Gene Ontology

Gene Info

• Species:Rat (Rattus norvegicus)
• GeneID:116643
• Symbol:Vcp
• Description:valosin-containing protein

Function

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
116643	GO:0005515	IPI	enables	protein binding	9214505,10811609,16601695,20691684	Function
116643	GO:0005524	IDA	enables	ATP binding	7806566	Function
116643	GO:0005524	IMP	enables	ATP binding	18332143	Function
116643	GO:0016887	IDA	enables	ATP hydrolysis activity	7806566	Function
116643	GO:0016887	IMP	enables	ATP hydrolysis activity	18332143	Function
116643	GO:0042802	IDA	enables	identical protein binding	7806566	Function
116643	GO:0042802	IPI	enables	identical protein binding	7806566,18332143	Function
116643	GO:0043531	IMP	enables	ADP binding	18332143	Function
116643	GO:0044877	IPI	enables	protein-containing complex binding	10811609	Function

Component

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
116643	GO:0005829	IDA	located_in	cytosol	9214505,23444373	Component
116643	GO:0034098	EXP	part_of	VCP-NPL4-UFD1 AAA ATPase complex	22232657	Component
116643	GO:0034098	IDA	part_of	VCP-NPL4-UFD1 AAA ATPase complex	10811609	Component
116643	GO:0098978	IDA	is_active_in	glutamatergic synapse	22105171	Component
116643	GO:0098978	IMP	is_active_in	glutamatergic synapse	22105171	Component
116643	GO:1990730	IPI	part_of	VCP-NSFL1C complex	9214505,10811609	Component

Process

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GeneID	GO_ID	Evidence	Qualifier	GO_term	Pubmed ID	Category
116643	GO:0006888	IMP	involved_in	endoplasmic reticulum to Golgi vesicle-mediated transport	7806566	Process
116643	GO:0030433	EXP	involved_in	ubiquitin-dependent ERAD pathway	12847084	Process
116643	GO:0030970	EXP	involved_in	retrograde protein transport, ER to cytosol	12847084	Process
116643	GO:0050807	IDA	involved_in	regulation of synapse organization	22105171	Process
116643	GO:0050807	IMP	involved_in	regulation of synapse organization	22105171	Process
116643	GO:2000060	IMP	involved_in	positive regulation of ubiquitin-dependent protein catabolic process	16103111	Process