Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:11338
• Symbol:U2AF2
• Description:U2 small nuclear RNA auxiliary factor 2

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
11338	GO:0000398	IDA	involved_in	mRNA splicing, via spliceosome	1824937	Process
11338	GO:0031397	IDA	involved_in	negative regulation of protein ubiquitination	24389012	Process
11338	GO:0031397	IMP	involved_in	negative regulation of protein ubiquitination	24389012	Process
11338	GO:0033120	IDA	involved_in	positive regulation of RNA splicing	21536736	Process
11338	GO:0048025	IDA	involved_in	negative regulation of mRNA splicing, via spliceosome	15009664	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
11338	GO:0003723	HDA	enables	RNA binding	22658674,22681889	Function
11338	GO:0005515	IPI	enables	protein binding	9237760,9447963,10449420,11551507,12718882,16189514,16713569,1.....	Function
11338	GO:0019899	IPI	enables	enzyme binding	19574390	Function
11338	GO:0030628	IDA	enables	pre-mRNA 3'-splice site binding	2531895	Function
11338	GO:0140678	EXP	enables	molecular function inhibitor activity	32188783	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
11338	GO:0005634	IDA	located_in	nucleus	1824937	Component
11338	GO:0005681	IDA	part_of	spliceosomal complex	9731529	Component
11338	GO:0005681	IPI	part_of	spliceosomal complex	11551507,23273425	Component
11338	GO:0016607	IDA	located_in	nuclear speck	1824937,21984414	Component
11338	GO:0071004	IDA	part_of	U2-type prespliceosome	2531895	Component
11338	GO:0089701	IDA	part_of	U2AF complex	1824937,2531895	Component
11338	GO:0089701	IPI	part_of	U2AF complex	11551507,23273425	Component