Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:10014
  • Symbol:HDAC5
  • Description:histone deacetylase 5

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10014 GO:0000122 IDA acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II 16236793 Process
10014 GO:0000122 IMP involved_in negative regulation of transcription by RNA polymerase II 10983972,19351956,23867755 Process
10014 GO:0010832 IMP involved_in negative regulation of myotube differentiation 10983972,11081517 Process
10014 GO:0016575 IDA involved_in histone deacetylation 10869435 Process
10014 GO:0040029 IMP involved_in epigenetic regulation of gene expression 24413532 Process
10014 GO:0043393 IMP involved_in regulation of protein binding 19071119 Process
10014 GO:0045944 IMP involved_in positive regulation of transcription by RNA polymerase II 19071119 Process
10014 GO:0051091 IMP involved_in positive regulation of DNA-binding transcription factor activity 19071119 Process
10014 GO:0090051 IMP involved_in negative regulation of cell migration involved in sprouting angiogenesis 19351956 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10014 GO:0000976 IDA contributes_to transcription cis-regulatory region binding 19351956 Function
10014 GO:0000978 IDA enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 24413532 Function
10014 GO:0001222 IPI enables transcription corepressor binding 10898795 Function
10014 GO:0004407 IDA enables histone deacetylase activity 10869435 Function
10014 GO:0005080 IPI enables protein kinase C binding 20188095 Function
10014 GO:0005515 IPI enables protein binding 10869435,15161933,15194749,15923258,16919237,17075044,17872950..... Function
10014 GO:0033558 IMP enables protein lysine deacetylase activity 23867755 Function
10014 GO:0042802 IPI enables identical protein binding 32296183 Function
10014 GO:0042826 IPI enables histone deacetylase binding 23867755 Function
10014 GO:0061629 IPI enables RNA polymerase II-specific DNA-binding transcription factor binding 19071119,20408817,23867755 Function
10014 GO:0140297 IPI enables DNA-binding transcription factor binding 12242305 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10014 GO:0005634 IDA located_in nucleus 10869435,11081517,23867755,26157139 Component
10014 GO:0005737 IDA located_in cytoplasm 10869435,11081517,26157139 Component
10014 GO:0005794 IDA located_in Golgi apparatus Component
10014 GO:0005829 IDA located_in cytosol Component
10014 GO:0016607 IDA located_in nuclear speck Component