Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:80184
• Symbol:cep290
• Description:centrosomal protein 290

DataSource: http://genomecrispr.dkfz.de/#!/results/cep290

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
88139144	88139167	12	-	26472758	Jiyoye	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	1.4219219668750598	[145]	[294]	8	hSpCas9	negative selection	30074
88120113	88120136	12	-	26472758	Jiyoye	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	1.1055196816447723	[52]	[85]	7	hSpCas9	negative selection	30075
88102837	88102860	12	-	26472758	Jiyoye	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.7085560989891498	[197]	[243]	5	hSpCas9	negative selection	30076
88131197	88131220	12	-	26472758	Jiyoye	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.7097381515263046	[149]	[184]	5	hSpCas9	negative selection	30077
88121062	88121085	12	-	26472758	Jiyoye	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	5.162062883669342	[0]	[26]	9	hSpCas9	negative selection	30078
88093805	88093828	12	-	26472758	Jiyoye	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.462670494097577	[152]	[158]	3	hSpCas9	negative selection	30079
88084708	88084731	12	-	26472758	Jiyoye	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	-2.578885427536253	[102]	[12]	-9	hSpCas9	negative selection	30080
88077254	88077277	12	-	26472758	Jiyoye	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-0.5188240370503496	[37]	[19]	-4	hSpCas9	negative selection	30081
88054367	88054390	12	-	26472758	Jiyoye	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	-0.37594433774458635	[486]	[282]	-3	hSpCas9	negative selection	30082
88136669	88136692	12	-	26472758	Jiyoye	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-0.8520169580335261	[224]	[93]	-5	hSpCas9	negative selection	30083
88139144	88139167	12	-	26472758	KBM7	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.11816049581343213	[1106,923]	[676,371]	1	hSpCas9	negative selection	221192
88120113	88120136	12	-	26472758	KBM7	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	0.32226938333586963	[231,190]	[166,84]	3	hSpCas9	negative selection	221193
88102837	88102860	12	-	26472758	KBM7	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.043750046704325696	[1170,813]	[577,381]	0	hSpCas9	negative selection	221194
88131197	88131220	12	-	26472758	KBM7	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.009141248234772359	[845,752]	[445,316]	0	hSpCas9	negative selection	221195
88121062	88121085	12	-	26472758	KBM7	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	0.09533735343155403	[100,90]	[34,59]	0	hSpCas9	negative selection	221196
88093805	88093828	12	-	26472758	KBM7	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.3302256055920145	[682,468]	[473,211]	3	hSpCas9	negative selection	221197
88084708	88084731	12	-	26472758	KBM7	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	0.8285884014950361	[317,234]	[332,134]	8	hSpCas9	negative selection	221198
88077254	88077277	12	-	26472758	KBM7	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	1.1020825824145897	[44,45]	[32,57]	9	hSpCas9	negative selection	221199
88054367	88054390	12	-	26472758	KBM7	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	0.11759455311868172	[1557,1442]	[885,658]	1	hSpCas9	negative selection	221200
88136669	88136692	12	-	26472758	KBM7	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-1.3126573648236206	[828,926]	[149,183]	-7	hSpCas9	negative selection	221201
88139144	88139167	12	-	26472758	Raji	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.7886296882813808	[453]	[181]	7	hSpCas9	negative selection	412310
88120113	88120136	12	-	26472758	Raji	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	0.6970995660653903	[100]	[37]	6	hSpCas9	negative selection	412311
88102837	88102860	12	-	26472758	Raji	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.6679038948284428	[376]	[138]	6	hSpCas9	negative selection	412312
88131197	88131220	12	-	26472758	Raji	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.999468196206712	[221]	[102]	8	hSpCas9	negative selection	412313
88121062	88121085	12	-	26472758	Raji	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	1.7594602319532924	[13]	[10]	9	hSpCas9	negative selection	412314
88093805	88093828	12	-	26472758	Raji	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.3447122270149184	[301]	[88]	3	hSpCas9	negative selection	412315
88084708	88084731	12	-	26472758	Raji	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	-0.1150088859628483	[181]	[38]	-1	hSpCas9	negative selection	412316
88077254	88077277	12	-	26472758	Raji	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-3.3188812193284987	[42]	[0]	-9	hSpCas9	negative selection	412317
88054367	88054390	12	-	26472758	Raji	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	0.07974078030447074	[684]	[167]	0	hSpCas9	negative selection	412318
88136669	88136692	12	-	26472758	Raji	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-0.512512755456944	[417]	[67]	-4	hSpCas9	negative selection	412319
88139144	88139167	12	-	26472758	K562	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.7902334905705877	[771]	[1126]	6	hSpCas9	negative selection	603428
88120113	88120136	12	-	26472758	K562	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	-0.322949713039971	[162]	[109]	-2	hSpCas9	negative selection	603429
88102837	88102860	12	-	26472758	K562	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.10921178623354777	[815]	[742]	0	hSpCas9	negative selection	603430
88131197	88131220	12	-	26472758	K562	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.5151338705818646	[561]	[677]	4	hSpCas9	negative selection	603431
88121062	88121085	12	-	26472758	K562	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	0.10286458345242777	[106]	[96]	0	hSpCas9	negative selection	603432
88093805	88093828	12	-	26472758	K562	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.45872056167659825	[561]	[651]	3	hSpCas9	negative selection	603433
88084708	88084731	12	-	26472758	K562	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	1.4443562981751987	[147]	[339]	9	hSpCas9	negative selection	603434
88077254	88077277	12	-	26472758	K562	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	1.8395769954934917	[46]	[141]	9	hSpCas9	negative selection	603435
88054367	88054390	12	-	26472758	K562	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	0.4243832242123371	[1256]	[1423]	3	hSpCas9	negative selection	603436
88136669	88136692	12	-	26472758	K562	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-1.3198447803868731	[691]	[233]	-6	hSpCas9	negative selection	603437
88080310	88080333	12	-	26627737	DLD1	viability	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.27996772451852003	[590]	[154,231,277]	3	hSpCas9	negative selection	785767
88086450	88086473	12	-	26627737	DLD1	viability	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-0.025366618930314555	[108]	[23,78,3]	0	hSpCas9	negative selection	785768
88089211	88089234	12	-	26627737	DLD1	viability	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	-0.017807457414157346	[1011]	[395,291,256]	0	hSpCas9	negative selection	785769
88096900	88096923	12	-	26627737	DLD1	viability	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.5183287342098708	[323]	[66,66,76]	-5	hSpCas9	negative selection	785770
88111735	88111758	12	-	26627737	DLD1	viability	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.6827782976922554	[620]	[242,330,354]	6	hSpCas9	negative selection	785771
88118503	88118526	12	-	26627737	DLD1	viability	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.6356164383665825	[1302]	[564,909,461]	6	hSpCas9	negative selection	785772
88080310	88080333	12	-	26627737	GBM cells	viability after 5 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.3567644577035024	[414]	[278,290]	5	hSpCas9	negative selection	868082
88086450	88086473	12	-	26627737	GBM cells	viability after 5 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-0.48500110689737785	[106]	[44,36]	-6	hSpCas9	negative selection	868083
88089211	88089234	12	-	26627737	GBM cells	viability after 5 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.1051441399142864	[435]	[210,291]	1	hSpCas9	negative selection	868084
88096900	88096923	12	-	26627737	GBM cells	viability after 5 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.3487292235661679	[316]	[123,142]	-5	hSpCas9	negative selection	868085
88111735	88111758	12	-	26627737	GBM cells	viability after 5 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.17775460467689097	[468]	[258,309]	3	hSpCas9	negative selection	868086
88118503	88118526	12	-	26627737	GBM cells	viability after 5 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.3662884115910985	[987]	[660,704]	5	hSpCas9	negative selection	868087
88080310	88080333	12	-	26627737	GBM cells	viability after 13 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.3497098289862043	[414]	[292,281]	4	hSpCas9	negative selection	950397
88086450	88086473	12	-	26627737	GBM cells	viability after 13 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-0.4147143332780403	[106]	[42,43]	-5	hSpCas9	negative selection	950398
88089211	88089234	12	-	26627737	GBM cells	viability after 13 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.5249312312869411	[435]	[421,273]	6	hSpCas9	negative selection	950399
88096900	88096923	12	-	26627737	GBM cells	viability after 13 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.9887897946314563	[316]	[116,61]	-8	hSpCas9	negative selection	950400
88111735	88111758	12	-	26627737	GBM cells	viability after 13 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.11345045024749445	[468]	[298,255]	1	hSpCas9	negative selection	950401
88118503	88118526	12	-	26627737	GBM cells	viability after 13 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.39985734972658404	[987]	[773,652]	5	hSpCas9	negative selection	950402
88080310	88080333	12	-	26627737	GBM cells	viability after 21 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.8948753935878263	[414]	[401,434]	8	hSpCas9	negative selection	1032712
88086450	88086473	12	-	26627737	GBM cells	viability after 21 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	0.06318296140804369	[106]	[66,54]	0	hSpCas9	negative selection	1032713
88089211	88089234	12	-	26627737	GBM cells	viability after 21 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.1342934753288927	[435]	[283,237]	1	hSpCas9	negative selection	1032714
88096900	88096923	12	-	26627737	GBM cells	viability after 21 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.5052735910462087	[316]	[136,106]	-4	hSpCas9	negative selection	1032715
88111735	88111758	12	-	26627737	GBM cells	viability after 21 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	-0.1575814368469376	[468]	[229,226]	-1	hSpCas9	negative selection	1032716
88118503	88118526	12	-	26627737	GBM cells	viability after 21 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.6005541107856409	[987]	[792,832]	6	hSpCas9	negative selection	1032717
88080310	88080333	12	-	26627737	RPE1	viability after 9 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.9653822885292082	[778]	[356,629]	6	hSpCas9	negative selection	1115027
88086450	88086473	12	-	26627737	RPE1	viability after 9 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-3.100420414667778	[119]	[6,0]	-9	hSpCas9	negative selection	1115028
88089211	88089234	12	-	26627737	RPE1	viability after 9 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	-0.10589854376793162	[1734]	[433,595]	0	hSpCas9	negative selection	1115029
88096900	88096923	12	-	26627737	RPE1	viability after 9 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.6812994243479134	[670]	[130,130]	-5	hSpCas9	negative selection	1115030
88111735	88111758	12	-	26627737	RPE1	viability after 9 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	-0.4135435546517052	[2475]	[536,639]	-3	hSpCas9	negative selection	1115031
88118503	88118526	12	-	26627737	RPE1	viability after 9 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.4986679525705713	[3063]	[1329,1387]	3	hSpCas9	negative selection	1115032
88080310	88080333	12	-	26627737	RPE1	viability after 12 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	1.0035027613013738	[778]	[303,541]	6	hSpCas9	negative selection	1197342
88086450	88086473	12	-	26627737	RPE1	viability after 12 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-2.9801908641019574	[119]	[6,0]	-9	hSpCas9	negative selection	1197343
88089211	88089234	12	-	26627737	RPE1	viability after 12 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.15442613357185175	[1734]	[443,597]	1	hSpCas9	negative selection	1197344
88096900	88096923	12	-	26627737	RPE1	viability after 12 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.921600922797661	[670]	[134,52]	-6	hSpCas9	negative selection	1197345
88111735	88111758	12	-	26627737	RPE1	viability after 12 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	-0.30852216303373114	[2475]	[558,513]	-2	hSpCas9	negative selection	1197346
88118503	88118526	12	-	26627737	RPE1	viability after 12 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.6771677902947879	[3063]	[1427,1197]	4	hSpCas9	negative selection	1197347
88080310	88080333	12	-	26627737	RPE1	viability after 15 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	1.254263451028481	[778]	[403,642]	7	hSpCas9	negative selection	1279657
88086450	88086473	12	-	26627737	RPE1	viability after 15 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-1.649645866416428	[119]	[20,0]	-7	hSpCas9	negative selection	1279658
88089211	88089234	12	-	26627737	RPE1	viability after 15 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	-0.3646729431832392	[1734]	[258,498]	-2	hSpCas9	negative selection	1279659
88096900	88096923	12	-	26627737	RPE1	viability after 15 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.16924125389429542	[670]	[179,157]	-1	hSpCas9	negative selection	1279660
88111735	88111758	12	-	26627737	RPE1	viability after 15 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	-0.7137404477655626	[2475]	[310,538]	-4	hSpCas9	negative selection	1279661
88118503	88118526	12	-	26627737	RPE1	viability after 15 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.8205915163943558	[3063]	[2077,1002]	5	hSpCas9	negative selection	1279662
88080310	88080333	12	-	26627737	RPE1	viability after 18 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	1.1112491917550225	[778]	[283,635]	6	hSpCas9	negative selection	1361972
88086450	88086473	12	-	26627737	RPE1	viability after 18 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-1.8881346865691873	[119]	[15,0]	-8	hSpCas9	negative selection	1361973
88089211	88089234	12	-	26627737	RPE1	viability after 18 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	-0.1448900367199808	[1734]	[320,532]	-1	hSpCas9	negative selection	1361974
88096900	88096923	12	-	26627737	RPE1	viability after 18 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.3104888228799124	[670]	[131,160]	-2	hSpCas9	negative selection	1361975
88111735	88111758	12	-	26627737	RPE1	viability after 18 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	-0.5787272886841415	[2475]	[385,512]	-4	hSpCas9	negative selection	1361976
88118503	88118526	12	-	26627737	RPE1	viability after 18 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.5447426435162217	[3063]	[1299,1105]	3	hSpCas9	negative selection	1361977
88080310	88080333	12	-	26627737	HeLa	viability after 8 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.06287081036819098	[747]	[337,348,332]	0	hSpCas9	negative selection	1444287
88086450	88086473	12	-	26627737	HeLa	viability after 8 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-1.781701255712651	[247]	[10,66,12]	-9	hSpCas9	negative selection	1444288
88089211	88089234	12	-	26627737	HeLa	viability after 8 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.219063292644191	[731]	[539,349,266]	2	hSpCas9	negative selection	1444289
88096900	88096923	12	-	26627737	HeLa	viability after 8 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.1350301550436134	[353]	[243,108,93]	-1	hSpCas9	negative selection	1444290
88111735	88111758	12	-	26627737	HeLa	viability after 8 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.7028977175137023	[434]	[520,168,282]	6	hSpCas9	negative selection	1444291
88118503	88118526	12	-	26627737	HeLa	viability after 8 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.5351702639946814	[1209]	[792,627,866]	5	hSpCas9	negative selection	1444292
88080310	88080333	12	-	26627737	HeLa	viability after 12 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	-0.18693596279462688	[747]	[178,242,392]	-2	hSpCas9	negative selection	1526602
88086450	88086473	12	-	26627737	HeLa	viability after 12 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-2.492729460378733	[247]	[24,25,2]	-9	hSpCas9	negative selection	1526603
88089211	88089234	12	-	26627737	HeLa	viability after 12 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.6312010682147534	[731]	[377,477,545]	5	hSpCas9	negative selection	1526604
88096900	88096923	12	-	26627737	HeLa	viability after 12 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.22406769333282175	[353]	[112,128,132]	-2	hSpCas9	negative selection	1526605
88111735	88111758	12	-	26627737	HeLa	viability after 12 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	1.1129114160012283	[434]	[593,250,341]	7	hSpCas9	negative selection	1526606
88118503	88118526	12	-	26627737	HeLa	viability after 12 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.27728862199873183	[1209]	[599,519,706]	2	hSpCas9	negative selection	1526607
88080310	88080333	12	-	26627737	HeLa	viability after 15 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	-0.2900580489565807	[747]	[253,220,273]	-2	hSpCas9	negative selection	1608917
88086450	88086473	12	-	26627737	HeLa	viability after 15 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-3.9695461256224385	[247]	[5,10,1]	-9	hSpCas9	negative selection	1608918
88089211	88089234	12	-	26627737	HeLa	viability after 15 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.297845850446398	[731]	[222,557,315]	2	hSpCas9	negative selection	1608919
88096900	88096923	12	-	26627737	HeLa	viability after 15 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	0.437578710729739	[353]	[169,218,196]	3	hSpCas9	negative selection	1608920
88111735	88111758	12	-	26627737	HeLa	viability after 15 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.14138603252834442	[434]	[213,148,224]	1	hSpCas9	negative selection	1608921
88118503	88118526	12	-	26627737	HeLa	viability after 15 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.6693589985262303	[1209]	[797,768,782]	5	hSpCas9	negative selection	1608922
88080310	88080333	12	-	26627737	HeLa	viability after 18 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	-0.23863368588028422	[747]	[179,192,273]	-2	hSpCas9	negative selection	1691232
88086450	88086473	12	-	26627737	HeLa	viability after 18 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-3.8708545696417676	[247]	[4,8,1]	-9	hSpCas9	negative selection	1691233
88089211	88089234	12	-	26627737	HeLa	viability after 18 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.3297698715480982	[731]	[155,473,315]	2	hSpCas9	negative selection	1691234
88096900	88096923	12	-	26627737	HeLa	viability after 18 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	0.38835653356678546	[353]	[107,172,196]	3	hSpCas9	negative selection	1691235
88111735	88111758	12	-	26627737	HeLa	viability after 18 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.13877219160892784	[434]	[143,121,224]	1	hSpCas9	negative selection	1691236
88118503	88118526	12	-	26627737	HeLa	viability after 18 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.6668635546939388	[1209]	[530,638,782]	5	hSpCas9	negative selection	1691237
88080310	88080333	12	-	26627737	HCT116	viability after 6 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	-1.036367933430462	[1170]	[101,82]	-5	hSpCas9	negative selection	1773547
88086450	88086473	12	-	26627737	HCT116	viability after 6 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	2.5235708013381046	[145]	[140,126]	9	hSpCas9	negative selection	1773548
88089211	88089234	12	-	26627737	HCT116	viability after 6 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	-0.5163734548697929	[1799]	[260,162]	-3	hSpCas9	negative selection	1773549
88096900	88096923	12	-	26627737	HCT116	viability after 6 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.8138496551321517	[482]	[77,23]	-5	hSpCas9	negative selection	1773550
88111735	88111758	12	-	26627737	HCT116	viability after 6 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.3362578083231762	[1083]	[160,244]	2	hSpCas9	negative selection	1773551
88118503	88118526	12	-	26627737	HCT116	viability after 6 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.2037050042831936	[2097]	[413,360]	1	hSpCas9	negative selection	1773552
88080310	88080333	12	-	26627737	HCT116	viability after 8 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.3847914724777307	[404]	[289,282,300]	4	hSpCas9	negative selection	1855862
88086450	88086473	12	-	26627737	HCT116	viability after 8 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	0.19713350106373584	[91]	[47,53,71]	2	hSpCas9	negative selection	1855863
88089211	88089234	12	-	26627737	HCT116	viability after 8 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.29188604325930523	[425]	[284,282,293]	3	hSpCas9	negative selection	1855864
88096900	88096923	12	-	26627737	HCT116	viability after 8 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	0.4468641575010065	[205]	[171,97,193]	4	hSpCas9	negative selection	1855865
88111735	88111758	12	-	26627737	HCT116	viability after 8 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	-0.18914424792749052	[781]	[471,322,340]	-2	hSpCas9	negative selection	1855866
88118503	88118526	12	-	26627737	HCT116	viability after 8 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.1329879324140235	[1111]	[610,678,723]	1	hSpCas9	negative selection	1855867
88080310	88080333	12	-	26627737	HCT116	viability after 9 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	-0.44191574478550644	[1170]	[361,125]	-3	hSpCas9	negative selection	1938177
88086450	88086473	12	-	26627737	HCT116	viability after 9 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	0.6135828011241153	[145]	[124,7]	4	hSpCas9	negative selection	1938178
88089211	88089234	12	-	26627737	HCT116	viability after 9 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	-0.5730389180669128	[1799]	[307,334]	-4	hSpCas9	negative selection	1938179
88096900	88096923	12	-	26627737	HCT116	viability after 9 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.2761189285815196	[482]	[177,49]	-2	hSpCas9	negative selection	1938180
88111735	88111758	12	-	26627737	HCT116	viability after 9 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.010438053541618308	[1083]	[519,110]	0	hSpCas9	negative selection	1938181
88118503	88118526	12	-	26627737	HCT116	viability after 9 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	-0.201977813321373	[2097]	[586,407]	-1	hSpCas9	negative selection	1938182
88080310	88080333	12	-	26627737	HCT116	viability after 12 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.15397217138691677	[404]	[181,267,265]	1	hSpCas9	negative selection	2020492
88086450	88086473	12	-	26627737	HCT116	viability after 12 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	0.18129348163249315	[91]	[30,72,62]	2	hSpCas9	negative selection	2020493
88089211	88089234	12	-	26627737	HCT116	viability after 12 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.8681685065927659	[425]	[363,372,491]	7	hSpCas9	negative selection	2020494
88096900	88096923	12	-	26627737	HCT116	viability after 12 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	0.8627268861361634	[205]	[163,176,251]	7	hSpCas9	negative selection	2020495
88111735	88111758	12	-	26627737	HCT116	viability after 12 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	-0.3229298458094083	[781]	[401,403,174]	-3	hSpCas9	negative selection	2020496
88118503	88118526	12	-	26627737	HCT116	viability after 12 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	-0.1438094079933132	[1111]	[552,581,450]	-1	hSpCas9	negative selection	2020497
88080310	88080333	12	-	26627737	HCT116	viability after 15 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.21101817456442662	[404]	[359,212,245]	2	hSpCas9	negative selection	2102807
88086450	88086473	12	-	26627737	HCT116	viability after 15 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-1.040061915564081	[91]	[48,11,18]	-8	hSpCas9	negative selection	2102808
88089211	88089234	12	-	26627737	HCT116	viability after 15 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.19940763064770084	[425]	[347,229,272]	2	hSpCas9	negative selection	2102809
88096900	88096923	12	-	26627737	HCT116	viability after 15 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	0.4371803923143437	[205]	[230,84,172]	4	hSpCas9	negative selection	2102810
88111735	88111758	12	-	26627737	HCT116	viability after 15 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	-0.00822140421360018	[781]	[470,456,414]	0	hSpCas9	negative selection	2102811
88118503	88118526	12	-	26627737	HCT116	viability after 15 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.0067167918263315585	[1111]	[840,627,481]	0	hSpCas9	negative selection	2102812
88080310	88080333	12	-	26627737	HCT116	viability after 18 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.007149577915776972	[404]	[215,182,191]	0	hSpCas9	negative selection	2185122
88086450	88086473	12	-	26627737	HCT116	viability after 18 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-0.7779363406084425	[91]	[21,25,29]	-6	hSpCas9	negative selection	2185123
88089211	88089234	12	-	26627737	HCT116	viability after 18 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.5469486717753799	[425]	[410,192,305]	4	hSpCas9	negative selection	2185124
88096900	88096923	12	-	26627737	HCT116	viability after 18 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	0.8476470294719001	[205]	[204,199,128]	6	hSpCas9	negative selection	2185125
88111735	88111758	12	-	26627737	HCT116	viability after 18 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.09048395413721977	[781]	[361,526,305]	0	hSpCas9	negative selection	2185126
88118503	88118526	12	-	26627737	HCT116	viability after 18 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	-0.07245574787352371	[1111]	[696,595,221]	0	hSpCas9	negative selection	2185127
88136764	88136787	12	-	24336569	HL60	viability	ATGGCTCAGCAGTCTGCAGGTGG	CEP290	ENSG00000198707	0.08585204831065774	[491]	[1104]	0	hSpCas9	negative selection	2257322
88139534	88139557	12	-	24336569	HL60	viability	TCAAGAAGTGGAGCTGGCTTTGG	CEP290	ENSG00000198707	-0.03784441633165492	[846]	[1745]	0	hSpCas9	negative selection	2257323
88139540	88139563	12	-	24336569	HL60	viability	GAAAGCTCAAGAAGTGGAGCTGG	CEP290	ENSG00000198707	-0.28849918342558084	[474]	[822]	-3	hSpCas9	negative selection	2257324
88139546	88139569	12	-	24336569	HL60	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.23439799355911206	[142]	[355]	2	hSpCas9	negative selection	2257325
88140955	88140978	12	-	24336569	HL60	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.05931319616940545	[613]	[1246]	0	hSpCas9	negative selection	2257326
88141194	88141217	12	+	24336569	HL60	viability	CCAATTAAGCACCTTGGATAAGG	CEP290	ENSG00000198707	0.4296699882340907	[293]	[837]	4	hSpCas9	negative selection	2257327
88141205	88141228	12	-	24336569	HL60	viability	TTTATTGATTTCCTTATCCAAGG	CEP290	ENSG00000198707	-0.13454115291785795	[262]	[506]	-1	hSpCas9	negative selection	2257328
88141229	88141252	12	+	24336569	HL60	viability	TATCTGCCAGTTCTTCTTGACGG	CEP290	ENSG00000198707	1.0801456326014123	[231]	[1037]	8	hSpCas9	negative selection	2257329
88141279	88141302	12	+	24336569	HL60	viability	ATTTCTTTCCAGTTTATATTAGG	CEP290	ENSG00000198707	0.1555750966719529	[83]	[197]	1	hSpCas9	negative selection	2257330
88141287	88141310	12	-	24336569	HL60	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.3496602115784688	[335]	[557]	-3	hSpCas9	negative selection	2257331
88136764	88136787	12	-	24336569	KBM7	viability	ATGGCTCAGCAGTCTGCAGGTGG	CEP290	ENSG00000198707	-0.5029559535852559	[477]	[919]	-4	hSpCas9	negative selection	2324499
88139534	88139557	12	-	24336569	KBM7	viability	TCAAGAAGTGGAGCTGGCTTTGG	CEP290	ENSG00000198707	0.4320577897261991	[683]	[2516]	4	hSpCas9	negative selection	2324500
88139540	88139563	12	-	24336569	KBM7	viability	GAAAGCTCAAGAAGTGGAGCTGG	CEP290	ENSG00000198707	-0.627660813027366	[293]	[518]	-5	hSpCas9	negative selection	2324501
88139546	88139569	12	-	24336569	KBM7	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.2718519090400364	[192]	[435]	-2	hSpCas9	negative selection	2324502
88140955	88140978	12	-	24336569	KBM7	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	1.5106006277564905	[279]	[2175]	9	hSpCas9	negative selection	2324503
88141194	88141217	12	+	24336569	KBM7	viability	CCAATTAAGCACCTTGGATAAGG	CEP290	ENSG00000198707	-0.990477637703495	[506]	[695]	-6	hSpCas9	negative selection	2324504
88141205	88141228	12	-	24336569	KBM7	viability	TTTATTGATTTCCTTATCCAAGG	CEP290	ENSG00000198707	0.6129623453861681	[104]	[437]	5	hSpCas9	negative selection	2324505
88141229	88141252	12	+	24336569	KBM7	viability	TATCTGCCAGTTCTTCTTGACGG	CEP290	ENSG00000198707	0.23204649981883596	[289]	[928]	2	hSpCas9	negative selection	2324506
88141279	88141302	12	+	24336569	KBM7	viability	ATTTCTTTCCAGTTTATATTAGG	CEP290	ENSG00000198707	1.5232744577916009	[99]	[783]	9	hSpCas9	negative selection	2324507
88141287	88141310	12	-	24336569	KBM7	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	1.32270647081735	[106]	[729]	9	hSpCas9	negative selection	2324508
88096306	88096329	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATTCCAGCACTTGGG	CEP290	ENSG00000198707	1.9829372138366936	[192,253]	[363,12]	7	dCas9-VP64	positive selection	2430075
88101219	88101242	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CATCTGTAATCCCAGCACTTTAG	CEP290	ENSG00000198707	0.936948372456865	[294,1308]	[29,678]	4	dCas9-VP64	positive selection	2456726
88142161	88142184	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGTCCCAGAGCTCGGTGTTCAGG	CEP290	ENSG00000198707	0.8737015564090644	[203,188]	[116,37]	3	dCas9-VP64	positive selection	2473127
88142111	88142134	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACCCACGGTCGTGAACTGTAGG	CEP290	ENSG00000198707	0.45432156926071543	[29,34]	[3,15]	2	dCas9-VP64	positive selection	2473128
88142138	88142161	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTACGTTTAGATTCTCCGCCGG	CEP290	ENSG00000198707	-0.8952180000854131	[396,95]	[44,10]	-5	dCas9-VP64	positive selection	2473129
88096306	88096329	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATTCCAGCACTTGGG	CEP290	ENSG00000198707	2.0349420860207257	[143,154]	[35,352]	8	dCas9-VP64	positive selection	2525330
88101219	88101242	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CATCTGTAATCCCAGCACTTTAG	CEP290	ENSG00000198707	-0.19682723409902197	[171,197]	[36,65]	-2	dCas9-VP64	positive selection	2551981
88142161	88142184	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGTCCCAGAGCTCGGTGTTCAGG	CEP290	ENSG00000198707	1.0528017262896692	[67,51]	[46,34]	6	dCas9-VP64	positive selection	2568382
88142111	88142134	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACCCACGGTCGTGAACTGTAGG	CEP290	ENSG00000198707	0.6695674389914615	[145,81]	[74,44]	5	dCas9-VP64	positive selection	2568383
88142138	88142161	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTACGTTTAGATTCTCCGCCGG	CEP290	ENSG00000198707	-0.02334427018408758	[222,51]	[73,15]	0	dCas9-VP64	positive selection	2568384
88121136	88121159	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATATGAGTCTGTTGAGAAAGGG	CEP290	ENSG00000198707	-0.06703898316085966	[4,4]	[5,2]	-1	hSpCas9	positive selection	2978637
88126375	88126398	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAATGTTACATAACCTAAGGG	CEP290	ENSG00000198707	0.24204094597068151	[2,2]	[2,3]	5	hSpCas9	positive selection	2978638
88131197	88131220	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.2495739129264678	[5,5]	[5,4]	5	hSpCas9	positive selection	2978639
88141232	88141255	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGCCAGTTCTTCTTGACGGGG	CEP290	ENSG00000198707	0.23153597039509152	[3,3]	[3,3]	5	hSpCas9	positive selection	2978640
88121136	88121159	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATATGAGTCTGTTGAGAAAGGG	CEP290	ENSG00000198707	-0.17141820224675708	[4,4]	[3,1]	-2	hSpCas9	positive selection	3046495
88126375	88126398	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAATGTTACATAACCTAAGGG	CEP290	ENSG00000198707	-0.44503461480580897	[2,2]	[2,0]	-6	hSpCas9	positive selection	3046496
88131197	88131220	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.25021566321270583	[5,5]	[4,3]	4	hSpCas9	positive selection	3046497
88141232	88141255	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGCCAGTTCTTCTTGACGGGG	CEP290	ENSG00000198707	-0.20481323182854483	[3,3]	[4,0]	-3	hSpCas9	positive selection	3046498
88140955	88140978		-	24336571	A375	resistance to PLX after 7 days	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.2891761709458913	[4,4]	[5,5]	7	hSpCas9	positive selection	3105032
88141287	88141310		-	24336571	A375	resistance to PLX after 7 days	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.16467865493488976	[3,3]	[2,2]	-5	hSpCas9	positive selection	3105033
88141235	88141258		-	24336571	A375	resistance to PLX after 7 days	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	-0.06215442515679359	[3,4]	[4,3]	-2	hSpCas9	positive selection	3105035
88140964	88140987		+	24336571	A375	resistance to PLX after 7 days	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.31928373750299666	[9,7]	[6,6]	-8	hSpCas9	positive selection	3105036
88140955	88140978		-	24336571	A375	resistance to PLX after 14 days	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.20007733728331145	[3,8]	[2,3]	2	hSpCas9	positive selection	3162825
88141287	88141310		-	24336571	A375	resistance to PLX after 14 days	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	0.14092403486312555	[5,3]	[2,1]	1	hSpCas9	positive selection	3162826
88141235	88141258		-	24336571	A375	resistance to PLX after 14 days	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	-0.22860512137233346	[4,5]	[1,1]	-2	hSpCas9	positive selection	3162828
88140964	88140987		+	24336571	A375	resistance to PLX after 14 days	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	0.423580278208938	[7,7]	[4,4]	4	hSpCas9	positive selection	3162829
88140955	88140978		-	24336571	A375	viability after 7 days	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.8916491751249235	[9]	[4,4]	-8	hSpCas9	negative selection	3220618
88141287	88141310		-	24336571	A375	viability after 7 days	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.7346587512167227	[6]	[3,3]	-8	hSpCas9	negative selection	3220619
88141235	88141258		-	24336571	A375	viability after 7 days	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	-0.4388591712027139	[6]	[3,4]	-6	hSpCas9	negative selection	3220621
88140964	88140987		+	24336571	A375	viability after 7 days	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.18307847225245122	[10]	[9,7]	-3	hSpCas9	negative selection	3220622
88140955	88140978		-	24336571	A375	viability after 14 days	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.5038878724975628	[9]	[3,8]	-6	hSpCas9	negative selection	3278411
88141287	88141310		-	24336571	A375	viability after 14 days	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.28439132183580773	[6]	[5,3]	-3	hSpCas9	negative selection	3278412
88141235	88141258		-	24336571	A375	viability after 14 days	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	-0.13226336760182633	[6]	[4,5]	-1	hSpCas9	negative selection	3278414
88140964	88140987		+	24336571	A375	viability after 14 days	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.35389896888473504	[10]	[7,7]	-4	hSpCas9	negative selection	3278415
88141235	88141258	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	-0.4629683508930926	[192,228]	[0,0]	-3	hSpCas9	positive selection	3342731
88141287	88141310	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	3.868155343983939	[6,13]	[0,0]	9	hSpCas9	positive selection	3342732
88139546	88139569	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	1.3401004069025453	[49,70]	[0,0]	6	hSpCas9	positive selection	3342733
88140955	88140978	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.6723637107246789	[95,95]	[0,0]	3	hSpCas9	positive selection	3361966
88140964	88140987	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	0.38696149186243056	[116,116]	[0,0]	2	hSpCas9	positive selection	3361967
88139515	88139538	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.8479352753081334	[84,84]	[0,0]	4	hSpCas9	positive selection	3361968
88121135	88121158	12	+	26780180	HT29	viability (Avana library 4 designs)	CATATGAGTCTGTTGAGAAAGGG	CEP290	ENSG00000198707	1.03422113706757	[]	[]	4	hSpCas9	negative selection	3414975
88126375	88126398	12	-	26780180	HT29	viability (Avana library 4 designs)	GCAAATGTTACATAACCTAAGGG	CEP290	ENSG00000198707	1.05479327348178	[]	[]	4	hSpCas9	negative selection	3414976
88131197	88131220	12	-	26780180	HT29	viability (Avana library 4 designs)	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.183748704731266	[]	[]	0	hSpCas9	negative selection	3414977
88141231	88141254	12	+	26780180	HT29	viability (Avana library 4 designs)	TCTGCCAGTTCTTCTTGACGGGG	CEP290	ENSG00000198707	1.24936851428067	[]	[]	5	hSpCas9	negative selection	3414978
88126375	88126398	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAATGTTACATAACCTAAGGG	CEP290	ENSG00000198707	-14.067082733054	[]	[]	-8	hSpCas9	negative selection	3491751
88131197	88131220	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	-1.2818427105089	[]	[]	-1	hSpCas9	negative selection	3491752
88141231	88141254	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGCCAGTTCTTCTTGACGGGG	CEP290	ENSG00000198707	3.17329830429011	[]	[]	5	hSpCas9	negative selection	3491753
88121135	88121158	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATATGAGTCTGTTGAGAAAGGG	CEP290	ENSG00000198707	-2.04311373452252	[]	[]	-2	hSpCas9	negative selection	3491754
88125245	88125268	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATGAGCTCCAAAGAAACAAAGG	CEP290	ENSG00000198707	-2.66474061069639	[]	[]	-3	hSpCas9	negative selection	3491755
88121089	88121112	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTAAAAGAGAAAACTAAAGAGG	CEP290	ENSG00000198707	-20.7205992726654	[]	[]	-9	hSpCas9	negative selection	3491756
88126375	88126398	12	-	26780180	A375	viability (Avana lentiGuide)	GCAAATGTTACATAACCTAAGGG	CEP290	ENSG00000198707	2.56340293280139	[]	[]	2	hSpCas9	negative selection	3600410
88131197	88131220	12	-	26780180	A375	viability (Avana lentiGuide)	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	4.01241506178679	[]	[]	4	hSpCas9	negative selection	3600411
88141231	88141254	12	+	26780180	A375	viability (Avana lentiGuide)	TCTGCCAGTTCTTCTTGACGGGG	CEP290	ENSG00000198707	5.23418039499287	[]	[]	4	hSpCas9	negative selection	3600412
88121135	88121158	12	+	26780180	A375	viability (Avana lentiGuide)	CATATGAGTCTGTTGAGAAAGGG	CEP290	ENSG00000198707	-3.6179114180709	[]	[]	-6	hSpCas9	negative selection	3600413
88125245	88125268	12	-	26780180	A375	viability (Avana lentiGuide)	AATGAGCTCCAAAGAAACAAAGG	CEP290	ENSG00000198707	-2.81412984675957	[]	[]	-5	hSpCas9	negative selection	3600414
88121089	88121112	12	-	26780180	A375	viability (Avana lentiGuide)	TTTAAAAGAGAAAACTAAAGAGG	CEP290	ENSG00000198707	-6.05866241816238	[]	[]	-8	hSpCas9	negative selection	3600415
88126375	88126398	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAATGTTACATAACCTAAGGG	CEP290	ENSG00000198707	-0.9484670641462543	[6]	[4,1]	-8	hSpCas9	positive selection	3709069
88131197	88131220	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	-0.10680131438144913	[6]	[5,4]	-2	hSpCas9	positive selection	3709070
88141231	88141254	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGCCAGTTCTTCTTGACGGGG	CEP290	ENSG00000198707	0.21932749191490325	[4]	[5,5]	6	hSpCas9	positive selection	3709071
88121135	88121158	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATATGAGTCTGTTGAGAAAGGG	CEP290	ENSG00000198707	-0.033221816538086285	[6]	[5,5]	0	hSpCas9	positive selection	3709072
88125245	88125268	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGAGCTCCAAAGAAACAAAGG	CEP290	ENSG00000198707	-0.3804854880784872	[5]	[3,3]	-5	hSpCas9	positive selection	3709073
88121089	88121112	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTAAAAGAGAAAACTAAAGAGG	CEP290	ENSG00000198707	-1.311598755745413	[9]	[4,1]	-9	hSpCas9	positive selection	3709074
88126375	88126398	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAATGTTACATAACCTAAGGG	CEP290	ENSG00000198707	0.18556244345504191	[4]	[4,3]	4	hSpCas9	positive selection	3817676
88131197	88131220	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	-0.18752225636137707	[7]	[4,5]	-3	hSpCas9	positive selection	3817677
88141231	88141254	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGCCAGTTCTTCTTGACGGGG	CEP290	ENSG00000198707	-0.7254643442557183	[5]	[0,4]	-7	hSpCas9	positive selection	3817678
88121135	88121158	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATATGAGTCTGTTGAGAAAGGG	CEP290	ENSG00000198707	0.23667040153585214	[5]	[5,6]	6	hSpCas9	positive selection	3817679
88125245	88125268	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGAGCTCCAAAGAAACAAAGG	CEP290	ENSG00000198707	0.06531181265537685	[4]	[4,4]	1	hSpCas9	positive selection	3817680
88121089	88121112	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTAAAAGAGAAAACTAAAGAGG	CEP290	ENSG00000198707	0.25328424151592327	[4]	[2,5]	6	hSpCas9	positive selection	3817681
88140955	88140978	12	-	26780180	A375	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	1.03158562002946	[]	[]	5	hSpCas9	negative selection	3925836
88141287	88141310	12	-	26780180	A375	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	0.837421348415612	[]	[]	3	hSpCas9	negative selection	3925837
88141235	88141258	12	-	26780180	A375	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	1.42107206267259	[]	[]	7	hSpCas9	negative selection	3925838
88140964	88140987	12	+	26780180	A375	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	1.51846756735653	[]	[]	8	hSpCas9	negative selection	3925839
88139546	88139569	12	-	26780180	A375	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	1.07949791329254	[]	[]	5	hSpCas9	negative selection	3925840
88139515	88139538	12	-	26780180	A375	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	1.08741674691411	[]	[]	5	hSpCas9	negative selection	3925841
88140955	88140978	12	-	26780180	HT29	viability (GeCKOv2 library)	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.742652999023323	[]	[]	3	hSpCas9	negative selection	4033802
88141287	88141310	12	-	26780180	HT29	viability (GeCKOv2 library)	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	1.45859426397773	[]	[]	7	hSpCas9	negative selection	4033803
88141235	88141258	12	-	26780180	HT29	viability (GeCKOv2 library)	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.870869711254347	[]	[]	3	hSpCas9	negative selection	4033804
88140964	88140987	12	+	26780180	HT29	viability (GeCKOv2 library)	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	2.23765005370521	[]	[]	9	hSpCas9	negative selection	4033805
88139546	88139569	12	-	26780180	HT29	viability (GeCKOv2 library)	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.877119825170655	[]	[]	3	hSpCas9	negative selection	4033806
88139515	88139538	12	-	26780180	HT29	viability (GeCKOv2 library)	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	1.34417289543963	[]	[]	6	hSpCas9	negative selection	4033807
88140955	88140978	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.14283058839217488	[2]	[1,1]	3	hSpCas9	positive selection	4127088
88141287	88141310	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	0.31482451738677963	[0]	[0,0]	7	hSpCas9	positive selection	4127089
88141235	88141258	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	-0.6799300916786012	[2]	[0,0]	-9	hSpCas9	positive selection	4127091
88140964	88140987	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.1335175899893451	[2]	[0,2]	-3	hSpCas9	positive selection	4127092
88140955	88140978	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.45220427881360475	[2]	[0,5,2,0]	3	hSpCas9	positive selection	4191110
88141287	88141310	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.6635867880282155	[3]	[0,0,1,0]	-8	hSpCas9	positive selection	4191111
88141235	88141258	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	-0.37072444593639353	[3]	[2,0,0,0]	-5	hSpCas9	positive selection	4191113
88140964	88140987	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	0.562831994548497	[2]	[4,2,1,0]	4	hSpCas9	positive selection	4191114
88141235	88141258	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	-0.07398288872724301	[3]	[2,2]	-1	hSpCas9	positive selection	4262828
88141287	88141310	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.24401352604379317	[1]	[1,0]	-5	hSpCas9	positive selection	4262829
88139546	88139569	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.09234547911825203	[2]	[1,1]	-2	hSpCas9	positive selection	4262830
88140955	88140978	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.04798339977015971	[2]	[2,1]	1	hSpCas9	positive selection	4327102
88140964	88140987	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.6070353924588892	[2]	[2,0]	-8	hSpCas9	positive selection	4327103
88139515	88139538	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	-0.16652383478850746	[1]	[1,0]	-3	hSpCas9	positive selection	4327104
88093808	88093830	12	-	27760321	OCIAML3	viability	CGGACTTCGTTAAAGCAAATGG	CEP290	ENSG00000198707	0.6869063649638844	[129,141]	[128,228]	7	hSpCas9	negative selection	4388642
88111252	88111274	12	+	27760321	OCIAML3	viability	TAGATGGTGCTATCCCATCAGG	CEP290	ENSG00000198707	-0.7718670915838705	[364,326]	[146,172]	-6	hSpCas9	negative selection	4388643
88111305	88111327	12	-	27760321	OCIAML3	viability	GTCTTTTACGACAATCAGAAGG	CEP290	ENSG00000198707	0.5917217143786759	[142,129]	[188,123]	7	hSpCas9	negative selection	4388644
88117131	88117153	12	-	27760321	OCIAML3	viability	TATATAGGATTAACCACTGAGG	CEP290	ENSG00000198707	-3.3358663881737733	[7,16]	[0,0]	-9	hSpCas9	negative selection	4388645
88131200	88131222	12	-	27760321	OCIAML3	viability	TAGTTGGCTCTTCGAAATGAGG	CEP290	ENSG00000198707	-0.24910348963587492	[423,399]	[253,293]	-3	hSpCas9	negative selection	4388646
88093808	88093830	12	-	27760321	OCIAML2	viability	CGGACTTCGTTAAAGCAAATGG	CEP290	ENSG00000198707	-0.29968339086237683	[129,141]	[89,89]	-4	hSpCas9	negative selection	4472105
88111252	88111274	12	+	27760321	OCIAML2	viability	TAGATGGTGCTATCCCATCAGG	CEP290	ENSG00000198707	-0.888919612339253	[364,326]	[134,171]	-7	hSpCas9	negative selection	4472106
88111305	88111327	12	-	27760321	OCIAML2	viability	GTCTTTTACGACAATCAGAAGG	CEP290	ENSG00000198707	0.516415433100069	[142,129]	[137,183]	7	hSpCas9	negative selection	4472107
88117131	88117153	12	-	27760321	OCIAML2	viability	TATATAGGATTAACCACTGAGG	CEP290	ENSG00000198707	-0.3324383329241565	[7,16]	[6,9]	-4	hSpCas9	negative selection	4472108
88131200	88131222	12	-	27760321	OCIAML2	viability	TAGTTGGCTCTTCGAAATGAGG	CEP290	ENSG00000198707	-0.21521339263141032	[423,399]	[213,383]	-3	hSpCas9	negative selection	4472109
88093808	88093830	12	-	27760321	MV411	viability	CGGACTTCGTTAAAGCAAATGG	CEP290	ENSG00000198707	2.601558921261847	[129,141]	[874,57]	9	hSpCas9	negative selection	4555568
88111252	88111274	12	+	27760321	MV411	viability	TAGATGGTGCTATCCCATCAGG	CEP290	ENSG00000198707	0.6266425599601435	[364,326]	[467,177]	4	hSpCas9	negative selection	4555569
88111305	88111327	12	-	27760321	MV411	viability	GTCTTTTACGACAATCAGAAGG	CEP290	ENSG00000198707	1.5053725439994683	[142,129]	[213,317]	9	hSpCas9	negative selection	4555570
88117131	88117153	12	-	27760321	MV411	viability	TATATAGGATTAACCACTGAGG	CEP290	ENSG00000198707	-3.0907878192590914	[7,16]	[0,0]	-9	hSpCas9	negative selection	4555571
88131200	88131222	12	-	27760321	MV411	viability	TAGTTGGCTCTTCGAAATGAGG	CEP290	ENSG00000198707	-0.37502693926278435	[423,399]	[246,153]	-3	hSpCas9	negative selection	4555572
88093808	88093830	12	-	27760321	HL60	viability	CGGACTTCGTTAAAGCAAATGG	CEP290	ENSG00000198707	0.36052257713461877	[129,141]	[130,156]	4	hSpCas9	negative selection	4639031
88111252	88111274	12	+	27760321	HL60	viability	TAGATGGTGCTATCCCATCAGG	CEP290	ENSG00000198707	0.12655605864917396	[364,326]	[313,301]	1	hSpCas9	negative selection	4639032
88111305	88111327	12	-	27760321	HL60	viability	GTCTTTTACGACAATCAGAAGG	CEP290	ENSG00000198707	-0.7085064261449132	[142,129]	[57,78]	-6	hSpCas9	negative selection	4639033
88117131	88117153	12	-	27760321	HL60	viability	TATATAGGATTAACCACTGAGG	CEP290	ENSG00000198707	-0.11526929362862859	[7,16]	[0,18]	-1	hSpCas9	negative selection	4639034
88131200	88131222	12	-	27760321	HL60	viability	TAGTTGGCTCTTCGAAATGAGG	CEP290	ENSG00000198707	0.05075719543643503	[423,399]	[428,263]	0	hSpCas9	negative selection	4639035
88093808	88093830	12	-	27760321	HT1080	viability	CGGACTTCGTTAAAGCAAATGG	CEP290	ENSG00000198707	-1.0394788865340874	[141,110]	[45,0]	-4	hSpCas9	negative selection	4722494
88111252	88111274	12	+	27760321	HT1080	viability	TAGATGGTGCTATCCCATCAGG	CEP290	ENSG00000198707	-1.3758950554868035	[326,254]	[5,86]	-5	hSpCas9	negative selection	4722495
88111305	88111327	12	-	27760321	HT1080	viability	GTCTTTTACGACAATCAGAAGG	CEP290	ENSG00000198707	0.04127998516216547	[129,101]	[48,45]	0	hSpCas9	negative selection	4722496
88117131	88117153	12	-	27760321	HT1080	viability	TATATAGGATTAACCACTGAGG	CEP290	ENSG00000198707	-2.57725339867981	[16,12]	[0,0]	-7	hSpCas9	negative selection	4722497
88131200	88131222	12	-	27760321	HT1080	viability	TAGTTGGCTCTTCGAAATGAGG	CEP290	ENSG00000198707	1.35872934964077	[399,311]	[409,312]	7	hSpCas9	negative selection	4722498
88093808	88093830	12	-	27760321	HT29	viability after 7 days	CGGACTTCGTTAAAGCAAATGG	CEP290	ENSG00000198707	0.24042799553715488	[141,110]	[294,171,125]	3	hSpCas9	negative selection	4805957
88111252	88111274	12	+	27760321	HT29	viability after 7 days	TAGATGGTGCTATCCCATCAGG	CEP290	ENSG00000198707	-0.11342907061344515	[326,254]	[444,223,380]	-2	hSpCas9	negative selection	4805958
88111305	88111327	12	-	27760321	HT29	viability after 7 days	GTCTTTTACGACAATCAGAAGG	CEP290	ENSG00000198707	0.14169859543868224	[129,101]	[116,117,248]	2	hSpCas9	negative selection	4805959
88117131	88117153	12	-	27760321	HT29	viability after 7 days	TATATAGGATTAACCACTGAGG	CEP290	ENSG00000198707	-3.8920748510027883	[16,12]	[1,0,0]	-9	hSpCas9	negative selection	4805960
88131200	88131222	12	-	27760321	HT29	viability after 7 days	TAGTTGGCTCTTCGAAATGAGG	CEP290	ENSG00000198707	-0.4036572990275846	[399,311]	[344,462,232]	-5	hSpCas9	negative selection	4805961
88093808	88093830	12	-	27760321	HT29	viability after 25 days	CGGACTTCGTTAAAGCAAATGG	CEP290	ENSG00000198707	0.3123177509431774	[141,110]	[226,165,137]	3	hSpCas9	negative selection	4889420
88111252	88111274	12	+	27760321	HT29	viability after 25 days	TAGATGGTGCTATCCCATCAGG	CEP290	ENSG00000198707	-0.9582336103761493	[326,254]	[151,168,195]	-6	hSpCas9	negative selection	4889421
88111305	88111327	12	-	27760321	HT29	viability after 25 days	GTCTTTTACGACAATCAGAAGG	CEP290	ENSG00000198707	0.09398343152293065	[129,101]	[60,230,136]	0	hSpCas9	negative selection	4889422
88117131	88117153	12	-	27760321	HT29	viability after 25 days	TATATAGGATTAACCACTGAGG	CEP290	ENSG00000198707	-4.096935663526334	[16,12]	[0,0,0]	-9	hSpCas9	negative selection	4889423
88131200	88131222	12	-	27760321	HT29	viability after 25 days	TAGTTGGCTCTTCGAAATGAGG	CEP290	ENSG00000198707	-0.3804312909447979	[399,311]	[202,307,446]	-4	hSpCas9	negative selection	4889424
88093808	88093830	12	-	27760321	HT29	viability after 22 days	CGGACTTCGTTAAAGCAAATGG	CEP290	ENSG00000198707	-0.12311087301285961	[141,110]	[195,91,112]	-1	hSpCas9	negative selection	4972883
88111252	88111274	12	+	27760321	HT29	viability after 22 days	TAGATGGTGCTATCCCATCAGG	CEP290	ENSG00000198707	-0.8961473517032232	[326,254]	[181,305,52]	-6	hSpCas9	negative selection	4972884
88111305	88111327	12	-	27760321	HT29	viability after 22 days	GTCTTTTACGACAATCAGAAGG	CEP290	ENSG00000198707	-0.044771143800593105	[129,101]	[157,140,89]	0	hSpCas9	negative selection	4972885
88117131	88117153	12	-	27760321	HT29	viability after 22 days	TATATAGGATTAACCACTGAGG	CEP290	ENSG00000198707	-4.114254295385593	[16,12]	[0,0,0]	-9	hSpCas9	negative selection	4972886
88131200	88131222	12	-	27760321	HT29	viability after 22 days	TAGTTGGCTCTTCGAAATGAGG	CEP290	ENSG00000198707	-0.12429942534495898	[399,311]	[265,564,303]	-1	hSpCas9	negative selection	4972887
88093808	88093830	12	-	27760321	HT29	viability after 19 days	CGGACTTCGTTAAAGCAAATGG	CEP290	ENSG00000198707	0.36423950261611915	[141,110]	[310,136,125]	3	hSpCas9	negative selection	5056346
88111252	88111274	12	+	27760321	HT29	viability after 19 days	TAGATGGTGCTATCCCATCAGG	CEP290	ENSG00000198707	-1.6742929877571313	[326,254]	[188,11,119]	-7	hSpCas9	negative selection	5056347
88111305	88111327	12	-	27760321	HT29	viability after 19 days	GTCTTTTACGACAATCAGAAGG	CEP290	ENSG00000198707	0.31358993303413274	[129,101]	[135,199,155]	3	hSpCas9	negative selection	5056348
88117131	88117153	12	-	27760321	HT29	viability after 19 days	TATATAGGATTAACCACTGAGG	CEP290	ENSG00000198707	-0.791260570690274	[16,12]	[28,0,1]	-6	hSpCas9	negative selection	5056349
88131200	88131222	12	-	27760321	HT29	viability after 19 days	TAGTTGGCTCTTCGAAATGAGG	CEP290	ENSG00000198707	-0.2779176223844616	[399,311]	[543,337,153]	-3	hSpCas9	negative selection	5056350
88093808	88093830	12	-	27760321	HT29	viability after 16 days	CGGACTTCGTTAAAGCAAATGG	CEP290	ENSG00000198707	0.010109284622518144	[141,110]	[228,94,112]	0	hSpCas9	negative selection	5139809
88111252	88111274	12	+	27760321	HT29	viability after 16 days	TAGATGGTGCTATCCCATCAGG	CEP290	ENSG00000198707	-0.5169593259812293	[326,254]	[357,105,233]	-5	hSpCas9	negative selection	5139810
88111305	88111327	12	-	27760321	HT29	viability after 16 days	GTCTTTTACGACAATCAGAAGG	CEP290	ENSG00000198707	0.3992747198916813	[129,101]	[253,149,117]	4	hSpCas9	negative selection	5139811
88117131	88117153	12	-	27760321	HT29	viability after 16 days	TATATAGGATTAACCACTGAGG	CEP290	ENSG00000198707	-2.5381210789009954	[16,12]	[5,0,1]	-8	hSpCas9	negative selection	5139812
88131200	88131222	12	-	27760321	HT29	viability after 16 days	TAGTTGGCTCTTCGAAATGAGG	CEP290	ENSG00000198707	-0.19465779039765382	[399,311]	[277,399,357]	-2	hSpCas9	negative selection	5139813
88093808	88093830	12	-	27760321	HT29	viability after 13 days	CGGACTTCGTTAAAGCAAATGG	CEP290	ENSG00000198707	-0.1968447298902405	[141,110]	[203,103,78]	-2	hSpCas9	negative selection	5223272
88111252	88111274	12	+	27760321	HT29	viability after 13 days	TAGATGGTGCTATCCCATCAGG	CEP290	ENSG00000198707	-0.19691294558233668	[326,254]	[289,290,301]	-2	hSpCas9	negative selection	5223273
88111305	88111327	12	-	27760321	HT29	viability after 13 days	GTCTTTTACGACAATCAGAAGG	CEP290	ENSG00000198707	-0.8781244217383675	[129,101]	[36,95,85]	-7	hSpCas9	negative selection	5223274
88117131	88117153	12	-	27760321	HT29	viability after 13 days	TATATAGGATTAACCACTGAGG	CEP290	ENSG00000198707	-4.119237189985596	[16,12]	[0,0,0]	-9	hSpCas9	negative selection	5223275
88131200	88131222	12	-	27760321	HT29	viability after 13 days	TAGTTGGCTCTTCGAAATGAGG	CEP290	ENSG00000198707	0.1323473302288883	[399,311]	[317,600,439]	1	hSpCas9	negative selection	5223276
88093808	88093830	12	-	27760321	HT29	viability after 10 days	CGGACTTCGTTAAAGCAAATGG	CEP290	ENSG00000198707	-0.1244265413027712	[141,110]	[202,84,144]	-2	hSpCas9	negative selection	5306735
88111252	88111274	12	+	27760321	HT29	viability after 10 days	TAGATGGTGCTATCCCATCAGG	CEP290	ENSG00000198707	-0.8171788990285291	[326,254]	[127,229,259]	-7	hSpCas9	negative selection	5306736
88111305	88111327	12	-	27760321	HT29	viability after 10 days	GTCTTTTACGACAATCAGAAGG	CEP290	ENSG00000198707	0.43218866070278605	[129,101]	[233,229,124]	6	hSpCas9	negative selection	5306737
88117131	88117153	12	-	27760321	HT29	viability after 10 days	TATATAGGATTAACCACTGAGG	CEP290	ENSG00000198707	-3.809564558040372	[16,12]	[1,0,0]	-9	hSpCas9	negative selection	5306738
88131200	88131222	12	-	27760321	HT29	viability after 10 days	TAGTTGGCTCTTCGAAATGAGG	CEP290	ENSG00000198707	-0.3274308426438595	[399,311]	[345,465,255]	-4	hSpCas9	negative selection	5306739
88093808	88093830	12	-	27760321	MOLM13	viability	CGGACTTCGTTAAAGCAAATGG	CEP290	ENSG00000198707	2.2546274369571444	[129,141]	[587,181]	9	hSpCas9	negative selection	5390198
88111252	88111274	12	+	27760321	MOLM13	viability	TAGATGGTGCTATCCCATCAGG	CEP290	ENSG00000198707	0.4825925993497247	[364,326]	[454,116]	3	hSpCas9	negative selection	5390199
88111305	88111327	12	-	27760321	MOLM13	viability	GTCTTTTACGACAATCAGAAGG	CEP290	ENSG00000198707	1.566719230203228	[142,129]	[254,204]	9	hSpCas9	negative selection	5390200
88117131	88117153	12	-	27760321	MOLM13	viability	TATATAGGATTAACCACTGAGG	CEP290	ENSG00000198707	-2.864731006431496	[7,16]	[0,0]	-8	hSpCas9	negative selection	5390201
88131200	88131222	12	-	27760321	MOLM13	viability	TAGTTGGCTCTTCGAAATGAGG	CEP290	ENSG00000198707	0.6739404956295743	[423,399]	[287,441]	4	hSpCas9	negative selection	5390202
88141999	88142022	12	+	27661255	K562	viability	GGACTCTGGGTCCAGCCAAATGG	CEP290	ENSG00000198707	-0.026831747763224834	[1302,1309]	[1141,923]	-1	dCas9-KRAB	negative selection	5470336
88141235	88141258	12	-	27260156	BXPC3	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.3914409388827373	[587]	[685,773,856,934]	8	hSpCas9	negative selection	5535288
88141287	88141310	12	-	27260156	BXPC3	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.005539962361764905	[194]	[177,160,246,234]	0	hSpCas9	negative selection	5535289
88139546	88139569	12	-	27260156	BXPC3	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.20360192174983083	[275]	[336,393,268,319]	4	hSpCas9	negative selection	5535290
88140955	88140978	12	-	27260156	BXPC3	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.14416896006251956	[329]	[317,314,313,296]	-3	hSpCas9	negative selection	5599562
88140964	88140987	12	+	27260156	BXPC3	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.08602976306498855	[347]	[320,350,288,417]	-2	hSpCas9	negative selection	5599563
88139515	88139538	12	-	27260156	BXPC3	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.3085515678099071	[173]	[169,242,220,276]	6	hSpCas9	negative selection	5599564
88141235	88141258	12	-	27260156	A673	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.3459457619696456	[587]	[820,845,971,942]	7	hSpCas9	negative selection	5656539
88141287	88141310	12	-	27260156	A673	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.40581328584437415	[194]	[205,176,123,204]	-7	hSpCas9	negative selection	5656540
88139546	88139569	12	-	27260156	A673	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.07507045858815597	[275]	[434,267,290,276]	-2	hSpCas9	negative selection	5656541
88140955	88140978	12	-	27260156	A673	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.2474230241159363	[329]	[383,258,247,458]	-6	hSpCas9	negative selection	5720813
88140964	88140987	12	+	27260156	A673	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.22601246261844987	[347]	[415,223,306,499]	-5	hSpCas9	negative selection	5720814
88139515	88139538	12	-	27260156	A673	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.36304504123939396	[173]	[292,300,224,256]	8	hSpCas9	negative selection	5720815
88141235	88141258	12	-	27260156	A375	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.20984389837123169	[587]	[784,929,896,603]	3	hSpCas9	negative selection	5777790
88141287	88141310	12	-	27260156	A375	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.25081221554774213	[194]	[165,267,201,144]	-4	hSpCas9	negative selection	5777791
88139546	88139569	12	-	27260156	A375	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.01936272430558872	[275]	[295,330,333,342]	0	hSpCas9	negative selection	5777792
88140955	88140978	12	-	27260156	A375	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.06844704118309808	[329]	[302,315,337,618]	1	hSpCas9	negative selection	5842064
88140964	88140987	12	+	27260156	A375	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.029123922294523708	[347]	[348,523,319,413]	0	hSpCas9	negative selection	5842065
88139515	88139538	12	-	27260156	A375	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.5793684263916389	[173]	[341,333,293,253]	8	hSpCas9	negative selection	5842066
88141235	88141258	12	-	27260156	COLO741	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.2870889748357606	[587]	[1153,770,847]	6	hSpCas9	negative selection	5899041
88141287	88141310	12	-	27260156	COLO741	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.22856738742881944	[194]	[226,175,233]	-5	hSpCas9	negative selection	5899042
88139546	88139569	12	-	27260156	COLO741	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.02966227660973786	[275]	[477,381,197]	0	hSpCas9	negative selection	5899043
88140955	88140978	12	-	27260156	COLO741	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.09628193936795693	[329]	[310,532,335]	-2	hSpCas9	negative selection	5963315
88140964	88140987	12	+	27260156	COLO741	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.1349297748239261	[347]	[452,458,312]	-3	hSpCas9	negative selection	5963316
88139515	88139538	12	-	27260156	COLO741	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.035545510500213595	[173]	[377,207,117]	0	hSpCas9	negative selection	5963317
88141235	88141258	12	-	27260156	CAL120	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.19743465461476012	[587]	[837,865,812]	3	hSpCas9	negative selection	6020292
88141287	88141310	12	-	27260156	CAL120	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.009529585377060501	[194]	[248,330,145]	0	hSpCas9	negative selection	6020293
88139546	88139569	12	-	27260156	CAL120	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.10131423443588372	[275]	[458,188,332]	-1	hSpCas9	negative selection	6020294
88140955	88140978	12	-	27260156	CAL120	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.49234222743471656	[329]	[276,226,367]	-6	hSpCas9	negative selection	6084566
88140964	88140987	12	+	27260156	CAL120	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	0.31334474893264425	[347]	[541,441,628]	5	hSpCas9	negative selection	6084567
88139515	88139538	12	-	27260156	CAL120	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	-0.5384022814803564	[173]	[124,81,234]	-6	hSpCas9	negative selection	6084568
88141235	88141258	12	-	27260156	CADOES1	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.26173897989267597	[587]	[601,712,725,578]	4	hSpCas9	negative selection	6141543
88141287	88141310	12	-	27260156	CADOES1	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.7323001015310606	[194]	[126,80,82,146]	-8	hSpCas9	negative selection	6141544
88139546	88139569	12	-	27260156	CADOES1	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.3191296305299082	[275]	[285,347,202,448]	5	hSpCas9	negative selection	6141545
88140955	88140978	12	-	27260156	CADOES1	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.04036509858217491	[329]	[508,258,252,237]	0	hSpCas9	negative selection	6205817
88140964	88140987	12	+	27260156	CADOES1	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.08513030934613419	[347]	[271,410,226,310]	-1	hSpCas9	negative selection	6205818
88139515	88139538	12	-	27260156	CADOES1	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.7086183468318167	[173]	[274,137,266,381]	9	hSpCas9	negative selection	6205819
88141235	88141258	12	-	27260156	EWS502	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.32106948667829066	[587]	[673,659,1047,745]	5	hSpCas9	negative selection	6262794
88141287	88141310	12	-	27260156	EWS502	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.2902111011520332	[194]	[173,192,215,84]	-5	hSpCas9	negative selection	6262795
88139546	88139569	12	-	27260156	EWS502	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.1707341100894838	[275]	[252,289,431,353]	3	hSpCas9	negative selection	6262796
88140955	88140978	12	-	27260156	EWS502	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.08276046496337996	[329]	[440,173,355,341]	-1	hSpCas9	negative selection	6327068
88140964	88140987	12	+	27260156	EWS502	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.1271934133805417	[347]	[371,348,336,281]	-2	hSpCas9	negative selection	6327069
88139515	88139538	12	-	27260156	EWS502	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.18096431567502536	[173]	[236,185,140,271]	3	hSpCas9	negative selection	6327070
88141235	88141258	12	-	27260156	EW8	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.02520400554125074	[587]	[560,633,328,449]	0	hSpCas9	negative selection	6384045
88141287	88141310	12	-	27260156	EW8	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.395263005053232	[194]	[177,75,68,171]	-6	hSpCas9	negative selection	6384046
88139546	88139569	12	-	27260156	EW8	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.002941504874032108	[275]	[175,253,235,218]	0	hSpCas9	negative selection	6384047
88140955	88140978	12	-	27260156	EW8	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.13585250901806767	[329]	[227,256,238,247]	-3	hSpCas9	negative selection	6448319
88140964	88140987	12	+	27260156	EW8	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.548483487170704	[347]	[226,94,161,294]	-7	hSpCas9	negative selection	6448320
88139515	88139538	12	-	27260156	EW8	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	-0.3617592665945013	[173]	[188,61,92,105]	-6	hSpCas9	negative selection	6448321
88141235	88141258	12	-	27260156	CORL105	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.37350445574265195	[587]	[1087,742,862,877]	7	hSpCas9	negative selection	6505296
88141287	88141310	12	-	27260156	CORL105	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.41051663216815304	[194]	[108,127,257,203]	-6	hSpCas9	negative selection	6505297
88139546	88139569	12	-	27260156	CORL105	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.212010327021656	[275]	[396,371,362,363]	4	hSpCas9	negative selection	6505298
88140955	88140978	12	-	27260156	CORL105	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.3328023659049514	[329]	[322,326,286,286]	-6	hSpCas9	negative selection	6569570
88140964	88140987	12	+	27260156	CORL105	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.1835134767077119	[347]	[491,292,433,233]	-3	hSpCas9	negative selection	6569571
88139515	88139538	12	-	27260156	CORL105	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.717767051540156	[173]	[325,177,409,439]	9	hSpCas9	negative selection	6569572
88141235	88141258	12	-	27260156	HS294T	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.4150156455274055	[587]	[305,361,223,319]	5	hSpCas9	negative selection	6626547
88141287	88141310	12	-	27260156	HS294T	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.007693824268589111	[194]	[105,22,41,137]	0	hSpCas9	negative selection	6626548
88139546	88139569	12	-	27260156	HS294T	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.16558856129602817	[275]	[66,53,58,342]	2	hSpCas9	negative selection	6626549
88140955	88140978	12	-	27260156	HS294T	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.3165665358313815	[329]	[120,51,155,75]	-4	hSpCas9	negative selection	6690821
88140964	88140987	12	+	27260156	HS294T	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-1.0205314396949339	[347]	[45,56,99,63]	-9	hSpCas9	negative selection	6690822
88139515	88139538	12	-	27260156	HS294T	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.06182922153222292	[173]	[74,64,46,97]	0	hSpCas9	negative selection	6690823
88141235	88141258	12	-	27260156	HCC44	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.39577466642976195	[587]	[1049,730,1074,712]	6	hSpCas9	negative selection	6747798
88141287	88141310	12	-	27260156	HCC44	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.3625776855833154	[194]	[165,193,182,140]	-5	hSpCas9	negative selection	6747799
88139546	88139569	12	-	27260156	HCC44	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.5067985399470251	[275]	[299,283,159,123]	-6	hSpCas9	negative selection	6747800
88140955	88140978	12	-	27260156	HCC44	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.5678289587151496	[329]	[319,225,185,270]	-7	hSpCas9	negative selection	6812072
88140964	88140987	12	+	27260156	HCC44	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	0.33883709942580104	[347]	[716,402,333,536]	5	hSpCas9	negative selection	6812073
88139515	88139538	12	-	27260156	HCC44	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.4632705339351628	[173]	[226,238,380,255]	7	hSpCas9	negative selection	6812074
88141235	88141258	12	-	27260156	G402	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.5231444346042586	[587]	[1565,1204,751,700]	6	hSpCas9	negative selection	6869049
88141287	88141310	12	-	27260156	G402	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-1.1407952821740015	[194]	[117,112,115,86]	-8	hSpCas9	negative selection	6869050
88139546	88139569	12	-	27260156	G402	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.2929180917237525	[275]	[203,242,376,262]	-4	hSpCas9	negative selection	6869051
88140955	88140978	12	-	27260156	G402	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.07080067520764322	[329]	[376,277,401,463]	-1	hSpCas9	negative selection	6933323
88140964	88140987	12	+	27260156	G402	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.49822883058553513	[347]	[443,324,249,208]	-6	hSpCas9	negative selection	6933324
88139515	88139538	12	-	27260156	G402	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.8019950421281251	[173]	[110,339,468,512]	8	hSpCas9	negative selection	6933325
88141235	88141258	12	-	27260156	L33	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.4412161136569697	[587]	[766,340,526,756]	8	hSpCas9	negative selection	6990300
88141287	88141310	12	-	27260156	L33	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.6041498927766475	[194]	[124,42,82,150]	-8	hSpCas9	negative selection	6990301
88139546	88139569	12	-	27260156	L33	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.05844515479286638	[275]	[349,92,226,210]	1	hSpCas9	negative selection	6990302
88140955	88140978	12	-	27260156	L33	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.22968060368191645	[329]	[262,119,163,308]	-5	hSpCas9	negative selection	7054574
88140964	88140987	12	+	27260156	L33	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.30731826206281376	[347]	[237,102,173,358]	-6	hSpCas9	negative selection	7054575
88139515	88139538	12	-	27260156	L33	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.25980769363217915	[173]	[167,95,122,235]	5	hSpCas9	negative selection	7054576
88141235	88141258	12	-	27260156	K562	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.5845726432360558	[587]	[695,910,780,742]	7	hSpCas9	negative selection	7111551
88141287	88141310	12	-	27260156	K562	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-1.1674159713338519	[194]	[97,93,55,63]	-8	hSpCas9	negative selection	7111552
88139546	88139569	12	-	27260156	K562	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.31574930823239794	[275]	[435,139,412,238]	4	hSpCas9	negative selection	7111553
88140955	88140978	12	-	27260156	K562	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.35464898763997965	[329]	[489,226,670,137]	4	hSpCas9	negative selection	7175825
88140964	88140987	12	+	27260156	K562	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	0.4468622189992894	[347]	[460,424,222,559]	5	hSpCas9	negative selection	7175826
88139515	88139538	12	-	27260156	K562	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.3387237329332369	[173]	[132,272,52,306]	4	hSpCas9	negative selection	7175827
88141235	88141258	12	-	27260156	HT29	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.4114927313679902	[587]	[1081,843,921,948]	7	hSpCas9	negative selection	7232802
88141287	88141310	12	-	27260156	HT29	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.5706640125551081	[194]	[143,202,197,101]	-7	hSpCas9	negative selection	7232803
88139546	88139569	12	-	27260156	HT29	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.29198902305104824	[275]	[461,519,292,381]	6	hSpCas9	negative selection	7232804
88140955	88140978	12	-	27260156	HT29	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.17311959268501065	[329]	[401,403,335,293]	-4	hSpCas9	negative selection	7297076
88140964	88140987	12	+	27260156	HT29	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.04807037416778753	[347]	[316,516,384,415]	-1	hSpCas9	negative selection	7297077
88139515	88139538	12	-	27260156	HT29	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.20812382664328588	[173]	[161,326,221,262]	4	hSpCas9	negative selection	7297078
88141235	88141258	12	-	27260156	MHHES1	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.4983373791841899	[587]	[895,1024,1034,800]	8	hSpCas9	negative selection	7354053
88141287	88141310	12	-	27260156	MHHES1	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.6718167271978535	[194]	[135,26,188,175]	-8	hSpCas9	negative selection	7354054
88139546	88139569	12	-	27260156	MHHES1	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.5265569499391997	[275]	[377,652,327,435]	8	hSpCas9	negative selection	7354055
88140955	88140978	12	-	27260156	MHHES1	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.3477648344488933	[329]	[305,226,332,290]	-6	hSpCas9	negative selection	7418327
88140964	88140987	12	+	27260156	MHHES1	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.23929714558205284	[347]	[341,411,277,303]	-4	hSpCas9	negative selection	7418328
88139515	88139538	12	-	27260156	MHHES1	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.4422512117378361	[173]	[475,140,288,184]	7	hSpCas9	negative selection	7418329
88141235	88141258	12	-	27260156	MEWO	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.44192111024311725	[587]	[916,653,703]	8	hSpCas9	negative selection	7475304
88141287	88141310	12	-	27260156	MEWO	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.06009853340133531	[194]	[198,89,240]	-1	hSpCas9	negative selection	7475305
88139546	88139569	12	-	27260156	MEWO	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.23050873596163268	[275]	[234,239,187]	-5	hSpCas9	negative selection	7475306
88140955	88140978	12	-	27260156	MEWO	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.1879746334964113	[329]	[376,335,346]	4	hSpCas9	negative selection	7539578
88140964	88140987	12	+	27260156	MEWO	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.49845417796110725	[347]	[305,224,174]	-8	hSpCas9	negative selection	7539579
88139515	88139538	12	-	27260156	MEWO	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.28357878706329354	[173]	[298,184,129]	6	hSpCas9	negative selection	7539580
88141235	88141258	12	-	27260156	LNCAPCLONEFGC	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.48580690825720435	[587]	[709,800,926,568]	7	hSpCas9	negative selection	7596555
88141287	88141310	12	-	27260156	LNCAPCLONEFGC	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.938321039977762	[194]	[89,57,78,141]	-8	hSpCas9	negative selection	7596556
88139546	88139569	12	-	27260156	LNCAPCLONEFGC	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.27023158213680276	[275]	[146,179,226,280]	-4	hSpCas9	negative selection	7596557
88140955	88140978	12	-	27260156	LNCAPCLONEFGC	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.021276244002477962	[329]	[341,239,309,290]	0	hSpCas9	negative selection	7660829
88140964	88140987	12	+	27260156	LNCAPCLONEFGC	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	0.08160472962929427	[347]	[375,255,377,334]	1	hSpCas9	negative selection	7660830
88139515	88139538	12	-	27260156	LNCAPCLONEFGC	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.6263875138105509	[173]	[141,286,322,231]	8	hSpCas9	negative selection	7660831
88141235	88141258	12	-	27260156	PANC0327	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	-0.0017601556708873867	[587]	[704,510,474,411]	0	hSpCas9	negative selection	7717806
88141287	88141310	12	-	27260156	PANC0327	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.19460043342016942	[194]	[240,71,153,155]	-3	hSpCas9	negative selection	7717807
88139546	88139569	12	-	27260156	PANC0327	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.2728718276225929	[275]	[215,239,223,127]	-4	hSpCas9	negative selection	7717808
88140955	88140978	12	-	27260156	PANC0327	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.4524528510694096	[329]	[117,246,344,134]	-6	hSpCas9	negative selection	7782080
88140964	88140987	12	+	27260156	PANC0327	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.4159972163290888	[347]	[329,189,155,263]	-6	hSpCas9	negative selection	7782081
88139515	88139538	12	-	27260156	PANC0327	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	-0.10786169910018417	[173]	[213,76,127,168]	-2	hSpCas9	negative selection	7782082
88141235	88141258	12	-	27260156	NCIH2009	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.6324704791469611	[587]	[1308,1079,1439]	8	hSpCas9	negative selection	7839057
88141287	88141310	12	-	27260156	NCIH2009	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.838640865432849	[194]	[152,201,100]	-7	hSpCas9	negative selection	7839058
88139546	88139569	12	-	27260156	NCIH2009	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.08144190985470423	[275]	[399,295,404]	-1	hSpCas9	negative selection	7839059
88140955	88140978	12	-	27260156	NCIH2009	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.4142327632028823	[329]	[874,596,421]	6	hSpCas9	negative selection	7903331
88140964	88140987	12	+	27260156	NCIH2009	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.2415925886891035	[347]	[419,397,416]	-3	hSpCas9	negative selection	7903332
88139515	88139538	12	-	27260156	NCIH2009	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	-0.13908464054834346	[173]	[116,242,280]	-2	hSpCas9	negative selection	7903333
88141235	88141258	12	-	27260156	NCIH1373	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.49954696084801736	[587]	[1506,673,821,218]	5	hSpCas9	negative selection	7960308
88141287	88141310	12	-	27260156	NCIH1373	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-1.3103140737676184	[194]	[89,27,109,34]	-8	hSpCas9	negative selection	7960309
88139546	88139569	12	-	27260156	NCIH1373	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.5993139431231028	[275]	[152,150,210,79]	-5	hSpCas9	negative selection	7960310
88140955	88140978	12	-	27260156	NCIH1373	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.10400778761093254	[329]	[609,330,232,62]	-1	hSpCas9	negative selection	8024582
88140964	88140987	12	+	27260156	NCIH1373	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.4044634400377016	[347]	[380,219,258,89]	-4	hSpCas9	negative selection	8024583
88139515	88139538	12	-	27260156	NCIH1373	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	-0.22202331635560912	[173]	[257,106,89,62]	-2	hSpCas9	negative selection	8024584
88141235	88141258	12	-	27260156	PATU8902	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.1372983391594308	[587]	[977,1116,784,723]	1	hSpCas9	negative selection	8081559
88141287	88141310	12	-	27260156	PATU8902	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-1.1173541936616787	[194]	[141,161,106,88]	-7	hSpCas9	negative selection	8081560
88139546	88139569	12	-	27260156	PATU8902	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.08274142782458915	[275]	[742,323,146,482]	0	hSpCas9	negative selection	8081561
88140955	88140978	12	-	27260156	PATU8902	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.26234225137601375	[329]	[553,230,293,482]	-3	hSpCas9	negative selection	8145833
88140964	88140987	12	+	27260156	PATU8902	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.377797033645876	[347]	[362,593,258,293]	-4	hSpCas9	negative selection	8145834
88139515	88139538	12	-	27260156	PATU8902	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.27921397587615093	[173]	[147,427,388,171]	3	hSpCas9	negative selection	8145835
88141235	88141258	12	-	27260156	PANC1	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.09230225970287809	[587]	[441,603,658,467]	1	hSpCas9	negative selection	8202810
88141287	88141310	12	-	27260156	PANC1	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	0.4057134398497777	[194]	[154,261,163,298]	6	hSpCas9	negative selection	8202811
88139546	88139569	12	-	27260156	PANC1	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.5856156229687759	[275]	[360,564,193,340]	8	hSpCas9	negative selection	8202812
88140955	88140978	12	-	27260156	PANC1	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.40886717396007916	[329]	[275,598,306,365]	6	hSpCas9	negative selection	8267084
88140964	88140987	12	+	27260156	PANC1	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.19364755246908327	[347]	[268,256,259,254]	-3	hSpCas9	negative selection	8267085
88139515	88139538	12	-	27260156	PANC1	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.2933596281639672	[173]	[163,128,260,167]	5	hSpCas9	negative selection	8267086
88141235	88141258	12	-	27260156	PANC0813	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.5928994121958784	[587]	[1060,948,1227,935]	8	hSpCas9	negative selection	8324061
88141287	88141310	12	-	27260156	PANC0813	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.7158677963371451	[194]	[151,136,117,150]	-7	hSpCas9	negative selection	8324062
88139546	88139569	12	-	27260156	PANC0813	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.3730086315815292	[275]	[138,324,263,261]	-5	hSpCas9	negative selection	8324063
88140955	88140978	12	-	27260156	PANC0813	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.240192097304048	[329]	[286,258,332,423]	-4	hSpCas9	negative selection	8388335
88140964	88140987	12	+	27260156	PANC0813	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.5092346565765754	[347]	[460,245,274,187]	-6	hSpCas9	negative selection	8388336
88139515	88139538	12	-	27260156	PANC0813	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.1910545827069403	[173]	[282,236,264,156]	3	hSpCas9	negative selection	8388337
88141235	88141258	12	-	27260156	RDES	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.25413354257509996	[587]	[719,689,841,1010]	4	hSpCas9	negative selection	8445312
88141287	88141310	12	-	27260156	RDES	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	0.027638645297221487	[194]	[190,235,250,238]	0	hSpCas9	negative selection	8445313
88139546	88139569	12	-	27260156	RDES	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.07583462038259958	[275]	[181,297,273,497]	-1	hSpCas9	negative selection	8445314
88140955	88140978	12	-	27260156	RDES	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.14105977156215666	[329]	[275,388,309,409]	-2	hSpCas9	negative selection	8509586
88140964	88140987	12	+	27260156	RDES	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.01252211803397163	[347]	[310,416,426,444]	0	hSpCas9	negative selection	8509587
88139515	88139538	12	-	27260156	RDES	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.32126196679136165	[173]	[198,224,307,280]	5	hSpCas9	negative selection	8509588
88141235	88141258	12	-	27260156	PC3	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.47680056414465827	[587]	[518,859,1168,901]	8	hSpCas9	negative selection	8566563
88141287	88141310	12	-	27260156	PC3	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.08047271544717716	[194]	[148,179,358,104]	-2	hSpCas9	negative selection	8566564
88139546	88139569	12	-	27260156	PC3	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.021824654171005764	[275]	[160,275,555,257]	0	hSpCas9	negative selection	8566565
88140955	88140978	12	-	27260156	PC3	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.32547996876758245	[329]	[126,276,476,291]	-6	hSpCas9	negative selection	8630837
88140964	88140987	12	+	27260156	PC3	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.23005212490020976	[347]	[205,319,551,206]	-5	hSpCas9	negative selection	8630838
88139515	88139538	12	-	27260156	PC3	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	-0.2091410718883262	[173]	[111,135,147,205]	-5	hSpCas9	negative selection	8630839
88141235	88141258	12	-	27260156	PATU8988T	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.3391675319850988	[587]	[729,754,527,880]	6	hSpCas9	negative selection	8687814
88141287	88141310	12	-	27260156	PATU8988T	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.1869368729545975	[194]	[88,214,218,140]	-3	hSpCas9	negative selection	8687815
88139546	88139569	12	-	27260156	PATU8988T	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.4060002442303733	[275]	[309,345,461,287]	7	hSpCas9	negative selection	8687816
88140955	88140978	12	-	27260156	PATU8988T	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.10132855113259265	[329]	[180,357,247,417]	-2	hSpCas9	negative selection	8752088
88140964	88140987	12	+	27260156	PATU8988T	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	0.008511946697756012	[347]	[423,325,233,371]	0	hSpCas9	negative selection	8752089
88139515	88139538	12	-	27260156	PATU8988T	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.3821111674746194	[173]	[215,308,150,208]	6	hSpCas9	negative selection	8752090
88141235	88141258	12	-	27260156	T47D	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.15572798288224876	[587]	[808,873,643,715]	3	hSpCas9	negative selection	8809065
88141287	88141310	12	-	27260156	T47D	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	0.0855984124446767	[194]	[254,271,178,256]	1	hSpCas9	negative selection	8809066
88139546	88139569	12	-	27260156	T47D	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.06056442362082526	[275]	[305,325,378,329]	1	hSpCas9	negative selection	8809067
88140955	88140978	12	-	27260156	T47D	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.06294596299017852	[329]	[386,395,347,337]	-1	hSpCas9	negative selection	8873339
88140964	88140987	12	+	27260156	T47D	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.15893201569272608	[347]	[437,329,348,337]	-4	hSpCas9	negative selection	8873340
88139515	88139538	12	-	27260156	T47D	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.3560732500103536	[173]	[304,205,238,293]	7	hSpCas9	negative selection	8873341
88141235	88141258	12	-	27260156	SU8686	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.47039205192020533	[587]	[705,729,933,893]	7	hSpCas9	negative selection	8930316
88141287	88141310	12	-	27260156	SU8686	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.8224592610631716	[194]	[110,66,87,187]	-8	hSpCas9	negative selection	8930317
88139546	88139569	12	-	27260156	SU8686	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.03912771773205859	[275]	[285,283,260,219]	0	hSpCas9	negative selection	8930318
88140955	88140978	12	-	27260156	SU8686	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	0.026171370560543528	[329]	[307,326,277,435]	0	hSpCas9	negative selection	8994590
88140964	88140987	12	+	27260156	SU8686	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.31240830579130463	[347]	[210,283,282,349]	-5	hSpCas9	negative selection	8994591
88139515	88139538	12	-	27260156	SU8686	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.3430059947666759	[173]	[183,232,254,201]	6	hSpCas9	negative selection	8994592
88141235	88141258	12	-	27260156	SKES1	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.3994961924324086	[587]	[755,1018,740,616]	7	hSpCas9	negative selection	9051567
88141287	88141310	12	-	27260156	SKES1	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.29531672298163714	[194]	[179,119,176,153]	-6	hSpCas9	negative selection	9051568
88139546	88139569	12	-	27260156	SKES1	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.007581629637865683	[275]	[184,325,247,331]	0	hSpCas9	negative selection	9051569
88140955	88140978	12	-	27260156	SKES1	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.05357100082553223	[329]	[351,363,203,352]	-1	hSpCas9	negative selection	9115841
88140964	88140987	12	+	27260156	SKES1	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.1056575350816863	[347]	[481,372,267,206]	-2	hSpCas9	negative selection	9115842
88139515	88139538	12	-	27260156	SKES1	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.06445091770489908	[173]	[224,162,187,154]	1	hSpCas9	negative selection	9115843
88141235	88141258	12	-	27260156	TOV112D	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.3222587695003462	[587]	[941,806,611,620]	6	hSpCas9	negative selection	9172818
88141287	88141310	12	-	27260156	TOV112D	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.02518966814469148	[194]	[208,245,130,195]	0	hSpCas9	negative selection	9172819
88139546	88139569	12	-	27260156	TOV112D	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.030423574680243926	[275]	[321,319,270,187]	0	hSpCas9	negative selection	9172820
88140955	88140978	12	-	27260156	TOV112D	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.495051387719568	[329]	[279,157,153,327]	-7	hSpCas9	negative selection	9237092
88140964	88140987	12	+	27260156	TOV112D	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.4379531570105335	[347]	[212,383,231,227]	-7	hSpCas9	negative selection	9237093
88139515	88139538	12	-	27260156	TOV112D	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.42256100314604605	[173]	[214,366,142,239]	7	hSpCas9	negative selection	9237094
88141235	88141258	12	-	27260156	TC71	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.33512527756476157	[587]	[820,650,859,848]	7	hSpCas9	negative selection	9294069
88141287	88141310	12	-	27260156	TC71	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.49343385322238786	[194]	[76,223,131,163]	-8	hSpCas9	negative selection	9294070
88139546	88139569	12	-	27260156	TC71	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	0.3325521899164334	[275]	[438,289,378,380]	7	hSpCas9	negative selection	9294071
88140955	88140978	12	-	27260156	TC71	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.06508279783964666	[329]	[334,326,402,281]	-2	hSpCas9	negative selection	9358343
88140964	88140987	12	+	27260156	TC71	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.5424204557049866	[347]	[179,277,244,327]	-9	hSpCas9	negative selection	9358344
88139515	88139538	12	-	27260156	TC71	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	-0.14394462167731703	[173]	[191,138,119,228]	-4	hSpCas9	negative selection	9358345
88141235	88141258	12	-	27260156	TC32	viability	CCTGCCCCGTCAAGAAGAACTGG	CEP290	ENSG00000198707	0.40195418426464985	[587]	[719,589,978,680]	7	hSpCas9	negative selection	9415320
88141287	88141310	12	-	27260156	TC32	viability	AGATGCCACCTAATATAAACTGG	CEP290	ENSG00000198707	-0.33337523560434223	[194]	[157,87,210,147]	-6	hSpCas9	negative selection	9415321
88139546	88139569	12	-	27260156	TC32	viability	TTAGATGAAAGCTCAAGAAGTGG	CEP290	ENSG00000198707	-0.05651401240430076	[275]	[192,171,269,396]	-1	hSpCas9	negative selection	9415322
88140955	88140978	12	-	27260156	TC32	viability	AATTACTCAGTCACTAATGAAGG	CEP290	ENSG00000198707	-0.10377923392180965	[329]	[308,173,380,332]	-2	hSpCas9	negative selection	9479594
88140964	88140987	12	+	27260156	TC32	viability	GTGACTGAGTAATTCTGAAAAGG	CEP290	ENSG00000198707	-0.04951824829580892	[347]	[298,282,362,321]	-1	hSpCas9	negative selection	9479595
88139515	88139538	12	-	27260156	TC32	viability	TTGGAAGAAGTAGAAAAAGCTGG	CEP290	ENSG00000198707	0.4269187117496338	[173]	[257,171,235,214]	7	hSpCas9	negative selection	9479596
88080310	88080333	12	-	27869803	HPAFII	viability after 27 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.7153168361131792	[399]	[353,337,NaN]	6	hSpCas9	negative selection	9548773
88086450	88086473	12	-	27869803	HPAFII	viability after 27 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-1.8184141055916285	[135]	[22,17,NaN]	-8	hSpCas9	negative selection	9548774
88089211	88089234	12	-	27869803	HPAFII	viability after 27 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.7919396746429582	[386]	[258,429,NaN]	6	hSpCas9	negative selection	9548775
88096900	88096923	12	-	27869803	HPAFII	viability after 27 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	0.019984556850967505	[278]	[199,105,NaN]	0	hSpCas9	negative selection	9548776
88111735	88111758	12	-	27869803	HPAFII	viability after 27 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.22366979347336424	[505]	[416,221,NaN]	1	hSpCas9	negative selection	9548777
88118503	88118526	12	-	27869803	HPAFII	viability after 27 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.904697038499177	[802]	[731,838,NaN]	7	hSpCas9	negative selection	9548778
88080310	88080333	12	-	27869803	HPAFII	viability after 15 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.5754630428088447	[399]	[877,492,NaN]	6	hSpCas9	negative selection	9631222
88086450	88086473	12	-	27869803	HPAFII	viability after 15 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-1.2053237297486286	[135]	[100,39,NaN]	-8	hSpCas9	negative selection	9631223
88089211	88089234	12	-	27869803	HPAFII	viability after 15 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.29945755350915293	[386]	[501,517,NaN]	3	hSpCas9	negative selection	9631224
88096900	88096923	12	-	27869803	HPAFII	viability after 15 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.0785369656959704	[278]	[418,199,NaN]	-1	hSpCas9	negative selection	9631225
88111735	88111758	12	-	27869803	HPAFII	viability after 15 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.27760766720712904	[505]	[1022,432,NaN]	3	hSpCas9	negative selection	9631226
88118503	88118526	12	-	27869803	HPAFII	viability after 15 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.39082645076098266	[802]	[1601,838,NaN]	4	hSpCas9	negative selection	9631227
88080310	88080333	12	-	27869803	ASPC1	viability after 36 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	-0.09935096979355174	[1030]	[347,447,234]	-1	hSpCas9	negative selection	9713671
88086450	88086473	12	-	27869803	ASPC1	viability after 36 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-0.31032883611669515	[242]	[110,13,80]	-3	hSpCas9	negative selection	9713672
88089211	88089234	12	-	27869803	ASPC1	viability after 36 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	1.3086995343638992	[1022]	[2212,418,312]	9	hSpCas9	negative selection	9713673
88096900	88096923	12	-	27869803	ASPC1	viability after 36 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	0.03203422764361627	[584]	[362,37,233]	0	hSpCas9	negative selection	9713674
88111735	88111758	12	-	27869803	ASPC1	viability after 36 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.40749045198662914	[1204]	[869,484,390]	4	hSpCas9	negative selection	9713675
88118503	88118526	12	-	27869803	ASPC1	viability after 36 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.17819949877462737	[1985]	[942,976,511]	1	hSpCas9	negative selection	9713676
88080310	88080333	12	-	27869803	PATU8988S	viability after 35 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.5990795989411795	[761]	[407,521,NaN]	6	hSpCas9	negative selection	9796120
88086450	88086473	12	-	27869803	PATU8988S	viability after 35 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	0.4913901861552621	[224]	[79,174,NaN]	5	hSpCas9	negative selection	9796121
88089211	88089234	12	-	27869803	PATU8988S	viability after 35 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.8691628402753364	[739]	[496,591,NaN]	8	hSpCas9	negative selection	9796122
88096900	88096923	12	-	27869803	PATU8988S	viability after 35 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.2526376403815813	[589]	[177,220,NaN]	-3	hSpCas9	negative selection	9796123
88111735	88111758	12	-	27869803	PATU8988S	viability after 35 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.598386119431024	[1090]	[560,769,NaN]	6	hSpCas9	negative selection	9796124
88118503	88118526	12	-	27869803	PATU8988S	viability after 35 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.44859976585072503	[1542]	[669,1026,NaN]	5	hSpCas9	negative selection	9796125
88080310	88080333	12	-	27869803	PATU8988S	viability after 31 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	0.3263040406787406	[761]	[365,399,NaN]	4	hSpCas9	negative selection	9878569
88086450	88086473	12	-	27869803	PATU8988S	viability after 31 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	0.2411310206874775	[224]	[98,114,NaN]	3	hSpCas9	negative selection	9878570
88089211	88089234	12	-	27869803	PATU8988S	viability after 31 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.6482432016241542	[739]	[322,639,NaN]	7	hSpCas9	negative selection	9878571
88096900	88096923	12	-	27869803	PATU8988S	viability after 31 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	-0.3306148123421829	[589]	[172,204,NaN]	-4	hSpCas9	negative selection	9878572
88111735	88111758	12	-	27869803	PATU8988S	viability after 31 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.27370199598381095	[1090]	[473,591,NaN]	3	hSpCas9	negative selection	9878573
88118503	88118526	12	-	27869803	PATU8988S	viability after 31 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.53319804510703	[1542]	[720,1105,NaN]	6	hSpCas9	negative selection	9878574
88080310	88080333	12	-	27869803	HPAFII	viability after 35 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	1.4557266106618347	[399]	[617,484,NaN]	8	hSpCas9	negative selection	9961018
88086450	88086473	12	-	27869803	HPAFII	viability after 35 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-2.8180725364759343	[135]	[5,13,NaN]	-8	hSpCas9	negative selection	9961019
88089211	88089234	12	-	27869803	HPAFII	viability after 35 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.687910009343912	[386]	[126,527,NaN]	4	hSpCas9	negative selection	9961020
88096900	88096923	12	-	27869803	HPAFII	viability after 35 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	0.44191959684047166	[278]	[276,95,NaN]	3	hSpCas9	negative selection	9961021
88111735	88111758	12	-	27869803	HPAFII	viability after 35 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.48447089071758076	[505]	[427,279,NaN]	3	hSpCas9	negative selection	9961022
88118503	88118526	12	-	27869803	HPAFII	viability after 35 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.8960173409394174	[802]	[684,836,NaN]	6	hSpCas9	negative selection	9961023
88080310	88080333	12	-	27869803	HPAFII	viability after 31 days	TCTTCTGGACCAGTCACAAAAGG	CEP290	ENSG00000198707	1.1818059803024985	[399]	[492,526,NaN]	8	hSpCas9	negative selection	10043467
88086450	88086473	12	-	27869803	HPAFII	viability after 31 days	GGATCAAAGAGAAGTTGACCTGG	CEP290	ENSG00000198707	-1.22476497030557	[135]	[24,40,NaN]	-6	hSpCas9	negative selection	10043468
88089211	88089234	12	-	27869803	HPAFII	viability after 31 days	AGCTTTACCCTTGGCACAACAGG	CEP290	ENSG00000198707	0.8537302873098368	[386]	[224,574,NaN]	6	hSpCas9	negative selection	10043469
88096900	88096923	12	-	27869803	HPAFII	viability after 31 days	TATTGAACAAGCCTGGGAACAGG	CEP290	ENSG00000198707	0.6716501784696381	[278]	[347,141,NaN]	5	hSpCas9	negative selection	10043470
88111735	88111758	12	-	27869803	HPAFII	viability after 31 days	GCTCAGGGAATCTCGGAAAGAGG	CEP290	ENSG00000198707	0.4202603513848635	[505]	[435,318,NaN]	3	hSpCas9	negative selection	10043471
88118503	88118526	12	-	27869803	HPAFII	viability after 31 days	CGTCAAATGGCTCAAGAAAGAGG	CEP290	ENSG00000198707	0.8875860682298906	[802]	[749,924,NaN]	6	hSpCas9	negative selection	10043472
88139144	88139167	12	-	28162770	P31FUJ	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.7763000026928739	[315]	[635]	8	hSpCas9	negative selection	10131837
88120113	88120136	12	-	28162770	P31FUJ	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	-0.3953552172003385	[121]	[108]	-4	hSpCas9	negative selection	10131838
88102837	88102860	12	-	28162770	P31FUJ	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.4909525160252848	[372]	[615]	5	hSpCas9	negative selection	10131839
88131197	88131220	12	-	28162770	P31FUJ	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.22440474910840486	[235]	[323]	2	hSpCas9	negative selection	10131840
88121062	88121085	12	-	28162770	P31FUJ	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	-0.5953722837990871	[17]	[13]	-5	hSpCas9	negative selection	10131841
88093805	88093828	12	-	28162770	P31FUJ	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.7886775229960729	[199]	[405]	8	hSpCas9	negative selection	10131842
88084708	88084731	12	-	28162770	P31FUJ	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	-0.4081692909249392	[165]	[146]	-4	hSpCas9	negative selection	10131843
88077254	88077277	12	-	28162770	P31FUJ	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-1.232802204414379	[59]	[29]	-7	hSpCas9	negative selection	10131844
88054367	88054390	12	-	28162770	P31FUJ	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	0.18871484817529138	[721]	[966]	2	hSpCas9	negative selection	10131845
88136669	88136692	12	-	28162770	P31FUJ	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-0.8692114705542109	[313]	[201]	-6	hSpCas9	negative selection	10131846
88139144	88139167	12	-	28162770	TF1	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	NaN	[NaN]	[489]	1	hSpCas9	negative selection	10301203
88120113	88120136	12	-	28162770	TF1	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10301204
88102837	88102860	12	-	28162770	TF1	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	NaN	[NaN]	[318]	1	hSpCas9	negative selection	10301205
88131197	88131220	12	-	28162770	TF1	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	NaN	[NaN]	[255]	1	hSpCas9	negative selection	10301206
88121062	88121085	12	-	28162770	TF1	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10301207
88093805	88093828	12	-	28162770	TF1	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	NaN	[NaN]	[250]	1	hSpCas9	negative selection	10301208
88084708	88084731	12	-	28162770	TF1	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10301209
88077254	88077277	12	-	28162770	TF1	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10301210
88054367	88054390	12	-	28162770	TF1	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	NaN	[NaN]	[622]	1	hSpCas9	negative selection	10301211
88136669	88136692	12	-	28162770	TF1	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	NaN	[NaN]	[121]	1	hSpCas9	negative selection	10301212
88139144	88139167	12	-	28162770	SKM1	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.5418817133067353	[121]	[313]	5	hSpCas9	negative selection	10470569
88120113	88120136	12	-	28162770	SKM1	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	-0.6226928897985988	[26]	[30]	-5	hSpCas9	negative selection	10470570
88102837	88102860	12	-	28162770	SKM1	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	1.0281028714949358	[113]	[410]	8	hSpCas9	negative selection	10470571
88131197	88131220	12	-	28162770	SKM1	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.07108309806148261	[97]	[181]	0	hSpCas9	negative selection	10470572
88121062	88121085	12	-	28162770	SKM1	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	-2.6293566200796095	[20]	[5]	-9	hSpCas9	negative selection	10470573
88093805	88093828	12	-	28162770	SKM1	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.7456828112673151	[55]	[165]	7	hSpCas9	negative selection	10470574
88084708	88084731	12	-	28162770	SKM1	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	-0.16148816429367252	[30]	[48]	-1	hSpCas9	negative selection	10470575
88077254	88077277	12	-	28162770	SKM1	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-1.8220016980220053	[7]	[3]	-8	hSpCas9	negative selection	10470576
88054367	88054390	12	-	28162770	SKM1	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	-0.1274147061263513	[151]	[245]	-1	hSpCas9	negative selection	10470577
88136669	88136692	12	-	28162770	SKM1	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-1.219965683941908	[111]	[84]	-7	hSpCas9	negative selection	10470578
88139144	88139167	12	-	28162770	SKM1	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.5418817133067353	[121]	[313]	5	hSpCas9	negative selection	10639935
88120113	88120136	12	-	28162770	SKM1	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	-0.6226928897985988	[26]	[30]	-5	hSpCas9	negative selection	10639936
88102837	88102860	12	-	28162770	SKM1	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	1.0281028714949358	[113]	[410]	8	hSpCas9	negative selection	10639937
88131197	88131220	12	-	28162770	SKM1	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.07108309806148261	[97]	[181]	0	hSpCas9	negative selection	10639938
88121062	88121085	12	-	28162770	SKM1	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	-2.6293566200796095	[20]	[5]	-9	hSpCas9	negative selection	10639939
88093805	88093828	12	-	28162770	SKM1	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.7456828112673151	[55]	[165]	7	hSpCas9	negative selection	10639940
88084708	88084731	12	-	28162770	SKM1	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	-0.16148816429367252	[30]	[48]	-1	hSpCas9	negative selection	10639941
88077254	88077277	12	-	28162770	SKM1	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-1.8220016980220053	[7]	[3]	-8	hSpCas9	negative selection	10639942
88054367	88054390	12	-	28162770	SKM1	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	-0.1274147061263513	[151]	[245]	-1	hSpCas9	negative selection	10639943
88136669	88136692	12	-	28162770	SKM1	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-1.219965683941908	[111]	[84]	-7	hSpCas9	negative selection	10639944
88139144	88139167	12	-	28162770	PL21	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.7218099622593906	[364]	[261]	6	hSpCas9	negative selection	10809301
88120113	88120136	12	-	28162770	PL21	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	-0.8993960590615944	[89]	[20]	-6	hSpCas9	negative selection	10809302
88102837	88102860	12	-	28162770	PL21	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.7053749227397419	[464]	[329]	6	hSpCas9	negative selection	10809303
88131197	88131220	12	-	28162770	PL21	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	-0.8349073326098806	[249]	[60]	-5	hSpCas9	negative selection	10809304
88121062	88121085	12	-	28162770	PL21	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	-0.18688350861992697	[33]	[12]	-1	hSpCas9	negative selection	10809305
88093805	88093828	12	-	28162770	PL21	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.43091982131848705	[195]	[114]	4	hSpCas9	negative selection	10809306
88084708	88084731	12	-	28162770	PL21	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	0.6670160452877818	[122]	[84]	6	hSpCas9	negative selection	10809307
88077254	88077277	12	-	28162770	PL21	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-1.2852872126809216	[27]	[4]	-7	hSpCas9	negative selection	10809308
88054367	88054390	12	-	28162770	PL21	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	-0.33964674767948244	[502]	[172]	-2	hSpCas9	negative selection	10809309
88136669	88136692	12	-	28162770	PL21	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-0.3246053633977294	[304]	[105]	-2	hSpCas9	negative selection	10809310
88139144	88139167	12	-	28162770	P31FUJ	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.7763000026928739	[315]	[635]	8	hSpCas9	negative selection	10978667
88120113	88120136	12	-	28162770	P31FUJ	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	-0.3953552172003385	[121]	[108]	-4	hSpCas9	negative selection	10978668
88102837	88102860	12	-	28162770	P31FUJ	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.4909525160252848	[372]	[615]	5	hSpCas9	negative selection	10978669
88131197	88131220	12	-	28162770	P31FUJ	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.22440474910840486	[235]	[323]	2	hSpCas9	negative selection	10978670
88121062	88121085	12	-	28162770	P31FUJ	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	-0.5953722837990871	[17]	[13]	-5	hSpCas9	negative selection	10978671
88093805	88093828	12	-	28162770	P31FUJ	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.7886775229960729	[199]	[405]	8	hSpCas9	negative selection	10978672
88084708	88084731	12	-	28162770	P31FUJ	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	-0.4081692909249392	[165]	[146]	-4	hSpCas9	negative selection	10978673
88077254	88077277	12	-	28162770	P31FUJ	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-1.232802204414379	[59]	[29]	-7	hSpCas9	negative selection	10978674
88054367	88054390	12	-	28162770	P31FUJ	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	0.18871484817529138	[721]	[966]	2	hSpCas9	negative selection	10978675
88136669	88136692	12	-	28162770	P31FUJ	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-0.8692114705542109	[313]	[201]	-6	hSpCas9	negative selection	10978676
88139144	88139167	12	-	28162770	OCIAML5	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.6174187124372231	[233]	[647]	5	hSpCas9	negative selection	11148033
88120113	88120136	12	-	28162770	OCIAML5	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	1.8050457156129944	[25]	[163]	9	hSpCas9	negative selection	11148034
88102837	88102860	12	-	28162770	OCIAML5	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.6665534350284632	[177]	[509]	6	hSpCas9	negative selection	11148035
88131197	88131220	12	-	28162770	OCIAML5	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.24498811318316238	[193]	[414]	2	hSpCas9	negative selection	11148036
88121062	88121085	12	-	28162770	OCIAML5	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	-1.1151009766977906	[17]	[14]	-6	hSpCas9	negative selection	11148037
88093805	88093828	12	-	28162770	OCIAML5	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.22193401057977996	[113]	[239]	1	hSpCas9	negative selection	11148038
88084708	88084731	12	-	28162770	OCIAML5	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	-0.11145319968264655	[78]	[131]	-1	hSpCas9	negative selection	11148039
88077254	88077277	12	-	28162770	OCIAML5	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-1.9224558987553948	[20]	[9]	-7	hSpCas9	negative selection	11148040
88054367	88054390	12	-	28162770	OCIAML5	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	0.3338838545043905	[377]	[859]	3	hSpCas9	negative selection	11148041
88136669	88136692	12	-	28162770	OCIAML5	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-0.4110698445224724	[178]	[242]	-3	hSpCas9	negative selection	11148042
88139144	88139167	12	-	28162770	EOL1	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.715432329031432	[666]	[576]	6	hSpCas9	negative selection	11317399
88120113	88120136	12	-	28162770	EOL1	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	-0.09651384395729501	[137]	[67]	0	hSpCas9	negative selection	11317400
88102837	88102860	12	-	28162770	EOL1	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.24348444611000608	[868]	[541]	2	hSpCas9	negative selection	11317401
88131197	88131220	12	-	28162770	EOL1	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.2610518683026889	[452]	[285]	2	hSpCas9	negative selection	11317402
88121062	88121085	12	-	28162770	EOL1	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	0.6444398523777992	[50]	[41]	6	hSpCas9	negative selection	11317403
88093805	88093828	12	-	28162770	EOL1	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	1.1162605748175556	[386]	[441]	8	hSpCas9	negative selection	11317404
88084708	88084731	12	-	28162770	EOL1	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	-0.12436182891041192	[179]	[86]	-1	hSpCas9	negative selection	11317405
88077254	88077277	12	-	28162770	EOL1	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-0.15074035573370237	[58]	[27]	-1	hSpCas9	negative selection	11317406
88054367	88054390	12	-	28162770	EOL1	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	0.8873947731530686	[589]	[574]	7	hSpCas9	negative selection	11317407
88136669	88136692	12	-	28162770	EOL1	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-0.05479275786337251	[415]	[210]	0	hSpCas9	negative selection	11317408
88139144	88139167	12	-	28162770	MOLM13	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.8960248696923374	[465]	[626]	6	hSpCas9	negative selection	11486765
88120113	88120136	12	-	28162770	MOLM13	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	0.1948708871381628	[144]	[119]	1	hSpCas9	negative selection	11486766
88102837	88102860	12	-	28162770	MOLM13	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.39412532687252444	[641]	[609]	3	hSpCas9	negative selection	11486767
88131197	88131220	12	-	28162770	MOLM13	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.033133647651229725	[441]	[326]	0	hSpCas9	negative selection	11486768
88121062	88121085	12	-	28162770	MOLM13	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	-1.3163819273999837	[30]	[8]	-6	hSpCas9	negative selection	11486769
88093805	88093828	12	-	28162770	MOLM13	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.3945527696028439	[342]	[325]	3	hSpCas9	negative selection	11486770
88084708	88084731	12	-	28162770	MOLM13	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	-0.00976009503394365	[258]	[185]	0	hSpCas9	negative selection	11486771
88077254	88077277	12	-	28162770	MOLM13	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-1.610113130456694	[37]	[8]	-7	hSpCas9	negative selection	11486772
88054367	88054390	12	-	28162770	MOLM13	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	0.3154269042265536	[697]	[627]	2	hSpCas9	negative selection	11486773
88136669	88136692	12	-	28162770	MOLM13	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-0.8391227213498174	[432]	[174]	-4	hSpCas9	negative selection	11486774
88139144	88139167	12	-	28162770	HEL	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.9994617664888001	[466]	[597]	8	hSpCas9	negative selection	11656131
88120113	88120136	12	-	28162770	HEL	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	1.6274720753470464	[94]	[187]	9	hSpCas9	negative selection	11656132
88102837	88102860	12	-	28162770	HEL	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.9839174057873163	[535]	[678]	8	hSpCas9	negative selection	11656133
88131197	88131220	12	-	28162770	HEL	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.34747868757507466	[334]	[272]	3	hSpCas9	negative selection	11656134
88121062	88121085	12	-	28162770	HEL	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	0.9364700350570669	[30]	[37]	7	hSpCas9	negative selection	11656135
88093805	88093828	12	-	28162770	HEL	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.07829865515254586	[348]	[235]	0	hSpCas9	negative selection	11656136
88084708	88084731	12	-	28162770	HEL	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	-0.17252128814259327	[182]	[103]	-1	hSpCas9	negative selection	11656137
88077254	88077277	12	-	28162770	HEL	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-1.1348687466631953	[47]	[13]	-6	hSpCas9	negative selection	11656138
88054367	88054390	12	-	28162770	HEL	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	0.3473913362163117	[604]	[492]	3	hSpCas9	negative selection	11656139
88136669	88136692	12	-	28162770	HEL	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-1.1868897190708996	[358]	[100]	-6	hSpCas9	negative selection	11656140
88139144	88139167	12	-	28162770	MV411	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.45935664088971484	[315]	[365]	4	hSpCas9	negative selection	11825497
88120113	88120136	12	-	28162770	MV411	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	-1.886418195952015	[78]	[17]	-8	hSpCas9	negative selection	11825498
88102837	88102860	12	-	28162770	MV411	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	1.008311636856957	[382]	[648]	8	hSpCas9	negative selection	11825499
88131197	88131220	12	-	28162770	MV411	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	-0.15159946980235317	[268]	[203]	-1	hSpCas9	negative selection	11825500
88121062	88121085	12	-	28162770	MV411	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	0.8797057662822882	[19]	[30]	7	hSpCas9	negative selection	11825501
88093805	88093828	12	-	28162770	MV411	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.15195724192854707	[202]	[189]	1	hSpCas9	negative selection	11825502
88084708	88084731	12	-	28162770	MV411	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	0.7415466210528179	[70]	[99]	6	hSpCas9	negative selection	11825503
88077254	88077277	12	-	28162770	MV411	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-1.9749548705536726	[41]	[8]	-8	hSpCas9	negative selection	11825504
88054367	88054390	12	-	28162770	MV411	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	-0.3682217471612972	[474]	[309]	-3	hSpCas9	negative selection	11825505
88136669	88136692	12	-	28162770	MV411	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-0.5511471616470968	[286]	[164]	-4	hSpCas9	negative selection	11825506
88139144	88139167	12	-	28162770	MONOMAC1	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.905168013267345	[251]	[540]	8	hSpCas9	negative selection	11994863
88120113	88120136	12	-	28162770	MONOMAC1	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	-0.35175944185819596	[58]	[52]	-3	hSpCas9	negative selection	11994864
88102837	88102860	12	-	28162770	MONOMAC1	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.4374138364807185	[276]	[429]	4	hSpCas9	negative selection	11994865
88131197	88131220	12	-	28162770	MONOMAC1	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	-0.4158089527173046	[198]	[170]	-4	hSpCas9	negative selection	11994866
88121062	88121085	12	-	28162770	MONOMAC1	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	1.6442654069213882	[11]	[42]	9	hSpCas9	negative selection	11994867
88093805	88093828	12	-	28162770	MONOMAC1	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	-0.4794365777602787	[134]	[110]	-4	hSpCas9	negative selection	11994868
88084708	88084731	12	-	28162770	MONOMAC1	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	1.5684978993034235	[74]	[254]	9	hSpCas9	negative selection	11994869
88077254	88077277	12	-	28162770	MONOMAC1	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-0.5755484703132834	[12]	[9]	-5	hSpCas9	negative selection	11994870
88054367	88054390	12	-	28162770	MONOMAC1	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	0.9256125424732495	[354]	[772]	8	hSpCas9	negative selection	11994871
88136669	88136692	12	-	28162770	MONOMAC1	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-1.4142675632802226	[185]	[79]	-8	hSpCas9	negative selection	11994872
88139144	88139167	12	-	28162770	OCIAML2	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	0.5509724292430496	[57]	[470]	5	hSpCas9	negative selection	12164229
88120113	88120136	12	-	28162770	OCIAML2	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	-0.5861070426620971	[12]	[47]	-4	hSpCas9	negative selection	12164230
88102837	88102860	12	-	28162770	OCIAML2	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.37736708131278895	[74]	[539]	3	hSpCas9	negative selection	12164231
88131197	88131220	12	-	28162770	OCIAML2	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.8926687040650614	[54]	[565]	8	hSpCas9	negative selection	12164232
88121062	88121085	12	-	28162770	OCIAML2	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	0.9444076740366825	[2]	[31]	8	hSpCas9	negative selection	12164233
88093805	88093828	12	-	28162770	OCIAML2	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	0.14336172409052705	[40]	[250]	1	hSpCas9	negative selection	12164234
88084708	88084731	12	-	28162770	OCIAML2	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	-0.7001116713649285	[16]	[57]	-5	hSpCas9	negative selection	12164235
88077254	88077277	12	-	28162770	OCIAML2	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-1.1487017303547988	[5]	[14]	-6	hSpCas9	negative selection	12164236
88054367	88054390	12	-	28162770	OCIAML2	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	0.14749953941419425	[85]	[527]	1	hSpCas9	negative selection	12164237
88136669	88136692	12	-	28162770	OCIAML2	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-2.705095078879184	[59]	[50]	-9	hSpCas9	negative selection	12164238
88139144	88139167	12	-	28162770	OCIAML3	viability	GAAACTGGAAAATGAACTGGAGG	CEP290	ENSG00000198707	-0.3519328531260154	[103]	[245]	-3	hSpCas9	negative selection	12333595
88120113	88120136	12	-	28162770	OCIAML3	viability	GAGGCACTTAGAGAGCGTGTGGG	CEP290	ENSG00000198707	-0.7866527182665589	[27]	[48]	-5	hSpCas9	negative selection	12333596
88102837	88102860	12	-	28162770	OCIAML3	viability	AAGTAACTTGGAACACCTGGAGG	CEP290	ENSG00000198707	0.6252586800255653	[98]	[460]	6	hSpCas9	negative selection	12333597
88131197	88131220	12	-	28162770	OCIAML3	viability	GTTGGCTCTTCGAAATGAGGAGG	CEP290	ENSG00000198707	0.8061151849433976	[78]	[416]	7	hSpCas9	negative selection	12333598
88121062	88121085	12	-	28162770	OCIAML3	viability	GAGAACAGCTGAACTGGCTGAGG	CEP290	ENSG00000198707	-0.009045139603006902	[7]	[23]	0	hSpCas9	negative selection	12333599
88093805	88093828	12	-	28162770	OCIAML3	viability	GACTTCGTTAAAGCAAATGGAGG	CEP290	ENSG00000198707	-0.02719248631326665	[79]	[236]	0	hSpCas9	negative selection	12333600
88084708	88084731	12	-	28162770	OCIAML3	viability	TGAGCTAGGCAGAAAAGAGATGG	CEP290	ENSG00000198707	-0.857042046157957	[35]	[59]	-6	hSpCas9	negative selection	12333601
88077254	88077277	12	-	28162770	OCIAML3	viability	GAACCAATTAGAGGGAAAGGTGG	CEP290	ENSG00000198707	-0.594007640324163	[11]	[23]	-4	hSpCas9	negative selection	12333602
88054367	88054390	12	-	28162770	OCIAML3	viability	GAAGGTGCTGAGACAGAGCAAGG	CEP290	ENSG00000198707	0.44781253537046406	[135]	[559]	4	hSpCas9	negative selection	12333603
88136669	88136692	12	-	28162770	OCIAML3	viability	GGAGGACATGGAAAAGGAGTTGG	CEP290	ENSG00000198707	-0.14654866335294203	[109]	[299]	-1	hSpCas9	negative selection	12333604