Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:11011
  • Symbol:TLK2
  • Description:tousled like kinase 2

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11011 GO:0004674 IDA enables protein serine/threonine kinase activity 12660173 Function
11011 GO:0005515 IPI enables protein binding 21903422,32296183 Function
11011 GO:0005524 IDA enables ATP binding 12660173 Function
11011 GO:0042802 IPI enables identical protein binding 32296183 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11011 GO:0005634 IDA located_in nucleus 9427565,10455159 Component
11011 GO:0005882 IDA located_in intermediate filament 10455159 Component
11011 GO:0048471 IDA located_in perinuclear region of cytoplasm 10455159 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11011 GO:0006468 IDA involved_in protein phosphorylation 12660173 Process
11011 GO:0006974 IDA involved_in DNA damage response 12660173 Process
11011 GO:0007059 IMP involved_in chromosome segregation 20705056 Process
11011 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 20016786 Process
11011 GO:0032435 IMP involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process 20016786 Process
11011 GO:0035556 IDA involved_in intracellular signal transduction 12660173 Process
11011 GO:0051179 EXP involved_in localization 29955062 Process
11011 GO:0071480 IDA involved_in cellular response to gamma radiation 12660173 Process
11011 GO:1902275 IDA involved_in regulation of chromatin organization 12660173 Process