Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:162993
• Symbol:ZNF846
• Description:zinc finger protein 846

DataSource: http://genomecrispr.dkfz.de/#!/results/ZNF846

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
9759888	9759911	19	+	26472758	Jiyoye	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	-0.0415098556674276	[534]	[391]	0	hSpCas9	negative selection	190294
9758244	9758267	19	-	26472758	Jiyoye	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	0.2567585389527748	[100]	[90]	2	hSpCas9	negative selection	190295
9762081	9762104	19	-	26472758	Jiyoye	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	0.41226425817867307	[282]	[283]	3	hSpCas9	negative selection	190296
9762102	9762125	19	-	26472758	Jiyoye	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	1.4742895773644102	[62]	[131]	8	hSpCas9	negative selection	190297
9759870	9759893	19	-	26472758	Jiyoye	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.3915785264548549	[185]	[183]	3	hSpCas9	negative selection	190298
9762127	9762150	19	-	26472758	Jiyoye	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	0.29013596031565403	[230]	[212]	2	hSpCas9	negative selection	190299
9758328	9758351	19	-	26472758	Jiyoye	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-1.0655776156292576	[135]	[48]	-6	hSpCas9	negative selection	190300
9758160	9758183	19	-	26472758	Jiyoye	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	-0.7931232689799576	[107]	[46]	-5	hSpCas9	negative selection	190301
9758354	9758377	19	+	26472758	Jiyoye	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.5591784749509235	[233]	[259]	4	hSpCas9	negative selection	190302
9758274	9758297	19	-	26472758	Jiyoye	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	-0.38240483882375453	[120]	[69]	-3	hSpCas9	negative selection	190303
9759888	9759911	19	+	26472758	KBM7	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.5307052868921249	[1250,857]	[741,673]	6	hSpCas9	negative selection	381412
9758244	9758267	19	-	26472758	KBM7	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	0.41844903098209485	[691,834]	[595,388]	4	hSpCas9	negative selection	381413
9762081	9762104	19	-	26472758	KBM7	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	0.43272817741477787	[1080,660]	[610,479]	4	hSpCas9	negative selection	381414
9762102	9762125	19	-	26472758	KBM7	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	0.9244010585289905	[495,341]	[298,430]	8	hSpCas9	negative selection	381415
9759870	9759893	19	-	26472758	KBM7	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.7388410291871788	[823,688]	[636,549]	7	hSpCas9	negative selection	381416
9762127	9762150	19	-	26472758	KBM7	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	0.43426362550795106	[1155,918]	[764,555]	5	hSpCas9	negative selection	381417
9758328	9758351	19	-	26472758	KBM7	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-0.8897469752811832	[436,407]	[109,104]	-6	hSpCas9	negative selection	381418
9758160	9758183	19	-	26472758	KBM7	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	-0.0023339910625906346	[368,323]	[145,176]	0	hSpCas9	negative selection	381419
9758354	9758377	19	+	26472758	KBM7	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.6771363050036725	[1411,1284]	[1006,1019]	7	hSpCas9	negative selection	381420
9758274	9758297	19	-	26472758	KBM7	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	0.7698615652094074	[544,643]	[567,406]	8	hSpCas9	negative selection	381421
9759888	9759911	19	+	26472758	Raji	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.2305317661464643	[605]	[164]	2	hSpCas9	negative selection	572530
9758244	9758267	19	-	26472758	Raji	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	-0.24714922494569053	[357]	[69]	-2	hSpCas9	negative selection	572531
9762081	9762104	19	-	26472758	Raji	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	0.6349818409993269	[418]	[150]	6	hSpCas9	negative selection	572532
9762102	9762125	19	-	26472758	Raji	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	0.2720142371463989	[181]	[50]	2	hSpCas9	negative selection	572533
9759870	9759893	19	-	26472758	Raji	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.32511959427882564	[398]	[115]	3	hSpCas9	negative selection	572534
9762127	9762150	19	-	26472758	Raji	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	0.9418935052716286	[405]	[180]	8	hSpCas9	negative selection	572535
9758328	9758351	19	-	26472758	Raji	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	0.07763619197954738	[195]	[47]	0	hSpCas9	negative selection	572536
9758160	9758183	19	-	26472758	Raji	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	0.6744241280974932	[134]	[49]	6	hSpCas9	negative selection	572537
9758354	9758377	19	+	26472758	Raji	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	-0.06680979770551643	[676]	[149]	0	hSpCas9	negative selection	572538
9758274	9758297	19	-	26472758	Raji	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	-0.6157762592675762	[415]	[62]	-5	hSpCas9	negative selection	572539
9759888	9759911	19	+	26472758	K562	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.8692955979386541	[807]	[1245]	7	hSpCas9	negative selection	763648
9758244	9758267	19	-	26472758	K562	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	0.3304148356226457	[520]	[552]	2	hSpCas9	negative selection	763649
9762081	9762104	19	-	26472758	K562	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	1.0019843353713564	[597]	[1010]	8	hSpCas9	negative selection	763650
9762102	9762125	19	-	26472758	K562	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	0.38731077041174317	[412]	[455]	3	hSpCas9	negative selection	763651
9759870	9759893	19	-	26472758	K562	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	1.0513825164585704	[526]	[921]	8	hSpCas9	negative selection	763652
9762127	9762150	19	-	26472758	K562	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	0.35756931335716313	[906]	[980]	3	hSpCas9	negative selection	763653
9758328	9758351	19	-	26472758	K562	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-1.9890714025533314	[347]	[73]	-7	hSpCas9	negative selection	763654
9758160	9758183	19	-	26472758	K562	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	0.08829952574916511	[233]	[209]	0	hSpCas9	negative selection	763655
9758354	9758377	19	+	26472758	K562	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.8274106024277601	[1220]	[1828]	7	hSpCas9	negative selection	763656
9758274	9758297	19	-	26472758	K562	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	-0.4349361433296641	[449]	[280]	-3	hSpCas9	negative selection	763657
9757754	9757777	19	+	26627737	DLD1	viability	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	-0.5135660930743446	[372]	[53,102,87]	-5	hSpCas9	negative selection	807889
9758343	9758366	19	-	26627737	DLD1	viability	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.46923928211919896	[423]	[201,119,219]	5	hSpCas9	negative selection	807890
9757754	9757777	19	+	26627737	GBM cells	viability after 5 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	0.4389289695528672	[162]	[119,116]	6	hSpCas9	negative selection	890204
9758343	9758366	19	-	26627737	GBM cells	viability after 5 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.5160567813559918	[265]	[185,221]	7	hSpCas9	negative selection	890205
9757754	9757777	19	+	26627737	GBM cells	viability after 13 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	0.9811875047178338	[162]	[253,109]	9	hSpCas9	negative selection	972519
9758343	9758366	19	-	26627737	GBM cells	viability after 13 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.48329813057915944	[265]	[273,142]	6	hSpCas9	negative selection	972520
9757754	9757777	19	+	26627737	GBM cells	viability after 21 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	1.018005007220049	[162]	[194,164]	8	hSpCas9	negative selection	1054834
9758343	9758366	19	-	26627737	GBM cells	viability after 21 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.5861326957014983	[265]	[229,204]	6	hSpCas9	negative selection	1054835
9757754	9757777	19	+	26627737	RPE1	viability after 9 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	1.1094237743516135	[339]	[185,285]	6	hSpCas9	negative selection	1137149
9758343	9758366	19	-	26627737	RPE1	viability after 9 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	-1.1078837623194047	[1570]	[232,221]	-7	hSpCas9	negative selection	1137150
9757754	9757777	19	+	26627737	RPE1	viability after 12 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	0.8140485581653882	[339]	[163,156]	5	hSpCas9	negative selection	1219464
9758343	9758366	19	-	26627737	RPE1	viability after 12 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	-0.8767623649552165	[1570]	[275,180]	-6	hSpCas9	negative selection	1219465
9757754	9757777	19	+	26627737	RPE1	viability after 15 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	0.10116994388617195	[339]	[121,84]	0	hSpCas9	negative selection	1301779
9758343	9758366	19	-	26627737	RPE1	viability after 15 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	-1.137894964674516	[1570]	[204,198]	-6	hSpCas9	negative selection	1301780
9757754	9757777	19	+	26627737	RPE1	viability after 18 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	0.7027918368698987	[339]	[173,122]	4	hSpCas9	negative selection	1384094
9758343	9758366	19	-	26627737	RPE1	viability after 18 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	-1.0092947341046261	[1570]	[184,237]	-6	hSpCas9	negative selection	1384095
9757754	9757777	19	+	26627737	HeLa	viability after 8 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	1.0128090620623094	[139]	[274,59,70]	7	hSpCas9	negative selection	1466409
9758343	9758366	19	-	26627737	HeLa	viability after 8 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.0941868851472861	[450]	[316,197,141]	0	hSpCas9	negative selection	1466410
9757754	9757777	19	+	26627737	HeLa	viability after 12 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	1.191611556981659	[139]	[98,98,200]	8	hSpCas9	negative selection	1548724
9758343	9758366	19	-	26627737	HeLa	viability after 12 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	-0.07656856480065313	[450]	[129,203,191]	0	hSpCas9	negative selection	1548725
9757754	9757777	19	+	26627737	HeLa	viability after 15 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	0.7377709000232079	[139]	[114,24,148]	6	hSpCas9	negative selection	1631039
9758343	9758366	19	-	26627737	HeLa	viability after 15 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	-0.00826039296491149	[450]	[146,207,193]	0	hSpCas9	negative selection	1631040
9757754	9757777	19	+	26627737	HeLa	viability after 18 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	0.7195376861656034	[139]	[76,17,148]	5	hSpCas9	negative selection	1713354
9758343	9758366	19	-	26627737	HeLa	viability after 18 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.009443117335367679	[450]	[99,175,193]	0	hSpCas9	negative selection	1713355
9757754	9757777	19	+	26627737	HCT116	viability after 6 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	-0.4416406801867535	[450]	[28,64]	-3	hSpCas9	negative selection	1795669
9758343	9758366	19	-	26627737	HCT116	viability after 6 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	1.2183183620121314	[693]	[608,57]	6	hSpCas9	negative selection	1795670
9757754	9757777	19	+	26627737	HCT116	viability after 8 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	0.014174930963105847	[211]	[160,101,91]	0	hSpCas9	negative selection	1877984
9758343	9758366	19	-	26627737	HCT116	viability after 8 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.25047002215646114	[280]	[218,132,200]	3	hSpCas9	negative selection	1877985
9757754	9757777	19	+	26627737	HCT116	viability after 9 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	0.5555383055065017	[450]	[95,240]	4	hSpCas9	negative selection	1960299
9758343	9758366	19	-	26627737	HCT116	viability after 9 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	-0.0812546881352613	[693]	[330,51]	0	hSpCas9	negative selection	1960300
9757754	9757777	19	+	26627737	HCT116	viability after 12 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	-0.1536173616968768	[211]	[97,113,88]	-1	hSpCas9	negative selection	2042614
9758343	9758366	19	-	26627737	HCT116	viability after 12 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.1348856997180275	[280]	[213,166,100]	1	hSpCas9	negative selection	2042615
9757754	9757777	19	+	26627737	HCT116	viability after 15 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	-0.21940399666053478	[211]	[152,93,72]	-2	hSpCas9	negative selection	2124929
9758343	9758366	19	-	26627737	HCT116	viability after 15 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.12858342432315034	[280]	[299,125,118]	1	hSpCas9	negative selection	2124930
9757754	9757777	19	+	26627737	HCT116	viability after 18 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	0.04119082881162428	[211]	[172,80,61]	0	hSpCas9	negative selection	2207244
9758343	9758366	19	-	26627737	HCT116	viability after 18 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.03601939704756033	[280]	[130,149,135]	0	hSpCas9	negative selection	2207245
9768852	9768875	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGTACGCGTGTCGAAGAGGTGG	ZNF846	ENSG00000196605	-0.5990948637207536	[0,51]	[2,3]	-3	dCas9-VP64	positive selection	2392902
9768897	9768920	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GATCTGGATCCTGGTCCACCTGG	ZNF846	ENSG00000196605	0.7434571217290649	[504,252]	[141,135]	3	dCas9-VP64	positive selection	2392903
9768879	9768902	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTCCCGTTTTCTCGCATCCCAGG	ZNF846	ENSG00000196605	-0.1353952711266619	[69,145]	[11,31]	0	dCas9-VP64	positive selection	2392904
9769476	9769499	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGCACTTTGGGAGGCCAAGGTGG	ZNF846	ENSG00000196605	0.21234444010885142	[57,122]	[21,23]	1	dCas9-VP64	positive selection	2422549
9752011	9752034	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCCTGTAATCCCAGCACTTCGG	ZNF846	ENSG00000196605	-1.262579619046977	[170,274]	[19,19]	-7	dCas9-VP64	positive selection	2446330
9781851	9781874	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTACAACCTCCGCCTCCGGG	ZNF846	ENSG00000196605	-1.3762222380081446	[352,174]	[18,24]	-7	dCas9-VP64	positive selection	2454243
9768852	9768875	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGTACGCGTGTCGAAGAGGTGG	ZNF846	ENSG00000196605	0.03284768271455096	[13,26]	[6,5]	0	dCas9-VP64	positive selection	2488157
9768897	9768920	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GATCTGGATCCTGGTCCACCTGG	ZNF846	ENSG00000196605	3.232373656404069	[131,256]	[262,906]	9	dCas9-VP64	positive selection	2488158
9768879	9768902	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTCCCGTTTTCTCGCATCCCAGG	ZNF846	ENSG00000196605	-0.5737339188504187	[130,209]	[36,36]	-6	dCas9-VP64	positive selection	2488159
9769476	9769499	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGCACTTTGGGAGGCCAAGGTGG	ZNF846	ENSG00000196605	-0.9329704115466368	[100,219]	[26,25]	-8	dCas9-VP64	positive selection	2517804
9752011	9752034	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCCTGTAATCCCAGCACTTCGG	ZNF846	ENSG00000196605	0.31922581039074327	[700,765]	[259,334]	2	dCas9-VP64	positive selection	2541585
9781851	9781874	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTACAACCTCCGCCTCCGGG	ZNF846	ENSG00000196605	-1.0610924962734893	[123,419]	[26,55]	-8	dCas9-VP64	positive selection	2549498
9758328	9758351	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	0.1295070119918769	[2,3]	[3,2]	2	hSpCas9	positive selection	3035554
9762081	9762104	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	0.08988921385765353	[4,5]	[4,4]	1	hSpCas9	positive selection	3035555
9759870	9759893	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.22411128494060367	[5,4]	[4,5]	5	hSpCas9	positive selection	3035556
9758412	9758435	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACATATAAGATCTCACAATGG	ZNF846	ENSG00000196605	-0.20225679444649775	[3,3]	[4,0]	-3	hSpCas9	positive selection	3035557
9758328	9758351	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	0.5326749532602575	[2,2]	[3,2]	8	hSpCas9	positive selection	3103412
9762081	9762104	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	-0.06690426256657972	[4,4]	[4,2]	-1	hSpCas9	positive selection	3103413
9759870	9759893	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.13352706073410087	[5,5]	[4,3]	2	hSpCas9	positive selection	3103414
9758412	9758435	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACATATAAGATCTCACAATGG	ZNF846	ENSG00000196605	-0.44549095057256116	[3,3]	[3,0]	-6	hSpCas9	positive selection	3103415
9764935	9764958		-	24336571	A375	resistance to PLX after 7 days	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.09017270163154195	[9,8]	[8,11]	3	hSpCas9	positive selection	3158338
9763318	9763341		+	24336571	A375	resistance to PLX after 7 days	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	-0.2950248922176065	[7,7]	[6,5]	-8	hSpCas9	positive selection	3158339
9763390	9763413		-	24336571	A375	resistance to PLX after 7 days	TTAGCACTTAGTGACCTTTGAGG	ZNF846	ENSG00000196605	0.09565459418387676	[9,10]	[10,10]	3	hSpCas9	positive selection	3158340
9764935	9764958		-	24336571	A375	resistance to PLX after 14 days	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.2654951213273432	[8,9]	[4,4]	2	hSpCas9	positive selection	3216131
9763318	9763341		+	24336571	A375	resistance to PLX after 14 days	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.2547576748057193	[4,6]	[2,2]	2	hSpCas9	positive selection	3216132
9763390	9763413		-	24336571	A375	resistance to PLX after 14 days	TTAGCACTTAGTGACCTTTGAGG	ZNF846	ENSG00000196605	-0.09361316531618108	[11,7]	[4,2]	-1	hSpCas9	positive selection	3216133
9764935	9764958		-	24336571	A375	viability after 7 days	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.8034651707013961	[17]	[9,8]	-8	hSpCas9	negative selection	3273924
9763318	9763341		+	24336571	A375	viability after 7 days	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.13485043739785874	[7]	[7,7]	2	hSpCas9	negative selection	3273925
9763390	9763413		-	24336571	A375	viability after 7 days	TTAGCACTTAGTGACCTTTGAGG	ZNF846	ENSG00000196605	0.8247756110290057	[5]	[9,10]	9	hSpCas9	negative selection	3273926
9764935	9764958		-	24336571	A375	viability after 14 days	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.7553000229508411	[17]	[8,9]	-7	hSpCas9	negative selection	3331717
9763318	9763341		+	24336571	A375	viability after 14 days	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	-0.14457936577518038	[7]	[4,6]	-2	hSpCas9	negative selection	3331718
9763390	9763413		-	24336571	A375	viability after 14 days	TTAGCACTTAGTGACCTTTGAGG	ZNF846	ENSG00000196605	0.7663050975254393	[5]	[11,7]	8	hSpCas9	negative selection	3331719
9764935	9764958	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.9618423090163265	[297,297]	[0,0]	-6	hSpCas9	positive selection	3403697
9762082	9762105	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.16986337019549572	[135,135]	[0,0]	0	hSpCas9	positive selection	3403698
9759888	9759911	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	-0.6068599332084452	[232,232]	[0,0]	-4	hSpCas9	positive selection	3403699
9758328	9758351	19	-	26780180	HT29	viability (Avana library 4 designs)	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	1.11070792454803	[]	[]	4	hSpCas9	negative selection	3474908
9762081	9762104	19	-	26780180	HT29	viability (Avana library 4 designs)	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	-0.166055643226481	[]	[]	-3	hSpCas9	negative selection	3474909
9759870	9759893	19	-	26780180	HT29	viability (Avana library 4 designs)	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	-0.580613627677046	[]	[]	-8	hSpCas9	negative selection	3474910
9758412	9758435	19	-	26780180	HT29	viability (Avana library 4 designs)	TTACATATAAGATCTCACAATGG	ZNF846	ENSG00000196605	2.11475185140482	[]	[]	7	hSpCas9	negative selection	3474911
9762081	9762104	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	4.80726976711881	[]	[]	7	hSpCas9	negative selection	3583431
9758328	9758351	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-4.69083802432821	[]	[]	-5	hSpCas9	negative selection	3583432
9758412	9758435	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTACATATAAGATCTCACAATGG	ZNF846	ENSG00000196605	-25.3461011025298	[]	[]	-9	hSpCas9	negative selection	3583433
9759870	9759893	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	-3.02638655024133	[]	[]	-4	hSpCas9	negative selection	3583434
9758664	9758687	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTCACATGATAACTCACATTGG	ZNF846	ENSG00000196605	-4.58355195348228	[]	[]	-5	hSpCas9	negative selection	3583435
9758647	9758670	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATTGGAGAGAAAACTTCTGAGG	ZNF846	ENSG00000196605	2.28231504846418	[]	[]	3	hSpCas9	negative selection	3583436
9762081	9762104	19	-	26780180	A375	viability (Avana lentiGuide)	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	-3.90991887408458	[]	[]	-6	hSpCas9	negative selection	3692090
9758328	9758351	19	-	26780180	A375	viability (Avana lentiGuide)	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-0.443478372559841	[]	[]	0	hSpCas9	negative selection	3692091
9758412	9758435	19	-	26780180	A375	viability (Avana lentiGuide)	TTACATATAAGATCTCACAATGG	ZNF846	ENSG00000196605	-1.40993769917787	[]	[]	-2	hSpCas9	negative selection	3692092
9759870	9759893	19	-	26780180	A375	viability (Avana lentiGuide)	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	-7.08107763544764	[]	[]	-9	hSpCas9	negative selection	3692093
9758664	9758687	19	-	26780180	A375	viability (Avana lentiGuide)	ACTCACATGATAACTCACATTGG	ZNF846	ENSG00000196605	1.79362081958715	[]	[]	2	hSpCas9	negative selection	3692094
9758647	9758670	19	-	26780180	A375	viability (Avana lentiGuide)	CATTGGAGAGAAAACTTCTGAGG	ZNF846	ENSG00000196605	-3.84590484455911	[]	[]	-6	hSpCas9	negative selection	3692095
9762081	9762104	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	0.23364642949507078	[5]	[7,6]	6	hSpCas9	positive selection	3800697
9758328	9758351	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-0.4159409124460971	[4]	[3,2]	-6	hSpCas9	positive selection	3800698
9758412	9758435	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACATATAAGATCTCACAATGG	ZNF846	ENSG00000196605	-1.3995921088072367	[9]	[1,3]	-9	hSpCas9	positive selection	3800699
9759870	9759893	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	-0.36965167023531076	[6]	[5,4]	-5	hSpCas9	positive selection	3800700
9758664	9758687	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTCACATGATAACTCACATTGG	ZNF846	ENSG00000196605	-0.28511018413141787	[7]	[5,4]	-4	hSpCas9	positive selection	3800701
9758647	9758670	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTGGAGAGAAAACTTCTGAGG	ZNF846	ENSG00000196605	0.11226810557365291	[6]	[6,6]	3	hSpCas9	positive selection	3800702
9762081	9762104	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	0.33428039833582984	[6]	[7,6]	8	hSpCas9	positive selection	3909304
9758328	9758351	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-0.7472074734275338	[4]	[1,2]	-7	hSpCas9	positive selection	3909305
9758412	9758435	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACATATAAGATCTCACAATGG	ZNF846	ENSG00000196605	-0.3940978942693266	[5]	[2,3]	-5	hSpCas9	positive selection	3909306
9759870	9759893	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.39359497936680576	[6]	[7,7]	9	hSpCas9	positive selection	3909307
9758664	9758687	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTCACATGATAACTCACATTGG	ZNF846	ENSG00000196605	0.1456136568781431	[6]	[6,6]	3	hSpCas9	positive selection	3909308
9758647	9758670	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTGGAGAGAAAACTTCTGAGG	ZNF846	ENSG00000196605	0.29017364909551446	[6]	[7,6]	7	hSpCas9	positive selection	3909309
9762082	9762105	19	-	26780180	A375	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	1.79207932323496	[]	[]	9	hSpCas9	negative selection	4017250
9764935	9764958	19	-	26780180	A375	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	1.03498651994472	[]	[]	5	hSpCas9	negative selection	4017251
9763318	9763341	19	+	26780180	A375	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.58937361445939	[]	[]	1	hSpCas9	negative selection	4017252
9759855	9759878	19	+	26780180	A375	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	-0.483295068373199	[]	[]	-9	hSpCas9	negative selection	4017253
9759888	9759911	19	+	26780180	A375	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	1.54429284928448	[]	[]	8	hSpCas9	negative selection	4017254
9762132	9762155	19	-	26780180	A375	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.656430661130125	[]	[]	2	hSpCas9	negative selection	4017255
9762082	9762105	19	-	26780180	HT29	viability (GeCKOv2 library)	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	1.94314987232119	[]	[]	9	hSpCas9	negative selection	4125216
9764935	9764958	19	-	26780180	HT29	viability (GeCKOv2 library)	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.913255663894655	[]	[]	4	hSpCas9	negative selection	4125217
9763318	9763341	19	+	26780180	HT29	viability (GeCKOv2 library)	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.715024105356775	[]	[]	2	hSpCas9	negative selection	4125218
9759855	9759878	19	+	26780180	HT29	viability (GeCKOv2 library)	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	-0.470848871969198	[]	[]	-9	hSpCas9	negative selection	4125219
9759888	9759911	19	+	26780180	HT29	viability (GeCKOv2 library)	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	1.26893676238509	[]	[]	6	hSpCas9	negative selection	4125220
9762132	9762155	19	-	26780180	HT29	viability (GeCKOv2 library)	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	1.14557046970182	[]	[]	5	hSpCas9	negative selection	4125221
9764935	9764958	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.11438673824431309	[3]	[1,2]	-3	hSpCas9	positive selection	4185591
9763318	9763341	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.01870666303413726	[2]	[1,1]	0	hSpCas9	positive selection	4185592
9763390	9763413	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTAGCACTTAGTGACCTTTGAGG	ZNF846	ENSG00000196605	-0.17264460314144958	[4]	[3,1]	-4	hSpCas9	positive selection	4185593
9764935	9764958	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	1.1117595132899947	[4]	[3,3,1,5]	8	hSpCas9	positive selection	4249613
9763318	9763341	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	-0.3854776615349301	[2]	[0,0,0,0]	-5	hSpCas9	positive selection	4249614
9763390	9763413	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTAGCACTTAGTGACCTTTGAGG	ZNF846	ENSG00000196605	0.9055113514198991	[4]	[3,4,3,3]	6	hSpCas9	positive selection	4249615
9759855	9759878	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.5104095462501166	[4]	[5,4]	9	hSpCas9	positive selection	4310480
9763318	9763341	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.003349400360736665	[2]	[1,1]	0	hSpCas9	positive selection	4310481
9762132	9762155	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.1691176960985381	[4]	[3,3]	3	hSpCas9	positive selection	4310482
9764935	9764958	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.05624132848697394	[3]	[3,1]	-1	hSpCas9	positive selection	4374727
9762082	9762105	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.47352385076914055	[2]	[1,0]	-8	hSpCas9	positive selection	4374728
9759888	9759911	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.48779440154081405	[2]	[3,2]	8	hSpCas9	positive selection	4374729
9758343	9758365	19	-	27760321	OCIAML3	viability	CCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.4870851195165635	[456,379]	[270,698]	6	hSpCas9	negative selection	4458054
9758677	9758699	19	+	27760321	OCIAML3	viability	TCATGTGAGTCATAAGAAATGG	ZNF846	ENSG00000196605	-3.7624510926589343	[19,14]	[0,0]	-9	hSpCas9	negative selection	4458055
9759859	9759881	19	-	27760321	OCIAML3	viability	TCACCAAATGGAGTACAATTGG	ZNF846	ENSG00000196605	0.1011855308887264	[136,87]	[92,92]	1	hSpCas9	negative selection	4458056
9759891	9759913	19	+	27760321	OCIAML3	viability	GAAATATCTTGCAGCAGTGGGG	ZNF846	ENSG00000196605	0.8444302452598436	[673,609]	[813,1013]	8	hSpCas9	negative selection	4458057
9762102	9762124	19	-	27760321	OCIAML3	viability	AAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	0.12098328757200696	[406,305]	[258,354]	1	hSpCas9	negative selection	4458058
9758343	9758365	19	-	27760321	OCIAML2	viability	CCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.767159266510339	[456,379]	[467,712]	9	hSpCas9	negative selection	4541517
9758677	9758699	19	+	27760321	OCIAML2	viability	TCATGTGAGTCATAAGAAATGG	ZNF846	ENSG00000196605	-3.811196457923983	[19,14]	[0,0]	-9	hSpCas9	negative selection	4541518
9759859	9759881	19	-	27760321	OCIAML2	viability	TCACCAAATGGAGTACAATTGG	ZNF846	ENSG00000196605	0.415575148293714	[136,87]	[91,155]	5	hSpCas9	negative selection	4541519
9759891	9759913	19	+	27760321	OCIAML2	viability	GAAATATCTTGCAGCAGTGGGG	ZNF846	ENSG00000196605	0.18678428903410071	[673,609]	[493,717]	2	hSpCas9	negative selection	4541520
9762102	9762124	19	-	27760321	OCIAML2	viability	AAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	0.06654694258847138	[406,305]	[248,365]	0	hSpCas9	negative selection	4541521
9758343	9758365	19	-	27760321	MV411	viability	CCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.46536689116708085	[456,379]	[222,614]	3	hSpCas9	negative selection	4624980
9758677	9758699	19	+	27760321	MV411	viability	TCATGTGAGTCATAAGAAATGG	ZNF846	ENSG00000196605	-3.5173725237442524	[19,14]	[0,0]	-9	hSpCas9	negative selection	4624981
9759859	9759881	19	-	27760321	MV411	viability	TCACCAAATGGAGTACAATTGG	ZNF846	ENSG00000196605	-1.3060809083970413	[136,87]	[11,55]	-7	hSpCas9	negative selection	4624982
9759891	9759913	19	+	27760321	MV411	viability	GAAATATCTTGCAGCAGTGGGG	ZNF846	ENSG00000196605	0.48440132827282967	[673,609]	[614,557]	3	hSpCas9	negative selection	4624983
9762102	9762124	19	-	27760321	MV411	viability	AAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-1.2849969237612644	[406,305]	[18,210]	-7	hSpCas9	negative selection	4624984
9758343	9758365	19	-	27760321	HL60	viability	CCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	1.1025230952397898	[456,379]	[662,802]	9	hSpCas9	negative selection	4708443
9758677	9758699	19	+	27760321	HL60	viability	TCATGTGAGTCATAAGAAATGG	ZNF846	ENSG00000196605	-1.2687286144466023	[19,14]	[1,9]	-8	hSpCas9	negative selection	4708444
9759859	9759881	19	-	27760321	HL60	viability	TCACCAAATGGAGTACAATTGG	ZNF846	ENSG00000196605	-0.041539054852800295	[136,87]	[70,105]	0	hSpCas9	negative selection	4708445
9759891	9759913	19	+	27760321	HL60	viability	GAAATATCTTGCAGCAGTGGGG	ZNF846	ENSG00000196605	0.39212466532784773	[673,609]	[477,909]	5	hSpCas9	negative selection	4708446
9762102	9762124	19	-	27760321	HL60	viability	AAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.3878721924867707	[406,305]	[210,230]	-4	hSpCas9	negative selection	4708447
9758343	9758365	19	-	27760321	HT1080	viability	CCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	1.6979373429391633	[379,296]	[353,528]	8	hSpCas9	negative selection	4791906
9758677	9758699	19	+	27760321	HT1080	viability	TCATGTGAGTCATAAGAAATGG	ZNF846	ENSG00000196605	-2.429279739642115	[14,11]	[0,0]	-7	hSpCas9	negative selection	4791907
9759859	9759881	19	-	27760321	HT1080	viability	TCACCAAATGGAGTACAATTGG	ZNF846	ENSG00000196605	0.32088861439455263	[87,68]	[8,71]	1	hSpCas9	negative selection	4791908
9759891	9759913	19	+	27760321	HT1080	viability	GAAATATCTTGCAGCAGTGGGG	ZNF846	ENSG00000196605	0.22889587131240996	[609,475]	[221,287]	1	hSpCas9	negative selection	4791909
9762102	9762124	19	-	27760321	HT1080	viability	AAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-3.4770886349949617	[305,238]	[14,3]	-7	hSpCas9	negative selection	4791910
9758343	9758365	19	-	27760321	HT29	viability after 7 days	CCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.3445851916893649	[379,296]	[614,462,586]	5	hSpCas9	negative selection	4875369
9758677	9758699	19	+	27760321	HT29	viability after 7 days	TCATGTGAGTCATAAGAAATGG	ZNF846	ENSG00000196605	0.16234333706384696	[14,11]	[61,1,0]	2	hSpCas9	negative selection	4875370
9759859	9759881	19	-	27760321	HT29	viability after 7 days	TCACCAAATGGAGTACAATTGG	ZNF846	ENSG00000196605	-0.462978759250845	[87,68]	[118,60,46]	-6	hSpCas9	negative selection	4875371
9759891	9759913	19	+	27760321	HT29	viability after 7 days	GAAATATCTTGCAGCAGTGGGG	ZNF846	ENSG00000196605	-0.5536447003553051	[609,475]	[579,572,293]	-7	hSpCas9	negative selection	4875372
9762102	9762124	19	-	27760321	HT29	viability after 7 days	AAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	0.07564793091076327	[305,238]	[464,323,332]	1	hSpCas9	negative selection	4875373
9758343	9758365	19	-	27760321	HT29	viability after 25 days	CCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	1.1609322523278782	[379,296]	[901,682,1022]	9	hSpCas9	negative selection	4958832
9758677	9758699	19	+	27760321	HT29	viability after 25 days	TCATGTGAGTCATAAGAAATGG	ZNF846	ENSG00000196605	-1.3373552709637462	[14,11]	[2,13,0]	-7	hSpCas9	negative selection	4958833
9759859	9759881	19	-	27760321	HT29	viability after 25 days	TCACCAAATGGAGTACAATTGG	ZNF846	ENSG00000196605	0.5844307082167564	[87,68]	[121,192,83]	6	hSpCas9	negative selection	4958834
9759891	9759913	19	+	27760321	HT29	viability after 25 days	GAAATATCTTGCAGCAGTGGGG	ZNF846	ENSG00000196605	-0.06939898753958551	[609,475]	[368,777,645]	0	hSpCas9	negative selection	4958835
9762102	9762124	19	-	27760321	HT29	viability after 25 days	AAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.5102074537599459	[305,238]	[268,237,136]	-5	hSpCas9	negative selection	4958836
9758343	9758365	19	-	27760321	HT29	viability after 22 days	CCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	1.075229494916395	[379,296]	[726,761,988]	9	hSpCas9	negative selection	5042295
9758677	9758699	19	+	27760321	HT29	viability after 22 days	TCATGTGAGTCATAAGAAATGG	ZNF846	ENSG00000196605	-1.3776585797284788	[14,11]	[6,6,3]	-7	hSpCas9	negative selection	5042296
9759859	9759881	19	-	27760321	HT29	viability after 22 days	TCACCAAATGGAGTACAATTGG	ZNF846	ENSG00000196605	0.44597168033344636	[87,68]	[116,145,107]	5	hSpCas9	negative selection	5042297
9759891	9759913	19	+	27760321	HT29	viability after 22 days	GAAATATCTTGCAGCAGTGGGG	ZNF846	ENSG00000196605	0.02586685742356465	[609,475]	[805,646,457]	0	hSpCas9	negative selection	5042298
9762102	9762124	19	-	27760321	HT29	viability after 22 days	AAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.5539113210840494	[305,238]	[190,281,170]	-5	hSpCas9	negative selection	5042299
9758343	9758365	19	-	27760321	HT29	viability after 19 days	CCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	1.32339675277393	[379,296]	[718,1274,888]	9	hSpCas9	negative selection	5125758
9758677	9758699	19	+	27760321	HT29	viability after 19 days	TCATGTGAGTCATAAGAAATGG	ZNF846	ENSG00000196605	-1.7246443784826768	[14,11]	[2,9,0]	-7	hSpCas9	negative selection	5125759
9759859	9759881	19	-	27760321	HT29	viability after 19 days	TCACCAAATGGAGTACAATTGG	ZNF846	ENSG00000196605	0.8252115565425806	[87,68]	[155,190,130]	8	hSpCas9	negative selection	5125760
9759891	9759913	19	+	27760321	HT29	viability after 19 days	GAAATATCTTGCAGCAGTGGGG	ZNF846	ENSG00000196605	-0.10608423389610727	[609,475]	[508,437,768]	-1	hSpCas9	negative selection	5125761
9762102	9762124	19	-	27760321	HT29	viability after 19 days	AAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	0.01738291931611441	[305,238]	[349,210,385]	0	hSpCas9	negative selection	5125762
9758343	9758365	19	-	27760321	HT29	viability after 16 days	CCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.6879021246129505	[379,296]	[673,508,655]	7	hSpCas9	negative selection	5209221
9758677	9758699	19	+	27760321	HT29	viability after 16 days	TCATGTGAGTCATAAGAAATGG	ZNF846	ENSG00000196605	-3.160998583021895	[14,11]	[0,1,1]	-9	hSpCas9	negative selection	5209222
9759859	9759881	19	-	27760321	HT29	viability after 16 days	TCACCAAATGGAGTACAATTGG	ZNF846	ENSG00000196605	0.6018613669879807	[87,68]	[55,196,137]	7	hSpCas9	negative selection	5209223
9759891	9759913	19	+	27760321	HT29	viability after 16 days	GAAATATCTTGCAGCAGTGGGG	ZNF846	ENSG00000196605	0.02152993136791237	[609,475]	[637,571,642]	0	hSpCas9	negative selection	5209224
9762102	9762124	19	-	27760321	HT29	viability after 16 days	AAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.3528384573080043	[305,238]	[162,392,148]	-4	hSpCas9	negative selection	5209225
9758343	9758365	19	-	27760321	HT29	viability after 13 days	CCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.7353033209944478	[379,296]	[657,610,689]	8	hSpCas9	negative selection	5292684
9758677	9758699	19	+	27760321	HT29	viability after 13 days	TCATGTGAGTCATAAGAAATGG	ZNF846	ENSG00000196605	-1.578652688115402	[14,11]	[12,1,0]	-8	hSpCas9	negative selection	5292685
9759859	9759881	19	-	27760321	HT29	viability after 13 days	TCACCAAATGGAGTACAATTGG	ZNF846	ENSG00000196605	0.15516998566210116	[87,68]	[27,149,124]	2	hSpCas9	negative selection	5292686
9759891	9759913	19	+	27760321	HT29	viability after 13 days	GAAATATCTTGCAGCAGTGGGG	ZNF846	ENSG00000196605	0.01832526213671981	[609,475]	[556,837,525]	0	hSpCas9	negative selection	5292687
9762102	9762124	19	-	27760321	HT29	viability after 13 days	AAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.33735561802577435	[305,238]	[233,203,308]	-4	hSpCas9	negative selection	5292688
9758343	9758365	19	-	27760321	HT29	viability after 10 days	CCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.7082467629002619	[379,296]	[789,593,684]	8	hSpCas9	negative selection	5376147
9758677	9758699	19	+	27760321	HT29	viability after 10 days	TCATGTGAGTCATAAGAAATGG	ZNF846	ENSG00000196605	-1.675480147846466	[14,11]	[7,6,0]	-8	hSpCas9	negative selection	5376148
9759859	9759881	19	-	27760321	HT29	viability after 10 days	TCACCAAATGGAGTACAATTGG	ZNF846	ENSG00000196605	0.048870287784544164	[87,68]	[207,48,46]	0	hSpCas9	negative selection	5376149
9759891	9759913	19	+	27760321	HT29	viability after 10 days	GAAATATCTTGCAGCAGTGGGG	ZNF846	ENSG00000196605	0.003492300946598914	[609,475]	[648,939,461]	0	hSpCas9	negative selection	5376150
9762102	9762124	19	-	27760321	HT29	viability after 10 days	AAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.5929038668115751	[305,238]	[207,218,248]	-6	hSpCas9	negative selection	5376151
9758343	9758365	19	-	27760321	MOLM13	viability	CCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	1.5118070720243868	[456,379]	[502,812]	9	hSpCas9	negative selection	5459610
9758677	9758699	19	+	27760321	MOLM13	viability	TCATGTGAGTCATAAGAAATGG	ZNF846	ENSG00000196605	-3.291315710916657	[19,14]	[0,0]	-9	hSpCas9	negative selection	5459611
9759859	9759881	19	-	27760321	MOLM13	viability	TCACCAAATGGAGTACAATTGG	ZNF846	ENSG00000196605	-0.7969128970347157	[136,87]	[35,35]	-5	hSpCas9	negative selection	5459612
9759891	9759913	19	+	27760321	MOLM13	viability	GAAATATCTTGCAGCAGTGGGG	ZNF846	ENSG00000196605	-0.022184822778675284	[673,609]	[498,234]	0	hSpCas9	negative selection	5459613
9762102	9762124	19	-	27760321	MOLM13	viability	AAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.5976708260604096	[406,305]	[46,203]	-4	hSpCas9	negative selection	5459614
9768489	9768512	19	+	27661255	K562	viability	GAAGAGGCGCTCAGAAGAGAAGG	ZNF846	ENSG00000196605	0.005849438935267931	[816,750]	[747,528]	0	dCas9-KRAB	negative selection	5525882
9768524	9768547	19	+	27661255	K562	viability	GCCTCGGGGTCCTGGCGGGGAGG	ZNF846	ENSG00000196605	-0.0975533190782999	[457,485]	[351,351]	-4	dCas9-KRAB	negative selection	5525883
9768541	9768564	19	+	27661255	K562	viability	GGGAGGAGGCGCCGCTTCTCCGG	ZNF846	ENSG00000196605	0.2012112682712493	[890,1128]	[989,866]	7	dCas9-KRAB	negative selection	5525884
9759855	9759878	19	+	27260156	BXPC3	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.3967860383506139	[1149]	[1406,1500,1760,1692]	8	hSpCas9	negative selection	5582940
9763318	9763341	19	+	27260156	BXPC3	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.10978190960904177	[216]	[224,190,202,379]	2	hSpCas9	negative selection	5582941
9762132	9762155	19	-	27260156	BXPC3	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.15662228633953146	[1149]	[1051,962,1098,1220]	-4	hSpCas9	negative selection	5582942
9764935	9764958	19	-	27260156	BXPC3	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.04350279636136911	[774]	[658,742,865,903]	-1	hSpCas9	negative selection	5647187
9762082	9762105	19	-	27260156	BXPC3	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.07365132934836127	[308]	[380,310,342,316]	1	hSpCas9	negative selection	5647188
9759888	9759911	19	+	27260156	BXPC3	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.21543788587408325	[362]	[481,390,394,495]	5	hSpCas9	negative selection	5647189
9759855	9759878	19	+	27260156	A673	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.2696211744522956	[1149]	[1750,1642,1593,1678]	6	hSpCas9	negative selection	5704191
9763318	9763341	19	+	27260156	A673	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.44492497322436986	[216]	[382,301,344,394]	8	hSpCas9	negative selection	5704192
9762132	9762155	19	-	27260156	A673	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.153676301792943	[1149]	[1348,1113,1145,1377]	-4	hSpCas9	negative selection	5704193
9764935	9764958	19	-	27260156	A673	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.07467739158451336	[774]	[1107,956,848,1022]	1	hSpCas9	negative selection	5768438
9762082	9762105	19	-	27260156	A673	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.1913082498425831	[308]	[428,249,385,242]	-5	hSpCas9	negative selection	5768439
9759888	9759911	19	+	27260156	A673	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.04687178502300238	[362]	[427,417,456,497]	1	hSpCas9	negative selection	5768440
9759855	9759878	19	+	27260156	A375	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.5571816068393163	[1149]	[2304,2061,1891,1687]	7	hSpCas9	negative selection	5825442
9763318	9763341	19	+	27260156	A375	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.6802047020961866	[216]	[402,404,447,370]	8	hSpCas9	negative selection	5825443
9762132	9762155	19	-	27260156	A375	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.06775477440604938	[1149]	[1404,1650,1422,1204]	1	hSpCas9	negative selection	5825444
9764935	9764958	19	-	27260156	A375	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.28199097741668677	[774]	[876,836,808,495]	-4	hSpCas9	negative selection	5889689
9762082	9762105	19	-	27260156	A375	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.08181295538181999	[308]	[473,382,461,226]	1	hSpCas9	negative selection	5889690
9759888	9759911	19	+	27260156	A375	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.05263061382673717	[362]	[473,518,552,245]	0	hSpCas9	negative selection	5889691
9759855	9759878	19	+	27260156	COLO741	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.45340962694833364	[1149]	[2359,1546,2142]	8	hSpCas9	negative selection	5946693
9763318	9763341	19	+	27260156	COLO741	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.26429511550142204	[216]	[353,298,345]	5	hSpCas9	negative selection	5946694
9762132	9762155	19	-	27260156	COLO741	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.23906586150643183	[1149]	[1541,1126,1098]	-5	hSpCas9	negative selection	5946695
9764935	9764958	19	-	27260156	COLO741	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.07070266641249101	[774]	[1160,1099,878]	1	hSpCas9	negative selection	6010940
9762082	9762105	19	-	27260156	COLO741	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.05828588549112923	[308]	[364,425,346]	-1	hSpCas9	negative selection	6010941
9759888	9759911	19	+	27260156	COLO741	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.14332921212315183	[362]	[681,429,442]	3	hSpCas9	negative selection	6010942
9759855	9759878	19	+	27260156	CAL120	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.5663779221412026	[1149]	[2139,2069,2148]	8	hSpCas9	negative selection	6067944
9763318	9763341	19	+	27260156	CAL120	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.889791286761259	[216]	[637,464,419]	9	hSpCas9	negative selection	6067945
9762132	9762155	19	-	27260156	CAL120	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.211844030050373	[1149]	[1361,1052,1308]	-3	hSpCas9	negative selection	6067946
9764935	9764958	19	-	27260156	CAL120	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.12103599476492155	[774]	[1180,1055,930]	1	hSpCas9	negative selection	6132191
9762082	9762105	19	-	27260156	CAL120	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.5872156473068404	[308]	[713,500,538]	8	hSpCas9	negative selection	6132192
9759888	9759911	19	+	27260156	CAL120	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.4713205377966193	[362]	[514,902,446]	7	hSpCas9	negative selection	6132193
9759855	9759878	19	+	27260156	CADOES1	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.5817877358439354	[1149]	[1707,1418,1486,1795]	8	hSpCas9	negative selection	6189195
9763318	9763341	19	+	27260156	CADOES1	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.7363916693674444	[216]	[388,316,296,341]	9	hSpCas9	negative selection	6189196
9762132	9762155	19	-	27260156	CADOES1	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.02705998461865433	[1149]	[1156,1126,964,1110]	0	hSpCas9	negative selection	6189197
9764935	9764958	19	-	27260156	CADOES1	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.017134719767328388	[774]	[607,708,905,622]	0	hSpCas9	negative selection	6253442
9762082	9762105	19	-	27260156	CADOES1	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.054505948923362135	[308]	[267,255,263,409]	0	hSpCas9	negative selection	6253443
9759888	9759911	19	+	27260156	CADOES1	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.06237434555727467	[362]	[307,333,419,347]	1	hSpCas9	negative selection	6253444
9759855	9759878	19	+	27260156	EWS502	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.48761854016148054	[1149]	[1659,1853,1684,1618]	8	hSpCas9	negative selection	6310446
9763318	9763341	19	+	27260156	EWS502	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.6114596344177111	[216]	[381,305,273,444]	9	hSpCas9	negative selection	6310447
9762132	9762155	19	-	27260156	EWS502	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.09374177945283257	[1149]	[1218,1054,984,1305]	-2	hSpCas9	negative selection	6310448
9764935	9764958	19	-	27260156	EWS502	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.058567714625501255	[774]	[789,587,858,931]	-1	hSpCas9	negative selection	6374693
9762082	9762105	19	-	27260156	EWS502	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.08338639415622251	[308]	[304,412,414,248]	1	hSpCas9	negative selection	6374694
9759888	9759911	19	+	27260156	EWS502	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.36147763502137825	[362]	[654,497,345,449]	6	hSpCas9	negative selection	6374695
9759855	9759878	19	+	27260156	EW8	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.45055699397636984	[1149]	[1468,1202,1166,1290]	7	hSpCas9	negative selection	6431697
9763318	9763341	19	+	27260156	EW8	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.5453488477390862	[216]	[256,323,240,206]	8	hSpCas9	negative selection	6431698
9762132	9762155	19	-	27260156	EW8	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.034016240729384695	[1149]	[1174,912,623,1003]	0	hSpCas9	negative selection	6431699
9764935	9764958	19	-	27260156	EW8	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.18362297716846288	[774]	[721,639,722,764]	3	hSpCas9	negative selection	6495944
9762082	9762105	19	-	27260156	EW8	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.14306632137287228	[308]	[270,286,286,257]	2	hSpCas9	negative selection	6495945
9759888	9759911	19	+	27260156	EW8	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.2342558704528334	[362]	[319,401,313,349]	4	hSpCas9	negative selection	6495946
9759855	9759878	19	+	27260156	CORL105	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.27924261553839913	[1149]	[1691,1608,1719,1529]	5	hSpCas9	negative selection	6552948
9763318	9763341	19	+	27260156	CORL105	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.36093638812111095	[216]	[415,347,294,243]	6	hSpCas9	negative selection	6552949
9762132	9762155	19	-	27260156	CORL105	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.1749059387056333	[1149]	[1335,967,1305,1186]	-3	hSpCas9	negative selection	6552950
9764935	9764958	19	-	27260156	CORL105	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.14304242417464108	[774]	[927,921,1367,845]	2	hSpCas9	negative selection	6617195
9762082	9762105	19	-	27260156	CORL105	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.021090783615666853	[308]	[260,302,522,402]	0	hSpCas9	negative selection	6617196
9759888	9759911	19	+	27260156	CORL105	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	-0.05403250890529199	[362]	[468,341,455,380]	-1	hSpCas9	negative selection	6617197
9759855	9759878	19	+	27260156	HS294T	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.6247868527101672	[1149]	[673,833,568,653]	7	hSpCas9	negative selection	6674199
9763318	9763341	19	+	27260156	HS294T	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.36710854469603205	[216]	[95,131,95,108]	5	hSpCas9	negative selection	6674200
9762132	9762155	19	-	27260156	HS294T	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.22730565919483192	[1149]	[510,530,492,550]	3	hSpCas9	negative selection	6674201
9764935	9764958	19	-	27260156	HS294T	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.023793520410435032	[774]	[176,416,252,346]	0	hSpCas9	negative selection	6738446
9762082	9762105	19	-	27260156	HS294T	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.6935511950504945	[308]	[93,48,82,66]	-7	hSpCas9	negative selection	6738447
9759888	9759911	19	+	27260156	HS294T	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.5211593254537623	[362]	[149,267,146,250]	7	hSpCas9	negative selection	6738448
9759855	9759878	19	+	27260156	HCC44	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.4800126060701875	[1149]	[1896,1408,2457,1658]	7	hSpCas9	negative selection	6795450
9763318	9763341	19	+	27260156	HCC44	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.2781008908952184	[216]	[310,229,408,268]	4	hSpCas9	negative selection	6795451
9762132	9762155	19	-	27260156	HCC44	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.3796427798477202	[1149]	[1568,1609,1782,1804]	6	hSpCas9	negative selection	6795452
9764935	9764958	19	-	27260156	HCC44	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.15592860226936844	[774]	[1189,689,1304,834]	2	hSpCas9	negative selection	6859697
9762082	9762105	19	-	27260156	HCC44	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.04286630910995792	[308]	[413,316,340,293]	0	hSpCas9	negative selection	6859698
9759888	9759911	19	+	27260156	HCC44	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.39246551515348455	[362]	[514,479,620,554]	6	hSpCas9	negative selection	6859699
9759855	9759878	19	+	27260156	G402	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.7943111804662573	[1149]	[2981,2466,1967,2390]	8	hSpCas9	negative selection	6916701
9763318	9763341	19	+	27260156	G402	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.6073293607266773	[216]	[262,560,291,480]	7	hSpCas9	negative selection	6916702
9762132	9762155	19	-	27260156	G402	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.2119448142671414	[1149]	[1641,1465,1669,1705]	2	hSpCas9	negative selection	6916703
9764935	9764958	19	-	27260156	G402	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.1223715935721349	[774]	[1061,947,1339,775]	1	hSpCas9	negative selection	6980948
9762082	9762105	19	-	27260156	G402	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.14672782886749403	[308]	[474,247,331,320]	-2	hSpCas9	negative selection	6980949
9759888	9759911	19	+	27260156	G402	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.373674149064968	[362]	[742,636,464,480]	5	hSpCas9	negative selection	6980950
9759855	9759878	19	+	27260156	L33	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.31147980471121395	[1149]	[1482,576,903,1377]	6	hSpCas9	negative selection	7037952
9763318	9763341	19	+	27260156	L33	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.31712982178102833	[216]	[290,127,163,216]	6	hSpCas9	negative selection	7037953
9762132	9762155	19	-	27260156	L33	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.2484750861363021	[1149]	[1300,611,848,1320]	5	hSpCas9	negative selection	7037954
9764935	9764958	19	-	27260156	L33	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.31556103217351417	[774]	[672,273,423,474]	-6	hSpCas9	negative selection	7102199
9762082	9762105	19	-	27260156	L33	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.4205176965122175	[308]	[198,136,142,163]	-7	hSpCas9	negative selection	7102200
9759888	9759911	19	+	27260156	L33	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.3594848348631988	[362]	[542,188,280,409]	7	hSpCas9	negative selection	7102201
9759855	9759878	19	+	27260156	K562	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.44306009353683895	[1149]	[1482,1209,1638,1228]	5	hSpCas9	negative selection	7159203
9763318	9763341	19	+	27260156	K562	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.8849475193591502	[216]	[316,285,472,339]	9	hSpCas9	negative selection	7159204
9762132	9762155	19	-	27260156	K562	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.507943810475332	[1149]	[900,636,571,762]	-6	hSpCas9	negative selection	7159205
9764935	9764958	19	-	27260156	K562	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.060940541332967335	[774]	[726,951,579,630]	0	hSpCas9	negative selection	7223450
9762082	9762105	19	-	27260156	K562	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.19789488195136196	[308]	[237,430,186,122]	-2	hSpCas9	negative selection	7223451
9759888	9759911	19	+	27260156	K562	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.41582808168926333	[362]	[386,677,413,266]	5	hSpCas9	negative selection	7223452
9759855	9759878	19	+	27260156	HT29	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.5434549287463006	[1149]	[2171,2307,1852,1857]	9	hSpCas9	negative selection	7280454
9763318	9763341	19	+	27260156	HT29	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.5332073937993493	[216]	[363,455,298,406]	8	hSpCas9	negative selection	7280455
9762132	9762155	19	-	27260156	HT29	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.03248691066615517	[1149]	[1405,1568,1389,1140]	0	hSpCas9	negative selection	7280456
9764935	9764958	19	-	27260156	HT29	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.19897172297151378	[774]	[1237,1036,1184,889]	4	hSpCas9	negative selection	7344701
9762082	9762105	19	-	27260156	HT29	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.1286596135153366	[308]	[452,556,454,214]	2	hSpCas9	negative selection	7344702
9759888	9759911	19	+	27260156	HT29	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.2197894245393769	[362]	[527,641,470,432]	4	hSpCas9	negative selection	7344703
9759855	9759878	19	+	27260156	MHHES1	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.6054192429467606	[1149]	[2242,1978,2307,1462]	9	hSpCas9	negative selection	7401705
9763318	9763341	19	+	27260156	MHHES1	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.3563529670216753	[216]	[318,308,457,188]	6	hSpCas9	negative selection	7401706
9762132	9762155	19	-	27260156	MHHES1	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.2923952505188001	[1149]	[1607,1454,2429,958]	5	hSpCas9	negative selection	7401707
9764935	9764958	19	-	27260156	MHHES1	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.011431204863531774	[774]	[913,1008,859,760]	0	hSpCas9	negative selection	7465952
9762082	9762105	19	-	27260156	MHHES1	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.5983827306995737	[308]	[249,380,151,163]	-8	hSpCas9	negative selection	7465953
9759888	9759911	19	+	27260156	MHHES1	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.4861470724733316	[362]	[611,565,767,381]	8	hSpCas9	negative selection	7465954
9759855	9759878	19	+	27260156	MEWO	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.329803644393281	[1149]	[1879,1073,1205]	7	hSpCas9	negative selection	7522956
9763318	9763341	19	+	27260156	MEWO	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.6424791719497847	[216]	[247,380,307]	9	hSpCas9	negative selection	7522957
9762132	9762155	19	-	27260156	MEWO	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.08370702510336558	[1149]	[1546,948,1003]	1	hSpCas9	negative selection	7522958
9764935	9764958	19	-	27260156	MEWO	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.10106449409181018	[774]	[931,725,704]	2	hSpCas9	negative selection	7587203
9762082	9762105	19	-	27260156	MEWO	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.26152905507475777	[308]	[238,241,241]	-5	hSpCas9	negative selection	7587204
9759888	9759911	19	+	27260156	MEWO	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.23518788984066913	[362]	[480,373,359]	5	hSpCas9	negative selection	7587205
9759855	9759878	19	+	27260156	LNCAPCLONEFGC	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.5975987738648416	[1149]	[1597,1418,1634,1670]	8	hSpCas9	negative selection	7644207
9763318	9763341	19	+	27260156	LNCAPCLONEFGC	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.2937479700505803	[216]	[218,203,243,299]	4	hSpCas9	negative selection	7644208
9762132	9762155	19	-	27260156	LNCAPCLONEFGC	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.031120669513104104	[1149]	[904,1080,1346,967]	0	hSpCas9	negative selection	7644209
9764935	9764958	19	-	27260156	LNCAPCLONEFGC	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.038008089291328595	[774]	[623,552,693,874]	0	hSpCas9	negative selection	7708454
9762082	9762105	19	-	27260156	LNCAPCLONEFGC	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.09334185694748431	[308]	[207,215,373,271]	-1	hSpCas9	negative selection	7708455
9759888	9759911	19	+	27260156	LNCAPCLONEFGC	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.23137921170948436	[362]	[348,373,450,380]	3	hSpCas9	negative selection	7708456
9759855	9759878	19	+	27260156	PANC0327	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.5190800893909333	[1149]	[1155,1541,1540,1580]	7	hSpCas9	negative selection	7765458
9763318	9763341	19	+	27260156	PANC0327	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.8113336423293334	[216]	[378,238,308,441]	9	hSpCas9	negative selection	7765459
9762132	9762155	19	-	27260156	PANC0327	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.009204271070350822	[1149]	[1508,884,963,811]	0	hSpCas9	negative selection	7765460
9764935	9764958	19	-	27260156	PANC0327	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.1068070214918474	[774]	[1011,416,689,909]	1	hSpCas9	negative selection	7829705
9762082	9762105	19	-	27260156	PANC0327	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.043607685894893944	[308]	[284,164,340,355]	0	hSpCas9	negative selection	7829706
9759888	9759911	19	+	27260156	PANC0327	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.3285983622223022	[362]	[501,325,498,310]	5	hSpCas9	negative selection	7829707
9759855	9759878	19	+	27260156	NCIH2009	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.5073047927843204	[1149]	[2805,1937,2212]	7	hSpCas9	negative selection	7886709
9763318	9763341	19	+	27260156	NCIH2009	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.5459086287444429	[216]	[443,464,417]	7	hSpCas9	negative selection	7886710
9762132	9762155	19	-	27260156	NCIH2009	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.20965629021451448	[1149]	[2214,1721,1706]	3	hSpCas9	negative selection	7886711
9764935	9764958	19	-	27260156	NCIH2009	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.2891885219603504	[774]	[999,795,884]	-4	hSpCas9	negative selection	7950956
9762082	9762105	19	-	27260156	NCIH2009	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.5967406682926157	[308]	[461,220,208]	-6	hSpCas9	negative selection	7950957
9759888	9759911	19	+	27260156	NCIH2009	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.24838522797152504	[362]	[653,410,754]	3	hSpCas9	negative selection	7950958
9759855	9759878	19	+	27260156	NCIH1373	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.8617376589328736	[1149]	[2883,2123,2082,625]	8	hSpCas9	negative selection	8007960
9763318	9763341	19	+	27260156	NCIH1373	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	1.5167777709188355	[216]	[465,677,708,237]	9	hSpCas9	negative selection	8007961
9762132	9762155	19	-	27260156	NCIH1373	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.1069722528368604	[1149]	[1901,1019,1631,285]	1	hSpCas9	negative selection	8007962
9764935	9764958	19	-	27260156	NCIH1373	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.1621056729864636	[774]	[733,579,792,268]	-2	hSpCas9	negative selection	8072207
9762082	9762105	19	-	27260156	NCIH1373	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.4410482077651865	[308]	[491,159,213,51]	-4	hSpCas9	negative selection	8072208
9759888	9759911	19	+	27260156	NCIH1373	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	-0.1397395776745411	[362]	[606,153,229,146]	-1	hSpCas9	negative selection	8072209
9759855	9759878	19	+	27260156	PATU8902	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.0003927096471150193	[1149]	[1518,2185,1183,1619]	0	hSpCas9	negative selection	8129211
9763318	9763341	19	+	27260156	PATU8902	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.4993485478318742	[216]	[382,324,176,947]	5	hSpCas9	negative selection	8129212
9762132	9762155	19	-	27260156	PATU8902	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.12260272155141982	[1149]	[1340,1307,1524,1714]	-1	hSpCas9	negative selection	8129213
9764935	9764958	19	-	27260156	PATU8902	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.40549620873984654	[774]	[1219,567,305,1348]	-4	hSpCas9	negative selection	8193458
9762082	9762105	19	-	27260156	PATU8902	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.13519959092109712	[308]	[233,240,536,532]	-1	hSpCas9	negative selection	8193459
9759888	9759911	19	+	27260156	PATU8902	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	-0.3991151464687	[362]	[416,312,304,532]	-4	hSpCas9	negative selection	8193460
9759855	9759878	19	+	27260156	PANC1	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.4143189678315138	[1149]	[1160,1863,1222,1139]	6	hSpCas9	negative selection	8250462
9763318	9763341	19	+	27260156	PANC1	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.5958888300723966	[216]	[275,253,326,262]	8	hSpCas9	negative selection	8250463
9762132	9762155	19	-	27260156	PANC1	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.15759009475685581	[1149]	[751,1162,981,718]	-3	hSpCas9	negative selection	8250464
9764935	9764958	19	-	27260156	PANC1	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.38718769829831634	[774]	[678,1152,988,732]	6	hSpCas9	negative selection	8314709
9762082	9762105	19	-	27260156	PANC1	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.15437416899213313	[308]	[168,526,238,291]	2	hSpCas9	negative selection	8314710
9759888	9759911	19	+	27260156	PANC1	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.1972789748258758	[362]	[250,392,563,245]	3	hSpCas9	negative selection	8314711
9759855	9759878	19	+	27260156	PANC0813	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.2949360349578223	[1149]	[2327,1603,1343,1423]	5	hSpCas9	negative selection	8371713
9763318	9763341	19	+	27260156	PANC0813	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.4300529197834311	[216]	[351,384,230,401]	7	hSpCas9	negative selection	8371714
9762132	9762155	19	-	27260156	PANC0813	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.08475890808061903	[1149]	[1841,1611,1322,1011]	1	hSpCas9	negative selection	8371715
9764935	9764958	19	-	27260156	PANC0813	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.10347064974880338	[774]	[916,724,1063,697]	-2	hSpCas9	negative selection	8435960
9762082	9762105	19	-	27260156	PANC0813	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.06219588295338063	[308]	[342,362,493,315]	1	hSpCas9	negative selection	8435961
9759888	9759911	19	+	27260156	PANC0813	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.4389219903964289	[362]	[505,647,462,680]	7	hSpCas9	negative selection	8435962
9759855	9759878	19	+	27260156	RDES	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.5655228647713564	[1149]	[1564,1712,2137,2562]	8	hSpCas9	negative selection	8492964
9763318	9763341	19	+	27260156	RDES	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.6946029578851837	[216]	[339,478,444,335]	9	hSpCas9	negative selection	8492965
9762132	9762155	19	-	27260156	RDES	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.02179477254838469	[1149]	[923,1493,1281,1576]	0	hSpCas9	negative selection	8492966
9764935	9764958	19	-	27260156	RDES	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.1213034296463611	[774]	[910,711,1121,1176]	2	hSpCas9	negative selection	8557211
9762082	9762105	19	-	27260156	RDES	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.10473266020466387	[308]	[341,419,357,402]	1	hSpCas9	negative selection	8557212
9759888	9759911	19	+	27260156	RDES	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.2652678186708682	[362]	[493,525,408,565]	4	hSpCas9	negative selection	8557213
9759855	9759878	19	+	27260156	PC3	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.28357714627056607	[1149]	[806,1510,2214,1494]	6	hSpCas9	negative selection	8614215
9763318	9763341	19	+	27260156	PC3	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.4307767110616396	[216]	[263,215,517,230]	8	hSpCas9	negative selection	8614216
9762132	9762155	19	-	27260156	PC3	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.034983566407501554	[1149]	[639,1433,1671,1028]	-1	hSpCas9	negative selection	8614217
9764935	9764958	19	-	27260156	PC3	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.21770889168637297	[774]	[549,875,1658,871]	5	hSpCas9	negative selection	8678462
9762082	9762105	19	-	27260156	PC3	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.11152485619777386	[308]	[148,384,272,360]	-3	hSpCas9	negative selection	8678463
9759888	9759911	19	+	27260156	PC3	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.4928241133615819	[362]	[445,388,899,417]	8	hSpCas9	negative selection	8678464
9759855	9759878	19	+	27260156	PATU8988T	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.5871390613030907	[1149]	[1495,1779,1697,1716]	8	hSpCas9	negative selection	8735466
9763318	9763341	19	+	27260156	PATU8988T	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.9335945436025902	[216]	[566,197,248,585]	9	hSpCas9	negative selection	8735467
9762132	9762155	19	-	27260156	PATU8988T	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.24517292326018225	[1149]	[1275,891,1526,1548]	4	hSpCas9	negative selection	8735468
9764935	9764958	19	-	27260156	PATU8988T	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.09360101060248416	[774]	[622,924,665,606]	-2	hSpCas9	negative selection	8799713
9762082	9762105	19	-	27260156	PATU8988T	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.3202067637097853	[308]	[235,201,290,221]	-5	hSpCas9	negative selection	8799714
9759888	9759911	19	+	27260156	PATU8988T	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.3821881653812341	[362]	[661,454,277,433]	6	hSpCas9	negative selection	8799715
9759855	9759878	19	+	27260156	T47D	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.4454046643351668	[1149]	[1987,1564,1860,1907]	8	hSpCas9	negative selection	8856717
9763318	9763341	19	+	27260156	T47D	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.32137147591159	[216]	[356,326,373,199]	6	hSpCas9	negative selection	8856718
9762132	9762155	19	-	27260156	T47D	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.05623390438700371	[1149]	[1172,1162,1376,1454]	-1	hSpCas9	negative selection	8856719
9764935	9764958	19	-	27260156	T47D	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.16906722341117586	[774]	[1098,919,921,1132]	3	hSpCas9	negative selection	8920964
9762082	9762105	19	-	27260156	T47D	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.1990063550036757	[308]	[308,326,328,286]	-4	hSpCas9	negative selection	8920965
9759888	9759911	19	+	27260156	T47D	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.33021448117695	[362]	[650,412,523,549]	7	hSpCas9	negative selection	8920966
9759855	9759878	19	+	27260156	SU8686	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.5824341836387652	[1149]	[1421,1369,2017,2165]	8	hSpCas9	negative selection	8977968
9763318	9763341	19	+	27260156	SU8686	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.4725710540268808	[216]	[253,269,317,370]	7	hSpCas9	negative selection	8977969
9762132	9762155	19	-	27260156	SU8686	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.26844577651512913	[1149]	[1099,1270,1448,1774]	4	hSpCas9	negative selection	8977970
9764935	9764958	19	-	27260156	SU8686	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.2039379579176016	[774]	[527,723,600,845]	-4	hSpCas9	negative selection	9042215
9762082	9762105	19	-	27260156	SU8686	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.11139403499473988	[308]	[252,265,395,214]	-2	hSpCas9	negative selection	9042216
9759888	9759911	19	+	27260156	SU8686	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.3839370483324123	[362]	[423,444,543,472]	6	hSpCas9	negative selection	9042217
9759855	9759878	19	+	27260156	SKES1	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.4808411547054283	[1149]	[1599,1922,1489,1433]	8	hSpCas9	negative selection	9099219
9763318	9763341	19	+	27260156	SKES1	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.45962185312627113	[216]	[524,252,245,201]	8	hSpCas9	negative selection	9099220
9762132	9762155	19	-	27260156	SKES1	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.18117598665297874	[1149]	[1156,1080,958,883]	-4	hSpCas9	negative selection	9099221
9764935	9764958	19	-	27260156	SKES1	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.12372351035234408	[774]	[824,767,700,575]	-3	hSpCas9	negative selection	9163466
9762082	9762105	19	-	27260156	SKES1	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.17382795051270872	[308]	[343,308,215,239]	-4	hSpCas9	negative selection	9163467
9759888	9759911	19	+	27260156	SKES1	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.2772732197725061	[362]	[452,372,404,505]	6	hSpCas9	negative selection	9163468
9759855	9759878	19	+	27260156	TOV112D	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.4881908844057514	[1149]	[1618,1744,1337,1784]	8	hSpCas9	negative selection	9220470
9763318	9763341	19	+	27260156	TOV112D	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.09325997926746821	[216]	[207,359,136,250]	1	hSpCas9	negative selection	9220471
9762132	9762155	19	-	27260156	TOV112D	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.13863381556869347	[1149]	[1088,1571,852,808]	-3	hSpCas9	negative selection	9220472
9764935	9764958	19	-	27260156	TOV112D	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	-0.011615165765661795	[774]	[898,701,818,655]	0	hSpCas9	negative selection	9284717
9762082	9762105	19	-	27260156	TOV112D	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.2550891756781764	[308]	[422,373,482,206]	5	hSpCas9	negative selection	9284718
9759888	9759911	19	+	27260156	TOV112D	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.2654296545607445	[362]	[607,410,252,481]	5	hSpCas9	negative selection	9284719
9759855	9759878	19	+	27260156	TC71	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.4326953318869864	[1149]	[1651,1585,1549,1884]	8	hSpCas9	negative selection	9341721
9763318	9763341	19	+	27260156	TC71	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.34286979825830766	[216]	[271,328,233,350]	7	hSpCas9	negative selection	9341722
9762132	9762155	19	-	27260156	TC71	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	-0.16183487710769784	[1149]	[965,1047,1054,1358]	-4	hSpCas9	negative selection	9341723
9764935	9764958	19	-	27260156	TC71	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.1509920846049777	[774]	[971,965,775,982]	4	hSpCas9	negative selection	9405968
9762082	9762105	19	-	27260156	TC71	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	0.022312761294350114	[308]	[242,309,431,360]	0	hSpCas9	negative selection	9405969
9759888	9759911	19	+	27260156	TC71	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.3008432873257001	[362]	[539,417,527,424]	7	hSpCas9	negative selection	9405970
9759855	9759878	19	+	27260156	TC32	viability	CTTACCAATTGTACTCCATTTGG	ZNF846	ENSG00000196605	0.5073416799627315	[1149]	[1305,1248,2004,1721]	8	hSpCas9	negative selection	9462972
9763318	9763341	19	+	27260156	TC32	viability	CATCTCTGTAGAGATCTCTCTGG	ZNF846	ENSG00000196605	0.2505393569545852	[216]	[250,152,281,313]	4	hSpCas9	negative selection	9462973
9762132	9762155	19	-	27260156	TC32	viability	TTCAAACGTAGTCTCATGTCTGG	ZNF846	ENSG00000196605	0.10972199659958659	[1149]	[1250,908,1309,1236]	2	hSpCas9	negative selection	9462974
9764935	9764958	19	-	27260156	TC32	viability	ATTACTGATGGATTCTTCTCAGG	ZNF846	ENSG00000196605	0.1295919867667168	[774]	[703,647,1042,857]	2	hSpCas9	negative selection	9527219
9762082	9762105	19	-	27260156	TC32	viability	AGGAGTGACAGGAGTTCTGCAGG	ZNF846	ENSG00000196605	-0.04566904687599693	[308]	[231,230,335,347]	-1	hSpCas9	negative selection	9527220
9759888	9759911	19	+	27260156	TC32	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.33106808233673873	[362]	[355,304,574,543]	6	hSpCas9	negative selection	9527221
9757754	9757777	19	+	27869803	HPAFII	viability after 27 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	0.14460969094505835	[195]	[144,87,NaN]	1	hSpCas9	negative selection	9570928
9758343	9758366	19	-	27869803	HPAFII	viability after 27 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.33170572735476433	[186]	[222,40,NaN]	2	hSpCas9	negative selection	9570929
9757754	9757777	19	+	27869803	HPAFII	viability after 15 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	-0.39914763717819435	[195]	[176,148,NaN]	-4	hSpCas9	negative selection	9653377
9758343	9758366	19	-	27869803	HPAFII	viability after 15 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.46376573240720737	[186]	[500,137,NaN]	5	hSpCas9	negative selection	9653378
9757754	9757777	19	+	27869803	ASPC1	viability after 36 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	-0.4200554362306914	[405]	[88,199,41]	-4	hSpCas9	negative selection	9735826
9758343	9758366	19	-	27869803	ASPC1	viability after 36 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	-0.1796641682659488	[628]	[355,135,123]	-2	hSpCas9	negative selection	9735827
9757754	9757777	19	+	27869803	PATU8988S	viability after 35 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	0.15665069566110912	[369]	[213,117,NaN]	1	hSpCas9	negative selection	9818275
9758343	9758366	19	-	27869803	PATU8988S	viability after 35 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.8070882577883398	[432]	[360,248,NaN]	8	hSpCas9	negative selection	9818276
9757754	9757777	19	+	27869803	PATU8988S	viability after 31 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	-0.26700837865446736	[369]	[159,74,NaN]	-3	hSpCas9	negative selection	9900724
9758343	9758366	19	-	27869803	PATU8988S	viability after 31 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.9871196423251325	[432]	[354,325,NaN]	9	hSpCas9	negative selection	9900725
9757754	9757777	19	+	27869803	HPAFII	viability after 35 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	-0.40494352202722195	[195]	[73,75,NaN]	-2	hSpCas9	negative selection	9983173
9758343	9758366	19	-	27869803	HPAFII	viability after 35 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.7744807907823916	[186]	[271,37,NaN]	5	hSpCas9	negative selection	9983174
9757754	9757777	19	+	27869803	HPAFII	viability after 31 days	TAAATGGGTACTAAGGCCCGAGG	ZNF846	ENSG00000196605	-0.18525540348927527	[195]	[90,102,NaN]	-1	hSpCas9	negative selection	10065622
9758343	9758366	19	-	27869803	HPAFII	viability after 31 days	TCCTCACACCTTATAGGACATGG	ZNF846	ENSG00000196605	0.7198535331626571	[186]	[269,66,NaN]	5	hSpCas9	negative selection	10065623
9759888	9759911	19	+	28162770	P31FUJ	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.41157378181377635	[443]	[693]	4	hSpCas9	negative selection	10273213
9758244	9758267	19	-	28162770	P31FUJ	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	0.3746305771104722	[360]	[549]	4	hSpCas9	negative selection	10273214
9762081	9762104	19	-	28162770	P31FUJ	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	1.0832252890332996	[195]	[487]	9	hSpCas9	negative selection	10273215
9762102	9762125	19	-	28162770	P31FUJ	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.20221388458095557	[139]	[142]	-2	hSpCas9	negative selection	10273216
9759870	9759893	19	-	28162770	P31FUJ	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.5768157691517943	[363]	[637]	6	hSpCas9	negative selection	10273217
9762127	9762150	19	-	28162770	P31FUJ	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	0.446830214685876	[230]	[369]	5	hSpCas9	negative selection	10273218
9758328	9758351	19	-	28162770	P31FUJ	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-0.20261017493941202	[330]	[337]	-2	hSpCas9	negative selection	10273219
9758160	9758183	19	-	28162770	P31FUJ	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	0.6223812427338405	[177]	[321]	7	hSpCas9	negative selection	10273220
9758354	9758377	19	+	28162770	P31FUJ	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.9445761168747067	[664]	[1503]	9	hSpCas9	negative selection	10273221
9758274	9758297	19	-	28162770	P31FUJ	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	0.10273294382501119	[400]	[505]	1	hSpCas9	negative selection	10273222
9759888	9759911	19	+	28162770	TF1	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	NaN	[NaN]	[756]	1	hSpCas9	negative selection	10442579
9758244	9758267	19	-	28162770	TF1	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	NaN	[NaN]	[553]	1	hSpCas9	negative selection	10442580
9762081	9762104	19	-	28162770	TF1	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	NaN	[NaN]	[312]	1	hSpCas9	negative selection	10442581
9762102	9762125	19	-	28162770	TF1	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	NaN	[NaN]	[152]	1	hSpCas9	negative selection	10442582
9759870	9759893	19	-	28162770	TF1	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	NaN	[NaN]	[434]	1	hSpCas9	negative selection	10442583
9762127	9762150	19	-	28162770	TF1	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	NaN	[NaN]	[325]	1	hSpCas9	negative selection	10442584
9758328	9758351	19	-	28162770	TF1	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10442585
9758160	9758183	19	-	28162770	TF1	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10442586
9758354	9758377	19	+	28162770	TF1	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	NaN	[NaN]	[448]	1	hSpCas9	negative selection	10442587
9758274	9758297	19	-	28162770	TF1	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	NaN	[NaN]	[408]	1	hSpCas9	negative selection	10442588
9759888	9759911	19	+	28162770	SKM1	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.20019404809219088	[128]	[261]	2	hSpCas9	negative selection	10611945
9758244	9758267	19	-	28162770	SKM1	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	0.3632131744449019	[72]	[165]	3	hSpCas9	negative selection	10611946
9762081	9762104	19	-	28162770	SKM1	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	-0.09118833083739464	[93]	[155]	-1	hSpCas9	negative selection	10611947
9762102	9762125	19	-	28162770	SKM1	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.583841960827241	[38]	[45]	-4	hSpCas9	negative selection	10611948
9759870	9759893	19	-	28162770	SKM1	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.9831353987857799	[92]	[324]	8	hSpCas9	negative selection	10611949
9762127	9762150	19	-	28162770	SKM1	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	1.1419290472704728	[80]	[315]	9	hSpCas9	negative selection	10611950
9758328	9758351	19	-	28162770	SKM1	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	0.16906517720798686	[80]	[160]	1	hSpCas9	negative selection	10611951
9758160	9758183	19	-	28162770	SKM1	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	-0.014646775964401407	[51]	[90]	0	hSpCas9	negative selection	10611952
9758354	9758377	19	+	28162770	SKM1	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.916145948681355	[121]	[406]	8	hSpCas9	negative selection	10611953
9758274	9758297	19	-	28162770	SKM1	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	0.3308497900613655	[84]	[188]	3	hSpCas9	negative selection	10611954
9759888	9759911	19	+	28162770	SKM1	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.20019404809219088	[128]	[261]	2	hSpCas9	negative selection	10781311
9758244	9758267	19	-	28162770	SKM1	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	0.3632131744449019	[72]	[165]	3	hSpCas9	negative selection	10781312
9762081	9762104	19	-	28162770	SKM1	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	-0.09118833083739464	[93]	[155]	-1	hSpCas9	negative selection	10781313
9762102	9762125	19	-	28162770	SKM1	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.583841960827241	[38]	[45]	-4	hSpCas9	negative selection	10781314
9759870	9759893	19	-	28162770	SKM1	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.9831353987857799	[92]	[324]	8	hSpCas9	negative selection	10781315
9762127	9762150	19	-	28162770	SKM1	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	1.1419290472704728	[80]	[315]	9	hSpCas9	negative selection	10781316
9758328	9758351	19	-	28162770	SKM1	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	0.16906517720798686	[80]	[160]	1	hSpCas9	negative selection	10781317
9758160	9758183	19	-	28162770	SKM1	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	-0.014646775964401407	[51]	[90]	0	hSpCas9	negative selection	10781318
9758354	9758377	19	+	28162770	SKM1	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.916145948681355	[121]	[406]	8	hSpCas9	negative selection	10781319
9758274	9758297	19	-	28162770	SKM1	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	0.3308497900613655	[84]	[188]	3	hSpCas9	negative selection	10781320
9759888	9759911	19	+	28162770	PL21	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	1.0422147270310327	[433]	[388]	8	hSpCas9	negative selection	10950677
9758244	9758267	19	-	28162770	PL21	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	0.30630517170624794	[274]	[147]	2	hSpCas9	negative selection	10950678
9762081	9762104	19	-	28162770	PL21	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	0.0945294265287212	[339]	[157]	0	hSpCas9	negative selection	10950679
9762102	9762125	19	-	28162770	PL21	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	0.7688003028813759	[177]	[131]	6	hSpCas9	negative selection	10950680
9759870	9759893	19	-	28162770	PL21	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.6065381954942914	[334]	[221]	5	hSpCas9	negative selection	10950681
9762127	9762150	19	-	28162770	PL21	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	0.5535380479757781	[262]	[167]	5	hSpCas9	negative selection	10950682
9758328	9758351	19	-	28162770	PL21	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-0.07908402944380405	[232]	[95]	0	hSpCas9	negative selection	10950683
9758160	9758183	19	-	28162770	PL21	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	0.23019684834549992	[189]	[96]	2	hSpCas9	negative selection	10950684
9758354	9758377	19	+	28162770	PL21	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.6340741451826706	[492]	[332]	5	hSpCas9	negative selection	10950685
9758274	9758297	19	-	28162770	PL21	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	0.3085157755341119	[281]	[151]	2	hSpCas9	negative selection	10950686
9759888	9759911	19	+	28162770	P31FUJ	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.41157378181377635	[443]	[693]	4	hSpCas9	negative selection	11120043
9758244	9758267	19	-	28162770	P31FUJ	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	0.3746305771104722	[360]	[549]	4	hSpCas9	negative selection	11120044
9762081	9762104	19	-	28162770	P31FUJ	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	1.0832252890332996	[195]	[487]	9	hSpCas9	negative selection	11120045
9762102	9762125	19	-	28162770	P31FUJ	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.20221388458095557	[139]	[142]	-2	hSpCas9	negative selection	11120046
9759870	9759893	19	-	28162770	P31FUJ	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.5768157691517943	[363]	[637]	6	hSpCas9	negative selection	11120047
9762127	9762150	19	-	28162770	P31FUJ	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	0.446830214685876	[230]	[369]	5	hSpCas9	negative selection	11120048
9758328	9758351	19	-	28162770	P31FUJ	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-0.20261017493941202	[330]	[337]	-2	hSpCas9	negative selection	11120049
9758160	9758183	19	-	28162770	P31FUJ	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	0.6223812427338405	[177]	[321]	7	hSpCas9	negative selection	11120050
9758354	9758377	19	+	28162770	P31FUJ	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.9445761168747067	[664]	[1503]	9	hSpCas9	negative selection	11120051
9758274	9758297	19	-	28162770	P31FUJ	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	0.10273294382501119	[400]	[505]	1	hSpCas9	negative selection	11120052
9759888	9759911	19	+	28162770	OCIAML5	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.6002581612790403	[295]	[809]	5	hSpCas9	negative selection	11289409
9758244	9758267	19	-	28162770	OCIAML5	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	-0.7858996468982506	[276]	[289]	-5	hSpCas9	negative selection	11289410
9762081	9762104	19	-	28162770	OCIAML5	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	1.1776807725300549	[143]	[587]	8	hSpCas9	negative selection	11289411
9762102	9762125	19	-	28162770	OCIAML5	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	0.26474709411875297	[82]	[179]	2	hSpCas9	negative selection	11289412
9759870	9759893	19	-	28162770	OCIAML5	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.28871208491879885	[199]	[440]	2	hSpCas9	negative selection	11289413
9762127	9762150	19	-	28162770	OCIAML5	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	0.38433270846633016	[204]	[482]	3	hSpCas9	negative selection	11289414
9758328	9758351	19	-	28162770	OCIAML5	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-2.096303381243665	[243]	[102]	-8	hSpCas9	negative selection	11289415
9758160	9758183	19	-	28162770	OCIAML5	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	-0.11917064100683769	[141]	[235]	-1	hSpCas9	negative selection	11289416
9758354	9758377	19	+	28162770	OCIAML5	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.642828110978104	[357]	[1008]	5	hSpCas9	negative selection	11289417
9758274	9758297	19	-	28162770	OCIAML5	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	0.2252091426126408	[208]	[440]	1	hSpCas9	negative selection	11289418
9759888	9759911	19	+	28162770	EOL1	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.31368340740662126	[842]	[551]	3	hSpCas9	negative selection	11458775
9758244	9758267	19	-	28162770	EOL1	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	-0.9296013619660107	[375]	[103]	-6	hSpCas9	negative selection	11458776
9762081	9762104	19	-	28162770	EOL1	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	-0.5821476723533585	[573]	[201]	-4	hSpCas9	negative selection	11458777
9762102	9762125	19	-	28162770	EOL1	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	0.0016239945891755037	[327]	[172]	0	hSpCas9	negative selection	11458778
9759870	9759893	19	-	28162770	EOL1	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.848967413407281	[528]	[501]	7	hSpCas9	negative selection	11458779
9762127	9762150	19	-	28162770	EOL1	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	0.053152422976083136	[546]	[298]	0	hSpCas9	negative selection	11458780
9758328	9758351	19	-	28162770	EOL1	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-0.7580632931572706	[381]	[118]	-5	hSpCas9	negative selection	11458781
9758160	9758183	19	-	28162770	EOL1	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	0.3595952315808728	[178]	[120]	3	hSpCas9	negative selection	11458782
9758354	9758377	19	+	28162770	EOL1	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.23567646560537348	[589]	[365]	2	hSpCas9	negative selection	11458783
9758274	9758297	19	-	28162770	EOL1	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	-0.4624753515387128	[373]	[142]	-3	hSpCas9	negative selection	11458784
9759888	9759911	19	+	28162770	MOLM13	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	1.5964116839763287	[541]	[1184]	9	hSpCas9	negative selection	11628141
9758244	9758267	19	-	28162770	MOLM13	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	-0.7083943471034895	[738]	[326]	-4	hSpCas9	negative selection	11628142
9762081	9762104	19	-	28162770	MOLM13	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	1.134465647819387	[503]	[799]	8	hSpCas9	negative selection	11628143
9762102	9762125	19	-	28162770	MOLM13	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	0.5258367307538585	[243]	[253]	4	hSpCas9	negative selection	11628144
9759870	9759893	19	-	28162770	MOLM13	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.650806202525094	[650]	[738]	5	hSpCas9	negative selection	11628145
9762127	9762150	19	-	28162770	MOLM13	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	1.6254306585310587	[324]	[724]	9	hSpCas9	negative selection	11628146
9758328	9758351	19	-	28162770	MOLM13	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-1.675068572297464	[476]	[107]	-7	hSpCas9	negative selection	11628147
9758160	9758183	19	-	28162770	MOLM13	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	-0.789164047238486	[336]	[140]	-4	hSpCas9	negative selection	11628148
9758354	9758377	19	+	28162770	MOLM13	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	-0.34970957200982844	[741]	[420]	-2	hSpCas9	negative selection	11628149
9758274	9758297	19	-	28162770	MOLM13	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	-0.6118830371849059	[724]	[342]	-4	hSpCas9	negative selection	11628150
9759888	9759911	19	+	28162770	HEL	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.5221234403306145	[585]	[538]	4	hSpCas9	negative selection	11797507
9758244	9758267	19	-	28162770	HEL	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	0.002634777086739759	[479]	[307]	0	hSpCas9	negative selection	11797508
9762081	9762104	19	-	28162770	HEL	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	1.1524132054172758	[353]	[503]	8	hSpCas9	negative selection	11797509
9762102	9762125	19	-	28162770	HEL	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.6430789694777246	[216]	[88]	-4	hSpCas9	negative selection	11797510
9759870	9759893	19	-	28162770	HEL	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.5090603967683878	[451]	[411]	4	hSpCas9	negative selection	11797511
9762127	9762150	19	-	28162770	HEL	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	0.9341505003646552	[343]	[420]	7	hSpCas9	negative selection	11797512
9758328	9758351	19	-	28162770	HEL	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-2.026287933509274	[317]	[49]	-8	hSpCas9	negative selection	11797513
9758160	9758183	19	-	28162770	HEL	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	-0.7978337593856244	[265]	[97]	-5	hSpCas9	negative selection	11797514
9758354	9758377	19	+	28162770	HEL	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	-0.31950624600422484	[527]	[270]	-2	hSpCas9	negative selection	11797515
9758274	9758297	19	-	28162770	HEL	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	-0.7523239675172209	[525]	[199]	-5	hSpCas9	negative selection	11797516
9759888	9759911	19	+	28162770	MV411	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.1882596148480018	[422]	[405]	1	hSpCas9	negative selection	11966873
9758244	9758267	19	-	28162770	MV411	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	0.4350645539585465	[251]	[286]	4	hSpCas9	negative selection	11966874
9762081	9762104	19	-	28162770	MV411	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	1.4706411585566133	[253]	[592]	9	hSpCas9	negative selection	11966875
9762102	9762125	19	-	28162770	MV411	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.08915859389342247	[172]	[136]	0	hSpCas9	negative selection	11966876
9759870	9759893	19	-	28162770	MV411	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.5777778854863378	[341]	[429]	5	hSpCas9	negative selection	11966877
9762127	9762150	19	-	28162770	MV411	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	0.6034131264978152	[267]	[342]	5	hSpCas9	negative selection	11966878
9758328	9758351	19	-	28162770	MV411	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-2.9335004433819547	[262]	[28]	-9	hSpCas9	negative selection	11966879
9758160	9758183	19	-	28162770	MV411	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	-0.6484540458764863	[146]	[78]	-4	hSpCas9	negative selection	11966880
9758354	9758377	19	+	28162770	MV411	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.32460541130523524	[545]	[575]	3	hSpCas9	negative selection	11966881
9758274	9758297	19	-	28162770	MV411	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	0.8505018578792422	[263]	[400]	7	hSpCas9	negative selection	11966882
9759888	9759911	19	+	28162770	MONOMAC1	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.36288910272427843	[309]	[456]	3	hSpCas9	negative selection	12136239
9758244	9758267	19	-	28162770	MONOMAC1	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	0.1655332323251545	[167]	[215]	1	hSpCas9	negative selection	12136240
9762081	9762104	19	-	28162770	MONOMAC1	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	-0.37674286929445144	[221]	[195]	-3	hSpCas9	negative selection	12136241
9762102	9762125	19	-	28162770	MONOMAC1	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	-0.4633169123970018	[88]	[73]	-4	hSpCas9	negative selection	12136242
9759870	9759893	19	-	28162770	MONOMAC1	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.2533211879522814	[231]	[316]	2	hSpCas9	negative selection	12136243
9762127	9762150	19	-	28162770	MONOMAC1	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	0.5078862777025153	[172]	[281]	5	hSpCas9	negative selection	12136244
9758328	9758351	19	-	28162770	MONOMAC1	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-0.3801591508834428	[150]	[132]	-3	hSpCas9	negative selection	12136245
9758160	9758183	19	-	28162770	MONOMAC1	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	0.2862853917857648	[97]	[136]	3	hSpCas9	negative selection	12136246
9758354	9758377	19	+	28162770	MONOMAC1	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.5285046316584543	[354]	[586]	5	hSpCas9	negative selection	12136247
9758274	9758297	19	-	28162770	MONOMAC1	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	0.15361006494933527	[188]	[240]	1	hSpCas9	negative selection	12136248
9759888	9759911	19	+	28162770	OCIAML2	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.7537429602225274	[77]	[728]	7	hSpCas9	negative selection	12305605
9758244	9758267	19	-	28162770	OCIAML2	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	0.14675415317137236	[43]	[269]	1	hSpCas9	negative selection	12305606
9762081	9762104	19	-	28162770	OCIAML2	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	0.6368986390622836	[62]	[542]	6	hSpCas9	negative selection	12305607
9762102	9762125	19	-	28162770	OCIAML2	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	0.6168330160081781	[31]	[271]	6	hSpCas9	negative selection	12305608
9759870	9759893	19	-	28162770	OCIAML2	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.7846272299999134	[61]	[591]	7	hSpCas9	negative selection	12305609
9762127	9762150	19	-	28162770	OCIAML2	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	0.5451031010224352	[56]	[460]	5	hSpCas9	negative selection	12305610
9758328	9758351	19	-	28162770	OCIAML2	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-1.0706992183535258	[35]	[94]	-6	hSpCas9	negative selection	12305611
9758160	9758183	19	-	28162770	OCIAML2	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	-0.18823009454143627	[36]	[179]	-1	hSpCas9	negative selection	12305612
9758354	9758377	19	+	28162770	OCIAML2	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.8602870528724558	[95]	[965]	8	hSpCas9	negative selection	12305613
9758274	9758297	19	-	28162770	OCIAML2	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	0.019695801340919694	[41]	[235]	0	hSpCas9	negative selection	12305614
9759888	9759911	19	+	28162770	OCIAML3	viability	GCAGAAATATCTTGCAGCAGTGG	ZNF846	ENSG00000196605	0.33805353101926117	[124]	[476]	3	hSpCas9	negative selection	12474971
9758244	9758267	19	-	28162770	OCIAML3	viability	TTACACATCAGAACTCACAGTGG	ZNF846	ENSG00000196605	-0.009045139603006958	[68]	[206]	0	hSpCas9	negative selection	12474972
9762081	9762104	19	-	28162770	OCIAML3	viability	GGAGTGACAGGAGTTCTGCAGGG	ZNF846	ENSG00000196605	0.7454078812920402	[81]	[414]	6	hSpCas9	negative selection	12474973
9762102	9762125	19	-	28162770	OCIAML3	viability	CAAATGGAAGAGCTGAGGACAGG	ZNF846	ENSG00000196605	0.8439137496280191	[42]	[232]	7	hSpCas9	negative selection	12474974
9759870	9759893	19	-	28162770	OCIAML3	viability	TCTGCAGAAAGATCACCAAATGG	ZNF846	ENSG00000196605	0.5507638838898108	[134]	[596]	5	hSpCas9	negative selection	12474975
9762127	9762150	19	-	28162770	OCIAML3	viability	ACGTAGTCTCATGTCTGGATTGG	ZNF846	ENSG00000196605	1.1012611223137707	[85]	[556]	8	hSpCas9	negative selection	12474976
9758328	9758351	19	-	28162770	OCIAML3	viability	GGACATGGAAGAATTCACAGTGG	ZNF846	ENSG00000196605	-1.055141554192461	[52]	[76]	-6	hSpCas9	negative selection	12474977
9758160	9758183	19	-	28162770	OCIAML3	viability	GATCATACAAGAATCCACAGTGG	ZNF846	ENSG00000196605	-0.26143230123729233	[53]	[135]	-2	hSpCas9	negative selection	12474978
9758354	9758377	19	+	28162770	OCIAML3	viability	AAGGTGTGAGGAATTACTGAAGG	ZNF846	ENSG00000196605	0.42822230705930253	[160]	[653]	4	hSpCas9	negative selection	12474979
9758274	9758297	19	-	28162770	OCIAML3	viability	AAAGCTTTCACTCAATCCACAGG	ZNF846	ENSG00000196605	0.3211034620893238	[69]	[263]	3	hSpCas9	negative selection	12474980