Gene Ontology

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:12289
  • Symbol:Cacna1d
  • Description:calcium channel, voltage-dependent, L type, alpha 1D subunit

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12289 GO:0005515 IPI enables protein binding 10468580 Function
12289 GO:0008331 IDA enables high voltage-gated calcium channel activity 12900400 Function
12289 GO:0030506 IPI enables ankyrin binding 21859974 Function
12289 GO:0086059 IMP enables voltage-gated calcium channel activity involved SA node cell action potential 15932895 Function
12289 GO:0099626 IDA enables voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels 10929716 Function
12289 GO:0099626 IMP enables voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels 10929716 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12289 GO:0005886 IDA located_in plasma membrane 10468580,18832177,21859974 Component
12289 GO:0030018 IDA located_in Z disc 17110593 Component
12289 GO:0048787 IDA is_active_in presynaptic active zone membrane 16354915 Component
12289 GO:0098683 IDA is_active_in cochlear hair cell ribbon synapse 10929716,16354915 Component
12289 GO:0098683 IMP is_active_in cochlear hair cell ribbon synapse 10929716 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
12289 GO:0007188 IMP acts_upstream_of_or_within adenylate cyclase-modulating G protein-coupled receptor signaling pathway 16706838 Process
12289 GO:0007605 IMP acts_upstream_of_or_within sensory perception of sound 17074442 Process
12289 GO:0045762 IDA involved_in positive regulation of adenylate cyclase activity 24086669 Process
12289 GO:0051649 IMP acts_upstream_of_or_within establishment of localization in cell 12700358 Process
12289 GO:0060372 IMP involved_in regulation of atrial cardiac muscle cell membrane repolarization 17110593 Process
12289 GO:0070588 IMP acts_upstream_of_or_within calcium ion transmembrane transport 12700358 Process
12289 GO:0086046 IMP acts_upstream_of_or_within membrane depolarization during SA node cell action potential 12700358 Process
12289 GO:0086091 IMP acts_upstream_of_or_within regulation of heart rate by cardiac conduction 12700358 Process
12289 GO:1901016 IMP involved_in regulation of potassium ion transmembrane transporter activity 17110593 Process
12289 GO:1901379 IMP involved_in regulation of potassium ion transmembrane transport 17110593 Process