Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:11122
  • Symbol:PTPRT
  • Description:protein tyrosine phosphatase receptor type T

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11122 GO:0004725 IMP enables protein tyrosine phosphatase activity 16973135,17360477 Function
11122 GO:0005001 IDA enables transmembrane receptor protein tyrosine phosphatase activity 24846175 Function
11122 GO:0005515 IPI enables protein binding 16273344,19816407,21725282,24846175 Function
11122 GO:0008013 IPI enables beta-catenin binding 16973135 Function
11122 GO:0019903 IPI enables protein phosphatase binding 24846175 Function
11122 GO:0042803 IPI enables protein homodimerization activity 24846175 Function
11122 GO:0045294 IDA enables alpha-catenin binding 16973135 Function
11122 GO:0045295 IDA enables gamma-catenin binding 16973135 Function
11122 GO:0045296 IPI enables cadherin binding 16973135 Function
11122 GO:0070097 IPI enables delta-catenin binding 16973135 Function
11122 GO:0097677 IPI enables STAT family protein binding 17360477 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11122 GO:0005886 IDA located_in plasma membrane 18644975,24846175 Component
11122 GO:0009986 IDA located_in cell surface 18644975 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11122 GO:0006470 IDA involved_in protein dephosphorylation 16973135 Process
11122 GO:0007156 IDA involved_in homophilic cell adhesion via plasma membrane adhesion molecules 18644975 Process
11122 GO:0007169 IMP involved_in transmembrane receptor protein tyrosine kinase signaling pathway 16973135 Process
11122 GO:0030336 IMP involved_in negative regulation of cell migration 24846175 Process
11122 GO:0035335 IDA involved_in peptidyl-tyrosine dephosphorylation 17360477 Process
11122 GO:0071354 IDA involved_in cellular response to interleukin-6 17360477 Process
11122 GO:1904893 IDA involved_in negative regulation of receptor signaling pathway via STAT 17360477 Process
11122 GO:1904893 IMP involved_in negative regulation of receptor signaling pathway via STAT 24846175 Process
11122 GO:1990264 IDA involved_in peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity 24846175 Process