Gene Ontology

Gene Info

• Species:Mouse (Mus musculus)
• GeneID:105787
• Symbol:Prkaa1
• Description:protein kinase, AMP-activated, alpha 1 catalytic subunit

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
105787	GO:0000785	IDA	part_of	chromatin	32822587	Component
105787	GO:0005634	IDA	located_in	nucleus	19833968	Component
105787	GO:0005737	IDA	located_in	cytoplasm	18381428,21768291	Component
105787	GO:0030424	IGI	located_in	axon	25788287	Component
105787	GO:0030425	IGI	located_in	dendrite	25788287	Component
105787	GO:0043025	IGI	located_in	neuronal cell body	25788287	Component

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
105787	GO:0003682	IDA	enables	chromatin binding	20647423	Function
105787	GO:0004674	IDA	enables	protein serine/threonine kinase activity	34077757	Function
105787	GO:0004679	IDA	enables	AMP-activated protein kinase activity	15878856,18439900,19833968,21258367,21459323	Function
105787	GO:0004679	IGI	enables	AMP-activated protein kinase activity	25788287,27430620	Function
105787	GO:0004679	IMP	enables	AMP-activated protein kinase activity	16308421	Function
105787	GO:0005515	IPI	enables	protein binding	15878856,19833968,21258367,21459323,24385485,25751139.....	Function
105787	GO:0140823	IDA	enables	histone H2BS36 kinase activity	20647423,32822587	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
105787	GO:0006006	IMP	acts_upstream_of_or_within	glucose metabolic process	12802337	Process
105787	GO:0008610	IDA	involved_in	lipid biosynthetic process	21459323	Process
105787	GO:0009411	IMP	involved_in	response to UV	20647423	Process
105787	GO:0010332	IMP	involved_in	response to gamma radiation	20647423	Process
105787	GO:0010508	IMP	involved_in	positive regulation of autophagy	21258367	Process
105787	GO:0010628	IMP	acts_upstream_of_or_within	positive regulation of gene expression	23926128	Process
105787	GO:0010629	IGI	involved_in	negative regulation of gene expression	27430620	Process
105787	GO:0019395	IMP	acts_upstream_of_or_within	fatty acid oxidation	12802337	Process
105787	GO:0031669	IDA	involved_in	cellular response to nutrient levels	21258367	Process
105787	GO:0032007	IMP	involved_in	negative regulation of TOR signaling	18439900	Process
105787	GO:0033135	IMP	acts_upstream_of_or_within	regulation of peptidyl-serine phosphorylation	23926128	Process
105787	GO:0034599	IGI	involved_in	cellular response to oxidative stress	27430620	Process
105787	GO:0042149	IDA	involved_in	cellular response to glucose starvation	21258367,34077757	Process
105787	GO:0042542	IMP	involved_in	response to hydrogen peroxide	20647423	Process
105787	GO:0042593	IMP	involved_in	glucose homeostasis	16308421	Process
105787	GO:0042752	IMP	involved_in	regulation of circadian rhythm	19833968	Process
105787	GO:0043066	IMP	involved_in	negative regulation of apoptotic process	18439900	Process
105787	GO:0045893	IDA	involved_in	positive regulation of DNA-templated transcription	20647423	Process
105787	GO:0048643	IMP	acts_upstream_of_or_within	positive regulation of skeletal muscle tissue development	23926128	Process
105787	GO:0050995	IDA	involved_in	negative regulation of lipid catabolic process	15878856	Process
105787	GO:0062028	IGI	involved_in	regulation of stress granule assembly	27430620	Process
105787	GO:0070507	IGI	involved_in	regulation of microtubule cytoskeleton organization	27430620	Process
105787	GO:0071277	IGI	involved_in	cellular response to calcium ion	25788287	Process
105787	GO:0071333	IGI	involved_in	cellular response to glucose stimulus	25788287	Process
105787	GO:0071380	IGI	acts_upstream_of_or_within	cellular response to prostaglandin E stimulus	23479225	Process
105787	GO:1903109	IMP	involved_in	positive regulation of mitochondrial transcription	23283301	Process
105787	GO:1903829	IGI	involved_in	positive regulation of protein localization	27430620	Process
105787	GO:1903955	IMP	involved_in	positive regulation of protein targeting to mitochondrion	23283301	Process
105787	GO:1904179	IDA	involved_in	positive regulation of adipose tissue development	32822587	Process
105787	GO:1904428	IGI	involved_in	negative regulation of tubulin deacetylation	27430620	Process
105787	GO:1990044	IDA	involved_in	protein localization to lipid droplet	34077757	Process
105787	GO:2000758	IGI	involved_in	positive regulation of peptidyl-lysine acetylation	27430620	Process