Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:10297
  • Symbol:APC2
  • Description:APC regulator of WNT signaling pathway 2

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10297 GO:0000226 IMP involved_in microtubule cytoskeleton organization 25753423 Process
10297 GO:0090090 IDA involved_in negative regulation of canonical Wnt signaling pathway 9823329,10021369 Process
10297 GO:0090090 IMP involved_in negative regulation of canonical Wnt signaling pathway 26393419 Process
10297 GO:0090630 IMP involved_in activation of GTPase activity 25753423 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10297 GO:0005515 IPI enables protein binding 10644998,10646860 Function
10297 GO:0008013 IDA enables beta-catenin binding 9823329 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
10297 GO:0005737 IDA located_in cytoplasm 11691822 Component
10297 GO:0005794 IDA located_in Golgi apparatus 11691822 Component
10297 GO:0005829 IDA located_in cytosol Component
10297 GO:0005881 IDA colocalizes_with cytoplasmic microtubule 10644998,11691822,25753423 Component
10297 GO:0005884 IDA located_in actin filament 11691822 Component
10297 GO:0015630 IDA located_in microtubule cytoskeleton 10644998 Component
10297 GO:0016342 IDA part_of catenin complex 9823329 Component
10297 GO:0030496 IDA located_in midbody Component
10297 GO:0031258 IDA located_in lamellipodium membrane 11691822 Component
10297 GO:0045171 IDA located_in intercellular bridge Component
10297 GO:0048471 IDA located_in perinuclear region of cytoplasm 10644998,10646860,11691822 Component