| 21210125 | 21210148 | 16 | - | 26472758 | Jiyoye | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | -1.21960729490991 | [209] | [67] | -7 | hSpCas9 | negative selection | 190649 | 21210125 | 21210148 | 16 | - | 26472758 | KBM7 | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | 0.1679431757049013 | [583,321] | [348,129] | 1 | hSpCas9 | negative selection | 381767 | 21210125 | 21210148 | 16 | - | 26472758 | Raji | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | 0.0396389287377652 | [108] | [25] | 0 | hSpCas9 | negative selection | 572885 | 21210125 | 21210148 | 16 | - | 26472758 | K562 | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | 1.18764153596119 | [297] | [572] | 8 | hSpCas9 | negative selection | 764003 | 21206877 | 21206900 | 16 | - | 26627737 | DLD1 | viability | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | 0.5567394852307876 | [326] | [151,264,53] | 5 | hSpCas9 | negative selection | 793069 | 21209701 | 21209724 | 16 | + | 26627737 | DLD1 | viability | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.44187578962627827 | [640] | [340,238,239] | 4 | hSpCas9 | negative selection | 793070 | 21211525 | 21211548 | 16 | - | 26627737 | DLD1 | viability | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -4.580798482116741 | [568] | [20,0,0] | -9 | hSpCas9 | negative selection | 793071 | 21206877 | 21206900 | 16 | - | 26627737 | GBM cells | viability after 5 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | -0.6376157654726109 | [453] | [171,140] | -7 | hSpCas9 | negative selection | 875384 | 21209701 | 21209724 | 16 | + | 26627737 | GBM cells | viability after 5 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.3683991581869057 | [376] | [235,285] | 5 | hSpCas9 | negative selection | 875385 | 21211525 | 21211548 | 16 | - | 26627737 | GBM cells | viability after 5 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -1.044005029907047 | [222] | [61,53] | -9 | hSpCas9 | negative selection | 875386 | 21206877 | 21206900 | 16 | - | 26627737 | GBM cells | viability after 13 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | -0.42030699826631396 | [453] | [193,175] | -5 | hSpCas9 | negative selection | 957699 | 21209701 | 21209724 | 16 | + | 26627737 | GBM cells | viability after 13 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.7046526993319986 | [376] | [382,292] | 8 | hSpCas9 | negative selection | 957700 | 21211525 | 21211548 | 16 | - | 26627737 | GBM cells | viability after 13 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -1.7456340615239694 | [222] | [61,14] | -9 | hSpCas9 | negative selection | 957701 | 21206877 | 21206900 | 16 | - | 26627737 | GBM cells | viability after 21 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | -0.17138174331002987 | [453] | [241,197] | -1 | hSpCas9 | negative selection | 1040014 | 21209701 | 21209724 | 16 | + | 26627737 | GBM cells | viability after 21 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.7275686362090499 | [376] | [370,309] | 7 | hSpCas9 | negative selection | 1040015 | 21211525 | 21211548 | 16 | - | 26627737 | GBM cells | viability after 21 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -1.2372820463432843 | [222] | [53,48] | -7 | hSpCas9 | negative selection | 1040016 | 21206877 | 21206900 | 16 | - | 26627737 | RPE1 | viability after 9 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | -0.34249436813309614 | [962] | [187,301] | -2 | hSpCas9 | negative selection | 1122329 | 21209701 | 21209724 | 16 | + | 26627737 | RPE1 | viability after 9 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.5287166740979203 | [1014] | [419,507] | 3 | hSpCas9 | negative selection | 1122330 | 21211525 | 21211548 | 16 | - | 26627737 | RPE1 | viability after 9 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -6.5437219901473425 | [297] | [0,0] | -9 | hSpCas9 | negative selection | 1122331 | 21206877 | 21206900 | 16 | - | 26627737 | RPE1 | viability after 12 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | 0.1503442878383653 | [962] | [291,281] | 1 | hSpCas9 | negative selection | 1204644 | 21209701 | 21209724 | 16 | + | 26627737 | RPE1 | viability after 12 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.41142350993841253 | [1014] | [368,355] | 2 | hSpCas9 | negative selection | 1204645 | 21211525 | 21211548 | 16 | - | 26627737 | RPE1 | viability after 12 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -4.545449530125472 | [297] | [0,5] | -9 | hSpCas9 | negative selection | 1204646 | 21206877 | 21206900 | 16 | - | 26627737 | RPE1 | viability after 15 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | -0.2096302701778419 | [962] | [315,157] | -1 | hSpCas9 | negative selection | 1286959 | 21209701 | 21209724 | 16 | + | 26627737 | RPE1 | viability after 15 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.6433908145238831 | [1014] | [336,555] | 4 | hSpCas9 | negative selection | 1286960 | 21211525 | 21211548 | 16 | - | 26627737 | RPE1 | viability after 15 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -5.821187550973647 | [297] | [1,0] | -9 | hSpCas9 | negative selection | 1286961 | 21206877 | 21206900 | 16 | - | 26627737 | RPE1 | viability after 18 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | 0.1733597922247151 | [962] | [396,181] | 1 | hSpCas9 | negative selection | 1369274 | 21209701 | 21209724 | 16 | + | 26627737 | RPE1 | viability after 18 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.38367762862490423 | [1014] | [338,376] | 2 | hSpCas9 | negative selection | 1369275 | 21211525 | 21211548 | 16 | - | 26627737 | RPE1 | viability after 18 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -6.329500260361419 | [297] | [0,0] | -9 | hSpCas9 | negative selection | 1369276 | 21206877 | 21206900 | 16 | - | 26627737 | HeLa | viability after 8 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | -0.253603042970011 | [555] | [318,210,110] | -2 | hSpCas9 | negative selection | 1451589 | 21209701 | 21209724 | 16 | + | 26627737 | HeLa | viability after 8 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.717405794172123 | [461] | [487,336,209] | 6 | hSpCas9 | negative selection | 1451590 | 21211525 | 21211548 | 16 | - | 26627737 | HeLa | viability after 8 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -0.028623130042846168 | [486] | [299,186,159] | 0 | hSpCas9 | negative selection | 1451591 | 21206877 | 21206900 | 16 | - | 26627737 | HeLa | viability after 12 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | -0.05670835856646589 | [555] | [242,252,163] | 0 | hSpCas9 | negative selection | 1533904 | 21209701 | 21209724 | 16 | + | 26627737 | HeLa | viability after 12 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.2814665835919403 | [461] | [282,209,206] | 2 | hSpCas9 | negative selection | 1533905 | 21211525 | 21211548 | 16 | - | 26627737 | HeLa | viability after 12 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -0.3140668980834631 | [486] | [161,120,206] | -3 | hSpCas9 | negative selection | 1533906 | 21206877 | 21206900 | 16 | - | 26627737 | HeLa | viability after 15 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | 0.26576556519187255 | [555] | [193,476,135] | 2 | hSpCas9 | negative selection | 1616219 | 21209701 | 21209724 | 16 | + | 26627737 | HeLa | viability after 15 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.6306624616774984 | [461] | [347,207,318] | 5 | hSpCas9 | negative selection | 1616220 | 21211525 | 21211548 | 16 | - | 26627737 | HeLa | viability after 15 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -1.0247433032510773 | [486] | [151,85,49] | -7 | hSpCas9 | negative selection | 1616221 | 21206877 | 21206900 | 16 | - | 26627737 | HeLa | viability after 18 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | 0.22837649077247235 | [555] | [122,386,135] | 2 | hSpCas9 | negative selection | 1698534 | 21209701 | 21209724 | 16 | + | 26627737 | HeLa | viability after 18 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.5985201721316286 | [461] | [221,170,318] | 5 | hSpCas9 | negative selection | 1698535 | 21211525 | 21211548 | 16 | - | 26627737 | HeLa | viability after 18 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -1.0092631983426503 | [486] | [104,69,49] | -7 | hSpCas9 | negative selection | 1698536 | 21206877 | 21206900 | 16 | - | 26627737 | HCT116 | viability after 6 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | -0.08965477498497709 | [1039] | [152,153] | 0 | hSpCas9 | negative selection | 1780849 | 21209701 | 21209724 | 16 | + | 26627737 | HCT116 | viability after 6 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.07336276246817142 | [798] | [233,75] | 0 | hSpCas9 | negative selection | 1780850 | 21211525 | 21211548 | 16 | - | 26627737 | HCT116 | viability after 6 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | 0.6974718530664165 | [359] | [94,89] | 4 | hSpCas9 | negative selection | 1780851 | 21206877 | 21206900 | 16 | - | 26627737 | HCT116 | viability after 8 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | 0.6922427394123455 | [319] | [275,163,412] | 6 | hSpCas9 | negative selection | 1863164 | 21209701 | 21209724 | 16 | + | 26627737 | HCT116 | viability after 8 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.42340795724393504 | [389] | [299,291,272] | 4 | hSpCas9 | negative selection | 1863165 | 21211525 | 21211548 | 16 | - | 26627737 | HCT116 | viability after 8 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | 0.9777362815280572 | [134] | [206,121,111] | 8 | hSpCas9 | negative selection | 1863166 | 21206877 | 21206900 | 16 | - | 26627737 | HCT116 | viability after 9 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | -0.13783049959153426 | [1039] | [281,228] | -1 | hSpCas9 | negative selection | 1945479 | 21209701 | 21209724 | 16 | + | 26627737 | HCT116 | viability after 9 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | -0.23750325519032303 | [798] | [290,93] | -2 | hSpCas9 | negative selection | 1945480 | 21211525 | 21211548 | 16 | - | 26627737 | HCT116 | viability after 9 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | 0.11370140133516538 | [359] | [122,88] | 0 | hSpCas9 | negative selection | 1945481 | 21206877 | 21206900 | 16 | - | 26627737 | HCT116 | viability after 12 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | -0.08395566411575366 | [319] | [182,164,125] | -1 | hSpCas9 | negative selection | 2027794 | 21209701 | 21209724 | 16 | + | 26627737 | HCT116 | viability after 12 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.5913141767804841 | [389] | [376,416,128] | 5 | hSpCas9 | negative selection | 2027795 | 21211525 | 21211548 | 16 | - | 26627737 | HCT116 | viability after 12 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | 0.3803531054506978 | [134] | [129,61,80] | 4 | hSpCas9 | negative selection | 2027796 | 21206877 | 21206900 | 16 | - | 26627737 | HCT116 | viability after 15 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | 0.06363494845329705 | [319] | [268,78,236] | 0 | hSpCas9 | negative selection | 2110109 | 21209701 | 21209724 | 16 | + | 26627737 | HCT116 | viability after 15 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.7671176021348025 | [389] | [454,439,258] | 6 | hSpCas9 | negative selection | 2110110 | 21211525 | 21211548 | 16 | - | 26627737 | HCT116 | viability after 15 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | 0.9941288557765868 | [134] | [100,135,218] | 8 | hSpCas9 | negative selection | 2110111 | 21206877 | 21206900 | 16 | - | 26627737 | HCT116 | viability after 18 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | 0.3851418303910622 | [319] | [246,158,202] | 3 | hSpCas9 | negative selection | 2192424 | 21209701 | 21209724 | 16 | + | 26627737 | HCT116 | viability after 18 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 1.2408132859265144 | [389] | [411,585,323] | 8 | hSpCas9 | negative selection | 2192425 | 21211525 | 21211548 | 16 | - | 26627737 | HCT116 | viability after 18 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | 0.7171097968142746 | [134] | [183,48,91] | 6 | hSpCas9 | negative selection | 2192426 | 21206878 | 21206901 | 16 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | ATGCAAGTAGAAGAGACCCAGGG | ZP2 | ENSG00000103310 | 0.24820334016487222 | [6,5] | [6,5] | 5 | hSpCas9 | positive selection | 3035652 | 21211493 | 21211516 | 16 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CCTGCATTGAACCAGCCTGAGGG | ZP2 | ENSG00000103310 | 0.2092805876816713 | [3,2] | [3,1] | 4 | hSpCas9 | positive selection | 3035653 | 21211345 | 21211368 | 16 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GGAGTTCCCTGAAGTCACAAGGG | ZP2 | ENSG00000103310 | -0.04234521636610614 | [3,3] | [3,2] | 0 | hSpCas9 | positive selection | 3035654 | 21206878 | 21206901 | 16 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | ATGCAAGTAGAAGAGACCCAGGG | ZP2 | ENSG00000103310 | 0.2658304249266944 | [6,6] | [6,4] | 5 | hSpCas9 | positive selection | 3103510 | 21211493 | 21211516 | 16 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CCTGCATTGAACCAGCCTGAGGG | ZP2 | ENSG00000103310 | 0.3957227244921042 | [3,3] | [1,3] | 7 | hSpCas9 | positive selection | 3103511 | 21211345 | 21211368 | 16 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GGAGTTCCCTGAAGTCACAAGGG | ZP2 | ENSG00000103310 | -0.05400725249796264 | [3,3] | [4,0] | 0 | hSpCas9 | positive selection | 3103512 | 21211325 | 21211348 | | - | 24336571 | A375 | resistance to PLX after 7 days | CTCCATAGATGTTTCTCAGTTGG | ZP2 | ENSG00000103310 | -0.2902598720876733 | [17,16] | [13,13] | -8 | hSpCas9 | positive selection | 3158407 | 21210138 | 21210161 | | - | 24336571 | A375 | resistance to PLX after 7 days | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | -0.04368464349483003 | [6,5] | [5,6] | -1 | hSpCas9 | positive selection | 3158408 | 21211351 | 21211374 | | - | 24336571 | A375 | resistance to PLX after 7 days | TTCTTCGCCCTTGTGACTTCAGG | ZP2 | ENSG00000103310 | -0.19125717450999224 | [35,33] | [30,29] | -6 | hSpCas9 | positive selection | 3158409 | 21211325 | 21211348 | | - | 24336571 | A375 | resistance to PLX after 14 days | CTCCATAGATGTTTCTCAGTTGG | ZP2 | ENSG00000103310 | 0.08656818484066417 | [13,10] | [6,4] | 1 | hSpCas9 | positive selection | 3216200 | 21210138 | 21210161 | | - | 24336571 | A375 | resistance to PLX after 14 days | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.44889025062290766 | [5,5] | [3,3] | 4 | hSpCas9 | positive selection | 3216201 | 21211351 | 21211374 | | - | 24336571 | A375 | resistance to PLX after 14 days | TTCTTCGCCCTTGTGACTTCAGG | ZP2 | ENSG00000103310 | -0.9952122220945676 | [38,32] | [7,7] | -9 | hSpCas9 | positive selection | 3216202 | 21211325 | 21211348 | | - | 24336571 | A375 | viability after 7 days | CTCCATAGATGTTTCTCAGTTGG | ZP2 | ENSG00000103310 | 0.15679556809696882 | [16] | [17,16] | 2 | hSpCas9 | negative selection | 3273993 | 21210138 | 21210161 | | - | 24336571 | A375 | viability after 7 days | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.22198828869162024 | [5] | [6,5] | 3 | hSpCas9 | negative selection | 3273994 | 21211351 | 21211374 | | - | 24336571 | A375 | viability after 7 days | TTCTTCGCCCTTGTGACTTCAGG | ZP2 | ENSG00000103310 | 0.5797649874185717 | [23] | [35,33] | 8 | hSpCas9 | negative selection | 3273995 | 21211325 | 21211348 | | - | 24336571 | A375 | viability after 14 days | CTCCATAGATGTTTCTCAGTTGG | ZP2 | ENSG00000103310 | -0.29920680602709765 | [16] | [13,10] | -4 | hSpCas9 | negative selection | 3331786 | 21210138 | 21210161 | | - | 24336571 | A375 | viability after 14 days | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.11887117969601113 | [5] | [5,5] | 1 | hSpCas9 | negative selection | 3331787 | 21211351 | 21211374 | | - | 24336571 | A375 | viability after 14 days | TTCTTCGCCCTTGTGACTTCAGG | ZP2 | ENSG00000103310 | 0.6502407979010936 | [23] | [38,32] | 8 | hSpCas9 | negative selection | 3331788 | 21206884 | 21206907 | 16 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 1.7337642553888224 | [45,45] | [0,0] | 7 | hSpCas9 | positive selection | 3403773 | 21211371 | 21211394 | 16 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.2264895658184215 | [178,178] | [0,0] | -1 | hSpCas9 | positive selection | 3403774 | 21206922 | 21206945 | 16 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.48914188666890873 | [108,108] | [0,0] | 2 | hSpCas9 | positive selection | 3403775 | 21206878 | 21206901 | 16 | - | 26780180 | HT29 | viability (Avana library 4 designs) | ATGCAAGTAGAAGAGACCCAGGG | ZP2 | ENSG00000103310 | 0.324412308786815 | [] | [] | 1 | hSpCas9 | negative selection | 3475010 | 21211492 | 21211515 | 16 | + | 26780180 | HT29 | viability (Avana library 4 designs) | CCTGCATTGAACCAGCCTGAGGG | ZP2 | ENSG00000103310 | 1.15202056251695 | [] | [] | 4 | hSpCas9 | negative selection | 3475011 | 21211344 | 21211367 | 16 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GGAGTTCCCTGAAGTCACAAGGG | ZP2 | ENSG00000103310 | 0.531497852160235 | [] | [] | 2 | hSpCas9 | negative selection | 3475012 | 21211344 | 21211367 | 16 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGAGTTCCCTGAAGTCACAAGGG | ZP2 | ENSG00000103310 | -0.0219887731796363 | [] | [] | 0 | hSpCas9 | negative selection | 3583578 | 21206878 | 21206901 | 16 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ATGCAAGTAGAAGAGACCCAGGG | ZP2 | ENSG00000103310 | 2.1929218684054 | [] | [] | 3 | hSpCas9 | negative selection | 3583579 | 21211492 | 21211515 | 16 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CCTGCATTGAACCAGCCTGAGGG | ZP2 | ENSG00000103310 | 1.42981197292002 | [] | [] | 2 | hSpCas9 | negative selection | 3583580 | 21206983 | 21207006 | 16 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCTATCTGTACACAGCATGGTGG | ZP2 | ENSG00000103310 | -1.4808775876257 | [] | [] | -2 | hSpCas9 | negative selection | 3583581 | 21211344 | 21211367 | 16 | + | 26780180 | A375 | viability (Avana lentiGuide) | GGAGTTCCCTGAAGTCACAAGGG | ZP2 | ENSG00000103310 | -4.86184794590292 | [] | [] | -8 | hSpCas9 | negative selection | 3692237 | 21206878 | 21206901 | 16 | - | 26780180 | A375 | viability (Avana lentiGuide) | ATGCAAGTAGAAGAGACCCAGGG | ZP2 | ENSG00000103310 | 1.69500716747614 | [] | [] | 2 | hSpCas9 | negative selection | 3692238 | 21211492 | 21211515 | 16 | + | 26780180 | A375 | viability (Avana lentiGuide) | CCTGCATTGAACCAGCCTGAGGG | ZP2 | ENSG00000103310 | -2.86950847824115 | [] | [] | -5 | hSpCas9 | negative selection | 3692239 | 21206983 | 21207006 | 16 | - | 26780180 | A375 | viability (Avana lentiGuide) | GCTATCTGTACACAGCATGGTGG | ZP2 | ENSG00000103310 | -0.0717224823356017 | [] | [] | 0 | hSpCas9 | negative selection | 3692240 | 21211344 | 21211367 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGAGTTCCCTGAAGTCACAAGGG | ZP2 | ENSG00000103310 | 0.09040241681556363 | [4] | [5,4] | 2 | hSpCas9 | positive selection | 3800844 | 21206878 | 21206901 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ATGCAAGTAGAAGAGACCCAGGG | ZP2 | ENSG00000103310 | 0.1788057177834516 | [7] | [7,8] | 5 | hSpCas9 | positive selection | 3800845 | 21211492 | 21211515 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CCTGCATTGAACCAGCCTGAGGG | ZP2 | ENSG00000103310 | -0.16278181485803006 | [4] | [4,3] | -3 | hSpCas9 | positive selection | 3800846 | 21206983 | 21207006 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCTATCTGTACACAGCATGGTGG | ZP2 | ENSG00000103310 | 0.0148031818511196 | [5] | [4,5] | 0 | hSpCas9 | positive selection | 3800847 | 21211344 | 21211367 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGAGTTCCCTGAAGTCACAAGGG | ZP2 | ENSG00000103310 | -0.32457033129647883 | [5] | [4,2] | -4 | hSpCas9 | positive selection | 3909451 | 21206878 | 21206901 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ATGCAAGTAGAAGAGACCCAGGG | ZP2 | ENSG00000103310 | 0.16458592296714136 | [7] | [7,6] | 4 | hSpCas9 | positive selection | 3909452 | 21211492 | 21211515 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CCTGCATTGAACCAGCCTGAGGG | ZP2 | ENSG00000103310 | 0.15274172402218766 | [4] | [3,5] | 3 | hSpCas9 | positive selection | 3909453 | 21206983 | 21207006 | 16 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCTATCTGTACACAGCATGGTGG | ZP2 | ENSG00000103310 | -0.07468004976552517 | [5] | [3,4] | -1 | hSpCas9 | positive selection | 3909454 | 21206922 | 21206945 | 16 | + | 26780180 | A375 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 1.22179368366545 | [] | [] | 6 | hSpCas9 | negative selection | 4017405 | 21211371 | 21211394 | 16 | + | 26780180 | A375 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | 1.05462713734337 | [] | [] | 5 | hSpCas9 | negative selection | 4017406 | 21210170 | 21210193 | 16 | - | 26780180 | A375 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.67195884753063 | [] | [] | 2 | hSpCas9 | negative selection | 4017407 | 21209684 | 21209707 | 16 | - | 26780180 | A375 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 1.86736781860032 | [] | [] | 9 | hSpCas9 | negative selection | 4017408 | 21206884 | 21206907 | 16 | + | 26780180 | A375 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 1.13420607698048 | [] | [] | 6 | hSpCas9 | negative selection | 4017409 | 21210138 | 21210161 | 16 | - | 26780180 | A375 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 1.43184436507082 | [] | [] | 8 | hSpCas9 | negative selection | 4017410 | 21206922 | 21206945 | 16 | + | 26780180 | HT29 | viability (GeCKOv2 library) | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 1.66803267987358 | [] | [] | 8 | hSpCas9 | negative selection | 4125371 | 21211371 | 21211394 | 16 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | 1.47002777375894 | [] | [] | 7 | hSpCas9 | negative selection | 4125372 | 21210170 | 21210193 | 16 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.80706836437905 | [] | [] | 3 | hSpCas9 | negative selection | 4125373 | 21209684 | 21209707 | 16 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 1.27206139655845 | [] | [] | 6 | hSpCas9 | negative selection | 4125374 | 21206884 | 21206907 | 16 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.85562017281785 | [] | [] | 3 | hSpCas9 | negative selection | 4125375 | 21210138 | 21210161 | 16 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 1.75031615591239 | [] | [] | 8 | hSpCas9 | negative selection | 4125376 | 21211325 | 21211348 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CTCCATAGATGTTTCTCAGTTGG | ZP2 | ENSG00000103310 | 0.07454405161906645 | [3] | [2,2] | 2 | hSpCas9 | positive selection | 4185671 | 21210138 | 21210161 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | -0.16393188910497136 | [3] | [1,1] | -4 | hSpCas9 | positive selection | 4185672 | 21211351 | 21211374 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TTCTTCGCCCTTGTGACTTCAGG | ZP2 | ENSG00000103310 | -0.01955267852826073 | [4] | [2,2] | 0 | hSpCas9 | positive selection | 4185673 | 21211325 | 21211348 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CTCCATAGATGTTTCTCAGTTGG | ZP2 | ENSG00000103310 | 0.9234157122419762 | [3] | [1,4,0,3] | 6 | hSpCas9 | positive selection | 4249693 | 21210138 | 21210161 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | -0.2592212344020052 | [2] | [0,0,0,0] | -4 | hSpCas9 | positive selection | 4249694 | 21211351 | 21211374 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TTCTTCGCCCTTGTGACTTCAGG | ZP2 | ENSG00000103310 | 1.0295463805535576 | [4] | [3,4,3,3] | 7 | hSpCas9 | positive selection | 4249695 | 21210170 | 21210193 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.5949238627957425 | [2] | [2,3] | 9 | hSpCas9 | positive selection | 4310567 | 21209684 | 21209707 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | -0.0781369541864324 | [3] | [2,2] | -1 | hSpCas9 | positive selection | 4310568 | 21210138 | 21210161 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | -0.3603054760030579 | [2] | [1,0] | -6 | hSpCas9 | positive selection | 4310569 | 21206884 | 21206907 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.7670477649463279 | [1] | [0,0] | -9 | hSpCas9 | positive selection | 4374814 | 21211371 | 21211394 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | 0.4471803737927075 | [2] | [2,3] | 8 | hSpCas9 | positive selection | 4374815 | 21206922 | 21206945 | 16 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.09394240677123913 | [2] | [2,1] | 2 | hSpCas9 | positive selection | 4374816 | 21209646 | 21209668 | 16 | + | 27760321 | OCIAML3 | viability | GTTATCATAGGTAGCCCTCAGG | ZP2 | ENSG00000103310 | 0.5841267114042329 | [291,292] | [334,355] | 7 | hSpCas9 | negative selection | 4458179 | 21209702 | 21209724 | 16 | + | 27760321 | OCIAML3 | viability | TCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.20018972311452476 | [355,287] | [272,306] | 2 | hSpCas9 | negative selection | 4458180 | 21210177 | 21210199 | 16 | + | 27760321 | OCIAML3 | viability | TCGCAAGTGACAGTGCCTAAGG | ZP2 | ENSG00000103310 | 0.32994710892537493 | [507,398] | [395,503] | 4 | hSpCas9 | negative selection | 4458181 | 21209646 | 21209668 | 16 | + | 27760321 | OCIAML2 | viability | GTTATCATAGGTAGCCCTCAGG | ZP2 | ENSG00000103310 | 0.36881263789312635 | [291,292] | [240,392] | 5 | hSpCas9 | negative selection | 4541642 | 21209702 | 21209724 | 16 | + | 27760321 | OCIAML2 | viability | TCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.9290555229078109 | [355,287] | [469,523] | 9 | hSpCas9 | negative selection | 4541643 | 21210177 | 21210199 | 16 | + | 27760321 | OCIAML2 | viability | TCGCAAGTGACAGTGCCTAAGG | ZP2 | ENSG00000103310 | -0.10896475979043062 | [507,398] | [346,325] | -1 | hSpCas9 | negative selection | 4541644 | 21209646 | 21209668 | 16 | + | 27760321 | MV411 | viability | GTTATCATAGGTAGCCCTCAGG | ZP2 | ENSG00000103310 | 0.24061256231371736 | [291,292] | [28,528] | 1 | hSpCas9 | negative selection | 4625105 | 21209702 | 21209724 | 16 | + | 27760321 | MV411 | viability | TCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | -1.5185306709899078 | [355,287] | [34,131] | -7 | hSpCas9 | negative selection | 4625106 | 21210177 | 21210199 | 16 | + | 27760321 | MV411 | viability | TCGCAAGTGACAGTGCCTAAGG | ZP2 | ENSG00000103310 | -0.9869677840733347 | [507,398] | [145,155] | -6 | hSpCas9 | negative selection | 4625107 | 21209646 | 21209668 | 16 | + | 27760321 | HL60 | viability | GTTATCATAGGTAGCCCTCAGG | ZP2 | ENSG00000103310 | 0.1699454252860843 | [291,292] | [210,331] | 2 | hSpCas9 | negative selection | 4708568 | 21209702 | 21209724 | 16 | + | 27760321 | HL60 | viability | TCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.7151022879841666 | [355,287] | [411,447] | 7 | hSpCas9 | negative selection | 4708569 | 21210177 | 21210199 | 16 | + | 27760321 | HL60 | viability | TCGCAAGTGACAGTGCCTAAGG | ZP2 | ENSG00000103310 | 0.2800740861760171 | [507,398] | [458,433] | 3 | hSpCas9 | negative selection | 4708570 | 21209646 | 21209668 | 16 | + | 27760321 | HT1080 | viability | GTTATCATAGGTAGCCCTCAGG | ZP2 | ENSG00000103310 | -1.9284844366546674 | [292,228] | [33,19] | -6 | hSpCas9 | negative selection | 4792031 | 21209702 | 21209724 | 16 | + | 27760321 | HT1080 | viability | TCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.7922052144317657 | [287,224] | [133,223] | 4 | hSpCas9 | negative selection | 4792032 | 21210177 | 21210199 | 16 | + | 27760321 | HT1080 | viability | TCGCAAGTGACAGTGCCTAAGG | ZP2 | ENSG00000103310 | 0.3287420190735789 | [398,311] | [185,168] | 1 | hSpCas9 | negative selection | 4792033 | 21209646 | 21209668 | 16 | + | 27760321 | HT29 | viability after 7 days | GTTATCATAGGTAGCCCTCAGG | ZP2 | ENSG00000103310 | -0.46262369243371054 | [292,228] | [215,192,314] | -6 | hSpCas9 | negative selection | 4875494 | 21209702 | 21209724 | 16 | + | 27760321 | HT29 | viability after 7 days | TCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.580261252071382 | [287,224] | [198,564,666] | 8 | hSpCas9 | negative selection | 4875495 | 21210177 | 21210199 | 16 | + | 27760321 | HT29 | viability after 7 days | TCGCAAGTGACAGTGCCTAAGG | ZP2 | ENSG00000103310 | 0.83531225866396 | [398,311] | [670,713,1032] | 9 | hSpCas9 | negative selection | 4875496 | 21209646 | 21209668 | 16 | + | 27760321 | HT29 | viability after 25 days | GTTATCATAGGTAGCCCTCAGG | ZP2 | ENSG00000103310 | -0.5642428478924171 | [292,228] | [141,201,271] | -5 | hSpCas9 | negative selection | 4958957 | 21209702 | 21209724 | 16 | + | 27760321 | HT29 | viability after 25 days | TCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.11291195654558595 | [287,224] | [153,453,356] | 1 | hSpCas9 | negative selection | 4958958 | 21210177 | 21210199 | 16 | + | 27760321 | HT29 | viability after 25 days | TCGCAAGTGACAGTGCCTAAGG | ZP2 | ENSG00000103310 | 1.0948092313925557 | [398,311] | [844,680,1101] | 9 | hSpCas9 | negative selection | 4958959 | 21209646 | 21209668 | 16 | + | 27760321 | HT29 | viability after 22 days | GTTATCATAGGTAGCCCTCAGG | ZP2 | ENSG00000103310 | -0.43207761188462895 | [292,228] | [216,245,207] | -4 | hSpCas9 | negative selection | 5042420 | 21209702 | 21209724 | 16 | + | 27760321 | HT29 | viability after 22 days | TCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.45052373895095715 | [287,224] | [326,570,318] | 5 | hSpCas9 | negative selection | 5042421 | 21210177 | 21210199 | 16 | + | 27760321 | HT29 | viability after 22 days | TCGCAAGTGACAGTGCCTAAGG | ZP2 | ENSG00000103310 | 0.8281786619509637 | [398,311] | [677,533,980] | 8 | hSpCas9 | negative selection | 5042422 | 21209646 | 21209668 | 16 | + | 27760321 | HT29 | viability after 19 days | GTTATCATAGGTAGCCCTCAGG | ZP2 | ENSG00000103310 | -0.3441157410111975 | [292,228] | [127,58,496] | -3 | hSpCas9 | negative selection | 5125883 | 21209702 | 21209724 | 16 | + | 27760321 | HT29 | viability after 19 days | TCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.0004698631655916663 | [287,224] | [471,323,109] | 0 | hSpCas9 | negative selection | 5125884 | 21210177 | 21210199 | 16 | + | 27760321 | HT29 | viability after 19 days | TCGCAAGTGACAGTGCCTAAGG | ZP2 | ENSG00000103310 | 1.0490578243067012 | [398,311] | [781,696,1030] | 9 | hSpCas9 | negative selection | 5125885 | 21209646 | 21209668 | 16 | + | 27760321 | HT29 | viability after 16 days | GTTATCATAGGTAGCCCTCAGG | ZP2 | ENSG00000103310 | 0.2907092290260733 | [292,228] | [572,280,239] | 3 | hSpCas9 | negative selection | 5209346 | 21209702 | 21209724 | 16 | + | 27760321 | HT29 | viability after 16 days | TCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.21195241934814135 | [287,224] | [343,380,271] | 2 | hSpCas9 | negative selection | 5209347 | 21210177 | 21210199 | 16 | + | 27760321 | HT29 | viability after 16 days | TCGCAAGTGACAGTGCCTAAGG | ZP2 | ENSG00000103310 | 0.6404093846302216 | [398,311] | [962,330,605] | 7 | hSpCas9 | negative selection | 5209348 | 21209646 | 21209668 | 16 | + | 27760321 | HT29 | viability after 13 days | GTTATCATAGGTAGCCCTCAGG | ZP2 | ENSG00000103310 | -0.47285013409055837 | [292,228] | [157,232,260] | -5 | hSpCas9 | negative selection | 5292809 | 21209702 | 21209724 | 16 | + | 27760321 | HT29 | viability after 13 days | TCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | -0.1735284217131972 | [287,224] | [91,368,326] | -2 | hSpCas9 | negative selection | 5292810 | 21210177 | 21210199 | 16 | + | 27760321 | HT29 | viability after 13 days | TCGCAAGTGACAGTGCCTAAGG | ZP2 | ENSG00000103310 | 0.6153125835015975 | [398,311] | [558,540,785] | 7 | hSpCas9 | negative selection | 5292811 | 21209646 | 21209668 | 16 | + | 27760321 | HT29 | viability after 10 days | GTTATCATAGGTAGCCCTCAGG | ZP2 | ENSG00000103310 | -0.6040683702206837 | [292,228] | [161,233,246] | -6 | hSpCas9 | negative selection | 5376272 | 21209702 | 21209724 | 16 | + | 27760321 | HT29 | viability after 10 days | TCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.4034351124349176 | [287,224] | [423,367,475] | 5 | hSpCas9 | negative selection | 5376273 | 21210177 | 21210199 | 16 | + | 27760321 | HT29 | viability after 10 days | TCGCAAGTGACAGTGCCTAAGG | ZP2 | ENSG00000103310 | 0.60252468135583 | [398,311] | [481,940,607] | 7 | hSpCas9 | negative selection | 5376274 | 21209646 | 21209668 | 16 | + | 27760321 | MOLM13 | viability | GTTATCATAGGTAGCCCTCAGG | ZP2 | ENSG00000103310 | -0.9280796610295532 | [291,292] | [126,52] | -5 | hSpCas9 | negative selection | 5459735 | 21209702 | 21209724 | 16 | + | 27760321 | MOLM13 | viability | TCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | -0.4848645167614908 | [355,287] | [140,118] | -3 | hSpCas9 | negative selection | 5459736 | 21210177 | 21210199 | 16 | + | 27760321 | MOLM13 | viability | TCGCAAGTGACAGTGCCTAAGG | ZP2 | ENSG00000103310 | -0.2833647179924764 | [507,398] | [304,126] | -2 | hSpCas9 | negative selection | 5459737 | 21211188 | 21211211 | 16 | + | 27661255 | K562 | viability | GTAATAAAGGGGGTGAATGGAGG | ZP2 | ENSG00000103310 | 0.08405060485755211 | [1028,1270] | [1016,929] | 3 | dCas9-KRAB | negative selection | 5526006 | 21211485 | 21211508 | 16 | - | 27661255 | K562 | viability | GCTGGTTCAATGCAGGCTGGAGG | ZP2 | ENSG00000103310 | 0.07204988959410108 | [830,1016] | [832,721] | 2 | dCas9-KRAB | negative selection | 5526007 | 21210170 | 21210193 | 16 | - | 27260156 | BXPC3 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.580080106799102 | [343] | [541,397,591,635] | 9 | hSpCas9 | negative selection | 5583027 | 21209684 | 21209707 | 16 | - | 27260156 | BXPC3 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.18747362503650078 | [674] | [864,696,780,873] | 4 | hSpCas9 | negative selection | 5583028 | 21210138 | 21210161 | 16 | - | 27260156 | BXPC3 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.14545263690655275 | [225] | [218,221,268,351] | 3 | hSpCas9 | negative selection | 5583029 | 21206884 | 21206907 | 16 | + | 27260156 | BXPC3 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.41184865221623257 | [142] | [107,121,126,88] | -7 | hSpCas9 | negative selection | 5647274 | 21211371 | 21211394 | 16 | + | 27260156 | BXPC3 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.2603250471966577 | [425] | [408,321,371,381] | -5 | hSpCas9 | negative selection | 5647275 | 21206922 | 21206945 | 16 | + | 27260156 | BXPC3 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.10288488184960354 | [280] | [261,302,343,363] | 2 | hSpCas9 | negative selection | 5647276 | 21210170 | 21210193 | 16 | - | 27260156 | A673 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.3547947816112802 | [343] | [613,523,491,489] | 7 | hSpCas9 | negative selection | 5704278 | 21209684 | 21209707 | 16 | - | 27260156 | A673 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.09483656289674747 | [674] | [960,883,804,818] | 2 | hSpCas9 | negative selection | 5704279 | 21210138 | 21210161 | 16 | - | 27260156 | A673 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.4333312339512908 | [225] | [435,267,364,408] | 8 | hSpCas9 | negative selection | 5704280 | 21206884 | 21206907 | 16 | + | 27260156 | A673 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.041683863498553464 | [142] | [167,232,111,151] | -1 | hSpCas9 | negative selection | 5768525 | 21211371 | 21211394 | 16 | + | 27260156 | A673 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | 0.043567941532849125 | [425] | [636,441,526,515] | 1 | hSpCas9 | negative selection | 5768526 | 21206922 | 21206945 | 16 | + | 27260156 | A673 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.04324765174122014 | [280] | [410,290,301,397] | 1 | hSpCas9 | negative selection | 5768527 | 21210170 | 21210193 | 16 | - | 27260156 | A375 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.7296929134649952 | [343] | [411,812,779,674] | 9 | hSpCas9 | negative selection | 5825529 | 21209684 | 21209707 | 16 | - | 27260156 | A375 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.3047049798089455 | [674] | [1162,946,961,833] | 4 | hSpCas9 | negative selection | 5825530 | 21210138 | 21210161 | 16 | - | 27260156 | A375 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.38666254365077257 | [225] | [202,485,320,382] | 5 | hSpCas9 | negative selection | 5825531 | 21206884 | 21206907 | 16 | + | 27260156 | A375 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.32496771174703865 | [142] | [190,363,199,113] | 5 | hSpCas9 | negative selection | 5889776 | 21211371 | 21211394 | 16 | + | 27260156 | A375 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.32827698620002466 | [425] | [364,338,359,498] | -5 | hSpCas9 | negative selection | 5889777 | 21206922 | 21206945 | 16 | + | 27260156 | A375 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.3107328996605784 | [280] | [397,451,394,389] | 4 | hSpCas9 | negative selection | 5889778 | 21210170 | 21210193 | 16 | - | 27260156 | COLO741 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.14801948137335053 | [343] | [530,464,468] | 3 | hSpCas9 | negative selection | 5946780 | 21209684 | 21209707 | 16 | - | 27260156 | COLO741 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.011482262908666163 | [674] | [913,954,749] | 0 | hSpCas9 | negative selection | 5946781 | 21210138 | 21210161 | 16 | - | 27260156 | COLO741 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.004415450757661699 | [225] | [341,301,232] | 0 | hSpCas9 | negative selection | 5946782 | 21206884 | 21206907 | 16 | + | 27260156 | COLO741 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.12341389114234214 | [142] | [210,136,245] | 2 | hSpCas9 | negative selection | 6011027 | 21211371 | 21211394 | 16 | + | 27260156 | COLO741 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.3715730217497959 | [425] | [554,375,346] | -7 | hSpCas9 | negative selection | 6011028 | 21206922 | 21206945 | 16 | + | 27260156 | COLO741 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.14278334754804245 | [280] | [413,410,366] | 3 | hSpCas9 | negative selection | 6011029 | 21210170 | 21210193 | 16 | - | 27260156 | CAL120 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.19268080135318144 | [343] | [500,463,503] | 3 | hSpCas9 | negative selection | 6068031 | 21209684 | 21209707 | 16 | - | 27260156 | CAL120 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | -0.15163764539198693 | [674] | [968,564,765] | -2 | hSpCas9 | negative selection | 6068032 | 21210138 | 21210161 | 16 | - | 27260156 | CAL120 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.17626355052440856 | [225] | [284,497,167] | 2 | hSpCas9 | negative selection | 6068033 | 21206884 | 21206907 | 16 | + | 27260156 | CAL120 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.4282279876359927 | [142] | [125,214,357] | 6 | hSpCas9 | negative selection | 6132278 | 21211371 | 21211394 | 16 | + | 27260156 | CAL120 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.7638600531769262 | [425] | [322,298,315] | -8 | hSpCas9 | negative selection | 6132279 | 21206922 | 21206945 | 16 | + | 27260156 | CAL120 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.4187342640335221 | [280] | [696,348,391] | 6 | hSpCas9 | negative selection | 6132280 | 21210170 | 21210193 | 16 | - | 27260156 | CADOES1 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.7015755333005929 | [343] | [409,446,737,484] | 9 | hSpCas9 | negative selection | 6189282 | 21209684 | 21209707 | 16 | - | 27260156 | CADOES1 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | -0.19437198362346608 | [674] | [574,581,530,504] | -3 | hSpCas9 | negative selection | 6189283 | 21210138 | 21210161 | 16 | - | 27260156 | CADOES1 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.20017322270970284 | [225] | [225,404,152,179] | 3 | hSpCas9 | negative selection | 6189284 | 21206884 | 21206907 | 16 | + | 27260156 | CADOES1 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.119160952922166 | [142] | [122,135,129,99] | -2 | hSpCas9 | negative selection | 6253529 | 21211371 | 21211394 | 16 | + | 27260156 | CADOES1 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.24901659918602329 | [425] | [539,321,164,304] | -4 | hSpCas9 | negative selection | 6253530 | 21206922 | 21206945 | 16 | + | 27260156 | CADOES1 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | -0.25148675331377124 | [280] | [312,197,169,195] | -4 | hSpCas9 | negative selection | 6253531 | 21210170 | 21210193 | 16 | - | 27260156 | EWS502 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.46949941885810736 | [343] | [701,432,479,369] | 7 | hSpCas9 | negative selection | 6310533 | 21209684 | 21209707 | 16 | - | 27260156 | EWS502 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.008549241369797955 | [674] | [789,723,581,770] | 0 | hSpCas9 | negative selection | 6310534 | 21210138 | 21210161 | 16 | - | 27260156 | EWS502 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.03529464725935272 | [225] | [252,273,246,200] | 0 | hSpCas9 | negative selection | 6310535 | 21206884 | 21206907 | 16 | + | 27260156 | EWS502 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.014640669875370271 | [142] | [142,122,178,156] | 0 | hSpCas9 | negative selection | 6374780 | 21211371 | 21211394 | 16 | + | 27260156 | EWS502 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.1144863572982622 | [425] | [327,375,477,502] | -2 | hSpCas9 | negative selection | 6374781 | 21206922 | 21206945 | 16 | + | 27260156 | EWS502 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.12702458830047536 | [280] | [291,445,307,245] | 2 | hSpCas9 | negative selection | 6374782 | 21210170 | 21210193 | 16 | - | 27260156 | EW8 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.5652342797748786 | [343] | [503,452,276,447] | 8 | hSpCas9 | negative selection | 6431784 | 21209684 | 21209707 | 16 | - | 27260156 | EW8 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.13102086987980532 | [674] | [714,621,428,669] | 2 | hSpCas9 | negative selection | 6431785 | 21210138 | 21210161 | 16 | - | 27260156 | EW8 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.18084130716284552 | [225] | [214,278,148,197] | 3 | hSpCas9 | negative selection | 6431786 | 21206884 | 21206907 | 16 | + | 27260156 | EW8 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.11981586235075081 | [142] | [131,135,60,107] | -2 | hSpCas9 | negative selection | 6496031 | 21211371 | 21211394 | 16 | + | 27260156 | EW8 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.21805300226988641 | [425] | [377,274,304,235] | -4 | hSpCas9 | negative selection | 6496032 | 21206922 | 21206945 | 16 | + | 27260156 | EW8 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.4451401013209933 | [280] | [266,280,184,521] | 7 | hSpCas9 | negative selection | 6496033 | 21210170 | 21210193 | 16 | - | 27260156 | CORL105 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.7828961658269531 | [343] | [575,493,1036,717] | 9 | hSpCas9 | negative selection | 6553035 | 21209684 | 21209707 | 16 | - | 27260156 | CORL105 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.2414520505760015 | [674] | [999,942,1016,791] | 4 | hSpCas9 | negative selection | 6553036 | 21210138 | 21210161 | 16 | - | 27260156 | CORL105 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | -0.08376210386252625 | [225] | [251,255,283,211] | -1 | hSpCas9 | negative selection | 6553037 | 21206884 | 21206907 | 16 | + | 27260156 | CORL105 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.18530362477366746 | [142] | [287,122,251,112] | 3 | hSpCas9 | negative selection | 6617282 | 21211371 | 21211394 | 16 | + | 27260156 | CORL105 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.06658678479564101 | [425] | [524,458,470,450] | -1 | hSpCas9 | negative selection | 6617283 | 21206922 | 21206945 | 16 | + | 27260156 | CORL105 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.07082233105157776 | [280] | [291,305,304,470] | 1 | hSpCas9 | negative selection | 6617284 | 21210170 | 21210193 | 16 | - | 27260156 | HS294T | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.47989938073711746 | [343] | [240,147,193,147] | 6 | hSpCas9 | negative selection | 6674286 | 21209684 | 21209707 | 16 | - | 27260156 | HS294T | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.3960832205634064 | [674] | [217,486,320,355] | 5 | hSpCas9 | negative selection | 6674287 | 21210138 | 21210161 | 16 | - | 27260156 | HS294T | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.17479886716551596 | [225] | [61,108,104,125] | 2 | hSpCas9 | negative selection | 6674288 | 21206884 | 21206907 | 16 | + | 27260156 | HS294T | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.19976842956993623 | [142] | [32,43,63,53] | -3 | hSpCas9 | negative selection | 6738533 | 21211371 | 21211394 | 16 | + | 27260156 | HS294T | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.7168325701422021 | [425] | [63,100,88,159] | -8 | hSpCas9 | negative selection | 6738534 | 21206922 | 21206945 | 16 | + | 27260156 | HS294T | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.11616239544520435 | [280] | [90,159,121,94] | 1 | hSpCas9 | negative selection | 6738535 | 21210170 | 21210193 | 16 | - | 27260156 | HCC44 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.6601085306485026 | [343] | [915,338,700,580] | 9 | hSpCas9 | negative selection | 6795537 | 21209684 | 21209707 | 16 | - | 27260156 | HCC44 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.2880506299002161 | [674] | [1039,881,859,942] | 5 | hSpCas9 | negative selection | 6795538 | 21210138 | 21210161 | 16 | - | 27260156 | HCC44 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.5966627115878937 | [225] | [243,503,494,291] | 8 | hSpCas9 | negative selection | 6795539 | 21206884 | 21206907 | 16 | + | 27260156 | HCC44 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.1427626277176337 | [142] | [143,222,183,153] | 2 | hSpCas9 | negative selection | 6859784 | 21211371 | 21211394 | 16 | + | 27260156 | HCC44 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.1914880001116285 | [425] | [482,379,285,519] | -3 | hSpCas9 | negative selection | 6859785 | 21206922 | 21206945 | 16 | + | 27260156 | HCC44 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | -0.12418681781214214 | [280] | [321,334,315,194] | -2 | hSpCas9 | negative selection | 6859786 | 21210170 | 21210193 | 16 | - | 27260156 | G402 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.7272785218825337 | [343] | [783,338,567,1059] | 8 | hSpCas9 | negative selection | 6916788 | 21209684 | 21209707 | 16 | - | 27260156 | G402 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.36973241650050304 | [674] | [961,993,663,1587] | 4 | hSpCas9 | negative selection | 6916789 | 21210138 | 21210161 | 16 | - | 27260156 | G402 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.2599673172808551 | [225] | [277,387,225,418] | 3 | hSpCas9 | negative selection | 6916790 | 21206884 | 21206907 | 16 | + | 27260156 | G402 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.39740839323310073 | [142] | [189,391,277,69] | 5 | hSpCas9 | negative selection | 6981035 | 21211371 | 21211394 | 16 | + | 27260156 | G402 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | 0.1350195079877975 | [425] | [423,402,914,510] | 1 | hSpCas9 | negative selection | 6981036 | 21206922 | 21206945 | 16 | + | 27260156 | G402 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.9909908432467628 | [280] | [1091,451,665,564] | 9 | hSpCas9 | negative selection | 6981037 | 21210170 | 21210193 | 16 | - | 27260156 | L33 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.4397486977590812 | [343] | [585,210,253,358] | 8 | hSpCas9 | negative selection | 7038039 | 21209684 | 21209707 | 16 | - | 27260156 | L33 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.10509678450104176 | [674] | [608,284,577,683] | 2 | hSpCas9 | negative selection | 7038040 | 21210138 | 21210161 | 16 | - | 27260156 | L33 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.08241288767674382 | [225] | [211,95,164,248] | 1 | hSpCas9 | negative selection | 7038041 | 21206884 | 21206907 | 16 | + | 27260156 | L33 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.2326211789198025 | [142] | [106,66,82,84] | -5 | hSpCas9 | negative selection | 7102286 | 21211371 | 21211394 | 16 | + | 27260156 | L33 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | 0.038155445206573615 | [425] | [502,157,274,421] | 0 | hSpCas9 | negative selection | 7102287 | 21206922 | 21206945 | 16 | + | 27260156 | L33 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | -0.21257021684373534 | [280] | [323,92,126,214] | -5 | hSpCas9 | negative selection | 7102288 | 21210170 | 21210193 | 16 | - | 27260156 | K562 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 1.084652453771748 | [343] | [793,607,415,764] | 9 | hSpCas9 | negative selection | 7159290 | 21209684 | 21209707 | 16 | - | 27260156 | K562 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | -0.05326649110838649 | [674] | [784,464,642,440] | 0 | hSpCas9 | negative selection | 7159291 | 21210138 | 21210161 | 16 | - | 27260156 | K562 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.46829806318133516 | [225] | [278,303,360,177] | 6 | hSpCas9 | negative selection | 7159292 | 21206884 | 21206907 | 16 | + | 27260156 | K562 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.08826739673000095 | [142] | [25,201,119,124] | -1 | hSpCas9 | negative selection | 7223537 | 21211371 | 21211394 | 16 | + | 27260156 | K562 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | 0.11098312042341169 | [425] | [300,382,554,384] | 1 | hSpCas9 | negative selection | 7223538 | 21206922 | 21206945 | 16 | + | 27260156 | K562 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.09209027187049901 | [280] | [327,193,318,226] | 1 | hSpCas9 | negative selection | 7223539 | 21210170 | 21210193 | 16 | - | 27260156 | HT29 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.39867399985787 | [343] | [433,682,513,569] | 7 | hSpCas9 | negative selection | 7280541 | 21209684 | 21209707 | 16 | - | 27260156 | HT29 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.1116756016458933 | [674] | [943,765,1009,821] | 2 | hSpCas9 | negative selection | 7280542 | 21210138 | 21210161 | 16 | - | 27260156 | HT29 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.24278550189448356 | [225] | [260,283,405,336] | 5 | hSpCas9 | negative selection | 7280543 | 21206884 | 21206907 | 16 | + | 27260156 | HT29 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.25358218392323995 | [142] | [168,148,198,75] | -5 | hSpCas9 | negative selection | 7344788 | 21211371 | 21211394 | 16 | + | 27260156 | HT29 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | 0.04143766960899231 | [425] | [479,704,594,377] | 0 | hSpCas9 | negative selection | 7344789 | 21206922 | 21206945 | 16 | + | 27260156 | HT29 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.012015431288177392 | [280] | [388,371,337,288] | 0 | hSpCas9 | negative selection | 7344790 | 21210170 | 21210193 | 16 | - | 27260156 | MHHES1 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.6531343955996334 | [343] | [958,641,482,426] | 9 | hSpCas9 | negative selection | 7401792 | 21209684 | 21209707 | 16 | - | 27260156 | MHHES1 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.15342239379281875 | [674] | [784,754,952,851] | 3 | hSpCas9 | negative selection | 7401793 | 21210138 | 21210161 | 16 | - | 27260156 | MHHES1 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.194536762961942 | [225] | [351,212,332,265] | 3 | hSpCas9 | negative selection | 7401794 | 21206884 | 21206907 | 16 | + | 27260156 | MHHES1 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.2888954310523686 | [142] | [159,175,105,97] | -5 | hSpCas9 | negative selection | 7466039 | 21211371 | 21211394 | 16 | + | 27260156 | MHHES1 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.3234940672829374 | [425] | [321,535,456,249] | -6 | hSpCas9 | negative selection | 7466040 | 21206922 | 21206945 | 16 | + | 27260156 | MHHES1 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.25789922663730297 | [280] | [378,449,406,295] | 5 | hSpCas9 | negative selection | 7466041 | 21210170 | 21210193 | 16 | - | 27260156 | MEWO | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.3780126867546439 | [343] | [577,330,376] | 7 | hSpCas9 | negative selection | 7523043 | 21209684 | 21209707 | 16 | - | 27260156 | MEWO | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.29822758715421815 | [674] | [931,674,752] | 6 | hSpCas9 | negative selection | 7523044 | 21210138 | 21210161 | 16 | - | 27260156 | MEWO | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.09390451084936302 | [225] | [250,190,239] | 2 | hSpCas9 | negative selection | 7523045 | 21206884 | 21206907 | 16 | + | 27260156 | MEWO | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.31431478234899 | [142] | [98,126,94] | -6 | hSpCas9 | negative selection | 7587290 | 21211371 | 21211394 | 16 | + | 27260156 | MEWO | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.05281210154128416 | [425] | [504,380,289] | -1 | hSpCas9 | negative selection | 7587291 | 21206922 | 21206945 | 16 | + | 27260156 | MEWO | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.4674895722177009 | [280] | [344,330,410] | 8 | hSpCas9 | negative selection | 7587292 | 21210170 | 21210193 | 16 | - | 27260156 | LNCAPCLONEFGC | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.5702299771224233 | [343] | [432,420,558,454] | 8 | hSpCas9 | negative selection | 7644294 | 21209684 | 21209707 | 16 | - | 27260156 | LNCAPCLONEFGC | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.3354785924224071 | [674] | [695,878,872,646] | 5 | hSpCas9 | negative selection | 7644295 | 21210138 | 21210161 | 16 | - | 27260156 | LNCAPCLONEFGC | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.14142397571508702 | [225] | [280,147,244,235] | 2 | hSpCas9 | negative selection | 7644296 | 21206884 | 21206907 | 16 | + | 27260156 | LNCAPCLONEFGC | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.20028190622154485 | [142] | [231,129,95,128] | 3 | hSpCas9 | negative selection | 7708541 | 21211371 | 21211394 | 16 | + | 27260156 | LNCAPCLONEFGC | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | 0.056796037770513425 | [425] | [308,338,554,430] | 0 | hSpCas9 | negative selection | 7708542 | 21206922 | 21206945 | 16 | + | 27260156 | LNCAPCLONEFGC | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.10804232442559736 | [280] | [209,286,357,254] | 1 | hSpCas9 | negative selection | 7708543 | 21210170 | 21210193 | 16 | - | 27260156 | PANC0327 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.47453595479504257 | [343] | [592,265,633,239] | 7 | hSpCas9 | negative selection | 7765545 | 21209684 | 21209707 | 16 | - | 27260156 | PANC0327 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.03394636287397679 | [674] | [620,390,806,665] | 0 | hSpCas9 | negative selection | 7765546 | 21210138 | 21210161 | 16 | - | 27260156 | PANC0327 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.8028452521374141 | [225] | [558,348,258,250] | 9 | hSpCas9 | negative selection | 7765547 | 21206884 | 21206907 | 16 | + | 27260156 | PANC0327 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.8832506057259537 | [142] | [60,20,92,105] | -8 | hSpCas9 | negative selection | 7829792 | 21211371 | 21211394 | 16 | + | 27260156 | PANC0327 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | 0.0809638350654438 | [425] | [489,278,438,415] | 1 | hSpCas9 | negative selection | 7829793 | 21206922 | 21206945 | 16 | + | 27260156 | PANC0327 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.4530776217792732 | [280] | [328,393,348,286] | 6 | hSpCas9 | negative selection | 7829794 | 21210170 | 21210193 | 16 | - | 27260156 | NCIH2009 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.9729658317399269 | [343] | [1251,920,716] | 9 | hSpCas9 | negative selection | 7886796 | 21209684 | 21209707 | 16 | - | 27260156 | NCIH2009 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.3044197799090653 | [674] | [1270,940,1304] | 4 | hSpCas9 | negative selection | 7886797 | 21210138 | 21210161 | 16 | - | 27260156 | NCIH2009 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.13376557966973335 | [225] | [423,348,280] | 1 | hSpCas9 | negative selection | 7886798 | 21206884 | 21206907 | 16 | + | 27260156 | NCIH2009 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.10153419712563605 | [142] | [422,156,104] | 1 | hSpCas9 | negative selection | 7951043 | 21211371 | 21211394 | 16 | + | 27260156 | NCIH2009 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.1266584218882518 | [425] | [569,405,665] | -2 | hSpCas9 | negative selection | 7951044 | 21206922 | 21206945 | 16 | + | 27260156 | NCIH2009 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | -0.2641821046035736 | [280] | [451,320,231] | -4 | hSpCas9 | negative selection | 7951045 | 21210170 | 21210193 | 16 | - | 27260156 | NCIH1373 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.5941214264808654 | [343] | [805,567,450,140] | 6 | hSpCas9 | negative selection | 8008047 | 21209684 | 21209707 | 16 | - | 27260156 | NCIH1373 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.28062712469231943 | [674] | [1059,709,1043,235] | 2 | hSpCas9 | negative selection | 8008048 | 21210138 | 21210161 | 16 | - | 27260156 | NCIH1373 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 1.1030938701556652 | [225] | [640,391,251,249] | 9 | hSpCas9 | negative selection | 8008049 | 21206884 | 21206907 | 16 | + | 27260156 | NCIH1373 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.5917513989515442 | [142] | [194,159,151,124] | 6 | hSpCas9 | negative selection | 8072294 | 21211371 | 21211394 | 16 | + | 27260156 | NCIH1373 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.17202526418567834 | [425] | [256,417,223,208] | -2 | hSpCas9 | negative selection | 8072295 | 21206922 | 21206945 | 16 | + | 27260156 | NCIH1373 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | -0.25983713795912655 | [280] | [343,178,170,101] | -3 | hSpCas9 | negative selection | 8072296 | 21210170 | 21210193 | 16 | - | 27260156 | PATU8902 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 1.0114562724612846 | [343] | [1501,1132,525,779] | 9 | hSpCas9 | negative selection | 8129298 | 21209684 | 21209707 | 16 | - | 27260156 | PATU8902 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.27227216373799623 | [674] | [932,914,890,1956] | 2 | hSpCas9 | negative selection | 8129299 | 21210138 | 21210161 | 16 | - | 27260156 | PATU8902 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.36621188627997936 | [225] | [385,285,321,679] | 4 | hSpCas9 | negative selection | 8129300 | 21206884 | 21206907 | 16 | + | 27260156 | PATU8902 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.156823501101522 | [142] | [22,209,118,405] | -1 | hSpCas9 | negative selection | 8193545 | 21211371 | 21211394 | 16 | + | 27260156 | PATU8902 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.5466726032525238 | [425] | [678,471,229,265] | -5 | hSpCas9 | negative selection | 8193546 | 21206922 | 21206945 | 16 | + | 27260156 | PATU8902 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | -0.21656065348303832 | [280] | [665,277,109,345] | -2 | hSpCas9 | negative selection | 8193547 | 21210170 | 21210193 | 16 | - | 27260156 | PANC1 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.6856926355890754 | [343] | [461,537,365,529] | 9 | hSpCas9 | negative selection | 8250549 | 21209684 | 21209707 | 16 | - | 27260156 | PANC1 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.023993214143707253 | [674] | [746,827,572,294] | 0 | hSpCas9 | negative selection | 8250550 | 21210138 | 21210161 | 16 | - | 27260156 | PANC1 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | -0.046356812472186704 | [225] | [269,186,186,114] | 0 | hSpCas9 | negative selection | 8250551 | 21206884 | 21206907 | 16 | + | 27260156 | PANC1 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.012818919605954271 | [142] | [70,142,176,102] | 0 | hSpCas9 | negative selection | 8314796 | 21211371 | 21211394 | 16 | + | 27260156 | PANC1 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.23562907930342472 | [425] | [354,507,196,229] | -4 | hSpCas9 | negative selection | 8314797 | 21206922 | 21206945 | 16 | + | 27260156 | PANC1 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.08384190213969167 | [280] | [316,357,150,217] | 1 | hSpCas9 | negative selection | 8314798 | 21210170 | 21210193 | 16 | - | 27260156 | PANC0813 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.644716845110573 | [343] | [816,709,454,563] | 8 | hSpCas9 | negative selection | 8371800 | 21209684 | 21209707 | 16 | - | 27260156 | PANC0813 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.5544420676323473 | [674] | [1500,1463,815,917] | 8 | hSpCas9 | negative selection | 8371801 | 21210138 | 21210161 | 16 | - | 27260156 | PANC0813 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.28288989009064225 | [225] | [324,375,382,213] | 4 | hSpCas9 | negative selection | 8371802 | 21206884 | 21206907 | 16 | + | 27260156 | PANC0813 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.07576296660144788 | [142] | [167,265,171,104] | 1 | hSpCas9 | negative selection | 8436047 | 21211371 | 21211394 | 16 | + | 27260156 | PANC0813 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.05187898907101263 | [425] | [602,449,441,447] | -1 | hSpCas9 | negative selection | 8436048 | 21206922 | 21206945 | 16 | + | 27260156 | PANC0813 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | -0.08894295116238882 | [280] | [430,189,352,279] | -1 | hSpCas9 | negative selection | 8436049 | 21210170 | 21210193 | 16 | - | 27260156 | RDES | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.5414394620639044 | [343] | [439,456,708,753] | 8 | hSpCas9 | negative selection | 8493051 | 21209684 | 21209707 | 16 | - | 27260156 | RDES | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | -0.07993231630645592 | [674] | [538,776,835,818] | -1 | hSpCas9 | negative selection | 8493052 | 21210138 | 21210161 | 16 | - | 27260156 | RDES | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.26366271304394184 | [225] | [289,289,326,342] | 4 | hSpCas9 | negative selection | 8493053 | 21206884 | 21206907 | 16 | + | 27260156 | RDES | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.03805229561439827 | [142] | [151,138,221,164] | 0 | hSpCas9 | negative selection | 8557298 | 21211371 | 21211394 | 16 | + | 27260156 | RDES | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.3035113804179056 | [425] | [259,408,434,521] | -5 | hSpCas9 | negative selection | 8557299 | 21206922 | 21206945 | 16 | + | 27260156 | RDES | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | -0.09626398834397631 | [280] | [337,243,300,314] | -2 | hSpCas9 | negative selection | 8557300 | 21210170 | 21210193 | 16 | - | 27260156 | PC3 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.1294524359212707 | [343] | [206,431,666,343] | 3 | hSpCas9 | negative selection | 8614302 | 21209684 | 21209707 | 16 | - | 27260156 | PC3 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | -0.03302087549102101 | [674] | [389,542,1249,745] | 0 | hSpCas9 | negative selection | 8614303 | 21210138 | 21210161 | 16 | - | 27260156 | PC3 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | -0.05939738814829876 | [225] | [102,171,363,323] | -1 | hSpCas9 | negative selection | 8614304 | 21206884 | 21206907 | 16 | + | 27260156 | PC3 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.24678986563118777 | [142] | [52,184,172,105] | -5 | hSpCas9 | negative selection | 8678549 | 21211371 | 21211394 | 16 | + | 27260156 | PC3 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.0905918137899627 | [425] | [217,375,804,400] | -2 | hSpCas9 | negative selection | 8678550 | 21206922 | 21206945 | 16 | + | 27260156 | PC3 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.3580036570858365 | [280] | [212,379,752,268] | 7 | hSpCas9 | negative selection | 8678551 | 21210170 | 21210193 | 16 | - | 27260156 | PATU8988T | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.8512022902827755 | [343] | [466,1274,295,412] | 9 | hSpCas9 | negative selection | 8735553 | 21209684 | 21209707 | 16 | - | 27260156 | PATU8988T | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.09534268012781522 | [674] | [602,737,685,769] | 1 | hSpCas9 | negative selection | 8735554 | 21210138 | 21210161 | 16 | - | 27260156 | PATU8988T | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.018428036312142293 | [225] | [273,266,179,163] | 0 | hSpCas9 | negative selection | 8735555 | 21206884 | 21206907 | 16 | + | 27260156 | PATU8988T | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.5466742112303931 | [142] | [48,92,87,152] | -7 | hSpCas9 | negative selection | 8799800 | 21211371 | 21211394 | 16 | + | 27260156 | PATU8988T | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | 0.1184802250603148 | [425] | [665,426,368,313] | 2 | hSpCas9 | negative selection | 8799801 | 21206922 | 21206945 | 16 | + | 27260156 | PATU8988T | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | -0.04911960169261431 | [280] | [212,238,229,374] | -1 | hSpCas9 | negative selection | 8799802 | 21210170 | 21210193 | 16 | - | 27260156 | T47D | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.46293943560537965 | [343] | [492,579,564,568] | 8 | hSpCas9 | negative selection | 8856804 | 21209684 | 21209707 | 16 | - | 27260156 | T47D | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.034656412655494684 | [674] | [845,665,838,884] | 0 | hSpCas9 | negative selection | 8856805 | 21210138 | 21210161 | 16 | - | 27260156 | T47D | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.18034967031921956 | [225] | [295,226,381,292] | 4 | hSpCas9 | negative selection | 8856806 | 21206884 | 21206907 | 16 | + | 27260156 | T47D | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.09502034758462719 | [142] | [142,101,152,232] | -2 | hSpCas9 | negative selection | 8921051 | 21211371 | 21211394 | 16 | + | 27260156 | T47D | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.24694878349430263 | [425] | [486,361,369,460] | -5 | hSpCas9 | negative selection | 8921052 | 21206922 | 21206945 | 16 | + | 27260156 | T47D | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.29757819888037507 | [280] | [521,342,384,363] | 6 | hSpCas9 | negative selection | 8921053 | 21210170 | 21210193 | 16 | - | 27260156 | SU8686 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.4706620637399775 | [343] | [407,404,498,614] | 7 | hSpCas9 | negative selection | 8978055 | 21209684 | 21209707 | 16 | - | 27260156 | SU8686 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.48128544891221703 | [674] | [978,717,985,1097] | 7 | hSpCas9 | negative selection | 8978056 | 21210138 | 21210161 | 16 | - | 27260156 | SU8686 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | -0.04376078586686649 | [225] | [168,130,246,361] | -1 | hSpCas9 | negative selection | 8978057 | 21206884 | 21206907 | 16 | + | 27260156 | SU8686 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.07949204946502264 | [142] | [115,53,165,303] | 1 | hSpCas9 | negative selection | 9042302 | 21211371 | 21211394 | 16 | + | 27260156 | SU8686 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.23567076495469338 | [425] | [358,345,326,408] | -4 | hSpCas9 | negative selection | 9042303 | 21206922 | 21206945 | 16 | + | 27260156 | SU8686 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.30876874036280627 | [280] | [338,378,284,373] | 5 | hSpCas9 | negative selection | 9042304 | 21210170 | 21210193 | 16 | - | 27260156 | SKES1 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.3640214653361577 | [343] | [322,528,413,484] | 7 | hSpCas9 | negative selection | 9099306 | 21209684 | 21209707 | 16 | - | 27260156 | SKES1 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.11361981387249065 | [674] | [872,645,719,682] | 2 | hSpCas9 | negative selection | 9099307 | 21210138 | 21210161 | 16 | - | 27260156 | SKES1 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | -0.24215734903636843 | [225] | [227,175,157,200] | -5 | hSpCas9 | negative selection | 9099308 | 21206884 | 21206907 | 16 | + | 27260156 | SKES1 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.962482392988754 | [142] | [63,74,58,90] | -9 | hSpCas9 | negative selection | 9163553 | 21211371 | 21211394 | 16 | + | 27260156 | SKES1 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.11925866448136 | [425] | [336,357,375,468] | -3 | hSpCas9 | negative selection | 9163554 | 21206922 | 21206945 | 16 | + | 27260156 | SKES1 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.22510375773282199 | [280] | [457,342,358,183] | 5 | hSpCas9 | negative selection | 9163555 | 21210170 | 21210193 | 16 | - | 27260156 | TOV112D | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.617917383873544 | [343] | [502,756,375,531] | 9 | hSpCas9 | negative selection | 9220557 | 21209684 | 21209707 | 16 | - | 27260156 | TOV112D | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.3288909675142685 | [674] | [627,1193,484,1145] | 6 | hSpCas9 | negative selection | 9220558 | 21210138 | 21210161 | 16 | - | 27260156 | TOV112D | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.3793605437579445 | [225] | [285,325,339,233] | 7 | hSpCas9 | negative selection | 9220559 | 21206884 | 21206907 | 16 | + | 27260156 | TOV112D | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.03894532687477548 | [142] | [171,163,119,110] | 0 | hSpCas9 | negative selection | 9284804 | 21211371 | 21211394 | 16 | + | 27260156 | TOV112D | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.3312093073877167 | [425] | [216,554,329,297] | -6 | hSpCas9 | negative selection | 9284805 | 21206922 | 21206945 | 16 | + | 27260156 | TOV112D | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.09900170883445625 | [280] | [227,407,169,415] | 2 | hSpCas9 | negative selection | 9284806 | 21210170 | 21210193 | 16 | - | 27260156 | TC71 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.4105413276113746 | [343] | [513,529,407,511] | 8 | hSpCas9 | negative selection | 9341808 | 21209684 | 21209707 | 16 | - | 27260156 | TC71 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | -0.021901199900662083 | [674] | [774,708,704,656] | 0 | hSpCas9 | negative selection | 9341809 | 21210138 | 21210161 | 16 | - | 27260156 | TC71 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.33142142431077115 | [225] | [254,383,309,268] | 7 | hSpCas9 | negative selection | 9341810 | 21206884 | 21206907 | 16 | + | 27260156 | TC71 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | -0.1819114712183194 | [142] | [96,150,103,193] | -5 | hSpCas9 | negative selection | 9406055 | 21211371 | 21211394 | 16 | + | 27260156 | TC71 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | 0.2091787900856344 | [425] | [596,534,496,478] | 5 | hSpCas9 | negative selection | 9406056 | 21206922 | 21206945 | 16 | + | 27260156 | TC71 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.0748971201259645 | [280] | [218,317,314,425] | 2 | hSpCas9 | negative selection | 9406057 | 21210170 | 21210193 | 16 | - | 27260156 | TC32 | viability | GCACTGTCACTTGCGATGAAAGG | ZP2 | ENSG00000103310 | 0.494307661228716 | [343] | [365,328,563,623] | 8 | hSpCas9 | negative selection | 9463059 | 21209684 | 21209707 | 16 | - | 27260156 | TC32 | viability | GCCGAACTGCACTTACATCCTGG | ZP2 | ENSG00000103310 | 0.10893622270647918 | [674] | [721,409,920,789] | 2 | hSpCas9 | negative selection | 9463060 | 21210138 | 21210161 | 16 | - | 27260156 | TC32 | viability | GTGGAGTTCCCAAGCAGTCCTGG | ZP2 | ENSG00000103310 | 0.20258684305734165 | [225] | [224,200,336,233] | 3 | hSpCas9 | negative selection | 9463061 | 21206884 | 21206907 | 16 | + | 27260156 | TC32 | viability | GTCTCTTCTACTTGCATAGCTGG | ZP2 | ENSG00000103310 | 0.2254160457158354 | [142] | [112,176,174,153] | 4 | hSpCas9 | negative selection | 9527306 | 21211371 | 21211394 | 16 | + | 27260156 | TC32 | viability | GAAGAGAGAAATCGACCTGTAGG | ZP2 | ENSG00000103310 | -0.30917338177492015 | [425] | [260,212,441,434] | -5 | hSpCas9 | negative selection | 9527307 | 21206922 | 21206945 | 16 | + | 27260156 | TC32 | viability | CATGACAGCTCCGTGTCTTAAGG | ZP2 | ENSG00000103310 | 0.05888398143523732 | [280] | [179,183,378,414] | 1 | hSpCas9 | negative selection | 9527308 | 21206877 | 21206900 | 16 | - | 27869803 | HPAFII | viability after 27 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | 0.6120706871124666 | [366] | [247,333,NaN] | 5 | hSpCas9 | negative selection | 9556075 | 21209701 | 21209724 | 16 | + | 27869803 | HPAFII | viability after 27 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.7516958388979124 | [418] | [173,534,NaN] | 6 | hSpCas9 | negative selection | 9556076 | 21211525 | 21211548 | 16 | - | 27869803 | HPAFII | viability after 27 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -1.1628927569143381 | [337] | [62,92,NaN] | -7 | hSpCas9 | negative selection | 9556077 | 21206877 | 21206900 | 16 | - | 27869803 | HPAFII | viability after 15 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | 0.20318496252279394 | [366] | [569,381,NaN] | 2 | hSpCas9 | negative selection | 9638524 | 21209701 | 21209724 | 16 | + | 27869803 | HPAFII | viability after 15 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | -0.24044461334301304 | [418] | [366,389,NaN] | -3 | hSpCas9 | negative selection | 9638525 | 21211525 | 21211548 | 16 | - | 27869803 | HPAFII | viability after 15 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -1.3271084486901488 | [337] | [137,148,NaN] | -8 | hSpCas9 | negative selection | 9638526 | 21206877 | 21206900 | 16 | - | 27869803 | ASPC1 | viability after 36 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | 0.7957182527154618 | [699] | [559,231,476] | 7 | hSpCas9 | negative selection | 9720973 | 21209701 | 21209724 | 16 | + | 27869803 | ASPC1 | viability after 36 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.7433451964755098 | [824] | [948,226,351] | 7 | hSpCas9 | negative selection | 9720974 | 21211525 | 21211548 | 16 | - | 27869803 | ASPC1 | viability after 36 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | 0.6629846324901262 | [642] | [170,236,574] | 6 | hSpCas9 | negative selection | 9720975 | 21206877 | 21206900 | 16 | - | 27869803 | PATU8988S | viability after 35 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | -0.06175228575215777 | [638] | [278,213,NaN] | 0 | hSpCas9 | negative selection | 9803422 | 21209701 | 21209724 | 16 | + | 27869803 | PATU8988S | viability after 35 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.5036772606397205 | [674] | [360,409,NaN] | 5 | hSpCas9 | negative selection | 9803423 | 21211525 | 21211548 | 16 | - | 27869803 | PATU8988S | viability after 35 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -1.3478893419372515 | [625] | [120,76,NaN] | -8 | hSpCas9 | negative selection | 9803424 | 21206877 | 21206900 | 16 | - | 27869803 | PATU8988S | viability after 31 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | -0.2612317633254266 | [638] | [194,234,NaN] | -3 | hSpCas9 | negative selection | 9885871 | 21209701 | 21209724 | 16 | + | 27869803 | PATU8988S | viability after 31 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.8359016409807898 | [674] | [424,550,NaN] | 8 | hSpCas9 | negative selection | 9885872 | 21211525 | 21211548 | 16 | - | 27869803 | PATU8988S | viability after 31 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -1.217719199414409 | [625] | [127,80,NaN] | -8 | hSpCas9 | negative selection | 9885873 | 21206877 | 21206900 | 16 | - | 27869803 | HPAFII | viability after 35 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | 1.4189346372006917 | [366] | [421,580,NaN] | 8 | hSpCas9 | negative selection | 9968320 | 21209701 | 21209724 | 16 | + | 27869803 | HPAFII | viability after 35 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.9341720991220172 | [418] | [84,765,NaN] | 6 | hSpCas9 | negative selection | 9968321 | 21211525 | 21211548 | 16 | - | 27869803 | HPAFII | viability after 35 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -0.9001960350474275 | [337] | [46,141,NaN] | -5 | hSpCas9 | negative selection | 9968322 | 21206877 | 21206900 | 16 | - | 27869803 | HPAFII | viability after 31 days | TGCAAGTAGAAGAGACCCAGGGG | ZP2 | ENSG00000103310 | 1.0680021094443364 | [366] | [315,557,NaN] | 7 | hSpCas9 | negative selection | 10050769 | 21209701 | 21209724 | 16 | + | 27869803 | HPAFII | viability after 31 days | TTCGGCATGTCGAGACCAAGAGG | ZP2 | ENSG00000103310 | 0.7759728817770294 | [418] | [193,629,NaN] | 5 | hSpCas9 | negative selection | 10050770 | 21211525 | 21211548 | 16 | - | 27869803 | HPAFII | viability after 31 days | ATGGCGTGCAGGCAGAGAGGAGG | ZP2 | ENSG00000103310 | -1.511451199722893 | [337] | [44,89,NaN] | -7 | hSpCas9 | negative selection | 10050771 | 21210125 | 21210148 | 16 | - | 28162770 | P31FUJ | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | -0.2055807356793542 | [104] | [106] | -2 | hSpCas9 | negative selection | 10273484 | 21210125 | 21210148 | 16 | - | 28162770 | TF1 | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | NaN | [NaN] | [84] | 1 | hSpCas9 | negative selection | 10442850 | 21210125 | 21210148 | 16 | - | 28162770 | SKM1 | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | -0.0038400210078186614 | [37] | [66] | 0 | hSpCas9 | negative selection | 10612216 | 21210125 | 21210148 | 16 | - | 28162770 | SKM1 | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | -0.0038400210078186614 | [37] | [66] | 0 | hSpCas9 | negative selection | 10781582 | 21210125 | 21210148 | 16 | - | 28162770 | PL21 | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | -0.0916265098877897 | [141] | [57] | 0 | hSpCas9 | negative selection | 10950948 | 21210125 | 21210148 | 16 | - | 28162770 | P31FUJ | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | -0.2055807356793542 | [104] | [106] | -2 | hSpCas9 | negative selection | 11120314 | 21210125 | 21210148 | 16 | - | 28162770 | OCIAML5 | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | 0.6031280548868294 | [61] | [169] | 5 | hSpCas9 | negative selection | 11289680 | 21210125 | 21210148 | 16 | - | 28162770 | EOL1 | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | 0.520548543744139 | [216] | [163] | 5 | hSpCas9 | negative selection | 11459046 | 21210125 | 21210148 | 16 | - | 28162770 | MOLM13 | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | 0.16421299121343902 | [215] | [174] | 1 | hSpCas9 | negative selection | 11628412 | 21210125 | 21210148 | 16 | - | 28162770 | HEL | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | 0.16630078805736986 | [191] | [137] | 1 | hSpCas9 | negative selection | 11797778 | 21210125 | 21210148 | 16 | - | 28162770 | MV411 | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | -0.9130271214104708 | [151] | [67] | -6 | hSpCas9 | negative selection | 11967144 | 21210125 | 21210148 | 16 | - | 28162770 | MONOMAC1 | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | -0.5267422925386354 | [92] | [73] | -4 | hSpCas9 | negative selection | 12136510 | 21210125 | 21210148 | 16 | - | 28162770 | OCIAML2 | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | 0.1060174072669913 | [28] | [172] | 1 | hSpCas9 | negative selection | 12305876 | 21210125 | 21210148 | 16 | - | 28162770 | OCIAML3 | viability | GCAGTCCTGGCACCAAGAAATGG | ZP2 | ENSG00000103310 | 0.877298078601426 | [32] | [182] | 7 | hSpCas9 | negative selection | 12475242 |