19	-	27260156	RDES	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.7988072674742004	[698]	[1170,1339,1573,1549]	9	hSpCas9	negative selection	8492298
40008544	40008567	19	+	27260156	RDES	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.3425404222677608	[154]	[137,188,289,320]	5	hSpCas9	negative selection	8492299
40007297	40007320	19	+	27260156	RDES	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.1227274845480677	[217]	[131,252,274,283]	-2	hSpCas9	negative selection	8492300
40007330	40007353	19	-	27260156	RDES	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.05532159393529135	[566]	[537,793,709,664]	0	hSpCas9	negative selection	8556546
39998389	39998412	19	+	27260156	RDES	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.3647167268921171	[360]	[376,412,585,842]	6	hSpCas9	negative selection	8556547
39998330	39998353	19	+	27260156	RDES	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.08896938825658152	[878]	[902,1034,1009,1408]	1	hSpCas9	negative selection	8556548
40008524	40008547	19	-	27260156	PC3	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.47876931954976953	[698]	[672,863,1874,852]	8	hSpCas9	negative selection	8613549
40008544	40008567	19	+	27260156	PC3	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.37324887349536495	[154]	[232,159,290,100]	7	hSpCas9	negative selection	8613550
40007297	40007320	19	+	27260156	PC3	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.4320685601303037	[217]	[198,221,326,459]	8	hSpCas9	negative selection	8613551
40007330	40007353	19	-	27260156	PC3	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.04092989960357052	[566]	[321,627,1006,594]	0	hSpCas9	negative selection	8677797
39998389	39998412	19	+	27260156	PC3	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	-0.11597856138825141	[360]	[158,372,533,390]	-3	hSpCas9	negative selection	8677798
39998330	39998353	19	+	27260156	PC3	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.030521061433375185	[878]	[636,738,1665,861]	0	hSpCas9	negative selection	8677799
40008524	40008547	19	-	27260156	PATU8988T	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.7588429545071447	[698]	[1213,1098,797,1488]	9	hSpCas9	negative selection	8734800
40008544	40008567	19	+	27260156	PATU8988T	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	-0.11586180196850182	[154]	[95,190,101,171]	-2	hSpCas9	negative selection	8734801
40007297	40007320	19	+	27260156	PATU8988T	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.015859754487457023	[217]	[329,163,114,241]	0	hSpCas9	negative selection	8734802
40007330	40007353	19	-	27260156	PATU8988T	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.19060013848341278	[566]	[732,764,259,772]	3	hSpCas9	negative selection	8799048
39998389	39998412	19	+	27260156	PATU8988T	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.7345723196341511	[360]	[596,502,736,465]	9	hSpCas9	negative selection	8799049
39998330	39998353	19	+	27260156	PATU8988T	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.014352803385773272	[878]	[806,1003,772,791]	0	hSpCas9	negative selection	8799050
40008524	40008547	19	-	27260156	T47D	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.5955835144366233	[698]	[1205,1204,1259,1252]	9	hSpCas9	negative selection	8856051
40008544	40008567	19	+	27260156	T47D	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.4848155396372875	[154]	[282,206,281,241]	8	hSpCas9	negative selection	8856052
40007297	40007320	19	+	27260156	T47D	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.10793349573717048	[217]	[250,246,229,212]	-2	hSpCas9	negative selection	8856053
40007330	40007353	19	-	27260156	T47D	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.01580181914699147	[566]	[764,585,633,694]	0	hSpCas9	negative selection	8920299
39998389	39998412	19	+	27260156	T47D	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.3083188475678779	[360]	[526,470,516,573]	6	hSpCas9	negative selection	8920300
39998330	39998353	19	+	27260156	T47D	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.0655186950850497	[878]	[1054,956,1042,1246]	1	hSpCas9	negative selection	8920301
40008524	40008547	19	-	27260156	SU8686	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.3614399827509298	[698]	[712,749,1014,1162]	6	hSpCas9	negative selection	8977302
40008544	40008567	19	+	27260156	SU8686	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	-0.49045425878676907	[154]	[71,122,128,116]	-7	hSpCas9	negative selection	8977303
40007297	40007320	19	+	27260156	SU8686	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-1.6424712982500953	[217]	[79,75,58,56]	-9	hSpCas9	negative selection	8977304
40007330	40007353	19	-	27260156	SU8686	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	-0.2224926042715822	[566]	[404,354,541,680]	-4	hSpCas9	negative selection	9041550
39998389	39998412	19	+	27260156	SU8686	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	-1.0550345870456044	[360]	[233,205,98,127]	-8	hSpCas9	negative selection	9041551
39998330	39998353	19	+	27260156	SU8686	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.6709468078252387	[878]	[563,417,654,569]	-7	hSpCas9	negative selection	9041552
40008524	40008547	19	-	27260156	SKES1	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.6091447190476567	[698]	[1111,1157,971,1024]	9	hSpCas9	negative selection	9098553
40008544	40008567	19	+	27260156	SKES1	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.3405293414447923	[154]	[153,204,293,129]	7	hSpCas9	negative selection	9098554
40007297	40007320	19	+	27260156	SKES1	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.31443778285722734	[217]	[287,198,334,251]	6	hSpCas9	negative selection	9098555
40007330	40007353	19	-	27260156	SKES1	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.05773310686973304	[566]	[505,798,626,446]	1	hSpCas9	negative selection	9162801
39998389	39998412	19	+	27260156	SKES1	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.5223873561359489	[360]	[381,408,752,487]	9	hSpCas9	negative selection	9162802
39998330	39998353	19	+	27260156	SKES1	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.03829442221312296	[878]	[874,902,938,713]	-1	hSpCas9	negative selection	9162803
40008524	40008547	19	-	27260156	TOV112D	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.46374583956432014	[698]	[904,1268,790,964]	8	hSpCas9	negative selection	9219804
40008544	40008567	19	+	27260156	TOV112D	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.3991315457215199	[154]	[151,359,196,144]	7	hSpCas9	negative selection	9219805
40007297	40007320	19	+	27260156	TOV112D	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.22937119058034883	[217]	[364,218,309,132]	4	hSpCas9	negative selection	9219806
40007330	40007353	19	-	27260156	TOV112D	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.19984445382502142	[566]	[782,647,574,612]	4	hSpCas9	negative selection	9284052
39998389	39998412	19	+	27260156	TOV112D	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.32454371474380045	[360]	[543,400,433,426]	6	hSpCas9	negative selection	9284053
39998330	39998353	19	+	27260156	TOV112D	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	-0.1196455307605725	[878]	[830,899,661,868]	-2	hSpCas9	negative selection	9284054
40008524	40008547	19	-	27260156	TC71	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.5069992107555177	[698]	[1049,1143,937,1135]	9	hSpCas9	negative selection	9341055
40008544	40008567	19	+	27260156	TC71	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.18816539854764458	[154]	[221,145,219,165]	5	hSpCas9	negative selection	9341056
40007297	40007320	19	+	27260156	TC71	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	0.44403938865712633	[217]	[378,303,357,221]	8	hSpCas9	negative selection	9341057
40007330	40007353	19	-	27260156	TC71	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.06169080998826848	[566]	[529,588,719,701]	1	hSpCas9	negative selection	9405303
39998389	39998412	19	+	27260156	TC71	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.3792679663687566	[360]	[424,589,508,489]	8	hSpCas9	negative selection	9405304
39998330	39998353	19	+	27260156	TC71	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.12041688505058978	[878]	[953,1062,1010,1073]	3	hSpCas9	negative selection	9405305
40008524	40008547	19	-	27260156	TC32	viability	CCCTTCCCTCATTACTATCCAGG	ZNF546	ENSG00000187187	0.7085745437077187	[698]	[934,967,1210,1200]	9	hSpCas9	negative selection	9462306
40008544	40008567	19	+	27260156	TC32	viability	GGGACAAGGAATTGGTTCACAGG	ZNF546	ENSG00000187187	0.6722040846101284	[154]	[266,115,301,284]	9	hSpCas9	negative selection	9462307
40007297	40007320	19	+	27260156	TC32	viability	GTCCATAGACCTCTCCCAAGAGG	ZNF546	ENSG00000187187	-0.010125098194317284	[217]	[181,213,246,160]	0	hSpCas9	negative selection	9462308
40007330	40007353	19	-	27260156	TC32	viability	AGTCCCTCTGCACAGCGTCCAGG	ZNF546	ENSG00000187187	0.2376888214005647	[566]	[471,432,873,847]	4	hSpCas9	negative selection	9526554
39998389	39998412	19	+	27260156	TC32	viability	TCTGCACTCACTTTCTATAATGG	ZNF546	ENSG00000187187	0.09687616975883512	[360]	[437,230,482,336]	1	hSpCas9	negative selection	9526555
39998330	39998353	19	+	27260156	TC32	viability	CAGGTGGACCCTCCTCTTCACGG	ZNF546	ENSG00000187187	0.012374872181324603	[878]	[724,683,995,983]	0	hSpCas9	negative selection	9526556
39998338	39998361	19	-	27869803	HPAFII	viability after 27 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.3762641300969468	[313]	[366,86,NaN]	3	hSpCas9	negative selection	9567792
39998339	39998362	19	-	27869803	HPAFII	viability after 27 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	0.9787089460615412	[251]	[391,151,NaN]	7	hSpCas9	negative selection	9567793
40006097	40006120	19	-	27869803	HPAFII	viability after 27 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.36670269475962153	[436]	[253,114,NaN]	-3	hSpCas9	negative selection	9567794
40008523	40008546	19	+	27869803	HPAFII	viability after 27 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.2872553436051518	[261]	[52,263,NaN]	2	hSpCas9	negative selection	9567795
40008524	40008547	19	+	27869803	HPAFII	viability after 27 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.42065892111591674	[358]	[376,148,NaN]	3	hSpCas9	negative selection	9567796
40013819	40013842	19	+	27869803	HPAFII	viability after 27 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	-0.08861677315209793	[56]	[25,29,NaN]	0	hSpCas9	negative selection	9567797
39998338	39998361	19	-	27869803	HPAFII	viability after 15 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.33199234297548297	[313]	[568,80,NaN]	-4	hSpCas9	negative selection	9650241
39998339	39998362	19	-	27869803	HPAFII	viability after 15 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	0.3874813583346049	[251]	[640,175,NaN]	4	hSpCas9	negative selection	9650242
40006097	40006120	19	-	27869803	HPAFII	viability after 15 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.5259070434236828	[436]	[541,191,NaN]	-5	hSpCas9	negative selection	9650243
40008523	40008546	19	+	27869803	HPAFII	viability after 15 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.17080504490205745	[261]	[176,403,NaN]	2	hSpCas9	negative selection	9650244
40008524	40008547	19	+	27869803	HPAFII	viability after 15 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.1514917291801572	[358]	[734,237,NaN]	1	hSpCas9	negative selection	9650245
40013819	40013842	19	+	27869803	HPAFII	viability after 15 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	-0.8947118890972598	[56]	[19,40,NaN]	-7	hSpCas9	negative selection	9650246
39998338	39998361	19	-	27869803	ASPC1	viability after 36 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.14550684359349694	[623]	[548,137,103]	1	hSpCas9	negative selection	9732690
39998339	39998362	19	-	27869803	ASPC1	viability after 36 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	0.5160417235964434	[623]	[314,319,298]	5	hSpCas9	negative selection	9732691
40006097	40006120	19	-	27869803	ASPC1	viability after 36 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	0.21273955877284145	[930]	[479,304,356]	2	hSpCas9	negative selection	9732692
40008523	40008546	19	+	27869803	ASPC1	viability after 36 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.36394748707756097	[546]	[458,258,82]	3	hSpCas9	negative selection	9732693
40008524	40008547	19	+	27869803	ASPC1	viability after 36 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	1.2528269075191618	[675]	[777,787,225]	9	hSpCas9	negative selection	9732694
40013819	40013842	19	+	27869803	ASPC1	viability after 36 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	1.3104975713021767	[170]	[312,177,6]	9	hSpCas9	negative selection	9732695
39998338	39998361	19	-	27869803	PATU8988S	viability after 35 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.8025124798663615	[483]	[333,345,NaN]	8	hSpCas9	negative selection	9815139
39998339	39998362	19	-	27869803	PATU8988S	viability after 35 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	0.2734701160025393	[549]	[155,379,NaN]	3	hSpCas9	negative selection	9815140
40006097	40006120	19	-	27869803	PATU8988S	viability after 35 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	0.37097449600320265	[832]	[374,492,NaN]	4	hSpCas9	negative selection	9815141
40008523	40008546	19	+	27869803	PATU8988S	viability after 35 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.31515047733777973	[449]	[218,231,NaN]	3	hSpCas9	negative selection	9815142
40008524	40008547	19	+	27869803	PATU8988S	viability after 35 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.3498100754355251	[676]	[337,356,NaN]	4	hSpCas9	negative selection	9815143
40013819	40013842	19	+	27869803	PATU8988S	viability after 35 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	-0.7693828958101601	[109]	[21,29,NaN]	-6	hSpCas9	negative selection	9815144
39998338	39998361	19	-	27869803	PATU8988S	viability after 31 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.8943227046535196	[483]	[363,351,NaN]	8	hSpCas9	negative selection	9897588
39998339	39998362	19	-	27869803	PATU8988S	viability after 31 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	0.045484646561557804	[549]	[96,390,NaN]	0	hSpCas9	negative selection	9897589
40006097	40006120	19	-	27869803	PATU8988S	viability after 31 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.21875393285667444	[832]	[196,397,NaN]	-2	hSpCas9	negative selection	9897590
40008523	40008546	19	+	27869803	PATU8988S	viability after 31 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.6039564569159971	[449]	[266,279,NaN]	7	hSpCas9	negative selection	9897591
40008524	40008547	19	+	27869803	PATU8988S	viability after 31 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.1112729080037616	[676]	[262,327,NaN]	1	hSpCas9	negative selection	9897592
40013819	40013842	19	+	27869803	PATU8988S	viability after 31 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	0.24328058909449135	[109]	[43,61,NaN]	3	hSpCas9	negative selection	9897593
39998338	39998361	19	-	27869803	HPAFII	viability after 35 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.7213695496458592	[313]	[318,197,NaN]	5	hSpCas9	negative selection	9980037
39998339	39998362	19	-	27869803	HPAFII	viability after 35 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	1.1136016503168513	[251]	[379,158,NaN]	7	hSpCas9	negative selection	9980038
40006097	40006120	19	-	27869803	HPAFII	viability after 35 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.28339328402717556	[436]	[201,158,NaN]	-2	hSpCas9	negative selection	9980039
40008523	40008546	19	+	27869803	HPAFII	viability after 35 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.06957443904161544	[261]	[46,242,NaN]	0	hSpCas9	negative selection	9980040
40008524	40008547	19	+	27869803	HPAFII	viability after 35 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.18138557627711238	[358]	[270,132,NaN]	1	hSpCas9	negative selection	9980041
40013819	40013842	19	+	27869803	HPAFII	viability after 35 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	0.16214873190257562	[56]	[20,44,NaN]	1	hSpCas9	negative selection	9980042
39998338	39998361	19	-	27869803	HPAFII	viability after 31 days	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.14623929373958627	[313]	[295,84,NaN]	1	hSpCas9	negative selection	10062486
39998339	39998362	19	-	27869803	HPAFII	viability after 31 days	TTTGGAGGCCCGTGAAGAGGAGG	ZNF546	ENSG00000187187	0.6579150922597166	[251]	[270,170,NaN]	5	hSpCas9	negative selection	10062487
40006097	40006120	19	-	27869803	HPAFII	viability after 31 days	GCACAGAATCCAGAGAAACCGGG	ZNF546	ENSG00000187187	-0.9273703947158141	[436]	[127,129,NaN]	-5	hSpCas9	negative selection	10062488
40008523	40008546	19	+	27869803	HPAFII	viability after 31 days	CCCTGGATAGTAATGAGGGAAGG	ZNF546	ENSG00000187187	0.5321398563186137	[261]	[47,391,NaN]	4	hSpCas9	negative selection	10062489
40008524	40008547	19	+	27869803	HPAFII	viability after 31 days	CCTGGATAGTAATGAGGGAAGGG	ZNF546	ENSG00000187187	0.3909398112866852	[358]	[379,137,NaN]	3	hSpCas9	negative selection	10062490
40013819	40013842	19	+	27869803	HPAFII	viability after 31 days	GAGACAAGAGAGACATCAGATGG	ZNF546	ENSG00000187187	-0.7279223951522664	[56]	[3,35,NaN]	-5	hSpCas9	negative selection	10062491
40008519	40008542	19	+	28162770	P31FUJ	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.664947737337671	[189]	[353]	7	hSpCas9	negative selection	10271264
40008476	40008499	19	-	28162770	P31FUJ	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-0.3410550950664022	[82]	[76]	-3	hSpCas9	negative selection	10271265
40006096	40006119	19	-	28162770	P31FUJ	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	-1.5842745749157565	[73]	[28]	-7	hSpCas9	negative selection	10271266
40007302	40007325	19	+	28162770	P31FUJ	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	0.9076790191354513	[43]	[96]	9	hSpCas9	negative selection	10271267
40007326	40007349	19	+	28162770	P31FUJ	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	-0.023539055021565544	[204]	[236]	0	hSpCas9	negative selection	10271268
39998314	39998337	19	+	28162770	P31FUJ	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.48380430211724856	[313]	[515]	5	hSpCas9	negative selection	10271269
39998338	39998361	19	-	28162770	P31FUJ	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.20875673044772747	[118]	[120]	-2	hSpCas9	negative selection	10271270
40006141	40006164	19	+	28162770	P31FUJ	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	1.3259287547335976	[147]	[435]	9	hSpCas9	negative selection	10271271
40006110	40006133	19	+	28162770	P31FUJ	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	-0.004309583541513007	[943]	[1105]	0	hSpCas9	negative selection	10271272
40006172	40006195	19	-	28162770	P31FUJ	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.2783027046089812	[707]	[1008]	3	hSpCas9	negative selection	10271273
40008519	40008542	19	+	28162770	TF1	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	NaN	[NaN]	[382]	1	hSpCas9	negative selection	10440630
40008476	40008499	19	-	28162770	TF1	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	NaN	[NaN]	[119]	1	hSpCas9	negative selection	10440631
40006096	40006119	19	-	28162770	TF1	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	NaN	[NaN]	[84]	1	hSpCas9	negative selection	10440632
40007302	40007325	19	+	28162770	TF1	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	NaN	[NaN]	[136]	1	hSpCas9	negative selection	10440633
40007326	40007349	19	+	28162770	TF1	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	NaN	[NaN]	[113]	1	hSpCas9	negative selection	10440634
39998314	39998337	19	+	28162770	TF1	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	NaN	[NaN]	[190]	1	hSpCas9	negative selection	10440635
39998338	39998361	19	-	28162770	TF1	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	NaN	[NaN]	[118]	1	hSpCas9	negative selection	10440636
40006141	40006164	19	+	28162770	TF1	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	NaN	[NaN]	[241]	1	hSpCas9	negative selection	10440637
40006110	40006133	19	+	28162770	TF1	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	NaN	[NaN]	[1087]	1	hSpCas9	negative selection	10440638
40006172	40006195	19	-	28162770	TF1	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	NaN	[NaN]	[1259]	1	hSpCas9	negative selection	10440639
40008519	40008542	19	+	28162770	SKM1	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.8218544917527191	[71]	[224]	7	hSpCas9	negative selection	10609996
40008476	40008499	19	-	28162770	SKM1	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-0.9044638582139788	[17]	[16]	-6	hSpCas9	negative selection	10609997
40006096	40006119	19	-	28162770	SKM1	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	-0.5000736031346429	[23]	[29]	-4	hSpCas9	negative selection	10609998
40007302	40007325	19	+	28162770	SKM1	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	0.614097416784668	[16]	[45]	6	hSpCas9	negative selection	10609999
40007326	40007349	19	+	28162770	SKM1	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	-0.2973397075686634	[56]	[81]	-3	hSpCas9	negative selection	10610000
39998314	39998337	19	+	28162770	SKM1	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.9038233385390002	[116]	[386]	8	hSpCas9	negative selection	10610001
39998338	39998361	19	-	28162770	SKM1	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.5851736834838679	[22]	[60]	5	hSpCas9	negative selection	10610002
40006141	40006164	19	+	28162770	SKM1	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	1.2324460860003708	[25]	[107]	9	hSpCas9	negative selection	10610003
40006110	40006133	19	+	28162770	SKM1	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	-0.241339334734475	[223]	[334]	-2	hSpCas9	negative selection	10610004
40006172	40006195	19	-	28162770	SKM1	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.3220086046695141	[180]	[399]	3	hSpCas9	negative selection	10610005
40008519	40008542	19	+	28162770	SKM1	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.8218544917527191	[71]	[224]	7	hSpCas9	negative selection	10779362
40008476	40008499	19	-	28162770	SKM1	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-0.9044638582139788	[17]	[16]	-6	hSpCas9	negative selection	10779363
40006096	40006119	19	-	28162770	SKM1	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	-0.5000736031346429	[23]	[29]	-4	hSpCas9	negative selection	10779364
40007302	40007325	19	+	28162770	SKM1	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	0.614097416784668	[16]	[45]	6	hSpCas9	negative selection	10779365
40007326	40007349	19	+	28162770	SKM1	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	-0.2973397075686634	[56]	[81]	-3	hSpCas9	negative selection	10779366
39998314	39998337	19	+	28162770	SKM1	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.9038233385390002	[116]	[386]	8	hSpCas9	negative selection	10779367
39998338	39998361	19	-	28162770	SKM1	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.5851736834838679	[22]	[60]	5	hSpCas9	negative selection	10779368
40006141	40006164	19	+	28162770	SKM1	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	1.2324460860003708	[25]	[107]	9	hSpCas9	negative selection	10779369
40006110	40006133	19	+	28162770	SKM1	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	-0.241339334734475	[223]	[334]	-2	hSpCas9	negative selection	10779370
40006172	40006195	19	-	28162770	SKM1	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.3220086046695141	[180]	[399]	3	hSpCas9	negative selection	10779371
40008519	40008542	19	+	28162770	PL21	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.0576005008420869	[286]	[129]	0	hSpCas9	negative selection	10948728
40008476	40008499	19	-	28162770	PL21	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	0.34769680290317795	[64]	[35]	3	hSpCas9	negative selection	10948729
40006096	40006119	19	-	28162770	PL21	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.27608846772261875	[73]	[38]	2	hSpCas9	negative selection	10948730
40007302	40007325	19	+	28162770	PL21	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	0.8782115196019578	[49]	[39]	7	hSpCas9	negative selection	10948731
40007326	40007349	19	+	28162770	PL21	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	-0.5570038616145163	[239]	[70]	-4	hSpCas9	negative selection	10948732
39998314	39998337	19	+	28162770	PL21	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	-0.04456296857221653	[390]	[164]	0	hSpCas9	negative selection	10948733
39998338	39998361	19	-	28162770	PL21	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-1.4354489593018038	[86]	[13]	-7	hSpCas9	negative selection	10948734
40006141	40006164	19	+	28162770	PL21	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	0.9522121010457345	[94]	[79]	7	hSpCas9	negative selection	10948735
40006110	40006133	19	+	28162770	PL21	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	0.21822197347277794	[554]	[280]	2	hSpCas9	negative selection	10948736
40006172	40006195	19	-	28162770	PL21	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.9750429842244939	[622]	[532]	7	hSpCas9	negative selection	10948737
40008519	40008542	19	+	28162770	P31FUJ	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.664947737337671	[189]	[353]	7	hSpCas9	negative selection	11118094
40008476	40008499	19	-	28162770	P31FUJ	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-0.3410550950664022	[82]	[76]	-3	hSpCas9	negative selection	11118095
40006096	40006119	19	-	28162770	P31FUJ	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	-1.5842745749157565	[73]	[28]	-7	hSpCas9	negative selection	11118096
40007302	40007325	19	+	28162770	P31FUJ	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	0.9076790191354513	[43]	[96]	9	hSpCas9	negative selection	11118097
40007326	40007349	19	+	28162770	P31FUJ	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	-0.023539055021565544	[204]	[236]	0	hSpCas9	negative selection	11118098
39998314	39998337	19	+	28162770	P31FUJ	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.48380430211724856	[313]	[515]	5	hSpCas9	negative selection	11118099
39998338	39998361	19	-	28162770	P31FUJ	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.20875673044772747	[118]	[120]	-2	hSpCas9	negative selection	11118100
40006141	40006164	19	+	28162770	P31FUJ	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	1.3259287547335976	[147]	[435]	9	hSpCas9	negative selection	11118101
40006110	40006133	19	+	28162770	P31FUJ	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	-0.004309583541513007	[943]	[1105]	0	hSpCas9	negative selection	11118102
40006172	40006195	19	-	28162770	P31FUJ	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.2783027046089812	[707]	[1008]	3	hSpCas9	negative selection	11118103
40008519	40008542	19	+	28162770	OCIAML5	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.8017050877758104	[115]	[364]	7	hSpCas9	negative selection	11287460
40008476	40008499	19	-	28162770	OCIAML5	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-0.21463665024870549	[62]	[97]	-1	hSpCas9	negative selection	11287461
40006096	40006119	19	-	28162770	OCIAML5	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	1.1072914446386573	[26]	[104]	8	hSpCas9	negative selection	11287462
40007302	40007325	19	+	28162770	OCIAML5	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	3.526445052389733	[9]	[207]	9	hSpCas9	negative selection	11287463
40007326	40007349	19	+	28162770	OCIAML5	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	-0.35403970691412157	[113]	[160]	-3	hSpCas9	negative selection	11287464
39998314	39998337	19	+	28162770	OCIAML5	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.8087273428168054	[209]	[663]	7	hSpCas9	negative selection	11287465
39998338	39998361	19	-	28162770	OCIAML5	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.8406097471574125	[42]	[138]	7	hSpCas9	negative selection	11287466
40006141	40006164	19	+	28162770	OCIAML5	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	0.8848990233022092	[98]	[329]	7	hSpCas9	negative selection	11287467
40006110	40006133	19	+	28162770	OCIAML5	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	0.23499779088073258	[425]	[904]	2	hSpCas9	negative selection	11287468
40006172	40006195	19	-	28162770	OCIAML5	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.9502030620338242	[405]	[1415]	8	hSpCas9	negative selection	11287469
40008519	40008542	19	+	28162770	EOL1	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.1956758594506649	[473]	[285]	1	hSpCas9	negative selection	11456826
40008476	40008499	19	-	28162770	EOL1	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-1.2933572587735993	[106]	[22]	-7	hSpCas9	negative selection	11456827
40006096	40006119	19	-	28162770	EOL1	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	-0.9887405952361346	[112]	[29]	-6	hSpCas9	negative selection	11456828
40007302	40007325	19	+	28162770	EOL1	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	-1.414254141881224	[85]	[16]	-7	hSpCas9	negative selection	11456829
40007326	40007349	19	+	28162770	EOL1	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	-0.008338032570928577	[398]	[208]	0	hSpCas9	negative selection	11456830
39998314	39998337	19	+	28162770	EOL1	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.3903457919918436	[739]	[510]	3	hSpCas9	negative selection	11456831
39998338	39998361	19	-	28162770	EOL1	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	0.10011933615398894	[84]	[47]	0	hSpCas9	negative selection	11456832
40006141	40006164	19	+	28162770	EOL1	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	-0.4321457414775044	[209]	[81]	-3	hSpCas9	negative selection	11456833
40006110	40006133	19	+	28162770	EOL1	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	-0.4667500066390382	[883]	[336]	-3	hSpCas9	negative selection	11456834
40006172	40006195	19	-	28162770	EOL1	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.9056887443192188	[769]	[759]	7	hSpCas9	negative selection	11456835
40008519	40008542	19	+	28162770	MOLM13	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.17478412182297032	[445]	[363]	1	hSpCas9	negative selection	11626192
40008476	40008499	19	-	28162770	MOLM13	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-1.7079604538548387	[121]	[26]	-7	hSpCas9	negative selection	11626193
40006096	40006119	19	-	28162770	MOLM13	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	-0.5451667712808677	[110]	[54]	-3	hSpCas9	negative selection	11626194
40007302	40007325	19	+	28162770	MOLM13	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	0.44279840058174824	[57]	[56]	3	hSpCas9	negative selection	11626195
40007326	40007349	19	+	28162770	MOLM13	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	-0.06359423716569479	[330]	[228]	0	hSpCas9	negative selection	11626196
39998314	39998337	19	+	28162770	MOLM13	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.4625950818750659	[545]	[543]	3	hSpCas9	negative selection	11626197
39998338	39998361	19	-	28162770	MOLM13	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.8337663183165225	[105]	[42]	-4	hSpCas9	negative selection	11626198
40006141	40006164	19	+	28162770	MOLM13	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	1.0766986242201027	[119]	[182]	7	hSpCas9	negative selection	11626199
40006110	40006133	19	+	28162770	MOLM13	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	0.6197239260039951	[855]	[950]	4	hSpCas9	negative selection	11626200
40006172	40006195	19	-	28162770	MOLM13	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.5112707279299635	[949]	[978]	4	hSpCas9	negative selection	11626201
40008519	40008542	19	+	28162770	HEL	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.532062600844242	[324]	[300]	4	hSpCas9	negative selection	11795558
40008476	40008499	19	-	28162770	HEL	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-2.9422236687208	[83]	[6]	-8	hSpCas9	negative selection	11795559
40006096	40006119	19	-	28162770	HEL	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.9308642187969811	[94]	[115]	7	hSpCas9	negative selection	11795560
40007302	40007325	19	+	28162770	HEL	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	1.1546378705317897	[53]	[76]	8	hSpCas9	negative selection	11795561
40007326	40007349	19	+	28162770	HEL	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	0.6838147750032725	[276]	[284]	6	hSpCas9	negative selection	11795562
39998314	39998337	19	+	28162770	HEL	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	1.0814275993438462	[483]	[655]	8	hSpCas9	negative selection	11795563
39998338	39998361	19	-	28162770	HEL	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.2983674789460746	[95]	[49]	-2	hSpCas9	negative selection	11795564
40006141	40006164	19	+	28162770	HEL	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	1.0674265013129203	[148]	[199]	8	hSpCas9	negative selection	11795565
40006110	40006133	19	+	28162770	HEL	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	-0.5725291549027096	[807]	[347]	-4	hSpCas9	negative selection	11795566
40006172	40006195	19	-	28162770	HEL	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.43341501291133055	[695]	[601]	3	hSpCas9	negative selection	11795567
40008519	40008542	19	+	28162770	MV411	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.48350490901629983	[269]	[317]	4	hSpCas9	negative selection	11964924
40008476	40008499	19	-	28162770	MV411	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	1.0645734936329647	[62]	[110]	8	hSpCas9	negative selection	11964925
40006096	40006119	19	-	28162770	MV411	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	1.0793147919744484	[49]	[88]	8	hSpCas9	negative selection	11964926
40007302	40007325	19	+	28162770	MV411	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	1.2067955662854293	[71]	[139]	9	hSpCas9	negative selection	11964927
40007326	40007349	19	+	28162770	MV411	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	0.03413300227428617	[210]	[181]	0	hSpCas9	negative selection	11964928
39998314	39998337	19	+	28162770	MV411	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	-0.7249502180093648	[413]	[210]	-5	hSpCas9	negative selection	11964929
39998338	39998361	19	-	28162770	MV411	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	1.142467991181233	[56]	[105]	8	hSpCas9	negative selection	11964930
40006141	40006164	19	+	28162770	MV411	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	-0.6091982740460475	[133]	[73]	-4	hSpCas9	negative selection	11964931
40006110	40006133	19	+	28162770	MV411	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	-0.24405200893394174	[619]	[440]	-2	hSpCas9	negative selection	11964932
40006172	40006195	19	-	28162770	MV411	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.9647073436080618	[530]	[872]	8	hSpCas9	negative selection	11964933
40008519	40008542	19	+	28162770	MONOMAC1	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	-0.16158801105526366	[200]	[205]	-1	hSpCas9	negative selection	12134290
40008476	40008499	19	-	28162770	MONOMAC1	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	1.1458508664634548	[40]	[103]	8	hSpCas9	negative selection	12134291
40006096	40006119	19	-	28162770	MONOMAC1	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.006496547025578225	[32]	[37]	0	hSpCas9	negative selection	12134292
40007302	40007325	19	+	28162770	MONOMAC1	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	-0.48082981306014494	[27]	[22]	-4	hSpCas9	negative selection	12134293
40007326	40007349	19	+	28162770	MONOMAC1	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	0.07166630886093217	[126]	[152]	0	hSpCas9	negative selection	12134294
39998314	39998337	19	+	28162770	MONOMAC1	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	-0.34670169843540266	[273]	[246]	-3	hSpCas9	negative selection	12134295
39998338	39998361	19	-	28162770	MONOMAC1	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.05118598059609902	[46]	[51]	0	hSpCas9	negative selection	12134296
40006141	40006164	19	+	28162770	MONOMAC1	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	1.927658900389761	[71]	[313]	9	hSpCas9	negative selection	12134297
40006110	40006133	19	+	28162770	MONOMAC1	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	0.72027587063818	[376]	[711]	7	hSpCas9	negative selection	12134298
40006172	40006195	19	-	28162770	MONOMAC1	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.2247354862480182	[373]	[500]	2	hSpCas9	negative selection	12134299
40008519	40008542	19	+	28162770	OCIAML2	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.4511450074523364	[44]	[340]	4	hSpCas9	negative selection	12303656
40008476	40008499	19	-	28162770	OCIAML2	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	0.18472200337039313	[9]	[62]	1	hSpCas9	negative selection	12303657
40006096	40006119	19	-	28162770	OCIAML2	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	0.630908201219901	[11]	[102]	6	hSpCas9	negative selection	12303658
40007302	40007325	19	+	28162770	OCIAML2	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	-0.7579117773226323	[17]	[58]	-5	hSpCas9	negative selection	12303659
40007326	40007349	19	+	28162770	OCIAML2	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	0.07369069098164904	[41]	[244]	0	hSpCas9	negative selection	12303660
39998314	39998337	19	+	28162770	OCIAML2	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.9888017933951361	[67]	[747]	8	hSpCas9	negative selection	12303661
39998338	39998361	19	-	28162770	OCIAML2	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	-0.21189555684199313	[13]	[66]	-2	hSpCas9	negative selection	12303662
40006141	40006164	19	+	28162770	OCIAML2	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	1.9279195512481135	[10]	[231]	9	hSpCas9	negative selection	12303663
40006110	40006133	19	+	28162770	OCIAML2	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	0.3299887653195668	[91]	[640]	3	hSpCas9	negative selection	12303664
40006172	40006195	19	-	28162770	OCIAML2	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.9665260800214028	[88]	[963]	8	hSpCas9	negative selection	12303665
40008519	40008542	19	+	28162770	OCIAML3	viability	AGAGCCCTGGATAGTAATGAGGG	ZNF546	ENSG00000187187	0.5714577129274492	[71]	[322]	5	hSpCas9	negative selection	12473022
40008476	40008499	19	-	28162770	OCIAML3	viability	AATCACATCTGGCTTAGGAATGG	ZNF546	ENSG00000187187	-0.7639326417664757	[26]	[47]	-5	hSpCas9	negative selection	12473023
40006096	40006119	19	-	28162770	OCIAML3	viability	CACAGAATCCAGAGAAACCGGGG	ZNF546	ENSG00000187187	-0.47853042290422737	[41]	[90]	-4	hSpCas9	negative selection	12473024
40007302	40007325	19	+	28162770	OCIAML3	viability	TAGACCTCTCCCAAGAGGAGTGG	ZNF546	ENSG00000187187	0.9444122744599626	[20]	[121]	7	hSpCas9	negative selection	12473025
40007326	40007349	19	+	28162770	OCIAML3	viability	AGTGCCTGGACGCTGTGCAGAGG	ZNF546	ENSG00000187187	-0.7960514162688086	[87]	[152]	-5	hSpCas9	negative selection	12473026
39998314	39998337	19	+	28162770	OCIAML3	viability	TGAACAATGGACCATGCAGGTGG	ZNF546	ENSG00000187187	0.4455207238624743	[98]	[406]	4	hSpCas9	negative selection	12473027
39998338	39998361	19	-	28162770	OCIAML3	viability	TTGGAGGCCCGTGAAGAGGAGGG	ZNF546	ENSG00000187187	1.034023582288879	[32]	[203]	8	hSpCas9	negative selection	12473028
40006141	40006164	19	+	28162770	OCIAML3	viability	GGAGAACTGACAAGTTCTTGTGG	ZNF546	ENSG00000187187	0.5686125604949157	[43]	[196]	5	hSpCas9	negative selection	12473029
40006110	40006133	19	+	28162770	OCIAML3	viability	GATTCTGTGCTTCTCCATGGAGG	ZNF546	ENSG00000187187	0.33199177823205983	[159]	[607]	3	hSpCas9	negative selection	12473030
40006172	40006195	19	-	28162770	OCIAML3	viability	ACACAAACTTACATTGGCCATGG	ZNF546	ENSG00000187187	0.9639878127967234	[134]	[794]	8	hSpCas9	negative selection	12473031