Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:11634
  • Symbol:Aire
  • Description:autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11634 GO:0001673 IDA located_in male germ cell nucleus 11156688 Component
11634 GO:0001674 IDA located_in female germ cell nucleus 11156688 Component
11634 GO:0005622 IDA located_in intracellular anatomical structure 17599412 Component
11634 GO:0005634 IDA located_in nucleus 11156688,11854172 Component
11634 GO:0005737 IDA located_in cytoplasm 11156688 Component
11634 GO:0016604 IDA located_in nuclear body 19015306 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11634 GO:0002458 IDA involved_in peripheral T cell tolerance induction 23993652 Process
11634 GO:0006366 IMP acts_upstream_of transcription by RNA polymerase II 17599412 Process
11634 GO:0006959 IMP acts_upstream_of_or_within humoral immune response 11854172 Process
11634 GO:0032722 IMP involved_in positive regulation of chemokine production 19923453 Process
11634 GO:0045060 IGI acts_upstream_of_or_within negative thymic T cell selection 23382543 Process
11634 GO:0045944 IDA acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 17599412 Process
11634 GO:0045944 IMP acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II 17599412 Process
11634 GO:0097536 IMP involved_in thymus epithelium morphogenesis 19015306 Process
11634 GO:2000410 IMP involved_in regulation of thymocyte migration 19923453 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
11634 GO:0042802 IPI enables identical protein binding 11533054 Function