Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:10016
  • Symbol:PDCD6
  • Description:programmed cell death 6

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10016 GO:0001938 IDA involved_in positive regulation of endothelial cell proliferation 21893193 Process
10016 GO:0006886 IDA involved_in intracellular protein transport 21122810 Process
10016 GO:0006888 IMP involved_in endoplasmic reticulum to Golgi vesicle-mediated transport 27716508,27813252 Process
10016 GO:0010595 IDA involved_in positive regulation of endothelial cell migration 21893193 Process
10016 GO:0014029 IMP involved_in neural crest formation 27716508 Process
10016 GO:0014032 IMP involved_in neural crest cell development 27716508 Process
10016 GO:0030948 IDA involved_in negative regulation of vascular endothelial growth factor receptor signaling pathway 21893193 Process
10016 GO:0032007 IDA involved_in negative regulation of TOR signaling 21893193 Process
10016 GO:0034605 IDA involved_in cellular response to heat 21122810 Process
10016 GO:0036324 IDA involved_in vascular endothelial growth factor receptor-2 signaling pathway 21893193 Process
10016 GO:0043280 IDA involved_in positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 16132846 Process
10016 GO:0045766 IDA involved_in positive regulation of angiogenesis 21893193 Process
10016 GO:0048208 IMP involved_in COPII vesicle coating 27716508 Process
10016 GO:0051898 IDA involved_in negative regulation of protein kinase B signaling 21893193 Process
10016 GO:1902527 IMP involved_in positive regulation of protein monoubiquitination 27716508 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10016 GO:0005509 IDA enables calcium ion binding 25667979 Function
10016 GO:0005515 IPI enables protein binding 11883939,16132846,16189514,17174262,17196169,18256029,18940611..... Function
10016 GO:0030674 IMP enables protein-macromolecule adaptor activity 19520058 Function
10016 GO:0042802 IPI enables identical protein binding 16189514,18940611,21988832,25416956 Function
10016 GO:0042803 IDA enables protein homodimerization activity 25667979 Function
10016 GO:0043495 IMP enables protein-membrane adaptor activity 16957052 Function
10016 GO:0046983 IPI enables protein dimerization activity 11883899 Function
10016 GO:0048306 IPI enables calcium-dependent protein binding 16957052,17196169,17214967,18256029,23924735,27716508..... Function
10016 GO:1990756 IMP enables ubiquitin ligase-substrate adaptor activity 27716508 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10016 GO:0005634 IDA located_in nucleus 16957052,17196169,21122810,27784779 Component
10016 GO:0005654 IDA located_in nucleoplasm Component
10016 GO:0005737 IDA located_in cytoplasm 21122810,27784779 Component
10016 GO:0005783 IDA located_in endoplasmic reticulum 17196169 Component
10016 GO:0005829 IDA located_in cytosol Component
10016 GO:0030127 IDA part_of COPII vesicle coat 27716508 Component
10016 GO:0031410 IDA located_in cytoplasmic vesicle 21122810 Component
10016 GO:0031463 IDA part_of Cul3-RING ubiquitin ligase complex 27716508 Component
10016 GO:0070062 HDA located_in extracellular exosome 19056867,20458337,23533145 Component
10016 GO:0070971 IDA located_in endoplasmic reticulum exit site 27813252 Component
10016 GO:0070971 IMP located_in endoplasmic reticulum exit site 16957052 Component