Gene Ontology

Gene Info

• Species:Rat (Rattus norvegicus)
• GeneID:116477
• Symbol:Wnk1
• Description:WNK lysine deficient protein kinase 1

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
116477	GO:0000287	IMP	enables	magnesium ion binding	10828064	Function
116477	GO:0004674	IDA	enables	protein serine/threonine kinase activity	10828064,15081430,15350218,22544747,24803536,36318922.....	Function
116477	GO:0005515	IPI	enables	protein binding	15350218,16083423,16204408	Function
116477	GO:0005524	IDA	enables	ATP binding	10828064,15081430	Function
116477	GO:0019870	IDA	enables	potassium channel inhibitor activity	16775035	Function
116477	GO:0019901	IPI	enables	protein kinase binding	16083423	Function
116477	GO:0030291	IDA	enables	protein serine/threonine kinase inhibitor activity	15081430	Function
116477	GO:0140693	IDA	enables	molecular condensate scaffold activity	36318922	Function

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
116477	GO:0002028	IDA	involved_in	regulation of sodium ion transport	16204408	Process
116477	GO:0006468	IDA	involved_in	protein phosphorylation	10828064,15081430,24803536	Process
116477	GO:0006884	IDA	involved_in	cell volume homeostasis	36318922	Process
116477	GO:0010766	IDA	involved_in	negative regulation of sodium ion transport	16204408	Process
116477	GO:0033673	IDA	involved_in	negative regulation of kinase activity	15081430	Process
116477	GO:0035556	IDA	involved_in	intracellular signal transduction	10828064	Process
116477	GO:0046777	IDA	involved_in	protein autophosphorylation	10828064,15081430	Process
116477	GO:0050804	EXP	involved_in	modulation of chemical synaptic transmission	26126716	Process
116477	GO:0050804	IDA	involved_in	modulation of chemical synaptic transmission	26126716	Process
116477	GO:0050804	IMP	involved_in	modulation of chemical synaptic transmission	26126716	Process
116477	GO:0071277	IDA	involved_in	cellular response to calcium ion	24803536	Process
116477	GO:0071474	IDA	involved_in	cellular hyperosmotic response	36318922	Process
116477	GO:1903077	IDA	involved_in	negative regulation of protein localization to plasma membrane	17673510	Process

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
116477	GO:0005737	IDA	located_in	cytoplasm	10828064	Component
116477	GO:0005829	IDA	located_in	cytosol	25515571	Component
116477	GO:0016020	IDA	located_in	membrane	25515571	Component
116477	GO:0043232	IDA	is_active_in	intracellular non-membrane-bounded organelle	36318922	Component
116477	GO:0098982	EXP	is_active_in	GABA-ergic synapse	26126716	Component
116477	GO:0098982	IDA	is_active_in	GABA-ergic synapse	26126716	Component
116477	GO:0098982	IMP	is_active_in	GABA-ergic synapse	26126716	Component