Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:114769
  • Symbol:CARD16
  • Description:caspase recruitment domain family member 16

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
114769 GO:0004869 IDA enables cysteine-type endopeptidase inhibitor activity 16920334 Function
114769 GO:0005515 IPI enables protein binding 11536016,11821383,15383541 Function
114769 GO:0019900 IPI enables kinase binding 11432859,11536016,15383541 Function
114769 GO:0042802 IDA enables identical protein binding 11432859 Function
114769 GO:0050700 IPI enables CARD domain binding 11821383 Function
114769 GO:0089720 IPI enables caspase binding 11432859,11536016,16920334 Function

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
114769 GO:0010804 IMP involved_in negative regulation of tumor necrosis factor-mediated signaling pathway 16920334 Process
114769 GO:0031665 IDA involved_in negative regulation of lipopolysaccharide-mediated signaling pathway 11432859 Process
114769 GO:0032091 IDA involved_in negative regulation of protein binding 11432859,11536016 Process
114769 GO:0032691 IDA involved_in negative regulation of interleukin-1 beta production 11432859,11536016,15383541,16920334 Process
114769 GO:0043123 IDA involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling 15383541 Process
114769 GO:0043154 IDA involved_in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 16920334 Process
114769 GO:0051092 IDA involved_in positive regulation of NF-kappaB transcription factor activity 11536016 Process
114769 GO:0071222 IDA involved_in cellular response to lipopolysaccharide 15383541 Process
114769 GO:0097340 IDA involved_in inhibition of cysteine-type endopeptidase activity 11432859 Process

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
114769 GO:0032991 IDA part_of protein-containing complex 11536016,11821383,15383541,16920334 Component
114769 GO:0097179 IDA part_of protease inhibitor complex 11432859 Component