Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:1022
  • Symbol:CDK7
  • Description:cyclin dependent kinase 7

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1022 GO:0000079 IDA involved_in regulation of cyclin-dependent protein serine/threonine kinase activity 23622515 Process
1022 GO:0006366 IDA involved_in transcription by RNA polymerase II 8692841,9852112 Process
1022 GO:0006367 IDA involved_in transcription initiation at RNA polymerase II promoter 7533895 Process
1022 GO:0050821 IMP involved_in protein stabilization 23393140 Process
1022 GO:2000045 IDA involved_in regulation of G1/S transition of mitotic cell cycle 23622515 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1022 GO:0000439 IDA part_of transcription factor TFIIH core complex 8692841 Component
1022 GO:0001650 IDA located_in fibrillar center Component
1022 GO:0005634 IDA located_in nucleus 10958787,16109376 Component
1022 GO:0005654 IDA located_in nucleoplasm Component
1022 GO:0005675 IDA part_of transcription factor TFIIH holo complex 9852112 Component
1022 GO:0005829 IDA located_in cytosol Component
1022 GO:0005886 IDA located_in plasma membrane Component
1022 GO:0019907 IDA part_of cyclin-dependent protein kinase activating kinase holoenzyme complex 8692841,23622515 Component
1022 GO:0019907 IMP part_of cyclin-dependent protein kinase activating kinase holoenzyme complex 23393140 Component
1022 GO:0070516 IDA part_of CAK-ERCC2 complex 8692841 Component
1022 GO:0070985 IDA part_of transcription factor TFIIK complex 8692841 Component

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1022 GO:0005515 IPI enables protein binding 10801852,10958787,15530371,16327805,22939624,23393140,23455922..... Function
1022 GO:0008094 IDA enables ATP-dependent activity, acting on DNA 9852112 Function
1022 GO:0008353 IDA enables RNA polymerase II CTD heptapeptide repeat kinase activity 9852112,12721286 Function