Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:23440
• Symbol:otp
• Description:orthopedia homeobox

DataSource: http://genomecrispr.dkfz.de/#!/results/otp

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
77637192	77637215	5	-	26472758	Jiyoye	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	-0.6632139463855244	[20]	[9]	-5	hSpCas9	negative selection	114536
77637027	77637050	5	-	26472758	Jiyoye	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	6.240065395670615	[0]	[56]	9	hSpCas9	negative selection	114537
77637180	77637203	5	+	26472758	Jiyoye	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	1.4637589098722408	[49]	[103]	8	hSpCas9	negative selection	114538
77637108	77637131	5	-	26472758	Jiyoye	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.49252093654365936	[360]	[382]	4	hSpCas9	negative selection	114539
77637069	77637092	5	-	26472758	Jiyoye	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	0.6175951611762454	[120]	[139]	4	hSpCas9	negative selection	114540
77637013	77637036	5	-	26472758	Jiyoye	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.25593180112963587	[210]	[189]	2	hSpCas9	negative selection	114541
77636973	77636996	5	+	26472758	Jiyoye	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	1.1441409756720795	[23]	[39]	7	hSpCas9	negative selection	114542
77637167	77637190	5	-	26472758	Jiyoye	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	0.4660690705594419	[71]	[74]	3	hSpCas9	negative selection	114543
77637084	77637107	5	-	26472758	Jiyoye	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	-0.0728175596137402	[105]	[75]	0	hSpCas9	negative selection	114544
77637055	77637078	5	+	26472758	Jiyoye	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-1.2016338611696504	[60]	[19]	-7	hSpCas9	negative selection	114545
77637192	77637215	5	-	26472758	KBM7	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	2.4878923525334002	[39,18]	[96,55]	9	hSpCas9	negative selection	305654
77637027	77637050	5	-	26472758	KBM7	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	0.39821925812846365	[329,408]	[249,216]	4	hSpCas9	negative selection	305655
77637180	77637203	5	+	26472758	KBM7	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	-0.004961311586584305	[432,220]	[150,146]	0	hSpCas9	negative selection	305656
77637108	77637131	5	-	26472758	KBM7	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	-0.2353909022452767	[1502,1098]	[647,393]	-2	hSpCas9	negative selection	305657
77637069	77637092	5	-	26472758	KBM7	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	0.8580593459389604	[514,356]	[507,239]	8	hSpCas9	negative selection	305658
77637013	77637036	5	-	26472758	KBM7	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.2267411656356894	[768,424]	[312,326]	2	hSpCas9	negative selection	305659
77636973	77636996	5	+	26472758	KBM7	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	1.145902760622904	[174,106]	[241,55]	9	hSpCas9	negative selection	305660
77637167	77637190	5	-	26472758	KBM7	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	0.15180088940924905	[427,521]	[320,189]	1	hSpCas9	negative selection	305661
77637084	77637107	5	-	26472758	KBM7	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	1.0191759465785588	[375,267]	[310,295]	9	hSpCas9	negative selection	305662
77637055	77637078	5	+	26472758	KBM7	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-1.3052816410993313	[285,245]	[69,32]	-7	hSpCas9	negative selection	305663
77637192	77637215	5	-	26472758	Raji	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	-1.8468127750132761	[30]	[1]	-8	hSpCas9	negative selection	496772
77637027	77637050	5	-	26472758	Raji	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	0.1639670637399669	[199]	[51]	1	hSpCas9	negative selection	496773
77637180	77637203	5	+	26472758	Raji	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	-0.708191893488973	[175]	[24]	-5	hSpCas9	negative selection	496774
77637108	77637131	5	-	26472758	Raji	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.09516758566396044	[592]	[146]	0	hSpCas9	negative selection	496775
77637069	77637092	5	-	26472758	Raji	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	-0.06754214712707934	[288]	[63]	0	hSpCas9	negative selection	496776
77637013	77637036	5	-	26472758	Raji	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.4351881965976311	[391]	[122]	4	hSpCas9	negative selection	496777
77636973	77636996	5	+	26472758	Raji	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	2.3418487890106223	[16]	[19]	9	hSpCas9	negative selection	496778
77637167	77637190	5	-	26472758	Raji	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	-0.8584007492884876	[249]	[31]	-6	hSpCas9	negative selection	496779
77637084	77637107	5	-	26472758	Raji	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	0.02585364987700134	[181]	[42]	0	hSpCas9	negative selection	496780
77637055	77637078	5	+	26472758	Raji	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-0.7486061619348812	[180]	[24]	-5	hSpCas9	negative selection	496781
77637192	77637215	5	-	26472758	K562	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	-2.418546285055983	[56]	[8]	-8	hSpCas9	negative selection	687890
77637027	77637050	5	-	26472758	K562	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	0.3115329235249838	[293]	[307]	2	hSpCas9	negative selection	687891
77637180	77637203	5	+	26472758	K562	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	-0.12594972227866863	[211]	[163]	-1	hSpCas9	negative selection	687892
77637108	77637131	5	-	26472758	K562	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.39021545821586723	[1024]	[1133]	3	hSpCas9	negative selection	687893
77637069	77637092	5	-	26472758	K562	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	-1.186472722813234	[487]	[180]	-6	hSpCas9	negative selection	687894
77637013	77637036	5	-	26472758	K562	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.6568591154592515	[416]	[554]	5	hSpCas9	negative selection	687895
77636973	77636996	5	+	26472758	K562	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	0.9322296359793534	[202]	[326]	7	hSpCas9	negative selection	687896
77637167	77637190	5	-	26472758	K562	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	-0.18874857571793585	[346]	[256]	-1	hSpCas9	negative selection	687897
77637084	77637107	5	-	26472758	K562	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	-0.3770696490798233	[259]	[168]	-2	hSpCas9	negative selection	687898
77637055	77637078	5	+	26472758	K562	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-5.188540679609659	[215]	[4]	-9	hSpCas9	negative selection	687899
77630460	77630483	5	-	26627737	DLD1	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.3634441705567747	[233]	[64,79,130]	4	hSpCas9	negative selection	829526
77630528	77630551	5	+	26627737	DLD1	viability	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.5310910026365646	[1002]	[240,99,292]	-5	hSpCas9	negative selection	829527
77636911	77636934	5	+	26627737	DLD1	viability	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-0.30552328818625485	[320]	[92,27,114]	-3	hSpCas9	negative selection	829528
77637034	77637057	5	+	26627737	DLD1	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.30800408228735865	[154]	[23,93,62]	3	hSpCas9	negative selection	829529
77638499	77638522	5	+	26627737	DLD1	viability	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.5585508684392813	[314]	[191,84,153]	5	hSpCas9	negative selection	829530
77638510	77638533	5	+	26627737	DLD1	viability	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	0.3061920219406793	[183]	[24,162,34]	3	hSpCas9	negative selection	829531
77630460	77630483	5	-	26627737	GBM cells	viability after 5 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.9894407692854055	[86]	[25,20]	-9	hSpCas9	negative selection	911841
77630528	77630551	5	+	26627737	GBM cells	viability after 5 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.6506933493875083	[261]	[116,61]	-8	hSpCas9	negative selection	911842
77636911	77636934	5	+	26627737	GBM cells	viability after 5 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-0.521929246074364	[165]	[61,61]	-7	hSpCas9	negative selection	911843
77637034	77637057	5	+	26627737	GBM cells	viability after 5 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.2125743537894471	[69]	[51,34]	3	hSpCas9	negative selection	911844
77638499	77638522	5	+	26627737	GBM cells	viability after 5 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.20074076371653837	[158]	[83,111]	3	hSpCas9	negative selection	911845
77638510	77638533	5	+	26627737	GBM cells	viability after 5 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	-0.5124005383504406	[128]	[64,31]	-7	hSpCas9	negative selection	911846
77630460	77630483	5	-	26627737	GBM cells	viability after 13 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-1.065690762253601	[86]	[21,22]	-8	hSpCas9	negative selection	994156
77630528	77630551	5	+	26627737	GBM cells	viability after 13 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.43062294634096726	[261]	[153,65]	-5	hSpCas9	negative selection	994157
77636911	77636934	5	+	26627737	GBM cells	viability after 13 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-0.21708568464533917	[165]	[82,72]	-3	hSpCas9	negative selection	994158
77637034	77637057	5	+	26627737	GBM cells	viability after 13 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	-0.013560216606817166	[69]	[46,29]	0	hSpCas9	negative selection	994159
77638499	77638522	5	+	26627737	GBM cells	viability after 13 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.3955817174518154	[158]	[118,108]	5	hSpCas9	negative selection	994160
77638510	77638533	5	+	26627737	GBM cells	viability after 13 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	-0.9489224355940269	[128]	[70,7]	-8	hSpCas9	negative selection	994161
77630460	77630483	5	-	26627737	GBM cells	viability after 21 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.5241569554636769	[86]	[35,29]	-5	hSpCas9	negative selection	1076471
77630528	77630551	5	+	26627737	GBM cells	viability after 21 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.33471403963466856	[261]	[115,109]	-3	hSpCas9	negative selection	1076472
77636911	77636934	5	+	26627737	GBM cells	viability after 21 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-0.45796094448675284	[165]	[61,68]	-4	hSpCas9	negative selection	1076473
77637034	77637057	5	+	26627737	GBM cells	viability after 21 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.17011459413800245	[69]	[35,48]	1	hSpCas9	negative selection	1076474
77638499	77638522	5	+	26627737	GBM cells	viability after 21 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.7362731261842387	[158]	[157,130]	7	hSpCas9	negative selection	1076475
77638510	77638533	5	+	26627737	GBM cells	viability after 21 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	-1.401864201055494	[128]	[25,26]	-8	hSpCas9	negative selection	1076476
77630460	77630483	5	-	26627737	RPE1	viability after 9 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	2.3343605303683668	[68]	[111,104]	9	hSpCas9	negative selection	1158786
77630528	77630551	5	+	26627737	RPE1	viability after 9 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	0.15567932626732653	[747]	[159,390]	1	hSpCas9	negative selection	1158787
77636911	77636934	5	+	26627737	RPE1	viability after 9 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-2.922724256963253	[917]	[19,60]	-9	hSpCas9	negative selection	1158788
77637034	77637057	5	+	26627737	RPE1	viability after 9 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	3.312827249973814	[58]	[176,191]	9	hSpCas9	negative selection	1158789
77638499	77638522	5	+	26627737	RPE1	viability after 9 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.06445291812880932	[956]	[242,403]	0	hSpCas9	negative selection	1158790
77638510	77638533	5	+	26627737	RPE1	viability after 9 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	1.684297727805156	[221]	[218,228]	8	hSpCas9	negative selection	1158791
77630460	77630483	5	-	26627737	RPE1	viability after 12 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	3.098394462900491	[68]	[167,148]	9	hSpCas9	negative selection	1241101
77630528	77630551	5	+	26627737	RPE1	viability after 12 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.01581645979230551	[747]	[190,206]	0	hSpCas9	negative selection	1241102
77636911	77636934	5	+	26627737	RPE1	viability after 12 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-2.026354076313467	[917]	[27,94]	-8	hSpCas9	negative selection	1241103
77637034	77637057	5	+	26627737	RPE1	viability after 12 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	2.9719796501542306	[58]	[119,128]	9	hSpCas9	negative selection	1241104
77638499	77638522	5	+	26627737	RPE1	viability after 12 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	-0.5484724425568461	[956]	[219,128]	-4	hSpCas9	negative selection	1241105
77638510	77638533	5	+	26627737	RPE1	viability after 12 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	1.0858291398640108	[221]	[197,50]	6	hSpCas9	negative selection	1241106
77630460	77630483	5	-	26627737	RPE1	viability after 15 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	3.314953196962815	[68]	[292,98]	9	hSpCas9	negative selection	1323416
77630528	77630551	5	+	26627737	RPE1	viability after 15 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.275296678013395	[747]	[155,192]	-2	hSpCas9	negative selection	1323417
77636911	77636934	5	+	26627737	RPE1	viability after 15 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-2.8914117132092096	[917]	[6,61]	-9	hSpCas9	negative selection	1323418
77637034	77637057	5	+	26627737	RPE1	viability after 15 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	3.672312908769954	[58]	[168,254]	9	hSpCas9	negative selection	1323419
77638499	77638522	5	+	26627737	RPE1	viability after 15 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	-0.4418873005091799	[956]	[210,187]	-3	hSpCas9	negative selection	1323420
77638510	77638533	5	+	26627737	RPE1	viability after 15 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	1.1746415482963517	[221]	[98,182]	6	hSpCas9	negative selection	1323421
77630460	77630483	5	-	26627737	RPE1	viability after 18 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	2.9790009980979044	[68]	[155,136]	9	hSpCas9	negative selection	1405731
77630528	77630551	5	+	26627737	RPE1	viability after 18 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	0.4635091935554233	[747]	[302,251]	3	hSpCas9	negative selection	1405732
77636911	77636934	5	+	26627737	RPE1	viability after 18 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-2.1057064024970233	[917]	[0,117]	-8	hSpCas9	negative selection	1405733
77637034	77637057	5	+	26627737	RPE1	viability after 18 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	3.4047454595377644	[58]	[186,148]	9	hSpCas9	negative selection	1405734
77638499	77638522	5	+	26627737	RPE1	viability after 18 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.5366535485135411	[956]	[538,198]	3	hSpCas9	negative selection	1405735
77638510	77638533	5	+	26627737	RPE1	viability after 18 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	1.0729663736783142	[221]	[199,46]	6	hSpCas9	negative selection	1405736
77630460	77630483	5	-	26627737	HeLa	viability after 8 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	1.798360475776069	[31]	[20,65,51]	9	hSpCas9	negative selection	1488046
77630528	77630551	5	+	26627737	HeLa	viability after 8 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	0.19005036467148856	[512]	[217,432,114]	1	hSpCas9	negative selection	1488047
77636911	77636934	5	+	26627737	HeLa	viability after 8 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	0.7115911529813664	[156]	[180,89,81]	6	hSpCas9	negative selection	1488048
77637034	77637057	5	+	26627737	HeLa	viability after 8 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	2.60659673370667	[25]	[43,69,85]	9	hSpCas9	negative selection	1488049
77638499	77638522	5	+	26627737	HeLa	viability after 8 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.36635126272372154	[206]	[187,116,62]	3	hSpCas9	negative selection	1488050
77638510	77638533	5	+	26627737	HeLa	viability after 8 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	7.105552509658508	[0]	[177,0,28]	9	hSpCas9	negative selection	1488051
77630460	77630483	5	-	26627737	HeLa	viability after 12 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	1.8802960455474524	[31]	[63,43,38]	9	hSpCas9	negative selection	1570361
77630528	77630551	5	+	26627737	HeLa	viability after 12 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	0.21316595957002876	[512]	[551,105,102]	2	hSpCas9	negative selection	1570362
77636911	77636934	5	+	26627737	HeLa	viability after 12 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	0.27942367523611766	[156]	[49,25,164]	2	hSpCas9	negative selection	1570363
77637034	77637057	5	+	26627737	HeLa	viability after 12 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	2.612691796212938	[25]	[44,70,79]	9	hSpCas9	negative selection	1570364
77638499	77638522	5	+	26627737	HeLa	viability after 12 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	1.535811834388436	[206]	[220,288,228]	8	hSpCas9	negative selection	1570365
77638510	77638533	5	+	26627737	HeLa	viability after 12 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	6.551059053232601	[0]	[0,77,31]	9	hSpCas9	negative selection	1570366
77630460	77630483	5	-	26627737	HeLa	viability after 15 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	1.8835277053248376	[31]	[51,57,32]	9	hSpCas9	negative selection	1652676
77630528	77630551	5	+	26627737	HeLa	viability after 15 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.014161577934724778	[512]	[336,119,157]	0	hSpCas9	negative selection	1652677
77636911	77636934	5	+	26627737	HeLa	viability after 15 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	0.4802140710811936	[156]	[63,75,130]	4	hSpCas9	negative selection	1652678
77637034	77637057	5	+	26627737	HeLa	viability after 15 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	1.8165033704033893	[25]	[35,48,25]	9	hSpCas9	negative selection	1652679
77638499	77638522	5	+	26627737	HeLa	viability after 15 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.6711091643891236	[206]	[43,209,150]	5	hSpCas9	negative selection	1652680
77638510	77638533	5	+	26627737	HeLa	viability after 15 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	5.633628550504244	[0]	[1,24,34]	9	hSpCas9	negative selection	1652681
77630460	77630483	5	-	26627737	HeLa	viability after 18 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	1.8787255263892217	[31]	[32,49,32]	9	hSpCas9	negative selection	1734991
77630528	77630551	5	+	26627737	HeLa	viability after 18 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.040241741326235425	[512]	[215,102,157]	0	hSpCas9	negative selection	1734992
77636911	77636934	5	+	26627737	HeLa	viability after 18 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	0.5205248809039081	[156]	[46,63,130]	4	hSpCas9	negative selection	1734993
77637034	77637057	5	+	26627737	HeLa	viability after 18 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	1.8202100691070706	[25]	[23,40,25]	9	hSpCas9	negative selection	1734994
77638499	77638522	5	+	26627737	HeLa	viability after 18 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.7144988076946556	[206]	[30,181,150]	5	hSpCas9	negative selection	1734995
77638510	77638533	5	+	26627737	HeLa	viability after 18 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	5.577412878131519	[0]	[1,17,34]	9	hSpCas9	negative selection	1734996
77630460	77630483	5	-	26627737	HCT116	viability after 6 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	2.5018391688732105	[117]	[77,119]	9	hSpCas9	negative selection	1817306
77630528	77630551	5	+	26627737	HCT116	viability after 6 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.29648565320407994	[1146]	[160,138]	-2	hSpCas9	negative selection	1817307
77636911	77636934	5	+	26627737	HCT116	viability after 6 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	4.655273649242047	[20]	[10,122]	9	hSpCas9	negative selection	1817308
77637034	77637057	5	+	26627737	HCT116	viability after 6 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	2.000241380983968	[77]	[108,15]	8	hSpCas9	negative selection	1817309
77638499	77638522	5	+	26627737	HCT116	viability after 6 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	1.5013934682247663	[282]	[114,131]	7	hSpCas9	negative selection	1817310
77638510	77638533	5	+	26627737	HCT116	viability after 6 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	-0.8478463485151495	[185]	[3,22]	-5	hSpCas9	negative selection	1817311
77630460	77630483	5	-	26627737	HCT116	viability after 8 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.5434941928250285	[133]	[53,43,53]	-6	hSpCas9	negative selection	1899621
77630528	77630551	5	+	26627737	HCT116	viability after 8 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.5375831674735572	[350]	[127,167,103]	-6	hSpCas9	negative selection	1899622
77636911	77636934	5	+	26627737	HCT116	viability after 8 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-0.07111988043633355	[106]	[26,96,43]	0	hSpCas9	negative selection	1899623
77637034	77637057	5	+	26627737	HCT116	viability after 8 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	-0.3561716396756276	[151]	[102,30,62]	-4	hSpCas9	negative selection	1899624
77638499	77638522	5	+	26627737	HCT116	viability after 8 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.5972911796504626	[223]	[153,167,236]	6	hSpCas9	negative selection	1899625
77638510	77638533	5	+	26627737	HCT116	viability after 8 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	0.831381256537434	[85]	[63,136,51]	7	hSpCas9	negative selection	1899626
77630460	77630483	5	-	26627737	HCT116	viability after 9 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.31007815377290715	[117]	[30,20]	-2	hSpCas9	negative selection	1981936
77630528	77630551	5	+	26627737	HCT116	viability after 9 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-1.5896790807320156	[1146]	[146,65]	-8	hSpCas9	negative selection	1981937
77636911	77636934	5	+	26627737	HCT116	viability after 9 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	2.7660620762321915	[20]	[31,42]	9	hSpCas9	negative selection	1981938
77637034	77637057	5	+	26627737	HCT116	viability after 9 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	2.3382824430313076	[77]	[230,5]	9	hSpCas9	negative selection	1981939
77638499	77638522	5	+	26627737	HCT116	viability after 9 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.9163804710857537	[282]	[88,184]	6	hSpCas9	negative selection	1981940
77638510	77638533	5	+	26627737	HCT116	viability after 9 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	1.5686828395717594	[185]	[272,47]	8	hSpCas9	negative selection	1981941
77630460	77630483	5	-	26627737	HCT116	viability after 12 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-1.4487216567870105	[133]	[21,36,18]	-9	hSpCas9	negative selection	2064251
77630528	77630551	5	+	26627737	HCT116	viability after 12 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.4215740605275866	[350]	[113,168,132]	-4	hSpCas9	negative selection	2064252
77636911	77636934	5	+	26627737	HCT116	viability after 12 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-0.3105466269383337	[106]	[37,58,39]	-3	hSpCas9	negative selection	2064253
77637034	77637057	5	+	26627737	HCT116	viability after 12 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.03562227048131006	[151]	[40,113,94]	0	hSpCas9	negative selection	2064254
77638499	77638522	5	+	26627737	HCT116	viability after 12 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.41280111046343426	[223]	[161,169,137]	4	hSpCas9	negative selection	2064255
77638510	77638533	5	+	26627737	HCT116	viability after 12 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	0.6535024215830141	[85]	[44,88,81]	6	hSpCas9	negative selection	2064256
77630460	77630483	5	-	26627737	HCT116	viability after 15 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-1.0955738749951784	[133]	[20,31,52]	-8	hSpCas9	negative selection	2146566
77630528	77630551	5	+	26627737	HCT116	viability after 15 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.4204491052334321	[350]	[161,203,87]	-4	hSpCas9	negative selection	2146567
77636911	77636934	5	+	26627737	HCT116	viability after 15 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-0.21235400249853353	[106]	[14,128,10]	-2	hSpCas9	negative selection	2146568
77637034	77637057	5	+	26627737	HCT116	viability after 15 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	-0.08714049368414645	[151]	[118,48,82]	-1	hSpCas9	negative selection	2146569
77638499	77638522	5	+	26627737	HCT116	viability after 15 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.552874526178424	[223]	[202,184,179]	5	hSpCas9	negative selection	2146570
77638510	77638533	5	+	26627737	HCT116	viability after 15 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	1.1271302083504147	[85]	[112,81,128]	8	hSpCas9	negative selection	2146571
77630460	77630483	5	-	26627737	HCT116	viability after 18 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-1.3651039228470543	[133]	[4,2,70]	-8	hSpCas9	negative selection	2228881
77630528	77630551	5	+	26627737	HCT116	viability after 18 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.021972906166425	[350]	[80,239,175]	0	hSpCas9	negative selection	2228882
77636911	77636934	5	+	26627737	HCT116	viability after 18 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	0.3395879310995362	[106]	[30,39,129]	3	hSpCas9	negative selection	2228883
77637034	77637057	5	+	26627737	HCT116	viability after 18 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	-0.8495745259577365	[151]	[29,30,62]	-7	hSpCas9	negative selection	2228884
77638499	77638522	5	+	26627737	HCT116	viability after 18 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.7843725508327166	[223]	[102,216,239]	6	hSpCas9	negative selection	2228885
77638510	77638533	5	+	26627737	HCT116	viability after 18 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	0.9942808240322893	[85]	[98,45,106]	7	hSpCas9	negative selection	2228886
77637173	77637196	5	-	24336569	HL60	viability	GAGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	0.009827578827109607	[818]	[1744]	0	hSpCas9	negative selection	2282302
77637178	77637201	5	-	24336569	HL60	viability	ACCGGGAGGCGGTGAAGTGTAGG	OTP	ENSG00000171540	-1.5516061993481944	[506]	[365]	-8	hSpCas9	negative selection	2282303
77637189	77637212	5	-	24336569	HL60	viability	GCTTCTGGGCCACCGGGAGGCGG	OTP	ENSG00000171540	0.6098503812645938	[304]	[984]	5	hSpCas9	negative selection	2282304
77637195	77637218	5	-	24336569	HL60	viability	CGCCGAGCTTCTGGGCCACCGGG	OTP	ENSG00000171540	1.77070635017847	[162]	[1176]	9	hSpCas9	negative selection	2282305
77637203	77637226	5	-	24336569	HL60	viability	AAAGATGCCGCCGAGCTTCTGGG	OTP	ENSG00000171540	2.760551828875325	[93]	[1347]	9	hSpCas9	negative selection	2282306
77638499	77638522	5	+	24336569	HL60	viability	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.41118365010858027	[483]	[1361]	4	hSpCas9	negative selection	2282307
77638507	77638530	5	+	24336569	HL60	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	0.2722934756188238	[519]	[1328]	2	hSpCas9	negative selection	2282308
77638512	77638535	5	-	24336569	HL60	viability	GACCTCCTGGACGCCAGGCTAGG	OTP	ENSG00000171540	0.20116511543546345	[907]	[2208]	2	hSpCas9	negative selection	2282309
77638517	77638540	5	-	24336569	HL60	viability	ATGCCGACCTCCTGGACGCCAGG	OTP	ENSG00000171540	1.3738886489049529	[160]	[882]	8	hSpCas9	negative selection	2282310
77638525	77638548	5	-	24336569	HL60	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	-0.21302380486217384	[544]	[994]	-2	hSpCas9	negative selection	2282311
77637173	77637196	5	-	24336569	KBM7	viability	GAGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	0.020820619060706647	[553]	[1532]	0	hSpCas9	negative selection	2349479
77637178	77637201	5	-	24336569	KBM7	viability	ACCGGGAGGCGGTGAAGTGTAGG	OTP	ENSG00000171540	0.521841128696304	[297]	[1166]	5	hSpCas9	negative selection	2349480
77637189	77637212	5	-	24336569	KBM7	viability	GCTTCTGGGCCACCGGGAGGCGG	OTP	ENSG00000171540	0.9796377972232451	[316]	[1704]	8	hSpCas9	negative selection	2349481
77637195	77637218	5	-	24336569	KBM7	viability	CGCCGAGCTTCTGGGCCACCGGG	OTP	ENSG00000171540	1.2234310447295689	[159]	[1018]	8	hSpCas9	negative selection	2349482
77637203	77637226	5	-	24336569	KBM7	viability	AAAGATGCCGCCGAGCTTCTGGG	OTP	ENSG00000171540	0.13164693462312926	[251]	[752]	1	hSpCas9	negative selection	2349483
77638499	77638522	5	+	24336569	KBM7	viability	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.6893856061190312	[486]	[2141]	6	hSpCas9	negative selection	2349484
77638507	77638530	5	+	24336569	KBM7	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.0762876272404934	[338]	[876]	0	hSpCas9	negative selection	2349485
77638512	77638535	5	-	24336569	KBM7	viability	GACCTCCTGGACGCCAGGCTAGG	OTP	ENSG00000171540	-0.4436800183891997	[738]	[1481]	-4	hSpCas9	negative selection	2349486
77638517	77638540	5	-	24336569	KBM7	viability	ATGCCGACCTCCTGGACGCCAGG	OTP	ENSG00000171540	1.3755430413670382	[129]	[919]	9	hSpCas9	negative selection	2349487
77638525	77638548	5	-	24336569	KBM7	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	-0.4527532428868196	[418]	[834]	-4	hSpCas9	negative selection	2349488
77638793	77638816	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCCTGCAAATGTCAGCGCCCGG	OTP	ENSG00000171540	-1.433957893578556	[181,166]	[19,6]	-8	dCas9-VP64	positive selection	2459117
77638832	77638855	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGGCGCAGGCGAGCGGGCGGG	OTP	ENSG00000171540	1.7427444226727657	[56,12]	[1,51]	6	dCas9-VP64	positive selection	2459118
77638811	77638834	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGGAGTGGGGGACTCTCCGGG	OTP	ENSG00000171540	-0.7397115833303676	[41,8]	[3,1]	-4	dCas9-VP64	positive selection	2459119
77638793	77638816	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCCTGCAAATGTCAGCGCCCGG	OTP	ENSG00000171540	-0.24819791481814724	[65,58]	[15,16]	-2	dCas9-VP64	positive selection	2554372
77638832	77638855	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGGCGCAGGCGAGCGGGCGGG	OTP	ENSG00000171540	-0.5127780817473454	[20,182]	[9,34]	-5	dCas9-VP64	positive selection	2554373
77638811	77638834	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGGAGTGGGGGACTCTCCGGG	OTP	ENSG00000171540	-0.045049859570950423	[22,144]	[4,45]	0	dCas9-VP64	positive selection	2554374
77636911	77636934	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	-0.2929558199328057	[2,2]	[2,0]	-4	hSpCas9	positive selection	3009113
77636863	77636886	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCACGCATAAAGATGTCGGGG	OTP	ENSG00000171540	0.25426564669926727	[3,3]	[4,3]	5	hSpCas9	positive selection	3009114
77637192	77637215	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	-0.11922660020342842	[4,3]	[3,2]	-2	hSpCas9	positive selection	3009115
77637136	77637159	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCCCCCGGATGGCCCCCGGGG	OTP	ENSG00000171540	-0.000699540930181819	[2,2]	[2,1]	0	hSpCas9	positive selection	3009116
77636911	77636934	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.4343925224213664	[2,2]	[1,2]	7	hSpCas9	positive selection	3076971
77636863	77636886	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCACGCATAAAGATGTCGGGG	OTP	ENSG00000171540	0.34634933272811996	[3,3]	[4,2]	6	hSpCas9	positive selection	3076972
77637192	77637215	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	0.42992134422176914	[4,4]	[4,4]	7	hSpCas9	positive selection	3076973
77637136	77637159	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCCCCCGGATGGCCCCCGGGG	OTP	ENSG00000171540	0.023886911484709505	[2,2]	[0,1]	0	hSpCas9	positive selection	3076974
77630724	77630747		-	24336571	A375	resistance to PLX after 7 days	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	-0.3605449412991373	[19,15]	[12,13]	-8	hSpCas9	positive selection	3133483
77637204	77637227		-	24336571	A375	resistance to PLX after 7 days	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-0.269475434731107	[10,11]	[7,10]	-7	hSpCas9	positive selection	3133484
77630615	77630638		-	24336571	A375	resistance to PLX after 7 days	TCCACGCCAACGACACCCGCTGG	OTP	ENSG00000171540	-0.10037603884117208	[20,21]	[17,22]	-3	hSpCas9	positive selection	3133485
77637034	77637057		+	24336571	A375	resistance to PLX after 7 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	-0.32484203019214863	[10,10]	[7,8]	-8	hSpCas9	positive selection	3133486
77630724	77630747		-	24336571	A375	resistance to PLX after 14 days	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	-0.9811465601710694	[22,13]	[3,3]	-9	hSpCas9	positive selection	3191276
77637204	77637227		-	24336571	A375	resistance to PLX after 14 days	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-0.7924797209114145	[14,12]	[2,3]	-8	hSpCas9	positive selection	3191277
77630615	77630638		-	24336571	A375	resistance to PLX after 14 days	TCCACGCCAACGACACCCGCTGG	OTP	ENSG00000171540	-0.22038402351224412	[13,19]	[5,6]	-2	hSpCas9	positive selection	3191278
77637034	77637057		+	24336571	A375	resistance to PLX after 14 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.05760398487416574	[5,6]	[2,2]	0	hSpCas9	positive selection	3191279
77630724	77630747		-	24336571	A375	viability after 7 days	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.46203102181070504	[13]	[19,15]	7	hSpCas9	negative selection	3249069
77637204	77637227		-	24336571	A375	viability after 7 days	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.17187122069554614	[10]	[10,11]	2	hSpCas9	negative selection	3249070
77630615	77630638		-	24336571	A375	viability after 7 days	TCCACGCCAACGACACCCGCTGG	OTP	ENSG00000171540	0.04199369199364478	[21]	[20,21]	0	hSpCas9	negative selection	3249071
77637034	77637057		+	24336571	A375	viability after 7 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.8287823178181016	[5]	[10,10]	9	hSpCas9	negative selection	3249072
77630724	77630747		-	24336571	A375	viability after 14 days	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.5187305159687268	[13]	[22,13]	6	hSpCas9	negative selection	3306862
77637204	77637227		-	24336571	A375	viability after 14 days	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.46884814368914224	[10]	[14,12]	6	hSpCas9	negative selection	3306863
77630615	77630638		-	24336571	A375	viability after 14 days	TCCACGCCAACGACACCCGCTGG	OTP	ENSG00000171540	-0.284362258446436	[21]	[13,19]	-3	hSpCas9	negative selection	3306864
77637034	77637057		+	24336571	A375	viability after 14 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.17361141129599067	[5]	[5,6]	2	hSpCas9	negative selection	3306865
77630460	77630483	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	2.4499712893882313	[27,27]	[0,0]	8	hSpCas9	positive selection	3384265
77638507	77638530	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.19388490038649384	[174,174]	[0,0]	-1	hSpCas9	positive selection	3384266
77638525	77638548	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	-0.3425866307412928	[193,193]	[0,0]	-2	hSpCas9	positive selection	3384267
77636910	77636933	5	+	26780180	HT29	viability (Avana library 4 designs)	CCAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.90082699004024	[]	[]	3	hSpCas9	negative selection	3447124
77636862	77636885	5	+	26780180	HT29	viability (Avana library 4 designs)	CCTCACGCATAAAGATGTCGGGG	OTP	ENSG00000171540	0.839919684985628	[]	[]	3	hSpCas9	negative selection	3447125
77637192	77637215	5	-	26780180	HT29	viability (Avana library 4 designs)	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	0.968439235994305	[]	[]	4	hSpCas9	negative selection	3447126
77637135	77637158	5	+	26780180	HT29	viability (Avana library 4 designs)	GGTCCCCCGGATGGCCCCCGGGG	OTP	ENSG00000171540	0.718819121066244	[]	[]	2	hSpCas9	negative selection	3447127
77637135	77637158	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCCCCCGGATGGCCCCCGGGG	OTP	ENSG00000171540	5.68550757118711	[]	[]	8	hSpCas9	negative selection	3540779
77636862	77636885	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCACGCATAAAGATGTCGGGG	OTP	ENSG00000171540	0.632163748495155	[]	[]	0	hSpCas9	negative selection	3540780
77636910	77636933	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	6.15452019897792	[]	[]	9	hSpCas9	negative selection	3540781
77637192	77637215	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	5.40531673975903	[]	[]	8	hSpCas9	negative selection	3540782
77638510	77638533	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	-0.731669974196591	[]	[]	-1	hSpCas9	negative selection	3540783
77637107	77637130	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCCAACTCTGACCCAGTGGAGGG	OTP	ENSG00000171540	3.83520153716565	[]	[]	6	hSpCas9	negative selection	3540784
77637135	77637158	5	+	26780180	A375	viability (Avana lentiGuide)	GGTCCCCCGGATGGCCCCCGGGG	OTP	ENSG00000171540	2.8210193969457	[]	[]	3	hSpCas9	negative selection	3649438
77636862	77636885	5	+	26780180	A375	viability (Avana lentiGuide)	CCTCACGCATAAAGATGTCGGGG	OTP	ENSG00000171540	5.82045275616075	[]	[]	5	hSpCas9	negative selection	3649439
77636910	77636933	5	+	26780180	A375	viability (Avana lentiGuide)	CCAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	-7.00262613736889	[]	[]	-9	hSpCas9	negative selection	3649440
77637192	77637215	5	-	26780180	A375	viability (Avana lentiGuide)	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	3.74347187993606	[]	[]	3	hSpCas9	negative selection	3649441
77638510	77638533	5	+	26780180	A375	viability (Avana lentiGuide)	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	0.291475171643069	[]	[]	0	hSpCas9	negative selection	3649442
77637107	77637130	5	-	26780180	A375	viability (Avana lentiGuide)	CCCAACTCTGACCCAGTGGAGGG	OTP	ENSG00000171540	-5.58538583282992	[]	[]	-8	hSpCas9	negative selection	3649443
77637135	77637158	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCCCCCGGATGGCCCCCGGGG	OTP	ENSG00000171540	0.3595904153244175	[2]	[4,3]	9	hSpCas9	positive selection	3758097
77636862	77636885	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCACGCATAAAGATGTCGGGG	OTP	ENSG00000171540	-0.17513191553054958	[5]	[4,4]	-3	hSpCas9	positive selection	3758098
77636910	77636933	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.28643758791595325	[3]	[5,4]	8	hSpCas9	positive selection	3758099
77637192	77637215	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	0.3154104113409939	[5]	[6,6]	8	hSpCas9	positive selection	3758100
77638510	77638533	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	0.09904949047514755	[4]	[4,3]	2	hSpCas9	positive selection	3758101
77637107	77637130	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCCAACTCTGACCCAGTGGAGGG	OTP	ENSG00000171540	0.3831081090316766	[4]	[5,5]	9	hSpCas9	positive selection	3758102
77637135	77637158	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCCCCCGGATGGCCCCCGGGG	OTP	ENSG00000171540	-0.6009237827855806	[3]	[1,1]	-6	hSpCas9	positive selection	3866704
77636862	77636885	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCACGCATAAAGATGTCGGGG	OTP	ENSG00000171540	-0.6866164600373865	[6]	[5,0]	-7	hSpCas9	positive selection	3866705
77636910	77636933	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.16556969685604878	[3]	[4,2]	4	hSpCas9	positive selection	3866706
77637192	77637215	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	0.0808551925444815	[5]	[4,5]	1	hSpCas9	positive selection	3866707
77638510	77638533	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	0.017642294771438652	[5]	[4,5]	0	hSpCas9	positive selection	3866708
77637107	77637130	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCCAACTCTGACCCAGTGGAGGG	OTP	ENSG00000171540	0.34051495745176835	[4]	[5,5]	8	hSpCas9	positive selection	3866709
77630460	77630483	5	-	26780180	A375	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.668553484270324	[]	[]	2	hSpCas9	negative selection	3977615
77630724	77630747	5	-	26780180	A375	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.455967530800883	[]	[]	1	hSpCas9	negative selection	3977616
77638507	77638530	5	+	26780180	A375	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	1.22825826521486	[]	[]	6	hSpCas9	negative selection	3977617
77637204	77637227	5	-	26780180	A375	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.16061205234758	[]	[]	0	hSpCas9	negative selection	3977618
77638525	77638548	5	-	26780180	A375	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.468591376503468	[]	[]	1	hSpCas9	negative selection	3977619
77637034	77637057	5	+	26780180	A375	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.995103508382675	[]	[]	4	hSpCas9	negative selection	3977620
77630460	77630483	5	-	26780180	HT29	viability (GeCKOv2 library)	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.816506843960665	[]	[]	3	hSpCas9	negative selection	4085581
77630724	77630747	5	-	26780180	HT29	viability (GeCKOv2 library)	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.57584502719993	[]	[]	2	hSpCas9	negative selection	4085582
77638507	77638530	5	+	26780180	HT29	viability (GeCKOv2 library)	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	1.12661587464541	[]	[]	5	hSpCas9	negative selection	4085583
77637204	77637227	5	-	26780180	HT29	viability (GeCKOv2 library)	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.25018857526148	[]	[]	0	hSpCas9	negative selection	4085584
77638525	77638548	5	-	26780180	HT29	viability (GeCKOv2 library)	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	1.58208713153196	[]	[]	8	hSpCas9	negative selection	4085585
77637034	77637057	5	+	26780180	HT29	viability (GeCKOv2 library)	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.343442755389505	[]	[]	0	hSpCas9	negative selection	4085586
77630724	77630747	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	-0.3679263601858589	[3]	[1,1]	-7	hSpCas9	positive selection	4158311
77637204	77637227	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-0.21598026558265368	[3]	[2,1]	-5	hSpCas9	positive selection	4158312
77630615	77630638	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCACGCCAACGACACCCGCTGG	OTP	ENSG00000171540	0.030463714753622265	[3]	[2,2]	0	hSpCas9	positive selection	4158313
77637034	77637057	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	-0.36363883262897156	[3]	[1,1]	-7	hSpCas9	positive selection	4158314
77630724	77630747	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.020744090359609575	[3]	[2,2,1,0]	0	hSpCas9	positive selection	4222333
77637204	77637227	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.0029433753546669883	[2]	[0,1,1,0]	0	hSpCas9	positive selection	4222334
77630615	77630638	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCACGCCAACGACACCCGCTGG	OTP	ENSG00000171540	-0.2717997529547708	[4]	[2,0,2,0]	-4	hSpCas9	positive selection	4222335
77637034	77637057	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.10946305220213093	[3]	[3,3,0,0]	0	hSpCas9	positive selection	4222336
77637204	77637227	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.3706494322623428	[0]	[0,0]	7	hSpCas9	positive selection	4288399
77637034	77637057	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.42896112679686405	[2]	[3,2]	8	hSpCas9	positive selection	4288400
77630724	77630747	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	-0.06496411263780494	[1]	[1,0]	-1	hSpCas9	positive selection	4288401
77630460	77630483	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.20965030153459696	[1]	[0,1]	4	hSpCas9	positive selection	4352652
77638507	77638530	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.04130070190827001	[3]	[2,2]	-1	hSpCas9	positive selection	4352653
77638525	77638548	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.5228465111741399	[2]	[2,3]	9	hSpCas9	positive selection	4352654
77630614	77630636	5	-	27760321	OCIAML3	viability	CACGCCAACGACACCCGCTGGG	OTP	ENSG00000171540	0.5594658940575876	[1370,1121]	[1469,1376]	6	hSpCas9	negative selection	4424953
77630691	77630713	5	+	27760321	OCIAML3	viability	AACTGAGGCAGGCCTGGCGTGG	OTP	ENSG00000171540	-0.020187577476494023	[767,719]	[449,735]	0	hSpCas9	negative selection	4424954
77636911	77636933	5	+	27760321	OCIAML3	viability	CAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	-0.26669006111623883	[704,552]	[390,425]	-3	hSpCas9	negative selection	4424955
77637068	77637090	5	-	27760321	OCIAML3	viability	GGGAGGACATCACCACAGTGGG	OTP	ENSG00000171540	0.26555528801000283	[495,424]	[382,494]	3	hSpCas9	negative selection	4424956
77637173	77637195	5	-	27760321	OCIAML3	viability	AGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	0.04836905863795593	[539,625]	[415,553]	0	hSpCas9	negative selection	4424957
77630614	77630636	5	-	27760321	OCIAML2	viability	CACGCCAACGACACCCGCTGGG	OTP	ENSG00000171540	0.32631639173488236	[1370,1121]	[1223,1302]	4	hSpCas9	negative selection	4508416
77630691	77630713	5	+	27760321	OCIAML2	viability	AACTGAGGCAGGCCTGGCGTGG	OTP	ENSG00000171540	-0.28827991513700935	[767,719]	[405,607]	-4	hSpCas9	negative selection	4508417
77636911	77636933	5	+	27760321	OCIAML2	viability	CAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.1389461525823691	[704,552]	[515,609]	1	hSpCas9	negative selection	4508418
77637068	77637090	5	-	27760321	OCIAML2	viability	GGGAGGACATCACCACAGTGGG	OTP	ENSG00000171540	0.2460783471607129	[495,424]	[351,556]	3	hSpCas9	negative selection	4508419
77637173	77637195	5	-	27760321	OCIAML2	viability	AGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	0.18244015857566126	[539,625]	[531,550]	2	hSpCas9	negative selection	4508420
77630614	77630636	5	-	27760321	MV411	viability	CACGCCAACGACACCCGCTGGG	OTP	ENSG00000171540	1.214375425289494	[1370,1121]	[1784,2070]	8	hSpCas9	negative selection	4591879
77630691	77630713	5	+	27760321	MV411	viability	AACTGAGGCAGGCCTGGCGTGG	OTP	ENSG00000171540	0.41628249602851986	[767,719]	[659,648]	3	hSpCas9	negative selection	4591880
77636911	77636933	5	+	27760321	MV411	viability	CAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	-0.0073960079786521415	[704,552]	[428,381]	0	hSpCas9	negative selection	4591881
77637068	77637090	5	-	27760321	MV411	viability	GGGAGGACATCACCACAGTGGG	OTP	ENSG00000171540	-0.11611758529535633	[495,424]	[195,404]	-1	hSpCas9	negative selection	4591882
77637173	77637195	5	-	27760321	MV411	viability	AGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	0.313859347361021	[539,625]	[345,687]	2	hSpCas9	negative selection	4591883
77630614	77630636	5	-	27760321	HL60	viability	CACGCCAACGACACCCGCTGGG	OTP	ENSG00000171540	0.3493027811712899	[1370,1121]	[1101,1490]	4	hSpCas9	negative selection	4675342
77630691	77630713	5	+	27760321	HL60	viability	AACTGAGGCAGGCCTGGCGTGG	OTP	ENSG00000171540	0.298788112843011	[767,719]	[667,832]	3	hSpCas9	negative selection	4675343
77636911	77636933	5	+	27760321	HL60	viability	CAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.3685750178141378	[704,552]	[624,694]	4	hSpCas9	negative selection	4675344
77637068	77637090	5	-	27760321	HL60	viability	GGGAGGACATCACCACAGTGGG	OTP	ENSG00000171540	-0.22194096761117468	[495,424]	[256,389]	-3	hSpCas9	negative selection	4675345
77637173	77637195	5	-	27760321	HL60	viability	AGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	0.6784276298372254	[539,625]	[811,723]	7	hSpCas9	negative selection	4675346
77630614	77630636	5	-	27760321	HT1080	viability	CACGCCAACGACACCCGCTGGG	OTP	ENSG00000171540	0.42743986400931644	[1121,875]	[560,506]	2	hSpCas9	negative selection	4758805
77630691	77630713	5	+	27760321	HT1080	viability	AACTGAGGCAGGCCTGGCGTGG	OTP	ENSG00000171540	-2.3730724181156164	[719,561]	[65,30]	-6	hSpCas9	negative selection	4758806
77636911	77636933	5	+	27760321	HT1080	viability	CAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.5971415890590199	[552,431]	[355,231]	3	hSpCas9	negative selection	4758807
77637068	77637090	5	-	27760321	HT1080	viability	GGGAGGACATCACCACAGTGGG	OTP	ENSG00000171540	1.0430793272434482	[424,331]	[462,143]	5	hSpCas9	negative selection	4758808
77637173	77637195	5	-	27760321	HT1080	viability	AGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	1.50542652495456	[625,488]	[884,351]	8	hSpCas9	negative selection	4758809
77630614	77630636	5	-	27760321	HT29	viability after 7 days	CACGCCAACGACACCCGCTGGG	OTP	ENSG00000171540	0.763688145994164	[1121,875]	[2260,2120,2168]	9	hSpCas9	negative selection	4842268
77630691	77630713	5	+	27760321	HT29	viability after 7 days	AACTGAGGCAGGCCTGGCGTGG	OTP	ENSG00000171540	0.3275860006621648	[719,561]	[1071,1108,928]	5	hSpCas9	negative selection	4842269
77636911	77636933	5	+	27760321	HT29	viability after 7 days	CAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	-0.1279160739648883	[552,431]	[747,505,509]	-2	hSpCas9	negative selection	4842270
77637068	77637090	5	-	27760321	HT29	viability after 7 days	GGGAGGACATCACCACAGTGGG	OTP	ENSG00000171540	0.06343248199401692	[424,331]	[552,493,484]	1	hSpCas9	negative selection	4842271
77637173	77637195	5	-	27760321	HT29	viability after 7 days	AGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	0.33964419579163485	[625,488]	[1050,829,860]	5	hSpCas9	negative selection	4842272
77630614	77630636	5	-	27760321	HT29	viability after 25 days	CACGCCAACGACACCCGCTGGG	OTP	ENSG00000171540	0.8782173214577393	[1121,875]	[2222,1434,2687]	8	hSpCas9	negative selection	4925731
77630691	77630713	5	+	27760321	HT29	viability after 25 days	AACTGAGGCAGGCCTGGCGTGG	OTP	ENSG00000171540	-0.5921378839255759	[719,561]	[384,630,442]	-5	hSpCas9	negative selection	4925732
77636911	77636933	5	+	27760321	HT29	viability after 25 days	CAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.36586310093734237	[552,431]	[418,646,1174]	4	hSpCas9	negative selection	4925733
77637068	77637090	5	-	27760321	HT29	viability after 25 days	GGGAGGACATCACCACAGTGGG	OTP	ENSG00000171540	0.20322397632212574	[424,331]	[521,469,499]	2	hSpCas9	negative selection	4925734
77637173	77637195	5	-	27760321	HT29	viability after 25 days	AGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	0.04263979946159224	[625,488]	[489,644,864]	0	hSpCas9	negative selection	4925735
77630614	77630636	5	-	27760321	HT29	viability after 22 days	CACGCCAACGACACCCGCTGGG	OTP	ENSG00000171540	0.728406037671459	[1121,875]	[1781,1725,2238]	7	hSpCas9	negative selection	5009194
77630691	77630713	5	+	27760321	HT29	viability after 22 days	AACTGAGGCAGGCCTGGCGTGG	OTP	ENSG00000171540	-0.8684719687456637	[719,561]	[306,434,478]	-6	hSpCas9	negative selection	5009195
77636911	77636933	5	+	27760321	HT29	viability after 22 days	CAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.5942381157266432	[552,431]	[689,857,1036]	6	hSpCas9	negative selection	5009196
77637068	77637090	5	-	27760321	HT29	viability after 22 days	GGGAGGACATCACCACAGTGGG	OTP	ENSG00000171540	0.5661508327423983	[424,331]	[722,631,585]	6	hSpCas9	negative selection	5009197
77637173	77637195	5	-	27760321	HT29	viability after 22 days	AGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	0.17302547920935818	[625,488]	[740,874,561]	1	hSpCas9	negative selection	5009198
77630614	77630636	5	-	27760321	HT29	viability after 19 days	CACGCCAACGACACCCGCTGGG	OTP	ENSG00000171540	0.5287296224484828	[1121,875]	[1703,1364,1871]	5	hSpCas9	negative selection	5092657
77630691	77630713	5	+	27760321	HT29	viability after 19 days	AACTGAGGCAGGCCTGGCGTGG	OTP	ENSG00000171540	-0.3732876855671922	[719,561]	[724,632,363]	-3	hSpCas9	negative selection	5092658
77636911	77636933	5	+	27760321	HT29	viability after 19 days	CAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.0025216315379711918	[552,431]	[605,584,507]	0	hSpCas9	negative selection	5092659
77637068	77637090	5	-	27760321	HT29	viability after 19 days	GGGAGGACATCACCACAGTGGG	OTP	ENSG00000171540	0.6012866352360791	[424,331]	[666,864,446]	6	hSpCas9	negative selection	5092660
77637173	77637195	5	-	27760321	HT29	viability after 19 days	AGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	0.4112233002737773	[625,488]	[816,660,1053]	4	hSpCas9	negative selection	5092661
77630614	77630636	5	-	27760321	HT29	viability after 16 days	CACGCCAACGACACCCGCTGGG	OTP	ENSG00000171540	0.6343521141146162	[1121,875]	[1840,1719,1653]	7	hSpCas9	negative selection	5176120
77630691	77630713	5	+	27760321	HT29	viability after 16 days	AACTGAGGCAGGCCTGGCGTGG	OTP	ENSG00000171540	-1.0970036809309727	[719,561]	[396,241,374]	-7	hSpCas9	negative selection	5176121
77636911	77636933	5	+	27760321	HT29	viability after 16 days	CAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.3983568192918269	[552,431]	[556,868,732]	4	hSpCas9	negative selection	5176122
77637068	77637090	5	-	27760321	HT29	viability after 16 days	GGGAGGACATCACCACAGTGGG	OTP	ENSG00000171540	0.4327869597576312	[424,331]	[601,483,633]	5	hSpCas9	negative selection	5176123
77637173	77637195	5	-	27760321	HT29	viability after 16 days	AGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	0.20163777424838225	[625,488]	[767,589,801]	2	hSpCas9	negative selection	5176124
77630614	77630636	5	-	27760321	HT29	viability after 13 days	CACGCCAACGACACCCGCTGGG	OTP	ENSG00000171540	0.5747425594398794	[1121,875]	[1812,1467,1886]	7	hSpCas9	negative selection	5259583
77630691	77630713	5	+	27760321	HT29	viability after 13 days	AACTGAGGCAGGCCTGGCGTGG	OTP	ENSG00000171540	-0.424836253353088	[719,561]	[360,794,508]	-5	hSpCas9	negative selection	5259584
77636911	77636933	5	+	27760321	HT29	viability after 13 days	CAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.15973729453265922	[552,431]	[485,686,735]	2	hSpCas9	negative selection	5259585
77637068	77637090	5	-	27760321	HT29	viability after 13 days	GGGAGGACATCACCACAGTGGG	OTP	ENSG00000171540	0.5698579764728815	[424,331]	[533,758,661]	7	hSpCas9	negative selection	5259586
77637173	77637195	5	-	27760321	HT29	viability after 13 days	AGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	0.09701558241486363	[625,488]	[1061,484,536]	1	hSpCas9	negative selection	5259587
77630614	77630636	5	-	27760321	HT29	viability after 10 days	CACGCCAACGACACCCGCTGGG	OTP	ENSG00000171540	0.5139082717304426	[1121,875]	[2035,1767,1543]	7	hSpCas9	negative selection	5343046
77630691	77630713	5	+	27760321	HT29	viability after 10 days	AACTGAGGCAGGCCTGGCGTGG	OTP	ENSG00000171540	-0.3058843683153162	[719,561]	[772,607,561]	-4	hSpCas9	negative selection	5343047
77636911	77636933	5	+	27760321	HT29	viability after 10 days	CAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.4406062958833427	[552,431]	[1171,770,564]	6	hSpCas9	negative selection	5343048
77637068	77637090	5	-	27760321	HT29	viability after 10 days	GGGAGGACATCACCACAGTGGG	OTP	ENSG00000171540	0.25965339701541296	[424,331]	[625,612,461]	3	hSpCas9	negative selection	5343049
77637173	77637195	5	-	27760321	HT29	viability after 10 days	AGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	0.13851328279899233	[625,488]	[697,763,834]	1	hSpCas9	negative selection	5343050
77630614	77630636	5	-	27760321	MOLM13	viability	CACGCCAACGACACCCGCTGGG	OTP	ENSG00000171540	0.5896860445602583	[1370,1121]	[1050,1054]	4	hSpCas9	negative selection	5426509
77630691	77630713	5	+	27760321	MOLM13	viability	AACTGAGGCAGGCCTGGCGTGG	OTP	ENSG00000171540	-1.4447352473328774	[767,719]	[82,214]	-7	hSpCas9	negative selection	5426510
77636911	77636933	5	+	27760321	MOLM13	viability	CAACTCGTTGAGCTGTGCGGGG	OTP	ENSG00000171540	0.34191804763331823	[704,552]	[704,226]	2	hSpCas9	negative selection	5426511
77637068	77637090	5	-	27760321	MOLM13	viability	GGGAGGACATCACCACAGTGGG	OTP	ENSG00000171540	1.768338462084669	[495,424]	[1004,777]	9	hSpCas9	negative selection	5426512
77637173	77637195	5	-	27760321	MOLM13	viability	AGGCGGTGAAGTGTAGGCTGGG	OTP	ENSG00000171540	-0.8028553765094608	[539,625]	[239,147]	-5	hSpCas9	negative selection	5426513
77638427	77638450	5	+	27661255	K562	viability	GGTCGCATTAAGGTAAAATAAGG	OTP	ENSG00000171540	-0.08335987825647695	[1485,1617]	[1244,1102]	-3	dCas9-KRAB	negative selection	5499659
77638322	77638345	5	-	27661255	K562	viability	GGAATATGTAGATCCAAGAAAGG	OTP	ENSG00000171540	0.10317659339349161	[1739,2104]	[1935,1394]	3	dCas9-KRAB	negative selection	5499660
77638716	77638739	5	-	27661255	K562	viability	GCACCTCCCCGTCTCTCTAAAGG	OTP	ENSG00000171540	0.008082527119720684	[513,535]	[442,402]	0	dCas9-KRAB	negative selection	5499661
77637204	77637227	5	-	27260156	BXPC3	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-0.31292355391269044	[10]	[8,12,2,11]	-6	hSpCas9	negative selection	5560859
77637034	77637057	5	+	27260156	BXPC3	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.3274317715942335	[312]	[362,372,458,458]	7	hSpCas9	negative selection	5560860
77630724	77630747	5	-	27260156	BXPC3	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.6884894161239241	[178]	[327,241,280,360]	9	hSpCas9	negative selection	5560861
77630460	77630483	5	-	27260156	BXPC3	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.3795424392799718	[84]	[83,145,103,130]	7	hSpCas9	negative selection	5625112
77638507	77638530	5	+	27260156	BXPC3	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.2653076400021694	[753]	[573,704,638,713]	-6	hSpCas9	negative selection	5625113
77638525	77638548	5	-	27260156	BXPC3	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.10916492552265564	[397]	[318,473,515,503]	2	hSpCas9	negative selection	5625114
77637204	77637227	5	-	27260156	A673	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-0.7447631374918524	[10]	[4,3,2,19]	-9	hSpCas9	negative selection	5682110
77637034	77637057	5	+	27260156	A673	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.5060884582270512	[312]	[584,580,460,510]	9	hSpCas9	negative selection	5682111
77630724	77630747	5	-	27260156	A673	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.5724062593653069	[178]	[335,299,340,301]	9	hSpCas9	negative selection	5682112
77630460	77630483	5	-	27260156	A673	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.29123324705853637	[84]	[72,124,124,172]	6	hSpCas9	negative selection	5746363
77638507	77638530	5	+	27260156	A673	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.3348811872735199	[753]	[712,722,789,637]	-7	hSpCas9	negative selection	5746364
77638525	77638548	5	-	27260156	A673	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.1459660585994953	[397]	[611,458,634,411]	3	hSpCas9	negative selection	5746365
77637204	77637227	5	-	27260156	A375	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.9435845416795265	[10]	[18,13,55,9]	9	hSpCas9	negative selection	5803361
77637034	77637057	5	+	27260156	A375	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.6812963996155303	[312]	[677,780,459,465]	8	hSpCas9	negative selection	5803362
77630724	77630747	5	-	27260156	A375	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.4286873117681711	[178]	[302,409,225,211]	6	hSpCas9	negative selection	5803363
77630460	77630483	5	-	27260156	A375	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.3285153034761441	[84]	[119,107,56,39]	-5	hSpCas9	negative selection	5867614
77638507	77638530	5	+	27260156	A375	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.06223865437890952	[753]	[989,942,945,542]	-1	hSpCas9	negative selection	5867615
77638525	77638548	5	-	27260156	A375	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.335025274646261	[397]	[534,700,593,534]	5	hSpCas9	negative selection	5867616
77637204	77637227	5	-	27260156	COLO741	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.16297775621136878	[10]	[25,5,15]	3	hSpCas9	negative selection	5924612
77637034	77637057	5	+	27260156	COLO741	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.4976785455366248	[312]	[728,449,529]	8	hSpCas9	negative selection	5924613
77630724	77630747	5	-	27260156	COLO741	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.4253821699445569	[178]	[311,327,282]	8	hSpCas9	negative selection	5924614
77630460	77630483	5	-	27260156	COLO741	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.3236761811710682	[84]	[160,146,103]	6	hSpCas9	negative selection	5988865
77638507	77638530	5	+	27260156	COLO741	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.1260073199906776	[753]	[1015,946,707]	-3	hSpCas9	negative selection	5988866
77638525	77638548	5	-	27260156	COLO741	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.1024433855836675	[397]	[474,654,503]	2	hSpCas9	negative selection	5988867
77637204	77637227	5	-	27260156	CAL120	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	1.0710042314403267	[10]	[35,2,47]	9	hSpCas9	negative selection	6045863
77637034	77637057	5	+	27260156	CAL120	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.2796746060265283	[312]	[480,438,498]	4	hSpCas9	negative selection	6045864
77630724	77630747	5	-	27260156	CAL120	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.546473635884372	[178]	[366,339,275]	7	hSpCas9	negative selection	6045865
77630460	77630483	5	-	27260156	CAL120	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.9055963198070054	[84]	[185,66,336]	9	hSpCas9	negative selection	6110116
77638507	77638530	5	+	27260156	CAL120	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.019687892207339797	[753]	[986,1011,788]	0	hSpCas9	negative selection	6110117
77638525	77638548	5	-	27260156	CAL120	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	-0.17940207516309511	[397]	[300,308,676]	-3	hSpCas9	negative selection	6110118
77637204	77637227	5	-	27260156	CADOES1	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-0.822119999251469	[10]	[0,15,4,0]	-8	hSpCas9	negative selection	6167114
77637034	77637057	5	+	27260156	CADOES1	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.4664673093132282	[312]	[331,457,345,475]	7	hSpCas9	negative selection	6167115
77630724	77630747	5	-	27260156	CADOES1	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.7669496602222866	[178]	[307,342,230,249]	9	hSpCas9	negative selection	6167116
77630460	77630483	5	-	27260156	CADOES1	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.09699658281482071	[84]	[109,68,56,58]	-2	hSpCas9	negative selection	6231367
77638507	77638530	5	+	27260156	CADOES1	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.2852037127720036	[753]	[532,580,459,733]	-5	hSpCas9	negative selection	6231368
77638525	77638548	5	-	27260156	CADOES1	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.13196377285303365	[397]	[345,352,453,471]	2	hSpCas9	negative selection	6231369
77637204	77637227	5	-	27260156	EWS502	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-1.0018903328950595	[10]	[13,2,3,0]	-8	hSpCas9	negative selection	6288365
77637034	77637057	5	+	27260156	EWS502	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.5101171157008451	[312]	[625,499,282,453]	8	hSpCas9	negative selection	6288366
77630724	77630747	5	-	27260156	EWS502	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	1.0411119457288416	[178]	[336,362,426,443]	9	hSpCas9	negative selection	6288367
77630460	77630483	5	-	27260156	EWS502	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.21823596019093294	[84]	[60,65,109,74]	-4	hSpCas9	negative selection	6352618
77638507	77638530	5	+	27260156	EWS502	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.17123587851799904	[753]	[607,587,720,951]	-3	hSpCas9	negative selection	6352619
77638525	77638548	5	-	27260156	EWS502	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.5213593018965181	[397]	[467,731,553,679]	8	hSpCas9	negative selection	6352620
77637204	77637227	5	-	27260156	EW8	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-1.062627468776367	[10]	[7,0,0,7]	-9	hSpCas9	negative selection	6409616
77637034	77637057	5	+	27260156	EW8	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.3532649982715428	[312]	[419,339,270,283]	6	hSpCas9	negative selection	6409617
77630724	77630747	5	-	27260156	EW8	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.43946187939080505	[178]	[175,227,221,153]	7	hSpCas9	negative selection	6409618
77630460	77630483	5	-	27260156	EW8	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.01524074901265049	[84]	[88,25,22,143]	0	hSpCas9	negative selection	6473869
77638507	77638530	5	+	27260156	EW8	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.16728238053849653	[753]	[558,600,442,590]	-3	hSpCas9	negative selection	6473870
77638525	77638548	5	-	27260156	EW8	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.08224356809545472	[397]	[328,357,320,358]	1	hSpCas9	negative selection	6473871
77637204	77637227	5	-	27260156	CORL105	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.5282955763798718	[10]	[25,7,13,25]	8	hSpCas9	negative selection	6530867
77637034	77637057	5	+	27260156	CORL105	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.4124976728823973	[312]	[483,424,515,530]	7	hSpCas9	negative selection	6530868
77630724	77630747	5	-	27260156	CORL105	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	1.0650711843446719	[178]	[465,424,407,450]	9	hSpCas9	negative selection	6530869
77630460	77630483	5	-	27260156	CORL105	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.14892924644951044	[84]	[78,75,84,117]	-3	hSpCas9	negative selection	6595120
77638507	77638530	5	+	27260156	CORL105	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.1261242723973761	[753]	[960,723,926,648]	-2	hSpCas9	negative selection	6595121
77638525	77638548	5	-	27260156	CORL105	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.3369311619681219	[397]	[707,569,502,563]	6	hSpCas9	negative selection	6595122
77637204	77637227	5	-	27260156	HS294T	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.6584162648391549	[10]	[5,9,2,7]	8	hSpCas9	negative selection	6652118
77637034	77637057	5	+	27260156	HS294T	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	-0.110253812867398	[312]	[93,121,88,150]	-1	hSpCas9	negative selection	6652119
77630724	77630747	5	-	27260156	HS294T	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.7819963455297241	[178]	[124,100,108,144]	8	hSpCas9	negative selection	6652120
77630460	77630483	5	-	27260156	HS294T	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.6273012072665529	[84]	[53,29,84,30]	7	hSpCas9	negative selection	6716371
77638507	77638530	5	+	27260156	HS294T	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.24432112683474666	[753]	[169,232,179,440]	-3	hSpCas9	negative selection	6716372
77638525	77638548	5	-	27260156	HS294T	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.4137987176279039	[397]	[184,164,160,332]	5	hSpCas9	negative selection	6716373
77637204	77637227	5	-	27260156	HCC44	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.5388902828878281	[10]	[8,10,3,44]	8	hSpCas9	negative selection	6773369
77637034	77637057	5	+	27260156	HCC44	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.45251512295346075	[312]	[618,361,378,581]	7	hSpCas9	negative selection	6773370
77630724	77630747	5	-	27260156	HCC44	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.9100654609975326	[178]	[298,484,496,239]	9	hSpCas9	negative selection	6773371
77630460	77630483	5	-	27260156	HCC44	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.36301823698013136	[84]	[177,138,100,75]	6	hSpCas9	negative selection	6837622
77638507	77638530	5	+	27260156	HCC44	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.20491588903009805	[753]	[890,462,1130,593]	-3	hSpCas9	negative selection	6837623
77638525	77638548	5	-	27260156	HCC44	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.3071690725589048	[397]	[579,500,586,569]	5	hSpCas9	negative selection	6837624
77637204	77637227	5	-	27260156	G402	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-0.2497907944354285	[10]	[0,0,7,31]	-3	hSpCas9	negative selection	6894620
77637034	77637057	5	+	27260156	G402	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	1.038814939728696	[312]	[804,1376,417,582]	9	hSpCas9	negative selection	6894621
77630724	77630747	5	-	27260156	G402	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.9161586323923785	[178]	[218,512,585,311]	9	hSpCas9	negative selection	6894622
77630460	77630483	5	-	27260156	G402	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.5163477664076592	[84]	[104,80,100,10]	-6	hSpCas9	negative selection	6958873
77638507	77638530	5	+	27260156	G402	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.04282265826480769	[753]	[1602,712,725,631]	0	hSpCas9	negative selection	6958874
77638525	77638548	5	-	27260156	G402	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	-0.055508474923850276	[397]	[549,538,315,477]	0	hSpCas9	negative selection	6958875
77637204	77637227	5	-	27260156	L33	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	1.187996090131767	[10]	[4,26,9,13]	9	hSpCas9	negative selection	7015871
77637034	77637057	5	+	27260156	L33	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.017147702046131585	[312]	[287,135,154,399]	0	hSpCas9	negative selection	7015872
77630724	77630747	5	-	27260156	L33	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.7810882130030734	[178]	[223,136,235,298]	9	hSpCas9	negative selection	7015873
77630460	77630483	5	-	27260156	L33	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.10671095585697898	[84]	[117,21,59,47]	-2	hSpCas9	negative selection	7080124
77638507	77638530	5	+	27260156	L33	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.6285498237696717	[753]	[410,227,309,491]	-9	hSpCas9	negative selection	7080125
77638525	77638548	5	-	27260156	L33	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	-0.14125369958381997	[397]	[297,163,239,364]	-3	hSpCas9	negative selection	7080126
77637204	77637227	5	-	27260156	K562	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-1.4672182517549608	[10]	[0,0,0,9]	-9	hSpCas9	negative selection	7137122
77637034	77637057	5	+	27260156	K562	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.8559218614666226	[312]	[558,535,585,351]	9	hSpCas9	negative selection	7137123
77630724	77630747	5	-	27260156	K562	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.5678413072653968	[178]	[349,360,96,157]	7	hSpCas9	negative selection	7137124
77630460	77630483	5	-	27260156	K562	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.2066552564676276	[84]	[127,28,9,93]	-3	hSpCas9	negative selection	7201375
77638507	77638530	5	+	27260156	K562	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.3905699993184011	[753]	[415,376,581,634]	-5	hSpCas9	negative selection	7201376
77638525	77638548	5	-	27260156	K562	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.4270701815594983	[397]	[305,483,919,205]	5	hSpCas9	negative selection	7201377
77637204	77637227	5	-	27260156	HT29	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.03846066178599017	[10]	[3,34,3,12]	0	hSpCas9	negative selection	7258373
77637034	77637057	5	+	27260156	HT29	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.22652094227272762	[312]	[348,452,534,434]	4	hSpCas9	negative selection	7258374
77630724	77630747	5	-	27260156	HT29	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.4693241680342771	[178]	[318,282,284,313]	8	hSpCas9	negative selection	7258375
77630460	77630483	5	-	27260156	HT29	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.0662604569113534	[84]	[107,165,67,62]	-1	hSpCas9	negative selection	7322626
77638507	77638530	5	+	27260156	HT29	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.10892782408715129	[753]	[875,883,811,828]	-2	hSpCas9	negative selection	7322627
77638525	77638548	5	-	27260156	HT29	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	-0.010853075041527577	[397]	[590,551,461,343]	0	hSpCas9	negative selection	7322628
77637204	77637227	5	-	27260156	MHHES1	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.1438806466679985	[10]	[1,34,18,1]	2	hSpCas9	negative selection	7379624
77637034	77637057	5	+	27260156	MHHES1	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.5605250861461263	[312]	[423,402,747,479]	8	hSpCas9	negative selection	7379625
77630724	77630747	5	-	27260156	MHHES1	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.7428855698401235	[178]	[377,348,356,277]	9	hSpCas9	negative selection	7379626
77630460	77630483	5	-	27260156	MHHES1	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.2432708241410424	[84]	[73,240,58,89]	4	hSpCas9	negative selection	7443877
77638507	77638530	5	+	27260156	MHHES1	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.23371554276386486	[753]	[744,993,659,544]	-4	hSpCas9	negative selection	7443878
77638525	77638548	5	-	27260156	MHHES1	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.08027475460814082	[397]	[462,595,382,456]	1	hSpCas9	negative selection	7443879
77637204	77637227	5	-	27260156	MEWO	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-0.3799463961145779	[10]	[3,0,17]	-7	hSpCas9	negative selection	7500875
77637034	77637057	5	+	27260156	MEWO	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.3931482318678583	[312]	[472,329,367]	8	hSpCas9	negative selection	7500876
77630724	77630747	5	-	27260156	MEWO	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.5373092326814068	[178]	[309,248,182]	9	hSpCas9	negative selection	7500877
77630460	77630483	5	-	27260156	MEWO	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.17825031084292053	[84]	[91,76,45]	-4	hSpCas9	negative selection	7565128
77638507	77638530	5	+	27260156	MEWO	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.10798210398127084	[753]	[716,568,689]	-2	hSpCas9	negative selection	7565129
77638525	77638548	5	-	27260156	MEWO	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.17993150451219894	[397]	[612,295,393]	4	hSpCas9	negative selection	7565130
77637204	77637227	5	-	27260156	LNCAPCLONEFGC	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	1.8166570522726984	[10]	[2,91,19,19]	9	hSpCas9	negative selection	7622126
77637034	77637057	5	+	27260156	LNCAPCLONEFGC	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.7157636363656883	[312]	[534,474,469,380]	9	hSpCas9	negative selection	7622127
77630724	77630747	5	-	27260156	LNCAPCLONEFGC	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.20599060781159406	[178]	[204,197,173,167]	3	hSpCas9	negative selection	7622128
77630460	77630483	5	-	27260156	LNCAPCLONEFGC	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.5508316071827672	[84]	[36,62,73,38]	-7	hSpCas9	negative selection	7686379
77638507	77638530	5	+	27260156	LNCAPCLONEFGC	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.027576396850951257	[753]	[623,597,625,830]	0	hSpCas9	negative selection	7686380
77638525	77638548	5	-	27260156	LNCAPCLONEFGC	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.15908022861708127	[397]	[343,265,495,527]	2	hSpCas9	negative selection	7686381
77637204	77637227	5	-	27260156	PANC0327	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-2.933371998836771	[10]	[0,1,0,0]	-9	hSpCas9	negative selection	7743377
77637034	77637057	5	+	27260156	PANC0327	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.13438912312384432	[312]	[384,376,294,160]	2	hSpCas9	negative selection	7743378
77630724	77630747	5	-	27260156	PANC0327	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.4084592260787647	[178]	[299,165,106,283]	6	hSpCas9	negative selection	7743379
77630460	77630483	5	-	27260156	PANC0327	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.3028606422284503	[84]	[145,12,57,40]	-4	hSpCas9	negative selection	7807630
77638507	77638530	5	+	27260156	PANC0327	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.42945517859010357	[753]	[503,336,771,397]	-6	hSpCas9	negative selection	7807631
77638525	77638548	5	-	27260156	PANC0327	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	-0.16137506880162863	[397]	[273,253,347,392]	-2	hSpCas9	negative selection	7807632
77637204	77637227	5	-	27260156	NCIH2009	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.8055240743815011	[10]	[72,7,8]	9	hSpCas9	negative selection	7864628
77637034	77637057	5	+	27260156	NCIH2009	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.7442644116605133	[312]	[973,573,698]	8	hSpCas9	negative selection	7864629
77630724	77630747	5	-	27260156	NCIH2009	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.8848593291621542	[178]	[623,335,458]	9	hSpCas9	negative selection	7864630
77630460	77630483	5	-	27260156	NCIH2009	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.5192992074760858	[84]	[85,85,76]	-6	hSpCas9	negative selection	7928881
77638507	77638530	5	+	27260156	NCIH2009	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.6534514020002743	[753]	[752,754,514]	-7	hSpCas9	negative selection	7928882
77638525	77638548	5	-	27260156	NCIH2009	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.5668599587696469	[397]	[969,802,725]	7	hSpCas9	negative selection	7928883
77637204	77637227	5	-	27260156	NCIH1373	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-0.49228801179558257	[10]	[6,2,20,0]	-5	hSpCas9	negative selection	7985879
77637034	77637057	5	+	27260156	NCIH1373	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	1.2009771586711495	[312]	[1189,275,609,340]	9	hSpCas9	negative selection	7985880
77630724	77630747	5	-	27260156	NCIH1373	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.508638288455517	[178]	[238,305,334,64]	5	hSpCas9	negative selection	7985881
77630460	77630483	5	-	27260156	NCIH1373	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-1.454563075965948	[84]	[67,32,12,7]	-9	hSpCas9	negative selection	8050132
77638507	77638530	5	+	27260156	NCIH1373	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.2683086602015658	[753]	[797,834,607,145]	-3	hSpCas9	negative selection	8050133
77638525	77638548	5	-	27260156	NCIH1373	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.8344394181730983	[397]	[900,512,842,256]	8	hSpCas9	negative selection	8050134
77637204	77637227	5	-	27260156	PATU8902	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	2.0180326117872007	[10]	[170,68,6,6]	9	hSpCas9	negative selection	8107130
77637034	77637057	5	+	27260156	PATU8902	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	1.0543190421775614	[312]	[999,786,965,834]	9	hSpCas9	negative selection	8107131
77630724	77630747	5	-	27260156	PATU8902	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.7396665032828882	[178]	[302,672,277,449]	7	hSpCas9	negative selection	8107132
77630460	77630483	5	-	27260156	PATU8902	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-1.0631699503893697	[84]	[11,61,49,110]	-7	hSpCas9	negative selection	8171383
77638507	77638530	5	+	27260156	PATU8902	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.22144169510332368	[753]	[816,985,1036,696]	-2	hSpCas9	negative selection	8171384
77638525	77638548	5	-	27260156	PATU8902	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.6298022358331953	[397]	[788,1014,867,735]	6	hSpCas9	negative selection	8171385
77637204	77637227	5	-	27260156	PANC1	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	1.0291471954681954	[10]	[1,48,17,14]	9	hSpCas9	negative selection	8228381
77637034	77637057	5	+	27260156	PANC1	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.6439467895135405	[312]	[357,561,532,275]	9	hSpCas9	negative selection	8228382
77630724	77630747	5	-	27260156	PANC1	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.1294713273796706	[178]	[216,152,190,113]	2	hSpCas9	negative selection	8228383
77630460	77630483	5	-	27260156	PANC1	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.37857653709857386	[84]	[49,139,133,68]	6	hSpCas9	negative selection	8292634
77638507	77638530	5	+	27260156	PANC1	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.03317830670637889	[753]	[546,1053,629,414]	0	hSpCas9	negative selection	8292635
77638525	77638548	5	-	27260156	PANC1	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	-0.14297886051495315	[397]	[297,324,326,289]	-2	hSpCas9	negative selection	8292636
77637204	77637227	5	-	27260156	PANC0813	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-0.08426564682357984	[10]	[8,26,10,1]	-1	hSpCas9	negative selection	8349632
77637034	77637057	5	+	27260156	PANC0813	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.4102903082740819	[312]	[535,554,404,462]	6	hSpCas9	negative selection	8349633
77630724	77630747	5	-	27260156	PANC0813	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.8145476774815716	[178]	[435,376,346,326]	9	hSpCas9	negative selection	8349634
77630460	77630483	5	-	27260156	PANC0813	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.5327466520086559	[84]	[184,57,46,282]	8	hSpCas9	negative selection	8413885
77638507	77638530	5	+	27260156	PANC0813	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.6963775221772441	[753]	[770,513,419,502]	-7	hSpCas9	negative selection	8413886
77638525	77638548	5	-	27260156	PANC0813	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.29796705303562165	[397]	[504,487,751,548]	5	hSpCas9	negative selection	8413887
77637204	77637227	5	-	27260156	RDES	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.7861304489266523	[10]	[6,46,25,4]	9	hSpCas9	negative selection	8470883
77637034	77637057	5	+	27260156	RDES	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.5605915755984402	[312]	[489,451,504,700]	8	hSpCas9	negative selection	8470884
77630724	77630747	5	-	27260156	RDES	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.8243787044332854	[178]	[276,413,455,308]	9	hSpCas9	negative selection	8470885
77630460	77630483	5	-	27260156	RDES	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.36161408490817415	[84]	[53,155,206,92]	6	hSpCas9	negative selection	8535136
77638507	77638530	5	+	27260156	RDES	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.09597045249611191	[753]	[613,827,854,994]	-2	hSpCas9	negative selection	8535137
77638525	77638548	5	-	27260156	RDES	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.10979620273282187	[397]	[404,439,637,509]	1	hSpCas9	negative selection	8535138
77637204	77637227	5	-	27260156	PC3	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-0.16006601532011544	[10]	[16,4,10,0]	-4	hSpCas9	negative selection	8592134
77637034	77637057	5	+	27260156	PC3	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.41363667792812453	[312]	[238,514,582,423]	8	hSpCas9	negative selection	8592135
77630724	77630747	5	-	27260156	PC3	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.6911389259851572	[178]	[169,329,406,314]	9	hSpCas9	negative selection	8592136
77630460	77630483	5	-	27260156	PC3	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.2745059219143626	[84]	[27,69,120,95]	-6	hSpCas9	negative selection	8656387
77638507	77638530	5	+	27260156	PC3	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.010032091863632964	[753]	[582,712,1385,527]	0	hSpCas9	negative selection	8656388
77638525	77638548	5	-	27260156	PC3	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.049523764813594495	[397]	[285,306,750,449]	1	hSpCas9	negative selection	8656389
77637204	77637227	5	-	27260156	PATU8988T	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	2.7838021802573554	[10]	[268,3,1,6]	9	hSpCas9	negative selection	8713385
77637034	77637057	5	+	27260156	PATU8988T	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.2331206466667557	[312]	[156,596,342,346]	4	hSpCas9	negative selection	8713386
77630724	77630747	5	-	27260156	PATU8988T	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.8671262551725994	[178]	[302,259,297,402]	9	hSpCas9	negative selection	8713387
77630460	77630483	5	-	27260156	PATU8988T	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.8061783172455059	[84]	[279,125,87,73]	9	hSpCas9	negative selection	8777638
77638507	77638530	5	+	27260156	PATU8988T	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.4630466152866552	[753]	[748,512,417,425]	-6	hSpCas9	negative selection	8777639
77638525	77638548	5	-	27260156	PATU8988T	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.005779182804882349	[397]	[288,572,362,332]	0	hSpCas9	negative selection	8777640
77637204	77637227	5	-	27260156	T47D	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-0.21330581537791904	[10]	[16,10,11,3]	-5	hSpCas9	negative selection	8834636
77637034	77637057	5	+	27260156	T47D	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.4196568652088931	[312]	[442,449,522,538]	8	hSpCas9	negative selection	8834637
77630724	77630747	5	-	27260156	T47D	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.9381908205368091	[178]	[514,285,395,411]	9	hSpCas9	negative selection	8834638
77630460	77630483	5	-	27260156	T47D	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.03312056897605409	[84]	[91,81,76,138]	0	hSpCas9	negative selection	8898889
77638507	77638530	5	+	27260156	T47D	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.31889798677553133	[753]	[769,686,597,766]	-6	hSpCas9	negative selection	8898890
77638525	77638548	5	-	27260156	T47D	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.0763021494137475	[397]	[507,422,544,483]	1	hSpCas9	negative selection	8898891
77637204	77637227	5	-	27260156	SU8686	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.45421779036731014	[10]	[12,25,4,13]	7	hSpCas9	negative selection	8955887
77637034	77637057	5	+	27260156	SU8686	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.5943630267638754	[312]	[464,454,466,488]	8	hSpCas9	negative selection	8955888
77630724	77630747	5	-	27260156	SU8686	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	1.0117301410574835	[178]	[314,362,397,357]	9	hSpCas9	negative selection	8955889
77630460	77630483	5	-	27260156	SU8686	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.7290549997359121	[84]	[125,85,181,179]	9	hSpCas9	negative selection	9020140
77638507	77638530	5	+	27260156	SU8686	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.7234131866490715	[753]	[405,431,512,468]	-8	hSpCas9	negative selection	9020141
77638525	77638548	5	-	27260156	SU8686	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.27878180825481996	[397]	[356,412,551,639]	5	hSpCas9	negative selection	9020142
77637204	77637227	5	-	27260156	SKES1	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-1.155757109361577	[10]	[0,0,5,9]	-9	hSpCas9	negative selection	9077138
77637034	77637057	5	+	27260156	SKES1	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.2621924598135321	[312]	[468,437,250,359]	5	hSpCas9	negative selection	9077139
77630724	77630747	5	-	27260156	SKES1	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.870912672558075	[178]	[404,552,231,170]	9	hSpCas9	negative selection	9077140
77630460	77630483	5	-	27260156	SKES1	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.028642311692836042	[84]	[135,93,83,43]	0	hSpCas9	negative selection	9141391
77638507	77638530	5	+	27260156	SKES1	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.05155119460900115	[753]	[829,838,635,630]	-1	hSpCas9	negative selection	9141392
77638525	77638548	5	-	27260156	SKES1	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.2440741748291935	[397]	[554,530,437,381]	5	hSpCas9	negative selection	9141393
77637204	77637227	5	-	27260156	TOV112D	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-2.604043448347939	[10]	[0,0,3,0]	-9	hSpCas9	negative selection	9198389
77637034	77637057	5	+	27260156	TOV112D	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.4172315519267549	[312]	[279,650,467,322]	7	hSpCas9	negative selection	9198390
77630724	77630747	5	-	27260156	TOV112D	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.4943748472194769	[178]	[167,332,215,303]	8	hSpCas9	negative selection	9198391
77630460	77630483	5	-	27260156	TOV112D	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.09517505472517307	[84]	[103,138,95,38]	1	hSpCas9	negative selection	9262642
77638507	77638530	5	+	27260156	TOV112D	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.1317593105796797	[753]	[635,1061,704,446]	-3	hSpCas9	negative selection	9262643
77638525	77638548	5	-	27260156	TOV112D	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.30244688818733684	[397]	[467,555,267,681]	6	hSpCas9	negative selection	9262644
77637204	77637227	5	-	27260156	TC71	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	-0.15380868180366747	[10]	[6,20,0,13]	-4	hSpCas9	negative selection	9319640
77637034	77637057	5	+	27260156	TC71	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.3022470312159323	[312]	[357,354,449,496]	7	hSpCas9	negative selection	9319641
77630724	77630747	5	-	27260156	TC71	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.8033070910547325	[178]	[248,386,310,398]	9	hSpCas9	negative selection	9319642
77630460	77630483	5	-	27260156	TC71	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.5359767793884271	[84]	[151,91,114,171]	9	hSpCas9	negative selection	9383893
77638507	77638530	5	+	27260156	TC71	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.40372367007221893	[753]	[675,544,553,672]	-8	hSpCas9	negative selection	9383894
77638525	77638548	5	-	27260156	TC71	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.09918473597228519	[397]	[470,459,431,465]	2	hSpCas9	negative selection	9383895
77637204	77637227	5	-	27260156	TC32	viability	GAAAGATGCCGCCGAGCTTCTGG	OTP	ENSG00000171540	0.7876677156485083	[10]	[43,0,10,15]	9	hSpCas9	negative selection	9440891
77637034	77637057	5	+	27260156	TC32	viability	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.41883236570574756	[312]	[371,340,522,354]	7	hSpCas9	negative selection	9440892
77630724	77630747	5	-	27260156	TC32	viability	ACCAACGTGTTCCGTGCGCCCGG	OTP	ENSG00000171540	0.7528435245358278	[178]	[233,238,317,358]	9	hSpCas9	negative selection	9440893
77630460	77630483	5	-	27260156	TC32	viability	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.10128576280134594	[84]	[53,84,52,96]	-2	hSpCas9	negative selection	9505144
77638507	77638530	5	+	27260156	TC32	viability	ACTCACCTAGCCTGGCGTCCAGG	OTP	ENSG00000171540	-0.2312431618900438	[753]	[609,413,797,664]	-4	hSpCas9	negative selection	9505145
77638525	77638548	5	-	27260156	TC32	viability	GCTGTCTCATGCCGACCTCCTGG	OTP	ENSG00000171540	0.4594165798757679	[397]	[490,428,546,603]	7	hSpCas9	negative selection	9505146
77630460	77630483	5	-	27869803	HPAFII	viability after 27 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	1.2944619154998949	[80]	[176,43,NaN]	9	hSpCas9	negative selection	9592630
77630528	77630551	5	+	27869803	HPAFII	viability after 27 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.9255150127478705	[401]	[95,123,NaN]	-6	hSpCas9	negative selection	9592631
77636911	77636934	5	+	27869803	HPAFII	viability after 27 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	0.8072862206579915	[99]	[127,61,NaN]	6	hSpCas9	negative selection	9592632
77637034	77637057	5	+	27869803	HPAFII	viability after 27 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.8956871185863674	[78]	[67,84,NaN]	7	hSpCas9	negative selection	9592633
77638499	77638522	5	+	27869803	HPAFII	viability after 27 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	1.5505840636479145	[185]	[472,130,NaN]	9	hSpCas9	negative selection	9592634
77638510	77638533	5	+	27869803	HPAFII	viability after 27 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	0.7889405028073464	[126]	[194,48,NaN]	6	hSpCas9	negative selection	9592635
77630460	77630483	5	-	27869803	HPAFII	viability after 15 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.22652543267301883	[80]	[136,79,NaN]	2	hSpCas9	negative selection	9675079
77630528	77630551	5	+	27869803	HPAFII	viability after 15 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.6135777298914844	[401]	[327,253,NaN]	-6	hSpCas9	negative selection	9675080
77636911	77636934	5	+	27869803	HPAFII	viability after 15 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	0.8028619336313049	[99]	[287,124,NaN]	8	hSpCas9	negative selection	9675081
77637034	77637057	5	+	27869803	HPAFII	viability after 15 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.7141353831469955	[78]	[150,131,NaN]	7	hSpCas9	negative selection	9675082
77638499	77638522	5	+	27869803	HPAFII	viability after 15 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.47596383933330916	[185]	[417,190,NaN]	5	hSpCas9	negative selection	9675083
77638510	77638533	5	+	27869803	HPAFII	viability after 15 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	-0.5542952064456693	[126]	[79,100,NaN]	-5	hSpCas9	negative selection	9675084
77630460	77630483	5	-	27869803	ASPC1	viability after 36 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	1.8784011121707453	[219]	[497,284,125]	9	hSpCas9	negative selection	9757528
77630528	77630551	5	+	27869803	ASPC1	viability after 36 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	0.16404886006202807	[746]	[163,368,317]	1	hSpCas9	negative selection	9757529
77636911	77636934	5	+	27869803	ASPC1	viability after 36 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-0.07141851810657762	[348]	[126,193,44]	0	hSpCas9	negative selection	9757530
77637034	77637057	5	+	27869803	ASPC1	viability after 36 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.9488414110811028	[167]	[7,83,208]	8	hSpCas9	negative selection	9757531
77638499	77638522	5	+	27869803	ASPC1	viability after 36 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	1.2509507322355702	[347]	[434,187,263]	9	hSpCas9	negative selection	9757532
77638510	77638533	5	+	27869803	ASPC1	viability after 36 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	-1.0723515459523554	[293]	[103,46,10]	-7	hSpCas9	negative selection	9757533
77630460	77630483	5	-	27869803	PATU8988S	viability after 35 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.0715325181294948	[194]	[94,69,NaN]	0	hSpCas9	negative selection	9839977
77630528	77630551	5	+	27869803	PATU8988S	viability after 35 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	0.35426209385775603	[651]	[414,255,NaN]	4	hSpCas9	negative selection	9839978
77636911	77636934	5	+	27869803	PATU8988S	viability after 35 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	1.513853129636233	[271]	[460,163,NaN]	9	hSpCas9	negative selection	9839979
77637034	77637057	5	+	27869803	PATU8988S	viability after 35 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	0.4048533930476612	[164]	[79,95,NaN]	4	hSpCas9	negative selection	9839980
77638499	77638522	5	+	27869803	PATU8988S	viability after 35 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.03213795718588175	[385]	[142,174,NaN]	0	hSpCas9	negative selection	9839981
77638510	77638533	5	+	27869803	PATU8988S	viability after 35 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	0.16557265159471135	[164]	[89,58,NaN]	2	hSpCas9	negative selection	9839982
77630460	77630483	5	-	27869803	PATU8988S	viability after 31 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	-0.42288212717203466	[194]	[57,57,NaN]	-5	hSpCas9	negative selection	9922426
77630528	77630551	5	+	27869803	PATU8988S	viability after 31 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	0.5736328984054953	[651]	[389,382,NaN]	6	hSpCas9	negative selection	9922427
77636911	77636934	5	+	27869803	PATU8988S	viability after 31 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	1.361893957829655	[271]	[287,266,NaN]	9	hSpCas9	negative selection	9922428
77637034	77637057	5	+	27869803	PATU8988S	viability after 31 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	1.030475885746268	[164]	[107,167,NaN]	9	hSpCas9	negative selection	9922429
77638499	77638522	5	+	27869803	PATU8988S	viability after 31 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	0.4506527187630215	[385]	[157,276,NaN]	5	hSpCas9	negative selection	9922430
77638510	77638533	5	+	27869803	PATU8988S	viability after 31 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	0.2748168437251639	[164]	[72,87,NaN]	3	hSpCas9	negative selection	9922431
77630460	77630483	5	-	27869803	HPAFII	viability after 35 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	1.283926217206676	[80]	[152,39,NaN]	8	hSpCas9	negative selection	10004875
77630528	77630551	5	+	27869803	HPAFII	viability after 35 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.8918085518116146	[401]	[56,168,NaN]	-5	hSpCas9	negative selection	10004876
77636911	77636934	5	+	27869803	HPAFII	viability after 35 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-0.27135225124366413	[99]	[48,33,NaN]	-2	hSpCas9	negative selection	10004877
77637034	77637057	5	+	27869803	HPAFII	viability after 35 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	1.0459081619414479	[78]	[51,116,NaN]	7	hSpCas9	negative selection	10004878
77638499	77638522	5	+	27869803	HPAFII	viability after 35 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	1.9950596348068899	[185]	[626,91,NaN]	9	hSpCas9	negative selection	10004879
77638510	77638533	5	+	27869803	HPAFII	viability after 35 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	2.028893034213458	[126]	[426,76,NaN]	9	hSpCas9	negative selection	10004880
77630460	77630483	5	-	27869803	HPAFII	viability after 31 days	AACAGCCTGGCGGGTTCCAACGG	OTP	ENSG00000171540	0.9641510220327943	[80]	[103,71,NaN]	7	hSpCas9	negative selection	10087324
77630528	77630551	5	+	27869803	HPAFII	viability after 31 days	CTGGGACAGCGACTGCGCCATGG	OTP	ENSG00000171540	-0.49356425186931235	[401]	[120,202,NaN]	-3	hSpCas9	negative selection	10087325
77636911	77636934	5	+	27869803	HPAFII	viability after 31 days	CAACTCGTTGAGCTGTGCGGGGG	OTP	ENSG00000171540	-0.0005561243780365377	[99]	[35,77,NaN]	0	hSpCas9	negative selection	10087326
77637034	77637057	5	+	27869803	HPAFII	viability after 31 days	TTTGGCGCTCACCGCCAGCGAGG	OTP	ENSG00000171540	1.4048790497208445	[78]	[103,131,NaN]	9	hSpCas9	negative selection	10087327
77638499	77638522	5	+	27869803	HPAFII	viability after 31 days	AGGCGCGCACTCACCTAGCCTGG	OTP	ENSG00000171540	1.6180070502761537	[185]	[485,139,NaN]	9	hSpCas9	negative selection	10087328
77638510	77638533	5	+	27869803	HPAFII	viability after 31 days	CACCTAGCCTGGCGTCCAGGAGG	OTP	ENSG00000171540	1.8061775505988757	[126]	[455,23,NaN]	9	hSpCas9	negative selection	10087329
77637192	77637215	5	-	28162770	P31FUJ	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	-0.5953722837990867	[53]	[41]	-5	hSpCas9	negative selection	10205498
77637027	77637050	5	-	28162770	P31FUJ	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	-0.7206660170304535	[236]	[168]	-5	hSpCas9	negative selection	10205499
77637180	77637203	5	+	28162770	P31FUJ	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	-0.24121444423057886	[171]	[170]	-2	hSpCas9	negative selection	10205500
77637108	77637131	5	-	28162770	P31FUJ	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.6832294940162031	[450]	[850]	7	hSpCas9	negative selection	10205501
77637069	77637092	5	-	28162770	P31FUJ	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	-0.35589733538632523	[268]	[246]	-3	hSpCas9	negative selection	10205502
77637013	77637036	5	-	28162770	P31FUJ	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.47589566472902234	[267]	[437]	5	hSpCas9	negative selection	10205503
77636973	77636996	5	+	28162770	P31FUJ	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	0.24719073670523528	[113]	[158]	2	hSpCas9	negative selection	10205504
77637167	77637190	5	-	28162770	P31FUJ	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	-0.6333401339981074	[197]	[149]	-5	hSpCas9	negative selection	10205505
77637084	77637107	5	-	28162770	P31FUJ	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	-0.1638548506968872	[142]	[149]	-1	hSpCas9	negative selection	10205506
77637055	77637078	5	+	28162770	P31FUJ	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-2.2384267536082567	[256]	[63]	-8	hSpCas9	negative selection	10205507
77637192	77637215	5	-	28162770	TF1	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	NaN	[NaN]	[78]	1	hSpCas9	negative selection	10374864
77637027	77637050	5	-	28162770	TF1	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	NaN	[NaN]	[290]	1	hSpCas9	negative selection	10374865
77637180	77637203	5	+	28162770	TF1	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10374866
77637108	77637131	5	-	28162770	TF1	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	NaN	[NaN]	[321]	1	hSpCas9	negative selection	10374867
77637069	77637092	5	-	28162770	TF1	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	NaN	[NaN]	[191]	1	hSpCas9	negative selection	10374868
77637013	77637036	5	-	28162770	TF1	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10374869
77636973	77636996	5	+	28162770	TF1	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10374870
77637167	77637190	5	-	28162770	TF1	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	NaN	[NaN]	[231]	1	hSpCas9	negative selection	10374871
77637084	77637107	5	-	28162770	TF1	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	NaN	[NaN]	[206]	1	hSpCas9	negative selection	10374872
77637055	77637078	5	+	28162770	TF1	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10374873
77637192	77637215	5	-	28162770	SKM1	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	0.2775339755289088	[6]	[14]	2	hSpCas9	negative selection	10544230
77637027	77637050	5	-	28162770	SKM1	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	0.4999263968653568	[41]	[104]	5	hSpCas9	negative selection	10544231
77637180	77637203	5	+	28162770	SKM1	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	-0.5832148384348891	[49]	[58]	-4	hSpCas9	negative selection	10544232
77637108	77637131	5	-	28162770	SKM1	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.3743955147814979	[119]	[274]	3	hSpCas9	negative selection	10544233
77637069	77637092	5	-	28162770	SKM1	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	-0.1554254317471972	[62]	[99]	-1	hSpCas9	negative selection	10544234
77637013	77637036	5	-	28162770	SKM1	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.4699543171142978	[106]	[261]	4	hSpCas9	negative selection	10544235
77636973	77636996	5	+	28162770	SKM1	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	0.13069258719963772	[30]	[59]	1	hSpCas9	negative selection	10544236
77637167	77637190	5	-	28162770	SKM1	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	-0.16041791569793676	[54]	[86]	-1	hSpCas9	negative selection	10544237
77637084	77637107	5	-	28162770	SKM1	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	0.25600081397926744	[35]	[75]	2	hSpCas9	negative selection	10544238
77637055	77637078	5	+	28162770	SKM1	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-2.097636140635433	[45]	[18]	-8	hSpCas9	negative selection	10544239
77637192	77637215	5	-	28162770	SKM1	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	0.2775339755289088	[6]	[14]	2	hSpCas9	negative selection	10713596
77637027	77637050	5	-	28162770	SKM1	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	0.4999263968653568	[41]	[104]	5	hSpCas9	negative selection	10713597
77637180	77637203	5	+	28162770	SKM1	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	-0.5832148384348891	[49]	[58]	-4	hSpCas9	negative selection	10713598
77637108	77637131	5	-	28162770	SKM1	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.3743955147814979	[119]	[274]	3	hSpCas9	negative selection	10713599
77637069	77637092	5	-	28162770	SKM1	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	-0.1554254317471972	[62]	[99]	-1	hSpCas9	negative selection	10713600
77637013	77637036	5	-	28162770	SKM1	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.4699543171142978	[106]	[261]	4	hSpCas9	negative selection	10713601
77636973	77636996	5	+	28162770	SKM1	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	0.13069258719963772	[30]	[59]	1	hSpCas9	negative selection	10713602
77637167	77637190	5	-	28162770	SKM1	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	-0.16041791569793676	[54]	[86]	-1	hSpCas9	negative selection	10713603
77637084	77637107	5	-	28162770	SKM1	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	0.25600081397926744	[35]	[75]	2	hSpCas9	negative selection	10713604
77637055	77637078	5	+	28162770	SKM1	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-2.097636140635433	[45]	[18]	-8	hSpCas9	negative selection	10713605
77637192	77637215	5	-	28162770	PL21	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	0.49969989634822776	[38]	[23]	4	hSpCas9	negative selection	10882962
77637027	77637050	5	-	28162770	PL21	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	0.07950990930378128	[186]	[85]	0	hSpCas9	negative selection	10882963
77637180	77637203	5	+	28162770	PL21	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	0.1631454070071185	[157]	[76]	1	hSpCas9	negative selection	10882964
77637108	77637131	5	-	28162770	PL21	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.5005345478270411	[431]	[265]	4	hSpCas9	negative selection	10882965
77637069	77637092	5	-	28162770	PL21	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	0.282601774681293	[220]	[116]	2	hSpCas9	negative selection	10882966
77637013	77637036	5	-	28162770	PL21	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.7731294735444003	[362]	[269]	6	hSpCas9	negative selection	10882967
77636973	77636996	5	+	28162770	PL21	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	0.1762928725349524	[60]	[29]	1	hSpCas9	negative selection	10882968
77637167	77637190	5	-	28162770	PL21	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	0.021169473444000775	[119]	[52]	0	hSpCas9	negative selection	10882969
77637084	77637107	5	-	28162770	PL21	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	-0.18688350861992697	[135]	[51]	-1	hSpCas9	negative selection	10882970
77637055	77637078	5	+	28162770	PL21	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-2.2990930122059523	[146]	[12]	-8	hSpCas9	negative selection	10882971
77637192	77637215	5	-	28162770	P31FUJ	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	-0.5953722837990867	[53]	[41]	-5	hSpCas9	negative selection	11052328
77637027	77637050	5	-	28162770	P31FUJ	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	-0.7206660170304535	[236]	[168]	-5	hSpCas9	negative selection	11052329
77637180	77637203	5	+	28162770	P31FUJ	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	-0.24121444423057886	[171]	[170]	-2	hSpCas9	negative selection	11052330
77637108	77637131	5	-	28162770	P31FUJ	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.6832294940162031	[450]	[850]	7	hSpCas9	negative selection	11052331
77637069	77637092	5	-	28162770	P31FUJ	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	-0.35589733538632523	[268]	[246]	-3	hSpCas9	negative selection	11052332
77637013	77637036	5	-	28162770	P31FUJ	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.47589566472902234	[267]	[437]	5	hSpCas9	negative selection	11052333
77636973	77636996	5	+	28162770	P31FUJ	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	0.24719073670523528	[113]	[158]	2	hSpCas9	negative selection	11052334
77637167	77637190	5	-	28162770	P31FUJ	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	-0.6333401339981074	[197]	[149]	-5	hSpCas9	negative selection	11052335
77637084	77637107	5	-	28162770	P31FUJ	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	-0.1638548506968872	[142]	[149]	-1	hSpCas9	negative selection	11052336
77637055	77637078	5	+	28162770	P31FUJ	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-2.2384267536082567	[256]	[63]	-8	hSpCas9	negative selection	11052337
77637192	77637215	5	-	28162770	OCIAML5	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	0.8078579875383816	[24]	[78]	7	hSpCas9	negative selection	11221694
77637027	77637050	5	-	28162770	OCIAML5	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	0.28775639878889625	[112]	[248]	2	hSpCas9	negative selection	11221695
77637180	77637203	5	+	28162770	OCIAML5	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	-0.06680541965700965	[93]	[161]	0	hSpCas9	negative selection	11221696
77637108	77637131	5	-	28162770	OCIAML5	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.51928107806764	[263]	[682]	4	hSpCas9	negative selection	11221697
77637069	77637092	5	-	28162770	OCIAML5	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	0.5116816997179923	[67]	[174]	4	hSpCas9	negative selection	11221698
77637013	77637036	5	-	28162770	OCIAML5	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.8045083990179982	[130]	[412]	7	hSpCas9	negative selection	11221699
77636973	77636996	5	+	28162770	OCIAML5	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	1.8616292439793622	[24]	[163]	9	hSpCas9	negative selection	11221700
77637167	77637190	5	-	28162770	OCIAML5	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	0.8101610561838624	[102]	[325]	7	hSpCas9	negative selection	11221701
77637084	77637107	5	-	28162770	OCIAML5	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	1.176665147679319	[86]	[354]	8	hSpCas9	negative selection	11221702
77637055	77637078	5	+	28162770	OCIAML5	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-2.0537004320336476	[114]	[49]	-8	hSpCas9	negative selection	11221703
77637192	77637215	5	-	28162770	EOL1	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	-1.5990141844864785	[68]	[11]	-7	hSpCas9	negative selection	11391060
77637027	77637050	5	-	28162770	EOL1	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	-2.041663914973182	[210]	[26]	-8	hSpCas9	negative selection	11391061
77637180	77637203	5	+	28162770	EOL1	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	0.8995437654406402	[290]	[285]	7	hSpCas9	negative selection	11391062
77637108	77637131	5	-	28162770	EOL1	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.7081814252380256	[875]	[753]	6	hSpCas9	negative selection	11391063
77637069	77637092	5	-	28162770	EOL1	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	-0.12508299615406615	[413]	[199]	-1	hSpCas9	negative selection	11391064
77637013	77637036	5	-	28162770	EOL1	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.4818378538071362	[578]	[425]	4	hSpCas9	negative selection	11391065
77636973	77636996	5	+	28162770	EOL1	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	-0.4624753515387128	[135]	[51]	-3	hSpCas9	negative selection	11391066
77637167	77637190	5	-	28162770	EOL1	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	0.6111816901865963	[209]	[168]	5	hSpCas9	negative selection	11391067
77637084	77637107	5	-	28162770	EOL1	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	0.9794097066050529	[128]	[133]	8	hSpCas9	negative selection	11391068
77637055	77637078	5	+	28162770	EOL1	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-3.055999865763293	[220]	[13]	-9	hSpCas9	negative selection	11391069
77637192	77637215	5	-	28162770	MOLM13	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	0.9793897203247137	[46]	[66]	7	hSpCas9	negative selection	11560426
77637027	77637050	5	-	28162770	MOLM13	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	1.168329099685671	[231]	[376]	8	hSpCas9	negative selection	11560427
77637180	77637203	5	+	28162770	MOLM13	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	1.6080136054536494	[249]	[550]	9	hSpCas9	negative selection	11560428
77637108	77637131	5	-	28162770	MOLM13	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.7814653959981603	[588]	[731]	6	hSpCas9	negative selection	11560429
77637069	77637092	5	-	28162770	MOLM13	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	1.2272923648305405	[318]	[539]	8	hSpCas9	negative selection	11560430
77637013	77637036	5	-	28162770	MOLM13	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.6325200833173781	[363]	[407]	5	hSpCas9	negative selection	11560431
77636973	77636996	5	+	28162770	MOLM13	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	-1.207270928148156	[98]	[30]	-6	hSpCas9	negative selection	11560432
77637167	77637190	5	-	28162770	MOLM13	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	1.6177375902859548	[200]	[445]	9	hSpCas9	negative selection	11560433
77637084	77637107	5	-	28162770	MOLM13	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	0.8657663296652397	[147]	[194]	6	hSpCas9	negative selection	11560434
77637055	77637078	5	+	28162770	MOLM13	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-1.2991334464778073	[193]	[56]	-6	hSpCas9	negative selection	11560435
77637192	77637215	5	-	28162770	HEL	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	0.057776331279200566	[35]	[23]	0	hSpCas9	negative selection	11729792
77637027	77637050	5	-	28162770	HEL	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	-1.842687995169885	[195]	[34]	-7	hSpCas9	negative selection	11729793
77637180	77637203	5	+	28162770	HEL	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	0.38093172955056537	[234]	[195]	3	hSpCas9	negative selection	11729794
77637108	77637131	5	-	28162770	HEL	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	-0.14266711722360226	[635]	[368]	-1	hSpCas9	negative selection	11729795
77637069	77637092	5	-	28162770	HEL	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	0.6471984801910566	[322]	[323]	5	hSpCas9	negative selection	11729796
77637013	77637036	5	-	28162770	HEL	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.780855095211993	[427]	[470]	6	hSpCas9	negative selection	11729797
77636973	77636996	5	+	28162770	HEL	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	0.5408592179811434	[87]	[81]	4	hSpCas9	negative selection	11729798
77637167	77637190	5	-	28162770	HEL	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	0.8584675230557942	[154]	[179]	7	hSpCas9	negative selection	11729799
77637084	77637107	5	-	28162770	HEL	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	-0.017774701727976017	[146]	[92]	0	hSpCas9	negative selection	11729800
77637055	77637078	5	+	28162770	HEL	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-3.9571740101867707	[193]	[7]	-9	hSpCas9	negative selection	11729801
77637192	77637215	5	-	28162770	MV411	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	-1.2719366083108046	[42]	[14]	-7	hSpCas9	negative selection	11899158
77637027	77637050	5	-	28162770	MV411	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	-0.19586380071478998	[188]	[138]	-1	hSpCas9	negative selection	11899159
77637180	77637203	5	+	28162770	MV411	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	-1.3650056863604878	[158]	[51]	-7	hSpCas9	negative selection	11899160
77637108	77637131	5	-	28162770	MV411	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.5791466664627232	[440]	[554]	5	hSpCas9	negative selection	11899161
77637069	77637092	5	-	28162770	MV411	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	0.42459412145616354	[198]	[224]	4	hSpCas9	negative selection	11899162
77637013	77637036	5	-	28162770	MV411	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.49007076455684784	[272]	[322]	4	hSpCas9	negative selection	11899163
77636973	77636996	5	+	28162770	MV411	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	0.20436882889088936	[67]	[65]	1	hSpCas9	negative selection	11899164
77637167	77637190	5	-	28162770	MV411	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	0.3830926501403415	[141]	[155]	3	hSpCas9	negative selection	11899165
77637084	77637107	5	-	28162770	MV411	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	1.4862244103698918	[99]	[235]	9	hSpCas9	negative selection	11899166
77637055	77637078	5	+	28162770	MV411	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-1.4010900787158471	[115]	[36]	-7	hSpCas9	negative selection	11899167
77637192	77637215	5	-	28162770	MONOMAC1	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	1.8304438893625532	[12]	[52]	9	hSpCas9	negative selection	12068524
77637027	77637050	5	-	28162770	MONOMAC1	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	0.5234406243180836	[87]	[144]	5	hSpCas9	negative selection	12068525
77637180	77637203	5	+	28162770	MONOMAC1	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	0.23834929761109255	[87]	[118]	2	hSpCas9	negative selection	12068526
77637108	77637131	5	-	28162770	MONOMAC1	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	-0.2539639151443893	[335]	[322]	-2	hSpCas9	negative selection	12068527
77637069	77637092	5	-	28162770	MONOMAC1	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	-0.24661887591011414	[147]	[142]	-2	hSpCas9	negative selection	12068528
77637013	77637036	5	-	28162770	MONOMAC1	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	-0.07934180438979921	[199]	[216]	0	hSpCas9	negative selection	12068529
77636973	77636996	5	+	28162770	MONOMAC1	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	-0.5725459821517602	[47]	[36]	-5	hSpCas9	negative selection	12068530
77637167	77637190	5	-	28162770	MONOMAC1	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	-0.08247708279669792	[120]	[130]	0	hSpCas9	negative selection	12068531
77637084	77637107	5	-	28162770	MONOMAC1	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	0.6919318405517025	[53]	[99]	6	hSpCas9	negative selection	12068532
77637055	77637078	5	+	28162770	MONOMAC1	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-2.5525175016579427	[86]	[16]	-9	hSpCas9	negative selection	12068533
77637192	77637215	5	-	28162770	OCIAML2	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	1.7772976882014242	[3]	[75]	9	hSpCas9	negative selection	12237890
77637027	77637050	5	-	28162770	OCIAML2	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	-0.944084010746327	[41]	[120]	-6	hSpCas9	negative selection	12237891
77637180	77637203	5	+	28162770	OCIAML2	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	0.5091922928202085	[26]	[212]	5	hSpCas9	negative selection	12237892
77637108	77637131	5	-	28162770	OCIAML2	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.6280364930303293	[82]	[710]	6	hSpCas9	negative selection	12237893
77637069	77637092	5	-	28162770	OCIAML2	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	0.7109769812477864	[40]	[371]	7	hSpCas9	negative selection	12237894
77637013	77637036	5	-	28162770	OCIAML2	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.14926646558838197	[67]	[417]	1	hSpCas9	negative selection	12237895
77636973	77636996	5	+	28162770	OCIAML2	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	-1.1751739417159899	[21]	[53]	-6	hSpCas9	negative selection	12237896
77637167	77637190	5	-	28162770	OCIAML2	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	0.6168330160081781	[13]	[118]	6	hSpCas9	negative selection	12237897
77637084	77637107	5	-	28162770	OCIAML2	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	-0.590924058959873	[24]	[91]	-4	hSpCas9	negative selection	12237898
77637055	77637078	5	+	28162770	OCIAML2	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-2.272690447630252	[33]	[38]	-8	hSpCas9	negative selection	12237899
77637192	77637215	5	-	28162770	OCIAML3	viability	CGAGCTTCTGGGCCACCGGGAGG	OTP	ENSG00000171540	0.9667073141503155	[9]	[58]	8	hSpCas9	negative selection	12407256
77637027	77637050	5	-	28162770	OCIAML3	viability	GGCGGTGAGCGCCAAAGACCCGG	OTP	ENSG00000171540	0.7727746903474597	[37]	[195]	7	hSpCas9	negative selection	12407257
77637180	77637203	5	+	28162770	OCIAML3	viability	TACACTTCACCGCCTCCCGGTGG	OTP	ENSG00000171540	1.7775512222877996	[39]	[413]	9	hSpCas9	negative selection	12407258
77637108	77637131	5	-	28162770	OCIAML3	viability	GCCCAACTCTGACCCAGTGGAGG	OTP	ENSG00000171540	0.10557153795193419	[128]	[418]	1	hSpCas9	negative selection	12407259
77637069	77637092	5	-	28162770	OCIAML3	viability	CGGGGAGGACATCACCACAGTGG	OTP	ENSG00000171540	0.08406426478847445	[69]	[223]	0	hSpCas9	negative selection	12407260
77637013	77637036	5	-	28162770	OCIAML3	viability	AAGACCCGGACAAGCAGCCCGGG	OTP	ENSG00000171540	0.9790316930211737	[80]	[481]	8	hSpCas9	negative selection	12407261
77636973	77636996	5	+	28162770	OCIAML3	viability	GCTGCTGGCCGGCTTGGCTGGGG	OTP	ENSG00000171540	3.032431496373152	[9]	[246]	9	hSpCas9	negative selection	12407262
77637167	77637190	5	-	28162770	OCIAML3	viability	GTGAAGTGTAGGCTGGGCGTGGG	OTP	ENSG00000171540	0.0689573723982661	[41]	[132]	0	hSpCas9	negative selection	12407263
77637084	77637107	5	-	28162770	OCIAML3	viability	AGCCACTCTGCTGCCCGGGGAGG	OTP	ENSG00000171540	-0.6231539859836797	[24]	[48]	-5	hSpCas9	negative selection	12407264
77637055	77637078	5	+	28162770	OCIAML3	viability	GGCCGGAGTAGAGCCCACTGTGG	OTP	ENSG00000171540	-1.5544792761375255	[35]	[36]	-8	hSpCas9	negative selection	12407265