Gene2Function

Disease Annotation

Gene Info

Species:Human (Homo sapiens)
GeneID:5728
Symbol:PTEN
Description:phosphatase and tensin homolog

Show high ranked Show all

Export (tab separated) Export to Excel

Disease_Term	Source	Rank	Other Values
Malignant melanoma, somatic, 155600 (3)	OMIM	high	Genome region :10q23.31 OMIM_ID :155600OMIM phenotype ID OMIM_ID :601728OMIM gene ID
{Meningioma}, 607174 (3)	OMIM	high	Genome region :10q23.31 OMIM_ID :601728OMIM gene ID OMIM_ID :607174OMIM phenotype ID
Squamous cell carcinoma, head and neck, somatic, 275355 (3)	OMIM	high	Genome region :10q23.31 Genome region :13q34 OMIM_ID :275355OMIM phenotype ID OMIM_ID :601566OMIM gene ID OMIM_ID :601728OMIM gene ID
Endometrial carcinoma, somatic, 608089 (3)	OMIM	high	Genome region :10q23.31 Genome region :16q22.1 Genome region :5q14.1 OMIM_ID :192090OMIM gene ID OMIM_ID :600887OMIM gene ID OMIM_ID :601728OMIM gene ID OMIM_ID :608089OMIM phenotype ID
{Prostate cancer, somatic}, 176807 (3)	OMIM	high	Genome region :10q23.31 OMIM_ID :176807OMIM phenotype ID OMIM_ID :601728OMIM gene ID
Lhermitte-Duclos syndrome, 158350 (3)	OMIM	high	Genome region :10q23.31 OMIM_ID :158350OMIM phenotype ID OMIM_ID :601728OMIM gene ID
Bannayan-Riley-Ruvalcaba syndrome, 153480 (3)	OMIM	high	Genome region :10q23.31 OMIM_ID :153480OMIM phenotype ID OMIM_ID :601728OMIM gene ID
VATER association with macrocephaly and ventriculomegaly, 276950 (3)	OMIM	high	Genome region :10q23.31 OMIM_ID :276950OMIM phenotype ID OMIM_ID :601728OMIM gene ID
Macrocephaly/autism syndrome, 605309 (3)	OMIM	high	Genome region :10q23.31 OMIM_ID :601728OMIM gene ID OMIM_ID :605309OMIM phenotype ID
{Glioma susceptibility 2}, 613028 (3)	OMIM	high	Genome region :10q23.31 OMIM_ID :601728OMIM gene ID OMIM_ID :613028OMIM phenotype ID
PTEN hamartoma tumor syndrome (3)	OMIM	high	Genome region :10q23.31 OMIM_ID :601728OMIM gene ID
Cowden syndrome 1, 158350 (3)	OMIM	high	Genome region :10q23.31 OMIM_ID :158350OMIM phenotype ID OMIM_ID :601728OMIM gene ID
Mercury levels	GWAS	high	Pubmed_ID : 26025379
Type 2 diabetes	GWAS	high	Pubmed_ID : 17293876 Pubmed_ID : 17460697 Pubmed_ID : 17463246 Pubmed_ID : 17463248 Pubmed_ID : 17463249 Pubmed_ID : 17554300 Pubmed_ID : 17668382 Pubmed_ID : 18372903 Pubmed_ID : 18711366 Pubmed_ID : 18711367 Pubmed_ID : 19056611 Pubmed_ID : 19401414 Pubmed_ID : 20174558 Pubmed_ID : 20418489 Pubmed_ID : 20581827 Pubmed_ID : 20818381 Pubmed_ID : 20862305 Pubmed_ID : 21347282 Pubmed_ID : 21490949 Pubmed_ID : 21573907 Pubmed_ID : 21647700 Pubmed_ID : 21799836 Pubmed_ID : 21874001 Pubmed_ID : 22101970 Pubmed_ID : 22158537 Pubmed_ID : 22238593 Pubmed_ID : 22293688 Pubmed_ID : 22456796 Pubmed_ID : 22693455 Pubmed_ID : 22961080 Pubmed_ID : 23209189 Pubmed_ID : 23300278 Pubmed_ID : 23532257 Pubmed_ID : 23937595 Pubmed_ID : 23945395 Pubmed_ID : 24101674 Pubmed_ID : 24390345 Pubmed_ID : 24509480 Pubmed_ID : 25102180 Pubmed_ID : 25483131 Pubmed_ID : 25760438 Pubmed_ID : 26818947 Pubmed_ID : 27189021
Periodontitis (Mean PAL)	GWAS	high	Pubmed_ID : 24024966