Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:1147
  • Symbol:CHUK
  • Description:component of inhibitor of nuclear factor kappa B kinase complex

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1147 GO:0004672 IDA enables protein kinase activity 20434986 Function
1147 GO:0005515 IPI enables protein binding 8246997,9520446,9751060,10521409,10733566,11297557,11971985,12..... Function
1147 GO:0008384 IDA enables IkappaB kinase activity 9244310,9252186,9346484 Function
1147 GO:0042803 IDA enables protein homodimerization activity 23091055 Function
1147 GO:0046982 IDA enables protein heterodimerization activity 23091055 Function
1147 GO:0097110 IDA enables scaffold protein binding 23776175 Function
1147 GO:1990459 IPI enables transferrin receptor binding 23016877 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1147 GO:0005654 IDA located_in nucleoplasm Component
1147 GO:0005737 IDA located_in cytoplasm 30341167 Component
1147 GO:0005829 IDA located_in cytosol Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1147 GO:0006468 IDA involved_in protein phosphorylation 20434986 Process
1147 GO:0007249 IDA involved_in I-kappaB kinase/NF-kappaB signaling 9244310,9252186,9346484 Process
1147 GO:0007249 IMP involved_in I-kappaB kinase/NF-kappaB signaling 26514923 Process
1147 GO:0032088 IMP involved_in negative regulation of NF-kappaB transcription factor activity 11536016 Process
1147 GO:0032727 IMP involved_in positive regulation of interferon-alpha production 24784232 Process
1147 GO:0034142 IDA involved_in toll-like receptor 4 signaling pathway 26189595 Process
1147 GO:0034614 IMP involved_in cellular response to reactive oxygen species 26514923 Process
1147 GO:0038061 IDA involved_in NIK/NF-kappaB signaling 26189595 Process
1147 GO:0038061 IMP involved_in NIK/NF-kappaB signaling 26514923 Process
1147 GO:0043123 IMP involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling 23487264 Process
1147 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 26514923 Process
1147 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 23091055 Process
1147 GO:0071276 IMP involved_in cellular response to cadmium ion 26514923 Process
1147 GO:0071356 IDA involved_in cellular response to tumor necrosis factor 23091055 Process
1147 GO:0098586 IMP involved_in cellular response to virus 24784232 Process