Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:442319
• Symbol:ZNF727
• Description:zinc finger protein 727

DataSource: http://genomecrispr.dkfz.de/#!/results/ZNF727

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
64069559	64069582	7	+	26472758	Jiyoye	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	-0.32306434947201934	[213]	[128]	-2	hSpCas9	negative selection	189553
64078176	64078199	7	-	26472758	Jiyoye	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	1.5683301733204538	[109]	[245]	8	hSpCas9	negative selection	189554
64068887	64068910	7	+	26472758	Jiyoye	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	1.6709295154867414	[166]	[400]	8	hSpCas9	negative selection	189555
64077388	64077411	7	+	26472758	Jiyoye	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	1.0861813721421676	[192]	[308]	7	hSpCas9	negative selection	189556
64078511	64078534	7	-	26472758	Jiyoye	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	0.9361038473127017	[69]	[100]	6	hSpCas9	negative selection	189557
64077400	64077423	7	-	26472758	Jiyoye	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	0.27956118492152526	[188]	[172]	2	hSpCas9	negative selection	189558
64077768	64077791	7	-	26472758	Jiyoye	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	1.0186100935882205	[143]	[219]	6	hSpCas9	negative selection	189559
64069588	64069611	7	+	26472758	Jiyoye	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-0.11067292335674572	[62]	[43]	-1	hSpCas9	negative selection	189560
64078428	64078451	7	-	26472758	Jiyoye	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	-0.7039366433526606	[714]	[330]	-5	hSpCas9	negative selection	189561
64078098	64078121	7	-	26472758	Jiyoye	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-0.6148509248241256	[263]	[129]	-4	hSpCas9	negative selection	189562
64069550	64069573	7	+	26472758	Jiyoye	viability	TGGAGCAAAGAAAAGAGCCTTGG	ZNF727	ENSG00000214652	3.5327062635897324	[10]	[95]	9	hSpCas9	negative selection	189612
64069559	64069582	7	+	26472758	KBM7	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.7935166564968752	[625,530]	[737,229]	8	hSpCas9	negative selection	380671
64078176	64078199	7	-	26472758	KBM7	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	0.7612253703152808	[801,938]	[566,823]	8	hSpCas9	negative selection	380672
64068887	64068910	7	+	26472758	KBM7	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.504827533411681	[1426,1379]	[1036,851]	5	hSpCas9	negative selection	380673
64077388	64077411	7	+	26472758	KBM7	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	0.11916440555564245	[775,637]	[430,294]	1	hSpCas9	negative selection	380674
64078511	64078534	7	-	26472758	KBM7	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	0.6021496696287059	[360,180]	[304,82]	6	hSpCas9	negative selection	380675
64077400	64077423	7	-	26472758	KBM7	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	-0.2696748121998251	[684,767]	[297,275]	-3	hSpCas9	negative selection	380676
64077768	64077791	7	-	26472758	KBM7	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	0.2304472035059031	[1241,894]	[544,615]	2	hSpCas9	negative selection	380677
64069588	64069611	7	+	26472758	KBM7	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-0.4254729106973113	[272,279]	[70,120]	-4	hSpCas9	negative selection	380678
64078428	64078451	7	-	26472758	KBM7	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.6038241223520637	[1950,1791]	[1356,1320]	6	hSpCas9	negative selection	380679
64078098	64078121	7	-	26472758	KBM7	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-0.9547008301147164	[1211,1081]	[296,260]	-6	hSpCas9	negative selection	380680
64069550	64069573	7	+	26472758	KBM7	viability	TGGAGCAAAGAAAAGAGCCTTGG	ZNF727	ENSG00000214652	-0.0910876185487377	[235,180]	[114,69]	-1	hSpCas9	negative selection	380730
64069559	64069582	7	+	26472758	Raji	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	-0.3465729531975468	[262]	[47]	-3	hSpCas9	negative selection	571789
64078176	64078199	7	-	26472758	Raji	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	1.1073835353735997	[387]	[193]	8	hSpCas9	negative selection	571790
64068887	64068910	7	+	26472758	Raji	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	1.1199287886927132	[457]	[230]	8	hSpCas9	negative selection	571791
64077388	64077411	7	+	26472758	Raji	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	-0.4342751811266964	[360]	[61]	-4	hSpCas9	negative selection	571792
64078511	64078534	7	-	26472758	Raji	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	1.3022952202879403	[158]	[90]	9	hSpCas9	negative selection	571793
64077400	64077423	7	-	26472758	Raji	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	0.6479519167363021	[252]	[91]	6	hSpCas9	negative selection	571794
64077768	64077791	7	-	26472758	Raji	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	-0.3235955077742656	[727]	[134]	-3	hSpCas9	negative selection	571795
64069588	64069611	7	+	26472758	Raji	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-0.6909826034567501	[159]	[22]	-5	hSpCas9	negative selection	571796
64078428	64078451	7	-	26472758	Raji	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.5707165916932246	[939]	[323]	5	hSpCas9	negative selection	571797
64078098	64078121	7	-	26472758	Raji	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-0.22978443757405564	[570]	[112]	-2	hSpCas9	negative selection	571798
64069550	64069573	7	+	26472758	Raji	viability	TGGAGCAAAGAAAAGAGCCTTGG	ZNF727	ENSG00000214652	0.8007221971395477	[93]	[37]	7	hSpCas9	negative selection	571848
64069559	64069582	7	+	26472758	K562	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.8942660321998145	[470]	[738]	7	hSpCas9	negative selection	762907
64078176	64078199	7	-	26472758	K562	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	1.2282138558099658	[760]	[1504]	9	hSpCas9	negative selection	762908
64068887	64068910	7	+	26472758	K562	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	1.0401122109900756	[904]	[1570]	8	hSpCas9	negative selection	762909
64077388	64077411	7	+	26472758	K562	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	0.7215171950775423	[545]	[759]	6	hSpCas9	negative selection	762910
64078511	64078534	7	-	26472758	K562	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	1.515627064945941	[219]	[530]	9	hSpCas9	negative selection	762911
64077400	64077423	7	-	26472758	K562	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	-0.3154717510978766	[655]	[444]	-2	hSpCas9	negative selection	762912
64077768	64077791	7	-	26472758	K562	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	0.9886848572757725	[1024]	[1716]	8	hSpCas9	negative selection	762913
64069588	64069611	7	+	26472758	K562	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-0.7261374944410711	[193]	[98]	-4	hSpCas9	negative selection	762914
64078428	64078451	7	-	26472758	K562	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.7140439629531179	[1717]	[2378]	6	hSpCas9	negative selection	762915
64078098	64078121	7	-	26472758	K562	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-0.7749866715061462	[972]	[479]	-4	hSpCas9	negative selection	762916
64069550	64069573	7	+	26472758	K562	viability	TGGAGCAAAGAAAAGAGCCTTGG	ZNF727	ENSG00000214652	0.2981899841074275	[157]	[163]	2	hSpCas9	negative selection	762966
64077390	64077413	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGAAAGACTACCAACGTGTGGG	ZNF727	ENSG00000214652	-0.33338615372906394	[3,2]	[2,1]	-5	hSpCas9	positive selection	3035276
64077774	64077797	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTTCTCTTGTGTTTAGTAAGGG	ZNF727	ENSG00000214652	0.1524245503231576	[5,5]	[5,5]	3	hSpCas9	positive selection	3035277
64077400	64077423	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	-0.004379624677689153	[4,4]	[3,4]	0	hSpCas9	positive selection	3035278
64069560	64069583	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.0492918252338333	[4,4]	[4,3]	1	hSpCas9	positive selection	3035279
64077390	64077413	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGAAAGACTACCAACGTGTGGG	ZNF727	ENSG00000214652	0.297556106520197	[3,3]	[3,2]	5	hSpCas9	positive selection	3103134
64077774	64077797	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTTCTCTTGTGTTTAGTAAGGG	ZNF727	ENSG00000214652	-0.1429368609351354	[5,5]	[5,1]	-2	hSpCas9	positive selection	3103135
64077400	64077423	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	-0.024132062516867447	[4,4]	[3,2]	0	hSpCas9	positive selection	3103136
64069560	64069583	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.1725925669558171	[4,4]	[5,2]	3	hSpCas9	positive selection	3103137
64069559	64069582		+	24336571	A375	resistance to PLX after 7 days	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	-0.20233900923766324	[6,6]	[5,5]	-6	hSpCas9	positive selection	3158124
64068886	64068909		+	24336571	A375	resistance to PLX after 7 days	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.0809064039251437	[50,42]	[50,47]	3	hSpCas9	positive selection	3158125
64069567	64069590		-	24336571	A375	resistance to PLX after 7 days	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	-0.15670867181128356	[20,13]	[14,15]	-5	hSpCas9	positive selection	3158126
64069559	64069582		+	24336571	A375	resistance to PLX after 14 days	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	-0.2956728378332648	[11,6]	[2,2]	-3	hSpCas9	positive selection	3215917
64068886	64068909		+	24336571	A375	resistance to PLX after 14 days	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	-0.31087918900883693	[54,43]	[17,18]	-4	hSpCas9	positive selection	3215918
64069567	64069590		-	24336571	A375	resistance to PLX after 14 days	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	-1.214714680174799	[23,11]	[2,3]	-9	hSpCas9	positive selection	3215919
64069559	64069582		+	24336571	A375	viability after 7 days	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.33454141902149015	[5]	[6,6]	5	hSpCas9	negative selection	3273710
64068886	64068909		+	24336571	A375	viability after 7 days	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.5390205021198562	[33]	[50,42]	7	hSpCas9	negative selection	3273711
64069567	64069590		-	24336571	A375	viability after 7 days	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	-0.5037910110414365	[25]	[20,13]	-6	hSpCas9	negative selection	3273712
64069559	64069582		+	24336571	A375	viability after 14 days	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.6859890796669926	[5]	[11,6]	8	hSpCas9	negative selection	3331503
64068886	64068909		+	24336571	A375	viability after 14 days	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.6400380441001445	[33]	[54,43]	7	hSpCas9	negative selection	3331504
64069567	64069590		-	24336571	A375	viability after 14 days	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	-0.419754658165224	[25]	[23,11]	-5	hSpCas9	negative selection	3331505
64077480	64077503	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	1.0609289986423316	[219,219]	[2,2]	5	hSpCas9	positive selection	3403500
64077370	64077393	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.21293209208738176	[131,131]	[0,0]	1	hSpCas9	positive selection	3403501
64069004	64069027	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	1.8310614567437373	[42,42]	[0,0]	7	hSpCas9	positive selection	3403502
64077389	64077412	7	+	26780180	HT29	viability (Avana library 4 designs)	AAGAAAGACTACCAACGTGTGGG	ZNF727	ENSG00000214652	0.977286039185774	[]	[]	4	hSpCas9	negative selection	3474632
64077774	64077797	7	-	26780180	HT29	viability (Avana library 4 designs)	ATTTCTCTTGTGTTTAGTAAGGG	ZNF727	ENSG00000214652	-0.132773894565326	[]	[]	-2	hSpCas9	negative selection	3474633
64077400	64077423	7	-	26780180	HT29	viability (Avana library 4 designs)	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	0.416791891937828	[]	[]	1	hSpCas9	negative selection	3474634
64069559	64069582	7	+	26780180	HT29	viability (Avana library 4 designs)	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.508853480923441	[]	[]	2	hSpCas9	negative selection	3474635
64077400	64077423	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	-5.53789827615129	[]	[]	-6	hSpCas9	negative selection	3583017
64069559	64069582	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	5.56305971046282	[]	[]	8	hSpCas9	negative selection	3583018
64077774	64077797	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATTTCTCTTGTGTTTAGTAAGGG	ZNF727	ENSG00000214652	-13.0536827721899	[]	[]	-8	hSpCas9	negative selection	3583019
64077389	64077412	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAGAAAGACTACCAACGTGTGGG	ZNF727	ENSG00000214652	-1.9971892158311	[]	[]	-2	hSpCas9	negative selection	3583020
64068887	64068910	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	5.13527665475389	[]	[]	8	hSpCas9	negative selection	3583021
64077400	64077423	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	4.71238335283202	[]	[]	7	hSpCas9	negative selection	3583022
64077400	64077423	7	-	26780180	A375	viability (Avana lentiGuide)	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	4.55790285905504	[]	[]	4	hSpCas9	negative selection	3691676
64069559	64069582	7	+	26780180	A375	viability (Avana lentiGuide)	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	-0.315266169336244	[]	[]	0	hSpCas9	negative selection	3691677
64077774	64077797	7	-	26780180	A375	viability (Avana lentiGuide)	ATTTCTCTTGTGTTTAGTAAGGG	ZNF727	ENSG00000214652	-4.96076619179501	[]	[]	-8	hSpCas9	negative selection	3691678
64077389	64077412	7	+	26780180	A375	viability (Avana lentiGuide)	AAGAAAGACTACCAACGTGTGGG	ZNF727	ENSG00000214652	14.482767281831	[]	[]	8	hSpCas9	negative selection	3691679
64068887	64068910	7	+	26780180	A375	viability (Avana lentiGuide)	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	-5.85309707518976	[]	[]	-8	hSpCas9	negative selection	3691680
64077400	64077423	7	+	26780180	A375	viability (Avana lentiGuide)	CCAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	12.6233014056905	[]	[]	7	hSpCas9	negative selection	3691681
64077400	64077423	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	-0.3213241161036006	[5]	[4,3]	-5	hSpCas9	positive selection	3800283
64069559	64069582	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.21241233166486825	[5]	[7,5]	6	hSpCas9	positive selection	3800284
64077774	64077797	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTTCTCTTGTGTTTAGTAAGGG	ZNF727	ENSG00000214652	-0.6446205566755975	[10]	[6,5]	-7	hSpCas9	positive selection	3800285
64077389	64077412	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGAAAGACTACCAACGTGTGGG	ZNF727	ENSG00000214652	-0.0789741175212936	[5]	[5,4]	-1	hSpCas9	positive selection	3800286
64068887	64068910	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.246485097393623	[6]	[7,7]	7	hSpCas9	positive selection	3800287
64077400	64077423	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	0.1471418787361909	[4]	[4,5]	4	hSpCas9	positive selection	3800288
64077400	64077423	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	0.15961616270497941	[6]	[6,6]	4	hSpCas9	positive selection	3908890
64069559	64069582	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	-0.09111612312900996	[6]	[5,4]	-1	hSpCas9	positive selection	3908891
64077774	64077797	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTTCTCTTGTGTTTAGTAAGGG	ZNF727	ENSG00000214652	0.42639528645647257	[6]	[8,7]	9	hSpCas9	positive selection	3908892
64077389	64077412	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGAAAGACTACCAACGTGTGGG	ZNF727	ENSG00000214652	-0.30387933470817163	[4]	[2,2]	-4	hSpCas9	positive selection	3908893
64068887	64068910	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.38720595238157185	[6]	[7,6]	9	hSpCas9	positive selection	3908894
64077400	64077423	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	-0.48517782468390125	[5]	[3,2]	-6	hSpCas9	positive selection	3908895
64069559	64069582	7	+	26780180	A375	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	1.14796248645579	[]	[]	6	hSpCas9	negative selection	4016846
64077480	64077503	7	-	26780180	A375	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	1.37851989889582	[]	[]	7	hSpCas9	negative selection	4016847
64069004	64069027	7	-	26780180	A375	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.732844323718696	[]	[]	2	hSpCas9	negative selection	4016848
64077370	64077393	7	-	26780180	A375	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	1.42447098601172	[]	[]	7	hSpCas9	negative selection	4016849
64068886	64068909	7	+	26780180	A375	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	1.19815525560136	[]	[]	6	hSpCas9	negative selection	4016850
64069567	64069590	7	-	26780180	A375	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	-0.0528052879716795	[]	[]	-2	hSpCas9	negative selection	4016851
64069559	64069582	7	+	26780180	HT29	viability (GeCKOv2 library)	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	1.61192496712641	[]	[]	8	hSpCas9	negative selection	4124812
64077480	64077503	7	-	26780180	HT29	viability (GeCKOv2 library)	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	1.79484610950369	[]	[]	8	hSpCas9	negative selection	4124813
64069004	64069027	7	-	26780180	HT29	viability (GeCKOv2 library)	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	1.22556908348649	[]	[]	6	hSpCas9	negative selection	4124814
64077370	64077393	7	-	26780180	HT29	viability (GeCKOv2 library)	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	1.09138108444646	[]	[]	5	hSpCas9	negative selection	4124815
64068886	64068909	7	+	26780180	HT29	viability (GeCKOv2 library)	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	1.51307796920216	[]	[]	7	hSpCas9	negative selection	4124816
64069567	64069590	7	-	26780180	HT29	viability (GeCKOv2 library)	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	-0.447099984528278	[]	[]	-8	hSpCas9	negative selection	4124817
64069559	64069582	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	-0.1277030480452755	[2]	[1,1]	-3	hSpCas9	positive selection	4185346
64068886	64068909	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.18734666925010907	[5]	[3,4]	5	hSpCas9	positive selection	4185347
64069567	64069590	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	-0.5466883166952611	[4]	[1,1]	-9	hSpCas9	positive selection	4185348
64069559	64069582	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	-0.4216052397717217	[3]	[0,1,0,0]	-6	hSpCas9	positive selection	4249368
64068886	64068909	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	1.019598773209632	[5]	[5,5,4,4]	7	hSpCas9	positive selection	4249369
64069567	64069590	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	1.128145034809369	[4]	[4,3,1,5]	8	hSpCas9	positive selection	4249370
64068886	64068909	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	-0.10007187313334899	[3]	[2,1]	-2	hSpCas9	positive selection	4310249
64069559	64069582	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.5914170690992037	[1]	[0,3]	9	hSpCas9	positive selection	4310250
64069567	64069590	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.6312402217061561	[3]	[4,4]	9	hSpCas9	positive selection	4310251
64077480	64077503	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	0.03171984155780952	[3]	[3,1]	0	hSpCas9	positive selection	4374496
64077370	64077393	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.1947061378346543	[2]	[3,1]	4	hSpCas9	positive selection	4374497
64069004	64069027	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	-0.5328894745103459	[1]	[1,0]	-8	hSpCas9	positive selection	4374498
64068996	64069018	7	+	27760321	OCIAML3	viability	TACGGAAACCTGTTCTCCTTGG	ZNF727	ENSG00000214652	0.9036733700292559	[341,236]	[399,442]	9	hSpCas9	negative selection	4457716
64069560	64069582	7	+	27760321	OCIAML3	viability	AAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.5163418565779474	[581,472]	[540,646]	6	hSpCas9	negative selection	4457717
64069589	64069611	7	+	27760321	OCIAML3	viability	AGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-1.2614552228624287	[527,423]	[77,253]	-8	hSpCas9	negative selection	4457718
64077401	64077423	7	+	27760321	OCIAML3	viability	CAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	-0.4768556664421912	[508,437]	[250,283]	-5	hSpCas9	negative selection	4457719
64077468	64077490	7	-	27760321	OCIAML3	viability	TATTGACAGGTTTTGCTACGGG	ZNF727	ENSG00000214652	0.2568163696992103	[248,237]	[226,228]	3	hSpCas9	negative selection	4457720
64068996	64069018	7	+	27760321	OCIAML2	viability	TACGGAAACCTGTTCTCCTTGG	ZNF727	ENSG00000214652	0.5560525995399326	[341,236]	[250,457]	7	hSpCas9	negative selection	4541179
64069560	64069582	7	+	27760321	OCIAML2	viability	AAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.494706595062489	[581,472]	[513,708]	6	hSpCas9	negative selection	4541180
64069589	64069611	7	+	27760321	OCIAML2	viability	AGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-1.4924853133936897	[527,423]	[145,122]	-8	hSpCas9	negative selection	4541181
64077401	64077423	7	+	27760321	OCIAML2	viability	CAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	-0.5761904822806627	[508,437]	[187,345]	-6	hSpCas9	negative selection	4541182
64077468	64077490	7	-	27760321	OCIAML2	viability	TATTGACAGGTTTTGCTACGGG	ZNF727	ENSG00000214652	-0.03332782990573413	[248,237]	[206,173]	0	hSpCas9	negative selection	4541183
64068996	64069018	7	+	27760321	MV411	viability	TACGGAAACCTGTTCTCCTTGG	ZNF727	ENSG00000214652	-0.9411013867729949	[341,236]	[33,194]	-6	hSpCas9	negative selection	4624642
64069560	64069582	7	+	27760321	MV411	viability	AAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.19830228193842192	[581,472]	[292,553]	1	hSpCas9	negative selection	4624643
64069589	64069611	7	+	27760321	MV411	viability	AGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-1.9338645990794088	[527,423]	[14,181]	-8	hSpCas9	negative selection	4624644
64077401	64077423	7	+	27760321	MV411	viability	CAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	0.4065855177953829	[508,437]	[406,421]	3	hSpCas9	negative selection	4624645
64077468	64077490	7	-	27760321	MV411	viability	TATTGACAGGTTTTGCTACGGG	ZNF727	ENSG00000214652	1.642859433360748	[248,237]	[639,295]	9	hSpCas9	negative selection	4624646
64068996	64069018	7	+	27760321	HL60	viability	TACGGAAACCTGTTCTCCTTGG	ZNF727	ENSG00000214652	0.1995649895834506	[341,236]	[331,200]	2	hSpCas9	negative selection	4708105
64069560	64069582	7	+	27760321	HL60	viability	AAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.08228830727278258	[581,472]	[447,459]	1	hSpCas9	negative selection	4708106
64069589	64069611	7	+	27760321	HL60	viability	AGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-1.3156664560466305	[527,423]	[165,143]	-8	hSpCas9	negative selection	4708107
64077401	64077423	7	+	27760321	HL60	viability	CAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	0.4711366032544546	[508,437]	[422,652]	6	hSpCas9	negative selection	4708108
64077468	64077490	7	-	27760321	HL60	viability	TATTGACAGGTTTTGCTACGGG	ZNF727	ENSG00000214652	0.25871307598329973	[248,237]	[281,191]	3	hSpCas9	negative selection	4708109
64068996	64069018	7	+	27760321	HT1080	viability	TACGGAAACCTGTTCTCCTTGG	ZNF727	ENSG00000214652	-0.26948169832411906	[236,184]	[21,121]	-1	hSpCas9	negative selection	4791568
64069560	64069582	7	+	27760321	HT1080	viability	AAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	2.4337294850494366	[472,368]	[1034,764]	9	hSpCas9	negative selection	4791569
64069589	64069611	7	+	27760321	HT1080	viability	AGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-7.232538298469271	[423,330]	[0,0]	-9	hSpCas9	negative selection	4791570
64077401	64077423	7	+	27760321	HT1080	viability	CAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	0.2599288307871866	[437,341]	[207,161]	1	hSpCas9	negative selection	4791571
64077468	64077490	7	-	27760321	HT1080	viability	TATTGACAGGTTTTGCTACGGG	ZNF727	ENSG00000214652	0.6188927046482393	[237,185]	[112,147]	3	hSpCas9	negative selection	4791572
64068996	64069018	7	+	27760321	HT29	viability after 7 days	TACGGAAACCTGTTCTCCTTGG	ZNF727	ENSG00000214652	-0.29803677450949095	[236,184]	[221,287,153]	-4	hSpCas9	negative selection	4875031
64069560	64069582	7	+	27760321	HT29	viability after 7 days	AAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.0840675630535464	[472,368]	[641,636,454]	1	hSpCas9	negative selection	4875032
64069589	64069611	7	+	27760321	HT29	viability after 7 days	AGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-0.861132037383129	[423,330]	[307,325,175]	-8	hSpCas9	negative selection	4875033
64077401	64077423	7	+	27760321	HT29	viability after 7 days	CAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	0.06636568800581896	[437,341]	[780,276,551]	1	hSpCas9	negative selection	4875034
64077468	64077490	7	-	27760321	HT29	viability after 7 days	TATTGACAGGTTTTGCTACGGG	ZNF727	ENSG00000214652	-0.11834058567776728	[237,185]	[184,415,145]	-2	hSpCas9	negative selection	4875035
64068996	64069018	7	+	27760321	HT29	viability after 25 days	TACGGAAACCTGTTCTCCTTGG	ZNF727	ENSG00000214652	0.5668892446329393	[236,184]	[316,395,360]	6	hSpCas9	negative selection	4958494
64069560	64069582	7	+	27760321	HT29	viability after 25 days	AAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.7140072622659553	[472,368]	[876,684,799]	7	hSpCas9	negative selection	4958495
64069589	64069611	7	+	27760321	HT29	viability after 25 days	AGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-3.2622962107765834	[423,330]	[77,41,8]	-8	hSpCas9	negative selection	4958496
64077401	64077423	7	+	27760321	HT29	viability after 25 days	CAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	-0.48246390770708797	[437,341]	[290,290,382]	-4	hSpCas9	negative selection	4958497
64077468	64077490	7	-	27760321	HT29	viability after 25 days	TATTGACAGGTTTTGCTACGGG	ZNF727	ENSG00000214652	0.3723769610553777	[237,185]	[298,314,328]	4	hSpCas9	negative selection	4958498
64068996	64069018	7	+	27760321	HT29	viability after 22 days	TACGGAAACCTGTTCTCCTTGG	ZNF727	ENSG00000214652	0.46701755604719625	[236,184]	[290,357,363]	5	hSpCas9	negative selection	5041957
64069560	64069582	7	+	27760321	HT29	viability after 22 days	AAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.4488365123190394	[472,368]	[840,490,655]	5	hSpCas9	negative selection	5041958
64069589	64069611	7	+	27760321	HT29	viability after 22 days	AGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-3.5798220202497033	[423,330]	[6,96,5]	-9	hSpCas9	negative selection	5041959
64077401	64077423	7	+	27760321	HT29	viability after 22 days	CAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	-0.2757230844273393	[437,341]	[358,245,513]	-3	hSpCas9	negative selection	5041960
64077468	64077490	7	-	27760321	HT29	viability after 22 days	TATTGACAGGTTTTGCTACGGG	ZNF727	ENSG00000214652	-0.10039473353986916	[237,185]	[207,189,288]	-1	hSpCas9	negative selection	5041961
64068996	64069018	7	+	27760321	HT29	viability after 19 days	TACGGAAACCTGTTCTCCTTGG	ZNF727	ENSG00000214652	0.3211457871171266	[236,184]	[374,370,170]	3	hSpCas9	negative selection	5125420
64069560	64069582	7	+	27760321	HT29	viability after 19 days	AAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.1687696299666634	[472,368]	[590,803,244]	1	hSpCas9	negative selection	5125421
64069589	64069611	7	+	27760321	HT29	viability after 19 days	AGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-1.3054157917057652	[423,330]	[109,361,49]	-7	hSpCas9	negative selection	5125422
64077401	64077423	7	+	27760321	HT29	viability after 19 days	CAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	-0.6867534256015764	[437,341]	[290,87,446]	-5	hSpCas9	negative selection	5125423
64077468	64077490	7	-	27760321	HT29	viability after 19 days	TATTGACAGGTTTTGCTACGGG	ZNF727	ENSG00000214652	0.06491774058621724	[237,185]	[298,279,188]	0	hSpCas9	negative selection	5125424
64068996	64069018	7	+	27760321	HT29	viability after 16 days	TACGGAAACCTGTTCTCCTTGG	ZNF727	ENSG00000214652	0.5368776463231657	[236,184]	[250,257,511]	6	hSpCas9	negative selection	5208883
64069560	64069582	7	+	27760321	HT29	viability after 16 days	AAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.12037590111487645	[472,368]	[690,465,396]	1	hSpCas9	negative selection	5208884
64069589	64069611	7	+	27760321	HT29	viability after 16 days	AGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-3.2730709202874273	[423,330]	[56,55,18]	-9	hSpCas9	negative selection	5208885
64077401	64077423	7	+	27760321	HT29	viability after 16 days	CAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	0.31435782992463907	[437,341]	[393,565,652]	3	hSpCas9	negative selection	5208886
64077468	64077490	7	-	27760321	HT29	viability after 16 days	TATTGACAGGTTTTGCTACGGG	ZNF727	ENSG00000214652	0.35670509473219003	[237,185]	[633,164,146]	4	hSpCas9	negative selection	5208887
64068996	64069018	7	+	27760321	HT29	viability after 13 days	TACGGAAACCTGTTCTCCTTGG	ZNF727	ENSG00000214652	0.6956854711402746	[236,184]	[569,274,346]	8	hSpCas9	negative selection	5292346
64069560	64069582	7	+	27760321	HT29	viability after 13 days	AAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.3146411018525247	[472,368]	[537,688,595]	4	hSpCas9	negative selection	5292347
64069589	64069611	7	+	27760321	HT29	viability after 13 days	AGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-2.1166779978324626	[423,330]	[93,108,99]	-8	hSpCas9	negative selection	5292348
64077401	64077423	7	+	27760321	HT29	viability after 13 days	CAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	-0.0059505859378018305	[437,341]	[275,708,371]	0	hSpCas9	negative selection	5292349
64077468	64077490	7	-	27760321	HT29	viability after 13 days	TATTGACAGGTTTTGCTACGGG	ZNF727	ENSG00000214652	-0.25273932292704837	[237,185]	[254,137,224]	-3	hSpCas9	negative selection	5292350
64068996	64069018	7	+	27760321	HT29	viability after 10 days	TACGGAAACCTGTTCTCCTTGG	ZNF727	ENSG00000214652	0.21734941821588816	[236,184]	[281,240,391]	3	hSpCas9	negative selection	5375809
64069560	64069582	7	+	27760321	HT29	viability after 10 days	AAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.39273995874702694	[472,368]	[497,772,798]	5	hSpCas9	negative selection	5375810
64069589	64069611	7	+	27760321	HT29	viability after 10 days	AGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-1.2135392187894545	[423,330]	[305,42,254]	-8	hSpCas9	negative selection	5375811
64077401	64077423	7	+	27760321	HT29	viability after 10 days	CAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	-0.1734859799491013	[437,341]	[555,390,348]	-2	hSpCas9	negative selection	5375812
64077468	64077490	7	-	27760321	HT29	viability after 10 days	TATTGACAGGTTTTGCTACGGG	ZNF727	ENSG00000214652	-0.459470090716691	[237,185]	[143,243,190]	-5	hSpCas9	negative selection	5375813
64068996	64069018	7	+	27760321	MOLM13	viability	TACGGAAACCTGTTCTCCTTGG	ZNF727	ENSG00000214652	-0.9327689815153806	[341,236]	[49,113]	-5	hSpCas9	negative selection	5459272
64069560	64069582	7	+	27760321	MOLM13	viability	AAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.7112596707407572	[581,472]	[521,452]	5	hSpCas9	negative selection	5459273
64069589	64069611	7	+	27760321	MOLM13	viability	AGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-2.208333116940068	[527,423]	[53,60]	-8	hSpCas9	negative selection	5459274
64077401	64077423	7	+	27760321	MOLM13	viability	CAACGTGTGGGTAATTGCAAGG	ZNF727	ENSG00000214652	-1.4593680005228515	[508,437]	[64,123]	-7	hSpCas9	negative selection	5459275
64077468	64077490	7	-	27760321	MOLM13	viability	TATTGACAGGTTTTGCTACGGG	ZNF727	ENSG00000214652	-0.5743833951538276	[248,237]	[113,73]	-4	hSpCas9	negative selection	5459276
64045592	64045615	7	+	27661255	K562	viability	GAAGAAGGCGGAACATCCGGAGG	ZNF727	ENSG00000214652	0.10504978963725131	[1622,1695]	[1463,1390]	3	dCas9-KRAB	negative selection	5525650
64045529	64045552	7	-	27661255	K562	viability	GGGCTATGGTGGAGTCACCGAGG	ZNF727	ENSG00000214652	0.17263154188009078	[1725,1767]	[1643,1510]	6	dCas9-KRAB	negative selection	5525651
64045847	64045870	7	-	27661255	K562	viability	GAGCTGCCCAAAAAGTCTCTGGG	ZNF727	ENSG00000214652	0.5139852230696262	[92,147]	[131,139]	9	dCas9-KRAB	negative selection	5525652
64068886	64068909	7	+	27260156	BXPC3	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	-0.0038563932729505923	[543]	[582,538,576,565]	0	hSpCas9	negative selection	5582709
64069559	64069582	7	+	27260156	BXPC3	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.3529457591293128	[156]	[236,170,198,231]	7	hSpCas9	negative selection	5582710
64069567	64069590	7	-	27260156	BXPC3	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.6891845551690541	[762]	[1100,1309,1345,1414]	9	hSpCas9	negative selection	5582711
64077480	64077503	7	-	27260156	BXPC3	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.1745128234892005	[587]	[423,586,568,614]	-4	hSpCas9	negative selection	5646956
64077370	64077393	7	-	27260156	BXPC3	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	-0.18254641335108945	[377]	[357,284,346,410]	-4	hSpCas9	negative selection	5646957
64069004	64069027	7	-	27260156	BXPC3	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.1288811359371973	[187]	[231,212,196,213]	3	hSpCas9	negative selection	5646958
64068886	64068909	7	+	27260156	A673	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.05503081625673675	[543]	[727,728,571,689]	1	hSpCas9	negative selection	5703960
64069559	64069582	7	+	27260156	A673	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.46740964053174716	[156]	[345,240,174,292]	9	hSpCas9	negative selection	5703961
64069567	64069590	7	-	27260156	A673	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.7052280947852367	[762]	[1484,1455,1352,1689]	9	hSpCas9	negative selection	5703962
64077480	64077503	7	-	27260156	A673	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.3294153373998174	[587]	[509,594,477,662]	-7	hSpCas9	negative selection	5768207
64077370	64077393	7	-	27260156	A673	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	-0.15388600637244293	[377]	[416,351,500,359]	-4	hSpCas9	negative selection	5768208
64069004	64069027	7	-	27260156	A673	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.22811092715882642	[187]	[362,170,240,297]	5	hSpCas9	negative selection	5768209
64068886	64068909	7	+	27260156	A375	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.4593399643534546	[543]	[1059,734,1006,692]	6	hSpCas9	negative selection	5825211
64069559	64069582	7	+	27260156	A375	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	1.054767423011329	[156]	[534,506,321,198]	9	hSpCas9	negative selection	5825212
64069567	64069590	7	-	27260156	A375	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.6777123183469214	[762]	[1613,1550,1213,1345]	8	hSpCas9	negative selection	5825213
64077480	64077503	7	-	27260156	A375	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	0.10220054024414499	[587]	[473,1224,789,545]	1	hSpCas9	negative selection	5889458
64077370	64077393	7	-	27260156	A375	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.47459286610138185	[377]	[476,778,589,625]	7	hSpCas9	negative selection	5889459
64069004	64069027	7	-	27260156	A375	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.28728719617214415	[187]	[262,256,241,302]	4	hSpCas9	negative selection	5889460
64068886	64068909	7	+	27260156	COLO741	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.0978429522931478	[543]	[756,869,613]	2	hSpCas9	negative selection	5946462
64069559	64069582	7	+	27260156	COLO741	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.36971782064341485	[156]	[268,293,217]	7	hSpCas9	negative selection	5946463
64069567	64069590	7	-	27260156	COLO741	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.6565594434918236	[762]	[1567,1457,1579]	9	hSpCas9	negative selection	5946464
64077480	64077503	7	-	27260156	COLO741	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.22259968371683903	[587]	[779,636,532]	-5	hSpCas9	negative selection	6010709
64077370	64077393	7	-	27260156	COLO741	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.030418584244259306	[377]	[547,438,495]	0	hSpCas9	negative selection	6010710
64069004	64069027	7	-	27260156	COLO741	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.28168262660602217	[187]	[217,369,281]	6	hSpCas9	negative selection	6010711
64068886	64068909	7	+	27260156	CAL120	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.4330385969082895	[543]	[981,1154,619]	6	hSpCas9	negative selection	6067713
64069559	64069582	7	+	27260156	CAL120	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	-0.23623583147479343	[156]	[201,137,162]	-3	hSpCas9	negative selection	6067714
64069567	64069590	7	-	27260156	CAL120	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.5742049402559197	[762]	[1622,1023,1620]	8	hSpCas9	negative selection	6067715
64077480	64077503	7	-	27260156	CAL120	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.01598883640502774	[587]	[1390,490,394]	0	hSpCas9	negative selection	6131960
64077370	64077393	7	-	27260156	CAL120	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.050034816505381274	[377]	[699,317,474]	0	hSpCas9	negative selection	6131961
64069004	64069027	7	-	27260156	CAL120	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	-0.20326803994983322	[187]	[148,228,222]	-3	hSpCas9	negative selection	6131962
64068886	64068909	7	+	27260156	CADOES1	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.19581536012499193	[543]	[527,744,478,565]	3	hSpCas9	negative selection	6188964
64069559	64069582	7	+	27260156	CADOES1	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.7346318588606114	[156]	[224,174,322,248]	9	hSpCas9	negative selection	6188965
64069567	64069590	7	-	27260156	CADOES1	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.6501366415356309	[762]	[1053,1185,995,1222]	9	hSpCas9	negative selection	6188966
64077480	64077503	7	-	27260156	CADOES1	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.07230269133060102	[587]	[456,488,528,608]	-1	hSpCas9	negative selection	6253211
64077370	64077393	7	-	27260156	CADOES1	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.6427906891373101	[377]	[657,469,548,516]	9	hSpCas9	negative selection	6253212
64069004	64069027	7	-	27260156	CADOES1	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.16536184502685392	[187]	[144,233,197,207]	3	hSpCas9	negative selection	6253213
64068886	64068909	7	+	27260156	EWS502	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.23125910934483132	[543]	[595,693,695,729]	4	hSpCas9	negative selection	6310215
64069559	64069582	7	+	27260156	EWS502	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.9903534133288527	[156]	[346,280,339,353]	9	hSpCas9	negative selection	6310216
64069567	64069590	7	-	27260156	EWS502	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.6796046802497473	[762]	[1407,1211,1207,1335]	9	hSpCas9	negative selection	6310217
64077480	64077503	7	-	27260156	EWS502	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	0.04662724457000128	[587]	[522,605,704,761]	0	hSpCas9	negative selection	6374462
64077370	64077393	7	-	27260156	EWS502	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.20743751108433434	[377]	[439,461,475,472]	3	hSpCas9	negative selection	6374463
64069004	64069027	7	-	27260156	EWS502	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.07005126137592854	[187]	[96,201,327,224]	1	hSpCas9	negative selection	6374464
64068886	64068909	7	+	27260156	EW8	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	-0.11402462100460693	[543]	[417,425,392,394]	-2	hSpCas9	negative selection	6431466
64069559	64069582	7	+	27260156	EW8	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.5269711980087353	[156]	[216,184,162,174]	8	hSpCas9	negative selection	6431467
64069567	64069590	7	-	27260156	EW8	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.9178753695052062	[762]	[1343,885,1169,1286]	9	hSpCas9	negative selection	6431468
64077480	64077503	7	-	27260156	EW8	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.16508973643878957	[587]	[479,515,326,398]	-3	hSpCas9	negative selection	6495713
64077370	64077393	7	-	27260156	EW8	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.2295689721197509	[377]	[536,368,267,296]	4	hSpCas9	negative selection	6495714
64069004	64069027	7	-	27260156	EW8	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.5032582488283408	[187]	[238,222,184,223]	8	hSpCas9	negative selection	6495715
64068886	64068909	7	+	27260156	CORL105	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.13260384880709317	[543]	[877,656,835,450]	2	hSpCas9	negative selection	6552717
64069559	64069582	7	+	27260156	CORL105	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.5509865652147108	[156]	[314,344,277,140]	8	hSpCas9	negative selection	6552718
64069567	64069590	7	-	27260156	CORL105	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.6430091134594296	[762]	[1312,1473,1353,1426]	9	hSpCas9	negative selection	6552719
64077480	64077503	7	-	27260156	CORL105	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.10197349298477268	[587]	[657,522,748,654]	-2	hSpCas9	negative selection	6616964
64077370	64077393	7	-	27260156	CORL105	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.09506630392936793	[377]	[507,433,519,437]	1	hSpCas9	negative selection	6616965
64069004	64069027	7	-	27260156	CORL105	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	-0.0031285851178415314	[187]	[230,210,244,195]	0	hSpCas9	negative selection	6616966
64068886	64068909	7	+	27260156	HS294T	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.4471852285365272	[543]	[430,206,213,281]	6	hSpCas9	negative selection	6673968
64069559	64069582	7	+	27260156	HS294T	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.6589660304267554	[156]	[70,81,156,71]	8	hSpCas9	negative selection	6673969
64069567	64069590	7	-	27260156	HS294T	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	1.0635289776124845	[762]	[530,525,565,899]	9	hSpCas9	negative selection	6673970
64077480	64077503	7	-	27260156	HS294T	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	0.05377967017809482	[587]	[240,172,143,416]	0	hSpCas9	negative selection	6738215
64077370	64077393	7	-	27260156	HS294T	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	-0.461902280204104	[377]	[101,114,111,92]	-6	hSpCas9	negative selection	6738216
64069004	64069027	7	-	27260156	HS294T	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	-0.375389807248073	[187]	[73,56,35,54]	-5	hSpCas9	negative selection	6738217
64068886	64068909	7	+	27260156	HCC44	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.3056459222607465	[543]	[582,769,984,719]	5	hSpCas9	negative selection	6795219
64069559	64069582	7	+	27260156	HCC44	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.14064042214482075	[156]	[234,187,250,123]	2	hSpCas9	negative selection	6795220
64069567	64069590	7	-	27260156	HCC44	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.677848109918453	[762]	[1622,982,1659,1371]	9	hSpCas9	negative selection	6795221
64077480	64077503	7	-	27260156	HCC44	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.2029870523908541	[587]	[424,815,473,526]	-3	hSpCas9	negative selection	6859466
64077370	64077393	7	-	27260156	HCC44	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	-0.08314913069731322	[377]	[299,251,796,343]	-1	hSpCas9	negative selection	6859467
64069004	64069027	7	-	27260156	HCC44	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.29376302911755325	[187]	[209,304,186,312]	5	hSpCas9	negative selection	6859468
64068886	64068909	7	+	27260156	G402	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.3076752005161556	[543]	[841,668,1130,643]	4	hSpCas9	negative selection	6916470
64069559	64069582	7	+	27260156	G402	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.4689127969911635	[156]	[259,229,369,199]	6	hSpCas9	negative selection	6916471
64069567	64069590	7	-	27260156	G402	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	1.1908111625483295	[762]	[2387,2503,1980,1700]	9	hSpCas9	negative selection	6916472
64077480	64077503	7	-	27260156	G402	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	0.13404321664779123	[587]	[578,908,587,1034]	1	hSpCas9	negative selection	6980717
64077370	64077393	7	-	27260156	G402	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.24538414257050223	[377]	[948,685,300,325]	3	hSpCas9	negative selection	6980718
64069004	64069027	7	-	27260156	G402	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.4297810392713378	[187]	[606,249,162,256]	5	hSpCas9	negative selection	6980719
64068886	64068909	7	+	27260156	L33	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	-0.04271053884979806	[543]	[420,283,372,408]	-1	hSpCas9	negative selection	7037721
64069559	64069582	7	+	27260156	L33	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.5024583143075085	[156]	[217,74,103,321]	8	hSpCas9	negative selection	7037722
64069567	64069590	7	-	27260156	L33	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.6020887894720361	[762]	[1181,511,701,1083]	9	hSpCas9	negative selection	7037723
64077480	64077503	7	-	27260156	L33	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.20795476484913678	[587]	[396,239,345,505]	-5	hSpCas9	negative selection	7101968
64077370	64077393	7	-	27260156	L33	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	-0.07994836874645711	[377]	[414,121,221,362]	-2	hSpCas9	negative selection	7101969
64069004	64069027	7	-	27260156	L33	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.062445446167888274	[187]	[233,97,103,145]	1	hSpCas9	negative selection	7101970
64068886	64068909	7	+	27260156	K562	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.3131367832280797	[543]	[387,749,534,701]	4	hSpCas9	negative selection	7158972
64069559	64069582	7	+	27260156	K562	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	1.5888467821603787	[156]	[458,263,878,104]	9	hSpCas9	negative selection	7158973
64069567	64069590	7	-	27260156	K562	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.6961175365224725	[762]	[1447,781,1072,1092]	8	hSpCas9	negative selection	7158974
64077480	64077503	7	-	27260156	K562	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.22827476969072993	[587]	[499,441,432,412]	-3	hSpCas9	negative selection	7223219
64077370	64077393	7	-	27260156	K562	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.24369804228131595	[377]	[427,239,437,466]	3	hSpCas9	negative selection	7223220
64069004	64069027	7	-	27260156	K562	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	-0.24454784557243214	[187]	[168,139,124,131]	-3	hSpCas9	negative selection	7223221
64068886	64068909	7	+	27260156	HT29	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	-0.1036003092664408	[543]	[548,723,531,651]	-2	hSpCas9	negative selection	7280223
64069559	64069582	7	+	27260156	HT29	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.3911894291278215	[156]	[272,258,202,264]	7	hSpCas9	negative selection	7280224
64069567	64069590	7	-	27260156	HT29	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.8434005968269638	[762]	[1672,1736,1867,1405]	9	hSpCas9	negative selection	7280225
64077480	64077503	7	-	27260156	HT29	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.14490502816385098	[587]	[584,738,735,537]	-3	hSpCas9	negative selection	7344470
64077370	64077393	7	-	27260156	HT29	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.20499878077741893	[377]	[548,834,457,325]	4	hSpCas9	negative selection	7344471
64069004	64069027	7	-	27260156	HT29	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.5695744794073416	[187]	[528,247,325,266]	9	hSpCas9	negative selection	7344472
64068886	64068909	7	+	27260156	MHHES1	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	-0.08355406940769805	[543]	[532,693,807,330]	-1	hSpCas9	negative selection	7401474
64069559	64069582	7	+	27260156	MHHES1	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.7921373707774311	[156]	[373,217,404,236]	9	hSpCas9	negative selection	7401475
64069567	64069590	7	-	27260156	MHHES1	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.9177050227124142	[762]	[2090,1747,1604,1184]	9	hSpCas9	negative selection	7401476
64077480	64077503	7	-	27260156	MHHES1	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.16124199716801718	[587]	[808,502,687,414]	-3	hSpCas9	negative selection	7465721
64077370	64077393	7	-	27260156	MHHES1	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.5601998460024356	[377]	[674,788,551,525]	8	hSpCas9	negative selection	7465722
64069004	64069027	7	-	27260156	MHHES1	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.5865700230737263	[187]	[417,298,339,236]	8	hSpCas9	negative selection	7465723
64068886	64068909	7	+	27260156	MEWO	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.09946097853523658	[543]	[717,371,579]	2	hSpCas9	negative selection	7522725
64069559	64069582	7	+	27260156	MEWO	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.8295073218855274	[156]	[240,287,249]	9	hSpCas9	negative selection	7522726
64069567	64069590	7	-	27260156	MEWO	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.4528766029017848	[762]	[873,1187,847]	8	hSpCas9	negative selection	7522727
64077480	64077503	7	-	27260156	MEWO	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.13415571714614433	[587]	[543,491,475]	-3	hSpCas9	negative selection	7586972
64077370	64077393	7	-	27260156	MEWO	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.25415457374165096	[377]	[514,476,290]	5	hSpCas9	negative selection	7586973
64069004	64069027	7	-	27260156	MEWO	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.877961272181645	[187]	[275,423,259]	9	hSpCas9	negative selection	7586974
64068886	64068909	7	+	27260156	LNCAPCLONEFGC	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	-0.12407667898475908	[543]	[438,451,595,342]	-2	hSpCas9	negative selection	7643976
64069559	64069582	7	+	27260156	LNCAPCLONEFGC	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.561365980009884	[156]	[163,217,211,245]	8	hSpCas9	negative selection	7643977
64069567	64069590	7	-	27260156	LNCAPCLONEFGC	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.8487737520734917	[762]	[1100,1360,1538,1015]	9	hSpCas9	negative selection	7643978
64077480	64077503	7	-	27260156	LNCAPCLONEFGC	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.03760669604223338	[587]	[605,525,422,503]	0	hSpCas9	negative selection	7708223
64077370	64077393	7	-	27260156	LNCAPCLONEFGC	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.3199914841459345	[377]	[530,410,416,347]	5	hSpCas9	negative selection	7708224
64069004	64069027	7	-	27260156	LNCAPCLONEFGC	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.1163182271979668	[187]	[120,166,206,248]	1	hSpCas9	negative selection	7708225
64068886	64068909	7	+	27260156	PANC0327	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.05296496027142836	[543]	[558,338,633,498]	0	hSpCas9	negative selection	7765227
64069559	64069582	7	+	27260156	PANC0327	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.7982872142158524	[156]	[86,200,435,238]	9	hSpCas9	negative selection	7765228
64069567	64069590	7	-	27260156	PANC0327	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.6656311367203687	[762]	[1286,890,926,1235]	8	hSpCas9	negative selection	7765229
64077480	64077503	7	-	27260156	PANC0327	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.2037658375775006	[587]	[722,306,440,383]	-3	hSpCas9	negative selection	7829474
64077370	64077393	7	-	27260156	PANC0327	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.2342943255074667	[377]	[376,317,719,173]	3	hSpCas9	negative selection	7829475
64069004	64069027	7	-	27260156	PANC0327	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.32851490113910575	[187]	[204,86,155,405]	5	hSpCas9	negative selection	7829476
64068886	64068909	7	+	27260156	NCIH2009	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.3954980075333553	[543]	[907,970,1100]	5	hSpCas9	negative selection	7886478
64069559	64069582	7	+	27260156	NCIH2009	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.5321233329829775	[156]	[464,331,182]	7	hSpCas9	negative selection	7886479
64069567	64069590	7	-	27260156	NCIH2009	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.6923780339381653	[762]	[2041,1564,1623]	8	hSpCas9	negative selection	7886480
64077480	64077503	7	-	27260156	NCIH2009	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.11984040523053596	[587]	[786,643,843]	-2	hSpCas9	negative selection	7950725
64077370	64077393	7	-	27260156	NCIH2009	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.33921842225615145	[377]	[849,566,623]	4	hSpCas9	negative selection	7950726
64069004	64069027	7	-	27260156	NCIH2009	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.12570625719979756	[187]	[238,222,388]	1	hSpCas9	negative selection	7950727
64068886	64068909	7	+	27260156	NCIH1373	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.6030686235599197	[543]	[1756,656,510,247]	6	hSpCas9	negative selection	8007729
64069559	64069582	7	+	27260156	NCIH1373	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	-0.18542431654486036	[156]	[278,123,163,17]	-2	hSpCas9	negative selection	8007730
64069567	64069590	7	-	27260156	NCIH1373	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	1.0470272929944766	[762]	[2809,1098,1685,445]	9	hSpCas9	negative selection	8007731
64077480	64077503	7	-	27260156	NCIH1373	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	0.2600066074062532	[587]	[644,1064,724,172]	2	hSpCas9	negative selection	8071976
64077370	64077393	7	-	27260156	NCIH1373	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.5391796909228739	[377]	[764,475,744,131]	5	hSpCas9	negative selection	8071977
64069004	64069027	7	-	27260156	NCIH1373	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.41839186985054344	[187]	[307,164,300,97]	4	hSpCas9	negative selection	8071978
64068886	64068909	7	+	27260156	PATU8902	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.559617517931439	[543]	[1124,1293,818,1321]	6	hSpCas9	negative selection	8128980
64069559	64069582	7	+	27260156	PATU8902	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	1.1358623984897158	[156]	[395,589,493,429]	9	hSpCas9	negative selection	8128981
64069567	64069590	7	-	27260156	PATU8902	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.9781062569115697	[762]	[2059,2093,1498,2961]	9	hSpCas9	negative selection	8128982
64077480	64077503	7	-	27260156	PATU8902	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	0.5865694824645142	[587]	[835,1367,623,2381]	6	hSpCas9	negative selection	8193227
64077370	64077393	7	-	27260156	PATU8902	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.5197132072488334	[377]	[462,840,484,1371]	5	hSpCas9	negative selection	8193228
64069004	64069027	7	-	27260156	PATU8902	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.42024002139608296	[187]	[372,350,205,526]	4	hSpCas9	negative selection	8193229
64068886	64068909	7	+	27260156	PANC1	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.1327402017794628	[543]	[482,657,639,322]	2	hSpCas9	negative selection	8250231
64069559	64069582	7	+	27260156	PANC1	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.3748197250637251	[156]	[113,284,144,175]	6	hSpCas9	negative selection	8250232
64069567	64069590	7	-	27260156	PANC1	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.7659864049812055	[762]	[1099,1176,1240,960]	9	hSpCas9	negative selection	8250233
64077480	64077503	7	-	27260156	PANC1	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	0.08520261270932455	[587]	[440,599,667,454]	1	hSpCas9	negative selection	8314478
64077370	64077393	7	-	27260156	PANC1	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.15675079078753634	[377]	[399,640,258,220]	2	hSpCas9	negative selection	8314479
64069004	64069027	7	-	27260156	PANC1	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.2471414739232798	[187]	[157,171,182,238]	4	hSpCas9	negative selection	8314480
64068886	64068909	7	+	27260156	PANC0813	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.1706697780639693	[543]	[716,771,695,691]	2	hSpCas9	negative selection	8371482
64069559	64069582	7	+	27260156	PANC0813	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.6549247112539536	[156]	[246,242,437,232]	9	hSpCas9	negative selection	8371483
64069567	64069590	7	-	27260156	PANC0813	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.8104692723967277	[762]	[1707,1483,1564,1541]	9	hSpCas9	negative selection	8371484
64077480	64077503	7	-	27260156	PANC0813	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.03465544404082527	[587]	[689,849,679,487]	0	hSpCas9	negative selection	8435729
64077370	64077393	7	-	27260156	PANC0813	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.16966494698193305	[377]	[524,382,544,543]	2	hSpCas9	negative selection	8435730
64069004	64069027	7	-	27260156	PANC0813	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.33543913661885616	[187]	[286,410,152,263]	5	hSpCas9	negative selection	8435731
64068886	64068909	7	+	27260156	RDES	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.3494119003198569	[543]	[676,821,871,821]	5	hSpCas9	negative selection	8492733
64069559	64069582	7	+	27260156	RDES	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.6458456204688775	[156]	[242,286,276,328]	9	hSpCas9	negative selection	8492734
64069567	64069590	7	-	27260156	RDES	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.8745897964933336	[762]	[1299,1538,1651,2035]	9	hSpCas9	negative selection	8492735
64077480	64077503	7	-	27260156	RDES	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.0029086843501432424	[587]	[557,653,600,928]	0	hSpCas9	negative selection	8556980
64077370	64077393	7	-	27260156	RDES	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.4616717678635701	[377]	[449,752,589,599]	7	hSpCas9	negative selection	8556981
64069004	64069027	7	-	27260156	RDES	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.3570257172956587	[187]	[283,274,272,261]	6	hSpCas9	negative selection	8556982
64068886	64068909	7	+	27260156	PC3	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.1626003700367946	[543]	[377,756,1028,452]	3	hSpCas9	negative selection	8613984
64069559	64069582	7	+	27260156	PC3	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.5018789441923774	[156]	[147,251,312,215]	8	hSpCas9	negative selection	8613985
64069567	64069590	7	-	27260156	PC3	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.5746476583526632	[762]	[697,1166,2038,1055]	9	hSpCas9	negative selection	8613986
64077480	64077503	7	-	27260156	PC3	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.4601679479076185	[587]	[242,376,762,500]	-8	hSpCas9	negative selection	8678231
64077370	64077393	7	-	27260156	PC3	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.04912515052820865	[377]	[271,427,543,381]	1	hSpCas9	negative selection	8678232
64069004	64069027	7	-	27260156	PC3	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	-0.01866477706873737	[187]	[148,191,197,198]	0	hSpCas9	negative selection	8678233
64068886	64068909	7	+	27260156	PATU8988T	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.21478862130321755	[543]	[687,838,283,658]	3	hSpCas9	negative selection	8735235
64069559	64069582	7	+	27260156	PATU8988T	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	1.3111310462377848	[156]	[198,646,269,419]	9	hSpCas9	negative selection	8735236
64069567	64069590	7	-	27260156	PATU8988T	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.24708858131098854	[762]	[909,973,701,929]	4	hSpCas9	negative selection	8735237
64077480	64077503	7	-	27260156	PATU8988T	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.19912619243111068	[587]	[331,454,643,546]	-3	hSpCas9	negative selection	8799482
64077370	64077393	7	-	27260156	PATU8988T	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	-0.3795339567202283	[377]	[199,353,242,337]	-6	hSpCas9	negative selection	8799483
64069004	64069027	7	-	27260156	PATU8988T	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.11625152434090746	[187]	[55,166,210,363]	2	hSpCas9	negative selection	8799484
64068886	64068909	7	+	27260156	T47D	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.007813116384491031	[543]	[566,568,696,722]	0	hSpCas9	negative selection	8856486
64069559	64069582	7	+	27260156	T47D	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.45668553949975843	[156]	[278,242,253,227]	8	hSpCas9	negative selection	8856487
64069567	64069590	7	-	27260156	T47D	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.520041560735073	[762]	[1179,1259,1389,1266]	9	hSpCas9	negative selection	8856488
64077480	64077503	7	-	27260156	T47D	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	0.0654015068027185	[587]	[734,646,694,798]	1	hSpCas9	negative selection	8920733
64077370	64077393	7	-	27260156	T47D	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.014162200168882866	[377]	[462,376,555,384]	0	hSpCas9	negative selection	8920734
64069004	64069027	7	-	27260156	T47D	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.12967064121558924	[187]	[233,250,221,250]	2	hSpCas9	negative selection	8920735
64068886	64068909	7	+	27260156	SU8686	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.24727390634469845	[543]	[546,572,728,745]	4	hSpCas9	negative selection	8977737
64069559	64069582	7	+	27260156	SU8686	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.7598040692191597	[156]	[269,154,373,270]	9	hSpCas9	negative selection	8977738
64069567	64069590	7	-	27260156	SU8686	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.7727029336172804	[762]	[1217,1159,1185,1681]	9	hSpCas9	negative selection	8977739
64077480	64077503	7	-	27260156	SU8686	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	0.06516625346667904	[587]	[580,423,570,938]	1	hSpCas9	negative selection	9041984
64077370	64077393	7	-	27260156	SU8686	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.20682643090633693	[377]	[438,320,395,612]	3	hSpCas9	negative selection	9041985
64069004	64069027	7	-	27260156	SU8686	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.3869977799652946	[187]	[189,149,419,234]	6	hSpCas9	negative selection	9041986
64068886	64068909	7	+	27260156	SKES1	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	-0.017230458596035142	[543]	[827,522,498,350]	0	hSpCas9	negative selection	9098988
64069559	64069582	7	+	27260156	SKES1	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.5968641714099743	[156]	[221,389,124,226]	9	hSpCas9	negative selection	9098989
64069567	64069590	7	-	27260156	SKES1	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.6326921141032165	[762]	[1387,1256,1118,1003]	9	hSpCas9	negative selection	9098990
64077480	64077503	7	-	27260156	SKES1	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.16896865842162906	[587]	[482,645,482,483]	-4	hSpCas9	negative selection	9163235
64077370	64077393	7	-	27260156	SKES1	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.05743848811204644	[377]	[304,362,379,489]	1	hSpCas9	negative selection	9163236
64069004	64069027	7	-	27260156	SKES1	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.4116539260977593	[187]	[293,363,181,183]	8	hSpCas9	negative selection	9163237
64068886	64068909	7	+	27260156	TOV112D	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.07152167483883462	[543]	[615,535,636,496]	1	hSpCas9	negative selection	9220239
64069559	64069582	7	+	27260156	TOV112D	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.7557333929475372	[156]	[236,291,245,289]	9	hSpCas9	negative selection	9220240
64069567	64069590	7	-	27260156	TOV112D	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.8615336792092032	[762]	[1335,1765,1324,1217]	9	hSpCas9	negative selection	9220241
64077480	64077503	7	-	27260156	TOV112D	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.12030175247719335	[587]	[620,540,513,497]	-2	hSpCas9	negative selection	9284486
64077370	64077393	7	-	27260156	TOV112D	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	-0.19153201501566403	[377]	[141,472,528,203]	-4	hSpCas9	negative selection	9284487
64069004	64069027	7	-	27260156	TOV112D	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.21568892947410068	[187]	[223,279,282,105]	4	hSpCas9	negative selection	9284488
64068886	64068909	7	+	27260156	TC71	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.05953547282845609	[543]	[619,681,525,604]	1	hSpCas9	negative selection	9341490
64069559	64069582	7	+	27260156	TC71	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.42691692815726134	[156]	[187,273,198,246]	8	hSpCas9	negative selection	9341491
64069567	64069590	7	-	27260156	TC71	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.6521306839602594	[762]	[1241,1403,1137,1367]	9	hSpCas9	negative selection	9341492
64077480	64077503	7	-	27260156	TC71	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	-0.17186188245530673	[587]	[606,599,490,539]	-4	hSpCas9	negative selection	9405737
64077370	64077393	7	-	27260156	TC71	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.023165080335364574	[377]	[291,451,431,476]	0	hSpCas9	negative selection	9405738
64069004	64069027	7	-	27260156	TC71	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.34089968424616013	[187]	[174,285,285,275]	7	hSpCas9	negative selection	9405739
64068886	64068909	7	+	27260156	TC32	viability	TTCAGCGAGTGCTAACATTCAGG	ZNF727	ENSG00000214652	0.34411784496682063	[543]	[530,575,946,592]	6	hSpCas9	negative selection	9462741
64069559	64069582	7	+	27260156	TC32	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.9132630222961337	[156]	[131,257,390,364]	9	hSpCas9	negative selection	9462742
64069567	64069590	7	-	27260156	TC32	viability	TTCTGTCTCCTCGCATTCCAAGG	ZNF727	ENSG00000214652	0.7967793535113672	[762]	[1139,779,1932,1375]	9	hSpCas9	negative selection	9462743
64077480	64077503	7	-	27260156	TC32	viability	GCCACATTTATTATATTGACAGG	ZNF727	ENSG00000214652	0.042628137590003556	[587]	[489,465,697,664]	0	hSpCas9	negative selection	9526988
64077370	64077393	7	-	27260156	TC32	viability	TCTTTAAACGTAAAGTATTAAGG	ZNF727	ENSG00000214652	0.24276791092179822	[377]	[365,278,526,572]	4	hSpCas9	negative selection	9526989
64069004	64069027	7	-	27260156	TC32	viability	TATTCTCACCCAAGGAGAACAGG	ZNF727	ENSG00000214652	0.0977614423989479	[187]	[133,121,324,222]	1	hSpCas9	negative selection	9526990
64069559	64069582	7	+	28162770	P31FUJ	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.6482923903168023	[157]	[290]	7	hSpCas9	negative selection	10272498
64078176	64078199	7	-	28162770	P31FUJ	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	0.7480551656796406	[568]	[1122]	8	hSpCas9	negative selection	10272499
64068887	64068910	7	+	28162770	P31FUJ	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.23325929788893196	[374]	[517]	2	hSpCas9	negative selection	10272500
64077388	64077411	7	+	28162770	P31FUJ	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	0.724969560196324	[155]	[302]	8	hSpCas9	negative selection	10272501
64078511	64078534	7	-	28162770	P31FUJ	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	0.25262462275586295	[114]	[160]	2	hSpCas9	negative selection	10272502
64077400	64077423	7	-	28162770	P31FUJ	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	-0.24779137863383183	[386]	[382]	-2	hSpCas9	negative selection	10272503
64077768	64077791	7	-	28162770	P31FUJ	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	0.6329259292291123	[601]	[1096]	7	hSpCas9	negative selection	10272504
64069588	64069611	7	+	28162770	P31FUJ	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-0.5287350907687964	[274]	[223]	-4	hSpCas9	negative selection	10272505
64078428	64078451	7	-	28162770	P31FUJ	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.292742086236383	[916]	[1319]	3	hSpCas9	negative selection	10272506
64078098	64078121	7	-	28162770	P31FUJ	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-0.7649128228697999	[602]	[416]	-5	hSpCas9	negative selection	10272507
64069559	64069582	7	+	28162770	TF1	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	NaN	[NaN]	[292]	1	hSpCas9	negative selection	10441864
64078176	64078199	7	-	28162770	TF1	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	NaN	[NaN]	[588]	1	hSpCas9	negative selection	10441865
64068887	64068910	7	+	28162770	TF1	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	NaN	[NaN]	[576]	1	hSpCas9	negative selection	10441866
64077388	64077411	7	+	28162770	TF1	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	NaN	[NaN]	[398]	1	hSpCas9	negative selection	10441867
64078511	64078534	7	-	28162770	TF1	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	NaN	[NaN]	[86]	1	hSpCas9	negative selection	10441868
64077400	64077423	7	-	28162770	TF1	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	NaN	[NaN]	[182]	1	hSpCas9	negative selection	10441869
64077768	64077791	7	-	28162770	TF1	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	NaN	[NaN]	[722]	1	hSpCas9	negative selection	10441870
64069588	64069611	7	+	28162770	TF1	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	NaN	[NaN]	[125]	1	hSpCas9	negative selection	10441871
64078428	64078451	7	-	28162770	TF1	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	NaN	[NaN]	[1117]	1	hSpCas9	negative selection	10441872
64078098	64078121	7	-	28162770	TF1	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	NaN	[NaN]	[174]	1	hSpCas9	negative selection	10441873
64069559	64069582	7	+	28162770	SKM1	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.7709535934526813	[59]	[180]	7	hSpCas9	negative selection	10611230
64078176	64078199	7	-	28162770	SKM1	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	0.9459328743019664	[105]	[360]	8	hSpCas9	negative selection	10611231
64068887	64068910	7	+	28162770	SKM1	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.802786783192339	[130]	[403]	7	hSpCas9	negative selection	10611232
64077388	64077411	7	+	28162770	SKM1	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	0.9450211300003806	[56]	[193]	8	hSpCas9	negative selection	10611233
64078511	64078534	7	-	28162770	SKM1	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	1.1779983019779945	[29]	[119]	9	hSpCas9	negative selection	10611234
64077400	64077423	7	-	28162770	SKM1	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	0.07346771850668754	[92]	[172]	0	hSpCas9	negative selection	10611235
64077768	64077791	7	-	28162770	SKM1	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	1.034373626332266	[123]	[448]	8	hSpCas9	negative selection	10611236
64069588	64069611	7	+	28162770	SKM1	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	0.5604679388004076	[55]	[145]	5	hSpCas9	negative selection	10611237
64078428	64078451	7	-	28162770	SKM1	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.5099567620026215	[171]	[432]	5	hSpCas9	negative selection	10611238
64078098	64078121	7	-	28162770	SKM1	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-0.01960165790716628	[124]	[217]	0	hSpCas9	negative selection	10611239
64069559	64069582	7	+	28162770	SKM1	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.7709535934526813	[59]	[180]	7	hSpCas9	negative selection	10780596
64078176	64078199	7	-	28162770	SKM1	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	0.9459328743019664	[105]	[360]	8	hSpCas9	negative selection	10780597
64068887	64068910	7	+	28162770	SKM1	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.802786783192339	[130]	[403]	7	hSpCas9	negative selection	10780598
64077388	64077411	7	+	28162770	SKM1	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	0.9450211300003806	[56]	[193]	8	hSpCas9	negative selection	10780599
64078511	64078534	7	-	28162770	SKM1	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	1.1779983019779945	[29]	[119]	9	hSpCas9	negative selection	10780600
64077400	64077423	7	-	28162770	SKM1	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	0.07346771850668754	[92]	[172]	0	hSpCas9	negative selection	10780601
64077768	64077791	7	-	28162770	SKM1	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	1.034373626332266	[123]	[448]	8	hSpCas9	negative selection	10780602
64069588	64069611	7	+	28162770	SKM1	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	0.5604679388004076	[55]	[145]	5	hSpCas9	negative selection	10780603
64078428	64078451	7	-	28162770	SKM1	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.5099567620026215	[171]	[432]	5	hSpCas9	negative selection	10780604
64078098	64078121	7	-	28162770	SKM1	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-0.01960165790716628	[124]	[217]	0	hSpCas9	negative selection	10780605
64069559	64069582	7	+	28162770	PL21	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	-0.2704902107528411	[193]	[69]	-2	hSpCas9	negative selection	10949962
64078176	64078199	7	-	28162770	PL21	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	0.8892667081109534	[324]	[261]	7	hSpCas9	negative selection	10949963
64068887	64068910	7	+	28162770	PL21	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.5900861328053335	[492]	[322]	5	hSpCas9	negative selection	10949964
64077388	64077411	7	+	28162770	PL21	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	0.2781421264905932	[287]	[151]	2	hSpCas9	negative selection	10949965
64078511	64078534	7	-	28162770	PL21	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	1.2631494120151205	[111]	[116]	9	hSpCas9	negative selection	10949966
64077400	64077423	7	-	28162770	PL21	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	0.6151771137681641	[332]	[221]	5	hSpCas9	negative selection	10949967
64077768	64077791	7	-	28162770	PL21	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	0.7508322131257303	[425]	[311]	6	hSpCas9	negative selection	10949968
64069588	64069611	7	+	28162770	PL21	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	0.1862004235314464	[207]	[102]	1	hSpCas9	negative selection	10949969
64078428	64078451	7	-	28162770	PL21	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	1.0155975169748255	[557]	[490]	8	hSpCas9	negative selection	10949970
64078098	64078121	7	-	28162770	PL21	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	0.5160017086773283	[428]	[266]	4	hSpCas9	negative selection	10949971
64069559	64069582	7	+	28162770	P31FUJ	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.6482923903168023	[157]	[290]	7	hSpCas9	negative selection	11119328
64078176	64078199	7	-	28162770	P31FUJ	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	0.7480551656796406	[568]	[1122]	8	hSpCas9	negative selection	11119329
64068887	64068910	7	+	28162770	P31FUJ	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.23325929788893196	[374]	[517]	2	hSpCas9	negative selection	11119330
64077388	64077411	7	+	28162770	P31FUJ	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	0.724969560196324	[155]	[302]	8	hSpCas9	negative selection	11119331
64078511	64078534	7	-	28162770	P31FUJ	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	0.25262462275586295	[114]	[160]	2	hSpCas9	negative selection	11119332
64077400	64077423	7	-	28162770	P31FUJ	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	-0.24779137863383183	[386]	[382]	-2	hSpCas9	negative selection	11119333
64077768	64077791	7	-	28162770	P31FUJ	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	0.6329259292291123	[601]	[1096]	7	hSpCas9	negative selection	11119334
64069588	64069611	7	+	28162770	P31FUJ	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-0.5287350907687964	[274]	[223]	-4	hSpCas9	negative selection	11119335
64078428	64078451	7	-	28162770	P31FUJ	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.292742086236383	[916]	[1319]	3	hSpCas9	negative selection	11119336
64078098	64078121	7	-	28162770	P31FUJ	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-0.7649128228697999	[602]	[416]	-5	hSpCas9	negative selection	11119337
64069559	64069582	7	+	28162770	OCIAML5	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	1.4422639654593354	[94]	[465]	9	hSpCas9	negative selection	11288694
64078176	64078199	7	-	28162770	OCIAML5	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	0.8636705298931819	[266]	[876]	7	hSpCas9	negative selection	11288695
64068887	64068910	7	+	28162770	OCIAML5	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.7286339030029996	[225]	[675]	6	hSpCas9	negative selection	11288696
64077388	64077411	7	+	28162770	OCIAML5	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	0.8836758820327683	[117]	[392]	7	hSpCas9	negative selection	11288697
64078511	64078534	7	-	28162770	OCIAML5	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	0.20526660420195458	[73]	[153]	1	hSpCas9	negative selection	11288698
64077400	64077423	7	-	28162770	OCIAML5	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	0.33826464124015254	[194]	[444]	3	hSpCas9	negative selection	11288699
64077768	64077791	7	-	28162770	OCIAML5	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	0.5040772393612782	[274]	[703]	4	hSpCas9	negative selection	11288700
64069588	64069611	7	+	28162770	OCIAML5	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-0.24083841544903511	[126]	[193]	-2	hSpCas9	negative selection	11288701
64078428	64078451	7	-	28162770	OCIAML5	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.6995311110587392	[451]	[1324]	6	hSpCas9	negative selection	11288702
64078098	64078121	7	-	28162770	OCIAML5	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-0.20953253945969852	[261]	[408]	-1	hSpCas9	negative selection	11288703
64069559	64069582	7	+	28162770	EOL1	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.4295867279947415	[333]	[236]	4	hSpCas9	negative selection	11458060
64078176	64078199	7	-	28162770	EOL1	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	0.21648521502028173	[592]	[362]	2	hSpCas9	negative selection	11458061
64068887	64068910	7	+	28162770	EOL1	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.9205951799450345	[730]	[728]	7	hSpCas9	negative selection	11458062
64077388	64077411	7	+	28162770	EOL1	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	0.6067475623058489	[348]	[279]	5	hSpCas9	negative selection	11458063
64078511	64078534	7	-	28162770	EOL1	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	0.40064679658565694	[265]	[184]	3	hSpCas9	negative selection	11458064
64077400	64077423	7	-	28162770	EOL1	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	-0.36118177458543543	[550]	[225]	-3	hSpCas9	negative selection	11458065
64077768	64077791	7	-	28162770	EOL1	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	0.5234494632495645	[514]	[389]	5	hSpCas9	negative selection	11458066
64069588	64069611	7	+	28162770	EOL1	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-0.8617455349592398	[237]	[68]	-6	hSpCas9	negative selection	11458067
64078428	64078451	7	-	28162770	EOL1	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.6714288346018236	[782]	[656]	6	hSpCas9	negative selection	11458068
64078098	64078121	7	-	28162770	EOL1	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-0.18691265891800857	[537]	[248]	-1	hSpCas9	negative selection	11458069
64069559	64069582	7	+	28162770	MOLM13	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	1.5720902007640547	[246]	[530]	9	hSpCas9	negative selection	11627426
64078176	64078199	7	-	28162770	MOLM13	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	-0.039905258654117315	[636]	[447]	0	hSpCas9	negative selection	11627427
64068887	64068910	7	+	28162770	MOLM13	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.9787201526885205	[578]	[824]	7	hSpCas9	negative selection	11627428
64077388	64077411	7	+	28162770	MOLM13	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	1.4177983335283557	[336]	[650]	9	hSpCas9	negative selection	11627429
64078511	64078534	7	-	28162770	MOLM13	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	0.7320469443373101	[213]	[256]	5	hSpCas9	negative selection	11627430
64077400	64077423	7	-	28162770	MOLM13	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	-0.18854043387483221	[568]	[360]	-1	hSpCas9	negative selection	11627431
64077768	64077791	7	-	28162770	MOLM13	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	0.7057781392041949	[462]	[545]	5	hSpCas9	negative selection	11627432
64069588	64069611	7	+	28162770	MOLM13	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	-1.6264380010035744	[315]	[73]	-7	hSpCas9	negative selection	11627433
64078428	64078451	7	-	28162770	MOLM13	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.6787861640431971	[863]	[999]	5	hSpCas9	negative selection	11627434
64078098	64078121	7	-	28162770	MOLM13	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-0.9116737687534346	[548]	[210]	-5	hSpCas9	negative selection	11627435
64069559	64069582	7	+	28162770	HEL	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	1.0481076830411677	[261]	[346]	8	hSpCas9	negative selection	11796792
64078176	64078199	7	-	28162770	HEL	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	0.6991213018978757	[551]	[573]	6	hSpCas9	negative selection	11796793
64068887	64068910	7	+	28162770	HEL	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	1.1909895543649918	[596]	[872]	9	hSpCas9	negative selection	11796794
64077388	64077411	7	+	28162770	HEL	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	0.6808320031724314	[298]	[306]	6	hSpCas9	negative selection	11796795
64078511	64078534	7	-	28162770	HEL	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	1.1977065924236756	[161]	[237]	9	hSpCas9	negative selection	11796796
64077400	64077423	7	-	28162770	HEL	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	0.3377103375019359	[487]	[394]	3	hSpCas9	negative selection	11796797
64077768	64077791	7	-	28162770	HEL	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	0.2338066953707003	[392]	[295]	2	hSpCas9	negative selection	11796798
64069588	64069611	7	+	28162770	HEL	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	0.060729648668548145	[243]	[162]	0	hSpCas9	negative selection	11796799
64078428	64078451	7	-	28162770	HEL	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.7512312690912237	[652]	[703]	6	hSpCas9	negative selection	11796800
64078098	64078121	7	-	28162770	HEL	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-0.3301675071173678	[421]	[214]	-2	hSpCas9	negative selection	11796801
64069559	64069582	7	+	28162770	MV411	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	1.4643381686057362	[187]	[436]	9	hSpCas9	negative selection	11966158
64078176	64078199	7	-	28162770	MV411	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	0.7620107236125335	[384]	[549]	7	hSpCas9	negative selection	11966159
64068887	64068910	7	+	28162770	MV411	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.740846113614491	[411]	[579]	6	hSpCas9	negative selection	11966160
64077388	64077411	7	+	28162770	MV411	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	0.44857742289062674	[253]	[291]	4	hSpCas9	negative selection	11966161
64078511	64078534	7	-	28162770	MV411	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	1.067616513197963	[127]	[225]	8	hSpCas9	negative selection	11966162
64077400	64077423	7	-	28162770	MV411	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	-0.029216464340146464	[297]	[245]	0	hSpCas9	negative selection	11966163
64077768	64077791	7	-	28162770	MV411	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	0.7807240167316088	[359]	[520]	7	hSpCas9	negative selection	11966164
64069588	64069611	7	+	28162770	MV411	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	0.7561894848838128	[148]	[211]	6	hSpCas9	negative selection	11966165
64078428	64078451	7	-	28162770	MV411	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.6447246479242006	[551]	[726]	6	hSpCas9	negative selection	11966166
64078098	64078121	7	-	28162770	MV411	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-1.0673484748605673	[402]	[161]	-6	hSpCas9	negative selection	11966167
64069559	64069582	7	+	28162770	MONOMAC1	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	-0.3135508557859789	[115]	[106]	-3	hSpCas9	negative selection	12135524
64078176	64078199	7	-	28162770	MONOMAC1	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	0.4359583500834039	[255]	[396]	4	hSpCas9	negative selection	12135525
64068887	64068910	7	+	28162770	MONOMAC1	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.5443272110041695	[261]	[437]	5	hSpCas9	negative selection	12135526
64077388	64077411	7	+	28162770	MONOMAC1	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	-0.043124163605872234	[150]	[167]	0	hSpCas9	negative selection	12135527
64078511	64078534	7	-	28162770	MONOMAC1	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	0.45290568486928695	[122]	[192]	4	hSpCas9	negative selection	12135528
64077400	64077423	7	-	28162770	MONOMAC1	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	0.4927947715155575	[167]	[270]	5	hSpCas9	negative selection	12135529
64077768	64077791	7	-	28162770	MONOMAC1	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	-0.017091043043245602	[270]	[306]	0	hSpCas9	negative selection	12135530
64069588	64069611	7	+	28162770	MONOMAC1	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	0.2274609814683562	[113]	[152]	2	hSpCas9	negative selection	12135531
64078428	64078451	7	-	28162770	MONOMAC1	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.3167788066974637	[380]	[543]	3	hSpCas9	negative selection	12135532
64078098	64078121	7	-	28162770	MONOMAC1	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-0.6408232848200157	[320]	[235]	-5	hSpCas9	negative selection	12135533
64069559	64069582	7	+	28162770	OCIAML2	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	0.5766758895361954	[44]	[371]	5	hSpCas9	negative selection	12304890
64078176	64078199	7	-	28162770	OCIAML2	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	0.9929594188687921	[62]	[694]	8	hSpCas9	negative selection	12304891
64068887	64068910	7	+	28162770	OCIAML2	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.5439745876666107	[85]	[694]	5	hSpCas9	negative selection	12304892
64077388	64077411	7	+	28162770	OCIAML2	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	0.24034056039110052	[41]	[274]	2	hSpCas9	negative selection	12304893
64078511	64078534	7	-	28162770	OCIAML2	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	0.6549010568416979	[21]	[191]	6	hSpCas9	negative selection	12304894
64077400	64077423	7	-	28162770	OCIAML2	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	0.24503636712358856	[57]	[380]	2	hSpCas9	negative selection	12304895
64077768	64077791	7	-	28162770	OCIAML2	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	1.3427741414882481	[50]	[716]	9	hSpCas9	negative selection	12304896
64069588	64069611	7	+	28162770	OCIAML2	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	0.2640797949836772	[31]	[212]	2	hSpCas9	negative selection	12304897
64078428	64078451	7	-	28162770	OCIAML2	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.23800704586555055	[107]	[705]	2	hSpCas9	negative selection	12304898
64078098	64078121	7	-	28162770	OCIAML2	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	-1.5096239568580248	[74]	[145]	-7	hSpCas9	negative selection	12304899
64069559	64069582	7	+	28162770	OCIAML3	viability	GAAAAGAGCCTTGGAATGCGAGG	ZNF727	ENSG00000214652	-0.037059515772603496	[51]	[152]	0	hSpCas9	negative selection	12474256
64078176	64078199	7	-	28162770	OCIAML3	viability	CAGGTCTGAGAACCACTTAAAGG	ZNF727	ENSG00000214652	0.873771321026654	[93]	[519]	7	hSpCas9	negative selection	12474257
64068887	64068910	7	+	28162770	OCIAML3	viability	TCAGCGAGTGCTAACATTCAGGG	ZNF727	ENSG00000214652	0.4557959155964506	[120]	[500]	4	hSpCas9	negative selection	12474258
64077388	64077411	7	+	28162770	OCIAML3	viability	AAAGAAAGACTACCAACGTGTGG	ZNF727	ENSG00000214652	-0.35380394287125455	[68]	[162]	-3	hSpCas9	negative selection	12474259
64078511	64078534	7	-	28162770	OCIAML3	viability	AAGGTCTGAGAACCACCTAAAGG	ZNF727	ENSG00000214652	0.44701962793589156	[25]	[106]	4	hSpCas9	negative selection	12474260
64077400	64077423	7	-	28162770	OCIAML3	viability	CCTTGCAATTACCCACACGTTGG	ZNF727	ENSG00000214652	-0.40418308144414594	[127]	[291]	-3	hSpCas9	negative selection	12474261
64077768	64077791	7	-	28162770	OCIAML3	viability	CTTGTGTTTAGTAAGGGCTGAGG	ZNF727	ENSG00000214652	0.8149553445449962	[118]	[631]	7	hSpCas9	negative selection	12474262
64069588	64069611	7	+	28162770	OCIAML3	viability	AAGACAGTAGCCAAACACCCAGG	ZNF727	ENSG00000214652	0.707161894396402	[27]	[137]	6	hSpCas9	negative selection	12474263
64078428	64078451	7	-	28162770	OCIAML3	viability	AAGGCTTGAGGAGCAGGTAAAGG	ZNF727	ENSG00000214652	0.42823477003213717	[176]	[718]	4	hSpCas9	negative selection	12474264
64078098	64078121	7	-	28162770	OCIAML3	viability	GCTAATAAGGGTTGAGGAGTAGG	ZNF727	ENSG00000214652	0.7185825899838632	[123]	[615]	6	hSpCas9	negative selection	12474265