Gene Ontology

Gene Info

  • Species:Human (Homo sapiens)
  • GeneID:1230
  • Symbol:CCR1
  • Description:C-C motif chemokine receptor 1

Function

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1230 GO:0004435 IDA enables phosphatidylinositol phospholipase C activity 10734056 Function
1230 GO:0004950 IDA enables chemokine receptor activity 10660125 Function
1230 GO:0005515 IPI enables protein binding 8699119,15001559,15474493,28381538,32296183 Function
1230 GO:0016493 IDA enables C-C chemokine receptor activity 10734056 Function
1230 GO:0019957 IPI enables C-C chemokine binding 7545673,8699119,10660125,15764707 Function
1230 GO:0035717 IPI enables chemokine (C-C motif) ligand 7 binding 7545673,10660125 Function
1230 GO:0071791 IPI enables chemokine (C-C motif) ligand 5 binding 7545673,8699119,10660125,10734056 Function

Component

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1230 GO:0005886 IDA located_in plasma membrane 10660125,15474493,18587271 Component
1230 GO:0005886 IMP located_in plasma membrane 15001559 Component
1230 GO:0009897 IDA located_in external side of plasma membrane 10706735 Component

Process

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GeneID GO_ID Evidence Qualifier GO_term Pubmed ID Category
1230 GO:0006816 IDA involved_in calcium ion transport 10734056 Process
1230 GO:0006874 IDA involved_in intracellular calcium ion homeostasis 10734056 Process
1230 GO:0006887 IDA involved_in exocytosis 10734056 Process
1230 GO:0006955 IDA involved_in immune response 10734056 Process
1230 GO:0007204 IDA involved_in positive regulation of cytosolic calcium ion concentration 10734056 Process
1230 GO:0007267 IDA involved_in cell-cell signaling 10734056 Process
1230 GO:0010629 IMP involved_in negative regulation of gene expression 21403648 Process
1230 GO:0030335 IMP involved_in positive regulation of cell migration 24056371 Process
1230 GO:0030502 IMP involved_in negative regulation of bone mineralization 21403648 Process
1230 GO:0045672 IMP involved_in positive regulation of osteoclast differentiation 21403648 Process
1230 GO:0051928 IDA involved_in positive regulation of calcium ion transport 15764707 Process
1230 GO:0070098 IDA involved_in chemokine-mediated signaling pathway 21403648 Process
1230 GO:0070374 IMP involved_in positive regulation of ERK1 and ERK2 cascade 21403648 Process
1230 GO:0090026 IDA involved_in positive regulation of monocyte chemotaxis 18587271 Process