Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:790
• Symbol:cad
• Description:carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

DataSource: http://genomecrispr.dkfz.de/#!/results/cad

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
27225875	27225898	2	+	26472758	Jiyoye	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-2.182403747285653	[312]	[51]	-8	hSpCas9	negative selection	22657
27225820	27225843	2	-	26472758	Jiyoye	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-1.2084839164381993	[189]	[61]	-7	hSpCas9	negative selection	22658
27239211	27239234	2	+	26472758	Jiyoye	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-3.170253446529875	[381]	[31]	-9	hSpCas9	negative selection	22659
27240279	27240302	2	-	26472758	Jiyoye	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-1.8823312356891115	[87]	[17]	-8	hSpCas9	negative selection	22660
27221298	27221321	2	-	26472758	Jiyoye	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-1.3687843442761964	[249]	[72]	-7	hSpCas9	negative selection	22661
27222206	27222229	2	+	26472758	Jiyoye	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-0.7010775091461499	[165]	[76]	-5	hSpCas9	negative selection	22662
27222281	27222304	2	-	26472758	Jiyoye	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-0.2275401544123823	[58]	[37]	-2	hSpCas9	negative selection	22663
27222608	27222631	2	+	26472758	Jiyoye	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-1.914752713381489	[164]	[32]	-8	hSpCas9	negative selection	22664
27224803	27224826	2	+	26472758	Jiyoye	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-1.5053617772437873	[127]	[33]	-7	hSpCas9	negative selection	22665
27225743	27225766	2	+	26472758	Jiyoye	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-3.2157549694143035	[307]	[24]	-9	hSpCas9	negative selection	22666
27225875	27225898	2	+	26472758	KBM7	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-2.0630447793651205	[775,527]	[28,110]	-8	hSpCas9	negative selection	213775
27225820	27225843	2	-	26472758	KBM7	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-4.103914283457618	[683,658]	[19,16]	-9	hSpCas9	negative selection	213776
27239211	27239234	2	+	26472758	KBM7	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-3.936003624744824	[545,452]	[28,2]	-9	hSpCas9	negative selection	213777
27240279	27240302	2	-	26472758	KBM7	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-2.0188179367159527	[230,180]	[28,18]	-8	hSpCas9	negative selection	213778
27221298	27221321	2	-	26472758	KBM7	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-1.4613833247100594	[1523,1174]	[322,143]	-7	hSpCas9	negative selection	213779
27222206	27222229	2	+	26472758	KBM7	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-1.8293936629974121	[1255,664]	[119,126]	-8	hSpCas9	negative selection	213780
27222281	27222304	2	-	26472758	KBM7	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-1.7885462420387084	[526,412]	[25,96]	-8	hSpCas9	negative selection	213781
27222608	27222631	2	+	26472758	KBM7	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-3.683552361616214	[626,607]	[9,33]	-9	hSpCas9	negative selection	213782
27224803	27224826	2	+	26472758	KBM7	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-2.474814037322486	[993,553]	[84,44]	-9	hSpCas9	negative selection	213783
27225743	27225766	2	+	26472758	KBM7	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-2.640720591689139	[1245,892]	[85,73]	-9	hSpCas9	negative selection	213784
27225875	27225898	2	+	26472758	Raji	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-0.7406133711813505	[395]	[54]	-5	hSpCas9	negative selection	404893
27225820	27225843	2	-	26472758	Raji	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-0.4196980492670568	[512]	[88]	-3	hSpCas9	negative selection	404894
27239211	27239234	2	+	26472758	Raji	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-1.262984914571516	[423]	[40]	-7	hSpCas9	negative selection	404895
27240279	27240302	2	-	26472758	Raji	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-1.9630057925177986	[83]	[4]	-8	hSpCas9	negative selection	404896
27221298	27221321	2	-	26472758	Raji	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	0.0766212816029126	[710]	[173]	0	hSpCas9	negative selection	404897
27222206	27222229	2	+	26472758	Raji	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-0.5329060393809328	[504]	[80]	-4	hSpCas9	negative selection	404898
27222281	27222304	2	-	26472758	Raji	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-0.1772314010457071	[228]	[46]	-1	hSpCas9	negative selection	404899
27222608	27222631	2	+	26472758	Raji	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	0.2403223671917278	[258]	[70]	2	hSpCas9	negative selection	404900
27224803	27224826	2	+	26472758	Raji	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	0.2912227159406544	[492]	[139]	2	hSpCas9	negative selection	404901
27225743	27225766	2	+	26472758	Raji	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-0.7773539179963684	[516]	[69]	-5	hSpCas9	negative selection	404902
27225875	27225898	2	+	26472758	K562	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-3.8062073454035215	[695]	[41]	-9	hSpCas9	negative selection	596011
27225820	27225843	2	-	26472758	K562	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-5.9053283918382355	[567]	[7]	-9	hSpCas9	negative selection	596012
27239211	27239234	2	+	26472758	K562	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-3.0560651154818523	[600]	[60]	-8	hSpCas9	negative selection	596013
27240279	27240302	2	-	26472758	K562	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-6.333010100369302	[190]	[1]	-9	hSpCas9	negative selection	596014
27221298	27221321	2	-	26472758	K562	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-1.5260194431177156	[1060]	[310]	-6	hSpCas9	negative selection	596015
27222206	27222229	2	+	26472758	K562	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-2.0734776132018653	[1071]	[214]	-7	hSpCas9	negative selection	596016
27222281	27222304	2	-	26472758	K562	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-1.6070587476234652	[331]	[91]	-7	hSpCas9	negative selection	596017
27222608	27222631	2	+	26472758	K562	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-3.7980733544476317	[378]	[22]	-9	hSpCas9	negative selection	596018
27224803	27224826	2	+	26472758	K562	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-3.8777398548451383	[504]	[28]	-9	hSpCas9	negative selection	596019
27225743	27225766	2	+	26472758	K562	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-4.749688704410352	[732]	[22]	-9	hSpCas9	negative selection	596020
27217555	27217578	2	+	26627737	DLD1	viability	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-1.5034209351896135	[459]	[42,49,57]	-8	hSpCas9	negative selection	811517
27221335	27221358	2	-	26627737	DLD1	viability	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.286913185149232	[563]	[224,199,218]	3	hSpCas9	negative selection	811518
27222213	27222236	2	+	26627737	DLD1	viability	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	-0.7371876682016616	[487]	[55,144,77]	-6	hSpCas9	negative selection	811519
27222548	27222571	2	-	26627737	DLD1	viability	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-3.403079158061456	[234]	[11,3,4]	-9	hSpCas9	negative selection	811520
27222877	27222900	2	+	26627737	DLD1	viability	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	-0.5557231294115967	[352]	[61,83,78]	-5	hSpCas9	negative selection	811521
27223738	27223761	2	-	26627737	DLD1	viability	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-1.5506106642660322	[625]	[34,30,123]	-8	hSpCas9	negative selection	811522
27217555	27217578	2	+	26627737	GBM cells	viability after 5 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	0.15956562940848532	[201]	[136,104]	2	hSpCas9	negative selection	893832
27221335	27221358	2	-	26627737	GBM cells	viability after 5 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.3706315687536467	[286]	[152,244]	5	hSpCas9	negative selection	893833
27222213	27222236	2	+	26627737	GBM cells	viability after 5 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	0.32400503882845216	[285]	[169,213]	5	hSpCas9	negative selection	893834
27222548	27222571	2	-	26627737	GBM cells	viability after 5 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-0.600187889181633	[105]	[32,41]	-7	hSpCas9	negative selection	893835
27222877	27222900	2	+	26627737	GBM cells	viability after 5 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.232814611439124	[191]	[109,131]	3	hSpCas9	negative selection	893836
27223738	27223761	2	-	26627737	GBM cells	viability after 5 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-0.0378503238219533	[490]	[250,261]	0	hSpCas9	negative selection	893837
27217555	27217578	2	+	26627737	GBM cells	viability after 13 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	0.31080837606607914	[201]	[173,104]	4	hSpCas9	negative selection	976147
27221335	27221358	2	-	26627737	GBM cells	viability after 13 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	1.0406152783576905	[286]	[289,344]	9	hSpCas9	negative selection	976148
27222213	27222236	2	+	26627737	GBM cells	viability after 13 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	0.8707831374498034	[285]	[296,272]	8	hSpCas9	negative selection	976149
27222548	27222571	2	-	26627737	GBM cells	viability after 13 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-0.7250458138953029	[105]	[36,32]	-7	hSpCas9	negative selection	976150
27222877	27222900	2	+	26627737	GBM cells	viability after 13 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.5585442243635024	[191]	[180,130]	7	hSpCas9	negative selection	976151
27223738	27223761	2	-	26627737	GBM cells	viability after 13 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	0.28972187058586674	[490]	[398,265]	3	hSpCas9	negative selection	976152
27217555	27217578	2	+	26627737	GBM cells	viability after 21 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	0.7816325921003411	[201]	[184,191]	7	hSpCas9	negative selection	1058462
27221335	27221358	2	-	26627737	GBM cells	viability after 21 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.8926351643995689	[286]	[289,288]	8	hSpCas9	negative selection	1058463
27222213	27222236	2	+	26627737	GBM cells	viability after 21 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	0.515355369243482	[285]	[219,223]	5	hSpCas9	negative selection	1058464
27222548	27222571	2	-	26627737	GBM cells	viability after 21 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-0.02043267545223193	[105]	[61,51]	0	hSpCas9	negative selection	1058465
27222877	27222900	2	+	26627737	GBM cells	viability after 21 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.6955810124267934	[191]	[193,145]	7	hSpCas9	negative selection	1058466
27223738	27223761	2	-	26627737	GBM cells	viability after 21 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	0.26648419765731923	[490]	[323,317]	2	hSpCas9	negative selection	1058467
27217555	27217578	2	+	26627737	RPE1	viability after 9 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	0.8054858380704253	[593]	[207,475]	5	hSpCas9	negative selection	1140777
27221335	27221358	2	-	26627737	RPE1	viability after 9 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	2.31007917416256	[294]	[581,297]	9	hSpCas9	negative selection	1140778
27222213	27222236	2	+	26627737	RPE1	viability after 9 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	-0.8663702238516726	[1318]	[229,221]	-6	hSpCas9	negative selection	1140779
27222548	27222571	2	-	26627737	RPE1	viability after 9 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	4.475611927323036	[16]	[72,176]	9	hSpCas9	negative selection	1140780
27222877	27222900	2	+	26627737	RPE1	viability after 9 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.21403803649569195	[593]	[254,164]	1	hSpCas9	negative selection	1140781
27223738	27223761	2	-	26627737	RPE1	viability after 9 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	0.7043467296579129	[1419]	[564,929]	4	hSpCas9	negative selection	1140782
27217555	27217578	2	+	26627737	RPE1	viability after 12 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	0.9075850205964653	[593]	[209,393]	5	hSpCas9	negative selection	1223092
27221335	27221358	2	-	26627737	RPE1	viability after 12 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	2.346994324205948	[294]	[478,322]	9	hSpCas9	negative selection	1223093
27222213	27222236	2	+	26627737	RPE1	viability after 12 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	-0.39444075128391076	[1318]	[391,139]	-3	hSpCas9	negative selection	1223094
27222548	27222571	2	-	26627737	RPE1	viability after 12 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	4.907582995771266	[16]	[71,205]	9	hSpCas9	negative selection	1223095
27222877	27222900	2	+	26627737	RPE1	viability after 12 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.3428577706793199	[593]	[249,151]	2	hSpCas9	negative selection	1223096
27223738	27223761	2	-	26627737	RPE1	viability after 12 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	0.758613693525368	[1419]	[439,862]	5	hSpCas9	negative selection	1223097
27217555	27217578	2	+	26627737	RPE1	viability after 15 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	1.4442726819963265	[593]	[414,497]	7	hSpCas9	negative selection	1305407
27221335	27221358	2	-	26627737	RPE1	viability after 15 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	1.6462962798788012	[294]	[276,245]	8	hSpCas9	negative selection	1305408
27222213	27222236	2	+	26627737	RPE1	viability after 15 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	-0.44094011719423404	[1318]	[310,239]	-3	hSpCas9	negative selection	1305409
27222548	27222571	2	-	26627737	RPE1	viability after 15 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	5.038851583789219	[16]	[96,216]	9	hSpCas9	negative selection	1305410
27222877	27222900	2	+	26627737	RPE1	viability after 15 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.10803283737398706	[593]	[231,131]	0	hSpCas9	negative selection	1305411
27223738	27223761	2	-	26627737	RPE1	viability after 15 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	0.42361548450381625	[1419]	[466,607]	2	hSpCas9	negative selection	1305412
27217555	27217578	2	+	26627737	RPE1	viability after 18 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	0.9683794211904145	[593]	[288,339]	6	hSpCas9	negative selection	1387722
27221335	27221358	2	-	26627737	RPE1	viability after 18 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	2.332060980987782	[294]	[425,373]	9	hSpCas9	negative selection	1387723
27222213	27222236	2	+	26627737	RPE1	viability after 18 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	-1.1314540375235735	[1318]	[190,131]	-6	hSpCas9	negative selection	1387724
27222548	27222571	2	-	26627737	RPE1	viability after 18 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	5.211355014193906	[16]	[139,201]	9	hSpCas9	negative selection	1387725
27222877	27222900	2	+	26627737	RPE1	viability after 18 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	-0.004732656521203915	[593]	[196,119]	0	hSpCas9	negative selection	1387726
27223738	27223761	2	-	26627737	RPE1	viability after 18 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	0.7737616339189206	[1419]	[616,695]	5	hSpCas9	negative selection	1387727
27217555	27217578	2	+	26627737	HeLa	viability after 8 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-1.3498050541932343	[281]	[20,106,12]	-8	hSpCas9	negative selection	1470037
27221335	27221358	2	-	26627737	HeLa	viability after 8 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.6867309273444216	[366]	[285,374,125]	6	hSpCas9	negative selection	1470038
27222213	27222236	2	+	26627737	HeLa	viability after 8 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	1.4121255802776305	[286]	[336,460,208]	8	hSpCas9	negative selection	1470039
27222548	27222571	2	-	26627737	HeLa	viability after 8 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-2.234530896765413	[194]	[61,1,0]	-9	hSpCas9	negative selection	1470040
27222877	27222900	2	+	26627737	HeLa	viability after 8 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.892878956948713	[199]	[195,158,138]	7	hSpCas9	negative selection	1470041
27223738	27223761	2	-	26627737	HeLa	viability after 8 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-0.9496291180750649	[754]	[167,188,153]	-7	hSpCas9	negative selection	1470042
27217555	27217578	2	+	26627737	HeLa	viability after 12 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-0.951909441082985	[281]	[69,50,60]	-7	hSpCas9	negative selection	1552352
27221335	27221358	2	-	26627737	HeLa	viability after 12 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.6535322136281777	[366]	[124,185,406]	5	hSpCas9	negative selection	1552353
27222213	27222236	2	+	26627737	HeLa	viability after 12 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	1.1540848909011105	[286]	[307,302,177]	8	hSpCas9	negative selection	1552354
27222548	27222571	2	-	26627737	HeLa	viability after 12 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-3.369934361591341	[194]	[0,18,1]	-9	hSpCas9	negative selection	1552355
27222877	27222900	2	+	26627737	HeLa	viability after 12 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.6275968457608714	[199]	[89,155,132]	5	hSpCas9	negative selection	1552356
27223738	27223761	2	-	26627737	HeLa	viability after 12 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-2.0694616963323686	[754]	[138,44,43]	-9	hSpCas9	negative selection	1552357
27217555	27217578	2	+	26627737	HeLa	viability after 15 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-0.11710445045980356	[281]	[66,157,91]	-1	hSpCas9	negative selection	1634667
27221335	27221358	2	-	26627737	HeLa	viability after 15 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	-0.6542311718882672	[366]	[20,178,84]	-5	hSpCas9	negative selection	1634668
27222213	27222236	2	+	26627737	HeLa	viability after 15 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	1.6018318596696843	[286]	[295,397,371]	9	hSpCas9	negative selection	1634669
27222548	27222571	2	-	26627737	HeLa	viability after 15 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-2.884569304580719	[194]	[0,0,31]	-9	hSpCas9	negative selection	1634670
27222877	27222900	2	+	26627737	HeLa	viability after 15 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.8775547935079375	[199]	[158,159,127]	6	hSpCas9	negative selection	1634671
27223738	27223761	2	-	26627737	HeLa	viability after 15 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-2.3038408473408207	[754]	[112,23,47]	-9	hSpCas9	negative selection	1634672
27217555	27217578	2	+	26627737	HeLa	viability after 18 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-0.08671777897168131	[281]	[41,139,91]	0	hSpCas9	negative selection	1716982
27221335	27221358	2	-	26627737	HeLa	viability after 18 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	-0.6625644037226391	[366]	[13,146,84]	-5	hSpCas9	negative selection	1716983
27222213	27222236	2	+	26627737	HeLa	viability after 18 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	1.5971190391861505	[286]	[199,324,371]	8	hSpCas9	negative selection	1716984
27222548	27222571	2	-	26627737	HeLa	viability after 18 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-2.8527289450590687	[194]	[0,0,31]	-9	hSpCas9	negative selection	1716985
27222877	27222900	2	+	26627737	HeLa	viability after 18 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.9105373285777859	[199]	[108,137,127]	7	hSpCas9	negative selection	1716986
27223738	27223761	2	-	26627737	HeLa	viability after 18 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-2.286283448005313	[754]	[77,18,47]	-9	hSpCas9	negative selection	1716987
27217555	27217578	2	+	26627737	HCT116	viability after 6 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	0.3061855575912592	[967]	[318,115]	1	hSpCas9	negative selection	1799297
27221335	27221358	2	-	26627737	HCT116	viability after 6 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	1.5635227120727972	[699]	[196,395]	7	hSpCas9	negative selection	1799298
27222213	27222236	2	+	26627737	HCT116	viability after 6 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	-0.7532482061747572	[563]	[40,58]	-4	hSpCas9	negative selection	1799299
27222548	27222571	2	-	26627737	HCT116	viability after 6 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-0.3734255197085251	[329]	[21,49]	-2	hSpCas9	negative selection	1799300
27222877	27222900	2	+	26627737	HCT116	viability after 6 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	1.2814780387154867	[428]	[103,196]	6	hSpCas9	negative selection	1799301
27223738	27223761	2	-	26627737	HCT116	viability after 6 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-1.073048636588693	[787]	[103,33]	-6	hSpCas9	negative selection	1799302
27217555	27217578	2	+	26627737	HCT116	viability after 8 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-1.3511827914465746	[350]	[84,99,42]	-9	hSpCas9	negative selection	1881612
27221335	27221358	2	-	26627737	HCT116	viability after 8 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.3361919025717338	[269]	[128,211,220]	3	hSpCas9	negative selection	1881613
27222213	27222236	2	+	26627737	HCT116	viability after 8 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	2.003168453868213	[93]	[61,323,233]	9	hSpCas9	negative selection	1881614
27222548	27222571	2	-	26627737	HCT116	viability after 8 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-0.3294304841020659	[113]	[44,63,40]	-4	hSpCas9	negative selection	1881615
27222877	27222900	2	+	26627737	HCT116	viability after 8 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	1.6903492626694254	[79]	[174,77,173]	9	hSpCas9	negative selection	1881616
27223738	27223761	2	-	26627737	HCT116	viability after 8 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-2.181638336559971	[466]	[14,62,90]	-9	hSpCas9	negative selection	1881617
27217555	27217578	2	+	26627737	HCT116	viability after 9 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-2.6190824576742076	[967]	[69,19]	-9	hSpCas9	negative selection	1963927
27221335	27221358	2	-	26627737	HCT116	viability after 9 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	1.0656010616561513	[699]	[350,422]	7	hSpCas9	negative selection	1963928
27222213	27222236	2	+	26627737	HCT116	viability after 9 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	1.4287561500598769	[563]	[262,517]	8	hSpCas9	negative selection	1963929
27222548	27222571	2	-	26627737	HCT116	viability after 9 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-2.854868832960269	[329]	[19,5]	-9	hSpCas9	negative selection	1963930
27222877	27222900	2	+	26627737	HCT116	viability after 9 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	-0.2412717295310467	[428]	[154,50]	-2	hSpCas9	negative selection	1963931
27223738	27223761	2	-	26627737	HCT116	viability after 9 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-0.8367338853778601	[787]	[90,138]	-5	hSpCas9	negative selection	1963932
27217555	27217578	2	+	26627737	HCT116	viability after 12 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-4.2048040605226324	[350]	[8,5,14]	-9	hSpCas9	negative selection	2046242
27221335	27221358	2	-	26627737	HCT116	viability after 12 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.8424078853618403	[269]	[264,240,255]	7	hSpCas9	negative selection	2046243
27222213	27222236	2	+	26627737	HCT116	viability after 12 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	1.530755557175164	[93]	[106,169,154]	9	hSpCas9	negative selection	2046244
27222548	27222571	2	-	26627737	HCT116	viability after 12 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-5.130584590940727	[113]	[2,0,0]	-9	hSpCas9	negative selection	2046245
27222877	27222900	2	+	26627737	HCT116	viability after 12 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	1.5225250388143783	[79]	[132,67,158]	9	hSpCas9	negative selection	2046246
27223738	27223761	2	-	26627737	HCT116	viability after 12 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-4.261572749926194	[466]	[9,27,0]	-9	hSpCas9	negative selection	2046247
27217555	27217578	2	+	26627737	HCT116	viability after 15 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-4.047623430104126	[350]	[7,10,16]	-9	hSpCas9	negative selection	2128557
27221335	27221358	2	-	26627737	HCT116	viability after 15 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.8643344380181854	[269]	[317,233,298]	7	hSpCas9	negative selection	2128558
27222213	27222236	2	+	26627737	HCT116	viability after 15 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	1.7225224019641399	[93]	[97,272,153]	9	hSpCas9	negative selection	2128559
27222548	27222571	2	-	26627737	HCT116	viability after 15 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-3.0347795075011605	[113]	[23,0,0]	-9	hSpCas9	negative selection	2128560
27222877	27222900	2	+	26627737	HCT116	viability after 15 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	1.6524033190309866	[79]	[245,84,114]	9	hSpCas9	negative selection	2128561
27223738	27223761	2	-	26627737	HCT116	viability after 15 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-3.732309122147952	[466]	[47,1,13]	-9	hSpCas9	negative selection	2128562
27217555	27217578	2	+	26627737	HCT116	viability after 18 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-4.427905128170489	[350]	[8,12,0]	-9	hSpCas9	negative selection	2210872
27221335	27221358	2	-	26627737	HCT116	viability after 18 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.2702619897989334	[269]	[141,148,182]	2	hSpCas9	negative selection	2210873
27222213	27222236	2	+	26627737	HCT116	viability after 18 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	1.0852296222507118	[93]	[55,80,155]	8	hSpCas9	negative selection	2210874
27222548	27222571	2	-	26627737	HCT116	viability after 18 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-3.1119940784368803	[113]	[4,7,5]	-9	hSpCas9	negative selection	2210875
27222877	27222900	2	+	26627737	HCT116	viability after 18 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.9180975931506392	[79]	[104,44,70]	7	hSpCas9	negative selection	2210876
27223738	27223761	2	-	26627737	HCT116	viability after 18 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-4.098870199916704	[466]	[32,0,5]	-9	hSpCas9	negative selection	2210877
27217548	27217571	2	+	24336569	HL60	viability	TCCCATGGCGGCCCTAGTGTTGG	CAD	ENSG00000084774	-3.9785069102810673	[364]	[48]	-9	hSpCas9	negative selection	2254133
27217555	27217578	2	+	24336569	HL60	viability	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-2.386010117288022	[824]	[333]	-9	hSpCas9	negative selection	2254134
27217560	27217583	2	-	24336569	HL60	viability	CCGACCCGTCCTCCAACACTAGG	CAD	ENSG00000084774	-1.6356643475793655	[695]	[473]	-8	hSpCas9	negative selection	2254135
27217568	27217591	2	+	24336569	HL60	viability	TGGAGGACGGGTCGGTCCTGCGG	CAD	ENSG00000084774	1.3973155286995387	[100]	[562]	8	hSpCas9	negative selection	2254136
27217604	27217627	2	+	24336569	HL60	viability	GGGCCGCCGTGTCGACTGCCGGG	CAD	ENSG00000084774	-0.15481025019894784	[463]	[881]	-1	hSpCas9	negative selection	2254137
27217867	27217890	2	+	24336569	HL60	viability	TTTCTTGCAGTGTTTCAAACCGG	CAD	ENSG00000084774	1.870403403698006	[79]	[618]	9	hSpCas9	negative selection	2254138
27217872	27217895	2	+	24336569	HL60	viability	TGCAGTGTTTCAAACCGGCATGG	CAD	ENSG00000084774	-1.0425009450845084	[620]	[637]	-7	hSpCas9	negative selection	2254139
27217916	27217939	2	-	24336569	HL60	viability	CTGTGCCTTGTAGGAGGGATCAG	CAD	ENSG00000084774	-0.9243491249725289	[816]	[910]	-7	hSpCas9	negative selection	2254140
27217548	27217571	2	+	24336569	KBM7	viability	TCCCATGGCGGCCCTAGTGTTGG	CAD	ENSG00000084774	-10.087824132771228	[398]	[0]	-9	hSpCas9	negative selection	2321310
27217555	27217578	2	+	24336569	KBM7	viability	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-2.3892973807104894	[848]	[441]	-8	hSpCas9	negative selection	2321311
27217560	27217583	2	-	24336569	KBM7	viability	CCGACCCGTCCTCCAACACTAGG	CAD	ENSG00000084774	-2.17938308559931	[464]	[279]	-8	hSpCas9	negative selection	2321312
27217568	27217591	2	+	24336569	KBM7	viability	TGGAGGACGGGTCGGTCCTGCGG	CAD	ENSG00000084774	0.2528605215922096	[191]	[623]	2	hSpCas9	negative selection	2321313
27217604	27217627	2	+	24336569	KBM7	viability	GGGCCGCCGTGTCGACTGCCGGG	CAD	ENSG00000084774	-0.5597369544689027	[614]	[1137]	-4	hSpCas9	negative selection	2321314
27217867	27217890	2	+	24336569	KBM7	viability	TTTCTTGCAGTGTTTCAAACCGG	CAD	ENSG00000084774	-0.4696055028788815	[131]	[259]	-4	hSpCas9	negative selection	2321315
27217872	27217895	2	+	24336569	KBM7	viability	TGCAGTGTTTCAAACCGGCATGG	CAD	ENSG00000084774	-0.7471394784077903	[175]	[285]	-5	hSpCas9	negative selection	2321316
27217916	27217939	2	-	24336569	KBM7	viability	CTGTGCCTTGTAGGAGGGATCAG	CAD	ENSG00000084774	0.8503889993942986	[509]	[2507]	7	hSpCas9	negative selection	2321317
27232122	27232145	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGCTGCTAGAACAACACCGTGG	CAD	ENSG00000084774	-0.9049111225253389	[3,3]	[2,0]	-8	hSpCas9	positive selection	2975980
27224804	27224827	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	0.22614675769538217	[4,4]	[3,5]	5	hSpCas9	positive selection	2975981
27222523	27222546	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCACGGGTATTCAATACAGGGGG	CAD	ENSG00000084774	-1.471333616433477	[2,3]	[0,0]	-9	hSpCas9	positive selection	2975982
27225079	27225102	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTGGAGCTGACCAAGGCCGGGG	CAD	ENSG00000084774	-0.4700166667582829	[2,2]	[1,1]	-6	hSpCas9	positive selection	2975983
27232122	27232145	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGCTGCTAGAACAACACCGTGG	CAD	ENSG00000084774	-0.49302136432896915	[3,3]	[3,0]	-7	hSpCas9	positive selection	3043838
27224804	27224827	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	0.28896317352646994	[4,4]	[4,4]	5	hSpCas9	positive selection	3043839
27222523	27222546	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCACGGGTATTCAATACAGGGGG	CAD	ENSG00000084774	-0.8254198150552874	[2,2]	[1,0]	-9	hSpCas9	positive selection	3043840
27225079	27225102	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTGGAGCTGACCAAGGCCGGGG	CAD	ENSG00000084774	0.3768625794150866	[2,2]	[1,2]	6	hSpCas9	positive selection	3043841
27221294	27221317		+	24336571	A375	resistance to PLX after 7 days	CCACCCGCACCCTGCATGAGTGG	CAD	ENSG00000084774	0.6206083685437453	[5,4]	[9,7]	9	hSpCas9	positive selection	3160270
27221238	27221261		+	24336571	A375	resistance to PLX after 7 days	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	0.040297309140472914	[6,5]	[5,6]	1	hSpCas9	positive selection	3160271
27221238	27221261		-	24336571	A375	resistance to PLX after 7 days	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.13010423330150012	[8,11]	[7,9]	-4	hSpCas9	positive selection	3160273
27221294	27221317		+	24336571	A375	resistance to PLX after 14 days	CCACCCGCACCCTGCATGAGTGG	CAD	ENSG00000084774	2.0576571118543536	[5,3]	[10,9]	9	hSpCas9	positive selection	3218063
27221238	27221261		+	24336571	A375	resistance to PLX after 14 days	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.9903262668999171	[9,9]	[1,1]	-9	hSpCas9	positive selection	3218064
27221238	27221261		-	24336571	A375	resistance to PLX after 14 days	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.6843568346193349	[8,11]	[2,1]	-7	hSpCas9	positive selection	3218066
27221294	27221317		+	24336571	A375	viability after 7 days	CCACCCGCACCCTGCATGAGTGG	CAD	ENSG00000084774	-1.712112654966121	[20]	[5,4]	-9	hSpCas9	negative selection	3275856
27221238	27221261		+	24336571	A375	viability after 7 days	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.8463908274319212	[12]	[6,5]	-8	hSpCas9	negative selection	3275857
27221238	27221261		-	24336571	A375	viability after 7 days	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.6185011122982933	[16]	[8,11]	-7	hSpCas9	negative selection	3275859
27221294	27221317		+	24336571	A375	viability after 14 days	CCACCCGCACCCTGCATGAGTGG	CAD	ENSG00000084774	-1.869456161359755	[20]	[5,3]	-9	hSpCas9	negative selection	3333649
27221238	27221261		+	24336571	A375	viability after 14 days	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.19267834321478444	[12]	[9,9]	-2	hSpCas9	negative selection	3333650
27221238	27221261		-	24336571	A375	viability after 14 days	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.5941212986848838	[16]	[8,11]	-6	hSpCas9	negative selection	3333652
27221238	27221261	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.6712453814928309	[263,222]	[0,0]	-4	hSpCas9	positive selection	3340796
27222522	27222545	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.466005698768154	[184,237]	[0,0]	-3	hSpCas9	positive selection	3340797
27222519	27222542	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.6736411712537099	[82,108]	[0,0]	3	hSpCas9	positive selection	3340798
27217945	27217968	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-0.819489385604996	[269,269]	[0,0]	-5	hSpCas9	positive selection	3360048
27221238	27221261	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	0.16986337019549572	[135,135]	[0,0]	0	hSpCas9	positive selection	3360049
27232121	27232144	2	+	26780180	HT29	viability (Avana library 4 designs)	CAGCTGCTAGAACAACACCGTGG	CAD	ENSG00000084774	5.60049376435285	[]	[]	9	hSpCas9	negative selection	3412255
27224803	27224826	2	+	26780180	HT29	viability (Avana library 4 designs)	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	3.91411704741788	[]	[]	9	hSpCas9	negative selection	3412256
27222522	27222545	2	+	26780180	HT29	viability (Avana library 4 designs)	CCACGGGTATTCAATACAGGGGG	CAD	ENSG00000084774	3.75622814753782	[]	[]	9	hSpCas9	negative selection	3412257
27225078	27225101	2	+	26780180	HT29	viability (Avana library 4 designs)	TGTGGAGCTGACCAAGGCCGGGG	CAD	ENSG00000084774	1.88832535473965	[]	[]	7	hSpCas9	negative selection	3412258
27225078	27225101	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGGAGCTGACCAAGGCCGGGG	CAD	ENSG00000084774	-4.6415887733186	[]	[]	-5	hSpCas9	negative selection	3487629
27232121	27232144	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGCTGCTAGAACAACACCGTGG	CAD	ENSG00000084774	-15.8017437748549	[]	[]	-9	hSpCas9	negative selection	3487630
27222522	27222545	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCACGGGTATTCAATACAGGGGG	CAD	ENSG00000084774	-2.79863463223548	[]	[]	-3	hSpCas9	negative selection	3487631
27224803	27224826	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-13.6332200733177	[]	[]	-8	hSpCas9	negative selection	3487632
27222547	27222570	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTCCAAAGCAAGGATCCGAGGGG	CAD	ENSG00000084774	-12.8752733833961	[]	[]	-8	hSpCas9	negative selection	3487633
27231516	27231539	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCTCATCCACCATGCGCAGGG	CAD	ENSG00000084774	-7.70370068387852	[]	[]	-7	hSpCas9	negative selection	3487634
27225078	27225101	2	+	26780180	A375	viability (Avana lentiGuide)	TGTGGAGCTGACCAAGGCCGGGG	CAD	ENSG00000084774	12.2363218528593	[]	[]	7	hSpCas9	negative selection	3596288
27232121	27232144	2	+	26780180	A375	viability (Avana lentiGuide)	CAGCTGCTAGAACAACACCGTGG	CAD	ENSG00000084774	35.7305990142218	[]	[]	9	hSpCas9	negative selection	3596289
27222522	27222545	2	+	26780180	A375	viability (Avana lentiGuide)	CCACGGGTATTCAATACAGGGGG	CAD	ENSG00000084774	8.46803702908007	[]	[]	6	hSpCas9	negative selection	3596290
27224803	27224826	2	+	26780180	A375	viability (Avana lentiGuide)	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	22.8456053493441	[]	[]	9	hSpCas9	negative selection	3596291
27222547	27222570	2	-	26780180	A375	viability (Avana lentiGuide)	GTCCAAAGCAAGGATCCGAGGGG	CAD	ENSG00000084774	17.1220781917814	[]	[]	8	hSpCas9	negative selection	3596292
27231516	27231539	2	-	26780180	A375	viability (Avana lentiGuide)	GTTCTCATCCACCATGCGCAGGG	CAD	ENSG00000084774	15.3229875242147	[]	[]	8	hSpCas9	negative selection	3596293
27225078	27225101	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGGAGCTGACCAAGGCCGGGG	CAD	ENSG00000084774	-0.209261279899831	[4]	[3,4]	-3	hSpCas9	positive selection	3704947
27232121	27232144	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGCTGCTAGAACAACACCGTGG	CAD	ENSG00000084774	-1.5657495073531318	[4]	[0,1]	-9	hSpCas9	positive selection	3704948
27222522	27222545	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACGGGTATTCAATACAGGGGG	CAD	ENSG00000084774	-0.27724242735386523	[4]	[3,3]	-4	hSpCas9	positive selection	3704949
27224803	27224826	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-0.5040350530113875	[5]	[4,2]	-6	hSpCas9	positive selection	3704950
27222547	27222570	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCCAAAGCAAGGATCCGAGGGG	CAD	ENSG00000084774	-0.678507141716395	[5]	[3,2]	-7	hSpCas9	positive selection	3704951
27231516	27231539	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCTCATCCACCATGCGCAGGG	CAD	ENSG00000084774	-0.09847568859025516	[6]	[5,5]	-2	hSpCas9	positive selection	3704952
27225078	27225101	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGGAGCTGACCAAGGCCGGGG	CAD	ENSG00000084774	-0.43322176417461045	[5]	[3,2]	-5	hSpCas9	positive selection	3813554
27232121	27232144	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGCTGCTAGAACAACACCGTGG	CAD	ENSG00000084774	-1.1782557624937589	[5]	[2,0]	-9	hSpCas9	positive selection	3813555
27222522	27222545	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACGGGTATTCAATACAGGGGG	CAD	ENSG00000084774	-1.3487231167384777	[4]	[1,0]	-9	hSpCas9	positive selection	3813556
27224803	27224826	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-0.32989223429317893	[6]	[4,3]	-4	hSpCas9	positive selection	3813557
27222547	27222570	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCCAAAGCAAGGATCCGAGGGG	CAD	ENSG00000084774	-1.142992232202194	[5]	[0,2]	-8	hSpCas9	positive selection	3813558
27231516	27231539	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCTCATCCACCATGCGCAGGG	CAD	ENSG00000084774	-0.8754271915273331	[7]	[4,1]	-8	hSpCas9	positive selection	3813559
27222519	27222542	2	+	26780180	A375	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	1.49368943617042	[]	[]	8	hSpCas9	negative selection	3921851
27221238	27221261	2	+	26780180	A375	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	1.93444208649756	[]	[]	9	hSpCas9	negative selection	3921852
27221238	27221261	2	-	26780180	A375	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	2.27288749112827	[]	[]	9	hSpCas9	negative selection	3921853
27222522	27222545	2	-	26780180	A375	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	2.36310161177687	[]	[]	9	hSpCas9	negative selection	3921854
27217945	27217968	2	+	26780180	A375	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	2.03892833570307	[]	[]	9	hSpCas9	negative selection	3921855
27222519	27222542	2	+	26780180	HT29	viability (GeCKOv2 library)	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	2.00540340713286	[]	[]	9	hSpCas9	negative selection	4029817
27221238	27221261	2	+	26780180	HT29	viability (GeCKOv2 library)	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	1.65096794585471	[]	[]	8	hSpCas9	negative selection	4029818
27221238	27221261	2	-	26780180	HT29	viability (GeCKOv2 library)	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	2.8430687733928	[]	[]	9	hSpCas9	negative selection	4029819
27222522	27222545	2	-	26780180	HT29	viability (GeCKOv2 library)	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	2.06753606725022	[]	[]	9	hSpCas9	negative selection	4029820
27217945	27217968	2	+	26780180	HT29	viability (GeCKOv2 library)	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	2.20348967853214	[]	[]	9	hSpCas9	negative selection	4029821
27221294	27221317	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCACCCGCACCCTGCATGAGTGG	CAD	ENSG00000084774	0.18056602971979926	[3]	[1,3]	4	hSpCas9	positive selection	4188340
27221238	27221261	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.29747977001682885	[3]	[2,0]	-6	hSpCas9	positive selection	4188341
27221238	27221261	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.6040338225239631	[3]	[1,1]	-9	hSpCas9	positive selection	4188343
27221294	27221317	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCACCCGCACCCTGCATGAGTGG	CAD	ENSG00000084774	-0.2926621310418057	[4]	[3,0,2,0]	-4	hSpCas9	positive selection	4252362
27221238	27221261	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.41721441076873084	[3]	[1,0,2,0]	-6	hSpCas9	positive selection	4252363
27221238	27221261	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.9633000771081205	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4252365
27221238	27221261	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	0.09344193026745318	[3]	[2,2]	2	hSpCas9	positive selection	4260662
27222522	27222545	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.17375895907955555	[3]	[2,2]	3	hSpCas9	positive selection	4260663
27222519	27222542	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.2935475920066867	[2]	[2,0]	-6	hSpCas9	positive selection	4260664
27217945	27217968	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.06306154033830066	[3]	[3,1]	1	hSpCas9	positive selection	4324943
27221238	27221261	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.2511426265152625	[2]	[2,0]	-5	hSpCas9	positive selection	4324944
27217955	27217977	2	+	27760321	OCIAML3	viability	ATCCTCTGATCGGCAACTATGG	CAD	ENSG00000084774	-1.6388628754001693	[321,309]	[62,100]	-8	hSpCas9	negative selection	4385227
27231566	27231588	2	-	27760321	OCIAML3	viability	TACTTACCATATCGCTGACTGG	CAD	ENSG00000084774	-1.7818459020356348	[334,296]	[79,60]	-9	hSpCas9	negative selection	4385228
27232063	27232085	2	+	27760321	OCIAML3	viability	GCTCACACGCATCGACCGCTGG	CAD	ENSG00000084774	-0.9443887803745402	[1078,973]	[454,366]	-7	hSpCas9	negative selection	4385229
27232087	27232109	2	-	27760321	OCIAML3	viability	GATACGCTTCATTCGGTGCAGG	CAD	ENSG00000084774	-0.8238511247027034	[870,755]	[384,323]	-6	hSpCas9	negative selection	4385230
27222522	27222544	2	-	27760321	OCIAML3	viability	CCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.20767314708190612	[407,341]	[286,402]	2	hSpCas9	negative selection	4385231
27217955	27217977	2	+	27760321	OCIAML2	viability	ATCCTCTGATCGGCAACTATGG	CAD	ENSG00000084774	-4.525823668064985	[321,309]	[14,5]	-9	hSpCas9	negative selection	4468690
27231566	27231588	2	-	27760321	OCIAML2	viability	TACTTACCATATCGCTGACTGG	CAD	ENSG00000084774	-1.590099774582563	[334,296]	[76,94]	-8	hSpCas9	negative selection	4468691
27232063	27232085	2	+	27760321	OCIAML2	viability	GCTCACACGCATCGACCGCTGG	CAD	ENSG00000084774	-0.9792360868317733	[1078,973]	[340,525]	-7	hSpCas9	negative selection	4468692
27232087	27232109	2	-	27760321	OCIAML2	viability	GATACGCTTCATTCGGTGCAGG	CAD	ENSG00000084774	-1.1658965104884	[870,755]	[251,345]	-8	hSpCas9	negative selection	4468693
27222522	27222544	2	-	27760321	OCIAML2	viability	CCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.6921427268769162	[407,341]	[183,190]	-6	hSpCas9	negative selection	4468694
27217955	27217977	2	+	27760321	MV411	viability	ATCCTCTGATCGGCAACTATGG	CAD	ENSG00000084774	-2.529835159057733	[321,309]	[0,88]	-9	hSpCas9	negative selection	4552153
27231566	27231588	2	-	27760321	MV411	viability	TACTTACCATATCGCTGACTGG	CAD	ENSG00000084774	-2.5901794952041564	[334,296]	[0,84]	-9	hSpCas9	negative selection	4552154
27232063	27232085	2	+	27760321	MV411	viability	GCTCACACGCATCGACCGCTGG	CAD	ENSG00000084774	-0.2794320861287062	[1078,973]	[557,556]	-2	hSpCas9	negative selection	4552155
27232087	27232109	2	-	27760321	MV411	viability	GATACGCTTCATTCGGTGCAGG	CAD	ENSG00000084774	-1.0690349412882354	[870,755]	[289,202]	-6	hSpCas9	negative selection	4552156
27222522	27222544	2	-	27760321	MV411	viability	CCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.1437333055191983	[407,341]	[119,377]	-1	hSpCas9	negative selection	4552157
27217955	27217977	2	+	27760321	HL60	viability	ATCCTCTGATCGGCAACTATGG	CAD	ENSG00000084774	-0.888370600269678	[321,309]	[145,132]	-7	hSpCas9	negative selection	4635616
27231566	27231588	2	-	27760321	HL60	viability	TACTTACCATATCGCTGACTGG	CAD	ENSG00000084774	-0.8763862926661163	[334,296]	[152,126]	-7	hSpCas9	negative selection	4635617
27232063	27232085	2	+	27760321	HL60	viability	GCTCACACGCATCGACCGCTGG	CAD	ENSG00000084774	-0.9259192761130368	[1078,973]	[372,512]	-7	hSpCas9	negative selection	4635618
27232087	27232109	2	-	27760321	HL60	viability	GATACGCTTCATTCGGTGCAGG	CAD	ENSG00000084774	-1.1027120463541467	[870,755]	[263,355]	-8	hSpCas9	negative selection	4635619
27222522	27222544	2	-	27760321	HL60	viability	CCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-1.2355265120550145	[407,341]	[181,73]	-8	hSpCas9	negative selection	4635620
27217955	27217977	2	+	27760321	HT1080	viability	ATCCTCTGATCGGCAACTATGG	CAD	ENSG00000084774	0.4535760490796223	[309,241]	[130,171]	2	hSpCas9	negative selection	4719079
27231566	27231588	2	-	27760321	HT1080	viability	TACTTACCATATCGCTGACTGG	CAD	ENSG00000084774	2.948140976635457	[296,231]	[501,1153]	9	hSpCas9	negative selection	4719080
27232063	27232085	2	+	27760321	HT1080	viability	GCTCACACGCATCGACCGCTGG	CAD	ENSG00000084774	0.09535790778217712	[973,759]	[336,403]	0	hSpCas9	negative selection	4719081
27232087	27232109	2	-	27760321	HT1080	viability	GATACGCTTCATTCGGTGCAGG	CAD	ENSG00000084774	0.8764761539780772	[755,589]	[759,198]	5	hSpCas9	negative selection	4719082
27222522	27222544	2	-	27760321	HT1080	viability	CCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.5630752914573435	[341,266]	[88,277]	3	hSpCas9	negative selection	4719083
27217955	27217977	2	+	27760321	HT29	viability after 7 days	ATCCTCTGATCGGCAACTATGG	CAD	ENSG00000084774	-0.3566264804236841	[309,241]	[175,375,264]	-5	hSpCas9	negative selection	4802542
27231566	27231588	2	-	27760321	HT29	viability after 7 days	TACTTACCATATCGCTGACTGG	CAD	ENSG00000084774	-0.5498908893985083	[296,231]	[116,389,174]	-7	hSpCas9	negative selection	4802543
27232063	27232085	2	+	27760321	HT29	viability after 7 days	GCTCACACGCATCGACCGCTGG	CAD	ENSG00000084774	0.3523498526636115	[973,759]	[1279,1583,1383]	5	hSpCas9	negative selection	4802544
27232087	27232109	2	-	27760321	HT29	viability after 7 days	GATACGCTTCATTCGGTGCAGG	CAD	ENSG00000084774	-0.25824576099212193	[755,589]	[757,715,700]	-4	hSpCas9	negative selection	4802545
27222522	27222544	2	-	27760321	HT29	viability after 7 days	CCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.9346734782285437	[341,266]	[945,763,567]	9	hSpCas9	negative selection	4802546
27217955	27217977	2	+	27760321	HT29	viability after 25 days	ATCCTCTGATCGGCAACTATGG	CAD	ENSG00000084774	-1.6116635329263505	[309,241]	[114,139,47]	-7	hSpCas9	negative selection	4886005
27231566	27231588	2	-	27760321	HT29	viability after 25 days	TACTTACCATATCGCTGACTGG	CAD	ENSG00000084774	-1.4840572470884192	[296,231]	[80,142,100]	-7	hSpCas9	negative selection	4886006
27232063	27232085	2	+	27760321	HT29	viability after 25 days	GCTCACACGCATCGACCGCTGG	CAD	ENSG00000084774	-0.5264870706787197	[973,759]	[576,636,874]	-5	hSpCas9	negative selection	4886007
27232087	27232109	2	-	27760321	HT29	viability after 25 days	GATACGCTTCATTCGGTGCAGG	CAD	ENSG00000084774	-0.7504106305379676	[755,589]	[468,289,628]	-6	hSpCas9	negative selection	4886008
27222522	27222544	2	-	27760321	HT29	viability after 25 days	CCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.14869786103924432	[341,266]	[436,205,524]	1	hSpCas9	negative selection	4886009
27217955	27217977	2	+	27760321	HT29	viability after 22 days	ATCCTCTGATCGGCAACTATGG	CAD	ENSG00000084774	-0.6438314214167935	[309,241]	[137,210,265]	-5	hSpCas9	negative selection	4969468
27231566	27231588	2	-	27760321	HT29	viability after 22 days	TACTTACCATATCGCTGACTGG	CAD	ENSG00000084774	-0.9784291719105931	[296,231]	[267,95,97]	-6	hSpCas9	negative selection	4969469
27232063	27232085	2	+	27760321	HT29	viability after 22 days	GCTCACACGCATCGACCGCTGG	CAD	ENSG00000084774	-0.6288789843528705	[973,759]	[666,620,655]	-5	hSpCas9	negative selection	4969470
27232087	27232109	2	-	27760321	HT29	viability after 22 days	GATACGCTTCATTCGGTGCAGG	CAD	ENSG00000084774	-0.8022056616650981	[755,589]	[480,363,492]	-6	hSpCas9	negative selection	4969471
27222522	27222544	2	-	27760321	HT29	viability after 22 days	CCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.2950323391965592	[341,266]	[360,358,578]	3	hSpCas9	negative selection	4969472
27217955	27217977	2	+	27760321	HT29	viability after 19 days	ATCCTCTGATCGGCAACTATGG	CAD	ENSG00000084774	-1.0975211461546484	[309,241]	[181,141,122]	-6	hSpCas9	negative selection	5052931
27231566	27231588	2	-	27760321	HT29	viability after 19 days	TACTTACCATATCGCTGACTGG	CAD	ENSG00000084774	-0.4162027845712726	[296,231]	[153,174,338]	-4	hSpCas9	negative selection	5052932
27232063	27232085	2	+	27760321	HT29	viability after 19 days	GCTCACACGCATCGACCGCTGG	CAD	ENSG00000084774	-0.31440603631123754	[973,759]	[841,882,675]	-3	hSpCas9	negative selection	5052933
27232087	27232109	2	-	27760321	HT29	viability after 19 days	GATACGCTTCATTCGGTGCAGG	CAD	ENSG00000084774	-1.2038946985310304	[755,589]	[399,246,360]	-7	hSpCas9	negative selection	5052934
27222522	27222544	2	-	27760321	HT29	viability after 19 days	CCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.06723204769667393	[341,266]	[508,303,298]	0	hSpCas9	negative selection	5052935
27217955	27217977	2	+	27760321	HT29	viability after 16 days	ATCCTCTGATCGGCAACTATGG	CAD	ENSG00000084774	-0.20614806919056577	[309,241]	[420,170,227]	-2	hSpCas9	negative selection	5136394
27231566	27231588	2	-	27760321	HT29	viability after 16 days	TACTTACCATATCGCTGACTGG	CAD	ENSG00000084774	-1.1688292368009146	[296,231]	[224,42,137]	-7	hSpCas9	negative selection	5136395
27232063	27232085	2	+	27760321	HT29	viability after 16 days	GCTCACACGCATCGACCGCTGG	CAD	ENSG00000084774	-0.26063800172868157	[973,759]	[883,575,981]	-3	hSpCas9	negative selection	5136396
27232087	27232109	2	-	27760321	HT29	viability after 16 days	GATACGCTTCATTCGGTGCAGG	CAD	ENSG00000084774	-0.3791490203137142	[755,589]	[403,394,925]	-4	hSpCas9	negative selection	5136397
27222522	27222544	2	-	27760321	HT29	viability after 16 days	CCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.08271969555821268	[341,266]	[489,127,367]	-1	hSpCas9	negative selection	5136398
27217955	27217977	2	+	27760321	HT29	viability after 13 days	ATCCTCTGATCGGCAACTATGG	CAD	ENSG00000084774	-0.4743246876705329	[309,241]	[66,312,306]	-5	hSpCas9	negative selection	5219857
27231566	27231588	2	-	27760321	HT29	viability after 13 days	TACTTACCATATCGCTGACTGG	CAD	ENSG00000084774	-0.49874972321537026	[296,231]	[244,113,287]	-5	hSpCas9	negative selection	5219858
27232063	27232085	2	+	27760321	HT29	viability after 13 days	GCTCACACGCATCGACCGCTGG	CAD	ENSG00000084774	0.02198525885868441	[973,759]	[1127,806,1121]	0	hSpCas9	negative selection	5219859
27232087	27232109	2	-	27760321	HT29	viability after 13 days	GATACGCTTCATTCGGTGCAGG	CAD	ENSG00000084774	-0.41719930687035645	[755,589]	[656,532,564]	-5	hSpCas9	negative selection	5219860
27222522	27222544	2	-	27760321	HT29	viability after 13 days	CCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.191238466724585	[341,266]	[349,455,403]	2	hSpCas9	negative selection	5219861
27217955	27217977	2	+	27760321	HT29	viability after 10 days	ATCCTCTGATCGGCAACTATGG	CAD	ENSG00000084774	-0.9875845308680895	[309,241]	[244,154,121]	-8	hSpCas9	negative selection	5303320
27231566	27231588	2	-	27760321	HT29	viability after 10 days	TACTTACCATATCGCTGACTGG	CAD	ENSG00000084774	-1.094470184094755	[296,231]	[139,201,123]	-8	hSpCas9	negative selection	5303321
27232063	27232085	2	+	27760321	HT29	viability after 10 days	GCTCACACGCATCGACCGCTGG	CAD	ENSG00000084774	0.12858877401544788	[973,759]	[1112,1174,1259]	1	hSpCas9	negative selection	5303322
27232087	27232109	2	-	27760321	HT29	viability after 10 days	GATACGCTTCATTCGGTGCAGG	CAD	ENSG00000084774	-0.179118672883541	[755,589]	[951,760,518]	-2	hSpCas9	negative selection	5303323
27222522	27222544	2	-	27760321	HT29	viability after 10 days	CCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.49357831387525686	[341,266]	[362,596,644]	6	hSpCas9	negative selection	5303324
27217955	27217977	2	+	27760321	MOLM13	viability	ATCCTCTGATCGGCAACTATGG	CAD	ENSG00000084774	-2.947804915028539	[321,309]	[0,41]	-9	hSpCas9	negative selection	5386783
27231566	27231588	2	-	27760321	MOLM13	viability	TACTTACCATATCGCTGACTGG	CAD	ENSG00000084774	-3.699472087847357	[334,296]	[10,15]	-9	hSpCas9	negative selection	5386784
27232063	27232085	2	+	27760321	MOLM13	viability	GCTCACACGCATCGACCGCTGG	CAD	ENSG00000084774	-2.2947776267155473	[1078,973]	[44,179]	-8	hSpCas9	negative selection	5386785
27232087	27232109	2	-	27760321	MOLM13	viability	GATACGCTTCATTCGGTGCAGG	CAD	ENSG00000084774	-1.486719769442516	[870,755]	[97,218]	-7	hSpCas9	negative selection	5386786
27222522	27222544	2	-	27760321	MOLM13	viability	CCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-1.4450248881432373	[407,341]	[71,81]	-7	hSpCas9	negative selection	5386787
27217386	27217409	2	-	27661255	K562	viability	GTAGGAGCCTCGGGCGCGCTTGG	CAD	ENSG00000084774	-5.32352360055532	[886,972]	[24,12]	-9	dCas9-KRAB	negative selection	5467774
27217489	27217512	2	-	27661255	K562	viability	GGAAGGACTGCAAACTCCACTGG	CAD	ENSG00000084774	-4.359815078760236	[907,1135]	[44,34]	-9	dCas9-KRAB	negative selection	5467775
27217506	27217529	2	-	27661255	K562	viability	GCGAGTACGGAGAAGCGGGAAGG	CAD	ENSG00000084774	-4.717301716352307	[545,556]	[26,7]	-9	dCas9-KRAB	negative selection	5467776
27217741	27217764	2	-	27661255	K562	viability	GGCCCATGGGCACCGAATGGGGG	CAD	ENSG00000084774	-2.349984155074341	[561,399]	[84,67]	-9	dCas9-KRAB	negative selection	5467777
27217832	27217855	2	-	27661255	K562	viability	GGCTCCGGTAGGGCACCCTTCGG	CAD	ENSG00000084774	-2.9767301610567096	[307,429]	[40,33]	-9	dCas9-KRAB	negative selection	5467778
27221238	27221261	2	-	27260156	BXPC3	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	0.049572435419540706	[651]	[631,574,750,899]	1	hSpCas9	negative selection	5533122
27222522	27222545	2	-	27260156	BXPC3	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.03550155850386194	[662]	[634,676,770,772]	0	hSpCas9	negative selection	5533123
27222519	27222542	2	+	27260156	BXPC3	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.03844282061610893	[375]	[338,457,350,475]	0	hSpCas9	negative selection	5533124
27217945	27217968	2	+	27260156	BXPC3	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.2224345162008055	[610]	[575,656,770,1031]	5	hSpCas9	negative selection	5597403
27221238	27221261	2	+	27260156	BXPC3	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.35980537201358537	[356]	[226,298,261,391]	-7	hSpCas9	negative selection	5597404
27221238	27221261	2	-	27260156	A673	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	0.11439185805961072	[651]	[755,891,897,828]	2	hSpCas9	negative selection	5654373
27222522	27222545	2	-	27260156	A673	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.030820902409320783	[662]	[821,663,750,892]	0	hSpCas9	negative selection	5654374
27222519	27222542	2	+	27260156	A673	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.02769636422862043	[375]	[443,430,394,504]	0	hSpCas9	negative selection	5654375
27217945	27217968	2	+	27260156	A673	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.3453440580854225	[610]	[1058,815,878,993]	7	hSpCas9	negative selection	5718654
27221238	27221261	2	+	27260156	A673	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.1816348170282473	[356]	[455,360,310,393]	-4	hSpCas9	negative selection	5718655
27221238	27221261	2	-	27260156	A375	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-2.377572433432053	[651]	[159,105,129,179]	-9	hSpCas9	negative selection	5775624
27222522	27222545	2	-	27260156	A375	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-1.629322399748211	[662]	[358,346,145,171]	-9	hSpCas9	negative selection	5775625
27222519	27222542	2	+	27260156	A375	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.25511330695912604	[375]	[432,453,283,317]	-4	hSpCas9	negative selection	5775626
27217945	27217968	2	+	27260156	A375	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-1.8849853434294517	[610]	[249,141,157,212]	-9	hSpCas9	negative selection	5839905
27221238	27221261	2	+	27260156	A375	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-1.8362540546105963	[356]	[63,103,239,62]	-9	hSpCas9	negative selection	5839906
27221238	27221261	2	-	27260156	COLO741	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.020534343353397044	[651]	[878,824,766]	0	hSpCas9	negative selection	5896875
27222522	27222545	2	-	27260156	COLO741	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.3360892893863656	[662]	[681,622,704]	-6	hSpCas9	negative selection	5896876
27222519	27222542	2	+	27260156	COLO741	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.31464353301196357	[375]	[343,333,469]	-6	hSpCas9	negative selection	5896877
27217945	27217968	2	+	27260156	COLO741	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.15208275096470864	[610]	[995,829,790]	3	hSpCas9	negative selection	5961156
27221238	27221261	2	+	27260156	COLO741	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.11475711885340928	[356]	[317,468,463]	-2	hSpCas9	negative selection	5961157
27221238	27221261	2	-	27260156	CAL120	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-1.4116242380470643	[651]	[250,368,286]	-9	hSpCas9	negative selection	6018126
27222522	27222545	2	-	27260156	CAL120	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-1.1180283501475043	[662]	[424,345,375]	-9	hSpCas9	negative selection	6018127
27222519	27222542	2	+	27260156	CAL120	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.245249580993521	[375]	[565,425,220]	-4	hSpCas9	negative selection	6018128
27217945	27217968	2	+	27260156	CAL120	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-1.0570332304240224	[610]	[365,408,321]	-8	hSpCas9	negative selection	6082407
27221238	27221261	2	+	27260156	CAL120	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.9269543143283887	[356]	[433,117,179]	-8	hSpCas9	negative selection	6082408
27221238	27221261	2	-	27260156	CADOES1	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	0.2501993383876461	[651]	[620,686,806,771]	4	hSpCas9	negative selection	6139377
27222522	27222545	2	-	27260156	CADOES1	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.1624247815560384	[662]	[755,470,430,544]	-3	hSpCas9	negative selection	6139378
27222519	27222542	2	+	27260156	CADOES1	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.0028849523523673537	[375]	[271,358,440,328]	0	hSpCas9	negative selection	6139379
27217945	27217968	2	+	27260156	CADOES1	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.08208332522849104	[610]	[507,668,640,587]	1	hSpCas9	negative selection	6203658
27221238	27221261	2	+	27260156	CADOES1	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.19547593033460503	[356]	[192,316,464,180]	-3	hSpCas9	negative selection	6203659
27221238	27221261	2	-	27260156	EWS502	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.04997771277911783	[651]	[497,830,743,602]	-1	hSpCas9	negative selection	6260628
27222522	27222545	2	-	27260156	EWS502	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.19141355396636917	[662]	[549,489,871,557]	-3	hSpCas9	negative selection	6260629
27222519	27222542	2	+	27260156	EWS502	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.04142175430800665	[375]	[322,421,333,579]	0	hSpCas9	negative selection	6260630
27217945	27217968	2	+	27260156	EWS502	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.010680587042963596	[610]	[520,645,781,675]	0	hSpCas9	negative selection	6324909
27221238	27221261	2	+	27260156	EWS502	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.388118632570789	[356]	[255,175,289,452]	-6	hSpCas9	negative selection	6324910
27221238	27221261	2	-	27260156	EW8	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.012559315408948113	[651]	[425,462,572,611]	0	hSpCas9	negative selection	6381879
27222522	27222545	2	-	27260156	EW8	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.07752717638152118	[662]	[683,458,290,656]	-1	hSpCas9	negative selection	6381880
27222519	27222542	2	+	27260156	EW8	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.07383102138131473	[375]	[257,432,252,342]	1	hSpCas9	negative selection	6381881
27217945	27217968	2	+	27260156	EW8	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-0.08386532924444096	[610]	[412,529,483,431]	-1	hSpCas9	negative selection	6446160
27221238	27221261	2	+	27260156	EW8	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.22421713459442977	[356]	[257,193,305,222]	-4	hSpCas9	negative selection	6446161
27221238	27221261	2	-	27260156	CORL105	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	0.31112473165654064	[651]	[1081,786,1138,817]	6	hSpCas9	negative selection	6503130
27222522	27222545	2	-	27260156	CORL105	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.11595642535778505	[662]	[792,850,939,793]	2	hSpCas9	negative selection	6503131
27222519	27222542	2	+	27260156	CORL105	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.11632235127492555	[375]	[457,330,733,427]	2	hSpCas9	negative selection	6503132
27217945	27217968	2	+	27260156	CORL105	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.24534709972173102	[610]	[783,1087,859,654]	4	hSpCas9	negative selection	6567411
27221238	27221261	2	+	27260156	CORL105	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.3821104546549207	[356]	[371,243,346,326]	-6	hSpCas9	negative selection	6567412
27221238	27221261	2	-	27260156	HS294T	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-1.077220860074244	[651]	[62,54,138,249]	-9	hSpCas9	negative selection	6624381
27222522	27222545	2	-	27260156	HS294T	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.599577367852649	[662]	[80,184,219,203]	-7	hSpCas9	negative selection	6624382
27222519	27222542	2	+	27260156	HS294T	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.08931961416326167	[375]	[75,178,101,204]	-1	hSpCas9	negative selection	6624383
27217945	27217968	2	+	27260156	HS294T	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-1.3692909034953347	[610]	[55,38,127,158]	-9	hSpCas9	negative selection	6688662
27221238	27221261	2	+	27260156	HS294T	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-1.5842494029158996	[356]	[19,31,68,69]	-9	hSpCas9	negative selection	6688663
27221238	27221261	2	-	27260156	HCC44	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-1.706220305372621	[651]	[194,173,371,191]	-9	hSpCas9	negative selection	6745632
27222522	27222545	2	-	27260156	HCC44	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-1.1832294743477871	[662]	[448,254,402,247]	-9	hSpCas9	negative selection	6745633
27222519	27222542	2	+	27260156	HCC44	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.26111356949368003	[375]	[306,263,683,230]	-4	hSpCas9	negative selection	6745634
27217945	27217968	2	+	27260156	HCC44	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-1.4773955263428116	[610]	[269,193,322,226]	-9	hSpCas9	negative selection	6809913
27221238	27221261	2	+	27260156	HCC44	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-2.057618077166677	[356]	[74,97,124,91]	-9	hSpCas9	negative selection	6809914
27221238	27221261	2	-	27260156	G402	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-1.9031393235128902	[651]	[32,55,662,69]	-9	hSpCas9	negative selection	6866883
27222522	27222545	2	-	27260156	G402	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-1.7723286229337607	[662]	[145,155,483,146]	-9	hSpCas9	negative selection	6866884
27222519	27222542	2	+	27260156	G402	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.45861286306271754	[375]	[167,198,360,562]	-5	hSpCas9	negative selection	6866885
27217945	27217968	2	+	27260156	G402	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-2.0921932593946275	[610]	[311,61,163,173]	-9	hSpCas9	negative selection	6931164
27221238	27221261	2	+	27260156	G402	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-1.1534459752926243	[356]	[127,341,109,200]	-8	hSpCas9	negative selection	6931165
27221238	27221261	2	-	27260156	L33	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.0981344124367573	[651]	[555,179,440,739]	-2	hSpCas9	negative selection	6988134
27222522	27222545	2	-	27260156	L33	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.05161818189810119	[662]	[594,303,463,675]	1	hSpCas9	negative selection	6988135
27222519	27222542	2	+	27260156	L33	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.12635477610719356	[375]	[344,197,302,333]	3	hSpCas9	negative selection	6988136
27217945	27217968	2	+	27260156	L33	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-0.07605289789021186	[610]	[477,250,364,648]	-2	hSpCas9	negative selection	7052415
27221238	27221261	2	+	27260156	L33	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.42333441819895384	[356]	[271,93,170,290]	-7	hSpCas9	negative selection	7052416
27221238	27221261	2	-	27260156	K562	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-2.381571566229109	[651]	[31,177,112,116]	-9	hSpCas9	negative selection	7109385
27222522	27222545	2	-	27260156	K562	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-1.162211427585936	[662]	[442,287,161,182]	-8	hSpCas9	negative selection	7109386
27222519	27222542	2	+	27260156	K562	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.11157027077732712	[375]	[255,735,262,213]	1	hSpCas9	negative selection	7109387
27217945	27217968	2	+	27260156	K562	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-3.504156347997498	[610]	[33,42,49,60]	-9	hSpCas9	negative selection	7173666
27221238	27221261	2	+	27260156	K562	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-2.2808906928835087	[356]	[37,126,35,60]	-9	hSpCas9	negative selection	7173667
27221238	27221261	2	-	27260156	HT29	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.17143187030059664	[651]	[847,771,512,694]	-3	hSpCas9	negative selection	7230636
27222522	27222545	2	-	27260156	HT29	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.3059089258065866	[662]	[799,769,549,520]	-5	hSpCas9	negative selection	7230637
27222519	27222542	2	+	27260156	HT29	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.01571715958503478	[375]	[450,598,443,372]	0	hSpCas9	negative selection	7230638
27217945	27217968	2	+	27260156	HT29	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-0.2735386412182103	[610]	[649,655,667,499]	-5	hSpCas9	negative selection	7294917
27221238	27221261	2	+	27260156	HT29	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.3904636135791493	[356]	[310,419,355,250]	-6	hSpCas9	negative selection	7294918
27221238	27221261	2	-	27260156	MHHES1	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	0.1329514075626933	[651]	[1003,1154,702,476]	2	hSpCas9	negative selection	7351887
27222522	27222545	2	-	27260156	MHHES1	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.17016838957155322	[662]	[965,921,739,755]	3	hSpCas9	negative selection	7351888
27222519	27222542	2	+	27260156	MHHES1	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.052245673805207005	[375]	[377,496,533,355]	1	hSpCas9	negative selection	7351889
27217945	27217968	2	+	27260156	MHHES1	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.4191618825161663	[610]	[1021,1330,927,525]	7	hSpCas9	negative selection	7416168
27221238	27221261	2	+	27260156	MHHES1	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.2245559307274611	[356]	[319,492,339,249]	-4	hSpCas9	negative selection	7416169
27221238	27221261	2	-	27260156	MEWO	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.08235460862520422	[651]	[776,413,576]	-2	hSpCas9	negative selection	7473138
27222522	27222545	2	-	27260156	MEWO	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.10262324788104565	[662]	[809,360,607]	-2	hSpCas9	negative selection	7473139
27222519	27222542	2	+	27260156	MEWO	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.17721479200149104	[375]	[412,310,228]	-4	hSpCas9	negative selection	7473140
27217945	27217968	2	+	27260156	MEWO	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.355342605749342	[610]	[828,649,733]	7	hSpCas9	negative selection	7537419
27221238	27221261	2	+	27260156	MEWO	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.31776538971021256	[356]	[308,225,276]	-6	hSpCas9	negative selection	7537420
27221238	27221261	2	-	27260156	LNCAPCLONEFGC	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-1.197439394194753	[651]	[258,200,353,233]	-9	hSpCas9	negative selection	7594389
27222522	27222545	2	-	27260156	LNCAPCLONEFGC	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.9543959656361343	[662]	[325,337,320,253]	-8	hSpCas9	negative selection	7594390
27222519	27222542	2	+	27260156	LNCAPCLONEFGC	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.05071811608375765	[375]	[338,311,420,351]	0	hSpCas9	negative selection	7594391
27217945	27217968	2	+	27260156	LNCAPCLONEFGC	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-0.8319890735021889	[610]	[361,295,381,213]	-8	hSpCas9	negative selection	7658670
27221238	27221261	2	+	27260156	LNCAPCLONEFGC	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-1.1386074384164755	[356]	[122,77,190,206]	-9	hSpCas9	negative selection	7658671
27221238	27221261	2	-	27260156	PANC0327	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	0.24971096973901907	[651]	[562,663,659,859]	3	hSpCas9	negative selection	7715640
27222522	27222545	2	-	27260156	PANC0327	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.32734852538033543	[662]	[398,395,456,628]	-5	hSpCas9	negative selection	7715641
27222519	27222542	2	+	27260156	PANC0327	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.04236952927910642	[375]	[520,367,229,267]	0	hSpCas9	negative selection	7715642
27217945	27217968	2	+	27260156	PANC0327	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-0.1523912888253256	[610]	[468,452,408,624]	-2	hSpCas9	negative selection	7779921
27221238	27221261	2	+	27260156	PANC0327	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.3089367446253823	[356]	[225,295,131,361]	-4	hSpCas9	negative selection	7779922
27221238	27221261	2	-	27260156	NCIH2009	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-2.3068863583566492	[651]	[285,190,94]	-9	hSpCas9	negative selection	7836891
27222522	27222545	2	-	27260156	NCIH2009	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.9365677178217333	[662]	[793,394,324]	-8	hSpCas9	negative selection	7836892
27222519	27222542	2	+	27260156	NCIH2009	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.6774131093705447	[375]	[398,373,224]	-7	hSpCas9	negative selection	7836893
27217945	27217968	2	+	27260156	NCIH2009	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-2.3370909715817083	[610]	[216,226,70]	-9	hSpCas9	negative selection	7901172
27221238	27221261	2	+	27260156	NCIH2009	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-2.307586595923007	[356]	[142,124,41]	-9	hSpCas9	negative selection	7901173
27221238	27221261	2	-	27260156	NCIH1373	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-1.8330849364939794	[651]	[196,82,237,83]	-9	hSpCas9	negative selection	7958142
27222522	27222545	2	-	27260156	NCIH1373	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-1.1576659775537301	[662]	[385,420,277,62]	-8	hSpCas9	negative selection	7958143
27222519	27222542	2	+	27260156	NCIH1373	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.15588779896531085	[375]	[345,286,345,143]	-1	hSpCas9	negative selection	7958144
27217945	27217968	2	+	27260156	NCIH1373	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-1.9620837598616365	[610]	[411,54,114,44]	-9	hSpCas9	negative selection	8022423
27221238	27221261	2	+	27260156	NCIH1373	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-1.510586628217548	[356]	[311,111,59,27]	-9	hSpCas9	negative selection	8022424
27221238	27221261	2	-	27260156	PATU8902	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-3.0767984479163104	[651]	[130,110,80,113]	-9	hSpCas9	negative selection	8079393
27222522	27222545	2	-	27260156	PATU8902	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-1.1156954711348424	[662]	[355,666,356,328]	-7	hSpCas9	negative selection	8079394
27222519	27222542	2	+	27260156	PATU8902	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.8124021288942717	[375]	[174,298,194,583]	-6	hSpCas9	negative selection	8079395
27217945	27217968	2	+	27260156	PATU8902	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-2.263199243638596	[610]	[211,131,223,119]	-9	hSpCas9	negative selection	8143674
27221238	27221261	2	+	27260156	PATU8902	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-1.8988939742404907	[356]	[200,89,27,253]	-9	hSpCas9	negative selection	8143675
27221238	27221261	2	-	27260156	PANC1	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	0.4694885749813531	[651]	[790,720,808,758]	7	hSpCas9	negative selection	8200644
27222522	27222545	2	-	27260156	PANC1	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.18132074539018544	[662]	[387,766,574,352]	-3	hSpCas9	negative selection	8200645
27222519	27222542	2	+	27260156	PANC1	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.130003964615926	[375]	[296,472,427,252]	2	hSpCas9	negative selection	8200646
27217945	27217968	2	+	27260156	PANC1	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.39025233573892987	[610]	[688,764,719,596]	6	hSpCas9	negative selection	8264925
27221238	27221261	2	+	27260156	PANC1	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	0.12672343389388036	[356]	[448,528,190,219]	2	hSpCas9	negative selection	8264926
27221238	27221261	2	-	27260156	PANC0813	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	0.06650789024607906	[651]	[866,881,764,703]	1	hSpCas9	negative selection	8321895
27222522	27222545	2	-	27260156	PANC0813	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.033568829779580756	[662]	[1002,678,710,811]	0	hSpCas9	negative selection	8321896
27222519	27222542	2	+	27260156	PANC0813	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.27465989867726837	[375]	[327,270,354,494]	-4	hSpCas9	negative selection	8321897
27217945	27217968	2	+	27260156	PANC0813	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-0.08309464417483181	[610]	[575,658,818,647]	-1	hSpCas9	negative selection	8386176
27221238	27221261	2	+	27260156	PANC0813	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.35959269734733684	[356]	[364,157,236,537]	-5	hSpCas9	negative selection	8386177
27221238	27221261	2	-	27260156	RDES	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	0.33263122169028525	[651]	[801,851,1183,960]	5	hSpCas9	negative selection	8443146
27222522	27222545	2	-	27260156	RDES	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.23646253705214165	[662]	[533,512,801,784]	-4	hSpCas9	negative selection	8443147
27222519	27222542	2	+	27260156	RDES	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.14132498927780923	[375]	[400,384,391,371]	-2	hSpCas9	negative selection	8443148
27217945	27217968	2	+	27260156	RDES	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.403190803956107	[610]	[751,828,1052,1139]	6	hSpCas9	negative selection	8507427
27221238	27221261	2	+	27260156	RDES	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.30225364170522356	[356]	[300,353,284,392]	-5	hSpCas9	negative selection	8507428
27221238	27221261	2	-	27260156	PC3	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.3413296234020799	[651]	[284,349,994,682]	-7	hSpCas9	negative selection	8564397
27222522	27222545	2	-	27260156	PC3	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.45245215224934276	[662]	[275,529,942,402]	-8	hSpCas9	negative selection	8564398
27222519	27222542	2	+	27260156	PC3	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.1728845911743281	[375]	[207,382,946,419]	4	hSpCas9	negative selection	8564399
27217945	27217968	2	+	27260156	PC3	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.23577354752670537	[610]	[465,529,1313,846]	5	hSpCas9	negative selection	8628678
27221238	27221261	2	+	27260156	PC3	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.26209584483164755	[356]	[229,164,388,447]	-5	hSpCas9	negative selection	8628679
27221238	27221261	2	-	27260156	PATU8988T	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.6611806809718055	[651]	[502,213,561,285]	-7	hSpCas9	negative selection	8685648
27222522	27222545	2	-	27260156	PATU8988T	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.654602680619543	[662]	[356,534,426,312]	-7	hSpCas9	negative selection	8685649
27222519	27222542	2	+	27260156	PATU8988T	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.706482407143565	[375]	[229,219,201,239]	-8	hSpCas9	negative selection	8685650
27217945	27217968	2	+	27260156	PATU8988T	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-0.4891669469216502	[610]	[426,391,473,382]	-7	hSpCas9	negative selection	8749929
27221238	27221261	2	+	27260156	PATU8988T	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.7140413234659599	[356]	[61,173,283,325]	-8	hSpCas9	negative selection	8749930
27221238	27221261	2	-	27260156	T47D	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-1.779491564530617	[651]	[248,202,228,204]	-9	hSpCas9	negative selection	8806899
27222522	27222545	2	-	27260156	T47D	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.8461469579755898	[662]	[458,437,461,355]	-9	hSpCas9	negative selection	8806900
27222519	27222542	2	+	27260156	T47D	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.25092013369487276	[375]	[445,312,364,352]	-5	hSpCas9	negative selection	8806901
27217945	27217968	2	+	27260156	T47D	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-1.0830130181067552	[610]	[300,334,315,393]	-9	hSpCas9	negative selection	8871180
27221238	27221261	2	+	27260156	T47D	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-1.001363130118327	[356]	[258,144,231,199]	-9	hSpCas9	negative selection	8871181
27221238	27221261	2	-	27260156	SU8686	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	0.034071813647331584	[651]	[631,670,637,710]	0	hSpCas9	negative selection	8928150
27222522	27222545	2	-	27260156	SU8686	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	0.20040203291728476	[662]	[802,663,757,804]	3	hSpCas9	negative selection	8928151
27222519	27222542	2	+	27260156	SU8686	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.17481386495420675	[375]	[287,278,341,438]	-3	hSpCas9	negative selection	8928152
27217945	27217968	2	+	27260156	SU8686	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.00452488876989432	[610]	[519,599,606,729]	0	hSpCas9	negative selection	8992431
27221238	27221261	2	+	27260156	SU8686	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.3223170716055051	[356]	[288,209,272,382]	-5	hSpCas9	negative selection	8992432
27221238	27221261	2	-	27260156	SKES1	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	0.3580472010429566	[651]	[833,959,710,836]	7	hSpCas9	negative selection	9049401
27222522	27222545	2	-	27260156	SKES1	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.08260589170813432	[662]	[794,669,586,485]	-2	hSpCas9	negative selection	9049402
27222519	27222542	2	+	27260156	SKES1	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.29399404281761554	[375]	[499,437,442,456]	6	hSpCas9	negative selection	9049403
27217945	27217968	2	+	27260156	SKES1	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.4389688596065962	[610]	[1149,829,825,566]	8	hSpCas9	negative selection	9113682
27221238	27221261	2	+	27260156	SKES1	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.2746379983633552	[356]	[434,281,255,227]	-6	hSpCas9	negative selection	9113683
27221238	27221261	2	-	27260156	TOV112D	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.23006226251352804	[651]	[605,583,636,413]	-4	hSpCas9	negative selection	9170652
27222522	27222545	2	-	27260156	TOV112D	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.04990952196182269	[662]	[624,813,495,669]	-1	hSpCas9	negative selection	9170653
27222519	27222542	2	+	27260156	TOV112D	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.00026364019802066485	[375]	[343,474,460,250]	0	hSpCas9	negative selection	9170654
27217945	27217968	2	+	27260156	TOV112D	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.46592774072308757	[610]	[719,1021,844,825]	8	hSpCas9	negative selection	9234933
27221238	27221261	2	+	27260156	TOV112D	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.7263255477152082	[356]	[232,308,151,194]	-9	hSpCas9	negative selection	9234934
27221238	27221261	2	-	27260156	TC71	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	0.021623452686921174	[651]	[590,816,632,807]	0	hSpCas9	negative selection	9291903
27222522	27222545	2	-	27260156	TC71	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.28617027404206224	[662]	[647,539,594,543]	-7	hSpCas9	negative selection	9291904
27222519	27222542	2	+	27260156	TC71	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	0.026358421386219077	[375]	[428,307,409,499]	0	hSpCas9	negative selection	9291905
27217945	27217968	2	+	27260156	TC71	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	0.2862800217660674	[610]	[691,953,799,747]	7	hSpCas9	negative selection	9356184
27221238	27221261	2	+	27260156	TC71	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.15531002758724927	[356]	[332,234,358,453]	-4	hSpCas9	negative selection	9356185
27221238	27221261	2	-	27260156	TC32	viability	CCACTACCAGTGCTGCTACGTGG	CAD	ENSG00000084774	-0.25274183030073166	[651]	[478,424,679,507]	-4	hSpCas9	negative selection	9413154
27222522	27222545	2	-	27260156	TC32	viability	CCCCCTGTATTGAATACCCGTGG	CAD	ENSG00000084774	-0.11092531748033757	[662]	[532,466,540,783]	-2	hSpCas9	negative selection	9413155
27222519	27222542	2	+	27260156	TC32	viability	ACTCCACGGGTATTCAATACAGG	CAD	ENSG00000084774	-0.3048667767067331	[375]	[227,281,390,249]	-5	hSpCas9	negative selection	9413156
27217945	27217968	2	+	27260156	TC32	viability	GTGCTCACCTATCCTCTGATCGG	CAD	ENSG00000084774	-0.538379334846963	[610]	[294,229,739,432]	-8	hSpCas9	negative selection	9477435
27221238	27221261	2	+	27260156	TC32	viability	CCACGTAGCAGCACTGGTAGTGG	CAD	ENSG00000084774	-0.7478364192651592	[356]	[205,146,260,202]	-9	hSpCas9	negative selection	9477436
27217555	27217578	2	+	27869803	HPAFII	viability after 27 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-5.232290882402685	[324]	[3,4,NaN]	-9	hSpCas9	negative selection	9574577
27221335	27221358	2	-	27869803	HPAFII	viability after 27 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.3826411540802631	[264]	[227,142,NaN]	3	hSpCas9	negative selection	9574578
27222213	27222236	2	+	27869803	HPAFII	viability after 27 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	-1.7502416550405455	[209]	[46,20,NaN]	-8	hSpCas9	negative selection	9574579
27222548	27222571	2	-	27869803	HPAFII	viability after 27 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-6.252328635639231	[144]	[0,0,NaN]	-9	hSpCas9	negative selection	9574580
27222877	27222900	2	+	27869803	HPAFII	viability after 27 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.5374968824291413	[197]	[101,191,NaN]	4	hSpCas9	negative selection	9574581
27223738	27223761	2	-	27869803	HPAFII	viability after 27 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-1.2908430647577989	[296]	[113,21,NaN]	-7	hSpCas9	negative selection	9574582
27217555	27217578	2	+	27869803	HPAFII	viability after 15 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-2.675136811090441	[324]	[95,28,NaN]	-9	hSpCas9	negative selection	9657026
27221335	27221358	2	-	27869803	HPAFII	viability after 15 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.8375087068338807	[264]	[503,511,NaN]	8	hSpCas9	negative selection	9657027
27222213	27222236	2	+	27869803	HPAFII	viability after 15 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	-0.5287711156422188	[209]	[206,124,NaN]	-5	hSpCas9	negative selection	9657028
27222548	27222571	2	-	27869803	HPAFII	viability after 15 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-7.283883373769103	[144]	[0,0,NaN]	-9	hSpCas9	negative selection	9657029
27222877	27222900	2	+	27869803	HPAFII	viability after 15 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.6289382286792129	[197]	[407,279,NaN]	7	hSpCas9	negative selection	9657030
27223738	27223761	2	-	27869803	HPAFII	viability after 15 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-1.3601147516338452	[296]	[222,62,NaN]	-8	hSpCas9	negative selection	9657031
27217555	27217578	2	+	27869803	ASPC1	viability after 36 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-0.8651741388299932	[783]	[165,247,59]	-7	hSpCas9	negative selection	9739475
27221335	27221358	2	-	27869803	ASPC1	viability after 36 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	-0.09591287660114432	[594]	[270,228,110]	-1	hSpCas9	negative selection	9739476
27222213	27222236	2	+	27869803	ASPC1	viability after 36 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	-0.9019543222309772	[472]	[133,103,42]	-7	hSpCas9	negative selection	9739477
27222548	27222571	2	-	27869803	ASPC1	viability after 36 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-0.2729716472903898	[259]	[149,94,5]	-3	hSpCas9	negative selection	9739478
27222877	27222900	2	+	27869803	ASPC1	viability after 36 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	-0.1266817838898956	[396]	[270,114,33]	-1	hSpCas9	negative selection	9739479
27223738	27223761	2	-	27869803	ASPC1	viability after 36 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-0.8709427170095058	[994]	[282,230,89]	-7	hSpCas9	negative selection	9739480
27217555	27217578	2	+	27869803	PATU8988S	viability after 35 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-1.2130676691745592	[627]	[152,64,NaN]	-8	hSpCas9	negative selection	9821924
27221335	27221358	2	-	27869803	PATU8988S	viability after 35 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.8269420162414441	[519]	[376,365,NaN]	8	hSpCas9	negative selection	9821925
27222213	27222236	2	+	27869803	PATU8988S	viability after 35 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	0.671768258191583	[321]	[246,165,NaN]	7	hSpCas9	negative selection	9821926
27222548	27222571	2	-	27869803	PATU8988S	viability after 35 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-2.0954669129802963	[217]	[39,0,NaN]	-9	hSpCas9	negative selection	9821927
27222877	27222900	2	+	27869803	PATU8988S	viability after 35 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.2993053787699783	[339]	[170,165,NaN]	3	hSpCas9	negative selection	9821928
27223738	27223761	2	-	27869803	PATU8988S	viability after 35 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-2.223437278333714	[841]	[122,21,NaN]	-9	hSpCas9	negative selection	9821929
27217555	27217578	2	+	27869803	PATU8988S	viability after 31 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-1.0148809266054046	[627]	[126,119,NaN]	-7	hSpCas9	negative selection	9904373
27221335	27221358	2	-	27869803	PATU8988S	viability after 31 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.7465915737141963	[519]	[401,278,NaN]	8	hSpCas9	negative selection	9904374
27222213	27222236	2	+	27869803	PATU8988S	viability after 31 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	0.318500364092421	[321]	[127,200,NaN]	4	hSpCas9	negative selection	9904375
27222548	27222571	2	-	27869803	PATU8988S	viability after 31 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-2.082649902026513	[217]	[27,10,NaN]	-9	hSpCas9	negative selection	9904376
27222877	27222900	2	+	27869803	PATU8988S	viability after 31 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	-0.014200295967503829	[339]	[157,103,NaN]	0	hSpCas9	negative selection	9904377
27223738	27223761	2	-	27869803	PATU8988S	viability after 31 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-2.10203722999542	[841]	[97,52,NaN]	-9	hSpCas9	negative selection	9904378
27217555	27217578	2	+	27869803	HPAFII	viability after 35 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-7.362207354919143	[324]	[0,0,NaN]	-9	hSpCas9	negative selection	9986822
27221335	27221358	2	-	27869803	HPAFII	viability after 35 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	-0.3387640274224417	[264]	[146,59,NaN]	-2	hSpCas9	negative selection	9986823
27222213	27222236	2	+	27869803	HPAFII	viability after 35 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	-2.088757035189762	[209]	[8,42,NaN]	-8	hSpCas9	negative selection	9986824
27222548	27222571	2	-	27869803	HPAFII	viability after 35 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-6.19782053701826	[144]	[0,0,NaN]	-9	hSpCas9	negative selection	9986825
27222877	27222900	2	+	27869803	HPAFII	viability after 35 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	-0.23004928602707703	[197]	[68,103,NaN]	-1	hSpCas9	negative selection	9986826
27223738	27223761	2	-	27869803	HPAFII	viability after 35 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-2.114726054081515	[296]	[53,12,NaN]	-8	hSpCas9	negative selection	9986827
27217555	27217578	2	+	27869803	HPAFII	viability after 31 days	GCGGCCCTAGTGTTGGAGGACGG	CAD	ENSG00000084774	-5.885320223022058	[324]	[4,0,NaN]	-9	hSpCas9	negative selection	10069271
27221335	27221358	2	-	27869803	HPAFII	viability after 31 days	GCCACCATACCTTGCAAGCCAGG	CAD	ENSG00000084774	0.43805639259991147	[264]	[256,140,NaN]	3	hSpCas9	negative selection	10069272
27222213	27222236	2	+	27869803	HPAFII	viability after 31 days	GACCAAGAAGTTGCGGGAACAGG	CAD	ENSG00000084774	-1.8773363281562587	[209]	[44,17,NaN]	-8	hSpCas9	negative selection	10069273
27222548	27222571	2	-	27869803	HPAFII	viability after 31 days	AGTCCAAAGCAAGGATCCGAGGG	CAD	ENSG00000084774	-6.346537890339677	[144]	[0,0,NaN]	-9	hSpCas9	negative selection	10069274
27222877	27222900	2	+	27869803	HPAFII	viability after 31 days	CTCTTCTTAAGTAATGGGCCTGG	CAD	ENSG00000084774	0.0032499379085714764	[197]	[74,150,NaN]	0	hSpCas9	negative selection	10069275
27223738	27223761	2	-	27869803	HPAFII	viability after 31 days	AACCAGGCTCACCTGAAGAAAGG	CAD	ENSG00000084774	-1.8770086342696861	[296]	[64,23,NaN]	-8	hSpCas9	negative selection	10069276
27225875	27225898	2	+	28162770	P31FUJ	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-4.708535635380776	[266]	[11]	-9	hSpCas9	negative selection	10125103
27225820	27225843	2	-	28162770	P31FUJ	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-4.792229613028397	[447]	[18]	-9	hSpCas9	negative selection	10125104
27239211	27239234	2	+	28162770	P31FUJ	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-3.9065739720933905	[267]	[20]	-9	hSpCas9	negative selection	10125105
27240279	27240302	2	-	28162770	P31FUJ	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-0.2933437463494293	[72]	[69]	-3	hSpCas9	negative selection	10125106
27221298	27221321	2	-	28162770	P31FUJ	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-2.4366745377800285	[386]	[83]	-8	hSpCas9	negative selection	10125107
27222206	27222229	2	+	28162770	P31FUJ	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-1.771594523702609	[368]	[126]	-8	hSpCas9	negative selection	10125108
27222281	27222304	2	-	28162770	P31FUJ	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-1.719426785942242	[240]	[85]	-8	hSpCas9	negative selection	10125109
27222608	27222631	2	+	28162770	P31FUJ	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-3.9297697306486654	[414]	[31]	-9	hSpCas9	negative selection	10125110
27224803	27224826	2	+	28162770	P31FUJ	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-2.8517120370588724	[601]	[97]	-9	hSpCas9	negative selection	10125111
27225743	27225766	2	+	28162770	P31FUJ	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-3.0235742422763785	[518]	[74]	-9	hSpCas9	negative selection	10125112
27225875	27225898	2	+	28162770	TF1	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10294469
27225820	27225843	2	-	28162770	TF1	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10294470
27239211	27239234	2	+	28162770	TF1	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10294471
27240279	27240302	2	-	28162770	TF1	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10294472
27221298	27221321	2	-	28162770	TF1	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	NaN	[NaN]	[27]	1	hSpCas9	negative selection	10294473
27222206	27222229	2	+	28162770	TF1	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	NaN	[NaN]	[88]	1	hSpCas9	negative selection	10294474
27222281	27222304	2	-	28162770	TF1	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10294475
27222608	27222631	2	+	28162770	TF1	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10294476
27224803	27224826	2	+	28162770	TF1	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10294477
27225743	27225766	2	+	28162770	TF1	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10294478
27225875	27225898	2	+	28162770	SKM1	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-3.1865741303178616	[102]	[19]	-9	hSpCas9	negative selection	10463835
27225820	27225843	2	-	28162770	SKM1	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-3.77196101552241	[84]	[10]	-9	hSpCas9	negative selection	10463836
27239211	27239234	2	+	28162770	SKM1	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-3.104935661293504	[72]	[14]	-9	hSpCas9	negative selection	10463837
27240279	27240302	2	-	28162770	SKM1	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-1.4933789505606352	[42]	[26]	-7	hSpCas9	negative selection	10463838
27221298	27221321	2	-	28162770	SKM1	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-2.429159944857358	[130]	[42]	-8	hSpCas9	negative selection	10463839
27222206	27222229	2	+	28162770	SKM1	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-2.7626231509430736	[118]	[30]	-9	hSpCas9	negative selection	10463840
27222281	27222304	2	-	28162770	SKM1	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-1.8834022426861488	[47]	[22]	-8	hSpCas9	negative selection	10463841
27222608	27222631	2	+	28162770	SKM1	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-2.9305261548001744	[68]	[15]	-9	hSpCas9	negative selection	10463842
27224803	27224826	2	+	28162770	SKM1	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-3.108882845810167	[121]	[24]	-9	hSpCas9	negative selection	10463843
27225743	27225766	2	+	28162770	SKM1	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-4.484966710744435	[113]	[8]	-9	hSpCas9	negative selection	10463844
27225875	27225898	2	+	28162770	SKM1	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-3.1865741303178616	[102]	[19]	-9	hSpCas9	negative selection	10633201
27225820	27225843	2	-	28162770	SKM1	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-3.77196101552241	[84]	[10]	-9	hSpCas9	negative selection	10633202
27239211	27239234	2	+	28162770	SKM1	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-3.104935661293504	[72]	[14]	-9	hSpCas9	negative selection	10633203
27240279	27240302	2	-	28162770	SKM1	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-1.4933789505606352	[42]	[26]	-7	hSpCas9	negative selection	10633204
27221298	27221321	2	-	28162770	SKM1	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-2.429159944857358	[130]	[42]	-8	hSpCas9	negative selection	10633205
27222206	27222229	2	+	28162770	SKM1	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-2.7626231509430736	[118]	[30]	-9	hSpCas9	negative selection	10633206
27222281	27222304	2	-	28162770	SKM1	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-1.8834022426861488	[47]	[22]	-8	hSpCas9	negative selection	10633207
27222608	27222631	2	+	28162770	SKM1	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-2.9305261548001744	[68]	[15]	-9	hSpCas9	negative selection	10633208
27224803	27224826	2	+	28162770	SKM1	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-3.108882845810167	[121]	[24]	-9	hSpCas9	negative selection	10633209
27225743	27225766	2	+	28162770	SKM1	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-4.484966710744435	[113]	[8]	-9	hSpCas9	negative selection	10633210
27225875	27225898	2	+	28162770	PL21	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-2.626711483194081	[297]	[20]	-9	hSpCas9	negative selection	10802567
27225820	27225843	2	-	28162770	PL21	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-2.2701803202907134	[265]	[23]	-8	hSpCas9	negative selection	10802568
27239211	27239234	2	+	28162770	PL21	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-1.719241925302395	[173]	[22]	-8	hSpCas9	negative selection	10802569
27240279	27240302	2	-	28162770	PL21	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-3.7694867364671616	[93]	[2]	-9	hSpCas9	negative selection	10802570
27221298	27221321	2	-	28162770	PL21	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-1.7827463646468322	[418]	[52]	-8	hSpCas9	negative selection	10802571
27222206	27222229	2	+	28162770	PL21	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-0.804598304517343	[304]	[75]	-5	hSpCas9	negative selection	10802572
27222281	27222304	2	-	28162770	PL21	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-0.9827244426604904	[167]	[36]	-6	hSpCas9	negative selection	10802573
27222608	27222631	2	+	28162770	PL21	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-5.85514282101187	[265]	[1]	-9	hSpCas9	negative selection	10802574
27224803	27224826	2	+	28162770	PL21	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-1.8736806188023514	[420]	[49]	-8	hSpCas9	negative selection	10802575
27225743	27225766	2	+	28162770	PL21	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-2.8731093675413186	[403]	[23]	-9	hSpCas9	negative selection	10802576
27225875	27225898	2	+	28162770	P31FUJ	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-4.708535635380776	[266]	[11]	-9	hSpCas9	negative selection	10971933
27225820	27225843	2	-	28162770	P31FUJ	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-4.792229613028397	[447]	[18]	-9	hSpCas9	negative selection	10971934
27239211	27239234	2	+	28162770	P31FUJ	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-3.9065739720933905	[267]	[20]	-9	hSpCas9	negative selection	10971935
27240279	27240302	2	-	28162770	P31FUJ	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-0.2933437463494293	[72]	[69]	-3	hSpCas9	negative selection	10971936
27221298	27221321	2	-	28162770	P31FUJ	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-2.4366745377800285	[386]	[83]	-8	hSpCas9	negative selection	10971937
27222206	27222229	2	+	28162770	P31FUJ	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-1.771594523702609	[368]	[126]	-8	hSpCas9	negative selection	10971938
27222281	27222304	2	-	28162770	P31FUJ	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-1.719426785942242	[240]	[85]	-8	hSpCas9	negative selection	10971939
27222608	27222631	2	+	28162770	P31FUJ	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-3.9297697306486654	[414]	[31]	-9	hSpCas9	negative selection	10971940
27224803	27224826	2	+	28162770	P31FUJ	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-2.8517120370588724	[601]	[97]	-9	hSpCas9	negative selection	10971941
27225743	27225766	2	+	28162770	P31FUJ	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-3.0235742422763785	[518]	[74]	-9	hSpCas9	negative selection	10971942
27225875	27225898	2	+	28162770	OCIAML5	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-8.398961030751634	[186]	[0]	-9	hSpCas9	negative selection	11141299
27225820	27225843	2	-	28162770	OCIAML5	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-6.291689708421114	[216]	[4]	-9	hSpCas9	negative selection	11141300
27239211	27239234	2	+	28162770	OCIAML5	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-4.458724142684472	[133]	[10]	-9	hSpCas9	negative selection	11141301
27240279	27240302	2	-	28162770	OCIAML5	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-3.6594214929216013	[62]	[8]	-9	hSpCas9	negative selection	11141302
27221298	27221321	2	-	28162770	OCIAML5	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-3.0258960267622257	[184]	[40]	-8	hSpCas9	negative selection	11141303
27222206	27222229	2	+	28162770	OCIAML5	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-1.9185619826509037	[221]	[105]	-7	hSpCas9	negative selection	11141304
27222281	27222304	2	-	28162770	OCIAML5	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-2.5828799380486083	[155]	[46]	-8	hSpCas9	negative selection	11141305
27222608	27222631	2	+	28162770	OCIAML5	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-6.646482437214103	[221]	[3]	-9	hSpCas9	negative selection	11141306
27224803	27224826	2	+	28162770	OCIAML5	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-4.1084063241237825	[343]	[35]	-9	hSpCas9	negative selection	11141307
27225743	27225766	2	+	28162770	OCIAML5	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-4.552506289005089	[259]	[19]	-9	hSpCas9	negative selection	11141308
27225875	27225898	2	+	28162770	EOL1	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-3.3973803233168276	[559]	[27]	-9	hSpCas9	negative selection	11310665
27225820	27225843	2	-	28162770	EOL1	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-0.7053406000321378	[423]	[136]	-5	hSpCas9	negative selection	11310666
27239211	27239234	2	+	28162770	EOL1	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-3.626626415694338	[421]	[17]	-9	hSpCas9	negative selection	11310667
27240279	27240302	2	-	28162770	EOL1	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-3.162915069679805	[203]	[11]	-9	hSpCas9	negative selection	11310668
27221298	27221321	2	-	28162770	EOL1	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-2.5882209044124758	[798]	[69]	-9	hSpCas9	negative selection	11310669
27222206	27222229	2	+	28162770	EOL1	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-1.908880662096963	[669]	[93]	-8	hSpCas9	negative selection	11310670
27222281	27222304	2	-	28162770	EOL1	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-1.4336438673035994	[281]	[54]	-7	hSpCas9	negative selection	11310671
27222608	27222631	2	+	28162770	EOL1	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-1.8340628166356514	[290]	[42]	-8	hSpCas9	negative selection	11310672
27224803	27224826	2	+	28162770	EOL1	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-2.9151169169214337	[586]	[40]	-9	hSpCas9	negative selection	11310673
27225743	27225766	2	+	28162770	EOL1	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-3.2908918891241465	[482]	[25]	-9	hSpCas9	negative selection	11310674
27225875	27225898	2	+	28162770	MOLM13	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-4.200489127364214	[355]	[13]	-9	hSpCas9	negative selection	11480031
27225820	27225843	2	-	28162770	MOLM13	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-8.215105202137105	[410]	[0]	-9	hSpCas9	negative selection	11480032
27239211	27239234	2	+	28162770	MOLM13	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-2.597066060296191	[317]	[37]	-8	hSpCas9	negative selection	11480033
27240279	27240302	2	-	28162770	MOLM13	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-1.0230969709675637	[103]	[36]	-5	hSpCas9	negative selection	11480034
27221298	27221321	2	-	28162770	MOLM13	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-3.270547599838295	[653]	[48]	-8	hSpCas9	negative selection	11480035
27222206	27222229	2	+	28162770	MOLM13	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-2.572916834843307	[501]	[60]	-8	hSpCas9	negative selection	11480036
27222281	27222304	2	-	28162770	MOLM13	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-3.6641390121392052	[262]	[14]	-9	hSpCas9	negative selection	11480037
27222608	27222631	2	+	28162770	MOLM13	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-8.165105815598379	[396]	[0]	-9	hSpCas9	negative selection	11480038
27224803	27224826	2	+	28162770	MOLM13	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-4.166703886901177	[620]	[24]	-9	hSpCas9	negative selection	11480039
27225743	27225766	2	+	28162770	MOLM13	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-4.6806619691051665	[602]	[16]	-9	hSpCas9	negative selection	11480040
27225875	27225898	2	+	28162770	HEL	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-3.558895029169294	[367]	[19]	-9	hSpCas9	negative selection	11649397
27225820	27225843	2	-	28162770	HEL	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-6.0047195944545635	[400]	[3]	-9	hSpCas9	negative selection	11649398
27239211	27239234	2	+	28162770	HEL	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-3.5187245906937594	[339]	[18]	-9	hSpCas9	negative selection	11649399
27240279	27240302	2	-	28162770	HEL	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-1.5371702580145774	[144]	[31]	-7	hSpCas9	negative selection	11649400
27221298	27221321	2	-	28162770	HEL	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-1.8166927866369402	[582]	[105]	-7	hSpCas9	negative selection	11649401
27222206	27222229	2	+	28162770	HEL	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-2.0300964247461337	[439]	[68]	-8	hSpCas9	negative selection	11649402
27222281	27222304	2	-	28162770	HEL	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-1.5748526030722698	[199]	[42]	-7	hSpCas9	negative selection	11649403
27222608	27222631	2	+	28162770	HEL	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-5.159454384941468	[278]	[4]	-9	hSpCas9	negative selection	11649404
27224803	27224826	2	+	28162770	HEL	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-3.3056283995843208	[493]	[31]	-9	hSpCas9	negative selection	11649405
27225743	27225766	2	+	28162770	HEL	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-5.054614906266993	[466]	[8]	-9	hSpCas9	negative selection	11649406
27225875	27225898	2	+	28162770	MV411	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-3.796956568575678	[362]	[21]	-9	hSpCas9	negative selection	11818763
27225820	27225843	2	-	28162770	MV411	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-3.643333379462466	[266]	[17]	-9	hSpCas9	negative selection	11818764
27239211	27239234	2	+	28162770	MV411	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-3.1639886949436895	[265]	[24]	-9	hSpCas9	negative selection	11818765
27240279	27240302	2	-	28162770	MV411	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-1.6438561897747244	[114]	[30]	-7	hSpCas9	negative selection	11818766
27221298	27221321	2	-	28162770	MV411	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-1.6199246806391059	[404]	[110]	-7	hSpCas9	negative selection	11818767
27222206	27222229	2	+	28162770	MV411	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-0.09324450416994928	[270]	[213]	0	hSpCas9	negative selection	11818768
27222281	27222304	2	-	28162770	MV411	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-2.559917371274829	[104]	[14]	-9	hSpCas9	negative selection	11818769
27222608	27222631	2	+	28162770	MV411	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-3.1773677247448897	[246]	[22]	-9	hSpCas9	negative selection	11818770
27224803	27224826	2	+	28162770	MV411	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-1.5083870706347469	[384]	[113]	-7	hSpCas9	negative selection	11818771
27225743	27225766	2	+	28162770	MV411	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-1.9822968458948407	[393]	[83]	-8	hSpCas9	negative selection	11818772
27225875	27225898	2	+	28162770	MONOMAC1	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-2.055860784098859	[213]	[58]	-9	hSpCas9	negative selection	11988129
27225820	27225843	2	-	28162770	MONOMAC1	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-4.139551352398794	[245]	[15]	-9	hSpCas9	negative selection	11988130
27239211	27239234	2	+	28162770	MONOMAC1	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-2.9022935814984216	[149]	[22]	-9	hSpCas9	negative selection	11988131
27240279	27240302	2	-	28162770	MONOMAC1	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-1.5340718343371245	[47]	[18]	-8	hSpCas9	negative selection	11988132
27221298	27221321	2	-	28162770	MONOMAC1	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-2.4077474633483664	[286]	[61]	-9	hSpCas9	negative selection	11988133
27222206	27222229	2	+	28162770	MONOMAC1	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-0.9957060412509354	[206]	[118]	-7	hSpCas9	negative selection	11988134
27222281	27222304	2	-	28162770	MONOMAC1	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-1.6248983866959812	[112]	[41]	-8	hSpCas9	negative selection	11988135
27222608	27222631	2	+	28162770	MONOMAC1	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-2.3363116356616813	[162]	[36]	-9	hSpCas9	negative selection	11988136
27224803	27224826	2	+	28162770	MONOMAC1	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-0.27390561044382433	[211]	[200]	-2	hSpCas9	negative selection	11988137
27225743	27225766	2	+	28162770	MONOMAC1	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-1.7871610528964887	[279]	[92]	-8	hSpCas9	negative selection	11988138
27225875	27225898	2	+	28162770	OCIAML2	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-2.3331263014922263	[49]	[54]	-8	hSpCas9	negative selection	12157495
27225820	27225843	2	-	28162770	OCIAML2	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-5.4706298252421615	[63]	[7]	-9	hSpCas9	negative selection	12157496
27239211	27239234	2	+	28162770	OCIAML2	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-3.444634616709217	[54]	[27]	-9	hSpCas9	negative selection	12157497
27240279	27240302	2	-	28162770	OCIAML2	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-2.470629825242161	[18]	[18]	-8	hSpCas9	negative selection	12157498
27221298	27221321	2	-	28162770	OCIAML2	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-2.2406242197958384	[80]	[94]	-8	hSpCas9	negative selection	12157499
27222206	27222229	2	+	28162770	OCIAML2	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-1.7172697928252867	[69]	[117]	-8	hSpCas9	negative selection	12157500
27222281	27222304	2	-	28162770	OCIAML2	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-2.9012641795720233	[30]	[22]	-9	hSpCas9	negative selection	12157501
27222608	27222631	2	+	28162770	OCIAML2	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-2.8539584647936667	[29]	[22]	-9	hSpCas9	negative selection	12157502
27224803	27224826	2	+	28162770	OCIAML2	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-2.643466422104377	[61]	[54]	-9	hSpCas9	negative selection	12157503
27225743	27225766	2	+	28162770	OCIAML2	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-3.0362270010963863	[73]	[49]	-9	hSpCas9	negative selection	12157504
27225875	27225898	2	+	28162770	OCIAML3	viability	GAAGGAGATTGAGTACGAGGTGG	CAD	ENSG00000084774	-1.936399837771241	[70]	[55]	-8	hSpCas9	negative selection	12326861
27225820	27225843	2	-	28162770	OCIAML3	viability	GCTGGTATGGGCAAAAGCTGGGG	CAD	ENSG00000084774	-5.193920482511291	[96]	[7]	-9	hSpCas9	negative selection	12326862
27239211	27239234	2	+	28162770	OCIAML3	viability	GCAGGAGGACACCTATGTGGAGG	CAD	ENSG00000084774	-2.972519263577893	[64]	[24]	-9	hSpCas9	negative selection	12326863
27240279	27240302	2	-	28162770	OCIAML3	viability	GAAGCCCTGGGATGCCACGGCGG	CAD	ENSG00000084774	-2.1414954356266565	[18]	[12]	-8	hSpCas9	negative selection	12326864
27221298	27221321	2	-	28162770	OCIAML3	viability	GCAGCCACTCATGCAGGGTGCGG	CAD	ENSG00000084774	-2.7433852643623897	[121]	[54]	-9	hSpCas9	negative selection	12326865
27222206	27222229	2	+	28162770	OCIAML3	viability	GGGAGCTGACCAAGAAGTTGCGG	CAD	ENSG00000084774	-1.2000934326110735	[85]	[112]	-7	hSpCas9	negative selection	12326866
27222281	27222304	2	-	28162770	OCIAML3	viability	ATTGGGGTCCAAGAATGGCAGGG	CAD	ENSG00000084774	-1.6220220164937598	[51]	[50]	-8	hSpCas9	negative selection	12326867
27222608	27222631	2	+	28162770	OCIAML3	viability	GCGTGGGGCTGAGGTCACTGTGG	CAD	ENSG00000084774	-2.6375092789607497	[100]	[48]	-9	hSpCas9	negative selection	12326868
27224803	27224826	2	+	28162770	OCIAML3	viability	CCACAGTGCAGACCTCCCAGGGG	CAD	ENSG00000084774	-1.3681262329078354	[117]	[137]	-7	hSpCas9	negative selection	12326869
27225743	27225766	2	+	28162770	OCIAML3	viability	AGTGCGTGCAGCCTTTGCCCTGG	CAD	ENSG00000084774	-2.521251297888849	[115]	[60]	-9	hSpCas9	negative selection	12326870