Gene Ontology

Gene Info

• Species:Mouse (Mus musculus)
• GeneID:110355
• Symbol:Grk2
• Description:G protein-coupled receptor kinase 2

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
110355	GO:0002026	IGI	acts_upstream_of_or_within	regulation of the force of heart contraction	7761854	Process
110355	GO:0002029	IGI	acts_upstream_of_or_within	desensitization of G protein-coupled receptor signaling pathway	7761854	Process
110355	GO:0002029	IMP	acts_upstream_of_or_within	desensitization of G protein-coupled receptor signaling pathway	10338466	Process
110355	GO:0006468	IDA	acts_upstream_of_or_within	protein phosphorylation	15218143	Process
110355	GO:0007186	IDA	acts_upstream_of_or_within	G protein-coupled receptor signaling pathway	14712229	Process
110355	GO:0007507	IMP	acts_upstream_of_or_within	heart development	8917529	Process
110355	GO:0018105	IDA	acts_upstream_of_or_within	peptidyl-serine phosphorylation	17544362	Process
110355	GO:0018107	IDA	acts_upstream_of_or_within	peptidyl-threonine phosphorylation	17544362	Process
110355	GO:1901081	IMP	involved_in	negative regulation of relaxation of smooth muscle	30284927	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
110355	GO:0004672	IDA	enables	protein kinase activity	15218143	Function
110355	GO:0004674	IDA	enables	protein serine/threonine kinase activity	17544362	Function
110355	GO:0004703	IDA	enables	G protein-coupled receptor kinase activity	1869533,14712229	Function
110355	GO:0004703	IMP	enables	G protein-coupled receptor kinase activity	8917529	Function
110355	GO:0005515	IPI	enables	protein binding	15218143,17544362	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
110355	GO:0016020	IDA	located_in	membrane	15218143	Component