Gene2Function

RNAi

Gene Info

Species:Human (Homo sapiens)
GeneID:54798
Symbol:DCHS2
Description:dachsous cadherin-related 2

DataSource: http://genomernai.dkfz.de/v16/genedetails/54798

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Stable_ID	Entrez_ID	Gene_ID	Gene_Symbol	Reagent_ID	Score	Phenotype	Follow_Up	Comment	Screen_Title	Publication_Title	Authors	Publication_Year	Pubmed_ID	Biosource	Biomodel	Assay	Method	Library	Scope	Reagent_Type	Score_Type	Cutoff	Notes
GR00053-A	54798	NM_017639	CDHJ	np	sp	none	no		Genome stability	A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability.	Paulsen et al.	2009	19647519	Cell line	HeLa	gamma-H2AX phosphorylation and DNA content	Fluorescence	siARRAY human genome siRNA library	Genome-wide	siRNA	p-value	Complex criteria	Confidence groupings from 4 to 1 (highest level of confidence in group 4)
GR00054-A	54798	NM_017639	CDHJ	np	0.813	none	no		Combinatorial effect with paclitaxel	Synthetic lethal screen identification of chemosensitizer loci in cancer cells.	Whitehurst et al.	2007	17429401	Cell line	NCI-H1155	Viability (synthetic lethal)	ATP level	# G-005000-01	Genome-wide	siRNA	Paclitaxel/control ratio	Complex criteria	Additional information about 87 high-confidence hits
GR00056-A	54798	NM_017639	CDHJ	np	0.812	none	no		Melanogenesis	Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells.	Ganesan et al.	2008	19057677	Cell line	MNT-1	Melanin protein expression and viability	Absorbance and luminescence	rp	Genome-wide	siRNA	Normalized absorbance ratio	> 2 standard deviations below mean	Additional information about a secondary screen (retest to determine false-positive rate)
GR00057-A-1	54798	NM_017639	CDHJ	M-020602-00	-0.53	none	no		Wnt/beta-catenin pathway regulation (1)	A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer.	Tang et al.	2008	18621708	Cell line	HeLa	Wnt pathway reporter	Luminescence	Human siArray siRNA library	Genome-wide	siRNA	Z-score	> 4	Screen without Wnt3A stimulation. Additional information about secondary screens (Dharmacon and Qiagen libraries).
GR00057-A-2	54798	NM_017639	CDHJ	M-020602-00	sp	none	no		Wnt/beta-catenin pathway regulation (2)	A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer.	Tang et al.	2008	18621708	Cell line	HeLa	Wnt pathway reporter	Luminescence	Human siArray siRNA library	Genome-wide	siRNA	Complex, SP	Complex criteria	Screen with Wnt3A stimulation. Additional information about secondary screens (Dharmacon and Qiagen libraries).
GR00098-A-1	54798	ENSG00000197410	DCHS2	ENSG00000197410	sp	none	no		Cell division (1)	Genome-scale RNAi profiling of cell division in human tissue culture cells.	Kittler et al.	2007	17994010	Cell line	HeLa	Cell number and DNA content	Laser scanning cytometry	rp	Genome-wide	esiRNA	Complex, sp	Complex criteria
GR00133-A-1	54798	54798	DCHS2	np	-0.065946	none	no		Salmonella enterica subspecies 1 serovar Typhimurium invasion (1)	RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42.	Misselwitz et al.	2011	21407211	Cell line	HeLa	Gentamycin protection invasion assay	Fluorescence	Druggable genome library V2.0	Druggable genes	siRNA	log2 median	Complex criteria
GR00151-A-1	54798	ENSG00000197410	DCHS2	np	-0.381	none	no		Homologous recombination DNA double-strand break repair (HR-DSBR) (1)	A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia.	Słabicki et al.	2010	20613862	Cell line	HeLa	(HR-DSBR) DR-GFP reporter	Flow cytometry	Custom-made	Genome-wide	esiRNA	Z-score	< -2 OR > 2
GR00180-A-1	54798	54798	DCHS2	PL-50059	0.909	none	no		Hepatitis C virus replication (1)	A functional genomic screen identifies cellular cofactors of hepatitis C virus replication.	Tai et al.	2009	19286138	Cell line	Huh7/Rep-Feo	HCV replicon RNA copy number	Luminescence	siARRAY Human Genome siRNA Library	Genome-wide	siRNA	q-value	Complex criteria
GR00184-A-1	54798	NM_017639	DCHS2	M-020602-00	-1.0272767697495	none	no		Self-renewal and pluripotency in human embryonic stem cells (1)	A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity.	Chia et al.	2010	20953172	Cell line	hESC H1	POU5F1 protein expression	Fluorescence	SMARTpool siRNA library	Genome-wide	siRNA	Z-score	< -2
GR00197-A-1	54798	54798	DCHS2	M-020602-00	-0.575030073	none	no		Human papillomavirus oncogene expression regulation (1)	Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression.	Smith et al.	2010	20133580	Cell line	C33A/BE2/18LCR c4	HPV18 LCR reporter activity	Luminescence	Human siGENOME SMARTpool library	Genome-wide	siRNA	Z-score	>	Author-submitted data. Phenotype strength according to Z-scores: weak: 2 - 3; moderate: 3 - 5; strong: > 5
GR00236-A-1	54798	54798	DCHS2	M-020602-00	1.18520810160421	none	no		Homologous recombination DNA double-strand break repair (HR-DSBR) (1)	A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response.	Adamson et al.	2012	22344029	Cell line	DR-U2OS	(HR-DSBR) DR-GFP reporter and DNA content	Fluorescence	Human siGENOME siRNA (G-005000-05)	Genome-wide	siRNA	Relative HR ratio	< ~0.4 OR > 1.88	Cutoff values correspond 2 standard deviations from the screen-wide mean
GR00240-S-1	54798	NM_017639	CDHJ	M-020602-00	-0.98	none	yes		TRAIL-induced apoptosis (1)	A synthetic lethal screen identifies FAT1 as an antagonist of caspase-8 in extrinsic apoptosis.	Kranz and Boutros	2014	24442637	Cell line	U251MG	Viability	Luminescence	SMART-pool siRNA	Genome-wide	siRNA	Z-score	> 4	Author-submitted data
GR00240-S-2	54798	NM_017639	CDHJ	M-020602-00	-0.23	none	no	Z-score -0.967	TRAIL-induced apoptosis (2)	A synthetic lethal screen identifies FAT1 as an antagonist of caspase-8 in extrinsic apoptosis.	Kranz and Boutros	2014	24442637	Cell line	U251MG	Viability (synthetic lethal)	Luminescence	SMART-pool siRNA	Genome-wide	siRNA	Differential score	> 3.6 AND viability Z-score < 4	Author-submitted data. Z-scores from viability screen (1) are considered in score interpretation for this screen.
GR00242-A-1	54798	NM_017639	CDHJ	np	sp	none	no		Selective autophagy regulation (1)	Image-based genome-wide siRNA screen identifies selective autophagy factors.	Orvedahl et al.	2011	22020285	Cell line	HeLa/GFP-LC3	Sindbis virus (SIN) capsid SIN-mCherry.capsid and autophagosome GFP–LC3 protein expression	Fluorescence	siGenome	Genome-wide	siRNA	Z-score	Complex criteria
GR00247-A-1	54798		DCHS2	np	sp	none		rank: 14158	Regulation of FOXO1 nuclear localization (1)	Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain.	Senapedis et al.	2011	21460183	Cell line	U2OS	EGFP-FOXO1a protein expression and DNA content	Fluorescence	Human Genome library	Genome-wide	siRNA	Complex, sp	Complex criteria
GR00249-S	54798	54798	DCHS2	s29456	-0.17558	none	no	number of cells compared to control (%): 90.43	Vaccinia virus (VACV) infection	Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis.	Sivan et al.	2013	23401514	Cell line	HeLa	Vaccinia virus VACV IHD-J/GFP protein expression and DNA content	Fluorescence	Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus	Genome-wide	siRNA	Z-score	>	Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %.
GR00249-S	54798	54798	DCHS2	s29457	0.16793	none	no	number of cells compared to control (%): 84.24	Vaccinia virus (VACV) infection	Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis.	Sivan et al.	2013	23401514	Cell line	HeLa	Vaccinia virus VACV IHD-J/GFP protein expression and DNA content	Fluorescence	Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus	Genome-wide	siRNA	Z-score	>	Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %.
GR00249-S	54798	54798	DCHS2	s29458	-1.44319	none	no	number of cells compared to control (%): 68.28	Vaccinia virus (VACV) infection	Human genome-wide RNAi screen reveals a role for nuclear pore proteins in poxvirus morphogenesis.	Sivan et al.	2013	23401514	Cell line	HeLa	Vaccinia virus VACV IHD-J/GFP protein expression and DNA content	Fluorescence	Silencer Select Version 4, siGENOME SMARTpool and OnTargetPlus	Genome-wide	siRNA	Z-score	>	Author-submitted data. Primary screen. Decreased viability phenotype if number of cells compared to control < 50 %.
GR00253-A	54798	NM_017639	CDHJ	np	0.787	none			hepcidin regulation	Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling.	Mleczko-Sanecka et al.	2014	24385536	Cell line	Huh7	hepcidin::fluc mRNA expression	Luminescence	siGenome siARRAY SMARTpool	Genome-wide	siRNA	Z-score	>	Cutoff <
GR00255-A-1	54798	54798	DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055678, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.208883517	none			Negative genetic interactions (1)	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	Vizeacoumar et al.	2013	24104479	Cell line	HCT116	shRNA abundance	Microarray	np	Genome-wide	shRNA	differential Gene Activity Ranking Profile (dGARP)	< -1.0	HCT116 BLM-/- and HCT116 BLM+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells)
GR00255-A-2	54798	54798	DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055678, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.411149435	none			Negative genetic interactions (2)	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	Vizeacoumar et al.	2013	24104479	Cell line	HCT116	shRNA abundance	Microarray	np	Genome-wide	shRNA	differential Gene Activity Ranking Profile (dGARP)	< -1.0	HCT116 MUS81-/- and HCT116 MUS81+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells)
GR00255-A-3	54798	54798	DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055678, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.184325094	none			Negative genetic interactions (3)	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	Vizeacoumar et al.	2013	24104479	Cell line	HCT116	shRNA abundance	Microarray	np	Genome-wide	shRNA	differential Gene Activity Ranking Profile (dGARP)	< -1.2	HCT116 PTEN-/- and HCT116 PTEN+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells)
GR00255-A-4	54798	54798	DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055678, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.952981829	none			Negative genetic interactions (4)	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	Vizeacoumar et al.	2013	24104479	Cell line	HCT116	shRNA abundance	Microarray	np	Genome-wide	shRNA	differential Gene Activity Ranking Profile (dGARP)	< -1.2	HCT116 PTTG1-/- and HCT116 PTTG1+/+ cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells)
GR00255-A-5	54798	54798	DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055678, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.655730133	none			Negative genetic interactions (5)	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	Vizeacoumar et al.	2013	24104479	Cell line	HCT116	shRNA abundance	Microarray	np	Genome-wide	shRNA	differential Gene Activity Ranking Profile (dGARP)	< -0.8	HCT116 KRASG13D/- and HCT116 KRAS+/- cells used. Cutoff corresponds to p-value < 0.05. Additional information about a secondary screen (genetic interactions with Cetuximab/Erbitux in LIM1215 cells)
GR00257-A-1	54798		dchs2	147650	sp	Decreased viability (cell death)			Cell division, migration and survival (1)	Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes.	Neumann et al.	2010	20360735	Cell line	HeLa	H2B-GFP protein expression	Fluorescence	Mapped using ENSEMBL genome database version 27	Selected genes	siRNA	Complex, sp	Complex criteria	HeLa-H2B-GFP cells used.
GR00293-A	54798		CDHJ	np	1.005	none			Combinatorial effect with paclitaxel	Mechanisms Promoting Escape from Mitotic Stress−Induced Tumor Cell Death	Sinnott et al.	2014	24860162	Cell line	HCC366	Viability	Luminescence	Thermo-Fisher	Genome-wide	siRNA	Z-score	< -2.5	Final hits according to the author are indicated in the comment.
GR00300-A	54798		DCHS2	TRCN0000055681, TRCN0000055682, TRCN0000055633, TRCN0000055678, TRCN0000055679, TRCN0000055634, TRCN0000055637, TRCN0000055680, TRCN0000055636	0	none			Combinatorial effect with RAF inhibitor PLX4720	A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition.	Whittaker et al.	2013	23288408	Cell line	A375	shRNA abundance	Sequencing	TRC	Genome-wide	shRNA	Number of shRNAs ranked Top1000	> 2	The A375 cell line used here harbours the BRAF V600E mutation and is therefore sensitive to RAF inhibitors.
GR00303-A	54798	NM_017639	CDHJ	np	-0.12	none			Clear cell renal cell carcinoma (ccRCC) survival regulation	Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target	Gerlinger et al.	2012	22362593	Cell line	VHL-deficient RCC4	Proliferation and Viability	Fluorescence	np	Genome-wide	siRNA	Z-score	<	In the phenotype data duplicates were in the original document, which have been removed.
GR00310-A-1	54798	54798	DCHS2	np	0.09	none			Sindbis virus (SINV) infection (1)	Genome-Wide RNAi Screen Identifies Novel Host Proteins Required for Alphavirus Entry	Ooi et al.	2013	24367265	Cell line	U2OS	Sindbis virus (SINV) reporter	Luminescence	Ambion Silencer V3	Genome-wide	siRNA	Z-score	< -3 OR > 2
GR00313-A	54798	NM_017639, NM_199348	DCHS2	np	0.46	none			TNF-alpha pathway regulation	A Genome-Wide RNA Interference Screen Identifies Caspase 4 as a Factor Required for Tumor Necrosis Factor Alpha Signaling.	Nickles et al.	2012	22733992	Cell line	HEK293T	NFkappaB pathway reporter	Luminescence	Qiagen	Genome-wide	siRNA	Z-score	<	Additional filters were a reduction in firefly luciferase levels by at least 50% compared to the mean of the experiment and a concomitant reduction of renilla luciferase expression of not more than 30%.
GR00366-A-1	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.906103686954556	none		DCHS2_1_111111111	Context-specific genetic dependencies (1)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	22RV1_PROSTATE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-10	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.28469150823113	none		DCHS2_1_111111111	Context-specific genetic dependencies (10)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	ACHN_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-100	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.0533248821467198	none		DCHS2_1_111111111	Context-specific genetic dependencies (100)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LAMA84_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-101	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.0563290200974062	none		DCHS2_1_111111111	Context-specific genetic dependencies (101)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LK2_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-102	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.179624913847197	none		DCHS2_1_111111111	Context-specific genetic dependencies (102)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN215_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-103	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.0530121878404613	none		DCHS2_1_111111111	Context-specific genetic dependencies (103)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN229_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-104	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.744883848212481	none		DCHS2_1_111111111	Context-specific genetic dependencies (104)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN235_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-105	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.68125660219596	none		DCHS2_1_111111111	Context-specific genetic dependencies (105)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN319_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-106	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.344271669526596	none		DCHS2_1_111111111	Context-specific genetic dependencies (106)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN340_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-107	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.02518661401717	none		DCHS2_1_111111111	Context-specific genetic dependencies (107)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN382_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-108	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.16497860323017	none		DCHS2_1_111111111	Context-specific genetic dependencies (108)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN428_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-109	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.4577659816684	Decreased shRNA abundance (Z-score < -2)		DCHS2_1_111111111	Context-specific genetic dependencies (109)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN443_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-11	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.46152241917529	none		DCHS2_1_111111111	Context-specific genetic dependencies (11)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	AGS_STOMACH	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-110	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.380297851531877	none		DCHS2_1_111111111	Context-specific genetic dependencies (110)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LN464_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-111	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.911565585103103	none		DCHS2_1_111111111	Context-specific genetic dependencies (111)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LNZ308_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-112	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.206045829313545	none		DCHS2_1_111111111	Context-specific genetic dependencies (112)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LOVO_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-113	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.784490814990625	none		DCHS2_1_111111111	Context-specific genetic dependencies (113)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LS411N_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-114	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.200957521304455	none		DCHS2_1_111111111	Context-specific genetic dependencies (114)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	LS513_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-115	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.650144374636645	none		DCHS2_1_111111111	Context-specific genetic dependencies (115)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MCF7_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-116	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.03524478559645	none		DCHS2_1_111111111	Context-specific genetic dependencies (116)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MDAMB453_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-117	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.226041382286798	none		DCHS2_1_111111111	Context-specific genetic dependencies (117)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MIAPACA2_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-118	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.76487062934483	none		DCHS2_1_111111111	Context-specific genetic dependencies (118)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MKN7_STOMACH	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-119	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.317021376346831	none		DCHS2_1_111111111	Context-specific genetic dependencies (119)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MM1S_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-12	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.156222897879955	none		DCHS2_1_111111111	Context-specific genetic dependencies (12)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	AM38_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-120	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.194363017653169	none		DCHS2_1_111111111	Context-specific genetic dependencies (120)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MOLM13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-121	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.43627088123413	none		DCHS2_1_111111111	Context-specific genetic dependencies (121)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MONOMAC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-122	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.594788505993679	none		DCHS2_1_111111111	Context-specific genetic dependencies (122)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MONOMAC6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-123	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.285472559305926	none		DCHS2_1_111111111	Context-specific genetic dependencies (123)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	MV411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-124	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.599252977525097	none		DCHS2_1_111111111	Context-specific genetic dependencies (124)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NALM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-125	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.0778687102314855	none		DCHS2_1_111111111	Context-specific genetic dependencies (125)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NB4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-126	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.170104115154191	none		DCHS2_1_111111111	Context-specific genetic dependencies (126)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH1299_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-127	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.392957395056402	none		DCHS2_1_111111111	Context-specific genetic dependencies (127)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH1437_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-128	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.0293223840320101	none		DCHS2_1_111111111	Context-specific genetic dependencies (128)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH1650_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-129	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.410462168679127	none		DCHS2_1_111111111	Context-specific genetic dependencies (129)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH1792_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-13	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.358465458542285	none		DCHS2_1_111111111	Context-specific genetic dependencies (13)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	AML193_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-130	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.645711940931965	none		DCHS2_1_111111111	Context-specific genetic dependencies (130)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH196_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-131	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.717231940585364	none		DCHS2_1_111111111	Context-specific genetic dependencies (131)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH1975_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-132	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.270453244741662	none		DCHS2_1_111111111	Context-specific genetic dependencies (132)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH2052_PLEURA	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-133	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.833655971270518	none		DCHS2_1_111111111	Context-specific genetic dependencies (133)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH2122_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-134	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.30252089368687	Decreased shRNA abundance (Z-score < -2)		DCHS2_1_111111111	Context-specific genetic dependencies (134)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH2171_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-135	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.736744717432652	none		DCHS2_1_111111111	Context-specific genetic dependencies (135)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH23_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-136	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.402029361586603	none		DCHS2_1_111111111	Context-specific genetic dependencies (136)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH2452_PLEURA	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-137	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.332129217044967	none		DCHS2_1_111111111	Context-specific genetic dependencies (137)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH441_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-138	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	1.2107889126442	none		DCHS2_1_111111111	Context-specific genetic dependencies (138)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH508_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-139	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.04795249938305	none		DCHS2_1_111111111	Context-specific genetic dependencies (139)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH660_PROSTATE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-14	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.0653829618760857	none		DCHS2_1_111111111	Context-specific genetic dependencies (14)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	ASPC1_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-140	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.272071980407221	none		DCHS2_1_111111111	Context-specific genetic dependencies (140)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH661_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-141	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.85696115119715	none		DCHS2_1_111111111	Context-specific genetic dependencies (141)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH716_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-142	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.101293177508456	none		DCHS2_1_111111111	Context-specific genetic dependencies (142)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIH838_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-143	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	1.07234408505794	none		DCHS2_1_111111111	Context-specific genetic dependencies (143)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NCIN87_STOMACH	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-144	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.227232841813667	none		DCHS2_1_111111111	Context-specific genetic dependencies (144)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NIHOVCAR3_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-145	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.305867715558866	none		DCHS2_1_111111111	Context-specific genetic dependencies (145)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	NOMO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-146	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.981538816195541	none		DCHS2_1_111111111	Context-specific genetic dependencies (146)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OAW42_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-147	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.598797031954738	none		DCHS2_1_111111111	Context-specific genetic dependencies (147)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OCIAML2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-148	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.00459963715534447	none		DCHS2_1_111111111	Context-specific genetic dependencies (148)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-149	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.107445577312217	none		DCHS2_1_111111111	Context-specific genetic dependencies (149)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-15	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.144190876058783	none		DCHS2_1_111111111	Context-specific genetic dependencies (15)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	BT20_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-150	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.310626585816258	none		DCHS2_1_111111111	Context-specific genetic dependencies (150)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OE33_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-151	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.47630497176174	none		DCHS2_1_111111111	Context-specific genetic dependencies (151)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OELE_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-152	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.98713242275952	none		DCHS2_1_111111111	Context-specific genetic dependencies (152)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OPM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-153	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.447294681108041	none		DCHS2_1_111111111	Context-specific genetic dependencies (153)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OV7_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-154	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.0389196615736575	none		DCHS2_1_111111111	Context-specific genetic dependencies (154)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OV90_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-155	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.68908110753224	none		DCHS2_1_111111111	Context-specific genetic dependencies (155)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OVCAR4_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-156	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.646025516726123	none		DCHS2_1_111111111	Context-specific genetic dependencies (156)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OVCAR8_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-157	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.74015815544835	none		DCHS2_1_111111111	Context-specific genetic dependencies (157)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	OVISE_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-158	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	1.20510806033335	none		DCHS2_1_111111111	Context-specific genetic dependencies (158)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	PANC0327_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-159	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.229047685796585	none		DCHS2_1_111111111	Context-specific genetic dependencies (159)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	PANC0813_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-16	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.108648246838237	none		DCHS2_1_111111111	Context-specific genetic dependencies (16)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	BT474_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-160	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.136887308601628	none		DCHS2_1_111111111	Context-specific genetic dependencies (160)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	PANC1005_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-161	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.383678968267096	none		DCHS2_1_111111111	Context-specific genetic dependencies (161)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	PLB985_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-162	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.332952489812388	none		DCHS2_1_111111111	Context-specific genetic dependencies (162)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	PSN1_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-163	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.398162107962998	none		DCHS2_1_111111111	Context-specific genetic dependencies (163)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	QGP1_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-164	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.00848391139448	none		DCHS2_1_111111111	Context-specific genetic dependencies (164)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-165	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.692282994462102	none		DCHS2_1_111111111	Context-specific genetic dependencies (165)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	RKN_SOFT_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-166	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.239468008401875	none		DCHS2_1_111111111	Context-specific genetic dependencies (166)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	RKO_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-167	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	1.14373035806683	none		DCHS2_1_111111111	Context-specific genetic dependencies (167)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	RMGI_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-168	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.111035126116377	none		DCHS2_1_111111111	Context-specific genetic dependencies (168)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	RMUGS_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-169	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.0627500777474575	none		DCHS2_1_111111111	Context-specific genetic dependencies (169)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	RS411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-17	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.422171614455052	none		DCHS2_1_111111111	Context-specific genetic dependencies (17)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	BXPC3_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-170	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	1.54834290714054	Increased shRNA abundance (Z-score > 2)		DCHS2_1_111111111	Context-specific genetic dependencies (170)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	RT112_URINARY_TRACT	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-171	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.018527913455046	none		DCHS2_1_111111111	Context-specific genetic dependencies (171)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-172	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.46233028868139	none		DCHS2_1_111111111	Context-specific genetic dependencies (172)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SF126_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-173	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.700807614862724	none		DCHS2_1_111111111	Context-specific genetic dependencies (173)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SF172_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-174	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.272834475861886	none		DCHS2_1_111111111	Context-specific genetic dependencies (174)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SF295_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-175	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.211451039195055	none		DCHS2_1_111111111	Context-specific genetic dependencies (175)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SF767_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-176	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.953488416097788	none		DCHS2_1_111111111	Context-specific genetic dependencies (176)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SJSA1_BONE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-177	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.281791881834911	none		DCHS2_1_111111111	Context-specific genetic dependencies (177)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SKCO1_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-178	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.420728325975706	none		DCHS2_1_111111111	Context-specific genetic dependencies (178)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SKMEL5_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-179	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.352753672036653	none		DCHS2_1_111111111	Context-specific genetic dependencies (179)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SKMM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-18	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	1.29769196738186	Increased shRNA abundance (Z-score > 2)		DCHS2_1_111111111	Context-specific genetic dependencies (18)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	C2BBE1_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-180	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.54784849077221	Decreased shRNA abundance (Z-score < -2)		DCHS2_1_111111111	Context-specific genetic dependencies (180)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SKNO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-181	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.30259907912784	none		DCHS2_1_111111111	Context-specific genetic dependencies (181)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SKOV3_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-182	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.400954224107315	none		DCHS2_1_111111111	Context-specific genetic dependencies (182)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SKRC20_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-183	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.402592524077096	none		DCHS2_1_111111111	Context-specific genetic dependencies (183)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SLR20_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-184	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.782139617037703	none		DCHS2_1_111111111	Context-specific genetic dependencies (184)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SLR21_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-185	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.549175274008307	none		DCHS2_1_111111111	Context-specific genetic dependencies (185)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SLR23_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-186	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.7710595901411	none		DCHS2_1_111111111	Context-specific genetic dependencies (186)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SLR24_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-187	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.580042652912909	none		DCHS2_1_111111111	Context-specific genetic dependencies (187)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SLR25_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-188	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.519658395188803	none		DCHS2_1_111111111	Context-specific genetic dependencies (188)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SLR26_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-189	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.16272274418009	none		DCHS2_1_111111111	Context-specific genetic dependencies (189)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SNU1105_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-19	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.332934547659976	none		DCHS2_1_111111111	Context-specific genetic dependencies (19)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	C32_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-190	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.760780104528978	none		DCHS2_1_111111111	Context-specific genetic dependencies (190)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SNU840_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-191	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.823308134129034	none		DCHS2_1_111111111	Context-specific genetic dependencies (191)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SNUC1_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-192	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.0180532913084971	none		DCHS2_1_111111111	Context-specific genetic dependencies (192)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SNUC2A_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-193	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.0280593048557773	none		DCHS2_1_111111111	Context-specific genetic dependencies (193)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SU8686_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-194	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.306789310443063	none		DCHS2_1_111111111	Context-specific genetic dependencies (194)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SW1417_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-195	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.922246473666743	none		DCHS2_1_111111111	Context-specific genetic dependencies (195)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SW1783_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-196	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.22088848507391	none		DCHS2_1_111111111	Context-specific genetic dependencies (196)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SW480_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-197	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.312563851717752	none		DCHS2_1_111111111	Context-specific genetic dependencies (197)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	SW48_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-198	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.304440599715918	none		DCHS2_1_111111111	Context-specific genetic dependencies (198)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	T98G_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-199	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.800307820159108	none		DCHS2_1_111111111	Context-specific genetic dependencies (199)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TC71_BONE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-2	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.472996207662821	none		DCHS2_1_111111111	Context-specific genetic dependencies (2)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	697_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-20	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.234305461716025	none		DCHS2_1_111111111	Context-specific genetic dependencies (20)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CADOES1_BONE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-200	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.822146113106695	none		DCHS2_1_111111111	Context-specific genetic dependencies (200)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TCCSUP_URINARY_TRACT	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-201	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.332414304114548	none		DCHS2_1_111111111	Context-specific genetic dependencies (201)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TE10_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-202	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.09927432354764	none		DCHS2_1_111111111	Context-specific genetic dependencies (202)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TE15_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-203	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.0809325970289833	none		DCHS2_1_111111111	Context-specific genetic dependencies (203)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TE9_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-204	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.39230743653698	Decreased shRNA abundance (Z-score < -2)		DCHS2_1_111111111	Context-specific genetic dependencies (204)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-205	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.395640470594798	none		DCHS2_1_111111111	Context-specific genetic dependencies (205)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TOV112D_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-206	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.658382244495415	none		DCHS2_1_111111111	Context-specific genetic dependencies (206)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TOV21G_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-207	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.978264826904631	none		DCHS2_1_111111111	Context-specific genetic dependencies (207)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TT_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-208	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.227378513735533	none		DCHS2_1_111111111	Context-specific genetic dependencies (208)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	TYKNU_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-209	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.729816218052089	none		DCHS2_1_111111111	Context-specific genetic dependencies (209)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	U178_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-21	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.631434716858079	none		DCHS2_1_111111111	Context-specific genetic dependencies (21)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CAL120_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-210	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.461726627501332	none		DCHS2_1_111111111	Context-specific genetic dependencies (210)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	U251MG_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-211	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.585072288640813	none		DCHS2_1_111111111	Context-specific genetic dependencies (211)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	U343_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-212	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.104226088228059	none		DCHS2_1_111111111	Context-specific genetic dependencies (212)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	U87MG_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-213	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.659784063923415	none		DCHS2_1_111111111	Context-specific genetic dependencies (213)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	UOK101_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-214	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.353044366797036	none		DCHS2_1_111111111	Context-specific genetic dependencies (214)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	VCAP_PROSTATE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-215	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.552803102463823	none		DCHS2_1_111111111	Context-specific genetic dependencies (215)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	YKG1_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-216	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	1.49512091698583	Increased shRNA abundance (Z-score > 2)		DCHS2_1_111111111	Context-specific genetic dependencies (216)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	ZR7530_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-22	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.661654494839652	none		DCHS2_1_111111111	Context-specific genetic dependencies (22)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CAL51_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-23	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.240103727365836	none		DCHS2_1_111111111	Context-specific genetic dependencies (23)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CALU1_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-24	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.0139901811347096	none		DCHS2_1_111111111	Context-specific genetic dependencies (24)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CAOV3_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-25	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.746104460826447	none		DCHS2_1_111111111	Context-specific genetic dependencies (25)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CAOV4_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-26	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.540345125175065	none		DCHS2_1_111111111	Context-specific genetic dependencies (26)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CAS1_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-27	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.309094263158835	none		DCHS2_1_111111111	Context-specific genetic dependencies (27)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CFPAC1_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-28	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.383063238856922	none		DCHS2_1_111111111	Context-specific genetic dependencies (28)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CH157MN_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-29	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.813293897872975	none		DCHS2_1_111111111	Context-specific genetic dependencies (29)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COLO205_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-3	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.373274227069142	none		DCHS2_1_111111111	Context-specific genetic dependencies (3)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	786O_KIDNEY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-30	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.361515187263883	none		DCHS2_1_111111111	Context-specific genetic dependencies (30)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COLO704_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-31	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.438675395854472	none		DCHS2_1_111111111	Context-specific genetic dependencies (31)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COLO741_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-32	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.493243002447919	none		DCHS2_1_111111111	Context-specific genetic dependencies (32)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COLO783_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-33	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.839617565560234	none		DCHS2_1_111111111	Context-specific genetic dependencies (33)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	CORL23_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-34	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.281748403822896	none		DCHS2_1_111111111	Context-specific genetic dependencies (34)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COV362_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-35	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.00888557147608726	none		DCHS2_1_111111111	Context-specific genetic dependencies (35)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COV434_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-36	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.721100945214137	none		DCHS2_1_111111111	Context-specific genetic dependencies (36)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COV504_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-37	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.146743948659474	none		DCHS2_1_111111111	Context-specific genetic dependencies (37)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	COV644_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-38	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.0760860641491941	none		DCHS2_1_111111111	Context-specific genetic dependencies (38)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	DBTRG05MG_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-39	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.203553878541146	none		DCHS2_1_111111111	Context-specific genetic dependencies (39)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	DKMG_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-4	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.0305775609148551	none		DCHS2_1_111111111	Context-specific genetic dependencies (4)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	A1207_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-40	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.548481994169034	none		DCHS2_1_111111111	Context-specific genetic dependencies (40)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	DLD1_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-41	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	1.03633910783221	none		DCHS2_1_111111111	Context-specific genetic dependencies (41)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	EFE184_ENDOMETRIUM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-42	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.4326164376095	none		DCHS2_1_111111111	Context-specific genetic dependencies (42)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	EFM19_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-43	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.576918660343983	none		DCHS2_1_111111111	Context-specific genetic dependencies (43)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	EFO21_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-44	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.45102151537524	none		DCHS2_1_111111111	Context-specific genetic dependencies (44)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	EFO27_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-45	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.0859776832604888	none		DCHS2_1_111111111	Context-specific genetic dependencies (45)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	EW8_BONE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-46	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	1.03417112294062	none		DCHS2_1_111111111	Context-specific genetic dependencies (46)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	EWS502_BONE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-47	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.50715081735639	none		DCHS2_1_111111111	Context-specific genetic dependencies (47)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	F36P_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-48	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.571543080825802	none		DCHS2_1_111111111	Context-specific genetic dependencies (48)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	GB1_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-49	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.667720324235396	none		DCHS2_1_111111111	Context-specific genetic dependencies (49)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	GP2D_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-5	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.494585664222579	none		DCHS2_1_111111111	Context-specific genetic dependencies (5)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	A172_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-50	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.417301918318906	none		DCHS2_1_111111111	Context-specific genetic dependencies (50)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC1187_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-51	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.086575589025664	none		DCHS2_1_111111111	Context-specific genetic dependencies (51)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC1395_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-52	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.642175190528795	none		DCHS2_1_111111111	Context-specific genetic dependencies (52)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC1954_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-53	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	1.70861275669556	Increased shRNA abundance (Z-score > 2)		DCHS2_1_111111111	Context-specific genetic dependencies (53)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC2218_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-54	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.210490256303631	none		DCHS2_1_111111111	Context-specific genetic dependencies (54)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC2814_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-55	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.0630662512620998	none		DCHS2_1_111111111	Context-specific genetic dependencies (55)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC364_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-56	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.360294984761031	none		DCHS2_1_111111111	Context-specific genetic dependencies (56)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC44_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-57	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.489738225184968	none		DCHS2_1_111111111	Context-specific genetic dependencies (57)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC70_BREAST	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-58	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.503998977722026	none		DCHS2_1_111111111	Context-specific genetic dependencies (58)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC827GR5_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-59	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.142732118087326	none		DCHS2_1_111111111	Context-specific genetic dependencies (59)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCC827_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-6	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.08506576030326	none		DCHS2_1_111111111	Context-specific genetic dependencies (6)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	A204_SOFT_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-60	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.0748306914056505	none		DCHS2_1_111111111	Context-specific genetic dependencies (60)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HCT116_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-61	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.04296545421195	none		DCHS2_1_111111111	Context-specific genetic dependencies (61)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HEC1A_ENDOMETRIUM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-62	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.37408820814385	none		DCHS2_1_111111111	Context-specific genetic dependencies (62)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HEYA8_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-63	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.00618195134252	none		DCHS2_1_111111111	Context-specific genetic dependencies (63)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-64	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.424288838418564	none		DCHS2_1_111111111	Context-specific genetic dependencies (64)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HLF_LIVER	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-65	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.298674611017048	none		DCHS2_1_111111111	Context-specific genetic dependencies (65)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HNT34_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-66	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.0906506093828277	none		DCHS2_1_111111111	Context-specific genetic dependencies (66)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HPAC_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-67	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.277514362712297	none		DCHS2_1_111111111	Context-specific genetic dependencies (67)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HPAFII_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-68	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.719419692746992	none		DCHS2_1_111111111	Context-specific genetic dependencies (68)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HS683_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-69	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-1.02572044829176	none		DCHS2_1_111111111	Context-specific genetic dependencies (69)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HS766T_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-7	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.46323851977568	none		DCHS2_1_111111111	Context-specific genetic dependencies (7)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	A2058_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-70	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.699647087303348	none		DCHS2_1_111111111	Context-specific genetic dependencies (70)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HS944T_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-71	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.2791316280233	none		DCHS2_1_111111111	Context-specific genetic dependencies (71)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HT1197_URINARY_TRACT	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-72	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.802228613454206	none		DCHS2_1_111111111	Context-specific genetic dependencies (72)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HT29_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-73	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.746136183032786	none		DCHS2_1_111111111	Context-specific genetic dependencies (73)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HT55_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-74	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.0507721827405451	none		DCHS2_1_111111111	Context-specific genetic dependencies (74)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HUG1N_STOMACH	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-75	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.443915348401574	none		DCHS2_1_111111111	Context-specific genetic dependencies (75)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	HUTU80_SMALL_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-76	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.701244652775839	none		DCHS2_1_111111111	Context-specific genetic dependencies (76)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	IGR39_SKIN	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-77	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.063611484975782	none		DCHS2_1_111111111	Context-specific genetic dependencies (77)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	IGROV1_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-78	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.248986630128714	none		DCHS2_1_111111111	Context-specific genetic dependencies (78)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	IOMMLEE_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-79	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.455236705813785	none		DCHS2_1_111111111	Context-specific genetic dependencies (79)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	JHESOAD1_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-8	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.405630247488753	none		DCHS2_1_111111111	Context-specific genetic dependencies (8)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	A549_LUNG	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-80	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.0894501484882783	none		DCHS2_1_111111111	Context-specific genetic dependencies (80)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	JHOC5_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-81	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.277078736628068	none		DCHS2_1_111111111	Context-specific genetic dependencies (81)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	JHOM1_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-82	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.399450262538971	none		DCHS2_1_111111111	Context-specific genetic dependencies (82)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	JJN3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-83	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.49889429405597	none		DCHS2_1_111111111	Context-specific genetic dependencies (83)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-84	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.83123718541249	none		DCHS2_1_111111111	Context-specific genetic dependencies (84)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KALS1_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-85	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.42493188008585	none		DCHS2_1_111111111	Context-specific genetic dependencies (85)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KASUMI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-86	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.1056786390721	none		DCHS2_1_111111111	Context-specific genetic dependencies (86)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KM12_LARGE_INTESTINE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-87	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.61916633397738	none		DCHS2_1_111111111	Context-specific genetic dependencies (87)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KMS12BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-88	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.301509191649381	none		DCHS2_1_111111111	Context-specific genetic dependencies (88)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KNS60_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-89	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.480715198177312	none		DCHS2_1_111111111	Context-specific genetic dependencies (89)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KNS81_CENTRAL_NERVOUS_SYSTEM	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-9	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.515911753029367	none		DCHS2_1_111111111	Context-specific genetic dependencies (9)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	A673_BONE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-90	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.110788726808353	none		DCHS2_1_111111111	Context-specific genetic dependencies (90)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KP1NL_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-91	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.238267509876663	none		DCHS2_1_111111111	Context-specific genetic dependencies (91)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KP2_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-92	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.347461826567972	none		DCHS2_1_111111111	Context-specific genetic dependencies (92)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KP4_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-93	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.921048133046683	none		DCHS2_1_111111111	Context-specific genetic dependencies (93)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KURAMOCHI_OVARY	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-94	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.770640074559709	none		DCHS2_1_111111111	Context-specific genetic dependencies (94)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KYSE150_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-95	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	1.28364099232995	Increased shRNA abundance (Z-score > 2)		DCHS2_1_111111111	Context-specific genetic dependencies (95)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KYSE30_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-96	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.0405182017400595	none		DCHS2_1_111111111	Context-specific genetic dependencies (96)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KYSE450_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-97	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.118022698912192	none		DCHS2_1_111111111	Context-specific genetic dependencies (97)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	KYSE510_OESOPHAGUS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-98	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	0.0245139767007326	none		DCHS2_1_111111111	Context-specific genetic dependencies (98)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	L33_PANCREAS	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
GR00366-A-99	54798		DCHS2	TRCN0000055633, TRCN0000055634, TRCN0000055636, TRCN0000055637, TRCN0000055679, TRCN0000055680, TRCN0000055681, TRCN0000055682	-0.497376960723343	none		DCHS2_1_111111111	Context-specific genetic dependencies (99)	Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies	Cowley et al.	2014	25984343	Cell line	L363_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	shRNA abundance	Next-generation sequencing	TRC	shRNA	Genome-wide	Fold change	np (default cutoff applied: Z-score > 2 OR < -2)	Detailed information and analysis options for this large-scale screening project can be found at http://www.broadinstitute.org/achilles. The authors didn't provide a score cutoff - therefore we applied a default cutoff for phenotype assignment. (Note: We didn't confirm normal distribution of the data, so the Z-score cutoff should be interpreted with caution.)
	54798	54798	DCHS2		-0.03	none
	54798	54798	DCHS2		-0.020000000000000004	none
GR00376-A-1	54798	54798	DCHS2		0.221692293	none			Mitigators of SS1P-induced immunotoxicity	Whole-genome RNAi screen highlights components of the endoplasmic reticulum/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity	Pasetto et al.	2015	25713356	Cell line	KB cells	Viability	Luminescence	Ambion Silencer Select Version 4	Genome-wide	siRNA	RSA P-value	<0.001	SS1P was applied in a "high dose", ≈EC90, 13 ng/ml. Cutoff was derived from data submitted to Pubchem (ID 1117281). Reagent sequences but no ID
GR00376-A-2	54798	54798	DCHS2		0.491201508	none			Sensitizers of SS1P-induced immunotoxicity	Whole-genome RNAi screen highlights components of the endoplasmic reticulum/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity	Pasetto et al.	2015	25713356	Cell line	KB cells	Viability	Luminescence	Ambion Silencer Select Version 4	Genome-wide	siRNA	RSA P-value	<0.001	SS1P was applied in a "low dose", ≈EC30, 3 ng/ml. Cutoff was derived from data submitted to PubChem (ID 1117281). Reagent sequences but no ID
	54798	NM_017639	DCHS2		77.888	none