Gene Ontology

Gene Info

• Species:Mouse (Mus musculus)
• GeneID:114716
• Symbol:Spred2
• Description:sprouty-related EVH1 domain containing 2

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
114716	GO:0005173	IPI	enables	stem cell factor receptor binding	12646235	Function
114716	GO:0005515	IPI	enables	protein binding	12646235,17974561,19822672	Function
114716	GO:0019901	IPI	enables	protein kinase binding	20736167	Function
114716	GO:0030291	IDA	enables	protein serine/threonine kinase inhibitor activity	20736167	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
114716	GO:0005886	IDA	located_in	plasma membrane	12646235	Component
114716	GO:0031410	IDA	located_in	cytoplasmic vesicle	15580519	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
114716	GO:0010719	IDA	involved_in	negative regulation of epithelial to mesenchymal transition	25576668	Process
114716	GO:0010801	IDA	involved_in	negative regulation of peptidyl-threonine phosphorylation	20736167	Process
114716	GO:0030512	IDA	involved_in	negative regulation of transforming growth factor beta receptor signaling pathway	25576668	Process
114716	GO:0043409	IMP	acts_upstream_of_or_within	negative regulation of MAPK cascade	12646235	Process
114716	GO:0043517	IDA	involved_in	positive regulation of DNA damage response, signal transduction by p53 class mediator	20736167	Process
114716	GO:0070373	IDA	involved_in	negative regulation of ERK1 and ERK2 cascade	29501879	Process
114716	GO:0090311	IDA	involved_in	regulation of protein deacetylation	20736167	Process
114716	GO:1902747	IDA	involved_in	negative regulation of lens fiber cell differentiation	29501879	Process