Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:6608
• Symbol:smo
• Description:smoothened, frizzled class receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/smo

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
129203448	129203471	7	+	26472758	Jiyoye	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	-0.09978460721400961	[80]	[56]	0	hSpCas9	negative selection	152332
129203400	129203423	7	-	26472758	Jiyoye	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	1.056268219646745	[43]	[68]	7	hSpCas9	negative selection	152333
129203422	129203445	7	-	26472758	Jiyoye	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	1.1330004180668793	[103]	[171]	7	hSpCas9	negative selection	152334
129205238	129205261	7	-	26472758	Jiyoye	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	0.8773544349771781	[230]	[319]	6	hSpCas9	negative selection	152335
129205261	129205284	7	+	26472758	Jiyoye	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	-4.3477121206575955	[26]	[0]	-9	hSpCas9	negative selection	152336
129205277	129205300	7	+	26472758	Jiyoye	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	0.3794303910229694	[104]	[102]	3	hSpCas9	negative selection	152337
129206309	129206332	7	-	26472758	Jiyoye	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	0.022511531270548613	[46]	[35]	0	hSpCas9	negative selection	152338
129203448	129203471	7	+	26472758	KBM7	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	0.79177409730676	[208,67]	[108,105]	8	hSpCas9	negative selection	343450
129203400	129203423	7	-	26472758	KBM7	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	0.5959070073605972	[162,257]	[91,208]	6	hSpCas9	negative selection	343451
129203422	129203445	7	-	26472758	KBM7	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	0.5613947345911874	[1054,757]	[630,612]	6	hSpCas9	negative selection	343452
129205238	129205261	7	-	26472758	KBM7	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-0.23131197549218951	[1284,1068]	[576,372]	-2	hSpCas9	negative selection	343453
129205261	129205284	7	+	26472758	KBM7	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	0.12158385897552781	[50,10]	[16,12]	1	hSpCas9	negative selection	343454
129205277	129205300	7	+	26472758	KBM7	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-1.081042548693913	[718,774]	[186,149]	-7	hSpCas9	negative selection	343455
129206309	129206332	7	-	26472758	KBM7	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	0.2077993215279732	[227,301]	[171,123]	2	hSpCas9	negative selection	343456
129203448	129203471	7	+	26472758	Raji	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	-0.9149842776548549	[64]	[7]	-6	hSpCas9	negative selection	534568
129203400	129203423	7	-	26472758	Raji	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	0.5801365325087305	[97]	[33]	5	hSpCas9	negative selection	534569
129203422	129203445	7	-	26472758	Raji	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	0.48445318445342295	[307]	[99]	4	hSpCas9	negative selection	534570
129205238	129205261	7	-	26472758	Raji	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	0.2041969085284998	[388]	[103]	2	hSpCas9	negative selection	534571
129205261	129205284	7	+	26472758	Raji	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	0.8849911140371516	[34]	[14]	7	hSpCas9	negative selection	534572
129205277	129205300	7	+	26472758	Raji	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-0.5555814773488299	[189]	[29]	-4	hSpCas9	negative selection	534573
129206309	129206332	7	-	26472758	Raji	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	-0.39957645334628356	[107]	[18]	-3	hSpCas9	negative selection	534574
129203448	129203471	7	+	26472758	K562	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	-0.5868268145991786	[136]	[76]	-4	hSpCas9	negative selection	725686
129203400	129203423	7	-	26472758	K562	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	1.107970448416239	[204]	[372]	8	hSpCas9	negative selection	725687
129203422	129203445	7	-	26472758	K562	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	-0.7121744848183538	[752]	[387]	-4	hSpCas9	negative selection	725688
129205238	129205261	7	-	26472758	K562	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-0.5159857794645876	[785]	[463]	-3	hSpCas9	negative selection	725689
129205261	129205284	7	+	26472758	K562	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	2.0099534740294236	[19]	[67]	9	hSpCas9	negative selection	725690
129205277	129205300	7	+	26472758	K562	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-0.9806829809279871	[532]	[227]	-5	hSpCas9	negative selection	725691
129206309	129206332	7	-	26472758	K562	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	-0.2393970495978095	[178]	[127]	-2	hSpCas9	negative selection	725692
129189356	129189379	7	-	26627737	DLD1	viability	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	0.13242369587791636	[368]	[165,93,118]	1	hSpCas9	negative selection	834884
129203514	129203537	7	+	26627737	DLD1	viability	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-0.1988505361489577	[471]	[213,139,44]	-2	hSpCas9	negative selection	834885
129205328	129205351	7	+	26627737	DLD1	viability	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	-0.007851123743807142	[729]	[281,219,184]	0	hSpCas9	negative selection	834886
129205728	129205751	7	-	26627737	DLD1	viability	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	-0.28849862830602874	[396]	[44,163,98]	-3	hSpCas9	negative selection	834887
129206167	129206190	7	-	26627737	DLD1	viability	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	1.3007232124387613	[127]	[94,166,44]	9	hSpCas9	negative selection	834888
129206550	129206573	7	-	26627737	DLD1	viability	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	0.7985522990621874	[175]	[105,63,112]	7	hSpCas9	negative selection	834889
129189356	129189379	7	-	26627737	GBM cells	viability after 5 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	1.586126433854792	[58]	[70,118]	9	hSpCas9	negative selection	917199
129203514	129203537	7	+	26627737	GBM cells	viability after 5 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-0.19730144037361774	[185]	[105,67]	-3	hSpCas9	negative selection	917200
129205328	129205351	7	+	26627737	GBM cells	viability after 5 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.4027396128814362	[255]	[161,200]	6	hSpCas9	negative selection	917201
129205728	129205751	7	-	26627737	GBM cells	viability after 5 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	0.11540569478244911	[104]	[47,73]	1	hSpCas9	negative selection	917202
129206167	129206190	7	-	26627737	GBM cells	viability after 5 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-0.307537002581741	[59]	[30,20]	-5	hSpCas9	negative selection	917203
129206550	129206573	7	-	26627737	GBM cells	viability after 5 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	-0.08222709786299853	[151]	[85,67]	-1	hSpCas9	negative selection	917204
129189356	129189379	7	-	26627737	GBM cells	viability after 13 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	0.9936471006662722	[58]	[28,91]	9	hSpCas9	negative selection	999514
129203514	129203537	7	+	26627737	GBM cells	viability after 13 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-0.04429557798066924	[185]	[109,87]	0	hSpCas9	negative selection	999515
129205328	129205351	7	+	26627737	GBM cells	viability after 13 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.4378200502536568	[255]	[282,110]	5	hSpCas9	negative selection	999516
129205728	129205751	7	-	26627737	GBM cells	viability after 13 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	-0.24408919125523632	[104]	[46,48]	-3	hSpCas9	negative selection	999517
129206167	129206190	7	-	26627737	GBM cells	viability after 13 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-0.24767723150676924	[59]	[38,17]	-3	hSpCas9	negative selection	999518
129206550	129206573	7	-	26627737	GBM cells	viability after 13 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	-0.3974964165495729	[151]	[39,80]	-5	hSpCas9	negative selection	999519
129189356	129189379	7	-	26627737	GBM cells	viability after 21 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	1.81108643652309	[58]	[112,111]	9	hSpCas9	negative selection	1081829
129203514	129203537	7	+	26627737	GBM cells	viability after 21 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	0.22643192256650432	[185]	[112,122]	2	hSpCas9	negative selection	1081830
129205328	129205351	7	+	26627737	GBM cells	viability after 21 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.32961125358903287	[255]	[179,169]	3	hSpCas9	negative selection	1081831
129205728	129205751	7	-	26627737	GBM cells	viability after 21 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	-0.653882042288275	[104]	[41,30]	-5	hSpCas9	negative selection	1081832
129206167	129206190	7	-	26627737	GBM cells	viability after 21 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-1.400867290933443	[59]	[15,8]	-8	hSpCas9	negative selection	1081833
129206550	129206573	7	-	26627737	GBM cells	viability after 21 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	-0.7760679828257602	[151]	[42,52]	-6	hSpCas9	negative selection	1081834
129189356	129189379	7	-	26627737	RPE1	viability after 9 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	0.34129177579419834	[604]	[156,346]	2	hSpCas9	negative selection	1164144
129203514	129203537	7	+	26627737	RPE1	viability after 9 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-0.4059417965258352	[710]	[229,87]	-3	hSpCas9	negative selection	1164145
129205328	129205351	7	+	26627737	RPE1	viability after 9 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	-0.7669949685438959	[1418]	[226,304]	-5	hSpCas9	negative selection	1164146
129205728	129205751	7	-	26627737	RPE1	viability after 9 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	3.2566789442360613	[79]	[272,195]	9	hSpCas9	negative selection	1164147
129206167	129206190	7	-	26627737	RPE1	viability after 9 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-0.6398295392056403	[127]	[9,45]	-4	hSpCas9	negative selection	1164148
129206550	129206573	7	-	26627737	RPE1	viability after 9 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	0.41083001920596685	[549]	[279,162]	3	hSpCas9	negative selection	1164149
129189356	129189379	7	-	26627737	RPE1	viability after 12 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	-0.0720168134572482	[604]	[158,149]	0	hSpCas9	negative selection	1246459
129203514	129203537	7	+	26627737	RPE1	viability after 12 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-0.14750026436456068	[710]	[187,155]	-1	hSpCas9	negative selection	1246460
129205328	129205351	7	+	26627737	RPE1	viability after 12 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	-0.6633695083757968	[1418]	[281,196]	-4	hSpCas9	negative selection	1246461
129205728	129205751	7	-	26627737	RPE1	viability after 12 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	3.5657861426285984	[79]	[322,181]	9	hSpCas9	negative selection	1246462
129206167	129206190	7	-	26627737	RPE1	viability after 12 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	0.2716473823610128	[127]	[41,40]	1	hSpCas9	negative selection	1246463
129206550	129206573	7	-	26627737	RPE1	viability after 12 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	0.38014572765151455	[549]	[151,234]	2	hSpCas9	negative selection	1246464
129189356	129189379	7	-	26627737	RPE1	viability after 15 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	-0.4869680290812166	[604]	[171,73]	-3	hSpCas9	negative selection	1328774
129203514	129203537	7	+	26627737	RPE1	viability after 15 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-0.7960032453642276	[710]	[124,106]	-5	hSpCas9	negative selection	1328775
129205328	129205351	7	+	26627737	RPE1	viability after 15 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	-0.7577998722109383	[1418]	[327,149]	-5	hSpCas9	negative selection	1328776
129205728	129205751	7	-	26627737	RPE1	viability after 15 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	3.2501526292945875	[79]	[337,96]	9	hSpCas9	negative selection	1328777
129206167	129206190	7	-	26627737	RPE1	viability after 15 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	0.1469372979228436	[127]	[34,44]	1	hSpCas9	negative selection	1328778
129206550	129206573	7	-	26627737	RPE1	viability after 15 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	0.39333234479185086	[549]	[212,195]	2	hSpCas9	negative selection	1328779
129189356	129189379	7	-	26627737	RPE1	viability after 18 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	-0.20084639067689702	[604]	[128,155]	-1	hSpCas9	negative selection	1411089
129203514	129203537	7	+	26627737	RPE1	viability after 18 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-1.5193777210159436	[710]	[64,68]	-7	hSpCas9	negative selection	1411090
129205328	129205351	7	+	26627737	RPE1	viability after 18 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	-0.6333709860289294	[1418]	[417,63]	-4	hSpCas9	negative selection	1411091
129205728	129205751	7	-	26627737	RPE1	viability after 18 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	4.554202326262543	[79]	[804,188]	9	hSpCas9	negative selection	1411092
129206167	129206190	7	-	26627737	RPE1	viability after 18 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-1.4547628667487746	[127]	[0,24]	-7	hSpCas9	negative selection	1411093
129206550	129206573	7	-	26627737	RPE1	viability after 18 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	0.2756862618957973	[549]	[184,173]	1	hSpCas9	negative selection	1411094
129189356	129189379	7	-	26627737	HeLa	viability after 8 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	0.8283614887251195	[266]	[295,200,145]	6	hSpCas9	negative selection	1493404
129203514	129203537	7	+	26627737	HeLa	viability after 8 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-1.1701625465384855	[323]	[100,26,67]	-8	hSpCas9	negative selection	1493405
129205328	129205351	7	+	26627737	HeLa	viability after 8 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.6982440871156368	[287]	[325,166,147]	6	hSpCas9	negative selection	1493406
129205728	129205751	7	-	26627737	HeLa	viability after 8 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	-0.48947118014547364	[70]	[31,10,24]	-5	hSpCas9	negative selection	1493407
129206167	129206190	7	-	26627737	HeLa	viability after 8 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-0.5561662723498246	[89]	[58,0,26]	-5	hSpCas9	negative selection	1493408
129206550	129206573	7	-	26627737	HeLa	viability after 8 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	2.218083329536263	[71]	[148,142,145]	9	hSpCas9	negative selection	1493409
129189356	129189379	7	-	26627737	HeLa	viability after 12 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	0.22113870519061934	[266]	[211,102,75]	2	hSpCas9	negative selection	1575719
129203514	129203537	7	+	26627737	HeLa	viability after 12 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-0.885946490922441	[323]	[104,65,47]	-7	hSpCas9	negative selection	1575720
129205328	129205351	7	+	26627737	HeLa	viability after 12 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	1.0806116479298415	[287]	[338,229,190]	7	hSpCas9	negative selection	1575721
129205728	129205751	7	-	26627737	HeLa	viability after 12 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	1.4936308794001059	[70]	[56,64,126]	8	hSpCas9	negative selection	1575722
129206167	129206190	7	-	26627737	HeLa	viability after 12 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	0.7302492305023962	[89]	[111,0,79]	6	hSpCas9	negative selection	1575723
129206550	129206573	7	-	26627737	HeLa	viability after 12 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	0.14336720236470324	[71]	[12,32,51]	1	hSpCas9	negative selection	1575724
129189356	129189379	7	-	26627737	HeLa	viability after 15 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	-0.0701251593127935	[266]	[114,157,31]	0	hSpCas9	negative selection	1658034
129203514	129203537	7	+	26627737	HeLa	viability after 15 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	0.3059184920393107	[323]	[315,82,81]	2	hSpCas9	negative selection	1658035
129205328	129205351	7	+	26627737	HeLa	viability after 15 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.7614213891135012	[287]	[205,144,248]	6	hSpCas9	negative selection	1658036
129205728	129205751	7	-	26627737	HeLa	viability after 15 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	1.1013446418684738	[70]	[3,69,116]	7	hSpCas9	negative selection	1658037
129206167	129206190	7	-	26627737	HeLa	viability after 15 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-1.4667857659627108	[89]	[10,0,28]	-8	hSpCas9	negative selection	1658038
129206550	129206573	7	-	26627737	HeLa	viability after 15 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	2.2933819515876666	[71]	[211,136,75]	9	hSpCas9	negative selection	1658039
129189356	129189379	7	-	26627737	HeLa	viability after 18 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	-0.06886289408198376	[266]	[77,129,31]	0	hSpCas9	negative selection	1740349
129203514	129203537	7	+	26627737	HeLa	viability after 18 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	0.2699644026521116	[323]	[203,68,81]	2	hSpCas9	negative selection	1740350
129205328	129205351	7	+	26627737	HeLa	viability after 18 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.7431311375768657	[287]	[134,117,248]	6	hSpCas9	negative selection	1740351
129205728	129205751	7	-	26627737	HeLa	viability after 18 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	1.1126227133766045	[70]	[1,59,116]	7	hSpCas9	negative selection	1740352
129206167	129206190	7	-	26627737	HeLa	viability after 18 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-1.538070989353483	[89]	[5,0,28]	-8	hSpCas9	negative selection	1740353
129206550	129206573	7	-	26627737	HeLa	viability after 18 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	2.341121617516451	[71]	[147,117,75]	9	hSpCas9	negative selection	1740354
129189356	129189379	7	-	26627737	HCT116	viability after 6 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	0.26368928988020646	[304]	[141,10]	1	hSpCas9	negative selection	1822664
129203514	129203537	7	+	26627737	HCT116	viability after 6 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	0.15469260284382863	[707]	[188,87]	0	hSpCas9	negative selection	1822665
129205328	129205351	7	+	26627737	HCT116	viability after 6 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	-1.2651789222541645	[656]	[80,21]	-6	hSpCas9	negative selection	1822666
129205728	129205751	7	-	26627737	HCT116	viability after 6 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	0.14416496202275542	[666]	[189,74]	0	hSpCas9	negative selection	1822667
129206167	129206190	7	-	26627737	HCT116	viability after 6 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	0.7371018047643367	[175]	[0,70]	4	hSpCas9	negative selection	1822668
129206550	129206573	7	-	26627737	HCT116	viability after 6 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	-2.564474300107884	[371]	[25,0]	-8	hSpCas9	negative selection	1822669
129189356	129189379	7	-	26627737	HCT116	viability after 8 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	0.24427387278894053	[305]	[240,166,191]	2	hSpCas9	negative selection	1904979
129203514	129203537	7	+	26627737	HCT116	viability after 8 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-0.8072372888200134	[451]	[129,89,205]	-7	hSpCas9	negative selection	1904980
129205328	129205351	7	+	26627737	HCT116	viability after 8 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.785007491921659	[330]	[354,310,277]	7	hSpCas9	negative selection	1904981
129205728	129205751	7	-	26627737	HCT116	viability after 8 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	0.15625881559889865	[95]	[97,57,21]	1	hSpCas9	negative selection	1904982
129206167	129206190	7	-	26627737	HCT116	viability after 8 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-0.6445173325292224	[148]	[25,70,59]	-7	hSpCas9	negative selection	1904983
129206550	129206573	7	-	26627737	HCT116	viability after 8 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	1.1602698883811238	[89]	[101,89,139]	8	hSpCas9	negative selection	1904984
129189356	129189379	7	-	26627737	HCT116	viability after 9 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	0.6849534366683381	[304]	[164,103]	5	hSpCas9	negative selection	1987294
129203514	129203537	7	+	26627737	HCT116	viability after 9 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-0.19314611109272495	[707]	[304,54]	-1	hSpCas9	negative selection	1987295
129205328	129205351	7	+	26627737	HCT116	viability after 9 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.550864800225017	[656]	[442,109]	4	hSpCas9	negative selection	1987296
129205728	129205751	7	-	26627737	HCT116	viability after 9 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	0.28308017278836195	[666]	[352,108]	2	hSpCas9	negative selection	1987297
129206167	129206190	7	-	26627737	HCT116	viability after 9 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-2.0867628282637556	[175]	[19,3]	-8	hSpCas9	negative selection	1987298
129206550	129206573	7	-	26627737	HCT116	viability after 9 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	-0.02717198739049098	[371]	[49,134]	0	hSpCas9	negative selection	1987299
129189356	129189379	7	-	26627737	HCT116	viability after 12 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	0.1237291563679771	[305]	[129,273,127]	1	hSpCas9	negative selection	2069609
129203514	129203537	7	+	26627737	HCT116	viability after 12 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-0.6341355626522431	[451]	[108,151,201]	-6	hSpCas9	negative selection	2069610
129205328	129205351	7	+	26627737	HCT116	viability after 12 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.36966985927019963	[330]	[106,199,376]	3	hSpCas9	negative selection	2069611
129205728	129205751	7	-	26627737	HCT116	viability after 12 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	0.49946141355912976	[95]	[91,23,94]	5	hSpCas9	negative selection	2069612
129206167	129206190	7	-	26627737	HCT116	viability after 12 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-1.0055631331026849	[148]	[35,27,52]	-8	hSpCas9	negative selection	2069613
129206550	129206573	7	-	26627737	HCT116	viability after 12 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	0.77304152336231	[89]	[75,84,81]	7	hSpCas9	negative selection	2069614
129189356	129189379	7	-	26627737	HCT116	viability after 15 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	-0.02181936964366215	[305]	[259,190,79]	0	hSpCas9	negative selection	2151924
129203514	129203537	7	+	26627737	HCT116	viability after 15 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-0.4696599564927353	[451]	[152,203,200]	-5	hSpCas9	negative selection	2151925
129205328	129205351	7	+	26627737	HCT116	viability after 15 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.858953243176453	[330]	[261,313,446]	7	hSpCas9	negative selection	2151926
129205728	129205751	7	-	26627737	HCT116	viability after 15 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	0.4400719759398901	[95]	[15,23,175]	4	hSpCas9	negative selection	2151927
129206167	129206190	7	-	26627737	HCT116	viability after 15 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-0.555499335353218	[148]	[57,4,110]	-5	hSpCas9	negative selection	2151928
129206550	129206573	7	-	26627737	HCT116	viability after 15 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	0.14156637063178246	[89]	[88,33,51]	1	hSpCas9	negative selection	2151929
129189356	129189379	7	-	26627737	HCT116	viability after 18 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	0.3712061153189218	[305]	[250,209,107]	3	hSpCas9	negative selection	2234239
129203514	129203537	7	+	26627737	HCT116	viability after 18 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	-0.19167112268271685	[451]	[39,321,203]	-2	hSpCas9	negative selection	2234240
129205328	129205351	7	+	26627737	HCT116	viability after 18 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	1.0714518902395374	[330]	[251,309,453]	8	hSpCas9	negative selection	2234241
129205728	129205751	7	-	26627737	HCT116	viability after 18 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	-0.6453562552746226	[95]	[29,3,57]	-5	hSpCas9	negative selection	2234242
129206167	129206190	7	-	26627737	HCT116	viability after 18 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	0.4876637094173262	[148]	[123,65,115]	4	hSpCas9	negative selection	2234243
129206550	129206573	7	-	26627737	HCT116	viability after 18 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	0.6044098227193619	[89]	[114,49,32]	5	hSpCas9	negative selection	2234244
129189155	129189179	7	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GCCGCTGCCCGCCCAGCGCGGGGG	SMO	ENSG00000128602	1.432783319146092	[1360,358,1109]	[0,0,0]	4	hSpCas9	positive selection	2381459
129189155	129189179	7	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GCCGCTGCCCGCCCAGCGCGGGGG	SMO	ENSG00000128602	1.432783319146092	[1360,358,1109]	[0,0,0]	4	hSpCas9	positive selection	2381460
129189230	129189253	7	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GGCCGGGGGGCGGCCTCGAGCGG	SMO	ENSG00000128602	2.5258703483145606	[600,334,387]	[0,0,0]	6	hSpCas9	positive selection	2381461
129189230	129189253	7	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GGCCGGGGGGCGGCCTCGAGCGG	SMO	ENSG00000128602	2.5258703483145606	[600,334,387]	[0,0,0]	6	hSpCas9	positive selection	2381462
129205267	129205291	7	+	24717434	HeLa	essential genes for diphteria toxin toxicity	ACAACCCCAAGAGCTGGTACGAGG	SMO	ENSG00000128602	9.365765918637353	[5369,4079,4260]	[7,3565,1]	8	hSpCas9	positive selection	2381463
129205267	129205291	7	+	24717434	HeLa	essential genes for diphteria toxin toxicity	ACAACCCCAAGAGCTGGTACGAGG	SMO	ENSG00000128602	9.365765918637353	[5369,4079,4260]	[7,3565,1]	8	hSpCas9	positive selection	2381464
129189155	129189179	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCCGCTGCCCGCCCAGCGCGGGGG	SMO	ENSG00000128602	3.7563880215137795	[1360,358,1109]	[0,12,0]	6	hSpCas9	positive selection	2382872
129189155	129189179	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCCGCTGCCCGCCCAGCGCGGGGG	SMO	ENSG00000128602	3.7563880215137795	[1360,358,1109]	[0,12,0]	6	hSpCas9	positive selection	2382873
129189155	129189179	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCCGCTGCCCGCCCAGCGCGGGGG	SMO	ENSG00000128602	3.7563880215137795	[1360,358,1109]	[0,12,0]	6	hSpCas9	positive selection	2382874
129189230	129189253	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GGCCGGGGGGCGGCCTCGAGCGG	SMO	ENSG00000128602	2.5259114852718634	[600,334,387]	[0,0,0]	5	hSpCas9	positive selection	2382875
129189230	129189253	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GGCCGGGGGGCGGCCTCGAGCGG	SMO	ENSG00000128602	2.5259114852718634	[600,334,387]	[0,0,0]	5	hSpCas9	positive selection	2382876
129189230	129189253	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GGCCGGGGGGCGGCCTCGAGCGG	SMO	ENSG00000128602	2.5259114852718634	[600,334,387]	[0,0,0]	5	hSpCas9	positive selection	2382877
129205267	129205291	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ACAACCCCAAGAGCTGGTACGAGG	SMO	ENSG00000128602	10.667583737730057	[5369,4079,4260]	[0,8813,1]	9	hSpCas9	positive selection	2382878
129205267	129205291	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ACAACCCCAAGAGCTGGTACGAGG	SMO	ENSG00000128602	10.667583737730057	[5369,4079,4260]	[0,8813,1]	9	hSpCas9	positive selection	2382879
129205267	129205291	7	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ACAACCCCAAGAGCTGGTACGAGG	SMO	ENSG00000128602	10.667583737730057	[5369,4079,4260]	[0,8813,1]	9	hSpCas9	positive selection	2382880
129205648	129205671	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTAGAAGAGAATAACAGCAGGG	SMO	ENSG00000128602	-0.45401698641552835	[3,3]	[3,0]	-6	hSpCas9	positive selection	3022263
129205350	129205373	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACATGCACAGCTACATCGCGG	SMO	ENSG00000128602	-0.10268951886310199	[3,3]	[3,2]	-1	hSpCas9	positive selection	3022264
129205648	129205671	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTAGAAGAGAATAACAGCAGGG	SMO	ENSG00000128602	0.01035628442096681	[3,3]	[2,2]	0	hSpCas9	positive selection	3090121
129205350	129205373	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACATGCACAGCTACATCGCGG	SMO	ENSG00000128602	-0.5791683450361759	[3,3]	[1,0]	-7	hSpCas9	positive selection	3090122
129206505	129206528		+	24336571	A375	resistance to PLX after 7 days	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	0.15639071235418567	[28,21]	[29,26]	5	hSpCas9	positive selection	3146209
129205273	129205296		-	24336571	A375	resistance to PLX after 7 days	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.018123936054706746	[42,30]	[37,33]	0	hSpCas9	positive selection	3146210
129205346	129205369		-	24336571	A375	resistance to PLX after 7 days	CGATGTAGCTGTGCATGTCCTGG	SMO	ENSG00000128602	0.003386216230943151	[23,21]	[22,21]	0	hSpCas9	positive selection	3146211
129206532	129206555		+	24336571	A375	resistance to PLX after 7 days	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.2621565277492188	[5,6]	[4,4]	-7	hSpCas9	positive selection	3146212
129206505	129206528		+	24336571	A375	resistance to PLX after 14 days	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.5662083821480948	[19,19]	[5,5]	-6	hSpCas9	positive selection	3204002
129205273	129205296		-	24336571	A375	resistance to PLX after 14 days	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.904957200349979	[34,34]	[7,8]	-9	hSpCas9	positive selection	3204003
129205346	129205369		-	24336571	A375	resistance to PLX after 14 days	CGATGTAGCTGTGCATGTCCTGG	SMO	ENSG00000128602	-0.9226774226893972	[21,28]	[6,4]	-9	hSpCas9	positive selection	3204004
129206532	129206555		+	24336571	A375	resistance to PLX after 14 days	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.1941747079125189	[4,7]	[1,1]	-2	hSpCas9	positive selection	3204005
129206505	129206528		+	24336571	A375	viability after 7 days	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	0.13007439871655535	[23]	[28,21]	2	hSpCas9	negative selection	3261795
129205273	129205296		-	24336571	A375	viability after 7 days	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	1.0748157705111177	[17]	[42,30]	9	hSpCas9	negative selection	3261796
129205346	129205369		-	24336571	A375	viability after 7 days	CGATGTAGCTGTGCATGTCCTGG	SMO	ENSG00000128602	0.6765363685636169	[14]	[23,21]	8	hSpCas9	negative selection	3261797
129206532	129206555		+	24336571	A375	viability after 7 days	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.7985105177422134	[11]	[5,6]	-8	hSpCas9	negative selection	3261798
129206505	129206528		+	24336571	A375	viability after 14 days	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.16686722490085537	[23]	[19,19]	-2	hSpCas9	negative selection	3319588
129205273	129205296		-	24336571	A375	viability after 14 days	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	1.0214150679107215	[17]	[34,34]	9	hSpCas9	negative selection	3319589
129205346	129205369		-	24336571	A375	viability after 14 days	CGATGTAGCTGTGCATGTCCTGG	SMO	ENSG00000128602	0.8499448070117445	[14]	[21,28]	9	hSpCas9	negative selection	3319590
129206532	129206555		+	24336571	A375	viability after 14 days	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.7505807770885051	[11]	[4,7]	-7	hSpCas9	negative selection	3319591
129205273	129205296	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.009460329249066228	[153,153]	[0,0]	0	hSpCas9	positive selection	3393937
129189430	129189453	7	+	26780180	HT29	viability (Avana library 4 designs)	CGGAGACTCGGACTCCCAGGAGG	SMO	ENSG00000128602	2.65693983237974	[]	[]	8	hSpCas9	negative selection	3460847
129205648	129205671	7	-	26780180	HT29	viability (Avana library 4 designs)	CGTAGAAGAGAATAACAGCAGGG	SMO	ENSG00000128602	2.11437900364622	[]	[]	7	hSpCas9	negative selection	3460848
129205349	129205372	7	+	26780180	HT29	viability (Avana library 4 designs)	GGACATGCACAGCTACATCGCGG	SMO	ENSG00000128602	0.992055789729827	[]	[]	4	hSpCas9	negative selection	3460849
129205251	129205274	7	-	26780180	HT29	viability (Avana library 4 designs)	GGGTTGTCTGTCCGAACCAAGGG	SMO	ENSG00000128602	1.35732285048313	[]	[]	5	hSpCas9	negative selection	3460850
129189430	129189453	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGGAGACTCGGACTCCCAGGAGG	SMO	ENSG00000128602	2.14741919956339	[]	[]	3	hSpCas9	negative selection	3561420
129205251	129205274	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGTTGTCTGTCCGAACCAAGGG	SMO	ENSG00000128602	3.99253080293554	[]	[]	6	hSpCas9	negative selection	3561421
129205648	129205671	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGTAGAAGAGAATAACAGCAGGG	SMO	ENSG00000128602	-4.89613082684622	[]	[]	-5	hSpCas9	negative selection	3561422
129205349	129205372	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGACATGCACAGCTACATCGCGG	SMO	ENSG00000128602	-11.4373673716515	[]	[]	-8	hSpCas9	negative selection	3561423
129189430	129189453	7	+	26780180	A375	viability (Avana lentiGuide)	CGGAGACTCGGACTCCCAGGAGG	SMO	ENSG00000128602	4.59911891695456	[]	[]	4	hSpCas9	negative selection	3670079
129205251	129205274	7	-	26780180	A375	viability (Avana lentiGuide)	GGGTTGTCTGTCCGAACCAAGGG	SMO	ENSG00000128602	9.79485714300706	[]	[]	6	hSpCas9	negative selection	3670080
129205648	129205671	7	-	26780180	A375	viability (Avana lentiGuide)	CGTAGAAGAGAATAACAGCAGGG	SMO	ENSG00000128602	0.612677125434625	[]	[]	0	hSpCas9	negative selection	3670081
129205349	129205372	7	+	26780180	A375	viability (Avana lentiGuide)	GGACATGCACAGCTACATCGCGG	SMO	ENSG00000128602	3.08284388257163	[]	[]	3	hSpCas9	negative selection	3670082
129189430	129189453	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGAGACTCGGACTCCCAGGAGG	SMO	ENSG00000128602	-0.04463352987174929	[4]	[5,2]	0	hSpCas9	positive selection	3778686
129205251	129205274	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGTTGTCTGTCCGAACCAAGGG	SMO	ENSG00000128602	-0.0652873184303125	[5]	[5,3]	-1	hSpCas9	positive selection	3778687
129205648	129205671	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTAGAAGAGAATAACAGCAGGG	SMO	ENSG00000128602	-0.15470478315535874	[5]	[4,4]	-3	hSpCas9	positive selection	3778688
129205349	129205372	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACATGCACAGCTACATCGCGG	SMO	ENSG00000128602	-1.044866138288656	[4]	[2,1]	-9	hSpCas9	positive selection	3778689
129189430	129189453	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGAGACTCGGACTCCCAGGAGG	SMO	ENSG00000128602	-0.24674730414279814	[5]	[3,3]	-3	hSpCas9	positive selection	3887293
129205251	129205274	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGTTGTCTGTCCGAACCAAGGG	SMO	ENSG00000128602	-0.10028017866978782	[5]	[6,2]	-1	hSpCas9	positive selection	3887294
129205648	129205671	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTAGAAGAGAATAACAGCAGGG	SMO	ENSG00000128602	-0.24953349183873114	[4]	[1,4]	-3	hSpCas9	positive selection	3887295
129205349	129205372	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACATGCACAGCTACATCGCGG	SMO	ENSG00000128602	0.1875421615218965	[4]	[4,4]	4	hSpCas9	positive selection	3887296
129205240	129205263	7	+	26780180	A375	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	1.28908729016558	[]	[]	7	hSpCas9	negative selection	3997390
129206505	129206528	7	+	26780180	A375	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	0.534382689460268	[]	[]	1	hSpCas9	negative selection	3997391
129205273	129205296	7	-	26780180	A375	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.858455175839293	[]	[]	3	hSpCas9	negative selection	3997392
129206532	129206555	7	+	26780180	A375	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	1.52641625702495	[]	[]	8	hSpCas9	negative selection	3997393
129205240	129205263	7	+	26780180	HT29	viability (GeCKOv2 library)	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	1.03456189730876	[]	[]	5	hSpCas9	negative selection	4105356
129206505	129206528	7	+	26780180	HT29	viability (GeCKOv2 library)	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	0.816451095956391	[]	[]	3	hSpCas9	negative selection	4105357
129205273	129205296	7	-	26780180	HT29	viability (GeCKOv2 library)	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	1.23031005216212	[]	[]	6	hSpCas9	negative selection	4105358
129206532	129206555	7	+	26780180	HT29	viability (GeCKOv2 library)	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	1.97551640887978	[]	[]	9	hSpCas9	negative selection	4105359
129206505	129206528	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.09415150110516898	[4]	[2,2]	-2	hSpCas9	positive selection	4172296
129205273	129205296	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.05788453749711317	[4]	[2,2]	-1	hSpCas9	positive selection	4172297
129205346	129205369	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGATGTAGCTGTGCATGTCCTGG	SMO	ENSG00000128602	-0.2287558480013102	[4]	[1,2]	-5	hSpCas9	positive selection	4172298
129206532	129206555	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.6130269922701252	[3]	[0,0]	-9	hSpCas9	positive selection	4172299
129206505	129206528	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	0.3846261007545326	[4]	[5,2,1,0]	3	hSpCas9	positive selection	4236318
129205273	129205296	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.4651482467625552	[4]	[4,3,5,0]	3	hSpCas9	positive selection	4236319
129205346	129205369	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGATGTAGCTGTGCATGTCCTGG	SMO	ENSG00000128602	1.1974927804521198	[3]	[1,4,2,3]	8	hSpCas9	positive selection	4236320
129206532	129206555	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.2847443736122899	[2]	[0,0,0,0]	-4	hSpCas9	positive selection	4236321
129206505	129206528	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	0.49857040166503974	[2]	[3,3]	8	hSpCas9	positive selection	4299420
129206532	129206555	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.22064907194451316	[3]	[3,0]	-4	hSpCas9	positive selection	4299421
129205240	129205263	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.25593460560768033	[3]	[2,1]	-5	hSpCas9	positive selection	4299422
129205273	129205296	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.08529912260080816	[3]	[3,1]	-2	hSpCas9	positive selection	4363673
129189244	129189266	7	+	27760321	OCIAML3	viability	CTCGAGCGGGAACGCGACCGGG	SMO	ENSG00000128602	-0.304110774176531	[271,273]	[163,185]	-3	hSpCas9	negative selection	4441507
129189357	129189379	7	-	27760321	OCIAML3	viability	TTGTAGCGCAGCGGCTCGCAGG	SMO	ENSG00000128602	0.18115247605378199	[544,495]	[439,488]	2	hSpCas9	negative selection	4441508
129205252	129205274	7	-	27760321	OCIAML3	viability	GGGTTGTCTGTCCGAACCAAGG	SMO	ENSG00000128602	0.21730687261707066	[441,328]	[267,450]	2	hSpCas9	negative selection	4441509
129205369	129205391	7	+	27760321	OCIAML3	viability	CGGCCTTCGGGGCCGTCACGGG	SMO	ENSG00000128602	0.19018932811738282	[274,297]	[186,348]	2	hSpCas9	negative selection	4441510
129205729	129205751	7	-	27760321	OCIAML3	viability	ACGGCAGACGATCTCTCGGCGG	SMO	ENSG00000128602	1.170478655047318	[764,575]	[1104,1255]	9	hSpCas9	negative selection	4441511
129189244	129189266	7	+	27760321	OCIAML2	viability	CTCGAGCGGGAACGCGACCGGG	SMO	ENSG00000128602	-0.550966850436244	[271,273]	[130,177]	-6	hSpCas9	negative selection	4524970
129189357	129189379	7	-	27760321	OCIAML2	viability	TTGTAGCGCAGCGGCTCGCAGG	SMO	ENSG00000128602	0.023704519954823144	[544,495]	[353,524]	0	hSpCas9	negative selection	4524971
129205252	129205274	7	-	27760321	OCIAML2	viability	GGGTTGTCTGTCCGAACCAAGG	SMO	ENSG00000128602	0.12029522854168216	[441,328]	[313,364]	1	hSpCas9	negative selection	4524972
129205369	129205391	7	+	27760321	OCIAML2	viability	CGGCCTTCGGGGCCGTCACGGG	SMO	ENSG00000128602	0.5824920349489257	[274,297]	[278,441]	7	hSpCas9	negative selection	4524973
129205729	129205751	7	-	27760321	OCIAML2	viability	ACGGCAGACGATCTCTCGGCGG	SMO	ENSG00000128602	0.9311822429762757	[764,575]	[1045,998]	9	hSpCas9	negative selection	4524974
129189244	129189266	7	+	27760321	MV411	viability	CTCGAGCGGGAACGCGACCGGG	SMO	ENSG00000128602	-0.7680426218662487	[271,273]	[66,164]	-5	hSpCas9	negative selection	4608433
129189357	129189379	7	-	27760321	MV411	viability	TTGTAGCGCAGCGGCTCGCAGG	SMO	ENSG00000128602	-0.7442725405289222	[544,495]	[116,336]	-5	hSpCas9	negative selection	4608434
129205252	129205274	7	-	27760321	MV411	viability	GGGTTGTCTGTCCGAACCAAGG	SMO	ENSG00000128602	-0.001523731051226579	[441,328]	[131,431]	0	hSpCas9	negative selection	4608435
129205369	129205391	7	+	27760321	MV411	viability	CGGCCTTCGGGGCCGTCACGGG	SMO	ENSG00000128602	0.265525438731059	[274,297]	[181,298]	2	hSpCas9	negative selection	4608436
129205729	129205751	7	-	27760321	MV411	viability	ACGGCAGACGATCTCTCGGCGG	SMO	ENSG00000128602	1.3487680436018001	[764,575]	[1109,1128]	8	hSpCas9	negative selection	4608437
129189244	129189266	7	+	27760321	HL60	viability	CTCGAGCGGGAACGCGACCGGG	SMO	ENSG00000128602	-0.706053638339618	[271,273]	[126,147]	-6	hSpCas9	negative selection	4691896
129189357	129189379	7	-	27760321	HL60	viability	TTGTAGCGCAGCGGCTCGCAGG	SMO	ENSG00000128602	0.2413839977555131	[544,495]	[562,437]	3	hSpCas9	negative selection	4691897
129205252	129205274	7	-	27760321	HL60	viability	GGGTTGTCTGTCCGAACCAAGG	SMO	ENSG00000128602	-0.8002326512746663	[441,328]	[137,222]	-7	hSpCas9	negative selection	4691898
129205369	129205391	7	+	27760321	HL60	viability	CGGCCTTCGGGGCCGTCACGGG	SMO	ENSG00000128602	-0.17225095360028264	[274,297]	[177,241]	-2	hSpCas9	negative selection	4691899
129205729	129205751	7	-	27760321	HL60	viability	ACGGCAGACGATCTCTCGGCGG	SMO	ENSG00000128602	0.9485324282011891	[764,575]	[1007,1090]	8	hSpCas9	negative selection	4691900
129189244	129189266	7	+	27760321	HT1080	viability	CTCGAGCGGGAACGCGACCGGG	SMO	ENSG00000128602	0.3116353779933909	[273,213]	[70,174]	1	hSpCas9	negative selection	4775359
129189357	129189379	7	-	27760321	HT1080	viability	TTGTAGCGCAGCGGCTCGCAGG	SMO	ENSG00000128602	0.8194150119637893	[495,386]	[138,497]	4	hSpCas9	negative selection	4775360
129205252	129205274	7	-	27760321	HT1080	viability	GGGTTGTCTGTCCGAACCAAGG	SMO	ENSG00000128602	0.03714628444466206	[328,256]	[114,124]	0	hSpCas9	negative selection	4775361
129205369	129205391	7	+	27760321	HT1080	viability	CGGCCTTCGGGGCCGTCACGGG	SMO	ENSG00000128602	0.5167506606803174	[297,232]	[147,154]	2	hSpCas9	negative selection	4775362
129205729	129205751	7	-	27760321	HT1080	viability	ACGGCAGACGATCTCTCGGCGG	SMO	ENSG00000128602	0.43756501373435697	[575,449]	[166,396]	2	hSpCas9	negative selection	4775363
129189244	129189266	7	+	27760321	HT29	viability after 7 days	CTCGAGCGGGAACGCGACCGGG	SMO	ENSG00000128602	-0.2020313054920133	[273,213]	[241,348,223]	-3	hSpCas9	negative selection	4858822
129189357	129189379	7	-	27760321	HT29	viability after 7 days	TTGTAGCGCAGCGGCTCGCAGG	SMO	ENSG00000128602	-0.25177986300302724	[495,386]	[646,495,315]	-4	hSpCas9	negative selection	4858823
129205252	129205274	7	-	27760321	HT29	viability after 7 days	GGGTTGTCTGTCCGAACCAAGG	SMO	ENSG00000128602	0.756385801805284	[328,256]	[803,676,456]	9	hSpCas9	negative selection	4858824
129205369	129205391	7	+	27760321	HT29	viability after 7 days	CGGCCTTCGGGGCCGTCACGGG	SMO	ENSG00000128602	0.09277820906170181	[297,232]	[293,337,446]	1	hSpCas9	negative selection	4858825
129205729	129205751	7	-	27760321	HT29	viability after 7 days	ACGGCAGACGATCTCTCGGCGG	SMO	ENSG00000128602	0.32748654011769307	[575,449]	[789,905,781]	5	hSpCas9	negative selection	4858826
129189244	129189266	7	+	27760321	HT29	viability after 25 days	CTCGAGCGGGAACGCGACCGGG	SMO	ENSG00000128602	-0.6883038623541202	[273,213]	[194,153,167]	-5	hSpCas9	negative selection	4942285
129189357	129189379	7	-	27760321	HT29	viability after 25 days	TTGTAGCGCAGCGGCTCGCAGG	SMO	ENSG00000128602	-0.3544710925316057	[495,386]	[526,209,442]	-4	hSpCas9	negative selection	4942286
129205252	129205274	7	-	27760321	HT29	viability after 25 days	GGGTTGTCTGTCCGAACCAAGG	SMO	ENSG00000128602	0.512020012026293	[328,256]	[608,436,365]	5	hSpCas9	negative selection	4942287
129205369	129205391	7	+	27760321	HT29	viability after 25 days	CGGCCTTCGGGGCCGTCACGGG	SMO	ENSG00000128602	0.04435309453988706	[297,232]	[296,288,357]	0	hSpCas9	negative selection	4942288
129205729	129205751	7	-	27760321	HT29	viability after 25 days	ACGGCAGACGATCTCTCGGCGG	SMO	ENSG00000128602	0.3366493311348132	[575,449]	[1044,560,577]	3	hSpCas9	negative selection	4942289
129189244	129189266	7	+	27760321	HT29	viability after 22 days	CTCGAGCGGGAACGCGACCGGG	SMO	ENSG00000128602	-0.20765007206896102	[273,213]	[293,241,194]	-2	hSpCas9	negative selection	5025748
129189357	129189379	7	-	27760321	HT29	viability after 22 days	TTGTAGCGCAGCGGCTCGCAGG	SMO	ENSG00000128602	-0.14982423906920603	[495,386]	[462,459,456]	-1	hSpCas9	negative selection	5025749
129205252	129205274	7	-	27760321	HT29	viability after 22 days	GGGTTGTCTGTCCGAACCAAGG	SMO	ENSG00000128602	-0.03782970068993935	[328,256]	[350,343,293]	0	hSpCas9	negative selection	5025750
129205369	129205391	7	+	27760321	HT29	viability after 22 days	CGGCCTTCGGGGCCGTCACGGG	SMO	ENSG00000128602	-0.13621113499588083	[297,232]	[171,265,403]	-1	hSpCas9	negative selection	5025751
129205729	129205751	7	-	27760321	HT29	viability after 22 days	ACGGCAGACGATCTCTCGGCGG	SMO	ENSG00000128602	0.643816855779962	[575,449]	[1278,718,770]	7	hSpCas9	negative selection	5025752
129189244	129189266	7	+	27760321	HT29	viability after 19 days	CTCGAGCGGGAACGCGACCGGG	SMO	ENSG00000128602	-0.31642682223544205	[273,213]	[268,79,323]	-3	hSpCas9	negative selection	5109211
129189357	129189379	7	-	27760321	HT29	viability after 19 days	TTGTAGCGCAGCGGCTCGCAGG	SMO	ENSG00000128602	-0.3307829581480681	[495,386]	[627,282,319]	-3	hSpCas9	negative selection	5109212
129205252	129205274	7	-	27760321	HT29	viability after 19 days	GGGTTGTCTGTCCGAACCAAGG	SMO	ENSG00000128602	0.802673387463265	[328,256]	[689,454,617]	8	hSpCas9	negative selection	5109213
129205369	129205391	7	+	27760321	HT29	viability after 19 days	CGGCCTTCGGGGCCGTCACGGG	SMO	ENSG00000128602	0.010864809833228684	[297,232]	[176,602,130]	0	hSpCas9	negative selection	5109214
129205729	129205751	7	-	27760321	HT29	viability after 19 days	ACGGCAGACGATCTCTCGGCGG	SMO	ENSG00000128602	0.3916927480475	[575,449]	[1111,553,681]	4	hSpCas9	negative selection	5109215
129189244	129189266	7	+	27760321	HT29	viability after 16 days	CTCGAGCGGGAACGCGACCGGG	SMO	ENSG00000128602	-0.5986572985226946	[273,213]	[315,127,110]	-5	hSpCas9	negative selection	5192674
129189357	129189379	7	-	27760321	HT29	viability after 16 days	TTGTAGCGCAGCGGCTCGCAGG	SMO	ENSG00000128602	-0.47459505741572616	[495,386]	[253,193,612]	-5	hSpCas9	negative selection	5192675
129205252	129205274	7	-	27760321	HT29	viability after 16 days	GGGTTGTCTGTCCGAACCAAGG	SMO	ENSG00000128602	-0.0007680687181084722	[328,256]	[247,303,423]	0	hSpCas9	negative selection	5192676
129205369	129205391	7	+	27760321	HT29	viability after 16 days	CGGCCTTCGGGGCCGTCACGGG	SMO	ENSG00000128602	0.12437488349033954	[297,232]	[363,331,278]	1	hSpCas9	negative selection	5192677
129205729	129205751	7	-	27760321	HT29	viability after 16 days	ACGGCAGACGATCTCTCGGCGG	SMO	ENSG00000128602	0.30007784339657784	[575,449]	[994,522,633]	3	hSpCas9	negative selection	5192678
129189244	129189266	7	+	27760321	HT29	viability after 13 days	CTCGAGCGGGAACGCGACCGGG	SMO	ENSG00000128602	-0.06980271082571499	[273,213]	[240,278,287]	-1	hSpCas9	negative selection	5276137
129189357	129189379	7	-	27760321	HT29	viability after 13 days	TTGTAGCGCAGCGGCTCGCAGG	SMO	ENSG00000128602	-0.6167002803464328	[495,386]	[336,313,349]	-6	hSpCas9	negative selection	5276138
129205252	129205274	7	-	27760321	HT29	viability after 13 days	GGGTTGTCTGTCCGAACCAAGG	SMO	ENSG00000128602	0.47071904871491743	[328,256]	[708,341,367]	6	hSpCas9	negative selection	5276139
129205369	129205391	7	+	27760321	HT29	viability after 13 days	CGGCCTTCGGGGCCGTCACGGG	SMO	ENSG00000128602	-0.08938325269905584	[297,232]	[348,307,215]	-1	hSpCas9	negative selection	5276140
129205729	129205751	7	-	27760321	HT29	viability after 13 days	ACGGCAGACGATCTCTCGGCGG	SMO	ENSG00000128602	0.48657330490382633	[575,449]	[1217,539,747]	6	hSpCas9	negative selection	5276141
129189244	129189266	7	+	27760321	HT29	viability after 10 days	CTCGAGCGGGAACGCGACCGGG	SMO	ENSG00000128602	-0.44929333882330114	[273,213]	[184,292,193]	-5	hSpCas9	negative selection	5359600
129189357	129189379	7	-	27760321	HT29	viability after 10 days	TTGTAGCGCAGCGGCTCGCAGG	SMO	ENSG00000128602	-0.16536657666957957	[495,386]	[581,520,374]	-2	hSpCas9	negative selection	5359601
129205252	129205274	7	-	27760321	HT29	viability after 10 days	GGGTTGTCTGTCCGAACCAAGG	SMO	ENSG00000128602	0.6348313281670187	[328,256]	[687,491,522]	8	hSpCas9	negative selection	5359602
129205369	129205391	7	+	27760321	HT29	viability after 10 days	CGGCCTTCGGGGCCGTCACGGG	SMO	ENSG00000128602	-0.8259245922767566	[297,232]	[191,143,222]	-7	hSpCas9	negative selection	5359603
129205729	129205751	7	-	27760321	HT29	viability after 10 days	ACGGCAGACGATCTCTCGGCGG	SMO	ENSG00000128602	0.037208611436582606	[575,449]	[731,628,610]	0	hSpCas9	negative selection	5359604
129189244	129189266	7	+	27760321	MOLM13	viability	CTCGAGCGGGAACGCGACCGGG	SMO	ENSG00000128602	0.22537115864501817	[271,273]	[271,102]	1	hSpCas9	negative selection	5443063
129189357	129189379	7	-	27760321	MOLM13	viability	TTGTAGCGCAGCGGCTCGCAGG	SMO	ENSG00000128602	0.9065585019715807	[544,495]	[641,471]	6	hSpCas9	negative selection	5443064
129205252	129205274	7	-	27760321	MOLM13	viability	GGGTTGTCTGTCCGAACCAAGG	SMO	ENSG00000128602	1.3045367983351068	[441,328]	[168,841]	8	hSpCas9	negative selection	5443065
129205369	129205391	7	+	27760321	MOLM13	viability	CGGCCTTCGGGGCCGTCACGGG	SMO	ENSG00000128602	-0.05304633891345445	[274,297]	[185,131]	0	hSpCas9	negative selection	5443066
129205729	129205751	7	-	27760321	MOLM13	viability	ACGGCAGACGATCTCTCGGCGG	SMO	ENSG00000128602	1.4728777101305819	[764,575]	[686,1342]	8	hSpCas9	negative selection	5443067
129189017	129189040	7	+	27661255	K562	viability	GGCCCGGGCCCGGATTCTCTGGG	SMO	ENSG00000128602	-0.12960881094968768	[441,380]	[317,286]	-4	dCas9-KRAB	negative selection	5513030
129189069	129189092	7	-	27661255	K562	viability	GGCCACACGCACGACCTCGGCGG	SMO	ENSG00000128602	0.19830211215142535	[744,869]	[737,737]	6	dCas9-KRAB	negative selection	5513031
129206505	129206528	7	+	27260156	BXPC3	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.4059014443156794	[452]	[371,384,310,354]	-7	hSpCas9	negative selection	5571880
129206532	129206555	7	+	27260156	BXPC3	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.013124402873023897	[483]	[536,443,514,548]	0	hSpCas9	negative selection	5571881
129205240	129205263	7	+	27260156	BXPC3	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.35644179640993934	[728]	[510,476,677,747]	-7	hSpCas9	negative selection	5571882
129205273	129205296	7	-	27260156	BXPC3	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.09717918791042962	[513]	[469,589,409,536]	-2	hSpCas9	negative selection	5636133
129206505	129206528	7	+	27260156	A673	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.3335174887847895	[452]	[512,471,305,444]	-7	hSpCas9	negative selection	5693131
129206532	129206555	7	+	27260156	A673	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.10975256122877378	[483]	[749,552,571,649]	2	hSpCas9	negative selection	5693132
129205240	129205263	7	+	27260156	A673	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.2807980964742304	[728]	[751,662,727,743]	-6	hSpCas9	negative selection	5693133
129205273	129205296	7	-	27260156	A673	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.02484228548502493	[513]	[759,576,526,578]	0	hSpCas9	negative selection	5757384
129206505	129206528	7	+	27260156	A375	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.06159538566914063	[452]	[739,690,343,302]	-1	hSpCas9	negative selection	5814382
129206532	129206555	7	+	27260156	A375	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.15537926092426962	[483]	[267,964,725,603]	2	hSpCas9	negative selection	5814383
129205240	129205263	7	+	27260156	A375	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.9616033569015354	[728]	[397,498,453,407]	-8	hSpCas9	negative selection	5814384
129205273	129205296	7	-	27260156	A375	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.271445364558911	[513]	[485,514,371,603]	-4	hSpCas9	negative selection	5878635
129206505	129206528	7	+	27260156	COLO741	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.5805245742022146	[452]	[389,361,406]	-8	hSpCas9	negative selection	5935633
129206532	129206555	7	+	27260156	COLO741	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.20747534418237112	[483]	[494,624,485]	-4	hSpCas9	negative selection	5935634
129205240	129205263	7	+	27260156	COLO741	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.4479078881685822	[728]	[789,737,538]	-7	hSpCas9	negative selection	5935635
129205273	129205296	7	-	27260156	COLO741	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.0995576419835415	[513]	[732,676,449]	-2	hSpCas9	negative selection	5999886
129206505	129206528	7	+	27260156	CAL120	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	0.0008304871287887483	[452]	[577,553,561]	0	hSpCas9	negative selection	6056884
129206532	129206555	7	+	27260156	CAL120	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.062108547387698464	[483]	[443,550,712]	-1	hSpCas9	negative selection	6056885
129205240	129205263	7	+	27260156	CAL120	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.48914511995114707	[728]	[631,630,672]	-6	hSpCas9	negative selection	6056886
129205273	129205296	7	-	27260156	CAL120	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.263098483553034	[513]	[699,397,525]	-4	hSpCas9	negative selection	6121137
129206505	129206528	7	+	27260156	CADOES1	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.2902225508532144	[452]	[313,420,283,359]	-5	hSpCas9	negative selection	6178135
129206532	129206555	7	+	27260156	CADOES1	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.05516000634662194	[483]	[605,505,329,426]	1	hSpCas9	negative selection	6178136
129205240	129205263	7	+	27260156	CADOES1	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.5204227152058958	[728]	[427,395,432,639]	-7	hSpCas9	negative selection	6178137
129205273	129205296	7	-	27260156	CADOES1	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.3199295024685943	[513]	[589,709,495,590]	5	hSpCas9	negative selection	6242388
129206505	129206528	7	+	27260156	EWS502	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.4084332501979733	[452]	[242,269,509,447]	-6	hSpCas9	negative selection	6299386
129206532	129206555	7	+	27260156	EWS502	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.1742525291661715	[483]	[260,565,470,542]	-3	hSpCas9	negative selection	6299387
129205240	129205263	7	+	27260156	EWS502	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.3027057738069355	[728]	[562,575,762,609]	-5	hSpCas9	negative selection	6299388
129205273	129205296	7	-	27260156	EWS502	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.03877251700573561	[513]	[658,413,502,658]	0	hSpCas9	negative selection	6363639
129206505	129206528	7	+	27260156	EW8	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.5675542701219151	[452]	[336,181,263,213]	-8	hSpCas9	negative selection	6420637
129206532	129206555	7	+	27260156	EW8	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.1716768875051068	[483]	[416,492,456,393]	3	hSpCas9	negative selection	6420638
129205240	129205263	7	+	27260156	EW8	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.43704687746998927	[728]	[559,592,300,327]	-7	hSpCas9	negative selection	6420639
129205273	129205296	7	-	27260156	EW8	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.20284548413876646	[513]	[413,495,353,665]	4	hSpCas9	negative selection	6484890
129206505	129206528	7	+	27260156	CORL105	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.5438600773942268	[452]	[336,441,396,281]	-7	hSpCas9	negative selection	6541888
129206532	129206555	7	+	27260156	CORL105	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.35975887482944324	[483]	[726,747,734,698]	6	hSpCas9	negative selection	6541889
129205240	129205263	7	+	27260156	CORL105	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.30589829297334287	[728]	[828,603,740,601]	-5	hSpCas9	negative selection	6541890
129205273	129205296	7	-	27260156	CORL105	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.14849646512746836	[513]	[657,482,544,490]	-3	hSpCas9	negative selection	6606141
129206505	129206528	7	+	27260156	HS294T	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.23801235408517404	[452]	[111,76,99,342]	-3	hSpCas9	negative selection	6663139
129206532	129206555	7	+	27260156	HS294T	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.24447508989501107	[483]	[234,176,218,261]	3	hSpCas9	negative selection	6663140
129205240	129205263	7	+	27260156	HS294T	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.3086087434932169	[728]	[136,144,192,489]	-4	hSpCas9	negative selection	6663141
129205273	129205296	7	-	27260156	HS294T	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.3557892753320554	[513]	[201,118,142,152]	-5	hSpCas9	negative selection	6727392
129206505	129206528	7	+	27260156	HCC44	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.4953336864893758	[452]	[469,306,444,263]	-6	hSpCas9	negative selection	6784390
129206532	129206555	7	+	27260156	HCC44	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.14964697829617912	[483]	[596,795,632,381]	2	hSpCas9	negative selection	6784391
129205240	129205263	7	+	27260156	HCC44	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.06689242782969129	[728]	[777,643,860,887]	-1	hSpCas9	negative selection	6784392
129205273	129205296	7	-	27260156	HCC44	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.16635818861110296	[513]	[992,516,492,624]	2	hSpCas9	negative selection	6848643
129206505	129206528	7	+	27260156	G402	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.020172145576373333	[452]	[336,1325,376,171]	0	hSpCas9	negative selection	6905641
129206532	129206555	7	+	27260156	G402	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.1622977256761675	[483]	[444,617,748,788]	2	hSpCas9	negative selection	6905642
129205240	129205263	7	+	27260156	G402	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.7491352649755341	[728]	[476,461,710,456]	-7	hSpCas9	negative selection	6905643
129205273	129205296	7	-	27260156	G402	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.028473921824995738	[513]	[926,497,633,444]	0	hSpCas9	negative selection	6969894
129206505	129206528	7	+	27260156	L33	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.5571775351499887	[452]	[245,132,234,288]	-8	hSpCas9	negative selection	7026892
129206532	129206555	7	+	27260156	L33	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.4083623380510043	[483]	[613,283,423,588]	8	hSpCas9	negative selection	7026893
129205240	129205263	7	+	27260156	L33	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.08879032983545265	[728]	[533,284,488,737]	-2	hSpCas9	negative selection	7026894
129205273	129205296	7	-	27260156	L33	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.010275120433385646	[513]	[531,184,331,528]	0	hSpCas9	negative selection	7091145
129206505	129206528	7	+	27260156	K562	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-1.061136038995355	[452]	[220,222,214,122]	-8	hSpCas9	negative selection	7148143
129206532	129206555	7	+	27260156	K562	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.5516243808388286	[483]	[317,172,253,407]	-6	hSpCas9	negative selection	7148144
129205240	129205263	7	+	27260156	K562	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.298280709417614	[728]	[370,479,586,635]	-4	hSpCas9	negative selection	7148145
129205273	129205296	7	-	27260156	K562	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.779153313027219	[513]	[418,99,451,112]	-7	hSpCas9	negative selection	7212396
129206505	129206528	7	+	27260156	HT29	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.48937775971186315	[452]	[441,440,386,313]	-7	hSpCas9	negative selection	7269394
129206532	129206555	7	+	27260156	HT29	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.026787416745172404	[483]	[848,664,600,335]	0	hSpCas9	negative selection	7269395
129205240	129205263	7	+	27260156	HT29	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.23796507384717502	[728]	[776,656,771,783]	-5	hSpCas9	negative selection	7269396
129205273	129205296	7	-	27260156	HT29	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.228962791381141	[513]	[842,796,808,515]	4	hSpCas9	negative selection	7333647
129206505	129206528	7	+	27260156	MHHES1	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.4562692374225181	[452]	[426,359,370,334]	-7	hSpCas9	negative selection	7390645
129206532	129206555	7	+	27260156	MHHES1	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.16195229954099769	[483]	[682,643,586,539]	3	hSpCas9	negative selection	7390646
129205240	129205263	7	+	27260156	MHHES1	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.2953500719856504	[728]	[674,866,650,522]	-5	hSpCas9	negative selection	7390647
129205273	129205296	7	-	27260156	MHHES1	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.22250830108334996	[513]	[610,489,602,323]	-4	hSpCas9	negative selection	7454898
129206505	129206528	7	+	27260156	MEWO	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.17413427650972824	[452]	[502,264,383]	-4	hSpCas9	negative selection	7511896
129206532	129206555	7	+	27260156	MEWO	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.06736078595071691	[483]	[505,365,438]	-1	hSpCas9	negative selection	7511897
129205240	129205263	7	+	27260156	MEWO	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	0.028326341239844233	[728]	[814,619,674]	0	hSpCas9	negative selection	7511898
129205273	129205296	7	-	27260156	MEWO	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.13731117935239928	[513]	[504,374,444]	-3	hSpCas9	negative selection	7576149
129206505	129206528	7	+	27260156	LNCAPCLONEFGC	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.03399657274605538	[452]	[317,453,265,542]	0	hSpCas9	negative selection	7633147
129206532	129206555	7	+	27260156	LNCAPCLONEFGC	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.036946868736287275	[483]	[405,317,610,408]	0	hSpCas9	negative selection	7633148
129205240	129205263	7	+	27260156	LNCAPCLONEFGC	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.7106129774438754	[728]	[393,361,512,363]	-8	hSpCas9	negative selection	7633149
129205273	129205296	7	-	27260156	LNCAPCLONEFGC	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.1877799247951607	[513]	[637,445,533,506]	3	hSpCas9	negative selection	7697400
129206505	129206528	7	+	27260156	PANC0327	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.5347784830409325	[452]	[502,155,188,296]	-6	hSpCas9	negative selection	7754398
129206532	129206555	7	+	27260156	PANC0327	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.15687196492847832	[483]	[429,299,337,488]	-2	hSpCas9	negative selection	7754399
129205240	129205263	7	+	27260156	PANC0327	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.49294679088258575	[728]	[469,435,301,635]	-6	hSpCas9	negative selection	7754400
129205273	129205296	7	-	27260156	PANC0327	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.7134253303353082	[513]	[1197,387,810,680]	8	hSpCas9	negative selection	7818651
129206505	129206528	7	+	27260156	NCIH2009	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.23249892242104855	[452]	[658,482,497]	-3	hSpCas9	negative selection	7875649
129206532	129206555	7	+	27260156	NCIH2009	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.32462668290950714	[483]	[1045,874,656]	4	hSpCas9	negative selection	7875650
129205240	129205263	7	+	27260156	NCIH2009	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.8074307710296948	[728]	[684,544,535]	-7	hSpCas9	negative selection	7875651
129205273	129205296	7	-	27260156	NCIH2009	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.2656964568405582	[513]	[857,461,524]	-4	hSpCas9	negative selection	7939902
129206505	129206528	7	+	27260156	NCIH1373	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.8884240249435131	[452]	[237,353,142,92]	-7	hSpCas9	negative selection	7996900
129206532	129206555	7	+	27260156	NCIH1373	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.24315444048887766	[483]	[892,641,489,151]	2	hSpCas9	negative selection	7996901
129205240	129205263	7	+	27260156	NCIH1373	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-1.0971055616352772	[728]	[588,365,307,76]	-8	hSpCas9	negative selection	7996902
129205273	129205296	7	-	27260156	NCIH1373	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.7492454679589109	[513]	[890,507,681,495]	7	hSpCas9	negative selection	8061153
129206505	129206528	7	+	27260156	PATU8902	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.5238492849806317	[452]	[607,638,125,460]	-5	hSpCas9	negative selection	8118151
129206532	129206555	7	+	27260156	PATU8902	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.20933886548061892	[483]	[499,679,808,239]	-2	hSpCas9	negative selection	8118152
129205240	129205263	7	+	27260156	PATU8902	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.19175007007205347	[728]	[697,592,1179,1018]	-2	hSpCas9	negative selection	8118153
129205273	129205296	7	-	27260156	PATU8902	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.20854475314717755	[513]	[783,963,231,588]	-2	hSpCas9	negative selection	8182404
129206505	129206528	7	+	27260156	PANC1	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.8496436158570457	[452]	[147,326,264,154]	-8	hSpCas9	negative selection	8239402
129206532	129206555	7	+	27260156	PANC1	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.03705367172903814	[483]	[451,369,474,322]	0	hSpCas9	negative selection	8239403
129205240	129205263	7	+	27260156	PANC1	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.4385787170690154	[728]	[574,560,506,250]	-6	hSpCas9	negative selection	8239404
129205273	129205296	7	-	27260156	PANC1	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.03614542692887665	[513]	[345,513,581,387]	0	hSpCas9	negative selection	8303655
129206505	129206528	7	+	27260156	PANC0813	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.01723666352963909	[452]	[667,552,407,487]	0	hSpCas9	negative selection	8360653
129206532	129206555	7	+	27260156	PANC0813	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.6863372288345219	[483]	[879,965,1037,778]	9	hSpCas9	negative selection	8360654
129205240	129205263	7	+	27260156	PANC0813	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.22020326343491853	[728]	[785,626,997,544]	-4	hSpCas9	negative selection	8360655
129205273	129205296	7	-	27260156	PANC0813	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.2645937993627196	[513]	[626,519,466,411]	-4	hSpCas9	negative selection	8424906
129206505	129206528	7	+	27260156	RDES	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.34349432993587037	[452]	[375,363,340,583]	-5	hSpCas9	negative selection	8481904
129206532	129206555	7	+	27260156	RDES	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.11986309134281437	[483]	[588,447,759,630]	2	hSpCas9	negative selection	8481905
129205240	129205263	7	+	27260156	RDES	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.714474155972673	[728]	[372,508,627,560]	-8	hSpCas9	negative selection	8481906
129205273	129205296	7	-	27260156	RDES	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.01598876163740312	[513]	[490,504,645,794]	0	hSpCas9	negative selection	8546157
129206505	129206528	7	+	27260156	PC3	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.2033145401843605	[452]	[323,320,586,397]	-4	hSpCas9	negative selection	8603155
129206532	129206555	7	+	27260156	PC3	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.018138978576273793	[483]	[268,411,911,537]	0	hSpCas9	negative selection	8603156
129205240	129205263	7	+	27260156	PC3	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.21614787201504765	[728]	[404,741,827,631]	-5	hSpCas9	negative selection	8603157
129205273	129205296	7	-	27260156	PC3	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.11510728875997114	[513]	[297,604,908,609]	2	hSpCas9	negative selection	8667408
129206505	129206528	7	+	27260156	PATU8988T	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.2893315672757004	[452]	[374,301,410,336]	-5	hSpCas9	negative selection	8724406
129206532	129206555	7	+	27260156	PATU8988T	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.5477326043391733	[483]	[566,809,590,787]	8	hSpCas9	negative selection	8724407
129205240	129205263	7	+	27260156	PATU8988T	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.331679311770803	[728]	[411,403,935,458]	-5	hSpCas9	negative selection	8724408
129205273	129205296	7	-	27260156	PATU8988T	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.1784074369450033	[513]	[365,448,575,356]	-3	hSpCas9	negative selection	8788659
129206505	129206528	7	+	27260156	T47D	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.4327065047853938	[452]	[398,384,376,403]	-7	hSpCas9	negative selection	8845657
129206532	129206555	7	+	27260156	T47D	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	-0.07986346451854191	[483]	[517,504,486,629]	-2	hSpCas9	negative selection	8845658
129205240	129205263	7	+	27260156	T47D	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.2519302235249226	[728]	[714,636,689,820]	-5	hSpCas9	negative selection	8845659
129205273	129205296	7	-	27260156	T47D	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.11825720565915815	[513]	[496,524,700,480]	-3	hSpCas9	negative selection	8909910
129206505	129206528	7	+	27260156	SU8686	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.3082585725006253	[452]	[348,258,408,463]	-5	hSpCas9	negative selection	8966908
129206532	129206555	7	+	27260156	SU8686	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.48463088786231023	[483]	[607,634,735,723]	7	hSpCas9	negative selection	8966909
129205240	129205263	7	+	27260156	SU8686	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.19938458402558557	[728]	[643,486,574,859]	-3	hSpCas9	negative selection	8966910
129205273	129205296	7	-	27260156	SU8686	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.05623752621065092	[513]	[482,403,536,556]	-1	hSpCas9	negative selection	9031161
129206505	129206528	7	+	27260156	SKES1	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.13075082789485046	[452]	[442,399,409,397]	-3	hSpCas9	negative selection	9088159
129206532	129206555	7	+	27260156	SKES1	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.13105791188530552	[483]	[742,642,422,364]	3	hSpCas9	negative selection	9088160
129205240	129205263	7	+	27260156	SKES1	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.32386949442772306	[728]	[712,728,529,403]	-6	hSpCas9	negative selection	9088161
129205273	129205296	7	-	27260156	SKES1	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.11855885070936573	[513]	[529,567,475,344]	-3	hSpCas9	negative selection	9152412
129206505	129206528	7	+	27260156	TOV112D	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.12827795031376688	[452]	[630,294,330,391]	-2	hSpCas9	negative selection	9209410
129206532	129206555	7	+	27260156	TOV112D	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.14540152688539937	[483]	[494,729,391,569]	3	hSpCas9	negative selection	9209411
129205240	129205263	7	+	27260156	TOV112D	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.30144988940199324	[728]	[338,1135,476,530]	-5	hSpCas9	negative selection	9209412
129205273	129205296	7	-	27260156	TOV112D	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.05295777494501738	[513]	[700,724,404,369]	1	hSpCas9	negative selection	9273663
129206505	129206528	7	+	27260156	TC71	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.2963386319812775	[452]	[358,475,341,407]	-7	hSpCas9	negative selection	9330661
129206532	129206555	7	+	27260156	TC71	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.12143538826692934	[483]	[728,367,669,477]	3	hSpCas9	negative selection	9330662
129205240	129205263	7	+	27260156	TC71	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.19119703535428328	[728]	[652,692,574,829]	-5	hSpCas9	negative selection	9330663
129205273	129205296	7	-	27260156	TC71	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	0.12097941750061558	[513]	[568,587,569,675]	3	hSpCas9	negative selection	9394914
129206505	129206528	7	+	27260156	TC32	viability	CAAGAACTACCGATACCGTGCGG	SMO	ENSG00000128602	-0.36159835663709294	[452]	[442,220,457,225]	-6	hSpCas9	negative selection	9451912
129206532	129206555	7	+	27260156	TC32	viability	CGTGCTGGCCCCAATCGGCCTGG	SMO	ENSG00000128602	0.38197008086508044	[483]	[483,657,724,468]	6	hSpCas9	negative selection	9451913
129205240	129205263	7	+	27260156	TC32	viability	AGTGCGAAGTGCCCTTGGTTCGG	SMO	ENSG00000128602	-0.396220285739593	[728]	[370,438,814,527]	-6	hSpCas9	negative selection	9451914
129205273	129205296	7	-	27260156	TC32	viability	CACGTCCTCGTACCAGCTCTTGG	SMO	ENSG00000128602	-0.13677401613705345	[513]	[386,282,588,572]	-2	hSpCas9	negative selection	9516165
129189356	129189379	7	-	27869803	HPAFII	viability after 27 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	0.47083792326604623	[200]	[128,160,NaN]	4	hSpCas9	negative selection	9597988
129203514	129203537	7	+	27869803	HPAFII	viability after 27 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	0.6951480572880143	[200]	[133,201,NaN]	5	hSpCas9	negative selection	9597989
129205328	129205351	7	+	27869803	HPAFII	viability after 27 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.06369467531738962	[248]	[108,159,NaN]	0	hSpCas9	negative selection	9597990
129205728	129205751	7	-	27869803	HPAFII	viability after 27 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	1.0208571374549356	[48]	[60,44,NaN]	8	hSpCas9	negative selection	9597991
129206167	129206190	7	-	27869803	HPAFII	viability after 27 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	0.22131165743241388	[92]	[20,86,NaN]	1	hSpCas9	negative selection	9597992
129206550	129206573	7	-	27869803	HPAFII	viability after 27 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	1.2580867047186006	[124]	[190,128,NaN]	8	hSpCas9	negative selection	9597993
129189356	129189379	7	-	27869803	HPAFII	viability after 15 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	-0.18240943213240624	[200]	[161,207,NaN]	-2	hSpCas9	negative selection	9680437
129203514	129203537	7	+	27869803	HPAFII	viability after 15 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	0.04960676200497566	[200]	[164,259,NaN]	0	hSpCas9	negative selection	9680438
129205328	129205351	7	+	27869803	HPAFII	viability after 15 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	-0.11517562783574244	[248]	[325,197,NaN]	-1	hSpCas9	negative selection	9680439
129205728	129205751	7	-	27869803	HPAFII	viability after 15 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	1.4285297879836993	[48]	[150,135,NaN]	9	hSpCas9	negative selection	9680440
129206167	129206190	7	-	27869803	HPAFII	viability after 15 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	0.18229207805708247	[92]	[60,145,NaN]	2	hSpCas9	negative selection	9680441
129206550	129206573	7	-	27869803	HPAFII	viability after 15 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	0.5009285567269492	[124]	[289,127,NaN]	6	hSpCas9	negative selection	9680442
129189356	129189379	7	-	27869803	ASPC1	viability after 36 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	1.2879981276797292	[351]	[252,115,475]	9	hSpCas9	negative selection	9762886
129203514	129203537	7	+	27869803	ASPC1	viability after 36 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	0.6481211394330867	[640]	[592,12,444]	6	hSpCas9	negative selection	9762887
129205328	129205351	7	+	27869803	ASPC1	viability after 36 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	-0.6291300948938643	[609]	[52,271,88]	-6	hSpCas9	negative selection	9762888
129205728	129205751	7	-	27869803	ASPC1	viability after 36 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	-0.2249770362515996	[322]	[63,126,93]	-2	hSpCas9	negative selection	9762889
129206167	129206190	7	-	27869803	ASPC1	viability after 36 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	0.9254530385314753	[169]	[246,34,78]	8	hSpCas9	negative selection	9762890
129206550	129206573	7	-	27869803	ASPC1	viability after 36 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	0.4266645070780608	[214]	[175,32,100]	4	hSpCas9	negative selection	9762891
129189356	129189379	7	-	27869803	PATU8988S	viability after 35 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	-0.2476186620143981	[475]	[149,172,NaN]	-3	hSpCas9	negative selection	9845335
129203514	129203537	7	+	27869803	PATU8988S	viability after 35 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	0.86176339192753	[370]	[286,255,NaN]	8	hSpCas9	negative selection	9845336
129205328	129205351	7	+	27869803	PATU8988S	viability after 35 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.4621397431784937	[657]	[396,332,NaN]	5	hSpCas9	negative selection	9845337
129205728	129205751	7	-	27869803	PATU8988S	viability after 35 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	-0.2929620254210539	[282]	[106,78,NaN]	-3	hSpCas9	negative selection	9845338
129206167	129206190	7	-	27869803	PATU8988S	viability after 35 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-1.6529657802095463	[116]	[7,21,NaN]	-8	hSpCas9	negative selection	9845339
129206550	129206573	7	-	27869803	PATU8988S	viability after 35 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	-0.46870747999886064	[248]	[57,86,NaN]	-5	hSpCas9	negative selection	9845340
129189356	129189379	7	-	27869803	PATU8988S	viability after 31 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	-0.042674412095541125	[475]	[134,246,NaN]	0	hSpCas9	negative selection	9927784
129203514	129203537	7	+	27869803	PATU8988S	viability after 31 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	0.533667390387685	[370]	[163,277,NaN]	6	hSpCas9	negative selection	9927785
129205328	129205351	7	+	27869803	PATU8988S	viability after 31 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.46323018508549985	[657]	[333,396,NaN]	5	hSpCas9	negative selection	9927786
129205728	129205751	7	-	27869803	PATU8988S	viability after 31 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	-0.6840092350240725	[282]	[60,81,NaN]	-6	hSpCas9	negative selection	9927787
129206167	129206190	7	-	27869803	PATU8988S	viability after 31 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	-0.09117301149208679	[116]	[23,68,NaN]	-1	hSpCas9	negative selection	9927788
129206550	129206573	7	-	27869803	PATU8988S	viability after 31 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	-0.4085158939414886	[248]	[87,57,NaN]	-4	hSpCas9	negative selection	9927789
129189356	129189379	7	-	27869803	HPAFII	viability after 35 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	-0.6458936678764806	[200]	[9,126,NaN]	-4	hSpCas9	negative selection	10010233
129203514	129203537	7	+	27869803	HPAFII	viability after 35 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	0.22551915365786307	[200]	[62,181,NaN]	1	hSpCas9	negative selection	10010234
129205328	129205351	7	+	27869803	HPAFII	viability after 35 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	-0.23745931534279813	[248]	[73,143,NaN]	-1	hSpCas9	negative selection	10010235
129205728	129205751	7	-	27869803	HPAFII	viability after 35 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	1.378031194203753	[48]	[71,55,NaN]	8	hSpCas9	negative selection	10010236
129206167	129206190	7	-	27869803	HPAFII	viability after 35 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	0.06251905528061585	[92]	[27,72,NaN]	0	hSpCas9	negative selection	10010237
129206550	129206573	7	-	27869803	HPAFII	viability after 35 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	-0.23813100857300706	[124]	[63,41,NaN]	-1	hSpCas9	negative selection	10010238
129189356	129189379	7	-	27869803	HPAFII	viability after 31 days	TTGTAGCGCAGCGGCTCGCAGGG	SMO	ENSG00000128602	-0.21214806060192726	[200]	[49,148,NaN]	-1	hSpCas9	negative selection	10092682
129203514	129203537	7	+	27869803	HPAFII	viability after 31 days	TGCCATCGTGGAGAGGGAGCGGG	SMO	ENSG00000128602	0.447030180455182	[200]	[92,219,NaN]	3	hSpCas9	negative selection	10092683
129205328	129205351	7	+	27869803	HPAFII	viability after 31 days	CTTCACAGAGGCTGAGCACCAGG	SMO	ENSG00000128602	0.19239617609221446	[248]	[185,130,NaN]	1	hSpCas9	negative selection	10092684
129205728	129205751	7	-	27869803	HPAFII	viability after 31 days	ACGGCAGACGATCTCTCGGCGGG	SMO	ENSG00000128602	1.9745027057191824	[48]	[64,154,NaN]	9	hSpCas9	negative selection	10092685
129206167	129206190	7	-	27869803	HPAFII	viability after 31 days	GATGACAAAGATGATGACGCAGG	SMO	ENSG00000128602	0.11676045851050909	[92]	[13,102,NaN]	0	hSpCas9	negative selection	10092686
129206550	129206573	7	-	27869803	HPAFII	viability after 31 days	AGCCTCCCACGATGAGCACCAGG	SMO	ENSG00000128602	0.153253339542468	[124]	[55,101,NaN]	1	hSpCas9	negative selection	10092687
129203448	129203471	7	+	28162770	P31FUJ	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	-0.20632999305318744	[53]	[54]	-2	hSpCas9	negative selection	10239377
129203400	129203423	7	-	28162770	P31FUJ	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	-0.8689900284907078	[128]	[82]	-6	hSpCas9	negative selection	10239378
129203422	129203445	7	-	28162770	P31FUJ	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	-0.0217785971571281	[272]	[315]	0	hSpCas9	negative selection	10239379
129205238	129205261	7	-	28162770	P31FUJ	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-1.4400082219361505	[440]	[190]	-7	hSpCas9	negative selection	10239380
129205261	129205284	7	+	28162770	P31FUJ	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	-0.8848789009940723	[21]	[13]	-6	hSpCas9	negative selection	10239381
129205277	129205300	7	+	28162770	P31FUJ	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-1.3452769336727914	[239]	[110]	-7	hSpCas9	negative selection	10239382
129206309	129206332	7	-	28162770	P31FUJ	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	-0.07526092742789864	[155]	[173]	0	hSpCas9	negative selection	10239383
129203448	129203471	7	+	28162770	TF1	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10408743
129203400	129203423	7	-	28162770	TF1	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10408744
129203422	129203445	7	-	28162770	TF1	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10408745
129205238	129205261	7	-	28162770	TF1	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	NaN	[NaN]	[133]	1	hSpCas9	negative selection	10408746
129205261	129205284	7	+	28162770	TF1	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	NaN	[NaN]	[51]	1	hSpCas9	negative selection	10408747
129205277	129205300	7	+	28162770	TF1	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10408748
129206309	129206332	7	-	28162770	TF1	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10408749
129203448	129203471	7	+	28162770	SKM1	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	0.3656253051537657	[17]	[40]	3	hSpCas9	negative selection	10578109
129203400	129203423	7	-	28162770	SKM1	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	-0.3439544012173614	[27]	[38]	-3	hSpCas9	negative selection	10578110
129203422	129203445	7	-	28162770	SKM1	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	-0.03350580321571728	[76]	[132]	0	hSpCas9	negative selection	10578111
129205238	129205261	7	-	28162770	SKM1	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-0.6104975928282936	[132]	[153]	-5	hSpCas9	negative selection	10578112
129205261	129205284	7	+	28162770	SKM1	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	1.4581062211707299	[6]	[33]	9	hSpCas9	negative selection	10578113
129205277	129205300	7	+	28162770	SKM1	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-0.21933719556739037	[53]	[81]	-2	hSpCas9	negative selection	10578114
129206309	129206332	7	-	28162770	SKM1	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	0.14147242595288034	[19]	[38]	1	hSpCas9	negative selection	10578115
129203448	129203471	7	+	28162770	SKM1	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	0.3656253051537657	[17]	[40]	3	hSpCas9	negative selection	10747475
129203400	129203423	7	-	28162770	SKM1	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	-0.3439544012173614	[27]	[38]	-3	hSpCas9	negative selection	10747476
129203422	129203445	7	-	28162770	SKM1	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	-0.03350580321571728	[76]	[132]	0	hSpCas9	negative selection	10747477
129205238	129205261	7	-	28162770	SKM1	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-0.6104975928282936	[132]	[153]	-5	hSpCas9	negative selection	10747478
129205261	129205284	7	+	28162770	SKM1	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	1.4581062211707299	[6]	[33]	9	hSpCas9	negative selection	10747479
129205277	129205300	7	+	28162770	SKM1	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-0.21933719556739037	[53]	[81]	-2	hSpCas9	negative selection	10747480
129206309	129206332	7	-	28162770	SKM1	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	0.14147242595288034	[19]	[38]	1	hSpCas9	negative selection	10747481
129203448	129203471	7	+	28162770	PL21	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	0.12975028659792187	[41]	[19]	1	hSpCas9	negative selection	10916841
129203400	129203423	7	-	28162770	PL21	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	-0.7409666964571113	[95]	[24]	-5	hSpCas9	negative selection	10916842
129203422	129203445	7	-	28162770	PL21	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	0.02081591504475805	[230]	[101]	0	hSpCas9	negative selection	10916843
129205238	129205261	7	-	28162770	PL21	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-0.716411092169768	[486]	[128]	-5	hSpCas9	negative selection	10916844
129205261	129205284	7	+	28162770	PL21	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	1.7851021152104765	[13]	[20]	9	hSpCas9	negative selection	10916845
129205277	129205300	7	+	28162770	PL21	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-0.3539619225270755	[184]	[62]	-3	hSpCas9	negative selection	10916846
129206309	129206332	7	-	28162770	PL21	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	-1.6072153075682838	[76]	[10]	-8	hSpCas9	negative selection	10916847
129203448	129203471	7	+	28162770	P31FUJ	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	-0.20632999305318744	[53]	[54]	-2	hSpCas9	negative selection	11086207
129203400	129203423	7	-	28162770	P31FUJ	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	-0.8689900284907078	[128]	[82]	-6	hSpCas9	negative selection	11086208
129203422	129203445	7	-	28162770	P31FUJ	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	-0.0217785971571281	[272]	[315]	0	hSpCas9	negative selection	11086209
129205238	129205261	7	-	28162770	P31FUJ	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-1.4400082219361505	[440]	[190]	-7	hSpCas9	negative selection	11086210
129205261	129205284	7	+	28162770	P31FUJ	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	-0.8848789009940723	[21]	[13]	-6	hSpCas9	negative selection	11086211
129205277	129205300	7	+	28162770	P31FUJ	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-1.3452769336727914	[239]	[110]	-7	hSpCas9	negative selection	11086212
129206309	129206332	7	-	28162770	P31FUJ	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	-0.07526092742789864	[155]	[173]	0	hSpCas9	negative selection	11086213
129203448	129203471	7	+	28162770	OCIAML5	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	-1.189101558141568	[71]	[56]	-6	hSpCas9	negative selection	11255573
129203400	129203423	7	-	28162770	OCIAML5	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	1.1242173601621954	[45]	[180]	8	hSpCas9	negative selection	11255574
129203422	129203445	7	-	28162770	OCIAML5	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	-0.27807518796384395	[175]	[261]	-2	hSpCas9	negative selection	11255575
129205238	129205261	7	-	28162770	OCIAML5	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-1.671858596159824	[232]	[131]	-7	hSpCas9	negative selection	11255576
129205261	129205284	7	+	28162770	OCIAML5	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	-0.3532607138925554	[45]	[64]	-3	hSpCas9	negative selection	11255577
129205277	129205300	7	+	28162770	OCIAML5	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-0.1812262349824352	[124]	[198]	-1	hSpCas9	negative selection	11255578
129206309	129206332	7	-	28162770	OCIAML5	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	0.2952096916331152	[106]	[236]	2	hSpCas9	negative selection	11255579
129203448	129203471	7	+	28162770	EOL1	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	0.18758217740432825	[134]	[80]	1	hSpCas9	negative selection	11424939
129203400	129203423	7	-	28162770	EOL1	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	0.9992451388481354	[206]	[217]	8	hSpCas9	negative selection	11424940
129203422	129203445	7	-	28162770	EOL1	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	1.5169550844528552	[450]	[679]	9	hSpCas9	negative selection	11424941
129205238	129205261	7	-	28162770	EOL1	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-0.6555489739788055	[887]	[296]	-5	hSpCas9	negative selection	11424942
129205261	129205284	7	+	28162770	EOL1	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	-1.453963851683195	[25]	[4]	-7	hSpCas9	negative selection	11424943
129205277	129205300	7	+	28162770	EOL1	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-1.548623903693065	[210]	[37]	-7	hSpCas9	negative selection	11424944
129206309	129206332	7	-	28162770	EOL1	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	-0.12436182891041181	[119]	[57]	-1	hSpCas9	negative selection	11424945
129203448	129203471	7	+	28162770	MOLM13	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	-0.532110618455421	[97]	[48]	-3	hSpCas9	negative selection	11594305
129203400	129203423	7	-	28162770	MOLM13	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	0.7258705596520871	[142]	[170]	5	hSpCas9	negative selection	11594306
129203422	129203445	7	-	28162770	MOLM13	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	1.4662147498523248	[430]	[860]	9	hSpCas9	negative selection	11594307
129205238	129205261	7	-	28162770	MOLM13	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-2.832722482105691	[738]	[74]	-8	hSpCas9	negative selection	11594308
129205261	129205284	7	+	28162770	MOLM13	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	1.5971723984895454	[15]	[34]	9	hSpCas9	negative selection	11594309
129205277	129205300	7	+	28162770	MOLM13	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-1.6915888324626178	[343]	[76]	-7	hSpCas9	negative selection	11594310
129206309	129206332	7	-	28162770	MOLM13	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	0.9648271344685109	[106]	[150]	7	hSpCas9	negative selection	11594311
129203448	129203471	7	+	28162770	HEL	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	0.7546317120712542	[61]	[66]	6	hSpCas9	negative selection	11763671
129203400	129203423	7	-	28162770	HEL	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	1.545441630645442	[114]	[214]	9	hSpCas9	negative selection	11763672
129203422	129203445	7	-	28162770	HEL	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	-0.05427463676574096	[367]	[226]	0	hSpCas9	negative selection	11763673
129205238	129205261	7	-	28162770	HEL	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-0.9447658632832526	[567]	[188]	-5	hSpCas9	negative selection	11763674
129205261	129205284	7	+	28162770	HEL	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	0.505235308250422	[21]	[19]	4	hSpCas9	negative selection	11763675
129205277	129205300	7	+	28162770	HEL	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-1.7264949776653618	[247]	[47]	-7	hSpCas9	negative selection	11763676
129206309	129206332	7	-	28162770	HEL	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	-0.9309964132975451	[127]	[42]	-5	hSpCas9	negative selection	11763677
129203448	129203471	7	+	28162770	MV411	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	-1.717797031056548	[81]	[20]	-8	hSpCas9	negative selection	11933037
129203400	129203423	7	-	28162770	MV411	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	0.40940503044616827	[100]	[112]	3	hSpCas9	negative selection	11933038
129203422	129203445	7	-	28162770	MV411	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	0.49021311763276904	[250]	[296]	4	hSpCas9	negative selection	11933039
129205238	129205261	7	-	28162770	MV411	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-1.5646294986241496	[459]	[130]	-7	hSpCas9	negative selection	11933040
129205261	129205284	7	+	28162770	MV411	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	-1.7525624492172245	[15]	[3]	-8	hSpCas9	negative selection	11933041
129205277	129205300	7	+	28162770	MV411	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	0.5168274516563925	[150]	[181]	4	hSpCas9	negative selection	11933042
129206309	129206332	7	-	28162770	MV411	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	0.8947659324643051	[82]	[129]	7	hSpCas9	negative selection	11933043
129203448	129203471	7	+	28162770	MONOMAC1	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	-0.1970368470595536	[33]	[33]	-2	hSpCas9	negative selection	12102403
129203400	129203423	7	-	28162770	MONOMAC1	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	1.021972934882242	[60]	[141]	8	hSpCas9	negative selection	12102404
129203422	129203445	7	-	28162770	MONOMAC1	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	-0.2977308466790269	[177]	[165]	-3	hSpCas9	negative selection	12102405
129205238	129205261	7	-	28162770	MONOMAC1	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-1.2016832119159186	[310]	[154]	-7	hSpCas9	negative selection	12102406
129205261	129205284	7	+	28162770	MONOMAC1	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	0.18998627604969354	[12]	[16]	2	hSpCas9	negative selection	12102407
129205277	129205300	7	+	28162770	MONOMAC1	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-0.32136498206175534	[108]	[99]	-3	hSpCas9	negative selection	12102408
129206309	129206332	7	-	28162770	MONOMAC1	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	0.613138594060429	[72]	[127]	6	hSpCas9	negative selection	12102409
129203448	129203471	7	+	28162770	OCIAML2	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	-0.055592325963317535	[11]	[63]	0	hSpCas9	negative selection	12271769
129203400	129203423	7	-	28162770	OCIAML2	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	1.0654230749980487	[19]	[231]	8	hSpCas9	negative selection	12271770
129203422	129203445	7	-	28162770	OCIAML2	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	-0.19562277774229136	[49]	[241]	-2	hSpCas9	negative selection	12271771
129205238	129205261	7	-	28162770	OCIAML2	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-0.6197732645479704	[83]	[302]	-5	hSpCas9	negative selection	12271772
129205261	129205284	7	+	28162770	OCIAML2	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	-0.35515260782222535	[2]	[12]	-3	hSpCas9	negative selection	12271773
129205277	129205300	7	+	28162770	OCIAML2	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-1.051916667819919	[48]	[130]	-6	hSpCas9	negative selection	12271774
129206309	129206332	7	-	28162770	OCIAML2	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	0.67776201465051	[14]	[132]	6	hSpCas9	negative selection	12271775
129203448	129203471	7	+	28162770	OCIAML3	viability	CAAGTGTGAGAATGACCGGGTGG	SMO	ENSG00000128602	1.1812860725011425	[12]	[88]	8	hSpCas9	negative selection	12441135
129203400	129203423	7	-	28162770	OCIAML3	viability	GCTGGATCACTGCCCAGCAGCGG	SMO	ENSG00000128602	1.065501813762047	[21]	[138]	8	hSpCas9	negative selection	12441136
129203422	129203445	7	-	28162770	OCIAML3	viability	ATGTATACGGCACACAGCAGGGG	SMO	ENSG00000128602	0.12789050575310135	[76]	[253]	1	hSpCas9	negative selection	12441137
129205238	129205261	7	-	28162770	OCIAML3	viability	GAACCAAGGGCACTTCGCACTGG	SMO	ENSG00000128602	-0.8330536899663329	[166]	[282]	-6	hSpCas9	negative selection	12441138
129205261	129205284	7	+	28162770	OCIAML3	viability	GGACAGACAACCCCAAGAGCTGG	SMO	ENSG00000128602	-2.1789701410453195	[5]	[3]	-8	hSpCas9	negative selection	12441139
129205277	129205300	7	+	28162770	OCIAML3	viability	GAGCTGGTACGAGGACGTGGAGG	SMO	ENSG00000128602	-0.15512339909095177	[44]	[121]	-1	hSpCas9	negative selection	12441140
129206309	129206332	7	-	28162770	OCIAML3	viability	GGAGTGACCAGGTGAGCAGGTGG	SMO	ENSG00000128602	0.9689285540669941	[21]	[129]	8	hSpCas9	negative selection	12441141