| GR00001-A | 33185 | FBgn0001309 | kis | DRSC00625 | -2.11 | none | | no | actin phenotype | Cell size regulation | PDGF/VEGF signaling controls cell size in Drosophila. | Sims et al. | 2009 | 19216764 | Cell line | S2R+ | F-actin and microtubule protein expression and DNA content | Fluorescence | rp | Genome-wide | dsRNA | Cell area Z-score | < -2 | | GR00002-A | 33185 | HDC00033 | | DRSC00521 | -1.0534308 | none | | no | | Lipid storage | COPI complex is a regulator of lipid homeostasis. | Beller et al. | 2008 | 19067489 | Cell line | Kc167 | Nuclear to lipid droplet cross-sectional area | Fluorescence | np | Genome-wide | dsRNA | B-score | > 2 OR < -1.7 | Additional information about a secondary screen with non-overlaping dsRNAs | GR00002-A | 33185 | HDC00033 | | DRSC00521 | 1.442182939 | none | | no | | Lipid storage | COPI complex is a regulator of lipid homeostasis. | Beller et al. | 2008 | 19067489 | Cell line | Kc167 | Nuclear to lipid droplet cross-sectional area | Fluorescence | np | Genome-wide | dsRNA | B-score | > 2 OR < -1.7 | Additional information about a secondary screen with non-overlaping dsRNAs | GR00002-A | 33185 | FBgn0001309 | kis | DRSC00625 | -1.198551996 | none | | no | | Lipid storage | COPI complex is a regulator of lipid homeostasis. | Beller et al. | 2008 | 19067489 | Cell line | Kc167 | Nuclear to lipid droplet cross-sectional area | Fluorescence | np | Genome-wide | dsRNA | B-score | > 2 OR < -1.7 | Additional information about a secondary screen with non-overlaping dsRNAs | GR00002-A | 33185 | FBgn0001309 | kis | DRSC00625 | 2.748781044 | none | | no | | Lipid storage | COPI complex is a regulator of lipid homeostasis. | Beller et al. | 2008 | 19067489 | Cell line | Kc167 | Nuclear to lipid droplet cross-sectional area | Fluorescence | np | Genome-wide | dsRNA | B-score | > 2 OR < -1.7 | Additional information about a secondary screen with non-overlaping dsRNAs | GR00002-A | 33185 | FBgn0001309 | kis | DRSC00823 | 1.850187423 | none | | no | | Lipid storage | COPI complex is a regulator of lipid homeostasis. | Beller et al. | 2008 | 19067489 | Cell line | Kc167 | Nuclear to lipid droplet cross-sectional area | Fluorescence | np | Genome-wide | dsRNA | B-score | > 2 OR < -1.7 | Additional information about a secondary screen with non-overlaping dsRNAs | GR00002-A | 33185 | FBgn0001309 | kis | DRSC00823 | 0.691917715 | none | | no | | Lipid storage | COPI complex is a regulator of lipid homeostasis. | Beller et al. | 2008 | 19067489 | Cell line | Kc167 | Nuclear to lipid droplet cross-sectional area | Fluorescence | np | Genome-wide | dsRNA | B-score | > 2 OR < -1.7 | Additional information about a secondary screen with non-overlaping dsRNAs | GR00021-A-0 | 33185 | FBgn0086902 | | DRSC00625 | moderate | ERK activation reduced | | no | | ERK signaling | A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling. | Friedman et al. | 2006 | 17086199 | Cell line | S2R+ | ERK signaling | Fluorescence | DRSC | | dsRNA | Weak, moderate, strong | np | | GR00031-A-1 | 33185 | | | HFA00625 | -1.6 | none | | yes | | Cell growth and viability (1) | Genome-wide RNAi analysis of growth and viability in Drosophila cells. | Boutros et al. | 2004 | 14764878 | Cell line | Kc167 | Cell number and viability | Luminescence | Custom-made (HFA) | Genome-wide | dsRNA | Z-score | > | | GR00031-A-1 | 33185 | | | HFA00521 | -1.3 | none | | yes | | Cell growth and viability (1) | Genome-wide RNAi analysis of growth and viability in Drosophila cells. | Boutros et al. | 2004 | 14764878 | Cell line | Kc167 | Cell number and viability | Luminescence | Custom-made (HFA) | Genome-wide | dsRNA | Z-score | > | | GR00031-A-1 | 33185 | | | HFA00823 | -0.1 | none | | yes | | Cell growth and viability (1) | Genome-wide RNAi analysis of growth and viability in Drosophila cells. | Boutros et al. | 2004 | 14764878 | Cell line | Kc167 | Cell number and viability | Luminescence | Custom-made (HFA) | Genome-wide | dsRNA | Z-score | > | | GR00031-A-2 | 33185 | | | HFA00823 | -0.3 | none | | no | | Cell growth and viability (2) | Genome-wide RNAi analysis of growth and viability in Drosophila cells. | Boutros et al. | 2004 | 14764878 | Cell line | S2R+ | Cell number and viability | Luminescence | Custom-made (HFA) | Genome-wide | dsRNA | Z-score | > | | GR00031-A-2 | 33185 | | | HFA00521 | -0.9 | none | | no | | Cell growth and viability (2) | Genome-wide RNAi analysis of growth and viability in Drosophila cells. | Boutros et al. | 2004 | 14764878 | Cell line | S2R+ | Cell number and viability | Luminescence | Custom-made (HFA) | Genome-wide | dsRNA | Z-score | > | | GR00031-A-2 | 33185 | | | HFA00625 | 0.4 | none | | no | | Cell growth and viability (2) | Genome-wide RNAi analysis of growth and viability in Drosophila cells. | Boutros et al. | 2004 | 14764878 | Cell line | S2R+ | Cell number and viability | Luminescence | Custom-made (HFA) | Genome-wide | dsRNA | Z-score | > | | GR00035-A | 33185 | CG3660 | CG3660 | KP003 | sp | none | | no | | Alternative splicing | Identification of alternative splicing regulators by RNA interference in Drosophila. | Park et al. | 2004 | 15492211 | Cell line | S2 | dAdar, para and Dscam mRNA expression | Reverse transcription PCR and autoradiography | Custom-made | RNA-binding protein genes and spliceosomal genes | dsRNA | np | Alternative exon splicing for > | | GR00043-A-0 | 33185 | FBgn0086902 | kis | np | np | Increased IMD reporter activity | | no | | Innate immunity | Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway. | Kleino et al. | 2005 | 16163390 | Cell line | S2 | IMD/Rel signaling | Dual luciferase | Custom-made | | dsRNA | Percentage IMD reporter activity | > | | | 33185 | FBgn0001309 | kis | GH25188 | sp | none | | no | library: DGC1 | | | | | | | | | | | | | | | | | 33185 | FBgn0001309 | kis | GM02209 | sp | none | | no | library: DGC1 | | | | | | | | | | | | | | | | | 33185 | FBgn0001309 | kis | LD09721 | sp | none | | no | library: DGC1 | | | | | | | | | | | | | | | | | 33185 | FBgn0001309 | kis | SD05649 | sp | none | | no | library: DGC1 | | | | | | | | | | | | | | | | GR00092-A | 33185 | FBgn0001309 | CG3696 | RDM1190-7303101 | np | none | | no | | Microtubule assembly and organization | Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin. | Ducat et al. | 2008 | 18463163 | Cell line | S2 | DNA content, alpha-tubulin and CP309 protein expression | Fluorescence | OpenBiosystems Drosophila RNAi Library 1.0 | Mitotic regulator genes | dsRNA | Complex, sp | Complex criteria | | GR00134-A-1 | 33185 | CG3696 | kis | 46685 | np | Lethal | | no | late pupal | Muscle morphogenesis and function (1) | Systematic genetic analysis of muscle morphogenesis and function in Drosophila. | Schnorrer et al. | 2010 | 20220848 | Tissue | Mef2-GAL4 | Posture, locomotion, flight and viability | Visual inspection | np | Genome-wide | UAS-IR construct | rp | S19 > 0.5 | | GR00134-A-1 | 33185 | CG3696 | kis | 10762 | np | none | | no | | Muscle morphogenesis and function (1) | Systematic genetic analysis of muscle morphogenesis and function in Drosophila. | Schnorrer et al. | 2010 | 20220848 | Tissue | Mef2-GAL4 | Posture, locomotion, flight and viability | Visual inspection | np | Genome-wide | UAS-IR construct | rp | S19 > 0.5 | | GR00135-A-1 | 33185 | CG3696 | kis | 10762 | -1.17 | none | | yes | | Heat nociception (1) | A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. | Neely et al. | 2010 | 21074052 | Organism | elav-GAL4 | Noxious heat avoidance and viability | Fly count | np | Genome-wide | UAS-IR construct | Z-score | > 1.65 | Additional information about secondary screens (geotactic, phototaxis, and temperature sensitivity) | GR00135-A-1 | 33185 | CG3696 | kis | 46685 | -0.02 | none | | yes | | Heat nociception (1) | A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. | Neely et al. | 2010 | 21074052 | Organism | elav-GAL4 | Noxious heat avoidance and viability | Fly count | np | Genome-wide | UAS-IR construct | Z-score | > 1.65 | Additional information about secondary screens (geotactic, phototaxis, and temperature sensitivity) | GR00138-A-1 | 33185 | CG3696 | | 46685 | 0.79 | none | | no | | Heart development and function (1) | A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. | Neely et al. | 2010 | 20371351 | Tissue | TinCΔ4 12a-Gal4 | Viability | Fly count | np | Selected genes | UAS-IR construct | Developmental lethality | < | | GR00138-A-1 | 33185 | CG3696 | | 10762 | 1 | none | | no | | Heart development and function (1) | A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. | Neely et al. | 2010 | 20371351 | Tissue | TinCΔ4 12a-Gal4 | Viability | Fly count | np | Selected genes | UAS-IR construct | Developmental lethality | < | | GR00142-A-1 | 33185 | CG3696 | CG3696 | 10762 | -0.654545454545454 | none | | no | | Serratia marcescens infection (1) | Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection. | Cronin et al. | 2009 | 19520911 | Organism | HSP70-GAL4; TubGAL80ts | Heat shock and viability | Fly count | np | Random genes | UAS-IR construct | Days life time (LT50) | < -1.5 SD OR > 2 SD | | GR00142-A-1 | 33185 | CG3696 | CG3696 | 10762 | 0.74025974025974 | none | | no | | Serratia marcescens infection (1) | Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection. | Cronin et al. | 2009 | 19520911 | Organism | HSP70-GAL4; TubGAL80ts | Heat shock and viability | Fly count | np | Random genes | UAS-IR construct | Days life time (LT50) | < -1.5 SD OR > 2 SD | | GR00142-A-1 | 33185 | CG3696 | CG3696 | 46685 | 0.104166666666666 | none | | no | | Serratia marcescens infection (1) | Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection. | Cronin et al. | 2009 | 19520911 | Organism | HSP70-GAL4; TubGAL80ts | Heat shock and viability | Fly count | np | Random genes | UAS-IR construct | Days life time (LT50) | < -1.5 SD OR > 2 SD | | GR00144-A-4 | 33185 | CG3696 | | 10762 | sp | Bristle morphology defects, planar polarity defects | | no | not lethal | Notch pathway regulation (4) | Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. | Mummery-Widmer et al. | 2009 | 19363474 | Tissue | pnr-GAL4 | External sensory organ morphology and viability | Visual inspection | np | Genome-wide | UAS-IR construct | Phenotype strength | np | | GR00144-A-4 | 33185 | CG3696 | | 46685 | sp | Loss of bristles, bristle morphology defects, notum malformation death | | no | not lethal | Notch pathway regulation (4) | Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. | Mummery-Widmer et al. | 2009 | 19363474 | Tissue | pnr-GAL4 | External sensory organ morphology and viability | Visual inspection | np | Genome-wide | UAS-IR construct | Phenotype strength | np | | GR00185-A | 33185 | CG3696 | Kismet | np | 95 | none | | no | 20 min heat shock | Pol II elongation | Spt6 enhances the elongation rate of RNA polymerase II in vivo. | Ardehali et al. | 2009 | 19279664 | Cell line | S2 | Hsp70 mRNA expression | Real-time qPCR | Custom-made | Transcription factors | dsRNA | Percentage | < | | GR00189-A-1 | 33185 | FBgn0086902 | kis | BKN20986 | np | Downregulation of Notch pathway | | yes | | Notch pathway regulation (1) | A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network. | Saj et al. | 2010 | 20493818 | Cell line | S2 | Notch pathway reporter | Luminescence | BKN | Genome-wide | dsRNA | Complex, sp | Complex criteria | | GR00189-A-2 | 33185 | FBgn0086902 | kis | 3696R-2 | very strong | Lethal | | yes | en-GAL4; final gene scoring: up- and downregulation of Notch pathway | Notch pathway regulation (2) | A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network. | Saj et al. | 2010 | 20493818 | Tissue | en-GAL4, C96-GAL4 and vg-GAL4 | Notch pathway reporter, wing imaginal discs morphology, adult wing morphology and viability | Fluorescence and visual inspection | Notch pathway component enriched RNAi library | Selected genes | UAS-IR construct | Phenotype strength | np | | GR00189-A-2 | 33185 | FBgn0086902 | kis | 3696R-2 | sp | Downregulation of Notch pathway; adult wing margin: notches | | yes | C96-GAL4; final gene scoring: up- and downregulation of Notch pathway | Notch pathway regulation (2) | A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network. | Saj et al. | 2010 | 20493818 | Tissue | en-GAL4, C96-GAL4 and vg-GAL4 | Notch pathway reporter, wing imaginal discs morphology, adult wing morphology and viability | Fluorescence and visual inspection | Notch pathway component enriched RNAi library | Selected genes | UAS-IR construct | Phenotype strength | np | | GR00189-A-2 | 33185 | FBgn0086902 | kis | 3696R-2 | sp | Up- and downregulation of Notch pathway; wing disc NRE:EGFP: up, gap; wing disc myrRFP: reduced | | yes | en-GAL4 | Notch pathway regulation (2) | A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network. | Saj et al. | 2010 | 20493818 | Tissue | en-GAL4, C96-GAL4 and vg-GAL4 | Notch pathway reporter, wing imaginal discs morphology, adult wing morphology and viability | Fluorescence and visual inspection | Notch pathway component enriched RNAi library | Selected genes | UAS-IR construct | Phenotype strength | np | | GR00189-A-2 | 33185 | FBgn0086902 | kis | 3696R-1 | sp | Upregulation of Notch pathway; adult wing veins: disrupted, thinner; adult wing posterior compartment: crumbled, opaque | | yes | en-GAL4; final gene scoring: up- and downregulation of Notch pathway | Notch pathway regulation (2) | A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network. | Saj et al. | 2010 | 20493818 | Tissue | en-GAL4, C96-GAL4 and vg-GAL4 | Notch pathway reporter, wing imaginal discs morphology, adult wing morphology and viability | Fluorescence and visual inspection | Notch pathway component enriched RNAi library | Selected genes | UAS-IR construct | Phenotype strength | np | | GR00189-A-3 | 33185 | FBgn0086902 | kis | np | np | Upregulation of Notch pathway | | no | | Notch pathway regulation (3) | A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network. | Saj et al. | 2010 | 20493818 | Tissue | GMR-GAL4 | Notch pathway reporter | Fluorescence | Notch pathway component enriched RNAi library | Selected genes | UAS-IR construct | Average fluorescent intensity | Complex criteria | | GR00190-A-1 | 33185 | FBgn0086902 | kis | 10762 | -0.48 | Decreased triglyceride expression | | yes | | Adiposity regulation (1) | Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. | Pospisilik et al. | 2010 | 20074523 | Organism | Hsp70-GAL4;Tub-GAL80ts | Total fly triglyceride expression | Colorimetrics | np | Genome-wide | UAS-IR construct | Triglyceride change | Z-score > 1.65 after 3 screening rounds | Additional information about the primary screen | GR00190-A-1 | 33185 | FBgn0086902 | kis | 46685 | 0.644 | none | | yes | | Adiposity regulation (1) | Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. | Pospisilik et al. | 2010 | 20074523 | Organism | Hsp70-GAL4;Tub-GAL80ts | Total fly triglyceride expression | Colorimetrics | np | Genome-wide | UAS-IR construct | Triglyceride change | Z-score > 1.65 after 3 screening rounds | Additional information about the primary screen | GR00190-A-1 | 33185 | FBgn0086902 | kis | 10762 | -0.634 | Decreased triglyceride expression | | yes | | Adiposity regulation (1) | Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. | Pospisilik et al. | 2010 | 20074523 | Organism | Hsp70-GAL4;Tub-GAL80ts | Total fly triglyceride expression | Colorimetrics | np | Genome-wide | UAS-IR construct | Triglyceride change | Z-score > 1.65 after 3 screening rounds | Additional information about the primary screen | GR00190-A-2 | 33185 | FBgn0086902 | kis | 46685 | -0.219 | none | | no | | Adiposity regulation (2) | Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. | Pospisilik et al. | 2010 | 20074523 | Tissue | nsyb-GAL4 | Total fly triglyceride expression | Colorimetrics | np | Selected genes | UAS-IR construct | Triglyceride change | > 0.25 OR <-0.25 (change >25%) | Additional information about the primary screen | GR00190-A-3 | 33185 | FBgn0086902 | kis | 46685 | 0.081 | none | | no | | Adiposity regulation (3) | Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. | Pospisilik et al. | 2010 | 20074523 | Tissue | C57-GAL4 | Total fly triglyceride expression | Colorimetrics | np | Selected genes | UAS-IR construct | Triglyceride change | > 0.25 OR <-0.25 (change >25%) | Additional information about the primary screen | GR00190-A-4 | 33185 | FBgn0086902 | kis | 46685 | 0.272 | Increased triglyceride expression | | no | | Adiposity regulation (4) | Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. | Pospisilik et al. | 2010 | 20074523 | Tissue | oe-GAL4 | Total fly triglyceride expression | Colorimetrics | np | Selected genes | UAS-IR construct | Triglyceride change | > 0.25 OR <-0.25 (change >25%) | Additional information about the primary screen | GR00190-A-5 | 33185 | FBgn0086902 | kis | 46685 | -0.089 | none | | no | | Adiposity regulation (5) | Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. | Pospisilik et al. | 2010 | 20074523 | Tissue | ppl-GAL4 | Total fly triglyceride expression | Colorimetrics | np | Selected genes | UAS-IR construct | Triglyceride change | > 0.25 OR <-0.25 (change >25%) | Additional information about the primary screen | GR00214-A-1 | 33185 | FBgn0086902 | kis | DRSC00625 | 0.71 | none | 0 minutes EGF stimulation | yes | | RTK-Ras-ERK pathway regulation (1) | Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling. | Friedman et al. | 2011 | 22028469 | Cell line | S2R+ | ERK phosphorylation | Fluorescence | np | Genome-wide | dsRNA | Z-score | > 1.5 OR < -1.5 | | GR00214-A-1 | 33185 | FBgn0086902 | kis | DRSC00625 | 0.46 | none | 10 minutes EGF stimulation | yes | | RTK-Ras-ERK pathway regulation (1) | Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling. | Friedman et al. | 2011 | 22028469 | Cell line | S2R+ | ERK phosphorylation | Fluorescence | np | Genome-wide | dsRNA | Z-score | > 1.5 OR < -1.5 | | GR00214-A-2 | 33185 | FBgn0086902 | kis | DRSC00625 | 0.32 | none | 10 minutes sSpitz stimulation | no | | RTK-Ras-ERK pathway regulation (2) | Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling. | Friedman et al. | 2011 | 22028469 | Cell line | Kc167 | ERK phosphorylation | Fluorescence | np | Genome-wide | dsRNA | Z-score | > 1.5 OR < -1.5 | | GR00214-A-2 | 33185 | FBgn0086902 | kis | DRSC00625 | 2.56 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 30 minutes sSpitz stimulation | yes | | RTK-Ras-ERK pathway regulation (2) | Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling. | Friedman et al. | 2011 | 22028469 | Cell line | Kc167 | ERK phosphorylation | Fluorescence | np | Genome-wide | dsRNA | Z-score | > 1.5 OR < -1.5 | | GR00239-A-1 | 33185 | CG3696 | | 3696R | sp | none | | no | | Glycosylation regulation (1) | Identification of genes required for neural-specific glycosylation using functional genomics. | Yamamoto-Hino et al. | 2010 | 21203496 | Tissue | GMR-GAL4 | Chaoptin (Chp) protein expression, alpha1,3-fucose, alpha1,6-fucose, (GlcNAc)n, GlcNAcb1-4GlcNAc and mannose Chp glycosylation and viability | Luminescence | np | Selected genes | UAS-IR construct | Z-score | > 3 | | GR00239-A-1 | 33185 | CG18326 | | 18326R | sp | none | | no | | Glycosylation regulation (1) | Identification of genes required for neural-specific glycosylation using functional genomics. | Yamamoto-Hino et al. | 2010 | 21203496 | Tissue | GMR-GAL4 | Chaoptin (Chp) protein expression, alpha1,3-fucose, alpha1,6-fucose, (GlcNAc)n, GlcNAcb1-4GlcNAc and mannose Chp glycosylation and viability | Luminescence | np | Selected genes | UAS-IR construct | Z-score | > 3 | | GR00282-A | 33185 | CG3696 | kis | 10762 | np | none | | | | piRNA pathway regulation | The Genetic Makeup of the Drosophila piRNA Pathway | Handler | 2013 | 23665231 | Tissue | tj-GAL4 | Gypsy transposon expression | Microscopy | VDRC | Selected genes | UAS-IR construct | Visual inspection | np | See comment for ovarian morphology data. Gene expression data shown in the comment derive from an ovarian stem cell line. VDRC library: KK and GD used, see phenotype data | GR00282-A | 33185 | CG3696 | kis | 46685 | np | none | | | | piRNA pathway regulation | The Genetic Makeup of the Drosophila piRNA Pathway | Handler | 2013 | 23665231 | Tissue | tj-GAL4 | Gypsy transposon expression | Microscopy | VDRC | Selected genes | UAS-IR construct | Visual inspection | np | See comment for ovarian morphology data. Gene expression data shown in the comment derive from an ovarian stem cell line. VDRC library: KK and GD used, see phenotype data | GR00284-A | 33185 | CG3696 | kis | 109414 | 0.15822399381844954 | none | | | | piRNA pathway regulation | A Transcriptome-wide RNAi Screen in the Drosophila Ovary Reveals Factors of the Germline piRNA Pathway | Czech et al. | 2013 | 23665227 | Tissue | nos-GAL4 | Transposon expression | qPCR | VDRC | Selected genes | UAS-IR construct | Z-score | Weak < -1.5; strong: < -2 | KK and GD libraries used (see phenotype data) | GR00311-A | 33185 | FBgn0086902 | kis | DRSC00625 | np | none | | | | Actin and microtubule morphology | Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype | Rohn et al. | 2011 | 21893601 | Cell line | S2R+ | Alpha-tubulin and F-actin protein expression | Fluorescence | DRSC | Genome-wide | dsRNA | Visual inspection | np | Exact phenotypes are shown in the comment section. Several genes were indicated as hits but no phenotype was provided. The screen data plus images is available at http://jcb-dataviewer.rupress.org/jcb/browse/4609/S2. | GR00311-A | 33185 | FBgn0086902 | kis | DRSC00823 | np | none | | | | Actin and microtubule morphology | Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype | Rohn et al. | 2011 | 21893601 | Cell line | S2R+ | Alpha-tubulin and F-actin protein expression | Fluorescence | DRSC | Genome-wide | dsRNA | Visual inspection | np | Exact phenotypes are shown in the comment section. Several genes were indicated as hits but no phenotype was provided. The screen data plus images is available at http://jcb-dataviewer.rupress.org/jcb/browse/4609/S2. | GR00311-A | 33185 | FBgn0086902 | kis | DRSC00521 | np | none | | | | Actin and microtubule morphology | Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype | Rohn et al. | 2011 | 21893601 | Cell line | S2R+ | Alpha-tubulin and F-actin protein expression | Fluorescence | DRSC | Genome-wide | dsRNA | Visual inspection | np | Exact phenotypes are shown in the comment section. Several genes were indicated as hits but no phenotype was provided. The screen data plus images is available at http://jcb-dataviewer.rupress.org/jcb/browse/4609/S2. | GR00315-A-1 | 33185 | CG3696 | kis | 109414 | np | none | | | | Follicular epithelium development (1) | A genome-scale in vivo RNAi analysis of epithelial development in Drosophila identifies new proliferation domains outside of the stem cell niche | Berns et al. | 2014 | 24762813 | Tissue | Escargot-GAL4 and GR1-GAL4, GR1-GAL4, traffic jam-GAL4 | Follicular epithelium morphology | Fluorescence | VDRC KK | Random genes | UAS-IR construct | Visual inspection | np | Further classification screen available, see follicular epithelium development (2). | GR00335-A | 33185 | FBgn0086902 | kis | GL00557 | np | Oogenesis defect | | | | Germline stem cell (GSC) regulation | A Regulatory Network of Drosophila Germline Stem Cell Self-Renewal | Yan et al. | 2014 | 24576427 | Tissue | MTD-GAL4 or UAS-dcr2; nanos-GAL4 | Spectrin and vasa protein expression | Fluorescence | TRiP | Selected genes | UAS-IR construct | Visual inspection | np | More detailed phenotypes for some genes are shown in the comment. Various VALIUM vectors were used. | | 33185 | FBgn0086902 | np | np | sp | none | | | | | | | | | | | | | | | | | | | GR00367-S | 33185 | CG3696 | | 46685 | np | lethal or adult morphology phenotype | | | VDRC | Drosophila airway maturation | Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes | Hosono et al. | 2015 | 26551273 | Tissue | btl-GAL4 | Liquid clearance defect and viability | Visual inspection | VDRC, Trip, NIG | Genome-wide | UAS-IR construct | Frequency | >30% | | GR00379-A-1 | 33185 | CG3696 | | 109414 | -0.45282614196640814 | none | | | No phenotype in egg laying/hatching or larvae in egg laying or larvae | Stem cell maintenance | Regulation of Ribosome Biogenesis and Protein Synthesis Controls Germline Stem Cell Differentiation | Sanchez et al. | 2016 | 26669894 | Organism | nanos-GAL4 | nos and yTub37c mRNA expression | qPCR | VDRC | Selected genes | UAS-IR construct | Z-score | Low: 1 - 2.5; Medium: 2.5 - 4; High: > | Selected genes are: transcriptome-wide in female Drosophila. Additional phenotypes (egg laying/hatching) noted in the comment section. Subset libraries from VDRC (KK or GD) can be found in a column next to the comment field. | GR00388-A | 33185 | CG3696 | | GD46685 | | Lethal | | | | Regulation of intestinal stem cells (ISC) | Genome-wide RNAi Screen Identifies Networks Involved in Intestinal Stem Cell Regulation in Drosophila | Zeng et al. | 2015 | 25704823 | Tissue | act5C-GAL4 | Viability | Visual inspection | VDRC and BDSC | Genome-wide | UAS-IR construct | np | np | Lethal transgenic lines identified from the primary screen were crossed with temperature-sensitive esg-GAL4 flies. Phenotypes of ISCs from the dissected midguts are shown in the "Comment" section. | GR00388-A | 33185 | CG3696 | | BL34908 | | Lethal | | | | Regulation of intestinal stem cells (ISC) | Genome-wide RNAi Screen Identifies Networks Involved in Intestinal Stem Cell Regulation in Drosophila | Zeng et al. | 2015 | 25704823 | Tissue | act5C-GAL4 | Viability | Visual inspection | VDRC and BDSC | Genome-wide | UAS-IR construct | np | np | Lethal transgenic lines identified from the primary screen were crossed with temperature-sensitive esg-GAL4 flies. Phenotypes of ISCs from the dissected midguts are shown in the "Comment" section. |