Gene Ontology

Gene Info

  • Species:Rat (Rattus norvegicus)
  • GeneID:116667
  • Symbol:Map3k1
  • Description:mitogen-activated protein kinase kinase kinase 1

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
116667 GO:0000165 IDA involved_in MAPK cascade 9110999 Process
116667 GO:0000209 IMP involved_in protein polyubiquitination 12049732 Process
116667 GO:0006468 IDA involved_in protein phosphorylation 9110999 Process
116667 GO:0006511 IGI involved_in ubiquitin-dependent protein catabolic process 12049732 Process
116667 GO:0018105 IDA involved_in peptidyl-serine phosphorylation 7624324 Process
116667 GO:0032232 IDA involved_in negative regulation of actin filament bundle assembly 9155015 Process
116667 GO:0043065 IMP involved_in positive regulation of apoptotic process 17101801 Process
116667 GO:0043406 IDA involved_in positive regulation of MAP kinase activity 9110999 Process
116667 GO:0043410 IDA involved_in positive regulation of MAPK cascade 7624324,9110999 Process
116667 GO:0043507 IDA involved_in positive regulation of JUN kinase activity 9110999 Process
116667 GO:0045893 IMP involved_in positive regulation of DNA-templated transcription 20128690 Process
116667 GO:0045944 IDA involved_in positive regulation of transcription by RNA polymerase II 9155015 Process
116667 GO:0046330 IDA involved_in positive regulation of JNK cascade 9110999 Process
116667 GO:0046777 IDA involved_in protein autophosphorylation 12049732 Process
116667 GO:0046777 IMP involved_in protein autophosphorylation 11784851 Process
116667 GO:0050434 IDA involved_in positive regulation of viral transcription 11746500 Process
116667 GO:0090263 IMP involved_in positive regulation of canonical Wnt signaling pathway 20128690 Process

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
116667 GO:0004706 IDA enables JUN kinase kinase kinase activity 9110999 Function
116667 GO:0004709 IDA enables MAP kinase kinase kinase activity 7624324,9110999 Function
116667 GO:0004842 IMP enables ubiquitin-protein transferase activity 12049732 Function
116667 GO:0005515 IPI enables protein binding 25260751 Function
116667 GO:0008432 IPI enables JUN kinase binding 16006144 Function
116667 GO:0031434 IPI enables mitogen-activated protein kinase kinase binding 7624324,16006144 Function
116667 GO:0044877 IDA enables protein-containing complex binding 11784851 Function
116667 GO:0046625 IPI enables sphingolipid binding 15164763 Function
116667 GO:0051019 IPI enables mitogen-activated protein kinase binding 12049732 Function