Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:1017
  • Symbol:CDK2
  • Description:cyclin dependent kinase 2

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1017 GO:0000307 IDA part_of cyclin-dependent protein kinase holoenzyme complex 1312467,8692841 Component
1017 GO:0005634 IDA located_in nucleus 10767298 Component
1017 GO:0005654 IDA located_in nucleoplasm 8245034 Component
1017 GO:0005737 IDA located_in cytoplasm 10767298 Component
1017 GO:0005768 IDA located_in endosome 21262353 Component
1017 GO:0005813 IDA located_in centrosome Component
1017 GO:0015030 IDA located_in Cajal body 10995387 Component
1017 GO:0097124 IDA part_of cyclin A2-CDK2 complex 1312467,8684460,8876165,11746698,15024385 Component
1017 GO:0097124 IPI part_of cyclin A2-CDK2 complex 12244298 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1017 GO:0004674 IGI enables protein serine/threonine kinase activity 26996940 Function
1017 GO:0004693 IDA enables cyclin-dependent protein serine/threonine kinase activity 21596315 Function
1017 GO:0005515 IPI enables protein binding 2227411,7630397,8242750,8521818,8601310,8684460,8756328,875662..... Function
1017 GO:0019904 IPI enables protein domain specific binding 8876165,15024385 Function
1017 GO:0030332 IDA enables cyclin binding 1653904,23781148 Function
1017 GO:0030332 IPI enables cyclin binding 1312467,15024385 Function
1017 GO:0035173 IDA contributes_to histone kinase activity 8692841 Function
1017 GO:0097472 IDA enables cyclin-dependent protein kinase activity 1312467,28666995 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1017 GO:0006468 IDA involved_in protein phosphorylation 12944431,28666995 Process
1017 GO:0006468 IMP involved_in protein phosphorylation 29203878 Process
1017 GO:0007099 IMP involved_in centriole replication 26297806 Process
1017 GO:0007265 IEP involved_in Ras protein signal transduction 9054499 Process
1017 GO:0008284 IDA involved_in positive regulation of cell population proliferation 10767298 Process
1017 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 23184662 Process
1017 GO:0031453 IDA involved_in positive regulation of heterochromatin formation 20935635 Process
1017 GO:0043687 IDA involved_in post-translational protein modification 11746698 Process