Gene Ontology

Gene Info

• Species:Human (Homo sapiens)
• GeneID:115362
• Symbol:GBP5
• Description:guanylate binding protein 5

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
115362	GO:0000139	IDA	is_active_in	Golgi membrane	31091448	Component
115362	GO:0005737	IDA	located_in	cytoplasm	17266443	Component
115362	GO:0005794	IDA	is_active_in	Golgi apparatus	26996307,31091448	Component
115362	GO:0005794	IDA	located_in	Golgi apparatus	17266443,21151871	Component
115362	GO:0016020	HDA	located_in	membrane	19946888	Component
115362	GO:0048471	IDA	located_in	perinuclear region of cytoplasm	21151871	Component

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
115362	GO:0003924	IDA	enables	GTPase activity	26996307,33876762	Function
115362	GO:0004866	IDA	enables	endopeptidase inhibitor activity	31091448	Function
115362	GO:0005515	IPI	enables	protein binding	21151871,22461501,28514442	Function
115362	GO:0042802	IPI	enables	identical protein binding	16189514,20180847,21151871	Function
115362	GO:0042803	IDA	enables	protein homodimerization activity	21151871,33876762	Function
115362	GO:0140678	IDA	enables	molecular function inhibitor activity	31091448	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
115362	GO:0032731	IMP	involved_in	positive regulation of interleukin-1 beta production	22461501	Process
115362	GO:0034067	IDA	involved_in	protein localization to Golgi apparatus	21151871	Process
115362	GO:0051289	IDA	involved_in	protein homotetramerization	22461501	Process
115362	GO:0051607	IDA	involved_in	defense response to virus	26996307,31091448	Process
115362	GO:0071346	IEP	involved_in	cellular response to type II interferon	17266443	Process
115362	GO:1900227	IDA	involved_in	positive regulation of NLRP3 inflammasome complex assembly	22461501	Process