Gene Ontology

Gene Info

• Species:Rat (Rattus norvegicus)
• GeneID:116590
• Symbol:Mapk1
• Description:mitogen activated protein kinase 1

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
116590	GO:0000165	IMP	involved_in	MAPK cascade	17310240	Process
116590	GO:0006468	IDA	involved_in	protein phosphorylation	12944431,15027896,26950759	Process
116590	GO:0006468	IMP	involved_in	protein phosphorylation	19524539	Process
116590	GO:0008284	IEP	involved_in	positive regulation of cell population proliferation	15583728	Process
116590	GO:0009636	IDA	involved_in	response to toxic substance	17651772	Process
116590	GO:0015966	IMP	involved_in	diadenosine tetraphosphate biosynthetic process	19524539	Process
116590	GO:0018105	IDA	acts_upstream_of_or_within	peptidyl-serine phosphorylation	7768935	Process
116590	GO:0018105	IMP	involved_in	peptidyl-serine phosphorylation	16955078	Process
116590	GO:0019233	IMP	involved_in	sensory perception of pain	11356865	Process
116590	GO:0030335	IEP	involved_in	positive regulation of cell migration	15917991	Process
116590	GO:0035094	IGI	involved_in	response to nicotine	11404397	Process
116590	GO:0035556	IDA	involved_in	intracellular signal transduction	12072413	Process
116590	GO:0042307	IMP	involved_in	positive regulation of protein import into nucleus	19524539	Process
116590	GO:0043627	IDA	involved_in	response to estrogen	11751611	Process
116590	GO:0045727	IMP	involved_in	positive regulation of translation	15027896	Process
116590	GO:0045893	IMP	involved_in	positive regulation of DNA-templated transcription	19524539	Process
116590	GO:0046697	IDA	involved_in	decidualization	21248290	Process
116590	GO:0060045	IMP	involved_in	positive regulation of cardiac muscle cell proliferation	26884868	Process
116590	GO:0070371	IMP	involved_in	ERK1 and ERK2 cascade	19524539	Process
116590	GO:0071310	IDA	involved_in	cellular response to organic substance	12487375	Process

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
116590	GO:0003690	IDA	enables	double-stranded DNA binding	26950759	Function
116590	GO:0004674	IDA	enables	protein serine/threonine kinase activity	7768935	Function
116590	GO:0004707	IDA	enables	MAP kinase activity	7889942,15027896	Function
116590	GO:0004707	IMP	enables	MAP kinase activity	16955078,19524539	Function
116590	GO:0005515	IPI	enables	protein binding	12944431,15781236,19200235,21070949,24567387	Function
116590	GO:0005524	IDA	enables	ATP binding	15027896	Function
116590	GO:0019901	IPI	enables	protein kinase binding	16943189	Function
116590	GO:0031435	IPI	enables	mitogen-activated protein kinase kinase kinase binding	12049732	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
116590	GO:0005654	IDA	located_in	nucleoplasm	7889942	Component
116590	GO:0005737	IDA	located_in	cytoplasm	24567387	Component
116590	GO:0005886	IDA	located_in	plasma membrane	24567387	Component
116590	GO:0005901	IDA	located_in	caveola	24567387	Component
116590	GO:0014069	IDA	is_active_in	postsynaptic density	7478291	Component
116590	GO:0030424	IDA	located_in	axon	9714150	Component
116590	GO:0032839	IDA	located_in	dendrite cytoplasm	9714150	Component
116590	GO:0032991	IDA	part_of	protein-containing complex	15781236	Component
116590	GO:0043204	IDA	located_in	perikaryon	9714150	Component